Vadim Cherezov - Publications

Affiliations: 
Integrative Structural and Computational Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Luginina A, Maslov I, Khorn P, Volkov O, Khnykin A, Kuzmichev P, Shevtsov M, Belousov A, Kapranov I, Dashevskii D, Kornilov D, Bestsennaia E, Hofkens J, Hendrix J, Gensch T, ... Cherezov V, et al. Functional GPCR Expression in Eukaryotic LEXSY System. Journal of Molecular Biology. 435: 168310. PMID 37806553 DOI: 10.1016/j.jmb.2023.168310  0.34
2023 Luginina A, Gusach A, Lyapina E, Khorn P, Safronova N, Shevtsov M, Dmitirieva D, Dashevskii D, Kotova T, Smirnova E, Borshchevskiy V, Cherezov V, Mishin A. Structural diversity of leukotriene G-protein coupled receptors. The Journal of Biological Chemistry. 105247. PMID 37703990 DOI: 10.1016/j.jbc.2023.105247  0.367
2023 Shiriaeva A, Martynowycz MW, Nicolas WJ, Cherezov V, Gonen T. MicroED structure of the human vasopressin 1B receptor. Biorxiv : the Preprint Server For Biology. PMID 37461729 DOI: 10.1101/2023.07.05.547888  0.426
2023 Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, Gerasimov A, Luginina A, Coucke Q, Bogorodskiy A, Gordeliy V, Wanninger S, Barth A, Mishin A, Hofkens J, ... Cherezov V, et al. Sub-millisecond conformational dynamics of the A adenosine receptor revealed by single-molecule FRET. Communications Biology. 6: 362. PMID 37012383 DOI: 10.1038/s42003-023-04727-z  0.308
2023 Barends TRM, Stauch B, Cherezov V, Schlichting I. Serial femtosecond crystallography. Nature Reviews. Methods Primers. 2. PMID 36643971 DOI: 10.1038/s43586-022-00141-7  0.322
2022 Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, ... ... Cherezov V, et al. GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A Adenosine Receptor. Journal of Medicinal Chemistry. PMID 35977382 DOI: 10.1021/acs.jmedchem.2c00462  0.355
2022 Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, ... ... Cherezov V, et al. Structural basis for receptor selectivity and inverse agonism in S1P receptors. Nature Communications. 13: 4736. PMID 35961984 DOI: 10.1038/s41467-022-32447-1  0.366
2022 Bolteau R, Duroux R, Laversin A, Vreulz B, Shiriaeva A, Stauch B, Han GW, Cherezov V, Renault N, Barczyk A, Ravez S, Coevoet M, Melnyk P, Liberelle M, Yous S. High ligand efficiency quinazoline compounds as novel A adenosine receptor antagonists. European Journal of Medicinal Chemistry. 241: 114620. PMID 35933788 DOI: 10.1016/j.ejmech.2022.114620  0.305
2022 Kovalev K, Astashkin R, Gordeliy V, Cherezov V. Crystallization of Microbial Rhodopsins. Methods in Molecular Biology (Clifton, N.J.). 2501: 125-146. PMID 35857226 DOI: 10.1007/978-1-0716-2329-9_6  0.367
2021 Martynowycz MW, Shiriaeva A, Ge X, Hattne J, Nannenga BL, Cherezov V, Gonen T. MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34462357 DOI: 10.1073/pnas.2106041118  0.497
2021 Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C. Molecular basis for lipid recognition by the prostaglandin D receptor CRTH2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34341104 DOI: 10.1073/pnas.2102813118  0.339
2021 Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971. PMID 34016973 DOI: 10.1038/s41467-021-23149-1  0.383
2021 Lemel L, Nieścierowicz K, García-Fernández MD, Darré L, Durroux T, Busnelli M, Pezet M, Rebeille F, Jouhet J, Mouillac B, Domene C, Chini B, Cherezov V, Moreau CJ. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. Journal of Lipid Research. 100059. PMID 33647276 DOI: 10.1016/j.jlr.2021.100059  0.324
2021 Marin E, Vakhrameev D, Gusach A, Luginina A, Kovalev K, Liu W, Weierstall U, Park J, Nam KH, Yunje C, Mishin A, Cherezov V, Borshchevskiy V. Abstract P-4: Robust Method for Background Subtraction in Serial X-ray Diffraction Data International Journal of Biomedicine. 11: S12-S12. DOI: 10.21103/ijbm.11.suppl_1.p4  0.396
2020 Sadybekov AA, Brouillette RL, Marin E, Sadybekov AV, Luginina A, Gusach A, Mishin A, Besserer-Offroy É, Longpré JM, Borshchevskiy V, Cherezov V, Sarret P, Katritch V. Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules. 10. PMID 33287369 DOI: 10.3390/biom10121634  0.371
2020 Lee MY, Geiger J, Ishchenko A, Han GW, Barty A, White TA, Gati C, Batyuk A, Hunter MS, Aquila A, Boutet S, Weierstall U, Cherezov V, Liu W. Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase. Iucrj. 7: 976-984. PMID 33209312 DOI: 10.1107/S2052252520012701  0.79
2020 Marin E, Luginina A, Gusach A, Kovalev K, Bukhdruker S, Khorn P, Polovinkin V, Lyapina E, Rogachev A, Gordeliy V, Mishin A, Cherezov V, Borshchevskiy V. Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs. Scientific Data. 7: 388. PMID 33184270 DOI: 10.1038/s41597-020-00729-2  0.413
2020 Shaye H, Ishchenko A, Lam JH, Han GW, Xue L, Rondard P, Pin JP, Katritch V, Gati C, Cherezov V. Structural basis of the activation of a metabotropic GABA receptor. Nature. PMID 32555460 DOI: 10.1038/S41586-020-2408-4  0.378
