Stuart J. Conway, PhD - Publications

Affiliations: 
2003-2005 School fo Chemistry University of St Andrews, Saint Andrews, Scotland, United Kingdom 
 2008- Department of Chemistry University of Oxford, Oxford, United Kingdom 
Area:
Chemical biology, organic chemistry

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Troelsen KS, Calder EDD, Skwarska A, Sneddon D, Hammond EM, Conway SJ. Zap-Pano: a Photocaged pro-drug of the KDAC inhibitor panobinostat. Chemmedchem. PMID 34259396 DOI: 10.1002/cmdc.202100403  1
2021 Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, ... ... Conway SJ, et al. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of Medicinal Chemistry. PMID 34255515 DOI: 10.1021/acs.jmedchem.1c00348  1
2021 Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, ... ... Conway SJ, et al. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of Medicinal Chemistry. PMID 34255515 DOI: 10.1021/acs.jmedchem.1c00348  1
2021 Flynn NR, Ward MD, Schleiff MA, Laurin CMC, Farmer R, Conway SJ, Boysen G, Swamidass SJ, Miller GP. Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors. Metabolites. 11. PMID 34203690 DOI: 10.3390/metabo11060390  0.32
2021 Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, et al. Publisher Correction: Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications. Nature Chemistry. PMID 34103693 DOI: 10.1038/s41557-021-00742-x  0.48
2021 Skwarska A, Calder EDD, Sneddon D, Bolland H, Odyniec ML, Mistry IN, Martin J, Folkes LK, Conway SJ, Hammond EM. Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor. Cell Chemical Biology. PMID 33910023 DOI: 10.1016/j.chembiol.2021.04.004  1
2021 Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, et al. Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications. Nature Chemistry. PMID 33833446 DOI: 10.1038/s41557-021-00660-y  0.48
2020 Bassi G, Favalli N, Vuk M, Catalano M, Martinelli A, Trenner A, Porro A, Yang S, Tham CL, Moroglu M, Yue WW, Conway SJ, Vogt PK, Sartori AA, Scheuermann J, et al. A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2001970. PMID 33240760 DOI: 10.1002/advs.202001970  0.48
2020 Laurin CMC, Bluck JP, Chan AKN, Keller M, Boczek A, Scorah AR, See KFL, Jennings LE, Hewings DS, Woodhouse F, Reynolds JK, Schiedel M, Humphreys PG, Biggin PC, Conway SJ. Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of . Acs Infectious Diseases. PMID 33203208 DOI: 10.1021/acsinfecdis.0c00618  1
2020 Bowler E, Skwarska A, Wilson JD, Ramachandran S, Bolland H, Easton A, Ostheimer C, Hwang MS, Leszczynska KB, Conway SJ, Hammond EM. Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism. Iscience. 23: 101668. PMID 33134898 DOI: 10.1016/j.isci.2020.101668  1
2020 Conway SJ, Arimondo P, Arrowsmith C, Jin J, Luo C, Meanwell N, Young W, Georg G, Wang S. Epigenetics 2.0: Special Issue on Epigenetics-Call for Papers. Journal of Medicinal Chemistry. PMID 33090784 DOI: 10.1021/acs.jmedchem.0c01748  1
2020 Catalano M, Moroglu M, Balbi P, Mazzieri F, Clayton J, Andrews KH, Bigatti M, Scheuermann J, Conway SJ, Neri D. Selective fragments for the CREBBP bromodomain identified from an Encoded Self-Assembly Chemical Library. Chemmedchem. PMID 32686307 DOI: 10.1002/Cmdc.202000528  0.48
2019 Geddes BA, Paramasivan P, Joffrin A, Thompson AL, Christensen K, Jorrin B, Brett P, Conway SJ, Oldroyd GED, Poole PS. Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria. Nature Communications. 10: 3430. PMID 31366919 DOI: 10.1038/S41467-019-10882-X  1
