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Year Citation  Score
2023 Robinson HL, Moerke MJ, Banks ML, Negus SS. Effects of naltrexone on amphetamine choice in rhesus monkeys and rats. Experimental and Clinical Psychopharmacology. PMID 37184942 DOI: 10.1037/pha0000655  0.453
2023 Baird TR, Karin KN, Marsh SA, Carroll FI, Medina-Contreras JML, Negus SS, Eltit JM. Rate of onset of dopamine transporter inhibitors assessed with intracranial self-stimulation and in vivo dopamine photometry in rats. Psychopharmacology. PMID 36802016 DOI: 10.1007/s00213-023-06340-8  0.36
2022 Li M, Stevens DL, Arriaga M, Townsend EA, Mendez RE, Blajkevch NA, Selley DE, Banks ML, Negus SS, Dewey WL, Zhang Y. Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure-Activity Relationship Study on Nalfurafine Analogues. Acs Chemical Neuroscience. PMID 36449691 DOI: 10.1021/acschemneuro.2c00526  0.306
2022 Marcus MM, Negus SS, Banks ML. Effects of environmental manipulations on cocaine-vs-social choice in male and female rats. Pharmacology, Biochemistry, and Behavior. 220: 173462. PMID 36084838 DOI: 10.1016/j.pbb.2022.173462  0.379
2022 Townsend EA, Blough BE, Epstein DH, Negus SS, Shaham Y, Banks ML. Effect of TRV130 and methadone on fentanyl-vs.-food choice and somatic withdrawal signs in opioid-dependent and post-opioid-dependent rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35906489 DOI: 10.1038/s41386-022-01393-3  0.369
2022 Santos EJ, Banks ML, Negus SS. Role of Efficacy as a Determinant of Locomotor Activation by Mu Opioid Receptor Ligands in Female and Male Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 35489781 DOI: 10.1124/jpet.121.001045  0.303
2022 Baird TR, Akbarali HI, Dewey WL, Elder H, Kang M, Marsh SA, Peace MR, Poklis JL, Santos EJ, Negus SS. Opioid-like adverse effects of tianeptine in male rats and mice. Psychopharmacology. 239: 2187-2199. PMID 35211768 DOI: 10.1007/s00213-022-06093-w  0.358
2022 Banks ML, Hutsell BA, Negus SS. Contextual extinction of drug-associated discriminative stimuli fails to attenuate drug-vs-food choice in rhesus monkeys. Journal of the Experimental Analysis of Behavior. PMID 34990015 DOI: 10.1002/jeab.734  0.397
2021 Moerke MJ, Negus SS, Banks ML. Lack of effect of the nociceptin opioid peptide agonist Ro 64-6198 on pain-depressed behavior and heroin choice in rats. Drug and Alcohol Dependence. 231: 109255. PMID 34998256 DOI: 10.1016/j.drugalcdep.2021.109255  0.33
2021 Baird TR, Davies RA, Glennon RA, Peace MR, Negus SS. A Strategy to Prioritize Emerging Drugs of Abuse for Analysis: Abuse Liability Testing Using Intracranial Self-Stimulation (ICSS) in Rats and Validation with α-Pyrrolidinohexanophenone (α-PHP). Emerging Trends in Drugs, Addictions, and Health. 1. PMID 34296204 DOI: 10.1016/j.etdah.2021.100004  0.396
2021 Cornelissen JC, Blough BE, Bohn LM, Negus SS, Banks ML. Some effects of putative G-protein biased mu-opioid receptor agonists in male rhesus monkeys. Behavioural Pharmacology. PMID 33883450 DOI: 10.1097/FBP.0000000000000634  0.327
2021 Moerke MJ, Negus SS. Temporal parameters of enhanced opioid reward after initial opioid exposure in rats. Psychopharmacology. PMID 33410983 DOI: 10.1007/s00213-020-05725-3  0.35
2020 Altarifi AA, Moerke MJ, Alsalem MI, Negus SS. Preclinical assessment of tramadol abuse potential: Effects of acute and repeated tramadol on intracranial self-stimulation in rats. Journal of Psychopharmacology (Oxford, England). 269881120944153. PMID 32842842 DOI: 10.1177/0269881120944153  0.379
2020 Bossert JM, Kiyatkin EA, Korah H, Hoots JK, Afzal A, Perekopskiy D, Thomas S, Fredriksson I, Blough BE, Negus SS, Epstein DH, Shaham Y. In a Rat Model of Opioid Maintenance, the G Protein-Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia. Biological Psychiatry. PMID 32305216 DOI: 10.1016/J.Biopsych.2020.02.014  0.331
2020 Townsend EA, Bremer P, Faunce K, Negus SS, Jaster A, Robinson H, Janda KD, Banks ML. Evaluation of a dual fentanyl/heroin vaccine on the antinociceptive and reinforcing effects of a fentanyl/heroin mixture in male and female rats. Acs Chemical Neuroscience. PMID 32271538 DOI: 10.1021/Acschemneuro.0C00064  0.317
2020 Townsend EA, Negus SS, Poklis JL, Banks ML. Lorcaserin maintenance fails to attenuate heroin vs. food choice in rhesus monkeys. Drug and Alcohol Dependence. 107848. PMID 31982193 DOI: 10.1016/j.drugalcdep.2020.107848  0.354
2019 Lile JA, Johnson AR, Banks ML, Hatton KW, Hays LR, Nicholson KL, Poklis JL, Rayapati AO, Rush CR, Stoops WW, Negus SS. Pharmacological validation of a translational model of cocaine use disorder: Effects of d-amphetamine maintenance on choice between intravenous cocaine and a nondrug alternative in humans and rhesus monkeys. Experimental and Clinical Psychopharmacology. PMID 31259593 DOI: 10.1037/Pha0000302  0.502
2019 Moerke MJ, Negus SS. Role of Agonist Efficacy in Exposure-Induced Enhancement of Mu Opioid Reward in Rats. Neuropharmacology. PMID 30880123 DOI: 10.1016/j.neuropharm.2019.03.020  0.393
2019 Townsend EA, Negus SS, Caine SB, Thomsen M, Banks ML. Sex differences in opioid reinforcement under a fentanyl vs. foodchoice procedure in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30818323 DOI: 10.1038/S41386-019-0356-1  0.569
