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Suzanne R. Pfeffer - Publications

Affiliations: 
Biochemistry Stanford University, Palo Alto, CA 
Area:
Receptor trafficking in human cells
Website:
http://pfeffer.stanford.edu/

146/208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yeshaw WM, Adhikari A, Chiang CY, Dhekne HS, Wawro PS, Pfeffer SR. Localization of PPM1H phosphatase tunes Parkinson's disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2315171120. PMID 37889931 DOI: 10.1073/pnas.2315171120  0.311
2022 Vides EG, Adhikari A, Chiang CY, Lis P, Purlyte E, Limouse C, Shumate JL, Spinola-Lasso E, Dhekne HS, Alessi DR, Pfeffer SR. A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation. Elife. 11. PMID 36149401 DOI: 10.7554/eLife.79771  0.312
2022 Pfeffer SR. LRRK2 phosphorylation of Rab GTPases in Parkinson's disease. Febs Letters. PMID 36114007 DOI: 10.1002/1873-3468.14492  0.337
2021 Gomez RC, Vides EG, Pfeffer SR. Rab29 Fast Exchange Mutants: Characterization of a Challenging Rab GTPase. Methods in Molecular Biology (Clifton, N.J.). 2293: 19-25. PMID 34453707 DOI: 10.1007/978-1-0716-1346-7_2  0.357
2020 Saha P, Shumate JL, Caldwell JG, Elghobashi-Meinhardt N, Lu A, Zhang L, Olsson NE, Elias JE, Pfeffer SR. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. Elife. 9. PMID 32410728 DOI: 10.7554/Elife.57089  0.45
2020 Saha P, Shumate JL, Caldwell JG, Elghobashi-Meinhardt N, Lu A, Zhang L, Olsson NE, Elias JE, Pfeffer SR. Author response: Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins Elife. DOI: 10.7554/Elife.57089.Sa2  0.422
2020 Pfeffer SR. Decision letter: A non-linear system patterns Rab5 GTPase on the membrane Elife. DOI: 10.7554/Elife.54434.Sa1  0.332
2019 Berndsen K, Lis P, Yeshaw WM, Wawro PS, Nirujogi RS, Wightman M, Macartney T, Dorward M, Knebel A, Tonelli F, Pfeffer SR, Alessi DR. PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. Elife. 8. PMID 31663853 DOI: 10.7554/Elife.50416  0.426
2019 Gomez RC, Wawro P, Lis P, Alessi DR, Pfeffer SR. Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases. The Journal of Cell Biology. PMID 31624137 DOI: 10.1083/Jcb.201902184  0.434
2019 Pfeffer SR. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes. The Journal of Biological Chemistry. 294: 1706-1709. PMID 30710017 DOI: 10.1074/Jbc.Tm118.004165  0.334
2019 Berndsen K, Lis P, Yeshaw WM, Wawro PS, Nirujogi RS, Wightman M, Macartney T, Dorward M, Knebel A, Tonelli F, Pfeffer SR, Alessi DR. Author response: PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins Elife. DOI: 10.7554/Elife.50416.039  0.326
2018 Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR. Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs. Elife. 7. PMID 30556811 DOI: 10.7554/Elife.41460  0.357
2018 Pfeffer SR. LRRK2 and Rab GTPases. Biochemical Society Transactions. PMID 30467121 DOI: 10.1042/Bst20180470  0.424
2018 Dhekne HS, Yanatori I, Gomez RC, Tonelli F, Diez F, Schüle B, Steger M, Alessi DR, Pfeffer SR. A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. Elife. 7. PMID 30398148 DOI: 10.7554/Elife.40202  0.302
2017 Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR. Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. The Embo Journal. PMID 29212815 DOI: 10.15252/Embj.201798099  0.359
2017 Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. Elife. 6. PMID 29125462 DOI: 10.7554/Elife.31012  0.381
2017 Pfeffer SR. Rab GTPases: master regulators that establish the secretory and endocytic pathways. Molecular Biology of the Cell. 28: 712-715. PMID 28292916 DOI: 10.1091/Mbc.E16-10-0737  0.542
2016 Li J, Pfeffer SR. Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export. Elife. 5. PMID 27664420 DOI: 10.7554/Elife.21635  0.448
2016 Li X, Saha P, Li J, Blobel G, Pfeffer SR. Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27551080 DOI: 10.1073/Pnas.1611956113  0.408
2016 Pfeffer SR. Clues to NPC1-mediated cholesterol export from lysosomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27410046 DOI: 10.1073/Pnas.1608530113  0.49
2016 Johnson TA, Pfeffer SR. Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis. Molecular Biology of the Cell. PMID 27075173 DOI: 10.1091/Mbc.E16-03-0154  0.419
2016 Cheung PY, Pfeffer SR. Transport Vesicle Tethering at the Trans Golgi Network: Coiled Coil Proteins in Action. Frontiers in Cell and Developmental Biology. 4: 18. PMID 27014693 DOI: 10.3389/Fcell.2016.00018  0.523
2016 Li J, Pfeffer SR. Author response: Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export Elife. DOI: 10.7554/Elife.21635.013  0.388
2015 Cheung PP, Limouse C, Mabuchi H, Pfeffer SR. Protein flexibility is required for vesicle tethering at the Golgi. Elife. 4. PMID 26653856 DOI: 10.7554/Elife.12790  0.453
2015 Li J, Deffieu MS, Lee PL, Saha P, Pfeffer SR. Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26578804 DOI: 10.1073/Pnas.1520490112  0.782
2015 Lee PL, Ohlson MB, Pfeffer SR. Rab6 regulation of the kinesin family KIF1C motor domain contributes to Golgi tethering. Elife. 4. PMID 25821985 DOI: 10.7554/Elife.06029  0.793
