Carlos E. Crespo-Hernandez, Ph.D. - Publications

Affiliations: 
2007- Chemistry Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
ultrafast electronic spectroscopy; excited-state dynamics; DNA photochemistry; photosensitizers; photodynamic therapy; organic photochemistry
Website:
http://chemistry.case.edu/faculty/carlos-crespo-hernandez/

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sharma D, Zagore LL, Brister MM, Ye X, Crespo-Hernández CE, Licatalosi DD, Jankowsky E. The kinetic landscape of an RNA-binding protein in cells. Nature. PMID 33568810 DOI: 10.1038/s41586-021-03222-x  1
2020 Ortiz-Rodríguez LA, Reichardt C, Hoehn SJ, Jockusch S, Crespo-Hernández CE. Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct. Nature Communications. 11: 3599. PMID 32680990 DOI: 10.1038/s41467-020-17333-y  1
2020 Arpa EM, Brister MM, Hoehn SJ, Crespo-Hernández CE, Corral I. On the Origin of the Photostability of DNA and RNA Monomers: Excited State Relaxation Mechanism of the Pyrimidine Chromophore. The Journal of Physical Chemistry Letters. PMID 32501702 DOI: 10.1021/acs.jpclett.0c00935  1
2020 Brister MM, Gustavsson T, Crespo-Hernández CE. Excited State Lifetimes of Sulfur-Substituted DNA and RNA Monomers Probed Using the Femtosecond Fluorescence Up-Conversion Technique. Molecules (Basel, Switzerland). 25. PMID 32013184 DOI: 10.3390/molecules25030584  1
2019 Ashfold M, Bai S, Bradforth S, Chabera P, Cina J, Crespo-Hernández CE, das Neves Rodrigues N, Duchi M, Fleming G, Grieco C, Habershon S, Haggmark M, Hammes-Schiffer S, Hsieh ST, Kohler B, et al. Photo-protection/photo-damage in natural systems: general discussion. Faraday Discussions. PMID 31273373 DOI: 10.1039/c9fd90031d  1
2019 Ashfold M, Bender J, Bittner E, Cina J, Crespo-Hernández CE, das Neves Rodrigues N, Dawlaty J, Dill R, Dodin A, Duchi M, Estergreen L, Gate G, Gaynor J, Ginsberg N, Grieco C, et al. Photovoltaics and bio-inspired light harvesting: general discussion. Faraday Discussions. PMID 31270516 DOI: 10.1039/c9fd90028d  1
2019 Martínez-Fernández L, Arslancan S, Ivashchenko D, Crespo-Hernández CE, Corral I. Tracking the origin of photostability in purine nucleobases: the photophysics of 2-oxopurine. Physical Chemistry Chemical Physics : Pccp. PMID 31187825 DOI: 10.1039/c9cp00879a  1
2019 Brister MM, Crespo-Hernández CE. Excited-State Dynamics in the RNA Nucleotide Uridine 5'-Monophosphate Investigated Using Femtosecond Broadband Transient Absorption Spectroscopy. The Journal of Physical Chemistry Letters. 2156-2161. PMID 30995048 DOI: 10.1021/acs.jpclett.9b00492  1
2018 Farrell KM, Brister MM, Pittelkow M, Sølling TI, Crespo-Hernández CE. Heavy-Atom-Substituted Nucleobases in Photodynamic Applications: Substitution of Sulfur with Selenium in 6-Thioguanine Induces a Remarkable Increase in the Rate of Triplet Decay in 6-Selenoguanine. Journal of the American Chemical Society. PMID 30145892 DOI: 10.1021/jacs.8b07665  1
2018 Ashwood B, Pollum M, Crespo-Hernández CE. Photochemical and Photodynamical Properties of Sulfur-Substituted Nucleic Acid Bases. Photochemistry and Photobiology. PMID 29978490 DOI: 10.1111/php.12975  1
2018 Chattopadhyay A, Cogdell R, Crespo-Hernández CE, Datta A, De A, Haacke S, Hariharan M, Helliwell J, Hughes A, Improta R, Jones M, Joseph J, Karsili T, Kohler B, Krishnan R, et al. Light induced charge and energy transport in nucleic acids and proteins: general discussion. Faraday Discussions. PMID 29620133 DOI: 10.1039/c8fd90004c  1