2019 Sakloth F, Leggett E, Moerke MJ, Townsend EA, Banks ML, Negus SS. Effects of acute and repeated treatment with serotonin 5-HT2A receptor agonist hallucinogens on intracranial self-stimulation in rats. Experimental and Clinical Psychopharmacology. PMID 30628811 DOI: 10.1037/Pha0000253  0.367
2018 Negus SS, Freeman KB. Abuse Potential of Biased Mu Opioid Receptor Agonists. Trends in Pharmacological Sciences. 39: 916-919. PMID 30343727 DOI: 10.1016/J.Tips.2018.08.007  0.313
2018 Schwienteck KL, Negus SS, Banks ML. Sex differences in the effectiveness of buprenorphine to decrease rates of responding in rhesus monkeys. Behavioural Pharmacology. PMID 30212383 DOI: 10.1097/FBP.0000000000000437  0.379
2018 Moerke MJ, Ananthan S, Banks ML, Eltit JM, Freitas KC, Johnson AR, Saini SK, Steele TWE, Negus SS. Interactions Between Cocaine and the Putative Allosteric Dopamine Transporter Ligand SRI-31142. The Journal of Pharmacology and Experimental Therapeutics. PMID 30150482 DOI: 10.1124/jpet.118.250902  0.465
2018 Johnson AR, Banks ML, Selley DE, Negus SS. Amphetamine maintenance differentially modulates effects of cocaine, methylenedioxypyrovalerone (MDPV), and methamphetamine on intracranial self-stimulation and nucleus accumbens dopamine in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29703999 DOI: 10.1038/S41386-018-0071-3  0.453
2018 Sakloth F, Negus SS. Naltrexone maintenance fails to alter amphetamine effects on intracranial self-stimulation in rats. Experimental and Clinical Psychopharmacology. PMID 29528663 DOI: 10.1037/Pha0000183  0.491
2018 Legakis LP, Negus SS. Repeated Morphine Produces Sensitization to Reward and Tolerance to Antiallodynia in Male and Female Rats with Chemotherapy-Induced Neuropathy. The Journal of Pharmacology and Experimental Therapeutics. 365: 9-19. PMID 29363579 DOI: 10.1124/jpet.117.246215  0.384
2018 Cornelissen JC, Obeng S, Rice KC, Zhang Y, Negus SS, Banks M. Application of receptor theory to the design and use of fixed-proportion mu-opioid agonist and antagonist mixtures in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. PMID 29330156 DOI: 10.1124/Jpet.117.246439  0.329
2017 Moerke MJ, Banks ML, Cheng K, Rice KC, Negus SS. Maintenance on naltrexone+amphetamine decreases cocaine-vs.-food choice in male rhesus monkeys. Drug and Alcohol Dependence. 181: 85-93. PMID 29040826 DOI: 10.1016/J.Drugalcdep.2017.09.020  0.547
2017 Townsend EA, Naylor JE, Negus SS, Edwards SR, Qureshi HN, McLendon HW, McCurdy CR, Kapanda CN, do Carmo JM, da Silva FS, Hall JE, Sufka KJ, Freeman KB. Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats. Psychopharmacology. PMID 28567699 DOI: 10.1007/S00213-017-4652-3  0.351
2017 Thomsen M, Barrett AC, Butler P, Negus SS, Caine SB. Effects of acute and chronic treatments with D2 and D3 receptor ligands on cocaine vs. food choice in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 28473458 DOI: 10.1124/jpet.117.241141  0.618
2017 Lazenka MF, Negus SS. Oral modafinil facilitates intracranial self-stimulation in rats: comparison with methylphenidate. Behavioural Pharmacology. 28: 318-322. PMID 28125506 DOI: 10.1097/FBP.0000000000000288  0.389
2016 Banks ML, Negus SS. Repeated 7-Day Treatment with the 5-HT2C Agonist Lorcaserin or the 5-HT2A Antagonist Pimavanserin Alone or in Combination Fails to Reduce Cocaine vs. Food Choice in Male Rhesus Monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27857126 DOI: 10.1038/npp.2016.259  0.507
2016 Negus SS, Banks ML. Decoding the Structure of Abuse Potential for New Psychoactive Substances: Structure-Activity Relationships for Abuse-Related Effects of 4-Substituted Methcathinone Analogs. Current Topics in Behavioral Neurosciences. PMID 27696217 DOI: 10.1007/7854_2016_18  0.302
2016 Hutsell BA, Negus SS, Banks ML. Effects of 21-day d-amphetamine and risperidone treatment on cocaine vs food choice and extended-access cocaine intake in male rhesus monkeys. Drug and Alcohol Dependence. 168: 36-44. PMID 27615401 DOI: 10.1016/j.drugalcdep.2016.08.637  0.488
2016 Lile JA, Stoops WW, Rush CR, Negus SS, Glaser PE, Hatton KW, Hays LR. Development of a translational model to screen medications for cocaine use disorder II: Choice between intravenous cocaine and money in humans. Drug and Alcohol Dependence. PMID 27269368 DOI: 10.1016/J.Drugalcdep.2016.05.022  0.374
2016 Johnson AR, Banks ML, Blough BE, Lile JA, Nicholson KL, Negus SS. Development of a translational model to screen medications for cocaine use disorder I: Choice between cocaine and food in rhesus monkeys. Drug and Alcohol Dependence. PMID 27264165 DOI: 10.1016/j.drugalcdep.2016.05.021  0.45
2016 Smith DA, Negus SS, Poklis JL, Blough BE, Banks ML. Cocaine-like discriminative stimulus effects of alpha-pyrrolidinovalerophenone, methcathinone and their 3,4-methylenedioxy or 4-methyl analogs in rhesus monkeys. Addiction Biology. PMID 27060605 DOI: 10.1111/adb.12399  0.423
2016 Lazenka MF, Legakis LP, Negus SS. Opposing effects of dopamine D1- and D2-like agonists on intracranial self-stimulation in male rats. Experimental and Clinical Psychopharmacology. 24: 193-205. PMID 26987070 DOI: 10.1037/pha0000067  0.368
2016 Banks ML, Bauer CT, Negus SS, Blough BE. Cocaine-like discriminative stimulus effects of phendimetrazine and phenmetrazine in rats. Behavioural Pharmacology. PMID 26866973 DOI: 10.1097/FBP.0000000000000225  0.504
