Year |
Citation |
Score |
2022 |
Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova EI, Berezhnov AV, De S, Peddie CJ, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick AI, Zanjani ZS, et al. Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity. Nature Neuroscience. PMID 36261654 DOI: 10.1038/s41593-022-01206-2 |
0.673 |
|
2022 |
Emin D, Zhang YP, Lobanova E, Miller A, Li X, Xia Z, Dakin H, Sideris DI, Lam JYL, Ranasinghe RT, Kouli A, Zhao Y, De S, Knowles TPJ, Vendruscolo M, et al. Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease. Nature Communications. 13: 5512. PMID 36127374 DOI: 10.1038/s41467-022-33252-6 |
0.518 |
|
2022 |
Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova EI, Berezhnov AV, De S, Peddie CJ, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick AI, Zanjani ZS, et al. Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity. Nature Neuroscience. PMID 36042314 DOI: 10.1038/s41593-022-01140-3 |
0.698 |
|
2022 |
Meng JX, Zhang Y, Saman D, Haider AM, De S, Sang JC, Brown K, Jiang K, Humphrey J, Julian L, Hidari E, Lee SF, Balmus G, Floto RA, Bryant CE, et al. Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses. Nature Communications. 13: 2692. PMID 35577786 DOI: 10.1038/s41467-022-30461-x |
0.62 |
|
2021 |
Jannasch A, Szilagyi SA, Burmeister M, Davis QT, Hermsdorf GL, De S, Schäffer E. Fast 3D imaging of giant unilamellar vesicles using reflected light-sheet microscopy with single molecule sensitivity. Journal of Microscopy. PMID 34786705 DOI: 10.1111/jmi.13070 |
0.607 |
|
2021 |
Sideris DI, Danial JSH, Emin D, Ruggeri FS, Xia Z, Zhang YP, Lobanova E, Dakin H, De S, Miller A, Sang JC, Knowles TPJ, Vendruscolo M, Fraser G, Crowther D, et al. Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer's disease. Brain Communications. 3: fcab147. PMID 34396107 DOI: 10.1093/braincomms/fcab147 |
0.471 |
|
2021 |
Vilalta A, Zhou Y, Sevalle J, Griffin JK, Satoh K, Allendorf DH, De S, Puigdellívol M, Bruzas A, Burguillos MA, Dodd RB, Chen F, Zhang Y, Flagmeier P, Needham LM, et al. Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation. The Journal of Biological Chemistry. 100631. PMID 33823153 DOI: 10.1016/j.jbc.2021.100631 |
0.61 |
|
2020 |
Whiten DR, Brownjohn PW, Moore S, De S, Strano A, Zuo Y, Haneklaus M, Klenerman D, Livesey FJ. Tumour necrosis factor induces increased production of extracellular amyloid-β- and α-synuclein-containing aggregates by human Alzheimer's disease neurons. Brain Communications. 2: fcaa146. PMID 33543132 DOI: 10.1093/braincomms/fcaa146 |
0.492 |
|
2020 |
Angelova PR, Choi ML, Berezhnov AV, Horrocks MH, Hughes CD, De S, Rodrigues M, Yapom R, Little D, Dolt KS, Kunath T, Devine MJ, Gissen P, Shchepinov MS, Sylantyev S, et al. Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation. Cell Death and Differentiation. PMID 33041329 DOI: 10.1038/s41418-020-00634-6 |
0.663 |
|
2020 |
Flagmeier P, De S, Michaels TCT, Yang X, Dear AJ, Emanuelsson C, Vendruscolo M, Linse S, Klenerman D, Knowles TPJ, Dobson CM. Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation. Nature Structural & Molecular Biology. PMID 32778821 DOI: 10.1038/S41594-020-0471-Z |
0.564 |
|
2020 |