2018 Bhat V, Cogdell R, Crespo-Hernández CE, Datta A, De A, Haacke S, Helliwell J, Improta R, Joseph J, Karsili T, Kohler B, Krishnan R, L M, Lewis F, Mandal I, et al. Photocrosslinking between nucleic acids and proteins: general discussion. Faraday Discussions. PMID 29617022 DOI: 10.1039/c8fd90005a  1
2018 Chandra A, Cogdell R, Crespo-Hernández CE, Datta A, Giussani A, Haacke S, Helliwell J, Improta R, Jayasree RS, Jones M, Karsili T, Kohler B, L M, Mandal I, Markovitsi D, et al. Light induced damage and repair in nucleic acids and proteins: general discussion. Faraday Discussions. PMID 29617016 DOI: 10.1039/c8fd90006j  1
2018 Pollum M, Lam M, Jockusch S, Crespo-Hernández CE. Dithionated Nucleobases as Effective Photodynamic Agents Against Epidermoid Carcinoma Cells. Chemmedchem. PMID 29532623 DOI: 10.1002/cmdc.201800148  1
2018 Ashwood B, Ortiz-Rodríguez LA, Crespo-Hernández CE. Photochemical relaxation pathways of S6-methylthioinosine and O6-methylguanosine in solution. Faraday Discussions. PMID 29372193 DOI: 10.1039/c7fd00193b  1
2017 Crespo-Hernández CE. Photorelaxation and Photorepair Processes in Nucleic and Amino Acid Derivatives. Molecules (Basel, Switzerland). 22. PMID 29231852 DOI: 10.3390/molecules22122203  0.01
2017 Brister MM, Piñero-Santiago LE, Morel M, Arce R, Crespo-Hernández CE. Photochemical Relaxation Pathways in Dinitropyrene Isomer Pollutants. The Journal of Physical Chemistry. A. PMID 28984454 DOI: 10.1021/acs.jpca.7b04769  1
2017 Ashwood B, Ortiz-Rodríguez LA, Crespo-Hernández CE. Excited-State Dynamics in O(6)-Methylguanosine: Impact of O(6)-Methylation on the Relaxation Mechanism of Guanine Monomers. The Journal of Physical Chemistry Letters. 4380-4385. PMID 28850232 DOI: 10.1021/acs.jpclett.7b02090  0.01
2017 Sánchez-Rodríguez JA, Mohamadzade A, Mai S, Ashwood B, Pollum M, Marquetand P, González L, Crespo-Hernández CE, Ullrich S. 2-Thiouracil intersystem crossing photodynamics studied by wavelength-dependent photoelectron and transient absorption spectroscopies. Physical Chemistry Chemical Physics : Pccp. PMID 28630971 DOI: 10.1039/c7cp02258a  1
2017 Tolbert M, Morgan CE, Pollum M, Crespo-Hernández CE, Li ML, Brewer G, Tolbert BS. HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation. Journal of Molecular Biology. PMID 28625847 DOI: 10.1016/j.jmb.2017.06.007  1
2017 Ashwood B, Jockusch S, Crespo-Hernández CE. Photochemical Reactivity of dTPT3: A Crucial Nucleobase Derivative in the Development of Semisynthetic Organisms. The Journal of Physical Chemistry Letters. 2387-2392. PMID 28488432 DOI: 10.1021/acs.jpclett.7b00926  1
2017 DiScipio RM, Santiago RY, Taylor D, Crespo-Hernández CE. Electronic relaxation pathways of the biologically relevant pterin chromophore. Physical Chemistry Chemical Physics : Pccp. PMID 28480921 DOI: 10.1039/c7cp01574g  0.64
2017 Mai S, Ashwood B, Marquetand P, Crespo-Hernández CE, Gonzalez L. Solvatochromic Effects on the Absorption Spectrum of 2-Thiocytosine. The Journal of Physical Chemistry. B. PMID 28452483 DOI: 10.1021/acs.jpcb.7b02715  1