2020 Gusach A, Maslov I, Luginina A, Borshchevskiy V, Mishin A, Cherezov V. Beyond structure: emerging approaches to study GPCR dynamics. Current Opinion in Structural Biology. 63: 18-25. PMID 32305785 DOI: 10.1016/J.Sbi.2020.03.004  0.458
2020 Kuklin A, Zabelskii D, Gordeliy I, Teixeira J, Brûlet A, Chupin V, Cherezov V, Gordeliy V. On the Origin of the Anomalous Behavior of Lipid Membrane Properties in the Vicinity of the Chain-Melting Phase Transition. Scientific Reports. 10: 5749. PMID 32238845 DOI: 10.1038/S41598-020-62577-9  0.328
2020 Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, ... ... Cherezov V, et al. XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure (London, England : 1993). PMID 32142641 DOI: 10.1016/J.Str.2020.02.005  0.347
2020 Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang XP, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, et al. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature. PMID 32040955 DOI: 10.1038/s41586-020-2027-0  0.302
2019 Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, ... ... Cherezov V, et al. Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nature Communications. 10: 5573. PMID 31811124 DOI: 10.1038/s41467-019-13348-2  0.406
2019 Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, et al. Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists. Science Advances. 5: eaax9115. PMID 31807708 DOI: 10.1126/Sciadv.Aax9115  0.429
2019 Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, ... ... Cherezov V, et al. Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj. 6: 1106-1119. PMID 31709066 DOI: 10.1107/s2052252519013137  0.553
2019 Stauch B, Johansson LC, Cherezov V. Structural Insights into Melatonin Receptors. The Febs Journal. PMID 31693784 DOI: 10.1111/Febs.15128  0.493
2019 Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, ... ... Cherezov V, et al. Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Science Advances. 5: eaax2518. PMID 31633023 DOI: 10.1126/Sciadv.Aax2518  0.443
2019 Zhang Q, Cherezov V. Chemical tools for membrane protein structural biology. Current Opinion in Structural Biology. PMID 31285102 DOI: 10.1016/J.Sbi.2019.06.002  0.423
2019 Mishin A, Gusach A, Luginina A, Marin E, Borshchevskiy V, Cherezov V. An outlook on using serial femtosecond crystallography in drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 31184514 DOI: 10.1080/17460441.2019.1626822  0.373
2019 Martin-Garcia JM, Zhu L, Mendez D, Lee MY, Chun E, Li C, Hu H, Subramanian G, Kissick D, Ogata C, Henning R, Ishchenko A, Dobson Z, Zhang S, Weierstall U, ... ... Cherezov V, et al. High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. Iucrj. 6: 412-425. PMID 31098022 DOI: 10.2210/Pdb6Mh8/Pdb  0.743
2019 Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Cherezov V, et al. Publisher Correction: Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31048811 DOI: 10.1038/S41586-019-1209-0  0.332
2019 Gutierrez MG, Deyell J, White KL, Dalle Ore LC, Cherezov V, Stevens RC, Malmstadt N. The lipid phase preference of the adenosine A receptor depends on its ligand binding state. Chemical Communications (Cambridge, England). PMID 31038495 DOI: 10.1039/C8Cc10130B  0.389
2019 Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Cherezov V, et al. Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31019306 DOI: 10.1038/S41586-019-1141-3  0.443
2019 Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, ... ... Cherezov V, et al. XFEL structures of the human MT melatonin receptor reveal the basis of subtype selectivity. Nature. PMID 31019305 DOI: 10.1038/s41586-019-1144-0  0.479
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Cherezov V, et al. Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30573766 DOI: 10.1038/S41589-018-0214-1  0.323
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Cherezov V, et al. Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30510194 DOI: 10.1038/S41589-018-0160-Y  0.461
2018 Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu ZJ, Katritch V. Computational design of thermostabilizing point mutations for G protein-coupled receptors. Elife. 7. PMID 29927385 DOI: 10.7554/Elife.34729  0.388
2018 Ishchenko A, Gati C, Cherezov V. Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM. Current Opinion in Structural Biology. 51: 44-52. PMID 29554543 DOI: 10.1016/J.Sbi.2018.03.009  0.507
2018 Stauch B, Cherezov V. Serial Femtosecond Crystallography of G Protein-Coupled Receptors. Annual Review of Biophysics. PMID 29543504 DOI: 10.1146/Annurev-Biophys-070317-033239  0.527
2018 Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, ... ... Cherezov V, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011  0.765