2019 Rasmussen T, Rasmussen A, Yang L, Kaul C, Black S, Galbiati H, Conway SJ, Miller S, Blount P, Booth IR. Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets. Journal of Molecular Biology. PMID 31173776 DOI: 10.1016/J.Jmb.2019.05.043  1
2019 Schiedel M, Moroglu M, Ascough DMH, Chamberlain AER, Kamps JJAG, Sekirnik AR, Conway SJ. Chemical epigenetics: the impact of chemical- and chemical biology techniques on bromodomain target validation. Angewandte Chemie (International Ed. in English). PMID 30633431 DOI: 10.1002/Anie.201812164  0.96
2018 Collins SL, Saha J, Bouchez LC, Hammond EM, Conway SJ. Hypoxia-activated small molecule-induced gene expression. Acs Chemical Biology. PMID 30451487 DOI: 10.1021/Acschembio.8B00858  1
2018 Schiedel M, Conway SJ. Small molecules as tools to study the chemical epigenetics of lysine acetylation. Current Opinion in Chemical Biology. 45: 166-178. PMID 29958150 DOI: 10.1016/J.Cbpa.2018.06.015  0.96
2018 Phillips JO, Butt LE, Henderson CA, Devonshire M, Healy J, Conway SJ, Locker N, Pickford AR, Vincent HA, Callaghan AJ. High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions. Nucleic Acids Research. PMID 29846708 DOI: 10.1093/Nar/Gky410  1
2018 Jennings LE, Schiedel M, Hewings DS, Picaud S, Laurin CMC, Bruno PA, Bluck JP, Scorah AR, See L, Reynolds JK, Moroglu M, Mistry IN, Hicks A, Guzanov P, Clayton J, ... ... Conway SJ, et al. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. Bioorganic & Medicinal Chemistry. PMID 29776834 DOI: 10.1016/J.Bmc.2018.05.003  1
2017 Mistry IN, Thomas M, Calder EDD, Conway SJ, Hammond EM. Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics. 98: 1183-1196. PMID 28721903 DOI: 10.1016/J.Ijrobp.2017.03.024  1
2017 Pliotas C, Grayer SC, Ekkerman S, Chan AK, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JL, Paton RS, Claridge TDW, Miller S, ... ... Conway SJ, et al. AMP binding stabilizes the KTN domain of the Shewanella denitrificans Kef potassium efflux system. Biochemistry. PMID 28656748 DOI: 10.1021/Acs.Biochem.7B00300  1
2017 O'Connor LJ, Mistry IN, Collins SL, Folkes LK, Brown G, Conway SJ, Hammond EM. CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes. Acs Central Science. 3: 20-30. PMID 28149949 DOI: 10.1021/Acscentsci.6B00276  1
2016 Costa KC, Glasser NR, Conway SJ, Newman DK. Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms. Science (New York, N.Y.). PMID 27940577 DOI: 10.1126/Science.Aag3180  1
2016 Sekirnik Née Measures AR, Hewings DS, Theodoulou NH, Jursins L, Lewendon KR, Jennings LE, Rooney TP, Heightman TD, Conway SJ. Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3. Angewandte Chemie (International Ed. in English). PMID 27264992 DOI: 10.1002/Anie.201602908  1
2016 Healy J, Rasmussen T, Miller S, Booth IR, Conway SJ. The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef. Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry. 3: 439-446. PMID 27110363 DOI: 10.1039/C5Qo00436E  1
2016 O'Connor LJ, Cazares-Körner C, Saha J, Evans CN, Stratford MR, Hammond EM, Conway SJ. Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs. Nature Protocols. 11: 781-94. PMID 27010756 DOI: 10.1038/Nprot.2016.034  1
2016 Conway SJ, Woster PM, Greenlee WJ, Georg G, Wang S. Epigenetics: Novel Therapeutics Targeting Epigenetics. Journal of Medicinal Chemistry. PMID 26824165 DOI: 10.1021/Acs.Jmedchem.6B00098  1
2016 Brand M, Measures AR, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Correction to Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions. Acs Chemical Biology. PMID 26756254 DOI: 10.1021/Acschembio.5B01065  1
2015 Wu CH, Kong L, Bialecka-Fornal M, Park S, Thompson AL, Kulkarni G, Conway SJ, Newman DK. Quantitative hopanoid analysis enables robust pattern detection and comparison between laboratories. Geobiology. 13: 391-407. PMID 25865768 DOI: 10.1111/Gbi.12132  1
