Alexander Heckel - Publications

Affiliations: 
Goethe University, Frankfurt am Main 
Area:
optochemical biology

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klimek R, Donlin-Asp PG, Polisseni C, Hanff V, Schuman EM, Heckel A. Visible light-activatable Q-dye molecular beacons for long-term mRNA monitoring in neurons. Chemical Communications (Cambridge, England). 57: 12683-12686. PMID 34780585 DOI: 10.1039/d1cc05664f  1
2021 Blümler A, Schwalbe H, Heckel A. Solid-Phase-Supported Chemoenzymatic Synthesis of a Light-Activatable tRNA Derivative. Angewandte Chemie (International Ed. in English). PMID 34738704 DOI: 10.1002/anie.202111613  1
2021 Hohmann KF, Blümler A, Heckel A, Fürtig B. The RNA chaperone StpA enables fast RNA refolding by destabilization of mutually exclusive base pairs within competing secondary structure elements. Nucleic Acids Research. PMID 34614185 DOI: 10.1093/nar/gkab876  1
2021 Hermanns V, Scheurer M, Kersten NF, Abdellaoui C, Wachtveitl J, Dreuw A, Heckel A. Re-Thinking Uncaging: A New Antiaromatic Photocage Driven by a Gain of Resonance Energy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34363415 DOI: 10.1002/chem.202102351  1
2021 Müller P, Sahlbach M, Gasper S, Mayer G, Müller J, Pötzsch B, Heckel A. Controlling Coagulation in Blood with Red Light. Angewandte Chemie (International Ed. in English). PMID 34293228 DOI: 10.1002/anie.202108468  1
2021 Malik H, Halbritter T, Heckel A, Gopakumar TG. Light-Induced Quantitative and Electrical-Field-Induced Barrierless Switching of Spiropyran Derivative on Graphite Surface. The Journal of Physical Chemistry Letters. 5463-5468. PMID 34085521 DOI: 10.1021/acs.jpclett.1c01186  1
2021 Wachtveitl J, Kaiser C, Halbritter T, Heckel A. Proton-transfer Dynamics of Photoacidic Merocyanines in Aqueous Solution. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33929051 DOI: 10.1002/chem.202100168  1
2021 Grün JT, Blümler A, Burkhart I, Wirmer-Bartoschek J, Heckel A, Schwalbe H. Unraveling the Kinetics of Spare-Tire DNA G-Quadruplex Folding. Journal of the American Chemical Society. PMID 33872503 DOI: 10.1021/jacs.1c01089  1
2021 Donlin-Asp PG, Polisseni C, Klimek R, Heckel A, Schuman EM. Differential regulation of local mRNA dynamics and translation following long-term potentiation and depression. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33771924 DOI: 10.1073/pnas.2017578118  1
2021 Harkness RW, Hennecker C, Grün JT, Blümler A, Heckel A, Schwalbe H, Mittermaier AK. Parallel reaction pathways accelerate folding of a guanine quadruplex. Nucleic Acids Research. PMID 33469659 DOI: 10.1093/nar/gkaa1286  1
2020 Klimek R, Wang M, McKenney VR, Schuman EM, Heckel A. Photo-tethered molecular beacons for superior light-induction. Chemical Communications (Cambridge, England). PMID 33346255 DOI: 10.1039/d0cc06704k  1
2020 Becker Y, Roth S, Scheurer M, Jakob A, Gacek D, Dreuw A, Wachtveitl J, Heckel A. Selective Modification for Red-Shifted Excitability - a Small Change in Structure, a Huge Change in the Photochemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32955154 DOI: 10.1002/Chem.202003672  1
2020 de Mos J, Jakob A, Becker-Baldus J, Heckel A, Glaubitz C. Light-induced uncaging for time-resolved observations of biochemical reactions by MAS NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32240561 DOI: 10.1002/chem.202000770  1
2020 Fürtig B, Oberhauser EM, Zetzsche H, Klötzner DP, Heckel A, Schwalbe H. Refolding through a Linear Transition State Enables Fast Temperature Adaptation of a Translational Riboswitch. Biochemistry. PMID 32134253 DOI: 10.1021/Acs.Biochem.9B01044  1
2019 Grün JT, Hennecker C, Klötzner DP, Harkness The Fifth RW, Bessi I, Heckel A, Mittermaier AK, Schwalbe H. Conformational Dynamics of Strand Register Shifts in DNA G-quadruplexes. Journal of the American Chemical Society. PMID 31815451 DOI: 10.1021/Jacs.9B10367  1