2018 Broecker J, Morizumi T, Ou WL, Klingel V, Kuo A, Kissick DJ, Ishchenko A, Lee MY, Xu S, Makarov O, Cherezov V, Ogata CM, Ernst OP. High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nature Protocols. 13: 260-292. PMID 29300389 DOI: 10.1038/Nprot.2017.135  0.764
2018 Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu Z, Katritch V. Author response: Computational design of thermostabilizing point mutations for G protein-coupled receptors Elife. DOI: 10.7554/Elife.34729.019  0.325
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Cherezov V, et al. Crystal structure of EP3 receptor bound to misoprostol-FA Nature Chemical Biology. DOI: 10.2210/Pdb6M9T/Pdb  0.496
2017 Ishchenko A, Peng L, Zinovev E, Vlasov A, Lee SC, Kuklin A, Mishin A, Borshchevskiy V, Zhang Q, Cherezov V. Chemically Stable Lipids for Membrane Protein Crystallization. Crystal Growth & Design. 17: 3502-3511. PMID 29290736 DOI: 10.1021/Acs.Cgd.7B00458  0.427
2017 Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, ... ... Cherezov V, et al. Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. Iucrj. 4: 439-454. PMID 28875031 DOI: 10.1107/S205225251700570X  0.482
2017 Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, ... ... Cherezov V, et al. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell. 170: 457-469.e13. PMID 28753425 DOI: 10.1016/J.Cell.2017.07.002  0.418
2017 Johansson LC, Stauch B, Ishchenko A, Cherezov V. A Bright Future for Serial Femtosecond Crystallography with XFELs. Trends in Biochemical Sciences. PMID 28733116 DOI: 10.1016/J.Tibs.2017.06.007  0.441
2017 Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716900 DOI: 10.1073/Pnas.1700891114  0.44
2017 Padayatti PS, Leung JH, Mahinthichaichan P, Tajkhorshid E, Ishchenko A, Cherezov V, Soltis SM, Jackson JB, Stout CD, Gennis RB, Zhang Q. Critical Role of Water Molecules in Proton Translocation by the Membrane-Bound Transhydrogenase. Structure (London, England : 1993). PMID 28648609 DOI: 10.1016/J.Str.2017.05.022  0.328
2017 Zheng Y, Han GW, Abagyan R, Wu B, Stevens RC, Cherezov V, Kufareva I, Handel TM. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity. 46: 1005-1017.e5. PMID 28636951 DOI: 10.1016/J.Immuni.2017.05.002  0.331
2017 Ishchenko A, Abola EE, Cherezov V. Crystallization of Membrane Proteins: An Overview. Methods in Molecular Biology (Clifton, N.J.). 1607: 117-141. PMID 28573571 DOI: 10.1007/978-1-4939-7000-1_5  0.436
2017 Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, ... ... Cherezov V, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/Nature22363  0.448
2017 Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, ... ... Cherezov V, et al. Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nature Communications. 8: 15383. PMID 28513578 DOI: 10.1038/Ncomms15383  0.457
2017 Melnikov I, Polovinkin V, Kovalev K, Gushchin I, Shevtsov M, Shevchenko V, Mishin A, Alekseev A, Rodriguez-Valera F, Borshchevskiy V, Cherezov V, Leonard GA, Gordeliy V, Popov A. Fast iodide-SAD phasing for high-throughput membrane protein structure determination. Science Advances. 3: e1602952. PMID 28508075 DOI: 10.1126/Sciadv.1602952  0.501
2017 Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, ... ... Cherezov V, et al. Structural basis for selectivity and diversity in angiotensin II receptors. Nature. PMID 28379944 DOI: 10.1038/Nature22035  0.466
2016 Zheng Y, Qin L, Zacarías NV, de Vries H, Han GW, Gustavsson M, Dabros M, Zhao C, Cherney RJ, Carter P, Stamos D, Abagyan R, Cherezov V, Stevens RC, IJzerman AP, et al. Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature. PMID 27926736 DOI: 10.1038/Nature20605  0.448
2016 Ishchenko A, Cherezov V, Liu W. Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography. Journal of Visualized Experiments : Jove. PMID 27683972 DOI: 10.1016/J.Bpj.2015.11.383  0.523
2016 Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, ... ... Cherezov V, et al. Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Science Advances. 2: e1600292. PMID 27679816 DOI: 10.1126/Sciadv.1600292  0.787
2016 Zhu L, Weierstall U, Cherezov V, Liu W. Serial Femtosecond Crystallography of Membrane Proteins. Advances in Experimental Medicine and Biology. 922: 151-60. PMID 27553241 DOI: 10.1007/978-3-319-35072-1_11  0.499
2016 White TA, Barty A, Liu W, Ishchenko A, Zhang H, Gati C, Zatsepin NA, Basu S, Oberthür D, Metz M, Beyerlein KR, Yoon CH, Yefanov OM, James D, Wang D, ... ... Cherezov V, et al. Serial femtosecond crystallography datasets from G protein-coupled receptors. Scientific Data. 3: 160057. PMID 27479354 DOI: 10.1038/Sdata.2016.57  0.453
2016 Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, ... ... Cherezov V, et al. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific Data. 3: 160021. PMID 27070998 DOI: 10.1038/Sdata.2016.21  0.529
