Timothy K. Lu - Publications

Affiliations: 
Electrical Engineering and Computer Science Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
synthetic biology
Website:
http://www.fas.harvard.edu/~biophys/Timothy_K_Lu.htm

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cândido ES, Cardoso MH, Chan LY, Torres MT, Oshiro K, Porto WF, Ribeiro SM, Haney EF, Hancock REW, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential. Acs Infectious Diseases. PMID 31016969 DOI: 10.1021/acsinfecdis.9b00073  0.36
2019 Fensterseifer ICM, Felício MR, Alves ESF, Cardoso MH, Torres MDT, Matos CO, Silva ON, Lu TK, Freire MV, Neves NC, Gonçalves S, Lião LM, Santos NC, Porto WF, de la Fuente-Nunez C, et al. Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria. Biochimica Et Biophysica Acta. Biomembranes. PMID 30926365 DOI: 10.1016/j.bbamem.2019.03.016  0.36
2019 Mao X, Li K, Liu M, Wang X, Zhao T, An B, Cui M, Li Y, Pu J, Li J, Wang L, Lu TK, Fan C, Zhong C. Directing curli polymerization with DNA origami nucleators. Nature Communications. 10: 1395. PMID 30918257 DOI: 10.1038/s41467-019-09369-6  0.44
2019 Ahmed A, Siman-Tov G, Keck F, Kortchak S, Bakovic A, Risner K, Lu TK, Bhalla N, de la Fuente-Nunez C, Narayanan A. Human cathelicidin peptide LL-37 as a therapeutic antiviral targeting Venezuelan equine encephalitis virus infections. Antiviral Research. PMID 30738837 DOI: 10.1016/j.antiviral.2019.02.002  0.36
2019 Torres MDT, Sothiselvam S, Lu TK, de la Fuente-Nunez C. Peptide Design Principles for Antimicrobial Applications. Journal of Molecular Biology. PMID 30611750 DOI: 10.1016/j.jmb.2018.12.015  0.36
2018 Torres MDT, Pedron CN, Higashikuni Y, Kramer RM, Cardoso MH, Oshiro KGN, Franco OL, Silva Junior PI, Silva FD, Oliveira Junior VX, Lu TK, de la Fuente-Nunez C. Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. Communications Biology. 1: 221. PMID 30534613 DOI: 10.1038/s42003-018-0224-2  0.36
2018 Huang J, Liu S, Zhang C, Wang X, Pu J, Ba F, Xue S, Ye H, Zhao T, Li K, Wang Y, Zhang J, Wang L, Fan C, Lu TK, et al. Programmable and printable Bacillus subtilis biofilms as engineered living materials. Nature Chemical Biology. PMID 30510190 DOI: 10.1038/s41589-018-0169-2  0.44
2018 Cardoso M, Cândido E, Chan L, Torres MT, Oshiro K, Rezende S, Porto WF, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A computationally designed peptide derived from Escherichia colias a potential drug template for antibacterial and antibiofilm therapies. Acs Infectious Diseases. PMID 30346140 DOI: 10.1021/acsinfecdis.8b00219  0.36
2018 Pane K, Cafaro V, Avitabile A, Torres MT, Vollaro A, De Gregorio E, Catania MR, Di Maro A, Bosso A, Gallo G, Zanfardino A, Varcamonti M, Pizzo E, Di Donato A, Lu TK, et al. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. Acs Synthetic Biology. PMID 30124040 DOI: 10.1021/acssynbio.8b00084  0.36
2018 Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires ÁS, Fensterseifer ICM, Miranda VJ, Haney EF, Humblot V, Torres MDT, Hancock REW, Liao LM, Ladram A, Lu TK, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications. 9: 1490. PMID 29662055 DOI: 10.1038/s41467-018-03746-3  0.36
2018 Cao J, de la Fuente-Nunez C, Ou RW, Torres MD, Pande SG, Sinskey AJ, Lu TK. Yeast-based synthetic biology platform for antimicrobial peptide production. Acs Synthetic Biology. PMID 29366323 DOI: 10.1021/acssynbio.7b00396  0.36
2018 Cao J, Perez-Pinera P, Lowenhaupt K, Wu MR, Purcell O, de la Fuente-Nunez C, Lu TK. Versatile and on-demand biologics co-production in yeast. Nature Communications. 9: 77. PMID 29311542 DOI: 10.1038/s41467-017-02587-w  0.36
2017 de la Fuente-Nunez C, Meneguetti BT, Franco OL, Lu TK. Neuromicrobiology: How Microbes Influence the Brain. Acs Chemical Neuroscience. PMID 29220570 DOI: 10.1021/acschemneuro.7b00373  0.36