Angelova PR, Choi ML, Berezhnov AV, Horrocks MH, Hughes CD, De S, Rodrigues M, Yapom R, Little D, Dolt KS, Kunath T, Devine MJ, Gissen P, Shchepinov MS, Sylantyev S, et al. Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation. Cell Death and Differentiation. PMID 32409771 DOI: 10.1038/S41418-020-0552-X |
0.682 |
|
2020 |
Angelova PR, Choi ML, Berezhnov AV, Horrocks MH, Hughes CD, De S, Rodrigues M, Yapom R, Little D, Dolt KS, Kunath T, Devine MJ, Gissen P, Shchepinov MS, Sylantyev S, et al. Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation. Cell Death and Differentiation. PMID 32341450 DOI: 10.1038/S41418-020-0542-Z |
0.71 |
|
2020 |
Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, et al. Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain Communications. 2: fcaa010. PMID 32280944 DOI: 10.1093/braincomms/fcaa010 |
0.476 |
|
2020 |
Choi ML, Horrocks MH, Rodrigues M, De S, Tosatto L, Zhang W, Virdi G, Klenerman D, Abramov AY, Gandhi S. Tracking Oligomerization of Alpha-Synuclein Demonstrates Pivotal Role of Mitochondria in Seeding Biophysical Journal. 118: 217a. DOI: 10.1016/J.Bpj.2019.11.1289 |
0.668 |
|
2019 |
De S, Whiten DR, Ruggeri FS, Hughes C, Rodrigues M, Sideris DI, Taylor CG, Aprile FA, Muyldermans S, Knowles TPJ, Vendruscolo M, Bryant C, Blennow K, Skoog I, Kern S, et al. Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression. Acta Neuropathologica Communications. 7: 120. PMID 31349874 DOI: 10.1186/S40478-019-0777-4 |
0.556 |
|
2019 |
Sang JC, Lee JE, Dear AJ, De S, Meisl G, Thackray AM, Bujdoso R, Knowles TPJ, Klenerman D. Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species. Chemical Science. 10: 4588-4597. PMID 31123569 DOI: 10.1039/C8Sc05627G |
0.57 |
|
2019 |
De S, Wirthensohn DC, Flagmeier P, Hughes C, Aprile FA, Ruggeri FS, Whiten DR, Emin D, Xia Z, Varela JA, Sormanni P, Kundel F, Knowles TPJ, Dobson CM, Bryant C, et al. Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms. Nature Communications. 10: 1541. PMID 30948723 DOI: 10.1038/S41467-019-09477-3 |
0.56 |
|
2019 |
Weiffert T, Meisl G, Flagmeier P, De S, Dunning CJR, Frohm B, Zetterberg H, Blennow K, Portelius E, Klenerman D, Dobson CM, Knowles TPJ, Linse S. Increased secondary nucleation underlies accelerated aggregation of the four-residue N-terminally truncated Aβ42 species Aβ5-42. Acs Chemical Neuroscience. PMID 30793584 DOI: 10.1021/Acschemneuro.8B00676 |
0.524 |
|
2019 |
De S, Klenerman D. Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease. Biochimica Et Biophysica Acta. Proteins and Proteomics. PMID 30611780 DOI: 10.1016/J.Bbapap.2018.12.010 |
0.568 |
|
2019 |
De S, Whiten DR, Hughes C, Klenerman D. O3-01-03: MECHANISM OF TOXICITY INDUCED BY AMYLOID-BETA AGGREGATES CHANGES DURING THE PROGRESSION OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P875-P876. DOI: 10.1016/J.Jalz.2019.06.4626 |
0.506 |
|
2018 |
Lee JE, Sang JC, Rodrigues M, Carr AR, Horrocks MH, De S, Bongiovanni MN, Flagmeier P, Dobson CM, Wales DJ, Lee SF, Klenerman D. Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale. Nano Letters. PMID 30380895 DOI: 10.1021/Acs.Nanolett.8B02916 |
0.771 |
|
2018 |
Iljina M, Dear AJ, Garcia GA, De S, Tosatto L, Flagmeier P, Whiten DR, Michaels TCT, Frenkel D, Dobson CM, Knowles TPJ, Klenerman D. Quantifying Co-Oligomer Formation by α-Synuclein. Acs Nano. PMID 30371053 DOI: 10.1021/Acsnano.8B03575 |