2016 Melnikov I, Polovinkin V, Kovalev K, Shevchenko V, Shevtsov M, Borshchevskiy V, Cherezov V, Leonard G, Gordeliy V, Popov A. Fast iodide-SAD phasing for membrane protein structure determination Acta Crystallographica Section A. 72. DOI: 10.1107/S2053273316097011  0.394
2016 Lee M, Patel N, Katritch V, Stevens RC, Cherezov V. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations Biophysical Journal. 110: 38a-39a. DOI: 10.1016/J.Bpj.2015.11.275  0.774
2015 Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu H, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang M, Boutet S, Coe J, Spence JC, Weierstall U, ... ... Cherezov V, et al. Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Structural Dynamics (Melville, N.Y.). 2: 041720. PMID 26798819 DOI: 10.1063/1.4929410  0.367
2015 Li D, Stansfeld PJ, Sansom MS, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, ... ... Cherezov V, et al. Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications. 6: 10140. PMID 26673816 DOI: 10.1038/Ncomms10140  0.371
2015 Heifetz A, Chudyk E, Gleave L, Aldeghi M, Cherezov V, Fedorov DG, Biggin PC, Bodkin M. The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions. Journal of Chemical Information and Modeling. PMID 26642258 DOI: 10.1021/Acs.Jcim.5B00644  0.41
2015 Miller RL, Thompson AA, Trapella C, Guerrini R, Malfacini D, Patel N, Han GW, Cherezov V, Caló G, Katritch V, Stevens RC. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure (London, England : 1993). PMID 26526853 DOI: 10.1016/J.Str.2015.07.024  0.465
2015 Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. The Journal of Biological Chemistry. PMID 26420482 DOI: 10.1074/Jbc.M115.689000  0.402
2015 Fromme R, Ishchenko A, Metz M, Chowdhury SR, Basu S, Boutet S, Fromme P, White TA, Barty A, Spence JC, Weierstall U, Liu W, Cherezov V. Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. Iucrj. 2: 545-51. PMID 26306196 DOI: 10.1107/S2052252515013160  0.484
2015 Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, ... ... Cherezov V, et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. PMID 26200343 DOI: 10.1038/Nature14656  0.494
2015 Conrad CE, Basu S, James D, Wang D, Schaffer A, Roy-Chowdhury S, Zatsepin NA, Aquila A, Coe J, Gati C, Hunter MS, Koglin JE, Kupitz C, Nelson G, Subramanian G, ... ... Cherezov V, et al. A novel inert crystal delivery medium for serial femtosecond crystallography. Iucrj. 2: 421-30. PMID 26177184 DOI: 10.1107/S2052252515009811  0.481
2015 Fenalti G, Abola EE, Wang C, Wu B, Cherezov V. Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP): A Precrystallization Assay for Membrane Proteins. Methods in Enzymology. 557: 417-37. PMID 25950976 DOI: 10.1016/Bs.Mie.2014.12.008  0.5
2015 Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, ... ... Cherezov V, et al. Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell. 161: 833-44. PMID 25913193 DOI: 10.1016/J.Cell.2015.04.011  0.43
2015 Nogly P, James D, Wang D, White TA, Zatsepin N, Shilova A, Nelson G, Liu H, Johansson L, Heymann M, Jaeger K, Metz M, Wickstrand C, Wu W, Båth P, ... ... Cherezov V, et al. Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. Iucrj. 2: 168-76. PMID 25866654 DOI: 10.1107/S2052252514026487  0.492
2015 Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, et al. Two disparate ligand-binding sites in the human P2Y1 receptor. Nature. 520: 317-21. PMID 25822790 DOI: 10.1038/Nature14287  0.468
2015 Heifetz A, Schertler GF, Seifert R, Tate CG, Sexton PM, Gurevich VV, Fourmy D, Cherezov V, Marshall FH, Storer RI, Moraes I, Tikhonova IG, Tautermann CS, Hunt P, Ceska T, et al. GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn-Schmiedeberg's Archives of Pharmacology. 388: 883-903. PMID 25772061 DOI: 10.1007/S00210-015-1111-8  0.415
2015 Fenalti G, Zatsepin NA, Betti C, Giguere P, Han GW, Ishchenko A, Liu W, Guillemyn K, Zhang H, James D, Wang D, Weierstall U, Spence JC, Boutet S, Messerschmidt M, ... ... Cherezov V, et al. Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nature Structural & Molecular Biology. 22: 265-8. PMID 25686086 DOI: 10.1038/Nsmb.2965  0.356
2015 Qin L, Kufareva I, Holden LG, Wang C, Zheng Y, Zhao C, Fenalti G, Wu H, Han GW, Cherezov V, Abagyan R, Stevens RC, Handel TM. Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science (New York, N.Y.). 347: 1117-22. PMID 25612609 DOI: 10.1126/Science.1261064  0.511
2015 Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH, Mordalski S, Pin JP, Stevens RC, Vriend G, Gloriam DE. Generic GPCR residue numbers - aligning topology maps while minding the gaps. Trends in Pharmacological Sciences. 36: 22-31. PMID 25541108 DOI: 10.1016/J.Tips.2014.11.001  0.402
