cached image

Clifford P. Brangwynne - Publications

Affiliations: 
Chemical and Biological Engineering Princeton University, Princeton, NJ 
Area:
self-assembly of biological materials
Website:
http://www.princeton.edu/cbe/people/faculty/brangwynne/

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Riback JA, Eeftens JM, Lee DSW, Quinodoz SA, Donlic A, Orlovsky N, Wiesner L, Beckers L, Becker LA, Strom AR, Rana U, Tolbert M, Purse BW, Kleiner R, Kriwacki R, ... Brangwynne CP, et al. Viscoelasticity and advective flow of RNA underlies nucleolar form and function. Molecular Cell. 83: 3095-3107.e9. PMID 37683610 DOI: 10.1016/j.molcel.2023.08.006  0.715
2023 Lee DSW, Choi CH, Sanders DW, Beckers L, Riback JA, Brangwynne CP, Wingreen NS. Size distributions of intracellular condensates reflect competition between coalescence and nucleation. Nature Physics. 19: 586-596. PMID 37073403 DOI: 10.1038/s41567-022-01917-0  0.687
2022 Lee DSW, Strom AR, Brangwynne CP. The mechanobiology of nuclear phase separation. Apl Bioengineering. 6: 021503. PMID 35540725 DOI: 10.1063/5.0083286  0.355
2021 Eeftens JM, Kapoor M, Michieletto D, Brangwynne CP. Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction. Nature Communications. 12: 5888. PMID 34620850 DOI: 10.1038/s41467-021-26147-5  0.302
2021 Rana U, Brangwynne CP, Panagiotopoulos AZ. Phase separation vs aggregation behavior for model disordered proteins. The Journal of Chemical Physics. 155: 125101. PMID 34598580 DOI: 10.1063/5.0060046  0.32
2021 Shimobayashi SF, Ronceray P, Sanders DW, Haataja MP, Brangwynne CP. Nucleation landscape of biomolecular condensates. Nature. PMID 34552246 DOI: 10.1038/s41586-021-03905-5  0.341
2021 Zhang Y, Lee DSW, Meir Y, Brangwynne CP, Wingreen NS. Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. Physical Review Letters. 126: 258102. PMID 34241518 DOI: 10.1103/PhysRevLett.126.258102  0.359
2020 Wei MT, Chang YC, Shimobayashi SF, Shin Y, Strom AR, Brangwynne CP. Nucleated transcriptional condensates amplify gene expression. Nature Cell Biology. PMID 32929202 DOI: 10.1038/S41556-020-00578-6  0.746
2020 Lafontaine DLJ, Riback JA, Bascetin R, Brangwynne CP. The nucleolus as a multiphase liquid condensate. Nature Reviews. Molecular Cell Biology. PMID 32873929 DOI: 10.1038/S41580-020-0272-6  0.74
2020 Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei MT, Kriwacki RW, Brangwynne CP. Composition-dependent thermodynamics of intracellular phase separation. Nature. 581: 209-214. PMID 32405004 DOI: 10.1038/S41586-020-2256-2  0.755
2020 Sanders DW, Kedersha N, Lee DSW, Strom AR, Drake V, Riback JA, Bracha D, Eeftens JM, Iwanicki A, Wang A, Wei MT, Whitney G, Lyons SM, Anderson P, Jacobs WM, ... ... Brangwynne CP, et al. Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization. Cell. 181: 306-324.e28. PMID 32302570 DOI: 10.1016/J.Cell.2020.03.050  0.736
2020 Statt A, Casademunt H, Brangwynne CP, Panagiotopoulos AZ. Model for disordered proteins with strongly sequence-dependent liquid phase behavior. The Journal of Chemical Physics. 152: 075101. PMID 32087632 DOI: 10.1063/1.5141095  0.446
2020 Riback JA, Brangwynne CP. Can phase separation buffer cellular noise? Science (New York, N.Y.). 367: 364-365. PMID 31974233 DOI: 10.1126/Science.Aba0446  0.7
2019 Bracha D, Walls MT, Brangwynne CP. Probing and engineering liquid-phase organelles. Nature Biotechnology. 37: 1435-1445. PMID 31792412 DOI: 10.1038/S41587-019-0341-6  0.427
2019 Strom AR, Brangwynne CP. The liquid nucleome - phase transitions in the nucleus at a glance. Journal of Cell Science. 132. PMID 31754043 DOI: 10.1242/Jcs.235093  0.481
2019 Taylor NO, Wei MT, Stone HA, Brangwynne CP. Quantifying Dynamics in Phase-Separated Condensates Using Fluorescence Recovery after Photobleaching. Biophysical Journal. PMID 31540706 DOI: 10.1016/J.Bpj.2019.08.030  0.432