2019 Grebenovsky N, Luma L, Müller P, Heckel A. Introducing LNAzo: More Rigidity for Improved Photocontrol of Oligonucleotide Hybridization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31386225 DOI: 10.1002/chem.201903240  1
2019 Müller P, Seyfried P, Frühauf A, Heckel A. Phosphodiester photo-tethers for the (multi-)cyclic conformational caging of oligonucleotides. Methods in Enzymology. 624: 89-111. PMID 31370937 DOI: 10.1016/bs.mie.2019.04.019  1
2019 Möbius K, Kazemi S, Güntert P, Jakob A, Heckel A, Becker-Baldus J, Glaubitz C. Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR. Scientific Reports. 9: 3995. PMID 30850624 DOI: 10.1038/s41598-019-40264-8  1
2018 Lotz TS, Halbritter T, Kaiser C, Rudolph MM, Kraus L, Groher F, Steinwand S, Wachtveitl J, Heckel A, Suess B. A light-responsive RNA aptamer for an azobenzene derivative. Nucleic Acids Research. PMID 30517682 DOI: 10.1093/Nar/Gky1225  1
2018 Erlenbach N, Grünewald C, Krstic B, Heckel A, Prisner TF. 'End-to-End' stacking of small dsRNA. Rna (New York, N.Y.). PMID 30404925 DOI: 10.1261/Rna.068130.118  0.01
2018 Yadav K, Mahapatra S, Halbritter T, Heckel A, Gopakumar TG. Low-Threshold Reversible Electron-Induced and Selective Photoinduced Switching of Azobenzene Derivatives under Ambient Conditions. The Journal of Physical Chemistry Letters. 6326-6333. PMID 30346779 DOI: 10.1021/Acs.Jpclett.8B02875  1
2018 Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker H, Stelzl L, Hummer G, Schwalbe H, Heckel A. Optimal destabilization of DNA double strands by single-nucleobase caging. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30199112 DOI: 10.1002/Chem.201804040  1
2018 Kahlstatt J, Reiß P, Halbritter T, Essen LO, Koert U, Heckel A. A light-triggered transmembrane porin. Chemical Communications (Cambridge, England). 54: 9623-9626. PMID 30095845 DOI: 10.1039/c8cc05221b  0.01
2018 Schwalbe H, Keyhani S, Goldau T, Blümler A, Heckel A. Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy. Angewandte Chemie (International Ed. in English). PMID 30007102 DOI: 10.1002/Anie.201807125  1
2018 Reinfelds M, von Cosel J, Falahati K, Hamerla C, Slanina T, Heckel A, Burghardt I. A new photocage derived from fluorene. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29889321 DOI: 10.1002/Chem.201802390  1
2018 Becker Y, Unger E, Fichte MAH, Gacek DA, Dreuw A, Wachtveitl J, Walla PJ, Heckel A. A red-shifted two-photon-only caging group for three-dimensional photorelease. Chemical Science. 9: 2797-2802. PMID 29732066 DOI: 10.1039/C7Sc05182D  1
2018 Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H. Life times of metastable states guide regulatory signaling in transcriptional riboswitches. Nature Communications. 9: 944. PMID 29507289 DOI: 10.1038/S41467-018-03375-W  1
2018 Hammer CA, Falahati K, Jakob A, Klimek R, Burghardt I, Heckel A, Wachtveitl J. Sensitized Two-Photon Activation of Coumarin Photocages. The Journal of Physical Chemistry Letters. 1448-1453. PMID 29498870 DOI: 10.1021/Acs.Jpclett.7B03364  1
2018 Grebenovsky N, Goldau T, Bolte M, Heckel A. Light Regulation of DNA Minicircle Dimerization by Utilizing Azobenzene C-Nucleosides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29418024 DOI: 10.1002/chem.201706003  1
2017 Kern-Michler D, Neumann C, Mielke N, van Wilderen LJGW, Reinfelds M, von Cosel J, Santoro F, Heckel A, Burghardt I, Bredenbeck J. Controlling photochemistry via isotopomers and IR preexcitation. Journal of the American Chemical Society. PMID 29182322 DOI: 10.1021/Jacs.7B08723  1
2017 Klötzner DP, Klehs K, Heilemann M, Heckel A. A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy. Chemical Communications (Cambridge, England). PMID 28825088 DOI: 10.1039/c7cc04996j  1
2017 Halbritter T, Kaiser C, Wachtveitl J, Heckel A. A Pyridin-Spiropyran Derivative as Persistent, Reversible Photoacid in Water. The Journal of Organic Chemistry. PMID 28686024 DOI: 10.1021/Acs.Joc.7B01268  1
