Jared Goldstone - Publications

Woods Hole Oceanographic Institution, Falmouth, MA, United States 
environmental toxicology; molecular evolution; comparative genomics

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Goldstone JV, Lamb DC, Kelly SL, Lepesheva GI, Stegeman JJ. Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s. Journal of Inorganic Biochemistry. 245: 112241. PMID 37209461 DOI: 10.1016/j.jinorgbio.2023.112241  0.525
2022 Lamb DC, Goldstone JV, Zhao B, Lei L, Mullins JGL, Allen MJ, Kelly SL, Stegeman JJ. Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity. Biomolecules. 12. PMID 36009001 DOI: 10.3390/biom12081107  0.489
2022 Brahim Belhaouari D, Pires De Souza GA, Lamb DC, Kelly SL, Goldstone JV, Stegeman JJ, Colson P, La Scola B, Aherfi S. Metabolic arsenal of giant viruses: Host hijack or self-use? Elife. 11. PMID 35801640 DOI: 10.7554/eLife.78674  0.502
2021 Brun NR, Salanga MC, Mora-Zamorano FX, Lamb DC, Goldstone JV, Stegeman JJ. Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish. Scientific Reports. 11: 23892. PMID 34903767 DOI: 10.1038/s41598-021-03068-3  0.754
2021 Brun NR, Panlilio JM, Zhang K, Zhao Y, Ivashkin E, Stegeman JJ, Goldstone JV. Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish. Communications Biology. 4: 1129. PMID 34561524 DOI: 10.1038/s42003-021-02626-9  0.734
2021 Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A. The chemical defensome of five model teleost fish. Scientific Reports. 11: 10546. PMID 34006915 DOI: 10.1038/s41598-021-89948-0  0.563
2021 Pankov KV, McArthur AG, Gold DA, Nelson DR, Goldstone JV, Wilson JY. The cytochrome P450 (CYP) superfamily in cnidarians. Scientific Reports. 11: 9834. PMID 33972594 DOI: 10.1038/s41598-021-88700-y  0.637
2021 Celander MC, Goldstone JV, Brun NR, Clark B, Jayaraman S, Nacci D, Stegeman JJ. Resistance to Cyp3a induction by polychlorinated biphenyls, including non-dioxin-like PCB153, in gills of killifish (Fundulus heteroclitus) from New Bedford Harbor. Environmental Toxicology and Pharmacology. 103580. PMID 33429071 DOI: 10.1016/j.etap.2020.103580  0.742
2020 Lamb DC, Hargrove TY, Zhao B, Wawrzak Z, Goldstone JV, Nes WD, Kelly SL, Waterman MR, Stegeman JJ, Lepesheva GI. Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases. Molecular Biology and Evolution. PMID 33031537 DOI: 10.1093/molbev/msaa260  0.502
2019 Salanga MC, Brun NR, Francolini RD, Stegeman JJ, Goldstone JV. CRISPR-Cas9 mutated pregnane x receptor (pxr) retains pregnenolone-induced expression of cyp3a65 in zebrafish (Danio rerio) larvae. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31868891 DOI: 10.1093/Toxsci/Kfz246  0.756
2019 Lamb DC, Follmer AH, Goldstone JV, Nelson DR, Warrilow AG, Price CL, True MY, Kelly SL, Poulos TL, Stegeman JJ. On the occurrence of cytochrome P450 in viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 31167942 DOI: 10.1073/Pnas.1901080116  0.518
2018 Lille-Langøy R, Karlsen OA, Myklebust LM, Goldstone JV, Mork-Jansson A, Male R, Blumberg B, Stegeman JJ, Goksøyr A. Sequence variations in pxr (nr1i2) from zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30371853 DOI: 10.1093/Toxsci/Kfy269  0.557