2015 Nottingham RM, Pfeffer SR. Measuring Rab GTPase-activating protein (GAP) activity in live cells and extracts. Methods in Molecular Biology (Clifton, N.J.). 1298: 61-71. PMID 25800832 DOI: 10.1007/978-1-4939-2569-8_5  0.371
2015 Cheung PY, Pfeffer SR. Molecular and cellular characterization of GCC185: a tethering protein of the trans-Golgi network. Methods in Molecular Biology (Clifton, N.J.). 1270: 179-90. PMID 25702118 DOI: 10.1007/978-1-4939-2309-0_14  0.524
2015 Cheung PP, Limouse C, Mabuchi H, Pfeffer SR. Author response: Protein flexibility is required for vesicle tethering at the Golgi Elife. DOI: 10.7554/Elife.12790.017  0.411
2014 Lu A, Pfeffer SR. A CULLINary ride across the secretory pathway: more than just secretion. Trends in Cell Biology. 24: 389-99. PMID 24630736 DOI: 10.1016/J.Tcb.2014.02.001  0.359
2013 Pfeffer SR. A prize for membrane magic. Cell. 155: 1203-6. PMID 24315088 DOI: 10.1016/J.Cell.2013.11.014  0.472
2013 Pfeffer SR. Hopping rim to rim through the Golgi. Elife. 2: e00903. PMID 23795298 DOI: 10.7554/Elife.00903  0.424
2013 Pfeffer SR. Rab GTPase regulation of membrane identity. Current Opinion in Cell Biology. 25: 414-9. PMID 23639309 DOI: 10.1016/J.Ceb.2013.04.002  0.495
2013 Pfeffer SR. A nexus for receptor recycling. Nature Cell Biology. 15: 446-8. PMID 23636423 DOI: 10.1038/Ncb2751  0.402
2012 Pfeffer SR. Rab GTPase localization and Rab cascades in Golgi transport. Biochemical Society Transactions. 40: 1373-7. PMID 23176483 DOI: 10.1042/Bst20120168  0.568
2012 Pusapati GV, Luchetti G, Pfeffer SR. Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase. The Journal of Biological Chemistry. 287: 42129-37. PMID 23091056 DOI: 10.1074/Jbc.M112.414565  0.825
2012 Goueli BS, Powell MB, Finger EC, Pfeffer SR. TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 15787-92. PMID 23019362 DOI: 10.1073/Pnas.1204540109  0.819
2012 Pfeffer SR. Cargo carriers from the Golgi to the cell surface. The Embo Journal. 31: 3954-5. PMID 22940689 DOI: 10.1038/Emboj.2012.249  0.392
2012 van Rahden VA, Brand K, Najm J, Heeren J, Pfeffer SR, Braulke T, Kutsche K. The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module. Human Molecular Genetics. 21: 5019-38. PMID 22907655 DOI: 10.1093/Hmg/Dds343  0.471
2012 Nottingham RM, Pusapati GV, Ganley IG, Barr FA, Lambright DG, Pfeffer SR. RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36. The Journal of Biological Chemistry. 287: 22740-8. PMID 22637480 DOI: 10.1074/Jbc.M112.362558  0.857
2012 Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, et al. Ebola virus entry requires the host-programmed recognition of an intracellular receptor. The Embo Journal. 31: 1947-60. PMID 22395071 DOI: 10.1038/Emboj.2012.53  0.813
2012 Espinosa EJ, Pfeffer SR. Transport from late endosomes to the golgi: Rab9 gtpase Rab Gtpases and Membrane Trafficking. 144-154. DOI: 10.2174/978160805365011201010144  0.739
2011 Deffieu MS, Pfeffer SR. Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding. Proceedings of the National Academy of Sciences of the United States of America. 108: 18932-6. PMID 22065762 DOI: 10.1073/Pnas.1110439108  0.805
2011 Brown FC, Schindelhaim CH, Pfeffer SR. GCC185 plays independent roles in Golgi structure maintenance and AP-1-mediated vesicle tethering. The Journal of Cell Biology. 194: 779-87. PMID 21875948 DOI: 10.1083/Jcb.201104019  0.743
2011 Nottingham RM, Ganley IG, Barr FA, Lambright DG, Pfeffer SR. RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. The Journal of Biological Chemistry. 286: 33213-22. PMID 21808068 DOI: 10.1074/Jbc.M111.261115  0.758
2011 Pfeffer SR. Entry at the trans-face of the Golgi. Cold Spring Harbor Perspectives in Biology. 3. PMID 21421921 DOI: 10.1101/Cshperspect.A005272  0.524
2010 Brown FC, Pfeffer SR. An update on transport vesicle tethering. Molecular Membrane Biology. 27: 457-61. PMID 21067454 DOI: 10.3109/09687688.2010.501765  0.739
2010 Pfeffer SR. How the Golgi works: a cisternal progenitor model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19614-8. PMID 21045128 DOI: 10.1073/Pnas.1011016107  0.491
2010 Pfeffer SR. Recent advances in understanding Golgi biogenesis. F1000 Biology Reports. 2: 32. PMID 20625450 DOI: 10.3410/B2-32  0.362
2010 Pfeffer SR. Unconventional secretion by autophagosome exocytosis. The Journal of Cell Biology. 188: 451-2. PMID 20156968 DOI: 10.1083/Jcb.201001121  0.314
2010 Pfeffer SR. Two Rabs for exosome release. Nature Cell Biology. 12: 3-4. PMID 20027197 DOI: 10.1038/Ncb0110-3  0.394
2010 Pfeffer SR. How does your golgi go? Scientist. 24.  0.347
2009 Emr S, Glick BS, Linstedt AD, Lippincott-Schwartz J, Luini A, Malhotra V, Marsh BJ, Nakano A, Pfeffer SR, Rabouille C, Rothman JE, Warren G, Wieland FT. Journeys through the Golgi--taking stock in a new era. The Journal of Cell Biology. 187: 449-53. PMID 19948493 DOI: 10.1083/Jcb.200909011  0.809
2009 Pfeffer SR. Multiple routes of protein transport from endosomes to the trans Golgi network. Febs Letters. 583: 3811-6. PMID 19879268 DOI: 10.1016/J.Febslet.2009.10.075  0.493
2009 Nottingham RM, Pfeffer SR. Defining the boundaries: Rab GEFs and GAPs. Proceedings of the National Academy of Sciences of the United States of America. 106: 14185-6. PMID 19706500 DOI: 10.1073/Pnas.0907725106  0.556