0.55 |
|
2018 |
Horrocks M, Whiten DR, Zuo Y, Calo L, Choi ML, De S, Flagmeier P, Wirthensohn DC, Kundel F, Lee SF, Dobson C, Gandhi S, Spillantini M, Klenerman D, Ranasinghe RT, et al. Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells. Chembiochem : a European Journal of Chemical Biology. PMID 30051958 DOI: 10.1002/Cbic.201800209 |
0.772 |
|
2018 |
Whiten DR, Cox D, Horrocks MH, Taylor CG, De S, Flagmeier P, Tosatto L, Kumita JR, Ecroyd H, Dobson CM, Klenerman D, Wilson MR. Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers. Cell Reports. 23: 3492-3500. PMID 29924993 DOI: 10.1016/J.Celrep.2018.05.074 |
0.712 |
|
2018 |
Varela JA, Rodrigues M, De S, Flagmeier P, Gandhi S, Dobson CM, Klenerman D, Lee S. Optical structural analysis of individual α-synuclein oligomers. Angewandte Chemie (International Ed. in English). PMID 29342318 DOI: 10.1002/Anie.201710779 |
0.671 |
|
2018 |
Kundel F, De S, Flagmeier P, Horrocks MH, Kjaergaard M, Shammas SL, Jackson SE, Dobson CM, Klenerman D. Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity. Acs Chemical Biology. PMID 29300447 DOI: 10.1021/Acschembio.7B01039 |
0.719 |
|
2018 |
Whiten DR, Zuo Y, Calo L, Choi M, De S, Flagmeier P, Wirthensohn DC, Kundel F, Ranasinghe RT, Sanchez SE, Athauda D, Lee SF, Dobson CM, Gandhi S, Spillantini M, et al. Cover Feature: Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells (ChemBioChem 19/2018) Chembiochem. 19: 2001-2001. DOI: 10.1002/Cbic.201800547 |
0.741 |
|
2017 |
Drews A, De S, Flagmeier P, Wirthensohn DC, Chen WH, Whiten DR, Rodrigues M, Vincke C, Muyldermans S, Paterson RW, Slattery CF, Fox NC, Schott JM, Zetterberg H, Dobson CM, et al. Inhibiting the Ca2+ Influx Induced by Human CSF. Cell Reports. 21: 3310-3316. PMID 29241555 DOI: 10.1016/J.Celrep.2017.11.057 |
0.517 |
|
2017 |
Schellhaus AK, Moreno-Andrés D, Chugh M, Yokoyama H, Moschopoulou A, De S, Bono F, Hipp K, Schäffer E, Antonin W. Developmentally Regulated GTP binding protein 1 (DRG1) controls microtubule dynamics. Scientific Reports. 7: 9996. PMID 28855639 DOI: 10.1038/S41598-017-10088-5 |
0.61 |
|
2017 |
Flagmeier P, De S, Wirthensohn DC, Lee SF, Vincke C, Muyldermans S, Knowles TPJ, Gandhi S, Dobson CM, Klenerman D. Ultrasensitive Measurement of Ca(2+) Influx into Lipid Vesicles Induced by Protein Aggregates. Angewandte Chemie (International Ed. in English). PMID 28474754 DOI: 10.1002/Anie.201700966 |
0.655 |
|
2017 |
Sharma DK, Irfanullah M, Basu SK, Madhu S, De S, Jadhav S, Ravikanth M, Chowdhury A. An approach to estimate spatial distribution of analyte within cells using spectrally-resolved fluorescence microscopy. Methods and Applications in Fluorescence. 5: 014003. PMID 28099171 DOI: 10.1088/2050-6120/5/1/014003 |
0.749 |
|
2017 |
Jannasch A, Abdosamadi MK, Ramaiya A, De S, Ferro V, Sonnberger A, Schäffer E. Custom-Made Microspheres for Optical Tweezers. Methods in Molecular Biology (Clifton, N.J.). 1486: 137-155. PMID 27844428 DOI: 10.1007/978-1-4939-6421-5_6 |
0.608 |
|
2017 |
Irfanullah M, Sharma DK, Chulliyil R, Layek A, De S, Chowdhury A. Heterogeneity in optical properties of near white-light emissive europium complex species revealed by spectroscopy of single nanoaggregates Chemical Physics Letters. 667: 247-253. DOI: 10.1016/J.Cplett.2016.10.065 |
