Scott Shaffer - Publications

Affiliations: 
1996-2001 University of Washington, Seattle, Seattle, WA 

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Canterbury JD, Merrihew GE, MacCoss MJ, Goodlett DR, Shaffer SA. Comparison of data acquisition strategies on quadrupole ion trap instrumentation for shotgun proteomics. Journal of the American Society For Mass Spectrometry. 25: 2048-59. PMID 25261218 DOI: 10.1007/S13361-014-0981-1  0.504
2014 Swiderski K, Shaffer SA, Gallis B, Odom GL, Arnett AL, Scott Edgar J, Baum DM, Chee A, Naim T, Gregorevic P, Murphy KT, Moody J, Goodlett DR, Lynch GS, Chamberlain JS. Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting. Human Molecular Genetics. 23: 6697-711. PMID 25082828 DOI: 10.1093/Hmg/Ddu388  0.43
2014 Canterbury JD, Merrihew GE, MacCoss MJ, Goodlett DR, Shaffer SA. Comparison of data acquisition strategies on quadrupole ion trap instrumentation for shotgun proteomics Journal of the American Society For Mass Spectrometry. 25: 2048-2059. DOI: 10.1007/s13361-014-0981-1  0.48
2012 Zhao C, Gao Q, Roberts AG, Shaffer SA, Doneanu CE, Xue S, Goodlett DR, Nelson SD, Atkins WM. Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5). Biochemistry. 51: 9488-500. PMID 23150942 DOI: 10.1021/Bi301069R  0.407
2012 Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nature Immunology. 13: 1010-9. PMID 22922362 DOI: 10.1038/Ni.2402  0.419
2012 Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 8716-21. PMID 22586119 DOI: 10.1073/Pnas.1202908109  0.428
2012 Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CRH, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria (Proceedings of the National Academy of Sciences United States of America (2012) 109, (8716-8721) DOI: 10.1073/pnas.1202908109)) Proceedings of the National Academy of Sciences of the United States of America. 109: 13877. DOI: 10.1073/Pnas.1212463109  0.376
2011 Foss EJ, Radulovic D, Shaffer SA, Goodlett DR, Kruglyak L, Bedalov A. Genetic variation shapes protein networks mainly through non-transcriptional mechanisms. Plos Biology. 9: e1001144. PMID 21909241 DOI: 10.1371/Journal.Pbio.1001144  0.426
2011 Thatcher JE, Buttrick B, Shaffer SA, Shimshoni JA, Goodlett DR, Nelson WL, Isoherranen N. Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase. Molecular Pharmacology. 80: 228-39. PMID 21521770 DOI: 10.1124/Mol.111.072413  0.398
2011 Ting YS, Shaffer SA, Jones JW, Ng WV, Ernst RK, Goodlett DR. Automated lipid A structure assignment from hierarchical tandem mass spectrometry data. Journal of the American Society For Mass Spectrometry. 22: 856-66. PMID 21472520 DOI: 10.1007/S13361-010-0055-Y  0.619
2011 Panchaud A, Jung S, Shaffer SA, Aitchison JD, Goodlett DR. Faster, quantitative, and accurate precursor acquisition independent from ion count. Analytical Chemistry. 83: 2250-7. PMID 21341720 DOI: 10.1021/Ac103079Q  0.506
2011 Chu LJ, Chen MC, Setter J, Tsai YS, Yang H, Fang X, Ting YS, Shaffer SA, Taylor GK, von Haller PD, Goodlett DR, Ng WV. New structural proteins of Halobacterium salinarum gas vesicle revealed by comparative proteomics analysis. Journal of Proteome Research. 10: 1170-8. PMID 21158390 DOI: 10.1021/Pr1009383  0.48
2010 Chakrabarti L, Zahra R, Jackson SM, Kazemi-Esfarjani P, Sopher BL, Mason AG, Toneff T, Ryu S, Shaffer S, Kansy JW, Eng J, Merrihew G, MacCoss MJ, Murphy A, Goodlett DR, et al. Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. Neuron. 66: 835-47. PMID 20620870 DOI: 10.1016/J.Neuron.2010.05.024  0.486