2015 Brand M, Measures AM, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Small molecule inhibitors of bromodomain-acetyl-lysine interactions. Acs Chemical Biology. 10: 22-39. PMID 25549280 DOI: 10.1021/Cb500996U  1
2015 Conway SJ, Woster PM, Shen JK, Georg G, Wang S. Epigenetics: novel therapeutics targeting epigenetics. Journal of Medicinal Chemistry. 58: 523-4. PMID 25532017 DOI: 10.1021/jm501941q  1
2015 Gregory M, Yin MX, McConville MJ, Williams E, Bullock AN, Conway SJ, Burgess AW, Catimel B, Holmes AB. Synthesis of highly water-soluble adamantyl phosphoinositide derivatives Australian Journal of Chemistry. 68: 543-548. DOI: 10.1071/Ch14543  1
2015 O'Connor LJ, Cazares-Körner C, Saha J, Evans CNG, Stratford MRL, Hammond EM, Conway SJ. Efficient synthesis of 2-nitroimidazole derivatives and the bioreductive clinical candidate Evofosfamide (TH-302) Organic Chemistry Frontiers. 2: 1026-1029. DOI: 10.1039/C5Qo00211G  1
2015 Hewings DS, Rooney TPC, Conway SJ. Emerging Epigenetic Therapies-Bromodomain Ligands Epigenetic Cancer Therapy. 495-524. DOI: 10.1016/B978-0-12-800206-3.00022-7  1
2014 Hay DA, Fedorov O, Martin S, Singleton DC, Tallant C, Wells C, Picaud S, Philpott M, Monteiro OP, Rogers CM, Conway SJ, Rooney TP, Tumber A, Yapp C, Filippakopoulos P, et al. Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains. Journal of the American Chemical Society. 136: 9308-19. PMID 24946055 DOI: 10.1021/Ja412434F  1
2014 Rooney TP, Filippakopoulos P, Fedorov O, Picaud S, Cortopassi WA, Hay DA, Martin S, Tumber A, Rogers CM, Philpott M, Wang M, Thompson AL, Heightman TD, Pryde DC, Cook A, ... ... Conway SJ, et al. A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction. Angewandte Chemie (International Ed. in English). 53: 6126-30. PMID 24821300 DOI: 10.1002/Anie.201402750  1
2014 Healy J, Ekkerman S, Pliotas C, Richard M, Bartlett W, Grayer SC, Morris GM, Miller S, Booth IR, Conway SJ, Rasmussen T. Understanding the structural requirements for activators of the Kef bacterial potassium efflux system. Biochemistry. 53: 1982-92. PMID 24601535 DOI: 10.1021/Bi5001118  1
2014 Jennings LE, Measures AR, Wilson BG, Conway SJ. Phenotypic screening and fragment-based approaches to the discovery of small-molecule bromodomain ligands. Future Medicinal Chemistry. 6: 179-204. PMID 24467243 DOI: 10.4155/Fmc.13.197  1
2013 Hay D, Fedorov O, Filippakopoulos P, Martin S, Philpott M, Picaud S, Hewings DS, Uttakar S, Heightman TD, Conway SJ, Knapp S, Brennan PE. The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains. Medchemcomm. 4: 140-144. PMID 26682033 DOI: 10.1039/C2Md20189E  1
2013 Zhao Y, Wang S, Sorenson CM, Teixeira L, Dubielzig RR, Peters DM, Conway SJ, Jefcoate CR, Sheibani N. Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. Molecular and Cellular Biology. 33: 4225-40. PMID 23979599 DOI: 10.1128/Mcb.00856-13  1
2013 Cazares-Körner C, Pires IM, Swallow ID, Grayer SC, O'Connor LJ, Olcina MM, Christlieb M, Conway SJ, Hammond EM. CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A. Acs Chemical Biology. 8: 1451-9. PMID 23597309 DOI: 10.1021/cb4001537  1
2013 Hewings DS, Fedorov O, Filippakopoulos P, Martin S, Picaud S, Tumber A, Wells C, Olcina MM, Freeman K, Gill A, Ritchie AJ, Sheppard DW, Russell AJ, Hammond EM, Knapp S, ... ... Conway SJ, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. Journal of Medicinal Chemistry. 56: 3217-27. PMID 23517011 DOI: 10.1021/Jm301588R  1