2017 Weyel XMM, Fichte MAH, Heckel A. A Two-Photon-Photocleavable Linker for Triggering Light-Induced Strand Breaks in Oligonucleotides. Acs Chemical Biology. PMID 28678467 DOI: 10.1021/acschembio.7b00367  1
2017 Lucas T, Schäfer F, Müller P, Eming SA, Heckel A, Dimmeler S. Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice. Nature Communications. 8: 15162. PMID 28462946 DOI: 10.1038/ncomms15162  1
2017 Meyer A, Slanina T, Heckel A, König B. Metal ion coupled consecutive photoinduced electron transfer generates strong reduction potentials from visible light. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28429580 DOI: 10.1002/Chem.201701665  1
2017 Sambandan S, Akbalik G, Kochen L, Rinne J, Kahlstatt J, Glock C, Tushev G, Alvarez-Castelao B, Heckel A, Schuman EM. Activity-dependent spatially localized miRNA maturation in neuronal dendrites. Science (New York, N.Y.). 355: 634-637. PMID 28183980 DOI: 10.1126/Science.Aaf8995  1
2017 Junek S, Holzmeister S, Fichte M, Heckel A, Wendt O, Rapp G. Manipulation of Neurons with Precisely Controlled Illumination in Space and Time Biophysical Journal. 112: 284a. DOI: 10.1016/J.BPJ.2016.11.1539  0.01
2017 Kaiser C, Halbritter T, Heckel A, Wachtveitl J. Thermal, Photochromic and Dynamic Properties of Water-Soluble Spiropyrans Chemistryselect. 2: 4111-4123. DOI: 10.1002/SLCT.201700868  0.01
2016 Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A. Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides. Angewandte Chemie (International Ed. in English). PMID 27897376 DOI: 10.1002/Anie.201610025  1
2016 Fichte MA, Weyel XM, Junek S, Schäfer F, Herbivo C, Goeldner M, Specht A, Wachtveitl J, Heckel A. Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging. Angewandte Chemie (International Ed. in English). PMID 27294300 DOI: 10.1002/Anie.201603281  1
2016 Thevarpadam J, Bessi I, Binas O, Gonçalves DP, Slavov C, Jonker HR, Richter C, Wachtveitl J, Schwalbe H, Heckel A. Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif. Angewandte Chemie (International Ed. in English). 55: 2738-42. PMID 26805928 DOI: 10.1002/Anie.201510269  1
2016 Thevarpadam J, Bessi I, Binas O, Gonçalves DPN, Slavov C, Jonker HRA, Richter C, Wachtveitl J, Schwalbe H, Heckel A. Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif Angewandte Chemie - International Edition. 55: 2738-2742. DOI: 10.1002/anie.201510269  1
2015 Civit L, Pinto A, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G. Sensitive detection of cancer cells using light-mediated apta-PCR. Methods (San Diego, Calif.). PMID 26615953 DOI: 10.1016/J.Ymeth.2015.11.018  1
2015 Goldau T, Murayama K, Brieke C, Asanuma H, Heckel A. Azobenzene C-Nucleosides for Photocontrolled Hybridization of DNA at Room Temperature. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26489532 DOI: 10.1002/chem.201503303  1
2015 Slanina T, Šebej P, Heckel A, Givens RS, Klán P. Caged Fluoride: Photochemistry and Applications of 4-Hydroxyphenacyl Fluoride. Organic Letters. 17: 4814-7. PMID 26378924 DOI: 10.1021/Acs.Orglett.5B02374  1
2015 Steinwand S, Halbritter T, Rastädter D, Ortiz-Sánchez JM, Burghardt I, Heckel A, Wachtveitl J. Ultrafast Spectroscopy of Hydroxy-Substituted Azobenzenes in Water. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 15720-31. PMID 26345463 DOI: 10.1002/Chem.201501863  1
2015 Friedrich F, Klehs K, Fichte MA, Junek S, Heilemann M, Heckel A. A two-photon activatable amino acid linker for the induction of fluorescence. Chemical Communications (Cambridge, England). 51: 15382-5. PMID 26343765 DOI: 10.1039/c5cc05700k  1
2015 Mondal P, Biswas M, Goldau T, Heckel A, Burghardt I. In Search of an Efficient Photoswitch for Functional RNA: Design Principles from a Microscopic Analysis of Azobenzene-linker-RNA Dynamics with Different Linkers. The Journal of Physical Chemistry. B. 119: 11275-86. PMID 26125118 DOI: 10.1021/Acs.Jpcb.5B03118  1