2009 Espinosa EJ, Calero M, Sridevi K, Pfeffer SR. RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport. Cell. 137: 938-48. PMID 19490898 DOI: 10.1016/J.Cell.2009.03.043  0.854
2009 Pfeffer S. Suzanne Pfeffer: sorting through membrane trafficking. Interview by Caitlin Sedwick The Journal of Cell Biology. 185: 4-5. PMID 19349576  0.378
2009 Hayes GL, Brown FC, Haas AK, Nottingham RM, Barr FA, Pfeffer SR. Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi. Molecular Biology of the Cell. 20: 209-17. PMID 18946081 DOI: 10.1091/Mbc.E08-07-0740  0.828
2008 Hayes GL, Pfeffer SR. WHAMMing into the Golgi. Developmental Cell. 15: 171-2. PMID 18694552 DOI: 10.1016/J.Devcel.2008.07.011  0.812
2008 Nottingham RM, Pfeffer SR. Team effort by TRAPP forces a nucleotide fumble. Cell. 133: 1141-3. PMID 18585348 DOI: 10.1016/J.Cell.2008.06.012  0.424
2008 Burguete AS, Fenn TD, Brunger AT, Pfeffer SR. Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell. 132: 286-98. PMID 18243103 DOI: 10.1016/J.Cell.2007.11.048  0.533
2008 Ganley IG, Espinosa E, Pfeffer SR. A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. The Journal of Cell Biology. 180: 159-72. PMID 18195106 DOI: 10.1083/Jcb.200707136  0.85
2007 Pfeffer S. Microbiology: Pathogen drop-kick Nature. 450: 361-362. PMID 18004371 DOI: 10.1038/450361A  0.385
2007 Sklan EH, Serrano RL, Einav S, Pfeffer SR, Lambright DG, Glenn JS. TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication. The Journal of Biological Chemistry. 282: 36354-61. PMID 17901050 DOI: 10.1074/Jbc.M705221200  0.691
2007 Pfeffer SR. Unsolved mysteries in membrane traffic. Annual Review of Biochemistry. 76: 629-45. PMID 17263661 DOI: 10.1146/Annurev.Biochem.76.061705.130002  0.444
2006 Reddy JV, Ganley IG, Pfeffer SR. Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling. Plos One. 1: e19. PMID 17183645 DOI: 10.1371/Journal.Pone.0000019  0.637
2006 Reddy JV, Burguete AS, Sridevi K, Ganley IG, Nottingham RM, Pfeffer SR. A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling. Molecular Biology of the Cell. 17: 4353-63. PMID 16885419 DOI: 10.1091/Mbc.E06-02-0153  0.781
2006 Aivazian D, Serrano RL, Pfeffer S. TIP47 is a key effector for Rab9 localization Journal of Cell Biology. 173: 917-926. PMID 16769818 DOI: 10.1083/Jcb.200510010  0.823
2006 Ganley IG, Pfeffer SR. Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells. The Journal of Biological Chemistry. 281: 17890-9. PMID 16644737 DOI: 10.1074/Jbc.M601679200  0.692
2005 Burguete AS, Harbury PB, Pfeffer SR. Misincorporation proton-alkyl exchange (MPAX): engineering cysteine probes into proteins. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit26.1. PMID 18429287 DOI: 10.1002/0471140864.Ps2601S42  0.433
2005 Burguete AS, Sivars U, Pfeffer S. Purification and analysis of TIP47 function in Rab9-dependent mannose 6-phosphate receptor trafficking Methods in Enzymology. 403: 357-366. PMID 16473602 DOI: 10.1016/S0076-6879(05)03031-4  0.851
2005 Sivars U, Aivazian D, Pfeffer S. Purification and properties of Yip3/PRA1 as a Rab GDI displacement factor Methods in Enzymology. 403: 348-356. PMID 16473601 DOI: 10.1016/S0076-6879(05)03030-2  0.816
2005 Pfeffer S. Filling the Rab GAP Nature Cell Biology. 7: 856-857. PMID 16136184 DOI: 10.1038/Ncb0905-856  0.369
2005 Pfeffer S. A model for Rab GTPase localization Biochemical Society Transactions. 33: 627-630. PMID 16042559 DOI: 10.1042/Bst0330627  0.481
2005 Pfeffer SR. Structural clues to Rab GTPase functional diversity. The Journal of Biological Chemistry. 280: 15485-8. PMID 15746102 DOI: 10.1074/Jbc.R500003200  0.45
2004 Burguete AS, Harbury PB, Pfeffer SR. In vitro selection and prediction of TIP47 protein-interaction interfaces. Nature Methods. 1: 55-60. PMID 15782153 DOI: 10.1038/Nmeth702  0.481
2004 Pfeffer S, Aivazian D. Targeting Rab GTPases to distinct membrane compartments Nature Reviews Molecular Cell Biology. 5: 886-896. PMID 15520808 DOI: 10.1038/Nrm1500  0.845
2004 Ganley IG, Carroll K, Bittova L, Pfeffer S. Rab9 GTPase regulates late endosome size and requires effector interaction for its stability Molecular Biology of the Cell. 15: 5420-5430. PMID 15456905 DOI: 10.1091/Mbc.E04-08-0747  0.836
2003 Sivars U, Aivazian D, Pfeffer SR. Yip3 catalyses the dissociation of endosomal Rab-GDI complexes. Nature. 425: 856-9. PMID 14574414 DOI: 10.1038/Nature02057  0.842
2003 Pfeffer S. Membrane domains in the secretory and endocytic pathways Cell. 112: 507-517. PMID 12600314 DOI: 10.1016/S0092-8674(03)00118-1  0.511
2003 Sincock PM, Ganley IG, Krise JP, Diederichs S, Sivars U, O'Connor B, Ding L, Pfeffer SR. Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport. Traffic (Copenhagen, Denmark). 4: 18-25. PMID 12535272 DOI: 10.1034/J.1600-0854.2003.40104.X  0.803
2002 Hanna J, Carroll K, Pfeffer SR. Identification of residues in TIP47 essential for Rab9 binding. Proceedings of the National Academy of Sciences of the United States of America. 99: 7450-4. PMID 12032303 DOI: 10.1073/Pnas.112198799  0.702
2002 Barbero P, Bittova L, Pfeffer SR. Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells. The Journal of Cell Biology. 156: 511-8. PMID 11827983 DOI: 10.1083/Jcb.200109030  0.856
