Year |
Citation |
Score |
2019 |
Sugizaki T, Tanaka KI, Asano T, Kobayashi D, Hino Y, Takafuji A, Shimoda M, Mogushi K, Kawahara M, Mizushima T. Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity. Cell Death Discovery. 5: 146. PMID 31754474 DOI: 10.1038/S41420-019-0226-Y |
0.311 |
|
2018 |
Tanaka KI, Yamakawa N, Yamashita Y, Asano T, Kanda Y, Takafuji A, Kawahara M, Takenaga M, Fukunishi Y, Mizushima T. Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity. Frontiers in Pharmacology. 9: 344. PMID 29692733 DOI: 10.3389/Fphar.2018.00344 |
0.302 |
|
2015 |
Tanaka Y, Ishitsuka Y, Hayasaka M, Yamada Y, Miyata K, Endo M, Kondo Y, Moriuchi H, Irikura M, Tanaka KI, Mizushima T, Oike Y, Irie T. The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 99: 52-62. PMID 26005208 DOI: 10.1016/J.Phrs.2015.05.004 |
0.328 |
|
2015 |
Usui K, Ikeda T, Horibe Y, Nakao M, Hoshino T, Mizushima T. Identification of HSP70-inducing activity in Arnica montana extract and purification and characterization of HSP70-inducers. Journal of Dermatological Science. 78: 67-75. PMID 25724362 DOI: 10.1016/J.Jdermsci.2015.01.014 |
0.309 |
|
2015 |
Kikuchi E, Mori T, Zeniya M, Isobe K, Ishigami-Yuasa M, Fujii S, Kagechika H, Ishihara T, Mizushima T, Sasaki S, Sohara E, Rai T, Uchida S. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters. Journal of the American Society of Nephrology : Jasn. 26: 1525-36. PMID 25377078 DOI: 10.1681/Asn.2014060560 |
0.306 |
|
2014 |
Sawazaki R, Ishihara T, Usui S, Hayashi E, Tahara K, Hoshino T, Higuchi A, Nakamura S, Tsubota K, Mizushima T. Diclofenac protects cultured human corneal epithelial cells against hyperosmolarity and ameliorates corneal surface damage in a rat model of dry eye. Investigative Ophthalmology & Visual Science. 55: 2547-56. PMID 24677100 DOI: 10.1167/Iovs.13-13850 |
0.315 |
|
2014 |
Yamakawa N, Suzuki K, Yamashita Y, Katsu T, Hanaya K, Shoji M, Sugai T, Mizushima T. Structure-activity relationship of celecoxib and rofecoxib for the membrane permeabilizing activity. Bioorganic & Medicinal Chemistry. 22: 2529-34. PMID 24650702 DOI: 10.1016/J.Bmc.2014.02.032 |
0.326 |
|
2013 |
Hoshino T, Suzuki K, Matsushima T, Yamakawa N, Suzuki T, Mizushima T. Suppression of Alzheimer's disease-related phenotypes by geranylgeranylacetone in mice. Plos One. 8: e76306. PMID 24098472 DOI: 10.1371/Journal.Pone.0076306 |
0.312 |
|
2013 |
Tanaka R, Watanabe H, Kodama A, Chuang VT, Ishima Y, Hamasaki K, Tanaka K, Mizushima T, Otagiri M, Maruyama T. Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression. The Journal of Pharmacology and Experimental Therapeutics. 345: 271-83. PMID 23442250 DOI: 10.1124/Jpet.112.201814 |
0.321 |
|
2013 |
Matsuda M, Hoshino T, Yamakawa N, Tahara K, Adachi H, Sobue G, Maji D, Ihn H, Mizushima T. Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice Journal of Investigative Dermatology. 133: 919-928. PMID 23096703 DOI: 10.1038/Jid.2012.383 |
0.324 |
|
2013 |
Nakashita M, Suzuki H, Miura S, Taki T, Uehara K, Mizushima T, Nagata H, Hibi T. Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. Digestive Diseases and Sciences. 58: 354-62. PMID 22918683 DOI: 10.1007/S10620-012-2350-X |
0.306 |
|
2012 |
Suemasu S, Yamakawa N, Ishihara T, Asano T, Tahara K, Tanaka K, Matsui H, Okamoto Y, Otsuka M, Takeuchi K, Suzuki H, Mizushima T. Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity. Biochemical Pharmacology. 84: 1470-81. PMID 23022227 DOI: 10.1016/J.Bcp.2012.09.016 |
0.323 |
|
2012 |
Yamakawa N, Suemasu S, Okamoto Y, Tanaka K, Ishihara T, Asano T, Miyata K, Otsuka M, Mizushima T. Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity. Journal of Medicinal Chemistry. 55: 5143-50. PMID 22404396 DOI: 10.1021/Jm300049G |
0.314 |
|
2012 |
Yamashita Y, Ikeda T, Matsuda M, Maji D, Hoshino T, Mizushima T. Purification and characterization of HSP-inducers from Eupatorium lindleyanum Biochemical Pharmacology. 83: 909-922. PMID 22245466 DOI: 10.1016/J.Bcp.2011.12.040 |
0.347 |
|
2011 |
Namba T, Tanaka KI, Hoshino T, Azuma A, Mizushima T. Suppression of expression of heat shock protein 70 by gefitinib and its contribution to pulmonary fibrosis Plos One. 6. PMID 22096546 DOI: 10.1371/Journal.Pone.0027296 |
0.342 |
|
2011 |
Ishihara T, Suemasu S, Asano T, Tanaka K, Mizushima T. Stimulation of gastric ulcer healing by heat shock protein 70. Biochemical Pharmacology. 82: 728-36. PMID 21736872 DOI: 10.1016/J.Bcp.2011.06.030 |
0.331 |
|
2011 |
Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, Mizushima T. Synthesis and biological evaluation of loxoprofen derivatives. Bioorganic & Medicinal Chemistry. 19: 3299-311. PMID 21570308 DOI: 10.1016/J.Bmc.2011.04.050 |
0.347 |
|
2011 |
Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T. Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5225-34. PMID 21471357 DOI: 10.1523/Jneurosci.5478-10.2011 |
0.305 |
|
2011 |
Tanaka K, Tanaka Y, Suzuki T, Mizushima T. Protective effect of β-(1,3 → 1,6)-D-glucan against irritant-induced gastric lesions. The British Journal of Nutrition. 106: 475-85. PMID 21443814 DOI: 10.1017/S0007114511000365 |
0.319 |
|
2010 |
Mizushima T. Molecular Mechanism for Various Pharmacological Activities of NSAIDS. Pharmaceuticals (Basel, Switzerland). 3: 1614-1636. PMID 27713320 DOI: 10.3390/Ph3051614 |
0.359 |
|
2010 |
Yamakawa N, Suemasu S, Matoyama M, Kimoto A, Takeda M, Tanaka K, Ishihara T, Katsu T, Okamoto Y, Otsuka M, Mizushima T. Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities. Journal of Medicinal Chemistry. 53: 7879-82. PMID 20954731 DOI: 10.1021/Jm101116S |