2019 Zhu L, Richardson TM, Wacheul L, Wei MT, Feric M, Whitney G, Lafontaine DLJ, Brangwynne CP. Controlling the material properties and rRNA processing function of the nucleolus using light. Proceedings of the National Academy of Sciences of the United States of America. PMID 31399547 DOI: 10.1073/Pnas.1903870116  0.369
2019 Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL. Phase separation in biology and disease-a symposium report. Annals of the New York Academy of Sciences. PMID 31199001 DOI: 10.1111/Nyas.14126  0.442
2019 Shin Y, Chang YC, Lee DSW, Berry J, Sanders DW, Ronceray P, Wingreen NS, Haataja M, Brangwynne CP. Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell. 176: 1518. PMID 30849377 DOI: 10.1016/J.Cell.2019.02.025  0.72
2019 Bracha D, Walls MT, Wei MT, Zhu L, Kurian M, Avalos JL, Toettcher JE, Brangwynne CP. Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds. Cell. 176: 407. PMID 30633909 DOI: 10.1016/J.Cell.2018.12.026  0.369
2019 Wei M(, Brangwynne CP. Sequence Determination of Liquid-Liquid Phase-Separated Assemblies of Engineered Disordered Proteins in Living Cells Biophysical Journal. 116: 454a. DOI: 10.1016/J.Bpj.2018.11.2449  0.412
2018 Shin Y, Chang YC, Lee DSW, Berry J, Sanders DW, Ronceray P, Wingreen NS, Haataja M, Brangwynne CP. Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell. 175: 1481-1491.e13. PMID 30500535 DOI: 10.1016/J.Cell.2018.10.057  0.754
2018 Bracha D, Walls MT, Wei MT, Zhu L, Kurian M, Avalos JL, Toettcher JE, Brangwynne CP. Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds. Cell. 175: 1467-1480.e13. PMID 30500534 DOI: 10.1016/J.Cell.2018.10.048  0.462
2018 Dine E, Gil AA, Uribe G, Brangwynne CP, Toettcher JE. Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. Cell Systems. PMID 29859829 DOI: 10.1016/J.Cels.2018.05.002  0.376
2018 Berry J, Brangwynne C, Haataja MP. Physical Principles of Intracellular Organization via Active and Passive Phase Transitions. Reports On Progress in Physics. Physical Society (Great Britain). PMID 29313527 DOI: 10.1088/1361-6633/Aaa61E  0.431
2017 Wei MT, Elbaum-Garfinkle S, Holehouse AS, Chen CC, Feric M, Arnold CB, Priestley RD, Pappu RV, Brangwynne CP. Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles. Nature Chemistry. 9: 1118-1125. PMID 29064502 DOI: 10.1038/Nchem.2803  0.443
2017 Shin Y, Brangwynne CP. Liquid phase condensation in cell physiology and disease. Science (New York, N.Y.). 357. PMID 28935776 DOI: 10.1126/Science.Aaf4382  0.772
2017 Sanders DW, Brangwynne CP. Neurodegenerative disease: RNA repeats put a freeze on cells. Nature. PMID 28562583 DOI: 10.1038/Nature22503  0.345
2016 Shin Y, Berry J, Pannucci N, Haataja MP, Toettcher JE, Brangwynne CP. Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell. PMID 28041848 DOI: 10.1016/J.Cell.2016.11.054  0.759
2016 Taylor N, Elbaum-Garfinkle S, Vaidya N, Zhang H, Stone HA, Brangwynne CP. Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics. Soft Matter. PMID 27791212 DOI: 10.1039/C6Sm01087C  0.487
2016 Uppaluri S, Weber SC, Brangwynne CP. Hierarchical Size Scaling during Multicellular Growth and Development. Cell Reports. 17: 345-352. PMID 27705784 DOI: 10.1016/J.Celrep.2016.09.007  0.314
2016 Brangwynne CP, Marko JF. Cell division: A sticky problem for chromosomes. Nature. PMID 27362225 DOI: 10.1038/Nature18904  0.308
2016 Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP. Coexisting Liquid Phases Underlie Nucleolar Subcompartments. Cell. PMID 27212236 DOI: 10.1016/J.Cell.2016.04.047  0.471
2016 Elbaum-Garfinkle S, Taylor N, Brangwynne CP. From Physiological Fluids to Pathological Gels: Disordered Proteins at the Nexus of Liquid Phase Separation and Neurodegenerative Disease Biophysical Journal. 110: 38a. DOI: 10.1016/J.Bpj.2015.11.272  0.406
2015 Elbaum-Garfinkle S, Brangwynne CP. Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration. Developmental Cell. 35: 531-2. PMID 26651288 DOI: 10.1016/J.Devcel.2015.11.014  0.376