2001 Pfeffer SR. Constructing a Golgi complex. The Journal of Cell Biology. 155: 873-5. PMID 11739400 DOI: 10.1083/Jcb.200109095  0.372
2001 Pfeffer SR. Rab GTPases: specifying and deciphering organelle identity and function. Trends in Cell Biology. 11: 487-91. PMID 11719054 DOI: 10.1016/S0962-8924(01)02147-X  0.507
2001 Pfeffer S. Vesicle tethering factors united Molecular Cell. 8: 729-730. PMID 11684005 DOI: 10.1016/S1097-2765(01)00371-9  0.414
2001 Carroll KS, Hanna J, Simon I, Krise J, Barbero P, Pfeffer SR. Role of Rab9 GTPase in facilitating receptor recruitment by TIP47. Science (New York, N.Y.). 292: 1373-6. PMID 11359012 DOI: 10.1126/Science.1056791  0.835
2001 Pfeffer SR. Caveolae on the move. Nature Cell Biology. 3: E108-10. PMID 11331891 DOI: 10.1038/35074625  0.389
2001 Barbero P, Buell E, Zulley S, Pfeffer SR. TIP47 is not a component of lipid droplets. The Journal of Biological Chemistry. 276: 24348-51. PMID 11313361 DOI: 10.1074/Jbc.M102468200  0.696
2001 Pfeffer SR. Membrane transport: retromer to the rescue. Current Biology : Cb. 11: R109-11. PMID 11231171 DOI: 10.1016/S0960-9822(01)00042-2  0.542
2000 Orsel JG, Sincock PM, Krise JP, Pfeffer SR. Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 9047-51. PMID 10908666 DOI: 10.1073/Pnas.160251397  0.819
2000 Krise JP, Sincock PM, Orsel JG, Pfeffer SR. Quantitative analysis of TIP47-receptor cytoplasmic domain interactions: implications for endosome-to-trans Golgi network trafficking. The Journal of Biological Chemistry. 275: 25188-93. PMID 10829017 DOI: 10.1074/Jbc.M001138200  0.827
1999 Pfeffer SR. Motivating endosome motility. Nature Cell Biology. 1: E145-7. PMID 10559973 DOI: 10.1038/14097  0.439
1999 Pfeffer SR. Transport-vesicle targeting: tethers before SNAREs. Nature Cell Biology. 1: E17-22. PMID 10559876 DOI: 10.1038/8967  0.501
1999 Waters MG, Pfeffer SR. Membrane tethering in intracellular transport. Current Opinion in Cell Biology. 11: 453-9. PMID 10449330 DOI: 10.1016/S0955-0674(99)80065-9  0.745
1999 Itin C, Ulitzur N, Mühlbauer B, Pfeffer SR. Mapmodulin, cytoplasmic dynein, and microtubules enhance the transport of mannose 6-phosphate receptors from endosomes to the trans-golgi network. Molecular Biology of the Cell. 10: 2191-7. PMID 10397758 DOI: 10.1091/Mbc.10.7.2191  0.828
1998 Schimmöller F, Díaz E, Mühlbauer B, Pfeffer SR. Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. Gene. 216: 311-8. PMID 9729438 DOI: 10.1016/S0378-1119(98)00349-7  0.521
1998 Schimmöller F, Simon I, Pfeffer SR. Rab GTPases, directors of vesicle docking. The Journal of Biological Chemistry. 273: 22161-4. PMID 9712825 DOI: 10.1074/Jbc.273.35.22161  0.751
1998 Díaz E, Pfeffer SR. TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking. Cell. 93: 433-43. PMID 9590177 DOI: 10.1016/S0092-8674(00)81171-X  0.55
1997 Ulitzur N, Rancaño C, Pfeffer SR. Biochemical characterization of mapmodulin, a protein that binds microtubule-associated proteins. The Journal of Biological Chemistry. 272: 30577-82. PMID 9374554 DOI: 10.1074/Jbc.272.48.30577  0.807
1997 Itin C, Rancaño C, Nakajima Y, Pfeffer SR. A novel assay reveals a role for soluble N-ethylmaleimide-sensitive fusion attachment protein in mannose 6-phosphate receptor transport from endosomes to the trans Golgi network. The Journal of Biological Chemistry. 272: 27737-44. PMID 9346916 DOI: 10.1074/Jbc.272.44.27737  0.804
1997 Nakajima Y, Pfeffer SR. Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network. Molecular Biology of the Cell. 8: 577-82. PMID 9247639 DOI: 10.1091/Mbc.8.4.577  0.42
1997 Díaz E, Schimmöller F, Pfeffer SR. A novel Rab9 effector required for endosome-to-TGN transport. The Journal of Cell Biology. 138: 283-90. PMID 9230071 DOI: 10.1083/Jcb.138.2.283  0.539
1997 Schimmöller F, Itin C, Pfeffer S. Vesicle traffic: Get your coat! Current Biology. 7: R235-R237. PMID 9162499 DOI: 10.1016/S0960-9822(06)00109-6  0.827
1997 Ulitzur N, Humbert M, Pfeffer SR. Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules. Proceedings of the National Academy of Sciences of the United States of America. 94: 5084-9. PMID 9144194 DOI: 10.1073/Pnas.94.10.5084  0.789
1997 Dirac-Svejstrup AB, Sumizawa T, Pfeffer SR. Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI. The Embo Journal. 16: 465-72. PMID 9034329 DOI: 10.1093/Emboj/16.3.465  0.523
1996 Pfeffer SR. Transport vesicle docking: SNAREs and associates. Annual Review of Cell and Developmental Biology. 12: 441-61. PMID 8970734 DOI: 10.1146/Annurev.Cellbio.12.1.441  0.548
1995 Pfeffer SR, Soldati T, Geissler H, Rancaño C, Dirac-Svejstrup B. Selective membrane recruitment of Rab GTPases. Cold Spring Harbor Symposia On Quantitative Biology. 60: 221-7. PMID 8824394 DOI: 10.1101/Sqb.1995.060.01.025  0.793
1995 Soldati T, Shapiro AD, Pfeffer SR. Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranes. Methods in Enzymology. 257: 253-9. PMID 8583928 DOI: 10.1016/S0076-6879(95)57030-6  0.759
1995 Riederer MA, Soldati T, Dirac-Svejstrup AB, Pfeffer SR. Expression of Rab9 protein in Escherichia coli: purification and isoprenylation in vitro. Methods in Enzymology. 257: 15-21. PMID 8583917 DOI: 10.1016/S0076-6879(95)57005-5  0.714