2015 Miller LL, Altarifi AA, Negus SS. Effects of repeated morphine on intracranial self-stimulation in male rats in the absence or presence of a noxious pain stimulus. Experimental and Clinical Psychopharmacology. 23: 405-14. PMID 26375515 DOI: 10.1037/pha0000042  0.367
2015 Schwienteck KL, Negus SS, Poklis JL, Banks ML. Effects of continuous nicotine treatment and subsequent termination on cocaine versus food choice in male rhesus monkeys. Experimental and Clinical Psychopharmacology. 23: 395-404. PMID 26098473 DOI: 10.1037/pha0000023  0.456
2015 Banks ML, Hutsell BA, Schwienteck KL, Negus SS. Use of Preclinical Drug vs. Food Choice Procedures to Evaluate Candidate Medications for Cocaine Addiction. Current Treatment Options in Psychiatry. 2: 136-150. PMID 26009706 DOI: 10.1007/s40501-015-0042-9  0.426
2015 Lazenka MF, Moeller FG, Negus SS. Effects of caffeine and its metabolite paraxanthine on intracranial self-stimulation in male rats. Experimental and Clinical Psychopharmacology. 23: 71-80. PMID 25844631 DOI: 10.1037/Pha0000012  0.442
2015 Banks ML, Hutsell BA, Blough BE, Poklis JL, Negus SS. Preclinical Assessment of Lisdexamfetamine as an Agonist Medication Candidate for Cocaine Addiction: Effects in Rhesus Monkeys Trained to Discriminate Cocaine or to Self-Administer Cocaine in a Cocaine Versus Food Choice Procedure. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25618405 DOI: 10.1093/ijnp/pyv009  0.526
2015 Hutsell BA, Cheng K, Rice KC, Negus SS, Banks ML. Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys. Addiction Biology. PMID 25581305 DOI: 10.1111/Adb.12206  0.519
2015 Negus SS, Henningfield J. Agonist Medications for the Treatment of Cocaine Use Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1815-25. PMID 25563633 DOI: 10.1038/Npp.2014.322  0.404
2015 Hutsell BA, Negus SS, Banks ML. A generalized matching law analysis of cocaine vs. food choice in rhesus monkeys: effects of candidate 'agonist-based' medications on sensitivity to reinforcement. Drug and Alcohol Dependence. 146: 52-60. PMID 25439054 DOI: 10.1016/j.drugalcdep.2014.11.003  0.519
2014 Hillhouse TM, Porter JH, Negus SS. Comparison of antidepressant-like and abuse-related effects of phencyclidine in rats. Drug Development Research. 75: 479-88. PMID 25315690 DOI: 10.1002/Ddr.21228  0.365
2014 Bauer CT, Banks ML, Negus SS. The effect of chronic amphetamine treatment on cocaine-induced facilitation of intracranial self-stimulation in rats. Psychopharmacology. 231: 2461-70. PMID 24408209 DOI: 10.1007/s00213-013-3405-1  0.451
2014 Leitl MD, Onvani S, Bowers MS, Cheng K, Rice KC, Carlezon WA, Banks ML, Negus SS. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 614-24. PMID 24008352 DOI: 10.1038/Npp.2013.236  0.306
2013 Banks ML, Blough BE, Fennell TR, Snyder RW, Negus SS. Effects of phendimetrazine treatment on cocaine vs food choice and extended-access cocaine consumption in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2698-707. PMID 23893022 DOI: 10.1038/npp.2013.180  0.506
2013 Altarifi AA, Rice KC, Negus SS. Abuse-related effects of μ-opioid analgesics in an assay of intracranial self-stimulation in rats: Modulation by chronic morphine exposure Behavioural Pharmacology. 24: 459-470. PMID 23881045 DOI: 10.1097/Fbp.0B013E328364C0Bd  0.349
2013 Kaufman MJ, Janes AC, Frederick Bd, Brimson-Théberge M, Tong Y, McWilliams SB, Bear A, Gillis TE, Schrode KM, Renshaw PF, Negus SS. A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys. Experimental and Clinical Psychopharmacology. 21: 323-31. PMID 23773004 DOI: 10.1037/A0033062  0.376
2013 Banks ML, Blough BE, Negus SS. Effects of 14-day treatment with the schedule III anorectic phendimetrazine on choice between cocaine and food in rhesus monkeys. Drug and Alcohol Dependence. 131: 204-13. PMID 23726979 DOI: 10.1016/j.drugalcdep.2013.05.005  0.521
2013 Thomsen M, Barrett AC, Negus SS, Caine SB. Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine. Journal of the Experimental Analysis of Behavior. 99: 211-33. PMID 23319458 DOI: 10.1002/Jeab.15  0.617
2013 Banks ML, Blough BE, Fennell TR, Snyder RW, Negus SS. Role of phenmetrazine as an active metabolite of phendimetrazine: evidence from studies of drug discrimination and pharmacokinetics in rhesus monkeys. Drug and Alcohol Dependence. 130: 158-66. PMID 23211394 DOI: 10.1016/j.drugalcdep.2012.10.026  0.479
2013 Negus SS, Banks ML. Medications development for opioid abuse. Cold Spring Harbor Perspectives in Medicine. 3: a012104. PMID 23125072 DOI: 10.1101/cshperspect.a012104  0.308
2013 Banks ML, Blough BE, Negus SS. Interaction between behavioral and pharmacological treatment strategies to decrease cocaine choice in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 395-404. PMID 22968813 DOI: 10.1038/npp.2012.193  0.514
2013 Negus S, Banks M, Blough B, Fennell T, Snyder R. C.6 - CHRONIC PHENDIMETRAZINE TREATMENT REDUCES COCAINE VS. FOOD CHOICE AND EXTENDED-ACCESS COCAINE CONSUMPTION BY RHESUS MONKEYS Behavioural Pharmacology. 24: e31-e32. DOI: 10.1097/01.fbp.0000434790.41430.54  0.461
2013 Banks ML, Blough BE, Negus SS. Corrigendum to "Effects of 14-day treatment with the schedule III anorectic phendimetrazine on choice between cocaine and food in rhesus monkeys" [Drug Alcohol Depend. 131 (2013) 204-213] Drug and Alcohol Dependence. 133: 794. DOI: 10.1016/j.drugalcdep.2013.08.005  0.394