2013 Conway SJ. Bürgenstock 2012: Reflections on stereochemistry. Nature Chemistry. 5: 86-8. PMID 23344442 DOI: 10.1038/Nchem.1552  1
2013 Hay D, Fedorov O, Filippakopoulos P, Martin S, Philpott M, Picaud S, Hewings DS, Uttakar S, Heightman TD, Conway SJ, Knapp S, Brennan PE. The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains Medchemcomm. 4: 140-144. DOI: 10.1039/c2md20189e  1
2012 Conway SJ. Bromodomains: are readers right for epigenetic therapy? Acs Medicinal Chemistry Letters. 3: 691-4. PMID 24900532 DOI: 10.1021/Ml300221T  1
2012 Davis LC, Morgan AJ, Chen JL, Snead CM, Bloor-Young D, Shenderov E, Stanton-Humphreys MN, Conway SJ, Churchill GC, Parrington J, Cerundolo V, Galione A. NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing. Current Biology : Cb. 22: 2331-7. PMID 23177477 DOI: 10.1016/J.Cub.2012.10.035  1
2012 Hewings DS, Rooney TP, Jennings LE, Hay DA, Schofield CJ, Brennan PE, Knapp S, Conway SJ. Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions. Journal of Medicinal Chemistry. 55: 9393-413. PMID 22924434 DOI: 10.1021/Jm300915B  1
2012 Stanton-Humphreys MN, Taylor RD, McDougall C, Hart ML, Brown CT, Emptage NJ, Conway SJ. Wavelength-orthogonal photolysis of neurotransmitters in vitro. Chemical Communications (Cambridge, England). 48: 657-9. PMID 21980596 DOI: 10.1039/C1Cc15135E  1
2012 Elliott TS, Slowey A, Ye Y, Conway SJ. The use of phosphate bioisosteres in medicinal chemistry and chemical biology Medchemcomm. 3: 735-751. DOI: 10.1039/C2Md20079A  1
2011 Wu X, Chen S, He Y, Rhodes SD, Mohammad KS, Li X, Yang X, Jiang L, Nalepa G, Snider P, Robling AG, Clapp DW, Conway SJ, Guise TA, Yang FC. The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. Plos One. 6: e24917. PMID 21980365 DOI: 10.1371/journal.pone.0024917  1
2011 Hewings DS, Wang M, Philpott M, Fedorov O, Uttarkar S, Filippakopoulos P, Picaud S, Vuppusetty C, Marsden B, Knapp S, Conway SJ, Heightman TD. 3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands. Journal of Medicinal Chemistry. 54: 6761-70. PMID 21851057 DOI: 10.1021/Jm200640V  1
2011 Borger E, Aitken L, Muirhead KE, Allen ZE, Ainge JA, Conway SJ, Gunn-Moore FJ. Mitochondrial β-amyloid in Alzheimer's disease. Biochemical Society Transactions. 39: 868-73. PMID 21787315 DOI: 10.1042/Bst0390868  1
2011 Lyngberg L, Healy J, Bartlett W, Miller S, Conway SJ, Booth IR, Rasmussen T. KefF, the regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity. Journal of Bacteriology. 193: 4925-32. PMID 21742892 DOI: 10.1128/Jb.05272-11  1
2011 Keddie NS, Ye Y, Aslam T, Luyten T, Bello D, Garnham C, Bultynck G, Galione A, Conway SJ. Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor. Chemical Communications (Cambridge, England). 47: 242-4. PMID 20938532 DOI: 10.1039/C0Cc03003A  1
2010 Roosild TP, Castronovo S, Healy J, Miller S, Pliotas C, Rasmussen T, Bartlett W, Conway SJ, Booth IR. Mechanism of ligand-gated potassium efflux in bacterial pathogens. Proceedings of the National Academy of Sciences of the United States of America. 107: 19784-9. PMID 21041667 DOI: 10.1073/Pnas.1012716107  1
2010 Muirhead KE, Froemming M, Li X, Musilek K, Conway SJ, Sames D, Gunn-Moore FJ. (-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells. Acs Chemical Biology. 5: 1105-14. PMID 20836522 DOI: 10.1021/Cb100199M  1
2010 Muirhead KE, Borger E, Aitken L, Conway SJ, Gunn-Moore FJ. The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease. The Biochemical Journal. 426: 255-70. PMID 20175748 DOI: 10.1042/Bj20091941  1
