Eva Nogales - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, Berkeley, Berkeley, CA 
Website:
http://mcb.berkeley.edu/index.php?option=com_mcbfaculty&name=nogalese

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, ... ... Nogales E, et al. Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature. PMID 30944483 DOI: 10.1038/s41586-019-1084-8  0.84
2019 Greber BJ, Toso DB, Fang J, Nogales E. The complete structure of the human TFIIH core complex. Elife. 8. PMID 30860024 DOI: 10.7554/eLife.44771  0.72
2019 Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, ... ... Nogales E, et al. CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature. PMID 30718774 DOI: 10.1038/s41586-019-0908-x  0.84
2018 Jiang F, Liu JJ, Osuna BA, Xu M, Berry JD, Rauch BJ, Nogales E, Bondy-Denomy J, Doudna JA. Temperature-Responsive Competitive Inhibition of CRISPR-Cas9. Molecular Cell. PMID 30595438 DOI: 10.1016/j.molcel.2018.11.016  0.84
2018 Kasinath V, Poepsel S, Nogales E. Recent structural insights into PRC2 regulation and substrate binding. Biochemistry. PMID 30451485 DOI: 10.1021/acs.biochem.8b01064  0.48
2018 Patel AB, Louder RK, Greber BJ, Grünberg S, Luo J, Fang J, Liu Y, Ranish J, Hahn S, Nogales E. Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science (New York, N.Y.). PMID 30442764 DOI: 10.1126/science.aau8872  0.8
2018 Iwai M, Grob P, Iavarone AT, Nogales E, Niyogi KK. A unique supramolecular organization of photosystem I in the moss Physcomitrella patens. Nature Plants. 4: 904-909. PMID 30374090 DOI: 10.1038/s41477-018-0271-1  0.44
2018 Zhang R, LaFrance B, Nogales E. Separating the effects of nucleotide and EB binding on microtubule structure. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915050 DOI: 10.1073/pnas.1802637115  1
2018 Kellogg EH, Hejab NMA, Poepsel S, Downing KH, DiMaio F, Nogales E. Near-atomic model of microtubule-tau interactions. Science (New York, N.Y.). PMID 29748322 DOI: 10.1126/science.aat1780  1
2018 Nguyen THD, Tam J, Wu RA, Greber BJ, Toso D, Nogales E, Collins K. Cryo-EM structure of substrate-bound human telomerase holoenzyme. Nature. PMID 29695869 DOI: 10.1038/s41586-018-0062-x  0.4
2018 Poepsel S, Kasinath V, Nogales E. Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes. Nature Structural & Molecular Biology. PMID 29379173 DOI: 10.1038/s41594-018-0023-y  0.48
2018 Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E. Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science (New York, N.Y.). PMID 29348366 DOI: 10.1126/science.aar5700  0.48
2017 Howes SC, Geyer EA, LaFrance B, Zhang R, Kellogg EH, Westermann S, Rice LM, Nogales E. Structural and functional differences between porcine brain and budding yeast microtubules. Cell Cycle (Georgetown, Tex.). 1-22. PMID 29278985 DOI: 10.1080/15384101.2017.1415680  1
2017 Tenthorey JL, Haloupek N, López-Blanco JR, Grob P, Adamson E, Hartenian E, Lind NA, Bourgeois NM, Chacón P, Nogales E, Vance RE. The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science (New York, N.Y.). 358: 888-893. PMID 29146805 DOI: 10.1126/science.aao1140  0.72
2017 Zhang R, Roostalu J, Surrey T, Nogales E. Structural insight into TPX2-stimulated microtubule assembly. Elife. 6. PMID 29120325 DOI: 10.7554/eLife.30959  1
2017 Greber BJ, Nguyen THD, Fang J, Afonine PV, Adams PD, Nogales E. The cryo-electron microscopy structure of human transcription factor IIH. Nature. PMID 28902838 DOI: 10.1038/nature23903  0.72
2017 Wright AV, Liu JJ, Knott GJ, Doxzen KW, Nogales E, Doudna JA. Structures of the CRISPR genome integration complex. Science (New York, N.Y.). PMID 28729350 DOI: 10.1126/science.aao0679  0.84
2017 Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA. Disabling Cas9 by an anti-CRISPR DNA mimic. Science Advances. 3: e1701620. PMID 28706995 DOI: 10.1126/sciadv.1701620  0.84
2017 Howes SC, Geyer EA, LaFrance B, Zhang R, Kellogg EH, Westermann S, Rice LM, Nogales E. Structural differences between yeast and mammalian microtubules revealed by cryo-EM. The Journal of Cell Biology. PMID 28652389 DOI: 10.1083/jcb.201612195  1
2017 Nogales E, Kellogg EH. Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners. Current Opinion in Structural Biology. 46: 65-70. PMID 28628789 DOI: 10.1016/j.sbi.2017.06.003  0.68
2017 Nogales E, Patel AB, Louder RK. Towards a mechanistic understanding of core promoter recognition from cryo-EM studies of human TFIID. Current Opinion in Structural Biology. 47: 60-66. PMID 28624568 DOI: 10.1016/j.sbi.2017.05.015  0.8
2017 Nogales E, Louder RK, He Y. Structural Insights into the Eukaryotic Transcription Initiation Machinery. Annual Review of Biophysics. 46: 59-83. PMID 28532216 DOI: 10.1146/annurev-biophys-070816-033751  0.8
2017 Xu CS, Hayworth KJ, Lu Z, Grob P, Hassan AM, García-Cerdán JG, Niyogi KK, Nogales E, Weinberg RJ, Hess HF. Enhanced FIB-SEM systems for large-volume 3D imaging. Elife. 6. PMID 28500755 DOI: 10.7554/eLife.25916  0.44