1995 Shapiro AD, Pfeffer SR. Quantitative analysis of the interactions between prenyl Rab9, GDP dissociation inhibitor-alpha, and guanine nucleotides. The Journal of Biological Chemistry. 270: 11085-90. PMID 7744738 DOI: 10.1074/Jbc.270.19.11085  0.352
1995 Pfeffer SR, Dirac-Svejstrup AB, Soldati T. Rab GDP dissociation inhibitor: putting rab GTPases in the right place. The Journal of Biological Chemistry. 270: 17057-9. PMID 7615494 DOI: 10.1074/Jbc.270.29.17057  0.587
1995 Soldati T, Rancaño C, Geissler H, Pfeffer SR. Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes. The Journal of Biological Chemistry. 270: 25541-8. PMID 7592724 DOI: 10.1074/Jbc.270.43.25541  0.827
1994 Dirac-Svejstrup AB, Soldati T, Shapiro AD, Pfeffer SR. Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitment. The Journal of Biological Chemistry. 269: 15427-30. PMID 8195183  0.503
1994 Soldati T, Shapiro AD, Svejstrup AB, Pfeffer SR. Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange. Nature. 369: 76-8. PMID 8164745 DOI: 10.1038/369076A0  0.763
1994 Dintzis SM, Velculescu VE, Pfeffer SR. Receptor extracellular domains may contain trafficking information. Studies of the 300-kDa mannose 6-phosphate receptor. The Journal of Biological Chemistry. 269: 12159-66. PMID 8163521  0.312
1994 Pfeffer SR. Rab GTPases: master regulators of membrane trafficking. Current Opinion in Cell Biology. 6: 522-6. PMID 7986528 DOI: 10.1016/0955-0674(94)90071-X  0.568
1994 Riederer MA, Soldati T, Shapiro AD, Lin J, Pfeffer SR. Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. The Journal of Cell Biology. 125: 573-82. PMID 7909812 DOI: 10.1083/Jcb.125.3.573  0.78
1993 Lombardi D, Soldati T, Riederer MA, Goda Y, Zerial M, Pfeffer SR. Rab9 functions in transport between late endosomes and the trans Golgi network. The Embo Journal. 12: 677-82. PMID 8440258 DOI: 10.1002/J.1460-2075.1993.Tb05701.X  0.813
1993 Soldati T, Riederer MA, Pfeffer SR. Rab GDI: A solubilizing and recycling factor for rab9 protein Molecular Biology of the Cell. 4: 425-434. PMID 8389620 DOI: 10.1091/Mbc.4.4.425  0.814
1992 Corthesy-Theulaz I, Pfeffer SR. [16] Microtubule-mediated Golgi capture by semiintact Chinese hamster ovary cells Methods in Enzymology. 219: 159-165. PMID 1487989 DOI: 10.1016/0076-6879(92)19018-2  0.476
1992 Goda Y, Soldati T, Pfeffer SR. Transport from late endosomes to trans-Golgi network in semiintact cell extracts. Methods in Enzymology. 219: 153-9. PMID 1487988 DOI: 10.1016/0076-6879(92)19017-Z  0.705
1992 Corthésy-Theulaz I, Pauloin A, Pfeffer SR. Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex Journal of Cell Biology. 118: 1333-1345. PMID 1387874 DOI: 10.1083/Jcb.118.6.1333  0.454
1992 Pfeffer SR. GTP-binding proteins in intracellular transport Trends in Cell Biology. 2: 41-46. DOI: 10.1016/0962-8924(92)90161-F  0.568
1991 Goda Y, Pfeffer SR. Identification of a novel, N-ethylmaleimide-sensitive cytosolic factor required for vesicular transport from endosomes to the trans-Golgi network in vitro. The Journal of Cell Biology. 112: 823-31. PMID 1999460 DOI: 10.1083/Jcb.112.5.823  0.507
1991 Pfeffer SR. Targeting of proteins to the lysosome Current Topics in Microbiology and Immunology. 170: 43-65. PMID 1662126 DOI: 10.1007/978-3-642-76389-2_2  0.355
1990 Chege NW, Pfeffer SR. Compartmentation of the Golgi complex: Brefeldin-A distinguishes trans-Golgi cisternae from the trans-Golgi network Journal of Cell Biology. 111: 893-899. PMID 2167898 DOI: 10.1083/Jcb.111.3.893  0.432
1990 Draper RK, Goda Y, Brodsky FM, Pfeffer SR. Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitro. Science (New York, N.Y.). 248: 1539-41. PMID 2163108 DOI: 10.1126/Science.2163108  0.42
1990 Dintzis SM, Pfeffer SR. The mannose 6-phosphate receptor cytoplasmic domain is not sufficient to alter the cellular distribution of a chimeric EGF receptor Embo Journal. 9: 77-84. PMID 2153081 DOI: 10.1002/J.1460-2075.1990.Tb08082.X  0.429
1990 Pfeffer SR. A budding and fusing journey through the secretory pathway New Biologist. 2: 430-434. PMID 2126957  0.409
1989 Goda Y, Pfeffer SR. Cell-free systems to study vesicular transport along the secretory and endocytic pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 2488-95. PMID 2680705 DOI: 10.1096/Fasebj.3.13.2680705  0.536
1988 Pfeffer SR. Mannose 6-phosphate receptors and their role in targeting proteins to lysosomes The Journal of Membrane Biology. 103: 7-16. PMID 2972840 DOI: 10.1007/Bf01871928  0.397
1988 Goda Y, Pfeffer SR. Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitro. Cell. 55: 309-20. PMID 2971452 DOI: 10.1016/0092-8674(88)90054-2  0.423
1988 Macdonald RG, Pfeffer SR, Coussens L, Tepper MA, Brocklebank CM, Mole JE, Anderson JK, Chen E, Czech MP, Ullrich A. A single receptor binds both insulin-like growth factor II and mannose-6-phosphate Science. 239: 1134-1137. PMID 2964083 DOI: 10.1126/Science.2964083  0.303
1987 Pfeffer SR, Rothman JE. Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annual Review of Biochemistry. 56: 829-52. PMID 3304148 DOI: 10.1146/Annurev.Bi.56.070187.004145  0.642
1987 Pfeffer SR. The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis Journal of Cell Biology. 105: 229-234. PMID 3038925 DOI: 10.1083/Jcb.105.1.229  0.38