0.317 |
|
2010 |
Namba T, Hoshino T, Suemasu S, Takarada-Iemata M, Hori O, Nakagata N, Yanaka A, Mizushima T. Suppression of expression of endoplasmic reticulum chaperones by Helicobacter pylori and its role in exacerbation of non-steroidal anti-inflammatory drug-induced gastric lesions Journal of Biological Chemistry. 285: 37302-37313. PMID 20861013 DOI: 10.1074/Jbc.M110.148882 |
0.355 |
|
2010 |
Tanaka K, Tanaka Y, Namba T, Azuma A, Mizushima T. Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice. Biochemical Pharmacology. 80: 920-31. PMID 20513440 DOI: 10.1016/J.Bcp.2010.05.025 |
0.325 |
|
2010 |
Namba T, Tanaka KI, Ito Y, Hoshino T, Matoyama M, Yamakawa N, Isohama Y, Azuma A, Mizushima T. Induction of EMT-like phenotypes by an active metabolite of leflunomide and its contribution to pulmonary fibrosis Cell Death and Differentiation. 17: 1882-1895. PMID 20489727 DOI: 10.1038/Cdd.2010.64 |
0.319 |
|
2010 |
Yamakawa N, Suemasu S, Kimoto A, Arai Y, Ishihara T, Yokomizo K, Okamoto Y, Otsuka M, Tanaka K, Mizushima T. Low direct cytotoxicity of loxoprofen on gastric mucosal cells. Biological & Pharmaceutical Bulletin. 33: 398-403. PMID 20190399 DOI: 10.1248/Bpb.33.398 |
0.357 |
|
2010 |
Hoshino T, Matsuda M, Yamashita Y, Takehara M, Fukuya M, Mineda K, Maji D, Ihn H, Adachi H, Sobue G, Funasaka Y, Mizushima T. Suppression of melanin production by expression of HSP70 Journal of Biological Chemistry. 285: 13254-13263. PMID 20177067 DOI: 10.1074/Jbc.M110.103051 |
0.34 |
|
2010 |
Mizushima T. HSP-dependent protection against gastrointestinal diseases. Current Pharmaceutical Design. 16: 1190-6. PMID 20166990 DOI: 10.2174/138161210790945986 |
0.334 |
|
2010 |
Yamashita Y, Hoshino T, Matsuda M, Kobayashi C, Tominaga A, Nakamura Y, Nakashima K, Yokomizo K, Ikeda T, Mineda K, Maji D, Niwano Y, Mizushima T. HSP70 inducers from Chinese herbs and their effect on melanin production. Experimental Dermatology. 19: e340-2. PMID 20163455 DOI: 10.1111/J.1600-0625.2009.01061.X |
0.318 |
|
2010 |
Ishihara T, Tanaka K, Tashiro S, Yoshida K, Mizushima T. Protective effect of rebamipide against celecoxib-induced gastric mucosal cell apoptosis. Biochemical Pharmacology. 79: 1622-33. PMID 20132796 DOI: 10.1016/J.Bcp.2010.01.030 |
0.339 |
|
2010 |
Matsuda M, Hoshino T, Yamashita Y, Tanaka KI, Maji D, Sato K, Adachi H, Sobue G, Ihn H, Funasaka Y, Mizushima T. Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70 Journal of Biological Chemistry. 285: 5848-5858. PMID 20018843 DOI: 10.1074/Jbc.M109.063453 |
0.343 |
|
2009 |
Tanaka K, Mizushima T. Protective role of HSF1 and HSP70 against gastrointestinal diseases. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 25: 668-76. PMID 20021227 DOI: 10.3109/02656730903213366 |
0.335 |
|
2009 |
Asano T, Tanaka K, Yamakawa N, Adachi H, Sobue G, Goto H, Takeuchi K, Mizushima T. HSP70 confers protection against indomethacin-induced lesions of the small intestine. The Journal of Pharmacology and Experimental Therapeutics. 330: 458-67. PMID 19458285 DOI: 10.1124/Jpet.109.152181 |
0.334 |
|
2009 |
Suemasu S, Tanaka K, Namba T, Ishihara T, Katsu T, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T. A role for HSP70 in protecting against indomethacin-induced gastric lesions. The Journal of Biological Chemistry. 284: 19705-15. PMID 19439408 DOI: 10.1074/Jbc.M109.006817 |
0.358 |
|
2009 |
Namba T, Tanaka KI, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T. Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis American Journal of Pathology. 174: 1786-1798. PMID 19359519 DOI: 10.2353/Ajpath.2009.080864 |
0.335 |
|
2009 |
Tanaka K, Suemasu S, Ishihara T, Tasaka Y, Arai Y, Mizushima T. Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis. European Journal of Pharmacology. 603: 120-32. PMID 19101538 DOI: 10.1016/J.Ejphar.2008.11.058 |
0.34 |
|
2009 |
Namba T, Homan T, Nishimura T, Mima S, Hoshino T, Mizushima T. Up-regulation of S100P expression by non-steroidal anti-inflammatory drugs and its role in anti-tumorigenic effects Journal of Biological Chemistry. 284: 4158-4167. PMID 19073601 DOI: 10.1074/Jbc.M806051200 |
0.343 |
|
2009 |
Makise M, Takehara M, Kuniyasu A, Matsui N, Nakayama H, Mizushima T. Linkage between phosphorylation of the origin recognition complex and its ATP binding activity in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 3396-407. PMID 19068484 DOI: 10.1074/Jbc.M804293200 |
0.332 |
|
2009 |
Asano T, Tanaka K, Mizushima T. W1675 A Protective Role for HSP70 Against Indomethacin-Induced Small Intestinal Lesions Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)63299-6 |
0.329 |
|
2009 |
Suemasu S, Tanaka K, Mizushima T. W1561 A Protective Role of Heat Shock Proteins Against Non-Steroidal Anti-Inflammatory Drug-Induced Gastric Lesions Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)63186-3 |
0.339 |
|
2009 |
Suemasu S, Ishihara T, Asano T, Tanaka K, Mizushima T. M1836 A Protective Role of HSPS Against Various Gastrointestinal Diseases and Application of HSP-Inducing Drugs for These Diseases Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)62645-7 |
0.317 |
|
2008 |
Mima S, Takehara M, Takada H, Nishimura T, Hoshino T, Mizushima T. NSAIDs suppress the expression of claudin-2 to promote invasion activity of cancer cells Carcinogenesis. 29: 1994-2000. PMID 18586689 DOI: 10.1093/Carcin/Bgn134 |
0.339 |
|
2008 |