2017 Kellogg EH, Hejab NM, Howes S, Northcote P, Miller JH, Fernando Díaz J, Downing KH, Nogales E. Insights into the distinct mechanisms of action of taxane and non-taxane microtubule stabilizers from cryo-EM structures. Journal of Molecular Biology. PMID 28104363 DOI: 10.1016/j.jmb.2017.01.001  1
2016 Nogales E, Fang J, Louder RK. Structural dynamics and DNA interaction of human TFIID. Transcription. 0. PMID 27935424 DOI: 10.1080/21541264.2016.1265701  0.8
2016 Booth EA, Sterling SM, Dovala D, Nogales E, Thorner J. Effects of Bni5 Binding on Septin Filament Organization. Journal of Molecular Biology. PMID 27806918 DOI: 10.1016/j.jmb.2016.10.024  0.44
2016 Nogales E, Louder RK, He Y. Cryo-EM in the study of challenging systems: the human transcription pre-initiation complex. Current Opinion in Structural Biology. 40: 120-127. PMID 27689812 DOI: 10.1016/j.sbi.2016.09.009  1
2016 Hochstrasser ML, Taylor DW, Kornfeld JE, Nogales E, Doudna JA. DNA Targeting by a Minimal CRISPR RNA-Guided Cascade. Molecular Cell. 63: 840-51. PMID 27588603 DOI: 10.1016/j.molcel.2016.07.027  0.84
2016 Kellogg EH, Howes S, Ti SC, Ramírez-Aportela E, Kapoor TM, Chacón P, Nogales E. Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proceedings of the National Academy of Sciences of the United States of America. PMID 27493215 DOI: 10.1073/pnas.1609903113  0.72
2016 He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E. Near-atomic resolution visualization of human transcription promoter opening. Nature. 533: 359-65. PMID 27193682 DOI: 10.1038/nature17970  0.8
2016 Finnigan GC, Sterling SM, Duvalyan A, Liao EN, Sargsyan A, Garcia G, Nogales E, Thorner J. Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae. Molecular Biology of the Cell. PMID 27193302 DOI: 10.1091/mbc.E16-03-0177  0.44
2016 Borisy G, Heald R, Howard J, Janke C, Musacchio A, Nogales E. Microtubules: 50 years on from the discovery of tubulin. Nature Reviews. Molecular Cell Biology. 17: 322-8. PMID 27103327 DOI: 10.1038/nrm.2016.45  1
2016 Louder RK, He Y, López-Blanco JR, Fang J, Chacón P, Nogales E. Corrigendum: Structure of promoter-bound TFIID and model of human pre-initiation complex assembly. Nature. PMID 27096372 DOI: 10.1038/nature17984  0.8
2016 Ti SC, Pamula MC, Howes SC, Duellberg C, Cade NI, Kleiner RE, Forth S, Surrey T, Nogales E, Kapoor TM. Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends. Developmental Cell. 37: 72-84. PMID 27046833 DOI: 10.1016/j.devcel.2016.03.003  1
2016 Louder RK, He Y, López-Blanco JR, Fang J, Chacón P, Nogales E. Structure of promoter-bound TFIID and model of human pre-initiation complex assembly. Nature. PMID 27007846 DOI: 10.1038/nature17394  1
2016 Garcia G, Finnigan GC, Heasley LR, Sterling SM, Aggarwal A, Pearson CG, Nogales E, McMurray MA, Thorner J. Assembly, molecular organization, and membrane-binding properties of development-specific septins. The Journal of Cell Biology. 212: 515-29. PMID 26929450 DOI: 10.1083/jcb.201511029  1
2016 Jiang F, Taylor DW, Chen JS, Kornfeld JE, Zhou K, Thompson AJ, Nogales E, Doudna JA. Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage. Science (New York, N.Y.). 351: 867-71. PMID 26841432 DOI: 10.1126/science.aad8282  1
2016 Nogales E, Zhang R. Visualizing microtubule structural transitions and interactions with associated proteins. Current Opinion in Structural Biology. 37: 90-96. PMID 26803284 DOI: 10.1016/j.sbi.2015.12.009  1
2016 Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, ... ... Nogales E, et al. Mutations in TUBB8 and Human Oocyte Meiotic Arrest. The New England Journal of Medicine. 374: 223-232. PMID 26789871 DOI: 10.1056/NEJMoa1510791  1
2016 Bertin A, Nogales E. Characterization of Septin Ultrastructure in Budding Yeast Using Electron Tomography. Methods in Molecular Biology (Clifton, N.J.). 1369: 113-23. PMID 26519309 DOI: 10.1007/978-1-4939-3145-3_9  1
2015 Zhang ET, He Y, Grob P, Fong YW, Nogales E, Tjian R. Architecture of the human XPC DNA repair and stem cell coactivator complex. Proceedings of the National Academy of Sciences of the United States of America. 112: 14817-22. PMID 26627236 DOI: 10.1073/pnas.1520104112  1
2015 Diao J, Grob P, Cipriano DJ, Kyoung M, Zhang Y, Shah S, Nguyen A, Padolina M, Srivastava A, Vrljic M, Shah A, Nogales E, Chu S, Brunger AT. Correction: Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife. 4. PMID 26486862 DOI: 10.7554/eLife.12289  0.44
2015 Ciferri C, Lander GC, Nogales E. Protein domain mapping by internal labeling and single particle electron microscopy. Journal of Structural Biology. 192: 159-62. PMID 26431894 DOI: 10.1016/j.jsb.2015.09.016  0.68
2015 Zhang R, Nogales E. A new protocol to accurately determine microtubule lattice seam location. Journal of Structural Biology. 192: 245-54. PMID 26424086 DOI: 10.1016/j.jsb.2015.09.015  1
2015 Nogales E. An electron microscopy journey in the study of microtubule structure and dynamics. Protein Science : a Publication of the Protein Society. PMID 26401895 DOI: 10.1002/pro.2808  1