2017 Ashwood B, Jockusch S, Crespo-Hernández CE. Excited-State Dynamics of the Thiopurine Prodrug 6-Thioguanine: Can N9-Glycosylation Affect Its Phototoxic Activity? Molecules (Basel, Switzerland). 22. PMID 28264514 DOI: 10.3390/molecules22030379  1
2016 Brister MM, Piñero-Santiago LE, Morel M, Arce R, Crespo-Hernández CE. The Photochemical Branching Ratio in 1,6-Dinitropyrene Depends on the Excitation Energy. The Journal of Physical Chemistry Letters. 7: 5086-5092. PMID 27973879 DOI: 10.1021/acs.jpclett.6b02549  1
2016 Martínez-Fernández L, Granucci G, Pollum M, Crespo-Hernández CE, Persico M, Corral I. Decoding the Molecular Basis for the Population Mechanism of the Triplet Phototoxic Precursors in UVA Light-Activated Pyrimidine Anticancer Drugs. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27911037 DOI: 10.1002/chem.201604543  1
2016 Ashwood B, Pollum M, Crespo-Hernández CE. Can a Six-Letter Alphabet Increase the Likelihood of Photochemical Assault to the Genetic Code? Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27723147 DOI: 10.1002/chem.201602160  1
2016 Mai S, Pollum M, Martínez-Fernández L, Dunn N, Marquetand P, Corral I, Crespo-Hernández CE, González L. The origin of efficient triplet state population in sulfur-substituted nucleobases. Nature Communications. 7: 13077. PMID 27703148 DOI: 10.1038/ncomms13077  1
2016 Pollum M, Ashwood B, Jockusch S, Lam M, Crespo-Hernández CE. Unintended Consequences of Expanding the Genetic Alphabet. Journal of the American Chemical Society. PMID 27564795 DOI: 10.1021/jacs.6b06822  1
2016 Brister MM, Pollum M, Crespo-Hernández CE. Correction: Photochemical etiology of promising ancestors of the RNA nucleobases. Physical Chemistry Chemical Physics : Pccp. 18: 22731. PMID 27453196 DOI: 10.1039/c6cp90188c  1
2016 Yu H, Sanchez-Rodriguez JA, Pollum M, Crespo-Hernández CE, Mai S, Marquetand P, González L, Ullrich S. Internal conversion and intersystem crossing pathways in UV excited, isolated uracils and their implications in prebiotic chemistry. Physical Chemistry Chemical Physics : Pccp. PMID 27189184 DOI: 10.1039/c6cp01790h  1
2016 Brister MM, Pollum M, Crespo-Hernández CE. Photochemical etiology of promising ancestors of the RNA nucleobases. Physical Chemistry Chemical Physics : Pccp. 18: 20097-103. PMID 26898746 DOI: 10.1039/c6cp00639f  1
2016 Pollum M, Ortiz-Rodríguez LA, Jockusch S, Crespo-Hernández CE. The Triplet State of 6-Thio-2'-deoxyguanosine: Intrinsic Properties and Reactivity Toward Molecular Oxygen. Photochemistry and Photobiology. PMID 26757207 DOI: 10.1111/php.12563  1
2015 Brister MM, Crespo-Hernández CE. Direct Observation of Triplet-State Population Dynamics in the RNA Uracil Derivative 1-Cyclohexyluracil. The Journal of Physical Chemistry Letters. 6: 4404-9. PMID 26538051 DOI: 10.1021/acs.jpclett.5b01901  1
2015 Pollum M, Jockusch S, Crespo-Hernández CE. Increase in the photoreactivity of uracil derivatives by doubling thionation. Physical Chemistry Chemical Physics : Pccp. 17: 27851-61. PMID 26439833 DOI: 10.1039/c5cp04822b  1
2015 Crespo-Hernández CE, Martínez-Fernández L, Rauer C, Reichardt C, Mai S, Pollum M, Marquetand P, González L, Corral I. Electronic and structural elements that regulate the excited-state dynamics in purine nucleobase derivatives. Journal of the American Chemical Society. 137: 4368-81. PMID 25763596 DOI: 10.1021/ja512536c  1