Takehara M, Makise M, Takenaka H, Asano T, Mizushima T. Analysis of mutant origin recognition complex with reduced ATPase activity in vivo and in vitro. The Biochemical Journal. 413: 535-43. PMID 18393942 DOI: 10.1042/Bj20070484 |
0.36 |
|
2008 |
Mizushima T. [Strategy for development of NSAIDs with lower risk for side effects]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 128: 255-61. PMID 18239373 DOI: 10.1248/Yakushi.128.255 |
0.354 |
|
2008 |
Makise M, Matsui N, Yamairi F, Takahashi N, Takehara M, Asano T, Mizushima T. Analysis of origin recognition complex in saccharomyces cerevisiae by use of Degron mutants. Journal of Biochemistry. 143: 455-65. PMID 18211918 DOI: 10.1093/Jb/Mvn005 |
0.305 |
|
2008 |
Matsuo T, Chen J, Minato Y, Ogawa W, Mizushima T, Kuroda T, Tsuchiya T. SmdAB, a heterodimeric ABC-Type multidrug efflux pump, in Serratia marcescens. Journal of Bacteriology. 190: 648-54. PMID 18024518 DOI: 10.1128/Jb.01513-07 |
0.365 |
|
2008 |
Mizushima T. Development of new type of NSAIDs with lower gastric side effects Inflammation and Regeneration. 28: 100-104. DOI: 10.2492/Inflammregen.28.100 |
0.39 |
|
2008 |
Tanaka K, Mizushima T. 510 Protective Role for HSF1 and Hsps Against Both Irritant-Induced Gastric Lesions and DSS-Induced Colitis, An Animal Model for Human IBD Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60334-0 |
0.306 |
|
2007 |
Matsuo T, Hayashi K, Morita Y, Koterasawa M, Ogawa W, Mizushima T, Tsuchiya T, Kuroda T. VmeAB, an RND-type multidrug efflux transporter in Vibrio parahaemolyticus. Microbiology (Reading, England). 153: 4129-37. PMID 18048926 DOI: 10.1099/Mic.0.2007/009597-0 |
0.32 |
|
2007 |
Asano T, Makise M, Takehara M, Mizushima T. Interaction between ORC and Cdt1p of Saccharomyces cerevisiae. Fems Yeast Research. 7: 1256-62. PMID 17825064 DOI: 10.1111/J.1567-1364.2007.00299.X |
0.315 |
|
2007 |
Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T. Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis. The Journal of Biological Chemistry. 282: 23240-52. PMID 17556362 DOI: 10.1074/Jbc.M704081200 |
0.337 |
|
2007 |
Mizushima T. Various stress proteins protect gastric mucosal cells against non-steroidal anti-inflammatory drugs. Inflammopharmacology. 15: 67-73. PMID 17450445 DOI: 10.1007/S10787-006-1560-2 |
0.371 |
|
2007 |
Shahcheraghi F, Minato Y, Chen J, Mizushima T, Ogawa W, Kuroda T, Tsuchiya T. Molecular cloning and characterization of a multidrug efflux pump, SmfY, from Serratia marcescens. Biological & Pharmaceutical Bulletin. 30: 798-800. PMID 17409524 DOI: 10.1248/Bpb.30.798 |
0.329 |
|
2007 |
Ishihara T, Hoshino T, Namba T, Tanaka Ki, Mizushima T. Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis Biochemical and Biophysical Research Communications. 356: 711-717. PMID 17368424 DOI: 10.1016/J.Bbrc.2007.03.034 |
0.341 |
|
2007 |
Mima S, Ushijima H, Hwang HJ, Tsutsumi S, Makise M, Yamaguchi Y, Tsuchiya T, Mizushima H, Mizushima T. Identification of the TPO1 gene in yeast, and its human orthologue TETRAN, which cause resistance to NSAIDs. Febs Letters. 581: 1457-63. PMID 17362938 DOI: 10.1016/J.Febslet.2007.03.001 |
0.33 |
|
2007 |
Tanaka KI, Tsutsumi S, Arai Y, Hoshino T, Suzuki K, Takaki E, Ito T, Takeuchi K, Nakai A, Mizushima T. Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions Molecular Pharmacology. 71: 985-993. PMID 17189318 DOI: 10.1124/Mol.106.033282 |
0.35 |
|
2007 |
Namba T, Hoshino T, Tanaka KI, Tsutsumi S, Ishihara T, Mima S, Suzuki K, Ogawa S, Mizushima T. Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells Molecular Pharmacology. 71: 860-870. PMID 17167033 DOI: 10.1124/Mol.106.027698 |
0.35 |
|
2007 |
Makise M, Takahashi N, Matsuda K, Yamairi F, Suzuki K, Tsuchiya T, Mizushima T. Mechanism for the degradation of origin recognition complex containing Orc5p with a defective Walker A motif and its suppression by over-production of Orc4p in yeast cells. The Biochemical Journal. 402: 397-403. PMID 17107343 DOI: 10.1042/Bj20060841 |
0.314 |
|
2006 |
Aburaya M, Tanaka KI, Hoshino T, Tsutsumi S, Suzuki K, Makise M, Akagi R, Mizushima T. Heme oxygenase-1 protects gastric mucosal cells against non-steroidal anti-inflammatory drugs Journal of Biological Chemistry. 281: 33422-33432. PMID 16945925 DOI: 10.1074/Jbc.M602074200 |
0.362 |
|
2006 |
Yamada Y, Shiota S, Mizushima T, Kuroda T, Tsuchiya T. Functional gene cloning and characterization of MdeA, a multidrug efflux pump from Staphylococcus aureus. Biological & Pharmaceutical Bulletin. 29: 801-4. PMID 16595922 DOI: 10.1248/Bpb.29.801 |
0.355 |
|
2006 |
Tsutsumi S, Namba T, Tanaka KI, Arai Y, Ishihara T, Aburaya M, Mima S, Hoshino T, Mizushima T. Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells Oncogene. 25: 1018-1029. PMID 16205636 DOI: 10.1038/Sj.Onc.1209139 |
0.361 |
|
2005 |
Mima T, Sekiya H, Mizushima T, Kuroda T, Tsuchiya T. Gene Cloning and Properties of the RND‐Type Multidrug Efflux Pumps MexPQ‐OpmE and MexMN‐OprM from Pseudomonas aeruginosa Microbiology and Immunology. 49: 999-1002. PMID 16301811 DOI: 10.1111/J.1348-0421.2005.Tb03696.X |
0.326 |
|
2005 |
Tomisato W, Tanaka KI, Tsutsumi S, Hoshino T, Yokomizo K, Suzuki K, Katsu T, Mizushima T. Low direct cytotoxicity and cytoprotective effects of nitric oxide releasing indomethacin Digestive Diseases and Sciences. 50: 1927-1937. PMID 16187199 DOI: 10.1007/S10620-005-2963-4 |
0.351 |
|
2005 |
Arai Y, Tanaka KI, Ushijima H, Tomisato W, Tsutsumi S, Aburaya M, Hoshino T, Yokomizo K, Suzuki K, Katsu T, Tsuchiya T, Mizushima T. Low direct cytotoxicity of nabumetone on gastric mucosal cells Digestive Diseases and Sciences. 50: 1641-1646. PMID 16133963 DOI: 10.1007/S10620-005-2909-X |