2010 Conway SJ, Gardiner J, Grove SJ, Johns MK, Lim ZY, Painter GF, Robinson DE, Schieber C, Thuring JW, Wong LS, Yin MX, Burgess AW, Catimel B, Hawkins PT, Ktistakis NT, et al. Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes. Organic & Biomolecular Chemistry. 8: 66-76. PMID 20024134 DOI: 10.1039/B913399B  1
2009 Van Ryssen MP, Avlonitis N, Giniatullin R, McDougall C, Carr JL, Stanton-Humphreys MN, Borgström EL, Brown CT, Fayuk D, Surin A, Niittykoski M, Khiroug L, Conway SJ. Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. Organic & Biomolecular Chemistry. 7: 4695-707. PMID 19865707 DOI: 10.1039/B914981C  1
2009 Johns MK, Yin MX, Conway SJ, Robinson DE, Wong LS, Bamert R, Wettenhall RE, Holmes AB. Synthesis and biological evaluation of a novel cardiolipin affinity matrix. Organic & Biomolecular Chemistry. 7: 3691-7. PMID 19707673 DOI: 10.1039/B909306K  1
2009 Harzheim D, Movassagh M, Foo RS, Ritter O, Tashfeen A, Conway SJ, Bootman MD, Roderick HL. Increased InsP3Rs in the junctional sarcoplasmic reticulum augment Ca2+ transients and arrhythmias associated with cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 106: 11406-11. PMID 19549843 DOI: 10.1073/Pnas.0905485106  1
2009 Avlonitis N, Chalmers S, McDougall C, Stanton-Humphreys MN, Brown CT, McCarron JG, Conway SJ. Caged AG10: new tools for spatially predefined mitochondrial uncoupling. Molecular Biosystems. 5: 450-7. PMID 19381360 DOI: 10.1039/B820415M  1
2009 Florence GJ, Aslam T, Miller GJ, Milne GDS, Conway SJ. Thieme chemistry journal awardees - where are they now? synthesis of the marine glycolipid dioctadecanoyl discoside Synlett. 3099-3102. DOI: 10.1055/S-0029-1218301  1
2009 Elliott TS, Nemeth J, Swain SA, Conway SJ. A synthesis of dioctanoyl phosphatidylinositol Tetrahedron Asymmetry. 20: 2809-2813. DOI: 10.1016/J.Tetasy.2009.11.026  1
2009 Keddie NS, Bultynck G, Luyten T, Slawin AMZ, Conway SJ. A type 2 Ferrier rearrangement-based synthesis of d-myo-inositol 1,4,5-trisphosphate Tetrahedron Asymmetry. 20: 857-866. DOI: 10.1016/J.Tetasy.2009.03.006  1
2008 Conway SJ. TRPing the switch on pain: an introduction to the chemistry and biology of capsaicin and TRPV1. Chemical Society Reviews. 37: 1530-45. PMID 18648679 DOI: 10.1039/B610226N  1
2008 Murray RG, Whitehead DM, Le Strat F, Conway SJ. Facile one-pot synthesis of 5-substituted hydantoins. Organic & Biomolecular Chemistry. 6: 988-91. PMID 18327322 DOI: 10.1039/B719675J  1
2008 Murray RG, Whitehead DM, Strat FL, Conway SJ. Gallium(III) Triflate Catalyzed Conversion of Aldehydes and Ketones to Hydantoins Synfacts. 2008: 570-570. DOI: 10.1055/S-2008-1067072  1
2007 Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, et al. The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity. 27: 268-80. PMID 17692540 DOI: 10.1016/J.Immuni.2007.05.023  1
2007 Conway SJ, Miller GJ. Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives. Natural Product Reports. 24: 687-707. PMID 17653355 DOI: 10.1039/B407701F  1
2007 Bello D, Aslam T, Bultynck G, Slawin AM, Roderick HL, Bootman MD, Conway SJ. Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate. The Journal of Organic Chemistry. 72: 5647-59. PMID 17585817 DOI: 10.1021/Jo070611A  1
2007 Bootman MD, Harzheim D, Smyrnias I, Conway SJ, Roderick HL. Temporal changes in atrial EC-coupling during prolonged stimulation with endothelin-1. Cell Calcium. 42: 489-501. PMID 17574672 DOI: 10.1016/J.Ceca.2007.05.004  1
2007 Wu J, Holstein JD, Upadhyay G, Lin DT, Conway S, Muller E, Lechleiter JD. Purinergic receptor-stimulated IP3-mediated Ca2+ release enhances neuroprotection by increasing astrocyte mitochondrial metabolism during aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6510-20. PMID 17567812 DOI: 10.1523/Jneurosci.1256-07.2007  1