1986 Dunphy WG, Pfeffer SR, Clary DO, Wattenberg BW, Glick BS, Rothman JE. Yeast and mammals utilize similar cytosolic components to drive protein transport through the Golgi complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 1622-6. PMID 3513182 DOI: 10.1073/Pnas.83.6.1622  0.823
1986 Pâquet MR, Pfeffer SR, Burczak JD, Glick BS, Rothman JE. Components responsible for transport between successive Golgi cisternae are highly conserved in evolution. The Journal of Biological Chemistry. 261: 4367-70. PMID 3007452  0.675
1986 Redman CM, Avellino G, Pfeffer SR, Mukherjee TK, Nichols M, Rubinstein P, Marsh WL. Kell blood group antigens are part of a 93,000-dalton red cell membrane protein. The Journal of Biological Chemistry. 261: 9521-5. PMID 2424912  0.302
1985 Pfeffer SR, Kelly RB. The subpopulation of brain coated vesicles that carries synaptic vesicle proteins contains two unique polypeptides. Cell. 40: 949-57. PMID 2859122 DOI: 10.1016/0092-8674(85)90355-1  0.544
1983 Kelly RB, Buckley KM, Burgess TL, Carlson SS, Caroni P, Hooper JE, Katzen A, Moore HP, Pfeffer SR, Schroer TA. Membrane traffic in neurons and peptide-secreting cells. Cold Spring Harbor Symposia On Quantitative Biology. 48: 697-705. PMID 6327173 DOI: 10.1101/Sqb.1983.048.01.073  0.763
1983 Pfeffer SR, Drubin DG, Kelly RB. Identification of three coated vesicle components as alpha- and beta-tubulin linked to a phosphorylated 50,000-dalton polypeptide. The Journal of Cell Biology. 97: 40-7. PMID 6134738  0.54
1982 Pfeffer SR, Swislocki NI. Role of peroxidation in erythrocyte aging Mechanisms of Ageing and Development. 18: 355-367. PMID 6896544 DOI: 10.1016/0047-6374(82)90038-0  0.341
1981 Pfeffer SR, Kelly RB. Identification of minor components of coated vesicles by use of permeation chromatography. The Journal of Cell Biology. 91: 385-91. PMID 7309787  0.546
1981 Pfeffer SR, Redman CM. Biosynthesis of mouse erythrocyte membrane proteins by friend erythroleukemia cells Bba - Biomembranes. 641: 254-263. PMID 6938247 DOI: 10.1016/0005-2736(81)90589-7  0.338
1977 Pfeffer SR, Stahl SJ, Chamberlin MJ. Binding of Escherichia coli RNA polymerase to T7 DNA. Displacement of holoenzyme from promoter complexes by heparin. The Journal of Biological Chemistry. 252: 5403-7. PMID 328501  0.506
Low-probability matches (unlikely to be authored by this person)
1991 Pfeffer SR. Mannose-6-phosphate receptors and their role in protein sorting along the pathway to lysosomes Cell Biophysics. 19: 131-140. PMID 1726883 DOI: 10.1007/BF02989886  0.296
2017 Li J, Lee PL, Pfeffer SR. Quantitative Measurement of Cholesterol in Cell Populations Using Flow Cytometry and Fluorescent Perfringolysin O. Methods in Molecular Biology (Clifton, N.J.). 1583: 85-95. PMID 28205169 DOI: 10.1007/978-1-4939-6875-6_8  0.295
2010 Pfeffer SR, Novick PJ. Membrane traffic. Current Opinion in Cell Biology. 22: 419-21. PMID 20566276 DOI: 10.1016/j.ceb.2010.06.001  0.294
2019 Pfeffer SR, Lambright D. Decision letter: Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding Elife. DOI: 10.7554/Elife.46302.028  0.294
1988 Pfeffer SR, Goda Y, Chege NW. Intracellular transport of the mannose-6-phosphate receptor. Progress in Clinical and Biological Research. 270: 365-75. PMID 2970646  0.293
2016 Pfeffer SR. Lipoprotein secretion: It takes two to TANGO. The Journal of Cell Biology. PMID 27138249 DOI: 10.1083/Jcb.201604084  0.292
2015 Lee PL, Ohlson MB, Pfeffer SR. Author response: The Rab6-regulated KIF1C kinesin motor domain contributes to Golgi organization Elife. DOI: 10.7554/Elife.06029.022  0.292
2009 Lee PL, Kohler JJ, Pfeffer SR. Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis. Glycobiology. 19: 655-64. PMID 19261593 DOI: 10.1093/Glycob/Cwp035  0.29
1978 Swislocki NI, Tierney J, Zinberg J, Pfeffer SR. Reduced rat erythrocyte lifetimes and elevated activities of membrane adenylate cyclase and protein kinase after glucosulfone treatment [proceedings] Advances in Experimental Medicine and Biology. 97: 301-305. PMID 645482  0.287
1976 Pfeffer SR, Swislocki NI. Age-related decline in the activitities of erythrocyte membrane adenylate cyclase and protein kinase Archives of Biochemistry and Biophysics. 177: 117-122. PMID 187118 DOI: 10.1016/0003-9861(76)90421-5  0.287
2021 Dhekne HS, Yanatori I, Vides EG, Sobu Y, Diez F, Tonelli F, Pfeffer SR. LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade. Life Science Alliance. 4. PMID 33727250 DOI: 10.26508/lsa.202101050  0.283
2013 Lu A, Pfeffer SR. Golgi-associated RhoBTB3 targets cyclin E for ubiquitylation and promotes cell cycle progression. The Journal of Cell Biology. 203: 233-50. PMID 24145166 DOI: 10.1083/Jcb.201305158  0.278
2019 Pfeffer SR. Decision letter: Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes Elife. DOI: 10.7554/Elife.47544.030  0.272
2023 Pal P, Taylor M, Lam PY, Tonelli F, Hecht CA, Lis P, Nirujogi RS, Phung TK, Yeshaw WM, Jaimon E, Fasimoye R, Dickie EA, Wightman M, Macartney T, Pfeffer SR, et al. Parkinson's VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B. Science Advances. 9: eadj1205. PMID 38091401 DOI: 10.1126/sciadv.adj1205  0.27