2015 Bogorodskiy A, Frolov F, Mishin A, Round E, Polovinkin V, Cherezov V, Gordeliy VI, Büldt G, Gensch T, Borshchevskiy V. Nucleation and Growth of Membrane Protein Crystals In Meso—A Fluorescence Microscopy Study Crystal Growth & Design. 15: 5656-5660. DOI: 10.1021/Acs.Cgd.5B01061  0.405
2014 Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A. Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR. Biophysical Journal. 107: 2305-12. PMID 25418299 DOI: 10.1016/J.Bpj.2014.10.011  0.368
2014 Goren MA, Morizumi T, Menon I, Joseph JS, Dittman JS, Cherezov V, Stevens RC, Ernst OP, Menon AK. Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nature Communications. 5: 5115. PMID 25296113 DOI: 10.1038/Ncomms6115  0.432
2014 Liu W, Ishchenko A, Cherezov V. Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nature Protocols. 9: 2123-34. PMID 25122522 DOI: 10.1038/Nprot.2014.141  0.489
2014 Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nature Communications. 5: 4355. PMID 25008467 DOI: 10.1038/Ncomms5355  0.457
2014 Liu W, Wacker D, Wang C, Abola E, Cherezov V. Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130314. PMID 24914147 DOI: 10.1098/Rstb.2013.0314  0.546
2014 Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, et al. Agonist-bound structure of the human P2Y12 receptor. Nature. 509: 119-22. PMID 24784220 DOI: 10.1038/Nature13288  0.465
2014 Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC. Allosteric sodium in class A GPCR signaling. Trends in Biochemical Sciences. 39: 233-44. PMID 24767681 DOI: 10.1016/J.Tibs.2014.03.002  0.419
2014 Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, ... Cherezov V, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 509: 115-8. PMID 24670650 DOI: 10.1038/Nature13083  0.478
2014 Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC. Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science (New York, N.Y.). 344: 58-64. PMID 24603153 DOI: 10.1126/Science.1249489  0.417
2014 Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, ... ... Cherezov V, et al. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications. 5: 3309. PMID 24525480 DOI: 10.1038/Ncomms4309  0.5
2014 Fenalti G, Giguere PM, Katritch V, Huang XP, Thompson AA, Cherezov V, Roth BL, Stevens RC. Molecular control of δ-opioid receptor signalling. Nature. 506: 191-6. PMID 24413399 DOI: 10.1038/Nature12944  0.393
2014 Niescierowicz K, Caro L, Cherezov V, Vivaudou M, Moreau CJ. Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure (London, England : 1993). 22: 149-55. PMID 24268646 DOI: 10.1016/J.Str.2013.10.002  0.448
2014 Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A. Cholesterol-Gpcr (B2AR) Interaction in Lipidic Cubic Phase: Insight from 13C NMR Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3952  0.392
2013 Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, ... ... Cherezov V, et al. Serial femtosecond crystallography of G protein-coupled receptors. Science (New York, N.Y.). 342: 1521-4. PMID 24357322 DOI: 10.1126/Science.1244142  0.542
2013 Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. Structure (London, England : 1993). 21: 2175-85. PMID 24210756 DOI: 10.1016/J.Str.2013.09.020  0.378
2013 Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, Ma L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (New York, N.Y.). 341: 1387-90. PMID 24030490 DOI: 10.1126/Science.1241475  0.398
2013 Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Molecular Pharmacology. 84: 794-807. PMID 24021214 DOI: 10.1124/Mol.113.088054  0.419
2013 Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, et al. Structure of the human glucagon class B G-protein-coupled receptor. Nature. 499: 444-9. PMID 23863937 DOI: 10.1038/Nature12393  0.448
2013 Madden JT, Toth SJ, Dettmar CM, Newman JA, Oglesbee RA, Hedderich HG, Everly RM, Becker M, Ronau JA, Buchanan SK, Cherezov V, Morrow ME, Xu S, Ferguson D, Makarov O, et al. Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. Journal of Synchrotron Radiation. 20: 531-40. PMID 23765294 DOI: 10.1107/S0909049513007942  0.406
2013 Gater DL, Réat V, Czaplicki G, Saurel O, Milon A, Jolibois F, Cherezov V. Hydrogen bonding of cholesterol in the lipidic cubic phase Langmuir. 29: 8031-8038. PMID 23763339 DOI: 10.1021/La401351W  0.329
2013 Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC. Structure of the human smoothened receptor bound to an antitumour agent. Nature. 497: 338-43. PMID 23636324 DOI: 10.1038/Nature12167  0.459
2013 Kissick DJ, Dettmar CM, Becker M, Mulichak AM, Cherezov V, Ginell SL, Battaile KP, Keefe LJ, Fischetti RF, Simpson GJ. Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallographica. Section D, Biological Crystallography. 69: 843-51. PMID 23633594 DOI: 10.1107/S0907444913002746  0.446
2013 Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.). 340: 615-9. PMID 23519215 DOI: 10.1126/Science.1232808  0.439
