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Donald Gagne, Ph.D. - Publications

Affiliations: 
2015- Structural Biology Initiative City University of New York, New York, NY, United States 
Area:
Structural Biology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Xu X, Gagné D, Aramini JM, Gardner KH. Volume and Compressibility Differences Between Protein Conformations Revealed by High-Pressure NMR. Biophysical Journal. PMID 33524371 DOI: 10.1016/j.bpj.2020.12.034  0.683
2020 Narayanan C, Bernard DN, Letourneau M, Gagnon J, Gagné D, Bafna K, Calmettes C, Couture JF, Agarwal PK, Doucet N. Insights into structural and dynamical changes experienced by human RNase 6 upon ligand binding. Biochemistry. PMID 31909602 DOI: 10.1021/Acs.Biochem.9B00888  0.796
2019 Gobeil SMC, Ebert MCCJC, Park J, Gagné D, Doucet N, Berghuis AM, Pleiss J, Pelletier JN. The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Scientific Reports. 9: 6656. PMID 31040324 DOI: 10.1038/S41598-019-42866-8  0.738
2018 Gagné D, Narayanan C, Bafna K, Charest LA, Agarwal PK, Doucet N. Correction to: Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin. Biomolecular Nmr Assignments. PMID 30083869 DOI: 10.1007/s12104-018-9833-4  0.752
2018 Narayanan C, Bernard DN, Bafna K, Gagné D, Agarwal PK, Doucet N. Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily. Frontiers in Molecular Biosciences. 5: 54. PMID 29946547 DOI: 10.3389/Fmolb.2018.00054  0.785
2018 Narayanan C, Bernard DN, Bafna K, Gagné D, Chennubhotla CS, Doucet N, Agarwal PK. Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily. Structure (London, England : 1993). PMID 29478822 DOI: 10.1016/J.Str.2018.01.015  0.794
2017 Narayanan C, Gagné D, Reynolds KA, Doucet N. Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily. Scientific Reports. 7: 3207. PMID 28600532 DOI: 10.1038/S41598-017-03298-4  0.771
2017 Gagné D, Narayanan C, Bafna K, Charest LA, Agarwal PK, Doucet N. Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin. Biomolecular Nmr Assignments. PMID 28271277 DOI: 10.1007/S12104-017-9736-9  0.788
2017 Gagnon J, Sarvan S, Gagne D, Couture J, Doucet N. Human ribonuclease 6 crystal structure and conformational analysis Acta Crystallographica Section A. 73. DOI: 10.1107/S2053273317091732  0.621
2016 Gagné D, Narayanan C, Nguyen Thi N, Roux LD, Bernard DN, Brunzelle JS, Couture JF, Agarwal PK, Doucet N. Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans. Biochemistry. PMID 27387012 DOI: 10.1021/Acs.Biochem.6B00130  0.795
2016 Herrero C, Nguyen-Thi N, Hammerer F, Banse F, Gagné D, Doucet N, Mahy J, Ricoux R. Photoassisted Oxidation of Sulfides Catalyzed by Artificial Metalloenzymes Using Water as an Oxygen Source Catalysts. 6: 202. DOI: 10.3390/Catal6120202  0.561
2016 Gagnon J, Sarvan S, Gagné D, Couture J, Simonović M, Doucet N. Crystal structure and biophysical characterization of ligand-free and -bound RNases 4 and 6, members of the human RNase A superfamily Acta Crystallographica Section a Foundations and Advances. 72: s215-s215. DOI: 10.1107/S2053273316096753  0.642
2015 Gagné D, French RL, Narayanan C, Simonović M, Agarwal PK, Doucet N. Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure (London, England : 1993). 23: 2256-2266. PMID 26655472 DOI: 10.1016/J.Str.2015.10.011  0.8
2015 Vladoiu MC, Labrie M, Létourneau M, Egesborg P, Gagné D, Billard É, Grosset AA, Doucet N, Chatenet D, St-Pierre Y. Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin. Oncotarget. PMID 26543238 DOI: 10.18632/Oncotarget.5403  0.603
2015 Gobeil SM, Gagné D, Doucet N, Pelletier JN. (15)N, (13)C and (1)H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant. Biomolecular Nmr Assignments. PMID 26386961 DOI: 10.1007/S12104-015-9645-8  0.731
2015 Gagné D, Narayanan C, Doucet N. Network of long-range concerted chemical shift displacements upon ligand binding to human angiogenin. Protein Science : a Publication of the Protein Society. 24: 525-33. PMID 25450558 DOI: 10.1002/Pro.2613  0.793
2015 Gagné D, Doucet N. Sequence-specific backbone (1)H, (13)C, and (15)N resonance assignments of human ribonuclease 4. Biomolecular Nmr Assignments. 9: 181-5. PMID 25030111 DOI: 10.1007/S12104-014-9570-2  0.684
2015 Gobeil SMC, Gagne D, Doucet N, Pelletier JN. 15N, 13C and 1H backbone resonance assignments of TEM-1(M68L-M69T) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr26586  0.686
2015 St-Pierre Y, Grosset A, Labrie M, Gagné D, Vladoiu M, Gaboury L, Doucet N. Abstract P1-07-16: Galectin-7 increases resistance of breast cancer cells to drug-induced apoptosis and promotes tumor escape by killing T cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-16  0.577
2014 Grosset AA, Labrie M, Gagné D, Vladoiu MC, Gaboury L, Doucet N, St-Pierre Y. Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells. Bmc Cancer. 14: 801. PMID 25367122 DOI: 10.1186/1471-2407-14-801  0.574
2014 Gobeil SM, Clouthier CM, Park J, Gagné D, Berghuis AM, Doucet N, Pelletier JN. Maintenance of native-like protein dynamics may not be required for engineering functional proteins. Chemistry & Biology. 21: 1330-40. PMID 25200606 DOI: 10.1016/J.Chembiol.2014.07.016  0.757
2014 Grosset A, Gagné D, Labrie M, Vladoiu M, Gaboury L, Doucet N, St-Pierre Y. Abstract 1352: Cytoplasmic galectin-7 has an antiapoptotic function by decreasing p53 nuclear translocation in breast cancer cells Cancer Research. 74: 1352-1352. DOI: 10.1158/1538-7445.Am2014-1352  0.585
2014 Gagné D, Couture J, Simonović M, Doucet N. Structural and biophysical characterization of human RNase 6 Acta Crystallographica Section a Foundations and Advances. 70: C1643-C1643. DOI: 10.1107/S2053273314083569  0.687
1994 Martel C, Gagné D, Couet J, Labrie Y, Simard J, Labrie F. Rapid modulation of ovarian 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat Molecular and Cellular Endocrinology. 99: 63-71. PMID 8187962 DOI: 10.1016/0303-7207(94)90147-3  0.334
1994 Martel C, Meiner MH, Gagné D, Simarda J, Labrie F. Widespread tissue distribution of steroid sulfatase, 3β-hydroxysteroid dehydrogenase/Δ5-Δ4isomerase(3β-HSD), 17β-HSD5α-reductase and aromatase activities in the rhesus monkey Molecular and Cellular Endocrinology. 104: 103-111. PMID 7821701 DOI: 10.1016/0303-7207(94)90056-6  0.339
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