0.343 |
|
2005 |
Ogawa W, Li DW, Yu P, Begum A, Mizushima T, Kuroda T, Tsuchiya T. Multidrug resistance in Klebsiella pneumoniae MGH78578 and cloning of genes responsible for the resistance Biological & Pharmaceutical Bulletin. 28: 1505-1508. PMID 16079502 DOI: 10.1248/Bpb.28.1505 |
0.301 |
|
2005 |
Ushijima H, Tanaka KI, Takeda M, Katsu T, Mima S, Mizushima T. Geranylgeranylacetone Protects Membranes against Nonsteroidal Anti-Inflammatory Drugs Molecular Pharmacology. 68: 1156-1161. PMID 16046660 DOI: 10.1124/Mol.105.015784 |
0.349 |
|
2005 |
Tanaka KI, Tomisato W, Hoshino T, Ishihara T, Namba T, Aburaya M, Katsu T, Suzuki K, Tsutsumi S, Mizushima T. Involvement of intracellular Ca2+ levels in nonsteroidal anti-inflammatory drug-induced apoptosis Journal of Biological Chemistry. 280: 31059-31067. PMID 15987693 DOI: 10.1074/Jbc.M502956200 |
0.335 |
|
2005 |
Suzuki K, Okawara T, Higashijima T, Yokomizo K, Mizushima T, Otsuka M. Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 15: 2065-8. PMID 15808469 DOI: 10.1016/J.Bmcl.2005.02.052 |
0.306 |
|
2005 |
Mima S, Tsutsumi S, Ushijima H, Takeda M, Fukuda I, Yokomizo K, Suzuki K, Sano K, Nakanishi T, Tomisato W, Tsuchiya T, Mizushima T. Induction of Claudin-4 by Nonsteroidal Anti-inflammatory Drugs and Its Contribution to Their Chemopreventive Effect Cancer Research. 65: 1868-1876. PMID 15753385 DOI: 10.1158/0008-5472.Can-04-2770 |
0.367 |
|
2004 |
Tomisato W, Tanaka KI, Katsu T, Kakuta H, Sasaki K, Tsutsumi S, Hoshino T, Aburaya M, Li D, Tsuchiya T, Suzuki K, Yokomizo K, Mizushima T. Membrane permeabilization by non-steroidal anti-inflammatory drugs Biochemical and Biophysical Research Communications. 323: 1032-1039. PMID 15381103 DOI: 10.1016/J.Bbrc.2004.08.205 |
0.311 |
|
2004 |
Tanaka KI, Tomisato W, Tsutsumi S, Hoshino T, Tsuchiya T, Mizushima T. Cytotoxic synergy between indomethacin and hydrochloric acid in gastric mucosal cells Biological and Pharmaceutical Bulletin. 27: 1188-1192. PMID 15305019 DOI: 10.1248/Bpb.27.1188 |
0.343 |
|
2004 |
Tsutsumi S, Gotoh T, Tomisato W, Mima S, Hoshino T, Hwang HJ, Takenaka H, Tsuchiya T, Mori M, Mizushima T. Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis Cell Death and Differentiation. 11: 1009-1016. PMID 15131590 DOI: 10.1038/Sj.Cdd.4401436 |
0.366 |
|
2004 |
Kuroda T, Fujita N, Utsugi J, Kuroda M, Mizushima T, Tsuchiya T. A major Li(+) extrusion system NhaB of Pseudomonas aeruginosa : comparison with the major Na(+) extrusion system NhaP. Microbiology and Immunology. 48: 243-250. PMID 15107534 DOI: 10.1111/J.1348-0421.2004.Tb03520.X |
0.318 |
|
2004 |
Tanaka KI, Nishimoto K, Tomisato W, Tsutsumi S, Hoshino T, Tsuchiya T, Mizushima T. Adaptive cytoprotection induced by pretreatment with ethanol protects against gastric cell damage by NSAIDs Digestive Diseases and Sciences. 49: 210-217. PMID 15104359 DOI: 10.1023/B:Ddas.0000017440.46863.56 |
0.321 |
|
2004 |
Tomisato W, Tsutsumi S, Hoshino T, Hwang HJ, Mio M, Tsuchiya T, Mizushima T. Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions Biochemical Pharmacology. 67: 575-585. PMID 15037209 DOI: 10.1016/J.Bcp.2003.09.020 |
0.334 |
|
2004 |
He GX, Kuroda T, Mima T, Morita Y, Mizushima T, Tsuchiya T. An H+-Coupled Multidrug Efflux Pump, PmpM, a Member of the MATE Family of Transporters, from Pseudomonas aeruginosa Journal of Bacteriology. 186: 262-265. PMID 14679249 DOI: 10.1128/Jb.186.1.262-265.2004 |
0.304 |
|
2004 |
Takahashi N, Yamaguchi Y, Yamairi F, Makise M, Takenaka H, Tsuchiya T, Mizushima T. Analysis on origin recognition complex containing Orc5p with defective Walker A motif. Journal of Biological Chemistry. 279: 8469-8477. PMID 14625297 DOI: 10.1074/Jbc.M305531200 |
0.316 |
|
2003 |
Xu XJ, Su XZ, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. Molecular Cloning and Characterization of the HmrM Multidrug Efflux Pump from Haemophilus influenzae Rd Microbiology and Immunology. 47: 937-943. PMID 14695443 DOI: 10.1111/J.1348-0421.2003.Tb03467.X |
0.344 |
|
2003 |
Lee EW, Huda MN, Kuroda T, Mizushima T, Tsuchiya T. EfrAB, an ABC Multidrug Efflux Pump in Enterococcus faecalis Antimicrobial Agents and Chemotherapy. 47: 3733-3738. PMID 14638474 DOI: 10.1128/Aac.47.12.3733-3738.2003 |
0.309 |
|
2003 |
Tsutsumi S, Mima S, Tomisato W, Hoshino T, Tsuchiya T, Mizushima T. Molecular mechanism of adaptive cytoprotection induced by ethanol in human gastric cells Experimental Biology and Medicine. 228: 1089-1095. PMID 14530521 DOI: 10.1177/153537020322800917 |
0.326 |
|
2003 |
Li Y, Mima T, Komori Y, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. A new member of the tripartite multidrug efflux pumps, MexVW–OprM, in Pseudomonas aeruginosa Journal of Antimicrobial Chemotherapy. 52: 572-575. PMID 12951344 DOI: 10.1093/Jac/Dkg390 |
0.326 |
|
2003 |
Sekiya H, Mima T, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. Functional Cloning and Characterization of a Multidrug Efflux Pump, MexHI-OpmD, from a Pseudomonas aeruginosa Mutant Antimicrobial Agents and Chemotherapy. 47: 2990-2992. PMID 12937010 DOI: 10.1128/Aac.47.9.2990-2992.2003 |
0.341 |
|
2003 |
Huda NM, Chen J, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. Gene Cloning and Characterization of VcrM, a Na+‐Coupled Multidrug Efflux Pump, from Vibrio cholerae Non‐O1 Microbiology and Immunology. 47: 419-427. PMID 12906102 DOI: 10.1111/J.1348-0421.2003.Tb03379.X |