2015 Pollum M, Martínez-Fernández L, Crespo-Hernández CE. Photochemistry of nucleic acid bases and their thio- and aza-analogues in solution. Topics in Current Chemistry. 355: 245-327. PMID 25238718 DOI: 10.1007/128_2014_554  1
2014 Pollum M, Jockusch S, Crespo-Hernández CE. 2,4-Dithiothymine as a potent UVA chemotherapeutic agent. Journal of the American Chemical Society. 136: 17930-3. PMID 25506742 DOI: 10.1021/ja510611j  1
2014 Pollum M, Crespo-Hernández CE. Communication: the dark singlet state as a doorway state in the ultrafast and efficient intersystem crossing dynamics in 2-thiothymine and 2-thiouracil. The Journal of Chemical Physics. 140: 071101. PMID 24559331 DOI: 10.1063/1.4866447  1
2013 Vogt RA, Crespo-Hernández CE. Conformational control in the population of the triplet state and photoreactivity of nitronaphthalene derivatives. The Journal of Physical Chemistry. A. 117: 14100-8. PMID 24283295 DOI: 10.1021/jp4101587  1
2013 Vogt RA, Reichardt C, Crespo-Hernández CE. Excited-state dynamics in nitro-naphthalene derivatives: intersystem crossing to the triplet manifold in hundreds of femtoseconds. The Journal of Physical Chemistry. A. 117: 6580-8. PMID 23845162 DOI: 10.1021/jp405656n  1
2013 Reichardt C, Wen C, Vogt RA, Crespo-Hernández CE. Role of intersystem crossing in the fluorescence quenching of 2-aminopurine 2'-deoxyriboside in solution. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 12: 1341-50. PMID 23529277 DOI: 10.1039/c3pp25437b  1
2013 Fujiwara T, Reichardt C, Vogt RA, Crespo-Hernández CE, Zgierski MZ, Lim EC. Electronic spectra and excited-state dynamics of 4-fluoro-N,N- dimethylaniline Chemical Physics Letters. 586: 70-75. DOI: 10.1016/j.cplett.2013.09.028  1
2012 Vogt RA, Gray TG, Crespo-Hernández CE. Subpicosecond intersystem crossing in mono- and di(organophosphine)gold(I) naphthalene derivatives in solution. Journal of the American Chemical Society. 134: 14808-17. PMID 22909171 DOI: 10.1021/ja303592q  1
2012 Isayev O, Crespo-Hernández CE, Gorb L, Hill FC, Leszczynski J. In silico structure-function analysis of E. cloacae nitroreductase. Proteins. 80: 2728-41. PMID 22865652 DOI: 10.1002/prot.24157  1
2011 Santos-Pérez J, Crespo-Hernández CE, Reichardt C, Cabrera CR, Feliciano-Ramos I, Arroyo-Ramírez L, Meador MA. Synthesis, optical characterization, and electrochemical properties of isomeric tetraphenylbenzodifurans containing electron acceptor groups. The Journal of Physical Chemistry. A. 115: 4157-68. PMID 21473598 DOI: 10.1021/jp111174p  1
2011 Reichardt C, Guo C, Crespo-Hernández CE. Excited-state dynamics in 6-thioguanosine from the femtosecond to microsecond time scale. The Journal of Physical Chemistry. B. 115: 3263-70. PMID 21384813 DOI: 10.1021/jp112018u  1
2011 Dodson LG, Vogt RA, Marks J, Reichardt C, Crespo-Hernández CE. Photophysical and photochemical properties of the pharmaceutical compound salbutamol in aqueous solutions. Chemosphere. 83: 1513-23. PMID 21316733 DOI: 10.1016/j.chemosphere.2011.01.048  1
2011 Díaz-Espinosa Y, Crespo-Hernández CE, Alegría AE, García C, Arce R. Quenching enhancement of the singlet excited state of pheophorbide-a by DNA in the presence of the quinone carboquone. Photochemistry and Photobiology. 87: 275-83. PMID 21138440 DOI: 10.1111/j.1751-1097.2010.00869.x  1
2010 Reichardt C, Crespo-Hernández CE. Ultrafast spin crossover in 4-thiothymidine in an ionic liquid. Chemical Communications (Cambridge, England). 46: 5963-5. PMID 20617255 DOI: 10.1039/c0cc01181a  1