2017 Liu X, Yuk H, Lin S, Parada GA, Tang TC, Tham E, de la Fuente-Nunez C, Lu TK, Zhao X. 3D Printing of Living Responsive Materials and Devices. Advanced Materials (Deerfield Beach, Fla.). PMID 29205532 DOI: 10.1002/adma.201704821  0.36
2017 de la Fuente-Nunez C, Torres MD, Mojica FJ, Lu TK. Next-generation precision antimicrobials: towards personalized treatment of infectious diseases. Current Opinion in Microbiology. 37: 95-102. PMID 28623720 DOI: 10.1016/j.mib.2017.05.014  0.36
2017 An B, Wang X, Cui M, Gui X, Mao X, Liu Y, Li K, Chu C, Pu J, Ren S, Wang Y, Zhong G, Lu TK, Liu C, Zhong C. Diverse Supramolecular Nanofiber Networks Assembled by Functional Low-Complexity Domains. Acs Nano. PMID 28609612 DOI: 10.1021/acsnano.7b02298  0.44
2016 Perez-Pinera P, Han N, Cleto S, Cao J, Purcell O, Shah KA, Lee K, Ram R, Lu TK. Synthetic biology and microbioreactor platforms for programmable production of biologics at the point-of-care. Nature Communications. 7: 12211. PMID 27470089 DOI: 10.1038/ncomms12211  1
2016 Pires DP, Cleto S, Sillankorva S, Azeredo J, Lu TK. Genetically Engineered Phages: a Review of Advances over the Last Decade. Microbiology and Molecular Biology Reviews : Mmbr. 80: 523-43. PMID 27250768 DOI: 10.1128/MMBR.00069-15  1
2016 Mimee M, Citorik RJ, Lu TK. Microbiome therapeutics - Advances and challenges. Advanced Drug Delivery Reviews. PMID 27158095 DOI: 10.1016/j.addr.2016.04.032  1
2016 Zakeri B, Carr PA, Lu TK. Multiplexed Sequence Encoding: A Framework for DNA Communication. Plos One. 11: e0152774. PMID 27050646 DOI: 10.1371/journal.pone.0152774  1
2016 Ma KC, Perli SD, Lu TK. Foundations and Emerging Paradigms for Computing in Living Cells. Journal of Molecular Biology. PMID 26908220 DOI: 10.1016/j.jmb.2016.02.018  1
2016 Wong AS, Choi GC, Cui CH, Pregernig G, Milani P, Adam M, Perli SD, Kazer SW, Gaillard A, Hermann M, Shalek AK, Fraenkel E, Lu TK. Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. Proceedings of the National Academy of Sciences of the United States of America. PMID 26864203 DOI: 10.1073/pnas.1517883113  1
2016 Lu TK, Chandrasegaran S, Hodak H. The era of synthetic biology and genome engineering: Where no man has gone before. Journal of Molecular Biology. PMID 26827726 DOI: 10.1016/j.jmb.2016.01.025  1
2015 Wong AS, Choi GC, Cheng AA, Purcell O, Lu TK. Massively parallel high-order combinatorial genetics in human cells. Nature Biotechnology. 33: 952-61. PMID 26280411 DOI: 10.1038/nbt.3326  1
2015 Zakeri B, Lu TK. DNA nanotechnology: new adventures for an old warhorse. Current Opinion in Chemical Biology. 28: 9-14. PMID 26056949 DOI: 10.1016/j.cbpa.2015.05.020  1
2015 Chen AY, Zhong C, Lu TK. Engineering living functional materials. Acs Synthetic Biology. 4: 8-11. PMID 25592034 DOI: 10.1021/sb500113b  1
2015 Perez-Pinera P, Jones MF, Lal A, Lu TK. Putting Non-coding RNA on Display with CRISPR Molecular Cell. 59: 146-148. DOI: 10.1016/j.molcel.2015.07.002  1
2015 Ando H, Lemire S, Pires DP, Lu TK. Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing Cell Systems. 1: 187-196. DOI: 10.1016/j.cels.2015.08.013  1
2015 Mimee M, Tucker AC, Voigt CA, Lu TK. Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota Cell Systems. DOI: 10.1016/j.cels.2015.06.001  1
2014 Farzadfard F, Lu TK. Synthetic biology. Genomically encoded analog memory with precise in vivo DNA writing in living cell populations. Science (New York, N.Y.). 346: 1256272. PMID 25395541 DOI: 10.1126/science.1256272  1
2014 Yang L, Nielsen AA, Fernandez-Rodriguez J, McClune CJ, Laub MT, Lu TK, Voigt CA. Permanent genetic memory with >1-byte capacity. Nature Methods. 11: 1261-6. PMID 25344638 DOI: 10.1038/nmeth.3147  1
2014 Citorik RJ, Mimee M, Lu TK. Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases. Nature Biotechnology. 32: 1141-5. PMID 25240928 DOI: 10.1038/nbt.3011  1