2015 Özçoban C, Halbritter T, Steinwand S, Herzig LM, Kohl-Landgraf J, Askari N, Groher F, Fürtig B, Richter C, Schwalbe H, Suess B, Wachtveitl J, Heckel A. Water-soluble Py-BIPS spiropyrans as photoswitches for biological applications. Organic Letters. 17: 1517-20. PMID 25760939 DOI: 10.1021/Acs.Orglett.5B00397  1
2015 Goldau T, Murayama K, Brieke C, Steinwand S, Mondal P, Biswas M, Burghardt I, Wachtveitl J, Asanuma H, Heckel A. Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 2845-54. PMID 25537843 DOI: 10.1002/Chem.201405840  1
2015 Spille JH, Kaminski TP, Scherer K, Rinne JS, Heckel A, Kubitscheck U. Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking Nucleic Acids Research. 43: e14. PMID 25414330 DOI: 10.1093/nar/gku1194  1
2014 Fürtig B, Reining A, Sochor F, Oberhauser EM, Heckel A, Schwalbe H. Characterization of conformational dynamics of bistable RNA by equilibrium and non-equilibrium NMR. Current Protocols in Nucleic Acid Chemistry. 55: 11.13.1-16. PMID 25631532 DOI: 10.1002/0471142700.Nc1113S55  1
2014 Raulf A, Spahn CK, Zessin PJ, Finan K, Bernhardt S, Heckel A, Heilemann M. Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data file. Rsc Advances. 4: 30462-30466. PMID 25580242 DOI: 10.1039/c4ra01027b  1
2014 Rodrigues-Correia A, Knapp-Bühle D, Engels JW, Heckel A. Selective uncaging of DNA through reaction rate selectivity. Organic Letters. 16: 5128-31. PMID 25232905 DOI: 10.1021/ol502478g  1
2014 Rodrigues-Correia A, Seyfried P, Heckel A. Wavelength-selective uncaging of oligonucleotides. Current Protocols in Nucleic Acid Chemistry. 57: 6.11.1-32. PMID 24961722 DOI: 10.1002/0471142700.nc0611s57  1
2014 Gatterdam V, Ramadass R, Stoess T, Fichte MA, Wachtveitl J, Heckel A, Tampé R. Three-dimensional protein networks assembled by two-photon activation. Angewandte Chemie (International Ed. in English). 53: 5680-4. PMID 24729568 DOI: 10.1002/Anie.201309930  1
2014 Steinert HS, Schäfer F, Jonker HR, Heckel A, Schwalbe H. Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability. Angewandte Chemie (International Ed. in English). 53: 1072-5. PMID 24339185 DOI: 10.1002/Anie.201307852  1
2014 Seven I, Weinrich T, Gränz M, Grünewald C, Brüß S, Krstić I, Prisner TF, Heckel A, Göbel MW. Photolabile Protecting Groups for Nitroxide Spin Labels European Journal of Organic Chemistry. 2014: 4037-4043. DOI: 10.1002/Ejoc.201301692  0.01
2014 Gatterdam V, Ramadass R, Stoess T, Fichte MAH, Wachtveitl J, Heckel A, Tampé R. Back Cover: Three-Dimensional Protein Networks Assembled by Two-Photon Activation (Angew. Chem. Int. Ed. 22/2014) Angewandte Chemie International Edition. 53: 5712-5712. DOI: 10.1002/Anie.201401149  0.01
2014 Gatterdam V, Ramadass R, Stoess T, Fichte MAH, Wachtveitl J, Heckel A, Tampé R. Rücktitelbild: Dreidimensionale Proteinnetzwerke durch Zwei-Photonen- Aktivierung (Angew. Chem. 22/2014) Angewandte Chemie. 126: 5820-5820. DOI: 10.1002/Ange.201401149  0.01
2014 Gatterdam V, Ramadass R, Stoess T, Fichte MAH, Wachtveitl J, Heckel A, Tampé R. Dreidimensionale Proteinnetzwerke durch Zwei-Photonen- Aktivierung Angewandte Chemie. 126: 5787-5791. DOI: 10.1002/Ange.201309930  0.01
2013 Schäfer F, Wagner J, Knau A, Dimmeler S, Heckel A. Regulating angiogenesis with light-inducible AntimiRs. Angewandte Chemie (International Ed. in English). 52: 13558-61. PMID 24174377 DOI: 10.1002/anie.201307502  1
2013 Rohrbach F, Schäfer F, Fichte MA, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. Aptamer-guided caging for selective masking of protein domains. Angewandte Chemie (International Ed. in English). 52: 11912-5. PMID 24127310 DOI: 10.1002/Anie.201306686  1
2013 Brieke C, Heckel A. Spiropyran photoswitches in the context of DNA: synthesis and photochromic properties. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 15726-34. PMID 24115210 DOI: 10.1002/chem.201302640  1
2013 Rodrigues-Correia A, Weyel XM, Heckel A. Four levels of wavelength-selective uncaging for oligonucleotides. Organic Letters. 15: 5500-3. PMID 24111849 DOI: 10.1021/ol402657j  1