0.688 |
|
2016 |
Bhattacharya S, Sharma DK, De S, Mahato J, Chowdhury A. Heterogeneity during Plasticization of Poly(vinylpyrrolidone): Insights from Reorientational Mobility of Single Fluorescent Probes. The Journal of Physical Chemistry. B. 120: 12404-12415. PMID 27934224 DOI: 10.1021/Acs.Jpcb.6B08584 |
0.729 |
|
2013 |
Hazarika A, Layek A, De S, Nag A, Debnath S, Mahadevan P, Chowdhury A, Sarma DD. Ultranarrow and widely tunable Mn2+-Induced photoluminescence from single Mn-doped nanocrystals of ZnS-CdS alloys. Physical Review Letters. 110: 267401. PMID 23848921 DOI: 10.1103/Physrevlett.110.267401 |
0.768 |
|
2013 |
Bhattacharya S, Sharma DK, Saurabh S, De S, Sain A, Nandi A, Chowdhury A. Plasticization of poly(vinylpyrrolidone) thin films under ambient humidity: insight from single-molecule tracer diffusion dynamics. The Journal of Physical Chemistry. B. 117: 7771-82. PMID 23777572 DOI: 10.1021/Jp401704E |
0.748 |
|
2012 |
De S, Layek A, Bhattacharya S, Kumar Das D, Kadir A, Bhattacharya A, Dhar S, Chowdhury A. Quantum-confined stark effect in localized luminescent centers within InGaN/GaN quantum-well based light emitting diodes Applied Physics Letters. 101. DOI: 10.1063/1.4754079 |
0.766 |
|
2011 |
Layek A, De S, Thorat R, Chowdhury A. Spectrally Resolved Photoluminescence Imaging of ZnO Nanocrystals at Single-Particle Levels. The Journal of Physical Chemistry Letters. 2: 1241-7. PMID 26295417 DOI: 10.1021/Jz200370S |
0.765 |
|
2011 |
De S, Kumar Das D, Layek A, Raja A, Kumar Singh M, Bhattacharya A, Dhar S, Chowdhury A. Optoelectronic behaviors and carrier dynamics of individual localized luminescent centers in InGaN quantum-well light emitting diodes Applied Physics Letters. 99. DOI: 10.1063/1.3671092 |
0.779 |
|
2011 |
Ghosh A, Bhasker HP, Mukherjee A, Kundu T, Singh BP, Dhar S, De S, Chowdhury A. Polarity selective etching: A self-assisted route for fabricating high density of c-axis oriented tapered GaN nanopillars Journal of Applied Physics. 110: 033528. DOI: 10.1063/1.3622142 |
0.419 |
|
2011 |
De S, Layek A, Raja A, Kadir A, Gokhale MR, Bhattacharya A, Dhar S, Chowdhury A. Light-Emitting Diodes: Two Distinct Origins of Highly Localized Luminescent Centers within InGaN/GaN Quantum-Well Light-Emitting Diodes (Adv. Funct. Mater. 20/2011) Advanced Functional Materials. 21: 3827-3827. DOI: 10.1002/Adfm.201190086 |
0.767 |
|
2011 |
De S, Layek A, Raja A, Kadir A, Gokhale MR, Bhattacharya A, Dhar S, Chowdhury A. Two distinct origins of highly localized luminescent centers within InGaN/GaN quantum-well light-emitting diodes Advanced Functional Materials. 21: 3828-3835. DOI: 10.1002/Adfm.201100894 |
0.777 |
|
2006 |
Whiten DR, Brownjohn PW, Moore S, De S, Zuo Y, Livesey R, Klenerman D. P2-176: PROTEIN AGGREGATION AND NEUROINFLAMMATION ARE INTERRELATED IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P736-P736. DOI: 10.1016/J.Jalz.2018.06.863 |
0.515 |
|
2006 |
De S, Klenerman D. O1-01-01: CHARACTERIZING PROTEIN AGGREGATES FROM THE HUMAN BRAIN Alzheimer's & Dementia. 14: P212-P212. DOI: 10.1016/J.Jalz.2018.06.2330 |
0.488 |
|
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