2012 Aceto MD, Harris LS, Negus SS, Banks ML, Hughes LD, Akgün E, Portoghese PS. MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys. International Journal of Medicinal Chemistry. 2012: 327257. PMID 25954526 DOI: 10.1155/2012/327257  0.337
2012 Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys. Acs Chemical Neuroscience. 3: 720-7. PMID 23019498 DOI: 10.1021/Cn300049M  0.303
2012 Altarifi AA, Miller LL, Negus SS. Role of µ-opioid receptor reserve and µ-agonist efficacy as determinants of the effects of µ-agonists on intracranial self-stimulation in rats. Behavioural Pharmacology. 23: 678-92. PMID 22914074 DOI: 10.1097/FBP.0b013e328358593c  0.332
2012 Negus SS, Morrissey EM, Folk JE, Rice KC. Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys. Pain Research and Treatment. 2012: 867067. PMID 22666579 DOI: 10.1155/2012/867067  0.329
2011 Banks ML, Blough BE, Negus SS. Effects of monoamine releasers with varying selectivity for releasing dopamine/norepinephrine versus serotonin on choice between cocaine and food in rhesus monkeys. Behavioural Pharmacology. 22: 824-36. PMID 22015808 DOI: 10.1097/FBP.0b013e32834d63ac  0.491
2011 Altarifi AA, Negus SS. Some determinants of morphine effects on intracranial self-stimulation in rats: dose, pretreatment time, repeated treatment, and rate dependence. Behavioural Pharmacology. 22: 663-73. PMID 21921839 DOI: 10.1097/FBP.0b013e32834aff54  0.364
2011 Banks ML, Roma PG, Folk JE, Rice KC, Negus SS. Effects of the delta-opioid agonist SNC80 on the abuse liability of methadone in rhesus monkeys: a behavioral economic analysis. Psychopharmacology. 216: 431-9. PMID 21369752 DOI: 10.1007/S00213-011-2235-2  0.539
2010 Newman JL, Negus SS, Lozama A, Prisinzano TE, Mello NK. Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys. Experimental and Clinical Psychopharmacology. 18: 395-408. PMID 20939643 DOI: 10.1037/A0021042  0.522
2010 Banks ML, Folk JE, Rice KC, Negus SS. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacology, Biochemistry, and Behavior. 97: 205-12. PMID 20678514 DOI: 10.1016/J.Pbb.2010.07.019  0.353
2010 Banks ML, Rice KC, Negus SS. Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 335: 497-505. PMID 20675432 DOI: 10.1124/Jpet.110.169276  0.327
2010 Negus SS, Banks ML, Folk JE, Rice KC. Modulation of delta opioid agonist-induced antinociception by repeated morphine pretreatment in rhesus monkeys. Life Sciences. 86: 385-92. PMID 20096291 DOI: 10.1016/J.Lfs.2010.01.006  0.368
2010 Banks ML, Negus SS. Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 493-504. PMID 19776729 DOI: 10.1038/npp.2009.154  0.521
2009 Negus SS, Baumann MH, Rothman RB, Mello NK, Blough BE. Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine. The Journal of Pharmacology and Experimental Therapeutics. 329: 272-81. PMID 19151247 DOI: 10.1124/Jpet.108.143701  0.481
2009 Do Carmo GP, Folk JE, Rice KC, Chartoff E, Carlezon WA, Negus SS. The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats. European Journal of Pharmacology. 604: 58-65. PMID 19133255 DOI: 10.1016/J.Ejphar.2008.12.021  0.383
2009 Negus SS, Bear AE, Folk JE, Rice KC. Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys. European Journal of Pharmacology. 602: 92-100. PMID 19027735 DOI: 10.1016/J.Ejphar.2008.11.004  0.339
2009 Negus SS, Mello NK, Kimmel HL, Howell LL, Carroll FI. Effects of the monoamine uptake inhibitors RTI-112 and RTI-113 on cocaine- and food-maintained responding in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 91: 333-8. PMID 18755212 DOI: 10.1016/j.pbb.2008.08.002  0.492
2009 Negus SS, Rice KC. Mechanisms of withdrawal-associated increases in heroin self-administration: Pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys Neuropsychopharmacology. 34: 899-911. PMID 18704098 DOI: 10.1038/Npp.2008.127  0.426
2008 Negus SS, Schrode K, Stevenson GW. Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability. Experimental and Clinical Psychopharmacology. 16: 386-99. PMID 18837635 DOI: 10.1037/a0013088  0.435
2008 Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 326: 939-48. PMID 18511649 DOI: 10.1124/Jpet.108.138180  0.313
2008 Kimmel HL, Negus SS, Wilcox KM, Ewing SB, Stehouwer J, Goodman MM, Votaw JR, Mello NK, Carroll FI, Howell LL. Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 90: 453-62. PMID 18468667 DOI: 10.1016/J.Pbb.2008.03.032  0.385
2008 Mello NK, Negus SS, Knudson IM, Kelly M, Mendelson JH. Effects of estradiol on cocaine self-administration and cocaine discrimination by female rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 783-95. PMID 17507915 DOI: 10.1038/Sj.Npp.1301451  0.487
2007 Schindler CW, Graczyk Z, Gilman JP, Negus SS, Bergman J, Mello NK, Goldberg SR. Effects of kappa opioid agonists alone and in combination with cocaine on heart rate and blood pressure in conscious squirrel monkeys. European Journal of Pharmacology. 576: 107-13. PMID 17707792 DOI: 10.1016/J.Ejphar.2007.07.053  0.442
2007 Zernig G, Ahmed SH, Cardinal RN, Morgan D, Acquas E, Foltin RW, Vezina P, Negus SS, Crespo JA, Stöckl P, Grubinger P, Madlung E, Haring C, Kurz M, Saria A. Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests. Pharmacology. 80: 65-119. PMID 17570954 DOI: 10.1159/000103923  0.381
2007 Mello NK, Negus SS. Effects of d-amphetamine and buprenorphine combinations on speedball (cocaine+heroin) self-administration by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1985-94. PMID 17228335 DOI: 10.1038/Sj.Npp.1301319  0.479