2013 Rinne JS, Kaminski TP, Kubitscheck U, Heckel A. Light-inducible molecular beacons for spatio-temporally highly defined activation Chemical Communications. 49: 5375-5377. PMID 23652644 DOI: 10.1039/c3cc42420k  1
2013 Rohrbach F, Schäfer F, Fichte MAH, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. Inside Back Cover: Aptamer-Guided Caging for Selective Masking of Protein Domains (Angew. Chem. Int. Ed. 45/2013) Angewandte Chemie International Edition. 52: 11941-11941. DOI: 10.1002/Anie.201308371  0.01
2013 Rohrbach F, Schäfer F, Fichte MAH, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. Innenrücktitelbild: Aptamerbasiertes Caging zur selektiven Maskierung von Proteindomänen (Angew. Chem. 45/2013) Angewandte Chemie. 125: 12159-12159. DOI: 10.1002/Ange.201308371  0.01
2013 Schäfer F, Wagner J, Knau A, Dimmeler S, Heckel A. Regulation der Angiogenese durch lichtinduzierbare AntimiRs Angewandte Chemie. 125: 13801-13805. DOI: 10.1002/ANGE.201307502  0.01
2013 Rohrbach F, Schäfer F, Fichte MAH, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. Aptamerbasiertes Caging zur selektiven Maskierung von Proteindomänen Angewandte Chemie. 125: 12129-12132. DOI: 10.1002/Ange.201306686  0.01
2012 Brieke C, Rohrbach F, Gottschalk A, Mayer G, Heckel A. Light-controlled tools. Angewandte Chemie (International Ed. in English). 51: 8446-76. PMID 22829531 DOI: 10.1002/Anie.201202134  1
2012 Kohl-Landgraf J, Braun M, Özçoban C, Gonçalves DP, Heckel A, Wachtveitl J. Ultrafast dynamics of a spiropyran in water. Journal of the American Chemical Society. 134: 14070-7. PMID 22803805 DOI: 10.1021/Ja304395K  1
2012 Dreuw A, Polkehn MA, Binder R, Heckel A, Knippenberg S. Computational design of improved two-photon active caging compounds based on nitrodibenzofuran. Journal of Computational Chemistry. 33: 1797-805. PMID 22618511 DOI: 10.1002/Jcc.23007  1
2012 Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R. Caged glutathione - triggering protein interaction by light. Angewandte Chemie (International Ed. in English). 51: 3960-3. PMID 22392772 DOI: 10.1002/anie.201108073  1
2012 Wurm JP, Griese M, Bahr U, Held M, Heckel A, Karas M, Soppa J, Wöhnert J. Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. Rna (New York, N.Y.). 18: 412-20. PMID 22274954 DOI: 10.1261/Rna.028498.111  1
2012 Joshi KB, Vlachos A, Mikat V, Deller T, Heckel A. Light-activatable molecular beacons with a caged loop sequence. Chemical Communications (Cambridge, England). 48: 2746-8. PMID 22159276 DOI: 10.1039/c2cc16654b  1
2012 Pinto A, Lennarz S, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G. Functional detection of proteins by caged aptamers. Acs Chemical Biology. 7: 360-6. PMID 22070344 DOI: 10.1021/Cb2003835  1
2012 Wulffen B, Buff MC, Pofahl M, Mayer G, Heckel A. Caged glucosamine-6-phosphate for the light-control of riboswitch activity. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 11: 489-92. PMID 22005771 DOI: 10.1039/C1Pp05242J  1
2012 Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R. Inside Cover: Caged Glutathione - Triggering Protein Interaction by Light (Angew. Chem. Int. Ed. 16/2012) Angewandte Chemie International Edition. 51: 3726-3726. DOI: 10.1002/ANIE.201201327  0.01
2012 Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R. Innentitelbild: Photoaktivierbares Glutathion - lichtgesteuerte Proteinwechselwirkung (Angew. Chem. 16/2012) Angewandte Chemie. 124: 3788-3788. DOI: 10.1002/ANGE.201201327  0.01
2012 Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R. Photoaktivierbares Glutathion - lichtgesteuerte Proteinwechselwirkung Angewandte Chemie. 124: 4027-4030. DOI: 10.1002/ANGE.201108073  0.01
2011 Menge C, Heckel A. Coumarin-caged dG for improved wavelength-selective uncaging of DNA. Organic Letters. 13: 4620-3. PMID 21834506 DOI: 10.1021/Ol201842X  1