2015 Zhang R, Alushin GM, Brown A, Nogales E. Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell. PMID 26234155 DOI: 10.1016/j.cell.2015.07.012  1
2015 Nogales E, Scheres SH. Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity. Molecular Cell. 58: 677-689. PMID 26000851 DOI: 10.1016/j.molcel.2015.02.019  1
2015 Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA. Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning. Science (New York, N.Y.). 348: 581-5. PMID 25837515 DOI: 10.1126/science.aaa4535  0.84
2015 Nogales E. The development of cryo-EM into a mainstream structural biology technique Nature Methods. 13: 24-27. DOI: 10.1038/nmeth.3694  1
2014 Baskaran S, Carlson LA, Stjepanovic G, Young LN, Kim do J, Grob P, Stanley RE, Nogales E, Hurley JH. Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex. Elife. 3. PMID 25490155 DOI: 10.7554/eLife.05115  1
2014 Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, ... ... Nogales E, et al. RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell. 56: 518-30. PMID 25457165 DOI: 10.1016/j.molcel.2014.10.005  0.84
2014 Nakamura M, Chen L, Howes SC, Schindler TD, Nogales E, Bryant Z. Remote control of myosin and kinesin motors using light-activated gearshifting. Nature Nanotechnology. 9: 693-7. PMID 25086603 DOI: 10.1038/nnano.2014.147  1
2014 Onoa B, Schneider AR, Brooks MD, Grob P, Nogales E, Geissler PL, Niyogi KK, Bustamante C. Atomic force microscopy of photosystem II and its unit cell clustering quantitatively delineate the mesoscale variability in Arabidopsis thylakoids. Plos One. 9: e101470. PMID 25007326 DOI: 10.1371/journal.pone.0101470  1
2014 Alushin GM, Lander GC, Kellogg EH, Zhang R, Baker D, Nogales E. High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis. Cell. 157: 1117-29. PMID 24855948 DOI: 10.1016/j.cell.2014.03.053  1
2014 Clausen CH, Brooks MD, Li TD, Grob P, Kemalyan G, Nogales E, Niyogi KK, Fletcher DA. Dynamic mechanical responses of Arabidopsis thylakoid membranes during PSII-specific illumination. Biophysical Journal. 106: 1864-70. PMID 24806918 DOI: 10.1016/j.bpj.2014.03.016  1
2014 Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Sternberg SH, Nogales E, Doudna JA. CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference. Proceedings of the National Academy of Sciences of the United States of America. 111: 6618-23. PMID 24748111 DOI: 10.1073/pnas.1405079111  0.84
2014 Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science (New York, N.Y.). 343: 1247997. PMID 24505130 DOI: 10.1126/science.1247997  1
2014 Howes SC, Alushin GM, Shida T, Nachury MV, Nogales E. Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure. Molecular Biology of the Cell. 25: 257-66. PMID 24227885 DOI: 10.1091/mbc.E13-07-0387  1
2013 Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM. A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation. Elife. 2: e00882. PMID 24137536 DOI: 10.7554/eLife.00882  1
2013 Musinipally V, Howes S, Alushin GM, Nogales E. The microtubule binding properties of CENP-E's C-terminus and CENP-F. Journal of Molecular Biology. 425: 4427-41. PMID 23892111 DOI: 10.1016/j.jmb.2013.07.027  1
2013 Cianfrocco MA, Nogales E. Regulatory interplay between TFIID's conformational transitions and its modular interaction with core promoter DNA. Transcription. 4: 120-6. PMID 23863784 DOI: 10.4161/trns.25291  1
2013 de Val N, McMurray MA, Lam LH, Hsiung CC, Bertin A, Nogales E, Thorner J. Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins. Proteins. 81: 1964-79. PMID 23775754 DOI: 10.1002/prot.24345  1
2013 Sun C, Querol-Audí J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH. Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation. Nucleic Acids Research. 41: 7512-21. PMID 23766293 DOI: 10.1093/nar/gkt510  0.84
2013 Kassube SA, Jinek M, Fang J, Tsutakawa S, Nogales E. Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5. Nature Structural & Molecular Biology. 20: 892-9. PMID 23748380 DOI: 10.1038/nsmb.2596  1
2013 Grob P, Bean D, Typke D, Li X, Nogales E, Glaeser RM. Ranking TEM cameras by their response to electron shot noise. Ultramicroscopy. 133: 1-7. PMID 23747527 DOI: 10.1016/j.ultramic.2013.01.003  1
2013 Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW. Substrate-specific structural rearrangements of human Dicer. Nature Structural & Molecular Biology. 20: 662-70. PMID 23624860 DOI: 10.1038/nsmb.2564  1
2013 Querol-Audi J, Sun C, Vogan JM, Smith MD, Gu Y, Cate JH, Nogales E. Architecture of human translation initiation factor 3. Structure (London, England : 1993). 21: 920-8. PMID 23623729 DOI: 10.1016/j.str.2013.04.002  1
2013 Lander GC, Martin A, Nogales E. The proteasome under the microscope: the regulatory particle in focus. Current Opinion in Structural Biology. 23: 243-51. PMID 23498601 DOI: 10.1016/j.sbi.2013.02.004  1
2013 Galbraith CG, Keller PJ, Nogales E. New technologies in imaging. Molecular Biology of the Cell. 24: 669. PMID 23486393 DOI: 10.1091/mbc.E12-12-0867  1