2010 Heron SR, Wilson R, Shaffer SA, Goodlett DR, Cooper JM. Surface acoustic wave nebulization of peptides as a microfluidic interface for mass spectrometry. Analytical Chemistry. 82: 3985-9. PMID 20364823 DOI: 10.1021/Ac100372C  0.505
2010 Panchaud A, Singh P, Shaffer SA, Goodlett DR. xComb: a cross-linked peptide database approach to protein-protein interaction analysis. Journal of Proteome Research. 9: 2508-15. PMID 20302351 DOI: 10.1021/Pr9011816  0.457
2010 Gharib SA, Nguyen E, Altemeier WA, Shaffer SA, Doneanu CE, Goodlett DR, Schnapp LM. Of mice and men: Comparative proteomics of bronchoalveolar fluid European Respiratory Journal. 35: 1388-1395. PMID 20032019 DOI: 10.1183/09031936.00089409  0.439
2010 Parra MC, Shaffer SA, Hajjar AM, Gallis BM, Hager A, Goodlett DR, Guina T, Miller S, Collins CM. Identification, cloning, expression, and purification of Francisella lpp3: an immunogenic lipoprotein. Microbiological Research. 165: 531-45. PMID 20006480 DOI: 10.1016/J.Micres.2009.11.004  0.431
2010 SHAFFER SA, SADILEK M, TURECEK F. ChemInform Abstract: Hypervalent Ammonium Radicals. Effects of Alkyl Groups and Aromatic Substituents. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199651047  0.533
2009 Nunn BL, Aker JR, Shaffer SA, Tsai S, Strzepek RF, Boyd PW, Freeman TL, Brittnacher M, Malmström L, Goodlett DR. Deciphering diatom biochemical pathways via whole-cell proteomics. Aquatic Microbial Ecology : International Journal. 55: 241-253. PMID 19829762 DOI: 10.3354/Ame01284  0.466
2009 Reimel BA, Pan S, May DH, Shaffer SA, Goodlett DR, McIntosh MW, Yerian LM, Bronner MP, Chen R, Brentnall TA. Proteomics on Fixed Tissue Specimens - A Review. Current Proteomics. 6: 63-69. PMID 19829741 DOI: 10.2174/157016409787847420  0.415
2009 Tsai YS, Scherl A, Shaw JL, MacKay CL, Shaffer SA, Langridge-Smith PR, Goodlett DR. Precursor ion independent algorithm for top-down shotgun proteomics. Journal of the American Society For Mass Spectrometry. 20: 2154-66. PMID 19773183 DOI: 10.1016/J.Jasms.2009.07.024  0.54
2009 Panchaud A, Scherl A, Shaffer SA, von Haller PD, Kulasekara HD, Miller SI, Goodlett DR. Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean. Analytical Chemistry. 81: 6481-8. PMID 19572557 DOI: 10.1021/Ac900888S  0.515
2009 Moore NH, Costa LG, Shaffer SA, Goodlett DR, Guizzetti M. Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation. Journal of Neurochemistry. 108: 891-908. PMID 19077055 DOI: 10.1111/j.1471-4159.2008.05836.x  0.425
2009 Hengel SM, Shaffer SA, Nunn BL, Goodlett DR. Tandem mass spectrometry investigation of ADP-ribosylated kemptide. Journal of the American Society For Mass Spectrometry. 20: 477-83. PMID 19070509 DOI: 10.1016/J.Jasms.2008.10.025  0.53
2009 Goo YA, Liu AY, Ryu S, Shaffer SA, Malmström L, Page L, Nguyen LT, Doneanu CE, Goodlett DR. Identification of secreted glycoproteins of human prostate and bladder stromal cells by comparative quantitative proteomics. The Prostate. 69: 49-61. PMID 18792917 DOI: 10.1002/Pros.20853  0.431
2008 Ryu S, Gallis B, Goo YA, Shaffer SA, Radulovic D, Goodlett DR. Comparison of a label-free quantitative proteomic method based on peptide ion current area to the isotope coded affinity tag method. Cancer Informatics. 6: 243-55. PMID 19259412 DOI: 10.4137/Cin.S385  0.475
2008 Gao Q, Xue S, Shaffer SA, Doneanu CE, Goodlett DR, Nelson SD. Minimize the detection of false positives by the software program DetectShift for 18O-labeled cross-linked peptide analysis. European Journal of Mass Spectrometry (Chichester, England). 14: 275-80. PMID 19023145 DOI: 10.1255/Ejms.939  0.428