2007 Negus SS, Mello NK, Blough BE, Baumann MH, Rothman RB. Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 320: 627-36. PMID 17071819 DOI: 10.1124/Jpet.106.107383  0.468
2006 Mello NK, Negus SS, Rice KC, Mendelson JH. Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 85: 744-51. PMID 17182090 DOI: 10.1016/J.Pbb.2006.11.008  0.505
2006 Danielsson I, Gasior M, Stevenson GW, Folk JE, Rice KC, Negus SS. Electroencephalographic and convulsant effects of the delta opioid agonist SNC80 in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 85: 428-34. PMID 17112570 DOI: 10.1016/J.Pbb.2006.09.012  0.306
2006 Do Carmo GP, Mello NK, Rice KC, Folk JE, Negus SS. Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology. 547: 92-100. PMID 16934797 DOI: 10.1016/J.Ejphar.2006.06.075  0.545
2006 Terner JM, Barrett AC, Lomas LM, Negus SS, Picker MJ. Influence of low doses of naltrexone on morphine antinociception and morphine tolerance in male and female rats of four strains. Pain. 122: 90-101. PMID 16527399 DOI: 10.1016/J.Pain.2006.01.019  0.322
2006 Negus SS. Choice between heroin and food in nondependent and heroin-dependent rhesus monkeys: effects of naloxone, buprenorphine, and methadone. The Journal of Pharmacology and Experimental Therapeutics. 317: 711-23. PMID 16456085 DOI: 10.1124/jpet.105.095380  0.437
2005 Mathews JL, Peng X, Xiong W, Zhang A, Negus SS, Neumeyer JL, Bidlack JM. Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties. The Journal of Pharmacology and Experimental Therapeutics. 315: 821-7. PMID 16076937 DOI: 10.1124/jpet.105.084343  0.32
2005 Barrett AC, Negus SS, Mello NK, Caine SB. Effect of GABA agonists and GABA-A receptor modulators on cocaine- and food-maintained responding and cocaine discrimination in rats. The Journal of Pharmacology and Experimental Therapeutics. 315: 858-71. PMID 16033912 DOI: 10.1124/Jpet.105.086033  0.468
2005 Negus SS. Effects of punishment on choice between cocaine and food in rhesus monkeys. Psychopharmacology. 181: 244-52. PMID 15856185 DOI: 10.1007/s00213-005-2266-7  0.356
2005 Stevenson GW, Folk JE, Rice KC, Negus SS. Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and heroin. The Journal of Pharmacology and Experimental Therapeutics. 314: 221-31. PMID 15792997 DOI: 10.1124/Jpet.104.082685  0.4
2005 Rothman RB, Blough BE, Woolverton WL, Anderson KG, Negus SS, Mello NK, Roth BL, Baumann MH. Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration. The Journal of Pharmacology and Experimental Therapeutics. 313: 1361-9. PMID 15761112 DOI: 10.1124/Jpet.104.082503  0.335
2005 Negus SS. Interactions between the reinforcing effects of cocaine and heroin in a drug-vs-food choice procedure in rhesus monkeys: a dose-addition analysis. Psychopharmacology. 180: 115-24. PMID 15696330 DOI: 10.1007/s00213-004-2133-y  0.486
2004 Stevenson GW, Wentland MP, Bidlack JM, Mello NK, Negus SS. Effects of the mixed-action kappa/mu opioid agonist 8-carboxamidocyclazocine on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology. 506: 133-41. PMID 15588733 DOI: 10.1016/J.Ejphar.2004.10.051  0.538
2004 Grabowski J, Shearer J, Merrill J, Negus SS. Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence. Addictive Behaviors. 29: 1439-64. PMID 15345275 DOI: 10.1016/j.addbeh.2004.06.018  0.346
2004 Mello NK, Mendelson JH, Negus SS, Kelly M, Knudson I, Roth ME. The effects of cocaine on gonadal steroid hormones and LH in male and female rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2024-34. PMID 15199372 DOI: 10.1038/Sj.Npp.1300511  0.433
2004 Negus SS, Mello NK. Effects of chronic methadone treatment on cocaine- and food-maintained responding under second-order, progressive-ratio and concurrent-choice schedules in rhesus monkeys. Drug and Alcohol Dependence. 74: 297-309. PMID 15194208 DOI: 10.1016/J.Drugalcdep.2004.01.006  0.529
2004 Negus SS. Effects of the kappa opioid agonist U50,488 and the kappa opioid antagonist nor-binaltorphimine on choice between cocaine and food in rhesus monkeys. Psychopharmacology. 176: 204-13. PMID 15112031 DOI: 10.1007/s00213-004-1878-7  0.494
2004 Caine SB, Bowen CA, Yu G, Zuzga D, Negus SS, Mello NK. Effect of gonadectomy and gonadal hormone replacement on cocaine self-administration in female and male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 929-42. PMID 14735136 DOI: 10.1038/Sj.Npp.1300387  0.511
2004 Mello NK, Mendelson JH, Negus SS, Kelly M. Ovarian steroid hormone modulation of the acute effects of cocaine on luteinizing hormone and prolactin levels in ovariectomized rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 308: 156-67. PMID 14566011 DOI: 10.1124/Jpet.103.057216  0.441
2003 Stevenson GW, Folk JE, Linsenmayer DC, Rice KC, Negus SS. Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. The Journal of Pharmacology and Experimental Therapeutics. 307: 1054-64. PMID 14557380 DOI: 10.1124/Jpet.103.056515  0.352
2003 Negus SS, Mello NK. Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys. Drug and Alcohol Dependence. 70: 39-52. PMID 12681524 DOI: 10.1016/S0376-8716(02)00339-3  0.549
2003 Negus SS, Brandt MR, Gatch MB, Mello NK. Effects of heroin and its metabolites on schedule-controlled responding and thermal nociception in rhesus monkeys: sensitivity to antagonism by quadazocine, naltrindole and beta-funaltrexamine. Drug and Alcohol Dependence. 70: 17-27. PMID 12681522 DOI: 10.1016/S0376-8716(02)00331-9  0.342