2018 Ulin A, Henderson J, Pham MT, Meyo J, Chen Y, Karchner SI, Goldstone JV, Hahn ME, Williams LM. Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in zebrafish (Danio rerio). Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30321412 DOI: 10.1093/Toxsci/Kfy257  0.314
2018 Eide M, Rydbeck H, Tørresen OK, Lille-Langøy R, Puntervoll P, Goldstone JV, Jakobsen KS, Stegeman J, Goksøyr A, Karlsen OA. Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 8: 10404. PMID 29991818 DOI: 10.1038/S41598-018-28498-4  0.579
2017 Holland EB, Goldstone JV, Pessah IN, Whitehead A, Reid NM, Karchner SI, Hahn ME, Nacci DE, Clark BW, Stegeman JJ. Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison. Aquatic Toxicology (Amsterdam, Netherlands). 192: 105-115. PMID 28942070 DOI: 10.1016/J.Aquatox.2017.09.002  0.56
2017 Lemaire B, Karchner SI, Goldstone JV, Lamb DC, Drazen JC, Rees JF, Hahn ME, Stegeman JJ. Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus. Biochimica Et Biophysica Acta. PMID 28694077 DOI: 10.1016/J.Bbapap.2017.06.026  0.518
2017 Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A. The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo. Redox Biology. 13: 207-218. PMID 28582729 DOI: 10.1016/J.Redox.2017.05.023  0.467
2016 Jansson E, Mattsson A, Goldstone J, Berg C. Sex-dependent expression of anti-Müllerian hormone (amh) and amh receptor 2 during sex organ differentiation and characterization of the Müllerian duct development in Xenopus tropicalis. General and Comparative Endocrinology. 229: 132-144. PMID 26987287 DOI: 10.1016/J.Ygcen.2016.03.018  0.34
2016 Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ. Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. Toxicology and Applied Pharmacology. PMID 26853319 DOI: 10.1016/J.Taap.2016.02.001  0.594
2015 Goldstone JV, Sundaramoorthy M, Zhao B, Waterman MR, Stegeman JJ, Lamb DC. Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution. Molecular Phylogenetics and Evolution. PMID 26432395 DOI: 10.1016/J.Ympev.2015.09.012  0.572
2015 Stegeman JJ, Behrendt L, Woodin BR, Kubota A, Lemaire B, Pompon D, Goldstone JV, Urban P. Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast. Biochimica Et Biophysica Acta. 1850: 2340-52. PMID 26231923 DOI: 10.1016/J.Bbagen.2015.07.010  0.574
2015 Lille-Langøy R, Goldstone JV, Rusten M, Milnes MR, Male R, Stegeman JJ, Blumberg B, Goksøyr A. Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. Toxicology and Applied Pharmacology. 284: 54-64. PMID 25680588 DOI: 10.1016/J.Taap.2015.02.001  0.453
2015 Fritsch EB, Stegeman JJ, Goldstone JV, Nacci DE, Champlin D, Jayaraman S, Connon RE, Pessah IN. Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA. Aquatic Toxicology (Amsterdam, Netherlands). 159: 156-66. PMID 25546006 DOI: 10.1016/J.Aquatox.2014.12.017  0.495
2015 Kubota A, Goldstone JV, Lemaire B, Takata M, Woodin BR, Stegeman JJ. Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish. Toxicological Sciences : An Official Journal of the Society of Toxicology. 143: 398-407. PMID 25424564 DOI: 10.1093/Toxsci/Kfu240  0.575
2014 Morrison AM, Goldstone JV, Lamb DC, Kubota A, Lemaire B, Stegeman JJ. Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase. Biochimica Et Biophysica Acta. 1840: 1825-36. PMID 24361620 DOI: 10.1016/J.Bbagen.2013.12.009  0.5