0.351 |
|
2003 |
Huda N, Lee EW, Chen J, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. Molecular Cloning and Characterization of an ABC Multidrug Efflux Pump, VcaM, in Non-O1 Vibrio cholerae Antimicrobial Agents and Chemotherapy. 47: 2413-2417. PMID 12878498 DOI: 10.1128/Aac.47.8.2413-2417.2003 |
0.353 |
|
2003 |
Chen J, Kuroda T, Huda N, Mizushima T, Tsuchiya T. An RND-type multidrug efflux pump SdeXY from Serratia marcescens. Journal of Antimicrobial Chemotherapy. 52: 176-179. PMID 12837741 DOI: 10.1093/Jac/Dkg308 |
0.322 |
|
2003 |
Morita Y, Murata T, Mima T, Shiota S, Kuroda T, Mizushima T, Gotoh N, Nishino T, Tsuchiya T. Induction of mexCD-oprJ operon for a multidrug efflux pump by disinfectants in wild-type Pseudomonas aeruginosa PAO1 Journal of Antimicrobial Chemotherapy. 51: 991-994. PMID 12654738 DOI: 10.1093/Jac/Dkg173 |
0.312 |
|
2003 |
Lee E, Chen J, Huda MN, Kuroda T, Mizushima T, Tsuchiya T. Functional cloning and expression of emeA, and characterization of EmeA, a multidrug efflux pump from Enterococcus faecalis. Biological & Pharmaceutical Bulletin. 26: 266-270. PMID 12576692 DOI: 10.1248/Bpb.26.266 |
0.36 |
|
2003 |
Hoshino T, Tsutsumi S, Tomisato W, Hwang HJ, Tsuchiya T, Mizushima T. Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation Journal of Biological Chemistry. 278: 12752-12758. PMID 12556459 DOI: 10.1074/Jbc.M212097200 |
0.354 |
|
2003 |
Hoshino T, Takano T, Tomisato W, Tsutsumi S, Hwang HJ, Koura Y, Nishimoto K, Tsuchiya T, Mizushima T. Effects of sucralfate on gastric irritant-induced necrosis and apoptosis in cultured guinea pig gastric mucosal cells Biological and Pharmaceutical Bulletin. 26: 24-27. PMID 12520166 DOI: 10.1248/Bpb.26.24 |
0.339 |
|
2003 |
Mizushima T, Tsutsumi S, Hoshino T, Tomisato W. Protection of Gastric Mucosal Cells from Apoptosis and Necrosis by Induction of HSP and PGE2 Japanese Journal of Hyperthermic Oncology. 19: 67-78. DOI: 10.3191/Thermalmedicine.19.67 |
0.327 |
|
2003 |
Tomisato W, Mizushima T. Involvement of cyclooxygenase-independent direct cytotoxic effect of NSAIDs in NSAIDs-induced gastric lesion Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80865-X |
0.304 |
|
2002 |
Hoshino T, Takano T, Tsutsumi S, Tomisato W, Tsuchiya T, Mizushima T. Effects of prostaglandin E2 on gastric irritant-induced apoptosis Digestive Diseases and Sciences. 47: 2370-2379. PMID 12395910 DOI: 10.1023/A:1020164000898 |
0.335 |
|
2002 |
Makise M, Mima S, Katsu T, Tsuchiya T, Mizushima T. Acidic phospholipids inhibit the DNA‐binding activity of DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli Molecular Microbiology. 46: 245-256. PMID 12366847 DOI: 10.1046/J.1365-2958.2002.03161.X |
0.313 |
|
2002 |
Tomisato W, Hoshino T, Tsutsumi S, Tsuchiya T, Mizushima T. Maturation-associated increase in sensitivity of cultured guinea pig gastric pit cells to hydrogen peroxide Digestive Diseases and Sciences. 47: 2125-2133. PMID 12353867 DOI: 10.1023/A:1019653719397 |
0.303 |
|
2002 |
Takano T, Tsutsumi S, Tomisato W, Hoshino T, Tsuchiya T, Mizushima T. Geranylgeranylacetone protects guinea pig gastric mucosal cells from gastric stressor-induced apoptosis Digestive Diseases and Sciences. 47: 1546-1553. PMID 12141815 DOI: 10.1023/A:1015819203084 |
0.373 |
|
2002 |
Koterasawa M, Mima S, Makise M, Tsuchiya T, Mizushima T. Mutational analysis of conserved hydrophobic amino acid residues in the N-terminal region of DnaA protein. Biological & Pharmaceutical Bulletin. 25: 913-915. PMID 12132668 DOI: 10.1248/Bpb.25.913 |
0.335 |
|
2002 |
Kim YM, Ogawa W, Tamai E, Kuroda T, Mizushima T, Tsuchiya T. Purification, reconstitution, and characterization of Na(+)/serine symporter, SstT, of Escherichia coli. Journal of Biochemistry. 132: 71-6. PMID 12097162 DOI: 10.1093/Oxfordjournals.Jbchem.A003201 |
0.328 |
|
2002 |
Tsutsumi S, Tomisato W, Takano T, Rokutan K, Tsuchiya T, Mizushima T. Gastric irritant-induced apoptosis in guinea pig gastric mucosal cells in primary culture. Biochimica Et Biophysica Acta. 1589: 168-180. PMID 12007792 DOI: 10.1016/S0167-4889(02)00171-4 |
0.334 |
|
2002 |
Lee JR, Takenaka H, Takahashi N, Makise M, Yamaguchi Y, Tsuchiya T, Mizushima T. Acidic phospholipids with unsaturated fatty acids inhibit the binding of origin recognition complex to origin DNA. Journal of Biochemistry. 131: 541-546. PMID 11926991 DOI: 10.1093/Oxfordjournals.Jbchem.A003132 |
0.308 |
|
2002 |
Makise M, Tsuchiya T, Mizushima T. Sequence-Independent DNA Binding Activity of DnaA Protein, the Initiator of Chromosomal DNA Replication in Escherichia coli Journal of Biochemistry. 131: 419-425. PMID 11872171 DOI: 10.1093/Oxfordjournals.Jbchem.A003117 |
0.313 |
|
2002 |
Makise M, Mima S, Koterasawa M, Tsuchiya T, Mizushima T. Biochemical analysis of DnaA protein with mutations in both Arg328 and Lys372 Biochemical Journal. 362: 453-458. PMID 11853554 DOI: 10.1042/0264-6021:3620453 |
0.356 |
|
2002 |
Lee JR, Makise M, Takenaka H, Takahashi N, Yamaguchi Y, Tsuchiya T, Mizushima T. Inhibitory effects of acidic phospholipids on the binding of origin-recognition complex to origin DNA. Biochemical Journal. 362: 395-399. PMID 11853548 DOI: 10.1042/Bj3620395 |
0.329 |
|
2002 |
Tsutsumi S, Haruna R, Tomisato W, Takano T, Hoshino T, Tsuchiya T, Mizushima T. Effects of prostaglandins on spontaneous apoptosis in gastric mucosal cells Digestive Diseases and Sciences. 47: 84-89. PMID 11837738 DOI: 10.1023/A:1013267504584 |
0.351 |
|
2002 |