2013 He Y, Fang J, Taatjes DJ, Nogales E. Structural visualization of key steps in human transcription initiation. Nature. 495: 481-6. PMID 23446344 DOI: 10.1038/nature11991  1
2013 Cianfrocco MA, Kassavetis GA, Grob P, Fang J, Juven-Gershon T, Kadonaga JT, Nogales E. Human TFIID binds to core promoter DNA in a reorganized structural state. Cell. 152: 120-31. PMID 23332750 DOI: 10.1016/j.cell.2012.12.005  1
2013 Lampert F, Mieck C, Alushin GM, Nogales E, Westermann S. Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes. The Journal of Cell Biology. 200: 21-30. PMID 23277429 DOI: 10.1083/jcb.201210091  1
2013 Kassube SA, Fang J, Grob P, Yakovchuk P, Goodrich JA, Nogales E. Structural insights into transcriptional repression by noncoding RNAs that bind to human Pol II. Journal of Molecular Biology. 425: 3639-48. PMID 22954660 DOI: 10.1016/j.jmb.2012.08.024  1
2013 Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM. A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation Elife. 2013. DOI: 10.7554/eLife.00882.001  1
2012 Bertin A, Nogales E. Septin filament organization in Saccharomyces cerevisiae. Communicative & Integrative Biology. 5: 503-5. PMID 23739625 DOI: 10.4161/cib.21125  1
2012 Diao J, Grob P, Cipriano DJ, Kyoung M, Zhang Y, Shah S, Nguyen A, Padolina M, Srivastava A, Vrljic M, Shah A, Nogales E, Chu S, Brunger AT. Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife. 1: e00109. PMID 23240085 DOI: 10.7554/eLife.00109  1
2012 Ciferri C, Lander GC, Maiolica A, Herzog F, Aebersold R, Nogales E. Molecular architecture of human polycomb repressive complex 2. Elife. 1: e00005. PMID 23110252 DOI: 10.7554/eLife.00005  1
2012 Alushin GM, Musinipally V, Matson D, Tooley J, Stukenberg PT, Nogales E. Multimodal microtubule binding by the Ndc80 kinetochore complex. Nature Structural & Molecular Biology. 19: 1161-7. PMID 23085714 DOI: 10.1038/nsmb.2411  1
2012 Lander GC, Saibil HR, Nogales E. Go hybrid: EM, crystallography, and beyond. Current Opinion in Structural Biology. 22: 627-35. PMID 22835744 DOI: 10.1016/j.sbi.2012.07.006  1
2012 Wu Z, Nogales E, Xing J. Comparative studies of microtubule mechanics with two competing models suggest functional roles of alternative tubulin lateral interactions. Biophysical Journal. 102: 2687-96. PMID 22735518 DOI: 10.1016/j.bpj.2012.05.003  1
2012 Querol-Audí J, Yan C, Xu X, Tsutakawa SE, Tsai MS, Tainer JA, Cooper PK, Nogales E, Ivanov I. Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability. Proceedings of the National Academy of Sciences of the United States of America. 109: 8528-33. PMID 22586102 DOI: 10.1073/pnas.1121116109  1
2012 Hudak JE, Barfield RM, de Hart GW, Grob P, Nogales E, Bertozzi CR, Rabuka D. Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angewandte Chemie (International Ed. in English). 51: 4161-5. PMID 22407566 DOI: 10.1002/anie.201108130  1
2012 Patel K, Nogales E, Heald R. Multiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts. Cytoskeleton (Hoboken, N.J.). 69: 155-65. PMID 22278908 DOI: 10.1002/cm.21005  1
2012 Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Complete subunit architecture of the proteasome regulatory particle. Nature. 482: 186-91. PMID 22237024 DOI: 10.1038/nature10774  1
2012 Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, García G, Peters P, Thorner J, Nogales E. Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Molecular Biology of the Cell. 23: 423-32. PMID 22160597 DOI: 10.1091/mbc.E11-10-0850  1
2012 Grob P, Zhang TT, Hannah R, Yang H, Hefferin ML, Tomkinson AE, Nogales E. Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV. Dna Repair. 11: 74-81. PMID 22088982 DOI: 10.1016/j.dnarep.2011.10.023  1
2012 Nogales E, Alushin G. Tubulin and microtubule structure: Mechanistic insights into dynamic instability and its biological relevance Comprehensive Biophysics. 4: 72-92. DOI: 10.1016/B978-0-12-374920-8.00407-0  1
2011 Garcia G, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E. Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. The Journal of Cell Biology. 195: 993-1004. PMID 22144691 DOI: 10.1083/jcb.201107123  1
2011 Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH. Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3). Proceedings of the National Academy of Sciences of the United States of America. 108: 20473-8. PMID 22135459 DOI: 10.1073/pnas.1116821108  0.84
2011 Ramey VH, Wong A, Fang J, Howes S, Barnes G, Nogales E. Subunit organization in the Dam1 kinetochore complex and its ring around microtubules. Molecular Biology of the Cell. 22: 4335-42. PMID 21965284 DOI: 10.1091/mbc.E11-07-0659  1
2011 Wiedenheft B, Lander GC, Zhou K, Jore MM, Brouns SJ, van der Oost J, Doudna JA, Nogales E. Structures of the RNA-guided surveillance complex from a bacterial immune system. Nature. 477: 486-9. PMID 21938068 DOI: 10.1038/nature10402  0.84
2011 Alushin G, Nogales E. Visualizing kinetochore architecture. Current Opinion in Structural Biology. 21: 661-9. PMID 21862320 DOI: 10.1016/j.sbi.2011.07.009  1