2010 Reichardt C, Crespo-Hernaíndez CE. Room-temperature phosphorescence of the DNA monomer analogue 4-thiothymidine in aqueous solutions after UVA excitation Journal of Physical Chemistry Letters. 1: 2239-2243. DOI: 10.1021/jz100729w  0.88
2009 Reichardt C, Vogt RA, Crespo-Hernández CE. On the origin of ultrafast nonradiative transitions in nitro-polycyclic aromatic hydrocarbons: Excited-state dynamics in 1-nitronaphthalene. The Journal of Chemical Physics. 131: 224518. PMID 20001068 DOI: 10.1063/1.3272536  1
2009 de La Harpe K, Crespo-Hernández CE, Kohler B. Deuterium isotope effect on excited-state dynamics in an alternating GC oligonucleotide. Journal of the American Chemical Society. 131: 17557-9. PMID 19950991 DOI: 10.1021/ja9076364  1
2009 de la Harpe K, Crespo-Hernández CE, Kohler B. The excited-state lifetimes in a G x C DNA duplex are nearly independent of helix conformation and base-pairing motif. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 10: 1421-5. PMID 19301308 DOI: 10.1002/cphc.200900004  0.88
2009 Middleton CT, de La Harpe K, Su C, Law YK, Crespo-Hernández CE, Kohler B. DNA excited-state dynamics: from single bases to the double helix. Annual Review of Physical Chemistry. 60: 217-39. PMID 19012538 DOI: 10.1146/annurev.physchem.59.032607.093719  1
2008 Takaya T, Su C, de La Harpe K, Crespo-Hernández CE, Kohler B. UV excitation of single DNA and RNA strands produces high yields of exciplex states between two stacked bases. Proceedings of the National Academy of Sciences of the United States of America. 105: 10285-90. PMID 18647840 DOI: 10.1073/pnas.0802079105  0.56
2008 Crespo-Hernández CE, de la Harpe K, Kohler B. Ground-state recovery following UV excitation is much slower in G x C-DNA duplexes and hairpins than in mononucleotides. Journal of the American Chemical Society. 130: 10844-5. PMID 18646753 DOI: 10.1021/ja802183s  1
2008 Crespo-Hernández CE, Burdzinski G, Arce R. Environmental photochemistry of nitro-PAHs: direct observation of ultrafast intersystem crossing in 1-nitropyrene. The Journal of Physical Chemistry. A. 112: 6313-9. PMID 18572893 DOI: 10.1021/jp803847q  1
2008 Close DM, Crespo-Hernández CE, Gorb L, Leszczynski J. Theoretical elucidation of conflicting experimental data on vertical ionization potentials of microhydrated thymine. The Journal of Physical Chemistry. A. 112: 4405-9. PMID 18402430 DOI: 10.1021/jp711157b  1
2008 Law YK, Azadi J, Crespo-Hernández CE, Olmon E, Kohler B. Predicting thymine dimerization yields from molecular dynamics simulations. Biophysical Journal. 94: 3590-600. PMID 18192364 DOI: 10.1529/biophysj.107.118612  1
2007 Crespo-Hernandez CE, Close DM, Gorb L, Leszczynski J. Determination of redox potentials for the Watson-Crick base pairs, DNA nucleosides, and relevant nucleoside analogues. The Journal of Physical Chemistry. B. 111: 5386-95. PMID 17447808 DOI: 10.1021/jp0684224  1
2007 Schreier WJ, Schrader TE, Koller FO, Gilch P, Crespo-Hernández CE, Swaminathan VN, Carell T, Zinth W, Kohler B. Thymine dimerization in DNA is an ultrafast photoreaction. Science (New York, N.Y.). 315: 625-9. PMID 17272716 DOI: 10.1126/science.1135428  1