2008 Singh P, Shaffer SA, Scherl A, Holman C, Pfuetzner RA, Larson Freeman TJ, Miller SI, Hernandez P, Appel RD, Goodlett DR. Characterization of protein cross-links via mass spectrometry and an open-modification search strategy. Analytical Chemistry. 80: 8799-806. PMID 18947195 DOI: 10.1021/Ac801646F  0.507
2008 Jones JW, Shaffer SA, Ernst RK, Goodlett DR, Turecek F. Determination of pyrophosphorylated forms of lipid A in Gram-negative bacteria using a multivaried mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12742-7. PMID 18753624 DOI: 10.1073/Pnas.0800445105  0.683
2008 Scherl A, Tsai YS, Shaffer SA, Goodlett DR. Increasing information from shotgun proteomic data by accounting for misassigned precursor ion masses. Proteomics. 8: 2791-7. PMID 18655048 DOI: 10.1002/Pmic.200800045  0.525
2008 Scherl A, Shaffer SA, Taylor GK, Hernandez P, Appel RD, Binz PA, Goodlett DR. On the benefits of acquiring peptide fragment ions at high measured mass accuracy. Journal of the American Society For Mass Spectrometry. 19: 891-901. PMID 18417358 DOI: 10.1016/J.Jasms.2008.02.005  0.516
2008 Rohmer L, Guina T, Chen J, Gallis B, Taylor GK, Shaffer SA, Miller SI, Brittnacher MJ, Goodlett DR. Determination and comparison of the Francisella tularensis subsp.novicida U112 proteome to other bacterial proteomes. Journal of Proteome Research. 7: 2016-24. PMID 18380474 DOI: 10.1021/Pr700760Z  0.48
2008 Kanistanon D, Hajjar AM, Pelletier MR, Gallagher LA, Kalhorn T, Shaffer SA, Goodlett DR, Rohmer L, Brittnacher MJ, Skerrett SJ, Ernst RK. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. Plos Pathogens. 4: e24. PMID 18266468 DOI: 10.1371/Journal.Ppat.0040024  0.409
2008 Scherl A, Shaffer SA, Taylor GK, Kulasekara HD, Miller SI, Goodlett DR. Genome-specific gas-phase fractionation strategy for improved shotgun proteomic profiling of proteotypic peptides. Analytical Chemistry. 80: 1182-91. PMID 18211032 DOI: 10.1021/Ac701680F  0.498
2007 Goo YA, Li Z, Pajkovic N, Shaffer S, Taylor G, Chen J, Campbell D, Arnstein L, Goodlett DR, van Breemen RB. Systematic investigation of lycopene effects in LNCaP cells by use of novel large-scale proteomic analysis software. Proteomics. Clinical Applications. 1: 513-523. PMID 20740054 DOI: 10.1002/Prca.200600511  0.515
2007 Foss EJ, Radulovic D, Shaffer SA, Ruderfer DM, Bedalov A, Goodlett DR, Kruglyak L. Genetic basis of proteome variation in yeast. Nature Genetics. 39: 1369-75. PMID 17952072 DOI: 10.1038/Ng.2007.22  0.448
2007 Prakash A, Piening B, Whiteaker J, Zhang H, Shaffer SA, Martin D, Hohmann L, Cooke K, Olson JM, Hansen S, Flory MR, Lee H, Watts J, Goodlett DR, Aebersold R, et al. Assessing bias in experiment design for large scale mass spectrometry-based quantitative proteomics. Molecular & Cellular Proteomics : McP. 6: 1741-8. PMID 17617667 DOI: 10.1074/Mcp.M600470-Mcp200  0.471
2007 Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, ... ... Shaffer SA, et al. Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biology. 8: R102. PMID 17550600 DOI: 10.1186/Gb-2007-8-6-R102  0.399
2007 Shaffer SA, Harvey MD, Goodlett DR, Ernst RK. Structural heterogeneity and environmentally regulated remodeling of Francisella tularensis subspecies novicida lipid A characterized by tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 18: 1080-92. PMID 17446084 DOI: 10.1016/J.Jasms.2007.03.008  0.511