2013 Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, ... ... Cherezov V, et al. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). 340: 610-4. PMID 23519210 DOI: 10.1126/Science.1232807  0.43
2013 Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K. The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Nature Reviews. Drug Discovery. 12: 25-34. PMID 23237917 DOI: 10.1038/Nrd3859  0.472
2013 Katritch V, Cherezov V, Stevens RC. Structure-function of the G protein-coupled receptor superfamily. Annual Review of Pharmacology and Toxicology. 53: 531-56. PMID 23140243 DOI: 10.1146/Annurev-Pharmtox-032112-135923  0.5
2013 Weierstall U, James D, Wang D, Spence JCH, Doak RB, Fromme P, Caffrey M, Cherezov V. Serial femtosecond crystallography of membrane proteins with a lipidic cubic phase injector Acta Crystallographica Section a Foundations of Crystallography. 69: s140-s141. DOI: 10.1107/S0108767313098814  0.366
2013 Niescierowicz KM, Caro L, Cherezov V, Vivaudou M, Moreau C. Functional Assessment of Crystallization-Optimized G Protein-Coupled Receptors using Ion Channel-Coupled Receptors Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.171  0.435
2012 Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M. Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. The Journal of Biological Chemistry. 287: 43063-70. PMID 23095758 DOI: 10.1074/jbc.M112.415091  0.323
2012 Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. Structural basis for allosteric regulation of GPCRs by sodium ions. Science (New York, N.Y.). 337: 232-6. PMID 22798613 DOI: 10.1126/Science.1219218  0.459
2012 Chun E, Thompson AA, Liu W, Roth CB, Griffith MT, Katritch V, Kunken J, Xu F, Cherezov V, Hanson MA, Stevens RC. Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (London, England : 1993). 20: 967-76. PMID 22681902 DOI: 10.1016/J.Str.2012.04.010  0.481
2012 Thompson AA, Liu W, Chun E, Katritch V, Wu H, Vardy E, Huang XP, Trapella C, Guerrini R, Calo G, Roth BL, Cherezov V, Stevens RC. Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature. 485: 395-9. PMID 22596163 DOI: 10.1038/Nature11085  0.442
2012 Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, et al. Structure of the human κ-opioid receptor in complex with JDTic. Nature. 485: 327-32. PMID 22437504 DOI: 10.1038/Nature10939  0.466
2012 Katritch V, Cherezov V, Stevens RC. Diversity and modularity of G protein-coupled receptor structures. Trends in Pharmacological Sciences. 33: 17-27. PMID 22032986 DOI: 10.1016/J.Tips.2011.09.003  0.526
2012 Fromme P, Chapman H, Kupitz C, Hunter MS, Kirian RA, Barty A, White TA, Aquilla A, Stellato F, Beyerlein K, DePonte DP, Frank M, Schlichting I, Shoeman R, Lomb L, ... ... Cherezov V, et al. Femtosecond nanocrystallography of membrane proteins opens a new era for structural biology Acta Crystallographica Section a Foundations of Crystallography. 68: s28-s28. DOI: 10.1107/S0108767312099461  0.395
2012 Weyand S, Shimamura T, Shiroshi M, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. The structure of the human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 68: s29-s29. DOI: 10.1107/S0108767312099448  0.381
2012 Gater D, Saurel O, Liu W, Cherezov V, Milon A. The Monoolein-Cholesterol Cubic Phase: Characterization by NMR Spectroscopy Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2129  0.514
2012 Joseph JS, Abola EE, Cherezov V. Structural Insights into Cholesterol Interactions with G-Protein-Coupled Receptors Cholesterol Regulation of Ion Channels and Receptors. 231-253. DOI: 10.1002/9781118342312.ch11  0.308
2011 Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, Cherezov V, Stevens RC. GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods (San Diego, Calif.). 55: 310-7. PMID 22041719 DOI: 10.1016/J.Ymeth.2011.10.011  0.474
2011 Joseph JS, Liu W, Kunken J, Weiss TM, Tsuruta H, Cherezov V. Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods (San Diego, Calif.). 55: 342-9. PMID 21903166 DOI: 10.1016/J.Ymeth.2011.08.013  0.453
2011 Tiefenbrunn T, Liu W, Chen Y, Katritch V, Stout CD, Fee JA, Cherezov V. High resolution structure of the ba3 cytochrome c oxidase from thermus thermophilus in a lipidic environment Plos One. 6. PMID 21814577 DOI: 10.1371/Journal.Pone.0022348  0.4
2011 Cherezov V. Lipidic cubic phase technologies for membrane protein structural studies. Current Opinion in Structural Biology. 21: 559-66. PMID 21775127 DOI: 10.1016/J.Sbi.2011.06.007  0.499
2011 Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor complex with doxepin. Nature. 475: 65-70. PMID 21697825 DOI: 10.1038/Nature10236  0.377
2011 Xu F, Liu W, Hanson MA, Stevens RC, Cherezov V. Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal Growth & Design. 11: 1193-1201. PMID 21660116 DOI: 10.1021/Cg101385E  0.493