2013 Williams LM, Timme-Laragy AR, Goldstone JV, McArthur AG, Stegeman JJ, Smolowitz RM, Hahn ME. Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio. Plos One. 8: e79574. PMID 24298298 DOI: 10.1371/Journal.Pone.0079574  0.547
2013 Bainy AC, Kubota A, Goldstone JV, Lille-Langøy R, Karchner SI, Celander MC, Hahn ME, Goksøyr A, Stegeman JJ. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio). Aquatic Toxicology (Amsterdam, Netherlands). 142: 447-57. PMID 24121122 DOI: 10.1016/J.Aquatox.2013.09.014  0.554
2013 Timme-Laragy AR, Goldstone JV, Imhoff BR, Stegeman JJ, Hahn ME, Hansen JM. Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo. Free Radical Biology & Medicine. 65: 89-101. PMID 23770340 DOI: 10.1016/J.Freeradbiomed.2013.06.011  0.497
2013 Kubota A, Bainy AC, Woodin BR, Goldstone JV, Stegeman JJ. The cytochrome P450 2AA gene cluster in zebrafish (Danio rerio): expression of CYP2AA1 and CYP2AA2 and response to phenobarbital-type inducers. Toxicology and Applied Pharmacology. 272: 172-9. PMID 23726801 DOI: 10.1016/J.Taap.2013.05.017  0.578
2013 Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, ... ... Goldstone JV, et al. The African coelacanth genome provides insights into tetrapod evolution. Nature. 496: 311-6. PMID 23598338 DOI: 10.1038/Nature12027  0.521
2013 Nelson DR, Goldstone JV, Stegeman JJ. The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120474. PMID 23297357 DOI: 10.1098/Rstb.2012.0474  0.545
2013 Zanette J, Jenny MJ, Goldstone JV, Parente T, Woodin BR, Bainy AC, Stegeman JJ. Identification and expression of multiple CYP1-like and CYP3-like genes in the bivalve mollusk Mytilus edulis. Aquatic Toxicology (Amsterdam, Netherlands). 128: 101-12. PMID 23277104 DOI: 10.1016/J.Aquatox.2012.11.017  0.575
2012 Goldstone JV, Stegeman JJ. Methodological approaches to cytochrome P450 profiling in embryos. Methods in Molecular Biology (Clifton, N.J.). 889: 265-75. PMID 22669670 DOI: 10.1007/978-1-61779-867-2_16  0.555
2012 Goldstone HM, Tokunaga S, Schlezinger JJ, Goldstone JV, Stegeman JJ. EZR1: a novel family of highly expressed retroelements induced by TCDD and regulated by a NF-κB-like factor in embryos of zebrafish (Danio rerio). Zebrafish. 9: 15-25. PMID 22356696 DOI: 10.1089/Zeb.2011.0722  0.699
2012 Timme-Laragy AR, Karchner SI, Franks DG, Jenny MJ, Harbeitner RC, Goldstone JV, McArthur AG, Hahn ME. Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2). The Journal of Biological Chemistry. 287: 4609-27. PMID 22174413 DOI: 10.1074/jbc.M111.260125  0.353
2012 Stegeman J, Goldstone J, Jonsson M, Kubota A, Lemaire B. Evolutionary history and functional diversity of the cytochrome P450 1 gene family Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 163: S28. DOI: 10.1016/j.cbpa.2012.05.084  0.515
2011 Parente TE, Rebelo MF, da-Silva ML, Woodin BR, Goldstone JV, Bisch PM, Paumgartten FJ, Stegeman JJ. Structural features of cytochrome P450 1A associated with the absence of EROD activity in liver of the loricariid catfish Pterygoplichthys sp. Gene. 489: 111-8. PMID 21840383 DOI: 10.1016/J.Gene.2011.07.023  0.526
2011 Shrestha B, Reed JM, Starks PT, Kaufman GE, Goldstone JV, Roelke ME, O'Brien SJ, Koepfli KP, Frank LG, Court MH. Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivory. Plos One. 6: e18046. PMID 21464924 DOI: 10.1371/Journal.Pone.0018046  0.317