2011 Núñez-Ramírez R, Klinge S, Sauguet L, Melero R, Recuero-Checa MA, Kilkenny M, Perera RL, García-Alvarez B, Hall RJ, Nogales E, Pellegrini L, Llorca O. Flexible tethering of primase and DNA Pol α in the eukaryotic primosome. Nucleic Acids Research. 39: 8187-99. PMID 21715379 DOI: 10.1093/nar/gkr534  1
2011 Kyoung M, Srivastava A, Zhang Y, Diao J, Vrljic M, Grob P, Nogales E, Chu S, Brunger AT. In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. 108: E304-13. PMID 21705659 DOI: 10.1073/pnas.1107900108  1
2011 McMurray MA, Bertin A, Garcia G, Lam L, Nogales E, Thorner J. Septin filament formation is essential in budding yeast. Developmental Cell. 20: 540-9. PMID 21497764 DOI: 10.1016/j.devcel.2011.02.004  1
2011 Bernecky C, Grob P, Ebmeier CC, Nogales E, Taatjes DJ. Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. Plos Biology. 9: e1000603. PMID 21468301 DOI: 10.1371/journal.pbio.1000603  1
2011 Hall RJ, Nogales E, Glaeser RM. Accurate modeling of single-particle cryo-EM images quantitates the benefits expected from using Zernike phase contrast. Journal of Structural Biology. 174: 468-75. PMID 21463690 DOI: 10.1016/j.jsb.2011.03.020  1
2011 Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM. The structural basis for MCM2-7 helicase activation by GINS and Cdc45. Nature Structural & Molecular Biology. 18: 471-7. PMID 21378962 DOI: 10.1038/nsmb.2004  1
2011 Screpanti E, De Antoni A, Alushin GM, Petrovic A, Melis T, Nogales E, Musacchio A. Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. Current Biology : Cb. 21: 391-8. PMID 21353556 DOI: 10.1016/j.cub.2010.12.039  1
2011 Ramey VH, Wang HW, Nakajima Y, Wong A, Liu J, Drubin D, Barnes G, Nogales E. The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule. Molecular Biology of the Cell. 22: 457-66. PMID 21169562 DOI: 10.1091/mbc.E10-10-0841  1
2011 Hornung P, Maier M, Alushin GM, Lander GC, Nogales E, Westermann S. Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. Journal of Molecular Biology. 405: 548-59. PMID 21075115 DOI: 10.1016/j.jmb.2010.11.012  1
2010 Nogales E. My dream of a fantastic voyage to see the inner workings of a cell. Molecular Biology of the Cell. 21: 3815. PMID 21079026 DOI: 10.1091/mbc.E10-05-0385  1
2010 Nogales E. When cytoskeletal worlds collide. Proceedings of the National Academy of Sciences of the United States of America. 107: 19609-10. PMID 21059902 DOI: 10.1073/pnas.1014665107  1
2010 Bertin A, McMurray MA, Thai L, Garcia G, Votin V, Grob P, Allyn T, Thorner J, Nogales E. Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization. Journal of Molecular Biology. 404: 711-31. PMID 20951708 DOI: 10.1016/j.jmb.2010.10.002  1
2010 Alushin GM, Ramey VH, Pasqualato S, Ball DA, Grigorieff N, Musacchio A, Nogales E. The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature. 467: 805-10. PMID 20944740 DOI: 10.1038/nature09423  1
2010 Downing KH, Nogales E. Cryoelectron microscopy applications in the study of tubulin structure, microtubule architecture, dynamics and assemblies, and interaction of microtubules with motors. Methods in Enzymology. 483: 121-42. PMID 20888472 DOI: 10.1016/S0076-6879(10)83006-X  1
2010 Tang L, Nogales E, Ciferri C. Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription. Progress in Biophysics and Molecular Biology. 102: 122-8. PMID 20493208 DOI: 10.1016/j.pbiomolbio.2010.05.001  1
2010 Nogales E, Ramey VH, Wang HW. Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions. Methods in Cell Biology. 95: 129-56. PMID 20466133 DOI: 10.1016/S0091-679X(10)95008-5  1
2010 Shatsky M, Hall RJ, Nogales E, Malik J, Brenner SE. Automated multi-model reconstruction from single-particle electron microscopy data. Journal of Structural Biology. 170: 98-108. PMID 20085819 DOI: 10.1016/j.jsb.2010.01.007  1
2009 Nogales E, Ramey VH. Structure-function insights into the yeast Dam1 kinetochore complex. Journal of Cell Science. 122: 3831-6. PMID 19889968 DOI: 10.1242/jcs.004689  1
2009 Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E. Structural insights into RNA processing by the human RISC-loading complex. Nature Structural & Molecular Biology. 16: 1148-53. PMID 19820710 DOI: 10.1038/nsmb.1673  1
2009 Wu Z, Wang HW, Mu W, Ouyang Z, Nogales E, Xing J. Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly. Plos One. 4: e7291. PMID 19806219 DOI: 10.1371/journal.pone.0007291  1
2009 Liu WL, Coleman RA, Ma E, Grob P, Yang JL, Zhang Y, Dailey G, Nogales E, Tjian R. Structures of three distinct activator-TFIID complexes. Genes & Development. 23: 1510-21. PMID 19571180 DOI: 10.1101/gad.1790709  1
2009 Ramey VH, Wang HW, Nogales E. Ab initio reconstruction of helical samples with heterogeneity, disorder and coexisting symmetries. Journal of Structural Biology. 167: 97-105. PMID 19447181 DOI: 10.1016/j.jsb.2009.05.002  1
2009 Scheres SH, Valle M, Grob P, Nogales E, Carazo JM. Maximum likelihood refinement of electron microscopy data with normalization errors. Journal of Structural Biology. 166: 234-40. PMID 19236920 DOI: 10.1016/j.jsb.2009.02.007  1