2007 McNeill E, Conway SJ, Roderick HL, Bootman MD, Hogg N. Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils. Cell Calcium. 41: 107-21. PMID 16814379 DOI: 10.1016/J.Ceca.2006.05.004  1
2006 Proven A, Roderick HL, Conway SJ, Berridge MJ, Horton JK, Capper SJ, Bootman MD. Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes. Journal of Cell Science. 119: 3363-75. PMID 16882691 DOI: 10.1242/Jcs.03073  1
2006 Carr JL, Wease KN, Van Ryssen MP, Paterson S, Agate B, Gallagher KA, Brown CT, Scott RH, Conway SJ. In vitro photo-release of a TRPV1 agonist. Bioorganic & Medicinal Chemistry Letters. 16: 208-12. PMID 16213723 DOI: 10.1016/J.Bmcl.2005.09.018  1
2006 Conway SJ, Thuring JW, Andreu S, Kvinlaug BT, Roderick HL, Bootman MD, Holmes AB. The synthesis of membrane permeant derivatives of myo-inositol 1,4,5-trisphosphate Australian Journal of Chemistry. 59: 887-893. DOI: 10.1071/Ch06357  1
2004 Mackenzie L, Roderick HL, Proven A, Conway SJ, Bootman MD. Inositol 1,4,5-trisphosphate receptors in the heart. Biological Research. 37: 553-7. PMID 15709681 DOI: 10.4067/S0716-97602004000400008  1
2004 Mackenzie L, Roderick HL, Berridge MJ, Conway SJ, Bootman MD. The spatial pattern of atrial cardiomyocyte calcium signalling modulates contraction. Journal of Cell Science. 117: 6327-37. PMID 15561771 DOI: 10.1242/Jcs.01559  1
2004 Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. The Journal of Cell Biology. 166: 193-203. PMID 15263017 DOI: 10.1083/Jcb.200309146  1
2004 Kasri NN, Holmes AM, Bultynck G, Parys JB, Bootman MD, Rietdorf K, Missiaen L, McDonald F, De Smedt H, Conway SJ, Holmes AB, Berridge MJ, Roderick HL. Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins. The Embo Journal. 23: 312-21. PMID 14685260 DOI: 10.1038/Sj.Emboj.7600037  1
2004 Billington RA, Thuring JW, Conway SJ, Packman L, Holmes AB, Genazzani AA. Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate). The Biochemical Journal. 378: 275-80. PMID 14606955 DOI: 10.1042/Bj20031284  1
2003 Miller JC, Howson PA, Conway SJ, Williams RV, Clark BP, Jane DE. Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. British Journal of Pharmacology. 139: 1523-31. PMID 12922940 DOI: 10.1038/Sj.Bjp.0705377  1
2003 Samways DS, Li WH, Conway SJ, Holmes AB, Bootman MD, Henderson G. Co-incident signalling between mu-opioid and M3 muscarinic receptors at the level of Ca2+ release from intracellular stores: lack of evidence for Ins(1,4,5)P3 receptor sensitization. The Biochemical Journal. 375: 713-20. PMID 12880387 DOI: 10.1042/Bj20030508  1
2003 Peppiatt CM, Collins TJ, Mackenzie L, Conway SJ, Holmes AB, Bootman MD, Berridge MJ, Seo JT, Roderick HL. 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels. Cell Calcium. 34: 97-108. PMID 12767897 DOI: 10.1016/S0143-4160(03)00026-5  1
2002 Johenning FW, Zochowski M, Conway SJ, Holmes AB, Koulen P, Ehrlich BE. Distinct intracellular calcium transients in neurites and somata integrate neuronal signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5344-53. PMID 12097486 DOI: 10.1523/Jneurosci.22-13-05344.2002  1
2002 Conway SJ, Miller JC, Bond AD, Clarkc BP, Jane DE. Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4 Journal of the Chemical Society. Perkin Transactions 1. 1625-1627. DOI: 10.1039/B204891D  1
2001 Conway SJ, Miller JC, Howson PA, Clark BP, Jane DE. Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors. Bioorganic & Medicinal Chemistry Letters. 11: 777-80. PMID 11277518 DOI: 10.1016/S0960-894X(01)00052-X  1
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