2003 Negus SS, Mello NK. Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a progressive-ratio schedule in rhesus monkeys. Psychopharmacology. 167: 324-32. PMID 12652348 DOI: 10.1007/s00213-003-1409-y  0.534
2003 Bowen CA, Negus SS, Zong R, Neumeyer JL, Bidlack JM, Mello NK. Effects of mixed-action kappa/mu opioids on cocaine self-administration and cocaine discrimination by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1125-39. PMID 12637953 DOI: 10.1038/Sj.Npp.1300105  0.536
2003 Negus SS. Rapid assessment of choice between cocaine and food in rhesus monkeys: effects of environmental manipulations and treatment with d-amphetamine and flupenthixol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 919-31. PMID 12637948 DOI: 10.1038/sj.npp.1300096  0.519
2002 Negus SS, Zuzga DS, Mello NK. Sex differences in opioid antinociception in rhesus monkeys: antagonism of fentanyl and U50,488 by quadazocine. The Journal of Pain : Official Journal of the American Pain Society. 3: 218-26. PMID 14622776 DOI: 10.1054/Jpai.2002.124734  0.33
2002 Negus SS, Bidlack JM, Mello NK, Furness MS, Rice KC, Brandt MR. Delta opioid antagonist effects of buprenorphine in rhesus monkeys. Behavioural Pharmacology. 13: 557-70. PMID 12409994 DOI: 10.1097/00008877-200211000-00005  0.326
2002 Negus SS, Mello NK, Linsenmayer DC, Jones RM, Portoghese PS. Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys. Psychopharmacology. 163: 412-9. PMID 12373442 DOI: 10.1007/S00213-002-1038-X  0.365
2002 Bowen CA, Fischer BD, Mello NK, Negus SS. Antagonism of the antinociceptive and discriminative stimulus effects of heroin and morphine by 3-methoxynaltrexone and naltrexone in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 302: 264-73. PMID 12065726 DOI: 10.1124/Jpet.302.1.264  0.359
2002 Caine SB, Negus SS, Mello NK, Patel S, Bristow L, Kulagowski J, Vallone D, Saiardi A, Borrelli E. Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2977-88. PMID 11923462 DOI: 10.1523/Jneurosci.22-07-02977.2002  0.423
2002 Negus SS, Mello NK. Effects of gonadal steroid hormone treatments on opioid antinociception in ovariectomized rhesus monkeys. Psychopharmacology. 159: 275-83. PMID 11862360 DOI: 10.1007/S002130100912  0.323
2002 Negus SS, Mello NK. Effects of mu-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: role of mu-agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 300: 1111-21. PMID 11861822 DOI: 10.1124/Jpet.300.3.1111  0.561
2002 Bowen CA, Negus SS, Kelly M, Mello NK. The effects of heroin on prolactin levels in male rhesus monkeys: use of cumulative-dosing procedures. Psychoneuroendocrinology. 27: 319-36. PMID 11818169 DOI: 10.1016/S0306-4530(01)00053-1  0.355
2001 Brandt MR, Furness MS, Rice KC, Fischer BD, Negus SS. Studies of tolerance and dependence with the delta-opioid agonist SNC80 in rhesus monkeys responding under a schedule of food presentation. The Journal of Pharmacology and Experimental Therapeutics. 299: 629-37. PMID 11602675  0.381
2001 Neumeyer JL, Gu XH, van Vliet LA, DeNunzio NJ, Rusovici DE, Cohen DJ, Negus SS, Mello NK, Bidlack JM. Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. Bioorganic & Medicinal Chemistry Letters. 11: 2735-40. PMID 11591513 DOI: 10.1016/S0960-894X(01)00543-1  0.31
2001 Negus SS, Pope HG, Kanayama G, Wines JD, Fischer BD. Lack of evidence for opioid tolerance or dependence in rhesus monkeys following high-dose anabolic-androgenic steroid administration. Psychoneuroendocrinology. 26: 789-96. PMID 11585679 DOI: 10.1016/S0306-4530(01)00028-2  0.367
2001 Mello NK, Negus SS. Effects of indatraline and buprenorphine on self-administration of speedball combinations of cocaine and heroin by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 104-17. PMID 11377924 DOI: 10.1016/S0893-133X(00)00247-5  0.44
2001 Brandt MR, Furness MS, Mello NK, Rice KC, Negus SS. Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity. The Journal of Pharmacology and Experimental Therapeutics. 296: 939-46. PMID 11181927  0.311
2000 Negus SS, Mello NK, Fivel PA. Effects of GABA agonists and GABA-A receptor modulators on cocaine discrimination in rhesus monkeys. Psychopharmacology. 152: 398-407. PMID 11140332 DOI: 10.1007/S002130000543  0.414
2000 Caine SB, Negus SS, Mello NK, Bergman J. Effects of dopamine D1-like and D2-like agonists in rats trained to discriminate cocaine from saline: influence of experimental history. Experimental and Clinical Psychopharmacology. 8: 404-14. PMID 10975632 DOI: 10.1037//1064-1297.8.3.404  0.495
2000 Mello NK, Negus SS. Interactions between kappa opioid agonists and cocaine. Preclinical studies. Annals of the New York Academy of Sciences. 909: 104-32. PMID 10911926 DOI: 10.1111/J.1749-6632.2000.Tb06678.X  0.535
2000 Neumeyer JL, Mello NK, Negus SS, Bidlack JM. Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse. Pharmaceutica Acta Helvetiae. 74: 337-44. PMID 10812979 DOI: 10.1016/S0031-6865(99)00044-8  0.317
2000 Caine SB, Negus SS, Mello NK. Effects of dopamine D(1-like) and D(2-like) agonists on cocaine self-administration in rhesus monkeys: rapid assessment of cocaine dose-effect functions. Psychopharmacology. 148: 41-51. PMID 10663416 DOI: 10.1007/S002130050023  0.524
2000 Caine SB, Negus SS, Mello NK, Bergman J. Effects of dopamine D₁-like and D₂-like agonists in rats trained to discriminate cocaine from saline: Influence of experimental history. Experimental and Clinical Psychopharmacology. 8: 404-414. DOI: 10.1037/1064-1297.8.3.404  0.4