2009 Hall RJ, Glaeser RM, Nogales E. Computational modeling of the benefits expected for zernike phase contrast in cryo-EM Microscopy and Microanalysis. 15: 94-95. DOI: 10.1017/S1431927609092393  1
2009 Khodiyar VK, Maltais LJ, Ruef BJ, Sneddon KMB, Smith JR, Shimoyama M, Cabral F, Dumontet C, Dutcher SK, Harvey RJ, Lafanechère L, Murray JM, Nogales E, Piquemal D, Stanchi F, et al. Corrigendum to "A revised nomenclature for the human and rodent α-tubulin gene family" [Genomics 90 (2007) 285-289] (DOI:10.1016/j.ygeno.2007.04.008) Genomics. 93: 397. DOI: 10.1016/j.ygeno.2008.12.002  1
2008 Clarey MG, Botchan M, Nogales E. Single particle EM studies of the Drosophila melanogaster origin recognition complex and evidence for DNA wrapping. Journal of Structural Biology. 164: 241-9. PMID 18824234 DOI: 10.1016/j.jsb.2008.08.006  1
2008 Wang HW, Long S, Ciferri C, Westermann S, Drubin D, Barnes G, Nogales E. Architecture and flexibility of the yeast Ndc80 kinetochore complex. Journal of Molecular Biology. 383: 894-903. PMID 18793650 DOI: 10.1016/j.jmb.2008.08.077  1
2008 Bertin A, McMurray MA, Grob P, Park SS, Garcia G, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E. Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proceedings of the National Academy of Sciences of the United States of America. 105: 8274-9. PMID 18550837 DOI: 10.1073/pnas.0803330105  1
2008 Liu WL, Coleman RA, Grob P, King DS, Florens L, Washburn MP, Geles KG, Yang JL, Ramey V, Nogales E, Tjian R. Structural changes in TAF4b-TFIID correlate with promoter selectivity. Molecular Cell. 29: 81-91. PMID 18206971 DOI: 10.1016/j.molcel.2007.11.003  1
2008 Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A. Single particle reconstruction of yeast RNA degradation machine, exosome, using electron microscopy Microscopy and Microanalysis. 14: 162-163. DOI: 10.1017/S1431927608089769  1
2007 Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A. Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing. Proceedings of the National Academy of Sciences of the United States of America. 104: 16844-9. PMID 17942686 DOI: 10.1073/pnas.0705526104  1
2007 Hall RJ, Siridechadilok B, Nogales E. Cross-correlation of common lines: a novel approach for single-particle reconstruction of a structure containing a flexible domain. Journal of Structural Biology. 159: 474-82. PMID 17646111 DOI: 10.1016/j.jsb.2007.05.007  1
2007 Wang HW, Ramey VH, Westermann S, Leschziner AE, Welburn JP, Nakajima Y, Drubin DG, Barnes G, Nogales E. Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms. Nature Structural & Molecular Biology. 14: 721-6. PMID 17643123 DOI: 10.1038/nsmb1274  1
2007 Khodiyar VK, Maltais LJ, Ruef BJ, Sneddon KM, Smith JR, Shimoyama M, Cabral F, Dumontet C, Dutcher SK, Harvey RJ, Lafanechère L, Murray JM, Nogales E, Piquemal D, Stanchi F, et al. A revised nomenclature for the human and rodent alpha-tubulin gene family. Genomics. 90: 285-9. PMID 17543498 DOI: 10.1016/j.ygeno.2007.04.008  1
2007 Chen B, Doucleff M, Wemmer DE, De Carlo S, Huang HH, Nogales E, Hoover TR, Kondrashkina E, Guo L, Nixon BT. ATP ground- and transition states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, sigma54. Structure (London, England : 1993). 15: 429-40. PMID 17437715 DOI: 10.1016/j.str.2007.02.007  1
2007 Garczarek F, Dong M, Typke D, Witkowska HE, Hazen TC, Nogales E, Biggin MD, Glaeser RM. Octomeric pyruvate-ferredoxin oxidoreductase from Desulfovibrio vulgaris. Journal of Structural Biology. 159: 9-18. PMID 17400475 DOI: 10.1016/j.jsb.2007.01.020  1
2007 Galburt EA, Grill SW, Wiedmann A, Lubkowska L, Choy J, Nogales E, Kashlev M, Bustamante C. Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. Nature. 446: 820-3. PMID 17361130 DOI: 10.1038/nature05701  1
2007 Leschziner AE, Saha A, Wittmeyer J, Zhang Y, Bustamante C, Cairns BR, Nogales E. Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method. Proceedings of the National Academy of Sciences of the United States of America. 104: 4913-8. PMID 17360331 DOI: 10.1073/pnas.0700706104  1
2007 Leschziner AE, Nogales E. Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions. Annual Review of Biophysics and Biomolecular Structure. 36: 43-62. PMID 17201674 DOI: 10.1146/annurev.biophys.36.040306.132742  1
2007 Nogales E, Sundquist WI. Macromolecular assemblages: focusing in on complexity Current Opinion in Structural Biology. 17: 205-208. DOI: 10.1016/j.sbi.2007.03.017  1
2006 Kostek SA, Grob P, De Carlo S, Lipscomb JS, Garczarek F, Nogales E. Molecular architecture and conformational flexibility of human RNA polymerase II. Structure (London, England : 1993). 14: 1691-700. PMID 17098194 DOI: 10.1016/j.str.2006.09.011  1
2006 Clarey MG, Erzberger JP, Grob P, Leschziner AE, Berger JM, Nogales E, Botchan M. Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex. Nature Structural & Molecular Biology. 13: 684-90. PMID 16829958 DOI: 10.1038/nsmb1121  1