2011 Gao K, Brandt I, Goldstone JV, Jönsson ME. Cytochrome P450 1A, 1B, and 1C mRNA induction patterns in three-spined stickleback exposed to a transient and a persistent inducer. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 154: 42-55. PMID 21354474 DOI: 10.1016/j.cbpc.2011.02.005  0.345
2011 Kubota A, Stegeman JJ, Goldstone JV, Nelson DR, Kim EY, Tanabe S, Iwata H. Cytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expression. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 153: 280-9. PMID 21130899 DOI: 10.1016/J.Cbpc.2010.11.006  0.61
2011 Jönsson ME, Berg C, Goldstone JV, Stegeman JJ. New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development. Toxicology and Applied Pharmacology. 250: 170-83. PMID 20965207 DOI: 10.1016/J.Taap.2010.10.010  0.597
2010 Goldstone JV, McArthur AG, Kubota A, Zanette J, Parente T, Jönsson ME, Nelson DR, Stegeman JJ. Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish. Bmc Genomics. 11: 643. PMID 21087487 DOI: 10.1186/1471-2164-11-643  0.587
2010 Jönsson ME, Gao K, Olsson JA, Goldstone JV, Brandt I. Induction patterns of new CYP1 genes in environmentally exposed rainbow trout. Aquatic Toxicology (Amsterdam, Netherlands). 98: 311-21. PMID 20371123 DOI: 10.1016/j.aquatox.2010.03.003  0.376
2010 Behrendt L, Jönsson ME, Goldstone JV, Stegeman JJ. Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation. Aquatic Toxicology (Amsterdam, Netherlands). 98: 74-82. PMID 20189255 DOI: 10.1016/J.Aquatox.2010.01.008  0.508
2010 Zanette J, Goldstone JV, Bainy AC, Stegeman JJ. Identification of CYP genes in Mytilus (mussel) and Crassostrea (oyster) species: first approach to the full complement of cytochrome P450 genes in bivalves. Marine Environmental Research. 69: S1-3. PMID 19926125 DOI: 10.1016/J.Marenvres.2009.10.013  0.578
2009 Zanette J, Jenny MJ, Goldstone JV, Woodin BR, Watka LA, Bainy AC, Stegeman JJ. New cytochrome P450 1B1, 1C2 and 1D1 genes in the killifish Fundulus heteroclitus: Basal expression and response of five killifish CYP1s to the AHR agonist PCB126. Aquatic Toxicology (Amsterdam, Netherlands). 93: 234-43. PMID 19515436 DOI: 10.1016/J.Aquatox.2009.05.008  0.582
2009 Goldstone JV, Jönsson ME, Behrendt L, Woodin BR, Jenny MJ, Nelson DR, Stegeman JJ. Cytochrome P450 1D1: a novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD. Archives of Biochemistry and Biophysics. 482: 7-16. PMID 19103147 DOI: 10.1016/J.Abb.2008.12.002  0.601
2008 Goldstone JV. Environmental sensing and response genes in cnidaria: the chemical defensome in the sea anemone Nematostella vectensis. Cell Biology and Toxicology. 24: 483-502. PMID 18956243 DOI: 10.1007/s10565-008-9107-5  0.315
2008 Goldstone JV, Stegeman JJ. Gene structure of the novel cytochrome P4501D1 genes in stickleback (Gasterosteus aculeatus) and medaka (Oryzias latipes). Marine Environmental Research. 66: 19-20. PMID 18400289 DOI: 10.1016/J.Marenvres.2008.02.011  0.59
2008 de Toledo-Silva G, Siebert MN, Medeiros ID, Sincero TC, Moraes MO, Goldstone JV, Bainy AC. Cloning a new cytochrome P450 isoform (CYP356A1) from oyster Crassostrea gigas. Marine Environmental Research. 66: 15-8. PMID 18395786 DOI: 10.1016/j.marenvres.2008.02.010  0.344