2023 Dhekne HS, Tonelli F, Yeshaw WM, Chiang CY, Limouse C, Jaimon E, Purlyte E, Alessi DR, Pfeffer SR. Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson's disease-linked LRRK2 kinase. Elife. 12. PMID 37874635 DOI: 10.7554/eLife.87098  0.266
2017 Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M. Author response: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis Elife. DOI: 10.7554/Elife.31012.018  0.262
1985 Pfeffer S, Ullrich A. Epidermal growth factor. Is the precursor a receptor? Nature. 313: 184. PMID 3871505 DOI: 10.1038/313184A0  0.256
2019 Pfeffer SR, Maxfield FR. Decision letter: Intracellular cholesterol trafficking is dependent upon NPC2 interaction with lysobisphosphatidic acid Elife. DOI: 10.7554/Elife.50832.029  0.255
1999 Johnson LR, McCormack SA, Yang CH, Pfeffer SR, Pfeffer LM. EGF induces nuclear translocation of STAT2 without tyrosine phosphorylation in intestinal epithelial cells. The American Journal of Physiology. 276: C419-25. PMID 9950769 DOI: 10.1152/Ajpcell.1999.276.2.C419  0.254
1993 Shapiro AD, Riederer MA, Pfeffer SR. Biochemical analysis of rab9, a ras-like GTPase involved in protein transport from late endosomes to the trans golgi network Journal of Biological Chemistry. 268: 6925-6931. PMID 8463223  0.254
2021 Sobu Y, Wawro PS, Dhekne HS, Yeshaw WM, Pfeffer SR. Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33653948 DOI: 10.1073/pnas.2005894118  0.252
2014 Nottingham RM, Pfeffer SR. Mutant enzymes challenge all assumptions. Elife. 3: e02171. PMID 24520166 DOI: 10.7554/Elife.02171  0.245
1986 Pfeffer SR, Huima T, Redman CM. Biosynthesis of spectrin and its assembly into the cytoskeletal system of Friend erythroleukemia cells Journal of Cell Biology. 103: 103-113. PMID 3459731  0.242
2008 Yang CH, Murti A, Pfeffer SR, Fan M, Du Z, Pfeffer LM. The role of TRAF2 binding to the type I interferon receptor in alternative NF kappaB activation and antiviral response. The Journal of Biological Chemistry. 283: 14309-16. PMID 18362156 DOI: 10.1074/jbc.M708895200  0.241
2022 Lu A, Hsieh F, Sharma BR, Vaughn SR, Enrich C, Pfeffer SR. CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export. The Journal of Cell Biology. 221. PMID 34936700 DOI: 10.1083/jcb.202105060  0.213
1994 Pfeffer SR. Clues to brain function from bakers' yeast. Proceedings of the National Academy of Sciences of the United States of America. 91: 1987-8. PMID 8134336 DOI: 10.1073/Pnas.91.6.1987  0.213
2019 Pfeffer SR, Prinz WA. Decision letter: A critical role of VMP1 in lipoprotein secretion Elife. DOI: 10.7554/Elife.48834.024  0.211
2018 Pfeffer SR. Decision letter: A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation Elife. DOI: 10.7554/Elife.41768.025  0.211
2018 Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR. Author response: Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs Elife. DOI: 10.7554/Elife.41460.028  0.207
2018 Dhekne HS, Yanatori I, Gomez RC, Tonelli F, Diez F, Schüle B, Steger M, Alessi DR, Pfeffer SR. Author response: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain Elife. DOI: 10.7554/Elife.40202.019  0.199
2008 Chuan HY, Murti A, Pfeffer SR, Fan M, Du Z, Pfeffer LM. The role of TRAF2 binding to the type I interferon receptor in alternative NFκB activation and antiviral response (Journal of Biological Chemistry (2008) 283, (14309-14316)) Journal of Biological Chemistry. 283: 36752.  0.188
2019 Pfeffer SR, Alessi DR. Decision letter: Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72 Elife. DOI: 10.7554/Elife.48363.021  0.179
2006 Haynes L, Pfeffer S, Boss JM, Kavathas P, Kuchroo V. Lab management: insights for the new investigator. Nature Immunology. 7: 895-7. PMID 16924248 DOI: 10.1038/Ni0906-895  0.179
2000 Pfeffer LM, Yang CH, Pfeffer SR, Murti A, McCormack SA, Johnson LR. Inhibition of ornithine decarboxylase induces STAT3 tyrosine phosphorylation and DNA binding in IEC-6 cells. American Journal of Physiology. Cell Physiology. 278: C331-5. PMID 10666028 DOI: 10.1152/Ajpcell.2000.278.2.C331  0.177
1997 Pfeffer LM, Basu L, Pfeffer SR, Yang CH, Murti A, Russell-Harde D, Croze E. The short form of the interferon alpha/beta receptor chain 2 acts as a dominant negative for type I interferon action. The Journal of Biological Chemistry. 272: 11002-5. PMID 9110990 DOI: 10.1074/jbc.272.17.11002  0.176
1990 Pfeffer SR. Protein Transfer and Organelle Biogenesis.Rathindra C. Das , Phillips W. Robbins The Quarterly Review of Biology. 65: 76-76. DOI: 10.1086/416617  0.171
1997 Pfeffer LM, Mullersman JE, Pfeffer SR, Murti A, Shi W, Yang CH. STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor. Science (New York, N.Y.). 276: 1418-20. PMID 9162009 DOI: 10.1126/science.276.5317.1418  0.166
2000 Yang CH, Murti A, Pfeffer SR, Basu L, Kim JG, Pfeffer LM. IFNalpha/beta promotes cell survival by activating NF-kappa B. Proceedings of the National Academy of Sciences of the United States of America. 97: 13631-6. PMID 11095741 DOI: 10.1073/pnas.250477397  0.134
1984 Pfeffer SR, Redman CM. Biosynthesis of spectrin by friend erythroleukemia cells Federation Proceedings. 43: no. 1738.  0.127