2011 Liu W, Cherezov V. Crystallization of membrane proteins in lipidic mesophases. Journal of Visualized Experiments : Jove. PMID 21490572 DOI: 10.3791/2501  0.481
2011 Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Structure of an agonist-bound human A2A adenosine receptor. Science (New York, N.Y.). 332: 322-7. PMID 21393508 DOI: 10.1126/Science.1202793  0.44
2011 Iwata S, Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC. Molecular basis of antihistamine specificity against human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 67: C17-C17. DOI: 10.1107/S0108767311099648  0.331
2011 Cherezov V, Wu B, Chien E, Liu W, Xu F, Stevens RC. Structural biology of G protein-coupled receptors Acta Crystallographica Section a Foundations of Crystallography. 67: C132-C132. DOI: 10.1107/S0108767311096760  0.428
2011 Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor with doxepin Acta Crystallographica Section a Foundations of Crystallography. 67: C185-C186. DOI: 10.1107/S0108767311095377  0.381
2010 Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/Science.1197410  0.409
2010 Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (New York, N.Y.). 330: 1066-71. PMID 20929726 DOI: 10.1126/Science.1194396  0.455
2010 Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC. Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. Journal of the American Chemical Society. 132: 11443-5. PMID 20669948 DOI: 10.1021/Ja105108Q  0.447
2010 Cherezov V, Abola E, Stevens RC. Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets. Methods in Molecular Biology (Clifton, N.J.). 654: 141-68. PMID 20665265 DOI: 10.1007/978-1-60761-762-4_8  0.505
2010 Liu W, Hanson MA, Stevens RC, Cherezov V. LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophysical Journal. 98: 1539-48. PMID 20409473 DOI: 10.1016/J.Bpj.2009.12.4296  0.43
2010 Kissick DJ, Gualtieri EJ, Simpson GJ, Cherezov V. Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases. Analytical Chemistry. 82: 491-7. PMID 20025250 DOI: 10.1021/Ac902139W  0.402
2009 Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC. Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. Journal of the Royal Society, Interface / the Royal Society. 6: S587-97. PMID 19535414 DOI: 10.1098/Rsif.2009.0142.Focus  0.5
2009 Caffrey M, Cherezov V. Crystallizing membrane proteins using lipidic mesophases. Nature Protocols. 4: 706-31. PMID 19390528 DOI: 10.1038/Nprot.2009.31  0.474
2009 Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of Molecular Recognition : Jmr. 22: 307-18. PMID 19353579 DOI: 10.1002/Jmr.949  0.44
2009 Weis WI, Rosenbaum DM, Rasmussen SGF, Choi HJ, Thian FS, Kobilka TS, Yao XJ, Day PW, Parnot C, Fung JJ, Ratnala VRP, Kobilka BK, Cherezov V, Hanson MA, Kuhn P, et al. Crystal structures of the β2-adrenergic receptor Nato Science For Peace and Security Series a: Chemistry and Biology. 217-230.  0.334
2008 Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC. LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Crystal Growth & Design. 8: 4307-4315. PMID 19234616 DOI: 10.1021/Cg800778J  0.44
2008 Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science (New York, N.Y.). 322: 1211-7. PMID 18832607 DOI: 10.1126/Science.1164772  0.518
2008 Cherezov V, Höfer N, Szebenyi DM, Kolaj O, Wall JG, Gillilan R, Srinivasan V, Jaroniec CP, Caffrey M. Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus. Structure (London, England : 1993). 16: 1378-88. PMID 18786400 DOI: 10.1016/J.Str.2008.05.014  0.347
2008 Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure (London, England : 1993). 16: 897-905. PMID 18547522 DOI: 10.1016/J.Str.2008.05.001  0.466
2008 Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M. In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins. 71: 24-34. PMID 18076035 DOI: 10.1002/Prot.21841  0.483
2007 Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (New York, N.Y.). 318: 1258-65. PMID 17962520 DOI: 10.1126/Science.1150577  0.519
2007 Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science (New York, N.Y.). 318: 1266-73. PMID 17962519 DOI: 10.1126/Science.1150609  0.484
2007 Cherezov V, Caffrey M. Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction. Faraday Discussions. 136: 195-212; discussion . PMID 17955811 DOI: 10.1039/B618173B  0.497
2007 Höfer N, Kolaj O, Li H, Cherezov V, Gillilan R, Wall JG, Caffrey M. Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 673-7. PMID 17671365 DOI: 10.1107/S1744309107032277  0.408
2007 Peddi A, Muthusubramaniam L, Zheng YF, Cherezov V, Misquitta Y, Caffrey M. High-throughput automated system for crystallizing membrane proteins in lipidic mesophases Ieee Transactions On Automation Science and Engineering. 4: 129-139. DOI: 10.1109/Tase.2006.880541  0.412