2015 Feric M, Broedersz CP, Brangwynne CP. Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep. Scientific Reports. 5: 16607. PMID 26577186 DOI: 10.1038/Srep16607  0.366
2015 Zhang H, Elbaum-Garfinkle S, Langdon EM, Taylor N, Occhipinti P, Bridges AA, Brangwynne CP, Gladfelter AS. RNA Controls PolyQ Protein Phase Transitions. Molecular Cell. 60: 220-30. PMID 26474065 DOI: 10.1016/J.Molcel.2015.09.017  0.443
2015 Bosse JB, Hogue IB, Feric M, Thiberge SY, Sodeik B, Brangwynne CP, Enquist LW. Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion. Proceedings of the National Academy of Sciences of the United States of America. 112: E5725-33. PMID 26438852 DOI: 10.1073/Pnas.1513876112  0.3
2015 Berry J, Weber SC, Vaidya N, Haataja M, Brangwynne CP. RNA transcription modulates phase transition-driven nuclear body assembly. Proceedings of the National Academy of Sciences of the United States of America. 112: E5237-45. PMID 26351690 DOI: 10.1073/Pnas.1509317112  0.504
2015 Elbaum-Garfinkle S, Kim Y, Szczepaniak K, Chen CC, Eckmann CR, Myong S, Brangwynne CP. The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics. Proceedings of the National Academy of Sciences of the United States of America. 112: 7189-94. PMID 26015579 DOI: 10.1073/Pnas.1504822112  0.458
2015 Zhu L, Brangwynne CP. Nuclear bodies: the emerging biophysics of nucleoplasmic phases. Current Opinion in Cell Biology. 34: 23-30. PMID 25942753 DOI: 10.1016/J.Ceb.2015.04.003  0.42
2015 Gilpin W, Uppaluri S, Brangwynne CP. Worms under Pressure: Bulk Mechanical Properties of C. elegans Are Independent of the Cuticle. Biophysical Journal. 108: 1887-98. PMID 25902429 DOI: 10.1016/J.Bpj.2015.03.020  0.314
2015 Weber SC, Brangwynne CP. Inverse size scaling of the nucleolus by a concentration-dependent phase transition. Current Biology : Cb. 25: 641-6. PMID 25702583 DOI: 10.1016/J.Cub.2015.01.012  0.355
2015 Brangwynne CP, Tompa P, Pappu RV. Polymer physics of intracellular phase transitions Nature Physics. 11: 899-904. DOI: 10.1038/Nphys3532  0.444
2015 Elbaum S, Kim Y, Myong S, Brangwynne C. Assembly and Dynamics of Liquid Phase Protein Droplets Comprised of the DEAD-Box RNA Helicase, LAF-1 Biophysical Journal. 108: 230a-231a. DOI: 10.1016/J.Bpj.2014.11.1273  0.511
2014 Kim Y, Eckmann C, Brangwynne CP, Myong S. DEAD Box Helicases in Rnp Granule Biophysical Journal. 106: 71a. DOI: 10.1016/J.Bpj.2013.11.471  0.356
2013 Brangwynne CP. Phase transitions and size scaling of membrane-less organelles. The Journal of Cell Biology. 203: 875-81. PMID 24368804 DOI: 10.1083/Jcb.201308087  0.407
2013 Lee CF, Brangwynne CP, Gharakhani J, Hyman AA, Jülicher F. Spatial organization of the cell cytoplasm by position-dependent phase separation. Physical Review Letters. 111: 088101. PMID 24010479 DOI: 10.1103/Physrevlett.111.088101  0.619
2013 Feric M, Brangwynne CP. A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells. Nature Cell Biology. 15: 1253-9. PMID 23995731 DOI: 10.1038/Ncb2830  0.364
2013 Broedersz CP, Brangwynne CP. Nuclear mechanics: lamin webs and pathological blebs. Nucleus (Austin, Tex.). 4: 156-9. PMID 23697996 DOI: 10.4161/Nucl.25019  0.315
2013 Brangwynne CP, Johnson TL. The micro and macro of RNA function. Molecular Biology of the Cell. 24: 679. PMID 23486403 DOI: 10.1091/Mbc.E13-01-0012  0.361
2013 Lee CF, Brangwynne CP, Gharakhani J, Hyman AA, Jülicher F. Erratum: Spatial Organization of the Cell Cytoplasm by Position-Dependent Phase Separation [Phys. Rev. Lett. 111, 088101 (2013)] Physical Review Letters. 111. DOI: 10.1103/Physrevlett.111.269902  0.558
2013 Brangwynne CP, Feric M. Gravitational Stabilization of an RNA/Protein Droplet Emulsion by a Nuclear Actin Network Biophysical Journal. 104: 186a. DOI: 10.1016/J.Bpj.2012.11.1048  0.406
2012 Weber SC, Brangwynne CP. Getting RNA and protein in phase. Cell. 149: 1188-91. PMID 22682242 DOI: 10.1016/J.Cell.2012.05.022  0.455