1999 Negus SS, Mello NK. Effects of kappa opioid agonists on the discriminative stimulus effects of cocaine in rhesus monkeys. Experimental and Clinical Psychopharmacology. 7: 307-17. PMID 10609965 DOI: 10.1037//1064-1297.7.4.307  0.517
1999 Caine SB, Negus SS, Mello NK. Method for training operant responding and evaluating cocaine self-administration behavior in mutant mice. Psychopharmacology. 147: 22-4. PMID 10591861 DOI: 10.1007/S002130051134  0.322
1999 Caine SB, Negus SS, Mello NK, Bergman J. Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine. The Journal of Pharmacology and Experimental Therapeutics. 291: 353-60. PMID 10490924  0.501
1999 Negus SS, Brandt MR, Mello NK. Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 291: 60-9. PMID 10490887  0.504
1999 Mello NK, Negus SS. Effects of flupenthixol and quadazocine on self-administration of speedball combinations of cocaine and heroin by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 575-88. PMID 10481841 DOI: 10.1016/S0893-133X(99)00056-1  0.508
1999 Brandt MR, Negus SS, Mello NK, Furness MS, Zhang X, Rice KC. Discriminative stimulus effects of the nonpeptidic delta-opioid agonist SNC80 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 290: 1157-64. PMID 10454490  0.413
1999 Negus SS, Mello NK. Opioid antinociception in ovariectomized monkeys: comparison with antinociception in males and effects of estradiol replacement. The Journal of Pharmacology and Experimental Therapeutics. 290: 1132-40. PMID 10454487  0.35
1999 Mendelson JH, Mello NK, Negus SS. Effects of luteinizing hormone-releasing hormone on plasma cocaine levels in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 289: 791-9. PMID 10215654  0.431
1999 Gatch MB, Negus SS, Mello NK. Antinociceptive effects of cocaine in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 62: 291-7. PMID 9972696 DOI: 10.1016/S0091-3057(98)00163-4  0.52
1998 Mello NK, Negus SS. Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 286: 812-24. PMID 9694938  0.52
1998 Negus SS, Gatch MB, Mello NK, Zhang X, Rice K. Behavioral effects of the delta-selective opioid agonist SNC80 and related compounds in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 286: 362-75. PMID 9655881  0.509
1998 Lamas X, Negus SS, Gatch MB, Mello NK. Effects of heroin/cocaine combinations in rats trained to discriminate heroin or cocaine from saline. Pharmacology, Biochemistry, and Behavior. 60: 357-64. PMID 9632217 DOI: 10.1016/S0091-3057(98)00021-5  0.476
1998 Negus SS, Gatch MB, Mello NK. Discriminative stimulus effects of a cocaine/heroin "speedball" combination in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 285: 1123-36. PMID 9618415  0.523
1998 Mello NK, Negus SS. The effects of buprenorphine on self-administration of cocaine and heroin "speedball" combinations and heroin alone by rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 285: 444-56. PMID 9580582  0.474
1998 Negus SS, Gatch MB, Mello NK. Effects of mu opioid agonists alone and in combination with cocaine and D-amphetamine in rhesus monkeys trained to discriminate cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 325-38. PMID 9536446 DOI: 10.1016/S0893-133X(97)00163-2  0.546
1998 Gatch MB, Negus SS, Mello NK. Antinociceptive effects of monoamine reuptake inhibitors administered alone or in combination with mu opioid agonists in rhesus monkeys. Psychopharmacology. 135: 99-106. PMID 9489939 DOI: 10.1007/S002130050490  0.452
1997 Negus SS, Mello NK, Portoghese PS, Lin CE. Effects of kappa opioids on cocaine self-administration by rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 282: 44-55. PMID 9223538  0.549
1996 Negus SS, Morgan D, Cook CD, Picker MJ. Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure. Psychopharmacology. 126: 199-205. PMID 8876019 DOI: 10.1007/Bf02246449  0.35
1996 Gatch MB, Liguori A, Negus SS, Mello NK, Bergman J, Liguori T. Naloxonazine antagonism of levorphanol-induced antinociception and respiratory depression in rhesus monkeys. European Journal of Pharmacology. 298: 31-6. PMID 8867916 DOI: 10.1016/0014-2999(95)00769-5  0.327
1996 Butelman ER, Negus SS, Lewis JW, Woods JH. Clocinnamox antagonism of opioid suppression of schedule-controlled responding in rhesus monkeys. Psychopharmacology. 123: 320-4. PMID 8867870 DOI: 10.1007/Bf02246641  0.355
1996 Gatch MB, Negus SS, Mello NK, Archer S, Bidlack JM. Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 278: 1282-9. PMID 8819513  0.371
1996 Negus SS, Mello NK, Lamas X, Mendelson JH. Acute and chronic effects of flupenthixol on the discriminative stimulus and reinforcing effects of cocaine in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 278: 879-90. PMID 8768743  0.528
1996 Lamas X, Negus SS, Nader MA, Mello NK. Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline. Psychopharmacology. 124: 306-14. PMID 8739545 DOI: 10.1007/Bf02247435  0.503
1996 Mello NK, Negus SS. Preclinical evaluation of pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 14: 375-424. PMID 8726752 DOI: 10.1016/0893-133X(95)00274-H  0.344
1995 Negus SS, Mello NK, Lukas SE, Mendelson JH. Diurnal patterns of cocaine and heroin self-administration in rhesus monkeys responding under a schedule of multiple daily sessions. Behavioural Pharmacology. 6: 763-775. PMID 11224379  0.475