2006 De Carlo S, Chen B, Hoover TR, Kondrashkina E, Nogales E, Nixon BT. The structural basis for regulated assembly and function of the transcriptional activator NtrC. Genes & Development. 20: 1485-95. PMID 16751184 DOI: 10.1101/gad.1418306  1
2006 Nogales E, Wang HW. Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives. Current Opinion in Structural Biology. 16: 221-9. PMID 16549346 DOI: 10.1016/j.sbi.2006.03.005  1
2006 Grob P, Cruse MJ, Inouye C, Peris M, Penczek PA, Tjian R, Nogales E. Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues. Structure (London, England : 1993). 14: 511-20. PMID 16531235 DOI: 10.1016/j.str.2005.11.020  1
2006 Nogales E, Wang HW. Structural intermediates in microtubule assembly and disassembly: how and why? Current Opinion in Cell Biology. 18: 179-84. PMID 16495041 DOI: 10.1016/j.ceb.2006.02.009  1
2006 Leschziner AE, Nogales E. The orthogonal tilt reconstruction method: an approach to generating single-class volumes with no missing cone for ab initio reconstruction of asymmetric particles. Journal of Structural Biology. 153: 284-99. PMID 16431136 DOI: 10.1016/j.jsb.2005.10.012  1
2006 Westermann S, Wang HW, Avila-Sakar A, Drubin DG, Nogales E, Barnes G. The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature. 440: 565-9. PMID 16415853 DOI: 10.1038/nature04409  1
2005 Siridechadilok B, Fraser CS, Hall RJ, Doudna JA, Nogales E. Structural roles for human translation factor eIF3 in initiation of protein synthesis. Science (New York, N.Y.). 310: 1513-5. PMID 16322461 DOI: 10.1126/science.1118977  0.84
2005 Sarker AH, Tsutakawa SE, Kostek S, Ng C, Shin DS, Peris M, Campeau E, Tainer JA, Nogales E, Cooper PK. Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome. Molecular Cell. 20: 187-98. PMID 16246722 DOI: 10.1016/j.molcel.2005.09.022  1
2005 Wang HW, Long S, Finley KR, Nogales E. Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine. Cell Cycle (Georgetown, Tex.). 4: 1157-60. PMID 16123589  1
2005 Wang HW, Nogales E. Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly. Nature. 435: 911-5. PMID 15959508 DOI: 10.1038/nature03606  1
2005 Leschziner AE, Lemon B, Tjian R, Nogales E. Structural studies of the human PBAF chromatin-remodeling complex. Structure (London, England : 1993). 13: 267-75. PMID 15698570 DOI: 10.1016/j.str.2004.12.008  1
2005 Westermann S, Avila-Sakar A, Wang HW, Niederstrasser H, Wong J, Drubin DG, Nogales E, Barnes G. Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Molecular Cell. 17: 277-90. PMID 15664196 DOI: 10.1016/j.molcel.2004.12.019  1
2005 Wang HW, Nogales E. An iterative Fourier-Bessel algorithm for reconstruction of helical structures with severe Bessel overlap. Journal of Structural Biology. 149: 65-78. PMID 15629658 DOI: 10.1016/j.jsb.2004.08.006  1
2004 Poruchynsky MS, Kim JH, Nogales E, Annable T, Loganzo F, Greenberger LM, Sackett DL, Fojo T. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability. Biochemistry. 43: 13944-54. PMID 15518543 DOI: 10.1021/bi049300+  1
2003 Nogales E, Wang HW, Niederstrasser H. Tubulin rings: which way do they curve? Current Opinion in Structural Biology. 13: 256-61. PMID 12727521 DOI: 10.1016/S0959-440X(03)00029-0  1
2002 Li H, DeRosier DJ, Nicholson WV, Nogales E, Downing KH. Microtubule structure at 8 A resolution. Structure (London, England : 1993). 10: 1317-28. PMID 12377118 DOI: 10.1016/S0969-2126(02)00827-4  1
2002 Näär AM, Taatjes DJ, Zhai W, Nogales E, Tjian R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes & Development. 16: 1339-44. PMID 12050112 DOI: 10.1101/gad.987602  1
2002 Niederstrasser H, Salehi-Had H, Gan EC, Walczak C, Nogales E. XKCM1 acts on a single protofilament and requires the C terminus of tubulin. Journal of Molecular Biology. 316: 817-28. PMID 11866534 DOI: 10.1006/jmbi.2001.5360  1
2002 Taatjes DJ, Näär AM, Andel F, Nogales E, Tjian R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science (New York, N.Y.). 295: 1058-62. PMID 11834832 DOI: 10.1126/science.1065249  1
2002 Heald R, Nogales E. Microtubule dynamics. Journal of Cell Science. 115: 3-4. PMID 11801717  1
2001 Avila-Sakar AJ, Misaghi S, Wilson-Kubalek EM, Downing KH, Zgurskaya H, Nikaido H, Nogales E. Lipid-layer crystallization and preliminary three-dimensional structural analysis of AcrA, the periplasmic component of a bacterial multidrug efflux pump Journal of Structural Biology. 136: 81-88. PMID 11858709 DOI: 10.1006/jsbi.2001.4418  1
2001 Löwe J, Li H, Downing KH, Nogales E. Refined structure of alpha beta-tubulin at 3.5 A resolution. Journal of Molecular Biology. 313: 1045-57. PMID 11700061 DOI: 10.1006/jmbi.2001.5077  1
2001 Jung MK, Prigozhina N, Oakley CE, Nogales E, Oakley BR. Alanine-scanning mutagenesis of Aspergillus gamma-tubulin yields diverse and novel phenotypes. Molecular Biology of the Cell. 12: 2119-36. PMID 11452008  1
2001 Nogales E. Structural insight into microtubule function. Annual Review of Biophysics and Biomolecular Structure. 30: 397-420. PMID 11441808 DOI: 10.1146/annurev.biophys.30.1.397  1