2007 Goldstone JV, Goldstone HM, Morrison AM, Tarrant A, Kern SE, Woodin BR, Stegeman JJ. Cytochrome P450 1 genes in early deuterostomes (tunicates and sea urchins) and vertebrates (chicken and frog): origin and diversification of the CYP1 gene family. Molecular Biology and Evolution. 24: 2619-31. PMID 17916789 DOI: 10.1093/Molbev/Msm200  0.588
2007 Jönsson ME, Orrego R, Woodin BR, Goldstone JV, Stegeman JJ. Basal and 3,3',4,4',5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in zebrafish. Toxicology and Applied Pharmacology. 221: 29-41. PMID 17445853 DOI: 10.1016/J.Taap.2007.02.017  0.586
2007 Prasad JC, Goldstone JV, Camacho CJ, Vajda S, Stegeman JJ. Ensemble modeling of substrate binding to cytochromes P450: analysis of catalytic differences between CYP1A orthologs. Biochemistry. 46: 2640-54. PMID 17300179 DOI: 10.1021/Bi062320M  0.519
2006 Goldstone JV, Hamdoun A, Cole BJ, Howard-Ashby M, Nebert DW, Scally M, Dean M, Epel D, Hahn ME, Stegeman JJ. The chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genome. Developmental Biology. 300: 366-84. PMID 17097629 DOI: 10.1016/J.Ydbio.2006.08.066  0.552
2006 Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, ... ... Goldstone JV, et al. The genome of the sea urchin Strongylocentrotus purpuratus. Science (New York, N.Y.). 314: 941-52. PMID 17095691 DOI: 10.1126/Science.1133609  0.455
2006 Verslycke T, Goldstone JV, Stegeman JJ. Isolation and phylogeny of novel cytochrome P450 genes from tunicates (Ciona spp.): a CYP3 line in early deuterostomes? Molecular Phylogenetics and Evolution. 40: 760-71. PMID 16777437 DOI: 10.1016/J.Ympev.2006.04.017  0.576
2006 Schlezinger JJ, Struntz WD, Goldstone JV, Stegeman JJ. Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners. Aquatic Toxicology (Amsterdam, Netherlands). 77: 422-32. PMID 16500718 DOI: 10.1016/J.Aquatox.2006.01.012  0.701
2005 Godard CA, Goldstone JV, Said MR, Dickerson RL, Woodin BR, Stegeman JJ. The new vertebrate CYP1C family: cloning of new subfamily members and phylogenetic analysis. Biochemical and Biophysical Research Communications. 331: 1016-24. PMID 15882979 DOI: 10.1016/J.Bbrc.2005.03.231  0.775
2004 Goldstone JV, Del Vecchio R, Blough NV, Voelker BM. A multicomponent model of chromophoric dissolved organic matter photobleaching. Photochemistry and Photobiology. 80: 52-60. PMID 15339217 DOI: 10.1562/Tm-03-17.1  0.651
2004 Pullin MJ, Bertilsson S, Goldstone JV, Voelker BM. Effects of sunlight and hydroxyl radical on dissolved organic matter: Bacterial growth efficiency and production of carboxylic acids and other substrates Limnology and Oceanography. 49: 2011-2022. DOI: 10.4319/Lo.2004.49.6.2011  0.666
2002 Goldstone JV, Pullin MJ, Bertilsson S, Voelker BM. Reactions of hydroxyl radical with humic substances: bleaching, mineralization, and production of bioavailable carbon substrates. Environmental Science & Technology. 36: 364-72. PMID 11871550 DOI: 10.1021/Es0109646  0.671
2000 Goldstone JV, Voelker BM. Chemistry of superoxide radical in seawater: CDOM associated sink of superoxide in coastal waters Environmental Science and Technology. 34: 1043-1048. DOI: 10.1021/es9905445  0.661
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