Takahashi N, Tsutsumi S, Tsuchiya T, Stillman B, Mizushima T. Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro. The Journal of Biological Chemistry. 277: 16033-40. PMID 11827963 DOI: 10.1074/Jbc.M108615200 |
0.543 |
|
2001 |
Morita Y, Kimura N, Mima T, Mizushima T, Tsuchiya T. Roles of MexXY- and MexAB-multidrug efflux pumps in intrinsic multidrug resistance of Pseudomonas aeruginosa PAO1. Journal of General and Applied Microbiology. 47: 27-32. PMID 12483565 DOI: 10.2323/Jgam.47.27 |
0.307 |
|
2001 |
Gouda T, Kuroda M, Hiramatsu T, Nozaki K, Kuroda T, Mizushima T, Tsuchiya T. nhaG Na(+)/H(+) antiporter gene of Bacillus subtilis ATCC9372, which is missing in the complete genome sequence of strain 168, and properties of the antiporter. Journal of Biochemistry. 130: 711-717. PMID 11686935 DOI: 10.1093/Oxfordjournals.Jbchem.A003038 |
0.31 |
|
2001 |
Huda MN, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. Na+-driven multidrug efflux pump VcmA from Vibrio cholerae non-O1, a non-halophilic bacterium Fems Microbiology Letters. 203: 235-239. PMID 11583854 DOI: 10.1111/J.1574-6968.2001.Tb10847.X |
0.338 |
|
2001 |
Tomisato W, Tsutsumi S, Rokutan K, Tsuchiya T, Mizushima T. NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture American Journal of Physiology-Gastrointestinal and Liver Physiology. 281. PMID 11557530 DOI: 10.1152/Ajpgi.2001.281.4.G1092 |
0.363 |
|
2001 |
Tomisato W, Tsutsumi S, Tsuchiya T, Mizushima T. Geranylgeranylacetone Protects Guinea Pig Gastric Mucosal Cells from Gastric Stressor-Induced Necrosis by Induction of Heat-Shock Proteins Biological & Pharmaceutical Bulletin. 24: 887-891. PMID 11510479 DOI: 10.1248/Bpb.24.887 |
0.344 |
|
2001 |
Morita Y, Komori Y, Mima T, Kuroda T, Mizushima T, Tsuchiya T. Construction of a series of mutants lacking all of the four major mex operons for multidrug efflux pumps or possessing each one of the operons from Pseudomonas aeruginosa PAO1: MexCD-OprJ is an inducible pump. Fems Microbiology Letters. 202: 139-143. PMID 11506922 DOI: 10.1111/J.1574-6968.2001.Tb10794.X |
0.336 |
|
2001 |
Makise M, Mima S, Tsuchiya T, Mizushima T. Molecular Mechanism for Functional Interaction between DnaA Protein and Acidic Phospholipids IDENTIFICATION OF IMPORTANT AMINO ACIDS Journal of Biological Chemistry. 276: 7450-7456. PMID 11102450 DOI: 10.1074/Jbc.M009643200 |
0.329 |
|
2000 |
Morita Y, Kataoka A, Shiota S, Mizushima T, Tsuchiya T. NorM of Vibrio parahaemolyticus Is an Na+-Driven Multidrug Efflux Pump Journal of Bacteriology. 182: 6694-6697. PMID 11073914 DOI: 10.1128/Jb.182.23.6694-6697.2000 |
0.312 |
|
2000 |
Rokutan K, Teshima S, Kawai T, Kawahara T, Kusumoto K, Mizushima T, Kishi K. Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase Journal of Gastroenterology. 35: 673-681. PMID 11023038 DOI: 10.1007/S005350070046 |
0.326 |
|
2000 |
Tomisato W, Takahashi N, Komoto C, Rokutan K, Tsuchiya T, Mizushima T. Geranylgeranylacetone Protects Cultured Guinea Pig Gastric Mucosal Cells from Indomethacin Digestive Diseases and Sciences. 45: 1674-1679. PMID 11007124 DOI: 10.1023/A:1005597902470 |
0.381 |
|
2000 |
Mizushima T, Takahashi N, Stillman B. Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro. Genes & Development. 14: 1631-41. PMID 10887157 DOI: 10.1101/Gad.14.13.1631 |
0.557 |
|
2000 |
Masaoka Y, Ueno Y, Morita Y, Kuroda T, Mizushima T, Tsuchiya T. A Two-Component Multidrug Efflux Pump, EbrAB, in Bacillus subtilis Journal of Bacteriology. 182: 2307-2310. PMID 10735876 DOI: 10.1128/Jb.182.8.2307-2310.2000 |
0.313 |
|
2000 |
Mizushima T. Site-directed mutational analysis of DnaA protein, the initiator of chromosomal DNA replication in E. coli. Journal of Biochemistry. 127: 1-7. PMID 10731659 DOI: 10.1093/Oxfordjournals.Jbchem.A022569 |
0.356 |
|
2000 |
Tsutsumi S, Rokutan K, Tsuchiya T, Mizushima T. Spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric mucosal cells Digestive Diseases and Sciences. 45: 291-297. PMID 10711441 DOI: 10.1023/A:1005404424698 |
0.351 |
|
2000 |
Makise M, Mima S, Tsuchiya T, Mizushima T. Identification of amino acids involved in the functional interaction between DnaA protein and acidic phospholipids. Journal of Biological Chemistry. 275: 4513-4518. PMID 10660626 DOI: 10.1074/Jbc.275.6.4513 |
0.339 |
|
2000 |
KONDO T, MIMA S, FUKUMA N, SEKIMIZU K, TSUCHIYA T, MIZUSHIMA T. Suppression of temperature-sensitivity of a dnaA46 mutant by excessive DNA supercoiling Biochemical Journal. 348: 375. DOI: 10.1042/0264-6021:3480375 |
0.33 |
|
1999 |
Makise M, Sakamoto K, Tsuchiya T, Mizushima T. Identification of a high-copy-number plasmid suppressor of a lethal phenotype caused by mutant DnaA protein which has decreased intrinsic ATPase activity. Biological & Pharmaceutical Bulletin. 22: 904-909. PMID 10513610 DOI: 10.1248/Bpb.22.904 |
0.349 |
|
1999 |
Tsutsumi S, Rokutan K, Tsuchiya T, Mizushima T. Geranylgeranylacetone suppresses spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric pit cells. Biological & Pharmaceutical Bulletin. 22: 886-887. PMID 10480334 DOI: 10.1248/Bpb.22.886 |
0.384 |
|
1999 |
Mima S, Yamagachi Y, Kondo T, Tsuchiya T, Mizushima T. Role of the amino-terminal region of the DnaA protein in opening of the duplex DNA at the oriC region Fems Microbiology Letters. 176: 163-167. PMID 10418142 DOI: 10.1111/J.1574-6968.1999.Tb13657.X |
0.332 |
|
1999 |
Mizushima T, Tsutsumi S, Rokutan K, Tsuchiya T. Suppression of ethanol-induced apoptotic DNA fragmentation by geranylgeranylacetone in cultured guinea pig gastric mucosal cells. Digestive Diseases and Sciences. 44: 510-514. PMID 10080142 DOI: 10.1023/A:1026692920848 |