1995 Lamas X, Negus SS, Hall E, Mello NK. Relationship between the discriminative stimulus effects and plasma concentrations of intramuscular cocaine in rhesus monkeys. Psychopharmacology. 121: 331-8. PMID 8584615 DOI: 10.1007/Bf02246072  0.452
1995 Gatch MB, Negus SS, Butelman ER, Mello NK. Antinociceptive effects of cocaine/opioid combinations in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 275: 1346-54. PMID 8531102  0.497
1995 Winger GD, Yasar S, Negus SS, Goldberg SR. Intravenous self-administration studies with l-deprenyl (selegiline) in monkeys. Clinical Pharmacology and Therapeutics. 56: 774-80. PMID 7995020 DOI: 10.1038/clpt.1994.208  0.399
1995 Negus SS, Mello NK, Portoghese PS, Lukas SE, Mendelson JH. Role of delta opioid receptors in the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 273: 1245-56. PMID 7791097  0.54
1995 Mello NK, Negus SS, Lukas SE, Mendelson JH, Sholar JW, Drieze J. A primate model of polydrug abuse: cocaine and heroin combinations. The Journal of Pharmacology and Experimental Therapeutics. 274: 1325-37. PMID 7562505  0.504
1995 Butelman ER, Negus SS, Gatch MB, Chang KJ, Woods JH. BW373U86, a delta-opioid receptor agonist, reverses bradykinin-induced thermal allodynia in rhesus monkeys. European Journal of Pharmacology. 277: 285-7. PMID 7493622 DOI: 10.1016/0014-2999(95)00134-7  0.325
1994 Takasuna M, Negus SS, DeCosta BR, Woods JH. Opioid pharmacology of the antinociceptive effects of loperamide in mice. Behavioural Pharmacology. 5: 189-195. PMID 11224267 DOI: 10.1097/00008877-199404000-00010  0.322
1994 Negus SS, Butelman ER, Chang KJ, DeCosta B, Winger G, Woods JH. Behavioral effects of the systemically active delta opioid agonist BW373U86 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 270: 1025-34. PMID 7932149  0.346
1994 Broadbear JH, Negus SS, Butelman ER, de Costa BR, Woods JH. Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on kappa-opioid agonists in the mouse writhing assay. Psychopharmacology. 115: 311-9. PMID 7871070 DOI: 10.1007/Bf02245071  0.332
1993 Negus SS, Pasternak GW, Koob GF, Weinger MB. Antagonist effects of beta-funaltrexamine and naloxonazine on alfentanil-induced antinociception and muscle rigidity in the rat. The Journal of Pharmacology and Experimental Therapeutics. 264: 739-45. PMID 8437122  0.307
1993 Negus SS, Henriksen SJ, Mattox A, Pasternak GW, Portoghese PS, Takemori AE, Weinger MB, Koob GF. Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats. The Journal of Pharmacology and Experimental Therapeutics. 265: 1245-52. PMID 8389859  0.372
1993 Negus SS, Butelman ER, Al Y, Woods JH. Prostaglandin E2-induced thermal hyperalgesia and its reversal by morphine in the warm-water tail-withdrawal procedure in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 266: 1355-63. PMID 8371142  0.339
1993 Butelman ER, Negus SS, Ai Y, de Costa BR, Woods JH. Kappa opioid antagonist effects of systemically administered nor-binaltorphimine in a thermal antinociception assay in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 267: 1269-76. PMID 8263790  0.337
1993 Negus SS, Burke TF, Medzihradsky F, Woods JH. Effects of opioid agonists selective for mu, kappa and delta opioid receptors on schedule-controlled responding in rhesus monkeys: antagonism by quadazocine. The Journal of Pharmacology and Experimental Therapeutics. 267: 896-903. PMID 8246165  0.346
1993 Maldonado R, Negus S, Koob GF. Precipitation of morphine withdrawal syndrome in rats by administration of mu-, delta- and kappa-selective opioid antagonists. Neuropharmacology. 31: 1231-41. PMID 1335131 DOI: 10.1016/0028-3908(92)90051-P  0.371
1992 Picker MJ, Craft RM, Negus SS, Powell KR, Mattox SR, Jones SR, Hargrove BK, Dykstra LA. Intermediate efficacy mu opioids: examination of their morphine-like stimulus effects and response rate-decreasing effects in morphine-tolerant rats. The Journal of Pharmacology and Experimental Therapeutics. 263: 668-81. PMID 1331411  0.324
1991 Picker MJ, Negus SS, Powell KR. Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation. Psychopharmacology. 103: 129-35. PMID 1848712 DOI: 10.1007/BF02244087  0.372
1990 Picker MJ, Negus SS, Craft RM. Butorphanol's efficacy at mu and kappa opioid receptors: inferences based on the schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rats under a drug discrimination procedure. Pharmacology, Biochemistry, and Behavior. 36: 563-8. PMID 2165617 DOI: 10.1016/0091-3057(90)90256-H  0.356
1990 Picker MJ, Doty P, Negus SS, Mattox SR, Dykstra LA. Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists. The Journal of Pharmacology and Experimental Therapeutics. 254: 13-22. PMID 2164087  0.315
1990 Negus SS, Picker MJ, Dykstra LA. Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure. Psychopharmacology. 102: 465-73. PMID 1965748 DOI: 10.1007/BF02247126  0.339
1989 Negus SS, Picker MJ, Dykstra LA. Kappa antagonist properties of buprenorphine in non-tolerant and morphine-tolerant rats. Psychopharmacology. 98: 141-3. PMID 2543017 DOI: 10.1007/BF00442021  0.349
1988 Negus SS, Dykstra LA. Kappa antagonist properties of buprenorphine in the shock titration procedure. European Journal of Pharmacology. 156: 77-86. PMID 2850212 DOI: 10.1016/0014-2999(88)90149-5  0.34
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