2011 Schmidt TL, Koeppel MB, Thevarpadam J, Gonçalves DP, Heckel A. A light trigger for DNA nanotechnology. Small (Weinheim An Der Bergstrasse, Germany). 7: 2163-7. PMID 21638782 DOI: 10.1002/Smll.201100182  1
2011 Friedrich F, Heckel A. Photon cascade with clip-on fluorophores. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 12: 2073-5. PMID 21567707 DOI: 10.1002/Cphc.201100295  1
2011 Schmidt TL, Heckel A. Construction of a structurally defined double-stranded DNA catenane. Nano Letters. 11: 1739-42. PMID 21410245 DOI: 10.1021/Nl200303M  1
2011 Schäfer F, Joshi KB, Fichte MAH, MacK T, Wachtveitl J, Heckel A. Wavelength-selective uncaging of da and dC residues Organic Letters. 13: 1450-1453. PMID 21341754 DOI: 10.1021/Ol200141V  1
2011 Meyer B, Wurm JP, Kötter P, Leisegang MS, Schilling V, Buchhaupt M, Held M, Bahr U, Karas M, Heckel A, Bohnsack MT, Wöhnert J, Entian KD. The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. Nucleic Acids Research. 39: 1526-37. PMID 20972225 DOI: 10.1093/Nar/Gkq931  1
2011 Rodrigues-Correia A, Koeppel MB, Schäfer F, Joshi KB, MacK T, Heckel A. Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides Analytical and Bioanalytical Chemistry. 399: 441-447. PMID 20953770 DOI: 10.1007/S00216-010-4274-7  1
2010 Gonçalves DP, Schmidt TL, Koeppel MB, Heckel A. DNA minicircles connected via G-quadruplex interaction modules. Small (Weinheim An Der Bergstrasse, Germany). 6: 1347-52. PMID 20486229 DOI: 10.1002/Smll.201000318  1
2010 Ackermann D, Rasched G, Verma S, Schmidt TL, Heckel A, Famulok M. Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chemical Communications (Cambridge, England). 46: 4154-6. PMID 20473448 DOI: 10.1039/C0Cc00390E  1
2010 Kumar J, Sreeramulu S, Schmidt TL, Richter C, Vonck J, Heckel A, Glaubitz C, Schwalbe H. Prion protein amyloid formation involves structural rearrangements in the C-terminal domain. Chembiochem : a European Journal of Chemical Biology. 11: 1208-13. PMID 20458726 DOI: 10.1002/Cbic.201000076  1
2010 Ackermann D, Schmidt TL, Hannam JS, Purohit CS, Heckel A, Famulok M. A double-stranded DNA rotaxane. Nature Nanotechnology. 5: 436-42. PMID 20400967 DOI: 10.1038/Nnano.2010.65  1
2010 Wurm JP, Meyer B, Bahr U, Held M, Frolow O, Kötter P, Engels JW, Heckel A, Karas M, Entian KD, Wöhnert J. The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. Nucleic Acids Research. 38: 2387-98. PMID 20047967 DOI: 10.1093/Nar/Gkp1189  1
2010 Buff MC, Schäfer F, Wulffen B, Müller J, Pötzsch B, Heckel A, Mayer G. Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency. Nucleic Acids Research. 38: 2111-8. PMID 20007153 DOI: 10.1093/nar/gkp1148  1
2009 Mayer G, Lohberger A, Butzen S, Pofahl M, Blind M, Heckel A. From selection to caged aptamers: identification of light-dependent ssDNA aptamers targeting cytohesin. Bioorganic & Medicinal Chemistry Letters. 19: 6561-4. PMID 19854646 DOI: 10.1016/j.bmcl.2009.10.032  1
2009 Hoffmann J, Schmidt TL, Heckel A, Brutschy B. Probing the limits of liquid droplet laser desorption mass spectrometry in the analysis of oligonucleotides and nucleic acids. Rapid Communications in Mass Spectrometry : Rcm. 23: 2176-80. PMID 19530153 DOI: 10.1002/rcm.4129  1
2009 Schmidt TL, Heckel A. Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions. Small (Weinheim An Der Bergstrasse, Germany). 5: 1517-20. PMID 19360724 DOI: 10.1002/smll.200900147  1
2009 Jayapal P, Mayer G, Heckel A, Wennmohs F. Structure-activity relationships of a caged thrombin binding DNA aptamer: insight gained from molecular dynamics simulation studies. Journal of Structural Biology. 166: 241-50. PMID 19285137 DOI: 10.1016/j.jsb.2009.01.010  1
2009 Mayer G, Müller J, Mack T, Freitag DF, Höver T, Pötzsch B, Heckel A. Differential regulation of protein subdomain activity with caged bivalent ligands. Chembiochem : a European Journal of Chemical Biology. 10: 654-7. PMID 19189364 DOI: 10.1002/cbic.200800814  1