0.354 |
|
1999 |
Mine T, Morita Y, Kataoka A, Mizushima T, Tsuchiya T. Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 43: 415-417. PMID 9925549 DOI: 10.1128/Aac.43.2.415 |
0.302 |
|
1999 |
Ohba A, Inoue R, Akimitsu N, Mizushima T, Sekimizu K. Identification of proteins whose amounts are altered by mutation in the pgsA gene of Escherichia coli. Biological & Pharmaceutical Bulletin. 21: 1139-41. PMID 9853401 DOI: 10.1248/Bpb.21.1139 |
0.321 |
|
1999 |
Yamaguchi Y, Hase M, Makise M, Mima S, Yoshimi T, Ishikawa Y, Tsuchiya T, Mizushima T. Involvement of Arg-328, Arg-334 and Arg-342 of DnaA protein in the functional interaction with acidic phospholipids. Biochemical Journal. 340: 433-438. DOI: 10.1042/0264-6021:3400433 |
0.308 |
|
1998 |
Hiramatsu T, Kodama K, Kuroda T, Mizushima T, Tsuchiya T. A Putative Multisubunit Na+/H+ Antiporter from Staphylococcus aureus Journal of Bacteriology. 180: 6642-6648. PMID 9852009 DOI: 10.1128/Jb.180.24.6642-6648.1998 |
0.315 |
|
1998 |
Hase M, Yoshimi T, Ishikawa Y, Ohba A, Guo L, Mima S, Makise M, Yamaguchi Y, Tsuchiya T, Mizushima T. Site-directed Mutational Analysis for the Membrane Binding of DnaA Protein IDENTIFICATION OF AMINO ACIDS INVOLVED IN THE FUNCTIONAL INTERACTION BETWEEN DnaA PROTEIN AND ACIDIC PHOSPHOLIPIDS* Journal of Biological Chemistry. 273: 28651-28656. PMID 9786858 DOI: 10.1074/Jbc.273.44.28651 |
0.321 |
|
1998 |
Mizushima T. [Function of DnaA protein, the initiator for chromosomal DNA replication in E. coli] Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan. 118: 257-271. PMID 9720453 DOI: 10.1248/Yakushi1947.118.7_257 |
0.323 |
|
1998 |
Suzuki E, Kondo T, Makise M, Mima S, Sakamoto K, Tsuchiya T, Mizushima T. Alteration in levels of unsaturated fatty acids in mutants of Escherichia coli defective in DNA replication Biological & Pharmaceutical Bulletin. 21: 657-661. PMID 9703244 DOI: 10.1248/Bpb.21.657 |
0.316 |
|
1998 |
Mizushima T, Takaki T, Kubota T, Tsuchiya T, Miki T, Katayama T, Sekimizu K. Site-directed mutational analysis for the ATP binding of DnaA protein. Functions of two conserved amino acids (Lys-178 and Asp-235) located in the ATP-binding domain of DnaA protein in vitro and in vivo. The Journal of Biological Chemistry. 273: 20847-51. PMID 9694830 DOI: 10.1074/Jbc.273.33.20847 |
0.344 |
|
1998 |
Morita Y, Kodama K, Shiota S, Mine T, Kataoka A, Mizushima T, Tsuchiya T. NorM, a Putative Multidrug Efflux Protein, of Vibrio parahaemolyticus and Its Homolog in Escherichia coli Antimicrobial Agents and Chemotherapy. 42: 1778-1782. PMID 9661020 DOI: 10.1128/Aac.42.7.1778 |
0.349 |
|
1998 |
Mine T, Morita Y, Kataoka A, Mizushima T, Tsuchiya T. Evidence for chloramphenicol/H+ antiport in cmr (MdfA) system of Escherichia coli and properties of the antiporter Journal of Biochemistry. 124: 187-193. PMID 9644262 DOI: 10.1093/Oxfordjournals.Jbchem.A022078 |
0.332 |
|
1998 |
Hase M, Ishikawa Y, Sekimizu K, Tsuchiya T, Mizushima T. Effect of glycerol on the affinity of DnaA protein for ATP in the presence of cardiolipin. Journal of Biochemistry. 123: 680-3. PMID 9538261 DOI: 10.1093/Oxfordjournals.Jbchem.A021991 |
0.307 |
|
1998 |
Nozaki K, Kuroda T, Mizushima T, Tsuchiya T. A New Na+/H+ Antiporter, Nhad, Of Vibrio Parahaemolyticus Biochimica Et Biophysica Acta. 1369: 213-220. PMID 9518619 DOI: 10.1016/S0005-2736(97)00223-X |
0.319 |
|
1998 |
Sakamoto K, Makise M, Tsuchiya T, Mizushima T. Effect of environmental factors on the dominant lethality caused by expression of a mutated DnaA protein with decreased intrinsic ATPase activity Fems Microbiology Letters. 159: 93-97. PMID 9485598 DOI: 10.1111/J.1574-6968.1998.Tb12846.X |
0.352 |
|
1998 |
Kurokawa K, Mizushima T, Kubota T, Tsuchiya T, Katayama T, Sekimizu K. A stimulation factor for hydrolysis of ATP bound to DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli. Biochemical and Biophysical Research Communications. 243: 90-5. PMID 9473485 DOI: 10.1006/Bbrc.1997.8069 |
0.327 |
|
1998 |
Shah GH, Kataoka K, Ueno A, Ohtsuka Y, Mizushima T, Sekimizu K. Psychotropic drugs and local anesthetics restore cardiolipin-inhibited mammalian DNA topoisomerase I activity. Biological & Pharmaceutical Bulletin. 20: 1233-4. PMID 9448094 DOI: 10.1248/Bpb.20.1233 |
0.353 |
|
1997 |
Katayama T, Akimitsu N, Mizushima T, Miki T, Sekimizu K. Overinitiation of chromosome replication in the Escherichia coli dnaAcos mutant depends on activation of oriC function by the dam gene product. Molecular Microbiology. 25: 661-70. PMID 9379896 DOI: 10.1046/J.1365-2958.1997.5001872.X |
0.337 |
|
1997 |
Ogata Y, Inoue R, Mizushima T, Kano Y, Miki T, Sekimizu K. Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU. Biochimica Et Biophysica Acta. 1353: 298-306. PMID 9349725 DOI: 10.1016/S0167-4781(97)00105-X |
0.351 |
|
1997 |
Mizushima T, Yokoyama K, Mima S, Tsuchiya T, Sekimizu K. Inhibition of thymidine transport in dnaA mutants of Escherichia coli. The Journal of Biological Chemistry. 272: 21195-200. PMID 9261126 DOI: 10.1074/Jbc.272.34.21195 |
0.328 |
|
1997 |
Mizushima T, Nishida S, Kurokawa K, Katayama T, Miki T, Sekimizu K. Negative control of DNA replication by hydrolysis of ATP bound to DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli. The Embo Journal. 16: 3724-30. PMID 9218813 DOI: 10.1093/Emboj/16.12.3724 |
0.37 |
|
1997 |