2024 Alessi DR, Pfeffer SR. Leucine-Rich Repeat Kinases. Annual Review of Biochemistry. PMID 38621236 DOI: 10.1146/annurev-biochem-030122-051144  0.12
2007 Yang CH, Wei L, Pfeffer SR, Du Z, Murti A, Valentine WJ, Zheng Y, Pfeffer LM. Identification of CXCL11 as a STAT3-dependent gene induced by IFN. Journal of Immunology (Baltimore, Md. : 1950). 178: 986-92. PMID 17202361 DOI: 10.4049/Jimmunol.178.2.986  0.112
2014 Quackenbush JF, Cassidy PB, Pfeffer LM, Boucher KM, Hawkes JE, Pfeffer SR, Kopelovich L, Leachman SA. Isolation of circulating microRNAs from microvesicles found in human plasma. Methods in Molecular Biology (Clifton, N.J.). 1102: 641-53. PMID 24259003 DOI: 10.1007/978-1-62703-727-3_34  0.107
2001 Yang CH, Murti A, Pfeffer SR, Kim JG, Donner DB, Pfeffer LM. Interferon alpha /beta promotes cell survival by activating nuclear factor kappa B through phosphatidylinositol 3-kinase and Akt. The Journal of Biological Chemistry. 276: 13756-61. PMID 11278812 DOI: 10.1074/jbc.M011006200  0.1
2021 Khan SS, Sobu Y, Dhekne HS, Tonelli F, Berndsen K, Alessi DR, Pfeffer SR. Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain. Elife. 10. PMID 34658337 DOI: 10.7554/eLife.67900  0.096
2007 Du Z, Wei L, Murti A, Pfeffer SR, Fan M, Yang CH, Pfeffer LM. Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. Journal of Cellular Biochemistry. 102: 1087-94. PMID 17910035 DOI: 10.1002/Jcb.21535  0.095
2000 Nanus DM, Geng Y, Shen R, Lai HK, Pfeffer SR, Pfeffer LM. Interaction of retinoic acid and interferon in renal cancer cell lines. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 20: 787-94. PMID 11032398 DOI: 10.1089/10799900050151058  0.085
2012 Li K, Li NL, Wei D, Pfeffer SR, Fan M, Pfeffer LM. Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates. Hepatology (Baltimore, Md.). 55: 666-75. PMID 22030901 DOI: 10.1002/hep.24763  0.081
2024 Khan SS, Jaimon E, Lin YE, Nikoloff J, Tonelli F, Alessi DR, Pfeffer SR. Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. Biorxiv : the Preprint Server For Biology. PMID 38293195 DOI: 10.1101/2024.01.15.575737  0.078
2019 Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR. Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. The Embo Journal. 38. PMID 30647193 DOI: 10.15252/embj.2018101237  0.078
2014 Yang CH, Yue J, Pfeffer SR, Fan M, Paulus E, Hosni-Ahmed A, Sims M, Qayyum S, Davidoff AM, Handorf CR, Pfeffer LM. MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3). The Journal of Biological Chemistry. 289: 25079-87. PMID 25059666 DOI: 10.1074/jbc.M114.593863  0.076
1999 Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 401: 82-5. PMID 10485710 DOI: 10.1038/43466  0.074
2004 Pfeffer LM, Kim JG, Pfeffer SR, Carrigan DJ, Baker DP, Wei L, Homayouni R. Role of nuclear factor-kappaB in the antiviral action of interferon and interferon-regulated gene expression. The Journal of Biological Chemistry. 279: 31304-11. PMID 15131130 DOI: 10.1074/jbc.M308975200  0.073
2011 Janjetovic Z, Brozyna AA, Tuckey RC, Kim TK, Nguyen MN, Jozwicki W, Pfeffer SR, Pfeffer LM, Slominski AT. High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives. British Journal of Cancer. 105: 1874-84. PMID 22095230 DOI: 10.1038/Bjc.2011.458  0.066
2015 Yang CH, Pfeffer SR, Sims M, Yue J, Wang Y, Linga VG, Paulus E, Davidoff AM, Pfeffer LM. The oncogenic microRNA-21 inhibits the tumor suppressive activity of FBXO11 to promote tumorigenesis. The Journal of Biological Chemistry. 290: 6037-46. PMID 25589783 DOI: 10.1074/jbc.M114.632125  0.065
2013 Fan M, Pfeffer SR, Lynch HT, Cassidy P, Leachman S, Pfeffer LM, Kopelovich L. Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention. Oncotarget. 4: 128-41. PMID 23371019 DOI: 10.18632/Oncotarget.786  0.063
2015 Yang CH, Li K, Pfeffer SR, Pfeffer LM. The Type I IFN-Induced miRNA, miR-21. Pharmaceuticals (Basel, Switzerland). 8: 836-847. PMID 26610525 DOI: 10.3390/ph8040836  0.056
2015 Patil SA, Pfeffer SR, Seibel WL, Pfeffer LM, Miller DD. Identification of imidazoquinoline derivatives as potent antiglioma agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 11: 400-6. PMID 25219925 DOI: 10.2174/1573406410666140914162701  0.048
2011 Yang CH, Yue J, Pfeffer SR, Handorf CR, Pfeffer LM. MicroRNA miR-21 regulates the metastatic behavior of B16 melanoma cells. The Journal of Biological Chemistry. 286: 39172-8. PMID 21940630 DOI: 10.1074/jbc.M111.285098  0.044
1994 Auer M, Owens SR, Pfeffer S, Kallen J, Wasserbauer E, Aschauer H, Ehn G, Rot A, Besemer J, Lam C. Elucidation of structure function relationships in the IL-8 family by X-ray crystallography. Advances in Experimental Medicine and Biology. 351: 171-82. PMID 7942294 DOI: 10.1007/978-1-4615-2952-1_18  0.033
2015 Pfeffer SR, Yang CH, Pfeffer LM. The Role of miR-21 in Cancer. Drug Development Research. PMID 26082192 DOI: 10.1002/ddr.21257  0.028
2014 Pfeffer LM, Li K, Fleckenstein JF, Marion TN, Diament J, Yang CH, Pfeffer SR, Fan M, Handorf E, Handorf CR. An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. Plos One. 9: e104202. PMID 25111807 DOI: 10.1371/Journal.Pone.0104202  0.024
1999 Nagata S, Pfeffer SR. Biddable death Nature Cell Biology. 1: E143-E147. PMID 10559972  0.01
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