2009 Buff M, Mack T, Heckel A. Light-Activatable Nucleic Acids 'Caged' at the Nucleobases Chimia International Journal For Chemistry. 63: 261-264. DOI: 10.2533/CHIMIA.2009.261  0.01
2008 Heckel A, Famulok M. Building objects from nucleic acids for a nanometer world. Biochimie. 90: 1096-107. PMID 18316041 DOI: 10.1016/J.Biochi.2008.02.004  1
2008 Nandi CK, Parui PP, Schmidt TL, Heckel A, Brutschy B. Binding of hairpin polyamides to DNA studied by fluorescence correlation spectroscopy for DNA nanoarchitectures. Analytical and Bioanalytical Chemistry. 390: 1595-603. PMID 18224303 DOI: 10.1007/S00216-008-1852-Z  1
2008 Rasched G, Ackermann D, Schmidt TL, Broekmann P, Heckel A, Famulok M. DNA minicircles with gaps for versatile functionalization. Angewandte Chemie (International Ed. in English). 47: 967-70. PMID 18058876 DOI: 10.1002/Anie.200704004  1
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M, Mayer G, Kuhn N. Cover Picture: DNA Minicircles with Gaps for Versatile Functionalization / Construction of DNA Architectures with RNA Hairpins (Angew. Chem. Int. Ed. 5/2008) Angewandte Chemie International Edition. 47: 803-803. DOI: 10.1002/Anie.200890008  0.01
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M, Mayer G, Kuhn N. Titelbild: DNA-Ringe mit Einzelstrangdomänen zur vielseitigen Funktionalisierung / Aufbau von DNA-Architekturen mit RNA-Haarnadelschleifen (Angew. Chem. 5/2008) Angewandte Chemie. 120: 815-815. DOI: 10.1002/Ange.200890009  0.01
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M. DNA-Ringe mit Einzelstrangdomänen zur vielseitigen Funktionalisierung Angewandte Chemie. 120: 981-984. DOI: 10.1002/Ange.200704004  0.01
2007 Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB. Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron. 63: 6146-6151. PMID 18596841 DOI: 10.1016/J.Tet.2007.03.041  1
2007 Heckel A. Nucleobase-caged phosphoramidites for oligonucleotide synthesis. Current Protocols in Nucleic Acid Chemistry. Unit 1.17. PMID 18428965 DOI: 10.1002/0471142700.Nc0117S29  0.01
2007 Mikat V, Heckel A. Light-dependent RNA interference with nucleobase-caged siRNAs. Rna (New York, N.Y.). 13: 2341-7. PMID 17951332 DOI: 10.1261/Rna.753407  1
2007 Schmidt TL, Nandi CK, Rasched G, Parui PP, Brutschy B, Famulok M, Heckel A. Polyamide struts for DNA architectures. Angewandte Chemie (International Ed. in English). 46: 4382-4. PMID 17458850 DOI: 10.1002/Anie.200700469  1
2007 Mayer G, Heckel A. Light-stimulated patterning of cells. Chembiochem : a European Journal of Chemical Biology. 8: 857-8. PMID 17440910 DOI: 10.1002/Cbic.200700093  1
2007 Morgner N, Barth HD, Schmidt TL, Heckel A, Scheffer U, Göbel M, Fucini P, Brutschy B. Detecting specific ligand binding to nucleic acids: A test for ultrasoft laser mass spectrometry Zeitschrift Fur Physikalische Chemie. 221: 689-704. DOI: 10.1524/Zpch.2007.221.5.689  1
2007 Schmidt T, Nandi C, Rasched G, Parui P, Brutschy B, Famulok M, Heckel A. Polyamid-Stützen für DNA-Architekturen Angewandte Chemie. 119: 4460-4462. DOI: 10.1002/Ange.200700469  0.01
2007 Seebach D, Beck AK, Heckel A. TADDOL and its derivatives - Our dream of universal chiral auxiliaries Essays in Contemporary Chemistry: From Molecular Structure Towards Biology. 283-306. DOI: 10.1002/9783906390451.ch7  1
2006 Heckel A, Buff MC, Raddatz MS, Müller J, Pötzsch B, Mayer G. An anticoagulant with light-triggered antidote activity. Angewandte Chemie (International Ed. in English). 45: 6748-50. PMID 16983715 DOI: 10.1002/Anie.200602346  1
2006 Mayer G, Heckel A. Biologically active molecules with a "light switch". Angewandte Chemie (International Ed. in English). 45: 4900-21. PMID 16826610 DOI: 10.1002/Anie.200600387  1
2006 Heckel A, Buff MCR, Raddatz ML, Müller J, Pötzsch B, Mayer G. Ein Antikoagulans mit photoaktivierbarer Antidotaktivität Angewandte Chemie. 118: 6900-6902. DOI: 10.1002/Ange.200602346  0.01