Ohtsuka Y, Mizushima T, Miki T, Sekimizu K. Transient DNA relaxation in Escherichia coli induced by nalidixic acid. Biological & Pharmaceutical Bulletin. 20: 467-70. PMID 9178922 DOI: 10.1248/Bpb.20.467 |
0.348 |
|
1997 |
Nishida S, Mizushima T, Miki T, Sekimizu K. Immotile phenotype of an Escherichia coli mutant lacking the histone-like protein HU. Fems Microbiology Letters. 150: 297-301. PMID 9170274 DOI: 10.1111/J.1574-6968.1997.Tb10384.X |
0.311 |
|
1997 |
Mizushima T, Koyanagi R, Katayama T, Miki T, Sekimizu K. Decrease in expression of the master operon of flagellin synthesis in a dnaA46 mutant of Escherichia coli. Biological & Pharmaceutical Bulletin. 20: 327-31. PMID 9145203 DOI: 10.1248/Bpb.20.327 |
0.308 |
|
1997 |
Kubota T, Katayama T, Ito Y, Mizushima T, Sekimizu K. Conformational transition of DnaA protein by ATP: structural analysis of DnaA protein, the initiator of Escherichia coli chromosome replication. Biochemical and Biophysical Research Communications. 232: 130-5. PMID 9125116 DOI: 10.1006/Bbrc.1997.6244 |
0.306 |
|
1997 |
Ohba A, Mizushima T, Katayama T, Sekimizu K. Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli. Febs Letters. 404: 125-8. PMID 9119048 DOI: 10.1016/S0014-5793(97)00108-7 |
0.323 |
|
1997 |
Mizushima T, Kataoka K, Ogata Y, Inoue R, Sekimizu K. Increase in negative supercoiling of plasmid DNA in Escherichia coli exposed to cold shock. Molecular Microbiology. 23: 381-6. PMID 9044271 DOI: 10.1046/J.1365-2958.1997.2181582.X |
0.352 |
|
1997 |
Mizushima T, Ohtsuka Y, Mori H, Miki T, Sekimizu K. Increase in synthesis and stability of sigma 32 on treatment with inhibitors of DNA gyrase in Escherichia coli. Molecular & General Genetics : Mgg. 253: 297-302. PMID 9003316 DOI: 10.1007/Pl00008596 |
0.373 |
|
1997 |
Mizushima T, Matsuo M, Sekimizu K. Induction of DnaK and GroEL heat shock proteins by fluoroquinolones in Escherichia coli. Antimicrobial Agents and Chemotherapy. 41: 193-5. PMID 8980780 DOI: 10.1128/Aac.41.1.193 |
0.351 |
|
1997 |
Matsuo M, Ohtsuka Y, Kataoka K, Mizushima T, Sekimizu K. Transient relaxation of plasmid DNA in Escherichia coli by fluoroquinolones. The Journal of Pharmacy and Pharmacology. 48: 985-7. PMID 8910869 DOI: 10.1111/J.2042-7158.1996.Tb06018.X |
0.328 |
|
1997 |
Ogata Y, Mizushima T, Kataoka K, Kita K, Miki T, Sekimizu K. DnaK heat shock protein of Escherichia coli maintains the negative supercoiling of DNA against thermal stress. The Journal of Biological Chemistry. 271: 29407-14. PMID 8910606 DOI: 10.1074/Jbc.271.46.29407 |
0.341 |
|
1997 |
Kurokawa K, Mizushima T, Miki T, Sekimizu K. Influence of the linking number of template DNA on sigma 32-dependent transcription initiation in vitro of the Escherichia coli groE gene. Biological & Pharmaceutical Bulletin. 19: 922-31. PMID 8839962 DOI: 10.1248/Bpb.19.922 |
0.33 |
|
1996 |
Mizushima T, Sasaki S, Ohishi H, Kobayashi M, Katayama T, Miki T, Maeda M, Sekimizu K. Molecular design of inhibitors of in vitro oriC DNA replication based on the potential to block the ATP binding of DnaA protein. The Journal of Biological Chemistry. 271: 25178-83. PMID 8810275 DOI: 10.1074/Jbc.271.41.25178 |
0.345 |
|
1996 |
Mizushima T, Shinpuku T, Katayama H, Kataoka K, Guo L, Miki T, Sekimizu K. Phenotypes of dnaA mutants of Escherichia coli sensitive to phenothiazine derivatives. Molecular & General Genetics : Mgg. 252: 212-5. PMID 8804395 DOI: 10.1007/S004389670024 |
0.315 |
|
1996 |
Kataoka K, Mizushima T, Ogata Y, Miki T, Sekimizu K. Heat shock-induced DNA relaxation in vitro by DNA gyrase of Escherichia coli in the presence of ATP. The Journal of Biological Chemistry. 271: 24806-10. PMID 8798753 DOI: 10.1074/Jbc.271.40.24806 |
0.319 |
|
1996 |
Mizushima T, Katayama T, Sekimizu K. Effect on DNA topology by DnaA protein, the initiation factor of chromosomal DNA replication in Escherichia coli. Biochemistry. 35: 11512-6. PMID 8784207 DOI: 10.1021/Bi953088F |
0.341 |
|
1996 |
Kaneko T, Mizushima T, Ohtsuka Y, Kurokawa K, Kataoka K, Miki T, Sekimizu K. Co-induction of DNA relaxation and synthesis of DnaK and GroEL proteins in Escherichia coli by expression of LetD (CcdB) protein, an inhibitor of DNA gyrase encoded by the F factor. Molecular & General Genetics : Mgg. 250: 593-600. PMID 8676862 DOI: 10.1007/Bf02174447 |
0.371 |
|
1996 |
Mizushima T, Koyanagi R, Suzuki E, Tomura A, Kutsukake K, Miki T, Sekimizu K. Control by phosphatidylglycerol of expression of the flhD gene in Escherichia coli. Biochimica Et Biophysica Acta. 1245: 397-401. PMID 8541318 DOI: 10.1016/0304-4165(95)00114-X |
0.306 |
|
1996 |
Kaneko T, Mizushima T, Ohtsuka Y, Kurokawa K, Kataoka K, Miki T, Sekimizu K. Co-induction of DNA relaxation and synthesis of DnaK and GroEL proteins in Molecular Genetics and Genomics. 250: 593. DOI: 10.1007/S004380050112 |
0.312 |
|
1994 |
Ogata Y, Mizushima T, Kataoka K, Miki T, Sekimizu K. Identification of DNA topoisomerases involved in immediate and transient DNA relaxation induced by heat shock in Escherichia coli. Molecular & General Genetics : Mgg. 244: 451-5. PMID 8078472 DOI: 10.1007/Bf00583895 |
0.332 |
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1994 |
Mizushima T, Ohtsuka Y, Miki T, Sekimizu K. Temperature shift-up leads to simultaneous and continuous plasmid DNA relaxation and induction of DnaK and GroEL proteins in anaerobically growing Escherichia coli cells. Fems Microbiology Letters. 121: 333-6. PMID 7926689 DOI: 10.1111/J.1574-6968.1994.Tb07122.X |
0.33 |
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