2011 Hyman AA, Brangwynne CP. Beyond stereospecificity: liquids and mesoscale organization of cytoplasm. Developmental Cell. 21: 14-6. PMID 21763600 DOI: 10.1016/J.Devcel.2011.06.013  0.619
2011 Brangwynne CP, Mitchison TJ, Hyman AA. Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences of the United States of America. 108: 4334-9. PMID 21368180 DOI: 10.1073/Pnas.1017150108  0.668
2011 Brangwynne CP. Soft active aggregates: Mechanics, dynamics and self-assembly of liquid-like intracellular protein bodies Soft Matter. 7: 3052-3059. DOI: 10.1039/C0Sm00981D  0.42
2010 Greenan G, Brangwynne CP, Jaensch S, Gharakhani J, Jülicher F, Hyman AA. Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos. Current Biology : Cb. 20: 353-8. PMID 20137951 DOI: 10.1016/J.Cub.2009.12.050  0.528
2009 Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA. Intracellular transport by active diffusion. Trends in Cell Biology. 19: 423-7. PMID 19699642 DOI: 10.1016/J.Tcb.2009.04.004  0.457
2009 Brangwynne CP, Eckmann CR, Courson DS, Rybarska A, Hoege C, Gharakhani J, Jülicher F, Hyman AA. Germline P granules are liquid droplets that localize by controlled dissolution/condensation. Science (New York, N.Y.). 324: 1729-32. PMID 19460965 DOI: 10.1126/Science.1172046  0.586
2008 Gardel ML, Kasza KE, Brangwynne CP, Liu J, Weitz DA. Chapter 19: Mechanical response of cytoskeletal networks. Methods in Cell Biology. 89: 487-519. PMID 19118688 DOI: 10.1016/S0091-679X(08)00619-5  0.749
2008 Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA. Cytoplasmic diffusion: molecular motors mix it up. The Journal of Cell Biology. 183: 583-7. PMID 19001127 DOI: 10.1083/Jcb.200806149  0.413
2008 Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. Journal of Cell Science. 121: 2293-300. PMID 18559893 DOI: 10.1242/Jcs.024018  0.486
2008 Brangwynne CP, Koenderink GH, Mackintosh FC, Weitz DA. Nonequilibrium microtubule fluctuations in a model cytoskeleton. Physical Review Letters. 100: 118104. PMID 18517833 DOI: 10.1103/Physrevlett.100.118104  0.484
2007 Brangwynne CP, MacKintosh FC, Weitz DA. Force fluctuations and polymerization dynamics of intracellular microtubules. Proceedings of the National Academy of Sciences of the United States of America. 104: 16128-33. PMID 17911265 DOI: 10.1073/Pnas.0703094104  0.501
2007 Brangwynne CP, Koenderink GH, Barry E, Dogic Z, MacKintosh FC, Weitz DA. Bending dynamics of fluctuating biopolymers probed by automated high-resolution filament tracking. Biophysical Journal. 93: 346-59. PMID 17416612 DOI: 10.1529/Biophysj.106.096966  0.478
2007 Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ. A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2064-73. PMID 17341683 DOI: 10.1096/Fj.06-7510Com  0.449
2007 Kasza KE, Rowat AC, Liu J, Angelini TE, Brangwynne CP, Koenderink GH, Weitz DA. The cell as a material. Current Opinion in Cell Biology. 19: 101-7. PMID 17174543 DOI: 10.1016/J.Ceb.2006.12.002  0.724
2006 Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA. Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. The Journal of Cell Biology. 173: 733-41. PMID 16754957 DOI: 10.1083/Jcb.200601060  0.467
2005 Huang S, Brangwynne CP, Parker KK, Ingber DE. Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence. Cell Motility and the Cytoskeleton. 61: 201-13. PMID 15986404 DOI: 10.1002/Cm.20077  0.347
2005 Kaufman LJ, Brangwynne CP, Kasza KE, Filippidi E, Gordon VD, Deisboeck TS, Weitz DA. Glioma expansion in collagen I matrices: analyzing collagen concentration-dependent growth and motility patterns. Biophysical Journal. 89: 635-50. PMID 15849239 DOI: 10.1529/Biophysj.105.061994  0.727
1999 Chen CS, Brangwynne C, Ingber DE. Pictures in cell biology: squaring up to the cell-shape debate. Trends in Cell Biology. 9: 283. PMID 10438233 DOI: 10.1016/S0962-8924(99)01551-2  0.352
Show low-probability matches.