2007 Hare PM, Crespo-Hernández CE, Kohler B. Internal conversion to the electronic ground state occurs via two distinct pathways for pyrimidine bases in aqueous solution. Proceedings of the National Academy of Sciences of the United States of America. 104: 435-40. PMID 17197421 DOI: 10.1073/pnas.0608055104  1
2006 Hare PM, Crespo-Hernández CE, Kohler B. Solvent-dependent photophysics of 1-cyclohexyluracil: ultrafast branching in the initial bright state leads nonradiatively to the electronic ground state and a long-lived 1npi* state. The Journal of Physical Chemistry. B. 110: 18641-50. PMID 16970494 DOI: 10.1021/jp064714t  1
2006 Colón L, Crespo-Hernández CE, Oyola R, García C, Arce R. Role of sequence and conformation on the photochemistry and the photophysics of A-T DNA dimers: an experimental and computational approach. The Journal of Physical Chemistry. B. 110: 15589-96. PMID 16884283 DOI: 10.1021/jp060236a  1
2006 Close DM, Crespo-Hernandez CE, Gorb L, Leszczynski J. Influence of microhydration on the ionization energy thresholds of thymine: comparisons of theoretical calculations with experimental values. The Journal of Physical Chemistry. A. 110: 7485-90. PMID 16759139 DOI: 10.1021/jp061064k  1
2005 Close DM, Crespo-Hernández CE, Gorb L, Leszczynski J. The influence of microhydration on the ionization energy thresholds of uracil and thymine. The Journal of Physical Chemistry. A. 109: 9279-83. PMID 16833269 DOI: 10.1021/jp053235b  1
2005 Crespo-Hernández CE, Cohen B, Kohler B. Base stacking controls excited-state dynamics in A.T DNA. Nature. 436: 1141-4. PMID 16121177 DOI: 10.1038/nature03933  1
2004 Cohen B, Crespo-Hernández CE, Kohler B. Strickler-Berg analysis of excited singlet state dynamics in DNA and RNA nucleosides. Faraday Discussions. 127: 137-47. PMID 15471343  1
2004 Crespo-Hernández CE, Cohen B, Hare PM, Kohler B. Ultrafast excited-state dynamics in nucleic acids. Chemical Reviews. 104: 1977-2019. PMID 15080719 DOI: 10.1021/cr0206770  1
2004 Crespo-Hernández CE, Arce R. Formamidopyrimidines as major products in the low- and high-intensity UV irradiation of guanine derivatives. Journal of Photochemistry and Photobiology. B, Biology. 73: 167-75. PMID 14975405 DOI: 10.1016/j.jphotobiol.2003.11.006  1
2002 Crespo-Hernández CE, Arce R. Photoionization of DNA and RNA bases, nucleosides and nucleotides through a combination of one- and two-photon pathways upon 266 nm nanosecond laser excitation. Photochemistry and Photobiology. 76: 259-67. PMID 12403446  1
2000 Crespo-Hernández CE, Arce R. Mechanism of formation of guanine as one of the major products in the 254 nm photolysis of guanine derivatives: concentration and pH effects. Photochemistry and Photobiology. 71: 544-50. PMID 10818784  1
2000 Crespo-Hernández CE, Flores S, Torres C, Negrón-Encarnación I, Arce R. Photochemical and photophysical studies of guanine derivatives: intermediates contributing to its photodestruction mechanism in aqueous solution and the participation of the electron adduct. Photochemistry and Photobiology. 71: 534-43. PMID 10818783  1
2000 Reyes CA, Medina M, Crespo-Hernandez C, Cedeno MZ, Arce R, Rosario O, Steffenson DM, Ivanov IN, Sigman ME, Dabestani R. Photochemistry of pyrene on unactivated and activated silica surfaces Environmental Science and Technology. 34: 415-421. DOI: 10.1021/es9905391  1
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