2006 Cherezov V, Yamashita E, Liu W, Zhalnina M, Cramer WA, Caffrey M. In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. Journal of Molecular Biology. 364: 716-34. PMID 17028020 DOI: 10.1016/J.Jmb.2006.09.022  0.445
2006 Shaikh SR, Cherezov V, Caffrey M, Soni SP, LoCascio D, Stillwell W, Wassall SR. Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. Journal of the American Chemical Society. 128: 5375-83. PMID 16620109 DOI: 10.1021/Ja057949B  0.306
2006 Cherezov V, Clogston J, Papiz MZ, Caffrey M. Room to move: crystallizing membrane proteins in swollen lipidic mesophases. Journal of Molecular Biology. 357: 1605-18. PMID 16490208 DOI: 10.1016/J.Jmb.2006.01.049  0.481
2006 Raman P, Cherezov V, Caffrey M. The Membrane Protein Data Bank Cellular and Molecular Life Sciences. 63: 36-51. PMID 16314922 DOI: 10.1007/S00018-005-5350-6  0.452
2006 Siegel DP, Cherezov V, Greathouse DV, Koeppe RE, Killian JA, Caffrey M. Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion. Biophysical Journal. 90: 200-11. PMID 16214859 DOI: 10.1529/Biophysj.105.070466  0.326
2006 Cherezov V, Caffrey M. Picolitre-scale crystallization of membrane proteins Journal of Applied Crystallography. 39: 604-606. DOI: 10.1107/S0021889806022953  0.451
2005 Cherezov V, Caffrey M. A simple and inexpensive nanoliter-volume dispenser for highly viscous materials used in membrane protein crystallization Journal of Applied Crystallography. 38: 398-400. DOI: 10.1107/S0021889805001640  0.402
2004 Misquitta LV, Misquitta Y, Cherezov V, Slattery O, Mohan JM, Hart D, Zhalnina M, Cramer WA, Caffrey M. Membrane protein crystallization in lipidic mesophases with tailored bilayers Structure. 12: 2113-2124. PMID 15576026 DOI: 10.1016/J.Str.2004.09.020  0.412
2004 Wassall SR, Brzustowicz MR, Shaikh SR, Cherezov V, Caffrey M, Stillwell W. Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chemistry and Physics of Lipids. 132: 79-88. PMID 15530450 DOI: 10.1016/J.Chemphyslip.2004.09.007  0.324
2004 Misquitta Y, Cherezov V, Havas F, Patterson S, Mohan JM, Wells AJ, Hart DJ, Caffrey M. Rational design of lipid for membrane protein crystallization. Journal of Structural Biology. 148: 169-75. PMID 15477097 DOI: 10.1016/J.Jsb.2004.06.008  0.454
2004 Cherezov V, Peddi A, Muthusubramaniam L, Zheng YF, Caffrey M. A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases. Acta Crystallographica. Section D, Biological Crystallography. 60: 1795-807. PMID 15388926 DOI: 10.1107/S0907444904019109  0.364
2004 Wassall SR, Shaikh SR, Brzustowicz MR, Cherezov V, Siddigui RA, Caffrey M, Stillwell W. Interaction of polyunsaturated fatty acids with cholesterol: A role in lipid raft phase separation Macromolecular Symposia. 219: 73-83. DOI: 10.1002/Masy.200550108  0.323
2003 Cherezov V, Siegel DP, Shaw W, Burgess SW, Caffrey M. The kinetics of non-lamellar phase formation in DOPE-Me: relevance to biomembrane fusion. The Journal of Membrane Biology. 195: 165-182. PMID 14724762 DOI: 10.1007/S00232-003-0617-Z  0.308
2003 Shaikh SR, Cherezov V, Caffrey M, Stillwell W, Wassall SR. Interaction of cholesterol with a docosahexaenoic acid-containing phosphatidylethanolamine: trigger for microdomain/raft formation? Biochemistry. 42: 12028-37. PMID 14556634 DOI: 10.1021/Bi034931+  0.325
2003 Cherezov V, Caffrey M. Nano-volume plates with excellent optical properties for fast, inexpensive crystallization screening of membrane proteins Journal of Applied Crystallography. 36: 1372-1377. DOI: 10.1107/S002188980301906X  0.426
2002 Cherezov V, Clogston J, Misquitta Y, Abdel-Gawad W, Caffrey M. Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. Biophysical Journal. 83: 3393-407. PMID 12496106 DOI: 10.1016/S0006-3495(02)75339-3  0.421
2002 Cherezov V, Riedl KM, Caffrey M. Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases. Journal of Synchrotron Radiation. 9: 333-41. PMID 12409619 DOI: 10.1107/S0909049502014528  0.33
2002 Brzustowicz MR, Cherezov V, Zerouga M, Caffrey M, Stillwell W, Wassall SR. Controlling membrane cholesterol content. A role for polyunsaturated (docosahexaenoate) phospholipids. Biochemistry. 41: 12509-19. PMID 12369842 DOI: 10.1021/Bi0262808  0.332
2002 Brzustowicz MR, Cherezov V, Caffrey M, Stillwell W, Wassall SR. Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation. Biophysical Journal. 82: 285-98. PMID 11751316 DOI: 10.1016/S0006-3495(02)75394-0  0.328
2001 Cherezov V, Fersi H, Caffrey M. Crystallization screens: compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins. Biophysical Journal. 81: 225-42. PMID 11423409 DOI: 10.1016/S0006-3495(01)75694-9  0.363
1996 Klose G, Islamov A, König B, Cherezov V. Structure of Mixed Multilayers of Palmitoyloleoylphosphatidylcholine and Oligo(oxyethylene glycol) Monododecyl Ether Determined by X-ray and Neutron Diffraction Langmuir. 12: 409-415. DOI: 10.1021/La950383S  0.367
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