2007 Trute M, Gallis B, Doneanu C, Shaffer S, Goodlett D, Gallagher E. Characterization of hepatic glutathione S-transferases in coho salmon (Oncorhynchus kisutch). Aquatic Toxicology (Amsterdam, Netherlands). 81: 126-36. PMID 17184855 DOI: 10.1016/J.Aquatox.2006.11.009  0.315
2006 Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjöstedt A, Edebro H, Forsman M, Byström M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infection and Immunity. 74: 6730-8. PMID 16982824 DOI: 10.1128/Iai.00934-06  0.399
2006 Nunn BL, Shaffer SA, Scherl A, Gallis B, Wu M, Miller SI, Goodlett DR. Comparison of a Salmonella typhimurium proteome defined by shotgun proteomics directly on an LTQ-FT and by proteome pre-fractionation on an LCQ-DUO. Briefings in Functional Genomics & Proteomics. 5: 154-68. PMID 16798750 DOI: 10.1093/Bfgp/Ell024  0.5
2006 Gao Q, Doneanu CE, Shaffer SA, Adman ET, Goodlett DR, Nelson SD. Identification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis. The Journal of Biological Chemistry. 281: 20404-17. PMID 16679316 DOI: 10.1074/Jbc.M601785200  0.476
2006 Gao Q, Xue S, Doneanu CE, Shaffer SA, Goodlett DR, Nelson SD. Pro-CrossLink. Software tool for protein cross-linking and mass spectrometry. Analytical Chemistry. 78: 2145-9. PMID 16579592 DOI: 10.1021/Ac051339C  0.535
1997 Shaffer SA, Wolken JK, Tureček F. Neutralization-reionization of alkenylammonium cations: An experimental and Ab initio study of intramolecular N-H ... C=C interactions in cations and hypervalent ammonium radicals Journal of the American Society For Mass Spectrometry. 8: 1111-1123. DOI: 10.1016/S1044-0305(97)00184-0  0.731
1997 Shaffer SA, Sadílek M, Tureček F, Hop CE. Protonation of isomeric methoxyhexenes. Effects of double bond⋯H+⋯OCH3 interaction International Journal of Mass Spectrometry and Ion Processes. 160: 137-155. DOI: 10.1016/S0168-1176(96)04480-1  0.644
1996 Shaffer SA, Sadílek M, Tureček F. Hypervalent ammonium radicals. Effects of alkyl groups and aromatic substituents Journal of Organic Chemistry. 61: 5234-5245. DOI: 10.1021/Jo960320U  0.573
1995 Nguyen VQ, Shaffer SA, Turecek F, Hop CECA. Franck-Condon Dominated Chemistry. Dissociations of Silicon-Centered Radicals Prepared by Femtosecond Reduction of Their Cations in the Gas Phase The Journal of Physical Chemistry. 99: 15454-15464. DOI: 10.1021/J100042A019  0.401
1995 Shaffer SA, Tureček F. Hydrogen bonding in transient bifunctional hypervalent radicals by neutralization-reionization mass spectrometry Journal of the American Society For Mass Spectrometry. 6: 1004-1018. DOI: 10.1016/1044-0305(95)00503-X  0.458
1994 Shaffer SA, Turecek F. Hydrogentrimethylammonium: A Marginally Stable Hypervalent Radical Journal of the American Chemical Society. 116: 8647-8653. DOI: 10.1021/Ja00098A026  0.402
1994 Kuhns DW, Tran TB, Shaffer SA, Turecek F. Methylthiomethyl Radical. A Variable-Time Neutralization-Reionization and ab Initio Study The Journal of Physical Chemistry. 98: 4845-4853. DOI: 10.1021/J100069A013  0.395
1993 Shaffer SA, Turecek F, Cerny RL. The (dimethylamino)methyl radical. A neutralization-reionization and ab initio study Journal of the American Chemical Society. 115: 12117-12124. DOI: 10.1021/Ja00078A058  0.418
1992 Turecek F, Gu M, Shaffer SA. Novel tandem quadrupole-acceleration-deceleration mass spectrometer for neutralization-reionization studies Journal of the American Society For Mass Spectrometry. 3: 493-501. DOI: 10.1016/1044-0305(92)85026-G  0.627
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