2001 Snyder JP, Nettles JH, Cornett B, Downing KH, Nogales E. The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density. Proceedings of the National Academy of Sciences of the United States of America. 98: 5312-6. PMID 11309480 DOI: 10.1073/pnas.051309398  1
2001 Nogales E, Grigorieff N. Molecular Machines: putting the pieces together. The Journal of Cell Biology. 152: F1-10. PMID 11149934  1
2001 Inclán YF, Nogales E. Structural models for the self-assembly and microtubule interactions of gamma-, delta- and epsilon-tubulin. Journal of Cell Science. 114: 413-22. PMID 11148142  1
2000 Nogales E. Recent structural insights into transcription preinitiation complexes. Journal of Cell Science. 113: 4391-7. PMID 11082032  1
2000 Nogales E. Structural insights into microtubule function. Annual Review of Biochemistry. 69: 277-302. PMID 10966460 DOI: 10.1146/annurev.biochem.69.1.277  1
2000 Detrich HW, Parker SK, Williams RC, Nogales E, Downing KH. Cold adaptation of microtubule assembly and dynamics. Structural interpretation of primary sequence changes present in the alpha- and beta-tubulins of Antarctic fishes. The Journal of Biological Chemistry. 275: 37038-47. PMID 10956651 DOI: 10.1074/jbc.M005699200  1
2000 Richards KL, Anders KR, Nogales E, Schwartz K, Downing KH, Botstein D. Structure-function relationships in yeast tubulins. Molecular Biology of the Cell. 11: 1887-903. PMID 10793159  1
2000 Paluh JL, Nogales E, Oakley BR, McDonald K, Pidoux AL, Cande WZ. A mutation in gamma-tubulin alters microtubule dynamics and organization and is synthetically lethal with the kinesin-like protein pkl1p. Molecular Biology of the Cell. 11: 1225-39. PMID 10749926  1
2000 Giannakakou P, Gussio R, Nogales E, Downing KH, Zaharevitz D, Bollbuck B, Poy G, Sackett D, Nicolaou KC, Fojo T. A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 2904-9. PMID 10688884 DOI: 10.1073/pnas.040546297  1
1999 Downing KH, Nogales E. Crystallographic structure of tubulin: implications for dynamics and drug binding. Cell Structure and Function. 24: 269-75. PMID 15216882 DOI: 10.1247/csf.24.269  1
1999 Han Y, Sablin EP, Nogales E, Fletterick RJ, Downing KH. Visualizing a new binding site of ncd-motor domain on tubulin. Journal of Structural Biology. 128: 26-33. PMID 10600555 DOI: 10.1006/jsbi.1999.4162  1
1999 Nogales E, Chiu W. Editorial Journal of Structural Biology. 128: 1-2. PMID 10600551 DOI: 10.1006/jsbi.1999.4190  1
1999 Nicholson WV, Lee M, Downing KH, Nogales E. Cryo-electron microscopy of GDP-tubulin rings. Cell Biochemistry and Biophysics. 31: 175-83. PMID 10593258 DOI: 10.1007/BF02738171  1
1999 Andel F, Ladurner AG, Inouye C, Tjian R, Nogales E. Three-dimensional structure of the human TFIID-IIA-IIB complex. Science (New York, N.Y.). 286: 2153-6. PMID 10591646 DOI: 10.1126/science.286.5447.2153  1
1999 Nogales E, Whittaker M, Milligan RA, Downing KH. High-resolution model of the microtubule. Cell. 96: 79-88. PMID 9989499 DOI: 10.1016/S0092-8674(00)80961-7  1
1999 Feierbach B, Nogales E, Downing KH, Stearns T. Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. The Journal of Cell Biology. 144: 113-24. PMID 9885248 DOI: 10.1083/jcb.144.1.113  1
1998 Downing KH, Nogales E. Tubulin structure: insights into microtubule properties and functions. Current Opinion in Structural Biology. 8: 785-91. PMID 9914260 DOI: 10.1016/S0959-440X(98)80099-7  1
1998 Downing KH, Nogales E. New insights into microtubule structure and function from the atomic model of tubulin. European Biophysics Journal : Ebj. 27: 431-6. PMID 9760724 DOI: 10.1007/s002490050153  1
1998 Nogales E, Downing KH, Amos LA, Löwe J. Tubulin and FtsZ form a distinct family of GTPases. Nature Structural Biology. 5: 451-8. PMID 9628483 DOI: 10.1038/nsb0698-451  1
1998 Downing KH, Nogales E. Tubulin and microtubule structure. Current Opinion in Cell Biology. 10: 16-22. PMID 9484591 DOI: 10.1016/S0955-0674(98)80082-3  1
1998 Nogales E, Wolf SG, Downing KH. Structure of the alpha beta tubulin dimer by electron crystallography. Nature. 391: 199-203. PMID 9428769 DOI: 10.1038/34465  1
1997 Nogales E, Wolf SG, Downing KH. Visualizing the secondary structure of tubulin: three-dimensional map at 4 A. Journal of Structural Biology. 118: 119-27. PMID 9126638 DOI: 10.1006/jsbi.1997.3841  1
1996 Wolf SG, Nogales E, Kikkawa M, Gratzinger D, Hirokawa N, Downing KH. Interpreting a medium-resolution model of tubulin: comparison of zinc-sheet and microtubule structure. Journal of Molecular Biology. 262: 485-501. PMID 8893858 DOI: 10.1006/jmbi.1996.0530  1
1995 Nogales E, Wolf SG, Khan IA, Ludueña RF, Downing KH. Structure of tubulin at 6.5 A and location of the taxol-binding site. Nature. 375: 424-7. PMID 7760939 DOI: 10.1038/375424a0  1
1995 Nogales E, Wolf SG, Zhang SX, Downing KH. Preservation of 2-D crystals of tubulin for electron crystallography. Journal of Structural Biology. 115: 199-208. PMID 7577240 DOI: 10.1006/jsbi.1995.1044  1
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