2006 Mayer G, Heckel A. Biologisch aktive Moleküle mit “Lichtschalter” Angewandte Chemie. 118: 5020-5042. DOI: 10.1002/Ange.200600387  0.01
2005 Mayer G, Kröck L, Mikat V, Engeser M, Heckel A. Light-induced formation of G-quadruplex DNA secondary structures. Chembiochem : a European Journal of Chemical Biology. 6: 1966-70. PMID 16178038 DOI: 10.1002/Cbic.200500198  1
2005 Fusz S, Eisenführ A, Srivatsan SG, Heckel A, Famulok M. A ribozyme for the aldol reaction. Chemistry & Biology. 12: 941-50. PMID 16125106 DOI: 10.1016/J.Chembiol.2005.06.008  1
2005 Heckel A, Mayer G. Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases. Journal of the American Chemical Society. 127: 822-3. PMID 15656605 DOI: 10.1021/Ja043285E  1
2005 Kröck L, Heckel A. Photoinduced transcription by using temporarily mismatched caged oligonucleotides. Angewandte Chemie (International Ed. in English). 44: 471-3. PMID 15624132 DOI: 10.1002/Anie.200461779  1
2005 Mayer G, Kröck L, Mikat V, Engeser M, Heckel A. Cover Picture: Light-Induced Formation of G-Quadruplex DNA Secondary Structures (ChemBioChem 11/2005) Chembiochem. 6: 1913-1913. DOI: 10.1002/Cbic.200590036  0.01
2004 Heckel A. A new DNA analogue with expanded size and scope. Chembiochem : a European Journal of Chemical Biology. 5: 765-7. PMID 15174157 DOI: 10.1002/Cbic.200400001  0.01
2004 Edelson BS, Best TP, Olenyuk B, Nickols NG, Doss RM, Foister S, Heckel A, Dervan PB. Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Research. 32: 2802-18. PMID 15155849 DOI: 10.1093/Nar/Gkh609  1
2004 Kröck L, Heckel A. Lichtinduzierte Transkription mit vorübergehend fehlgepaarten Oligonucleotiden Angewandte Chemie. 117: 475-477. DOI: 10.1002/Ange.200461779  0.01
2003 Heckel A, Dervan PB. U-pin polyamide motif for recognition of the DNA minor groove. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3353-66. PMID 12866079 DOI: 10.1002/Chem.200304784  1
2003 Heckel A, Dervan PB. Cover Picture: U-Pin Polyamide Motif for Recognition of the DNA Minor Groove (Chem. Eur. J. 14/2003) Chemistry - a European Journal. 9: 3173-3173. DOI: 10.1002/Chem.200390233  1
2002 Heckel A, Seebach D. Preparation and characterization of TADDOLs immobilized on hydrophobic controlled-pore-glass silica gel and their use in enantioselective heterogeneous catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 559-72. PMID 11855704 DOI: 10.1002/1521-3765(20020201)8:3<559::Aid-Chem559>3.0.Co;2-1  1
2002 Heckel A, Seebach D. Enantioselective Heterogeneous Epoxidation and Hetero-Diels-Alder Reaction with Mn- and Cr-salen Complexes Immobilized on Silica Gel by Radical Grafting Helvetica Chimica Acta. 85: 913. DOI: 10.1002/1522-2675(200203)85:3<913::Aid-Hlca913>3.0.Co;2-U  0.01
2001 Seebach D, Beck AK, Heckel A. TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries. Angewandte Chemie (International Ed. in English). 40: 92-138. PMID 11169693 DOI: 10.1002/1521-3773(20010105)40:1<92::Aid-Anie92>3.0.Co;2-K  1
2001 Seebach D, Beck AK, Heckel A. Cover Picture. Angewandte Chemie (International Ed. in English). 40: 1. PMID 11169690 DOI: 10.1002/1521-3773(20010105)40:1<1::AID-ANIE1>3.0.CO;2-F  1
2001 Seebach D, Beck AK, Heckel A. TADDOLe, ihre Derivate und Analoga – vielseitige chirale Hilfsstoffe Angewandte Chemie. 113: 96-142. DOI: 10.1002/1521-3757(20010105)113:1<96::Aid-Ange96>3.0.Co;2-B  0.01
2000 Heckel A, Seebach D. Immobilization of TADDOL with a High Degree of Loading on Porous Silica Gel and First Applications in Enantioselective Catalysis. Angewandte Chemie (International Ed. in English). 39: 163-165. PMID 10649361 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<163::Aid-Anie163>3.0.Co;2-J  1
2000 Heckel A, Seebach D. Verankerung von TADDOL auf porösem Kieselgel mit hoher Beladung und erste Anwendungen in der enantioselektiven Katalyse Angewandte Chemie. 112: 165-167. DOI: 10.1002/(Sici)1521-3757(20000103)112:1<165::Aid-Ange165>3.0.Co;2-V  0.01
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