2014 Zhong C, Gurry T, Cheng AA, Downey J, Deng Z, Stultz CM, Lu TK. Strong underwater adhesives made by self-assembling multi-protein nanofibres. Nature Nanotechnology. 9: 858-66. PMID 25240674 DOI: 10.1038/nnano.2014.199  1
2014 Cheng AA, Ding H, Lu TK. Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics. Proceedings of the National Academy of Sciences of the United States of America. 111: 12462-7. PMID 25114216 DOI: 10.1073/pnas.1400093111  1
2014 Citorik RJ, Mimee M, Lu TK. Bacteriophage-based synthetic biology for the study of infectious diseases. Current Opinion in Microbiology. 19: 59-69. PMID 24997401 DOI: 10.1016/j.mib.2014.05.022  1
2014 Purcell O, Peccoud J, Lu TK. Rule-based design of synthetic transcription factors in eukaryotes. Acs Synthetic Biology. 3: 737-44. PMID 24933274 DOI: 10.1021/sb400134k  1
2014 Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK. Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Molecular Cell. 54: 698-710. PMID 24837679 DOI: 10.1016/j.molcel.2014.04.022  1
2014 Siuti P, Yazbek J, Lu TK. Engineering genetic circuits that compute and remember. Nature Protocols. 9: 1292-300. PMID 24810038 DOI: 10.1038/nprot.2014.089  1
2014 Purcell O, Lu TK. Synthetic analog and digital circuits for cellular computation and memory. Current Opinion in Biotechnology. 29: 146-55. PMID 24794536 DOI: 10.1016/j.copbio.2014.04.009  1
2014 Roquet N, Lu TK. Digital and analog gene circuits for biotechnology. Biotechnology Journal. 9: 597-608. PMID 24677719 DOI: 10.1002/biot.201300258  1
2014 Chen AY, Deng Z, Billings AN, Seker UO, Lu MY, Citorik RJ, Zakeri B, Lu TK. Synthesis and patterning of tunable multiscale materials with engineered cells. Nature Materials. 13: 515-23. PMID 24658114 DOI: 10.1038/nmat3912  1
2014 Billings N, Lu TK, Ribbeck K. A bacteriophage infectivity assay to probe particle transport through mucus and biofilm matrices Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec. 2014. DOI: 10.1109/NEBEC.2014.6972733  1
2014 Ando H, Citorik R, Cleto S, Lemire S, Mimee M, Lu T. Synthetic Biology and Therapies for Infectious Diseases Novel Antimicrobial Agents and Strategies. 109-180. DOI: 10.1002/9783527676132.ch7  1
2014 Han N, Purcell O, Farzadfard F, Lee KS, Lu TK, Ram RJ. Microfluidics for control in synthetic biology 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 312-314.  1
2013 Farzadfard F, Perli SD, Lu TK. Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas. Acs Synthetic Biology. 2: 604-13. PMID 23977949 DOI: 10.1021/sb400081r  1
2013 Purcell O, Jain B, Karr JR, Covert MW, Lu TK. Towards a whole-cell modeling approach for synthetic biology. Chaos (Woodbury, N.Y.). 23: 025112. PMID 23822510 DOI: 10.1063/1.4811182  1
2013 Daniel R, Rubens JR, Sarpeshkar R, Lu TK. Synthetic analog computation in living cells. Nature. 497: 619-23. PMID 23676681 DOI: 10.1038/nature12148  1
2013 Zakeri B, Lu TK. Synthetic biology of antimicrobial discovery. Acs Synthetic Biology. 2: 358-72. PMID 23654251 DOI: 10.1021/sb300101g  1
2013 Lu TK, Bowers J, Koeris MS. Advancing bacteriophage-based microbial diagnostics with synthetic biology. Trends in Biotechnology. 31: 325-7. PMID 23608522 DOI: 10.1016/j.tibtech.2013.03.009  1
2013 Siuti P, Yazbek J, Lu TK. Synthetic circuits integrating logic and memory in living cells. Nature Biotechnology. 31: 448-52. PMID 23396014 DOI: 10.1038/nbt.2510  1
2013 Khalil AS, Bashor CJ, Lu TK. Engineering life Scientist. 27.  1
2012 Khalil AS, Lu TK, Bashor CJ, Ramirez CL, Pyenson NC, Joung JK, Collins JJ. A synthetic biology framework for programming eukaryotic transcription functions. Cell. 150: 647-58. PMID 22863014 DOI: 10.1016/j.cell.2012.05.045  1
2012 Cheng AA, Lu TK. Synthetic biology: an emerging engineering discipline. Annual Review of Biomedical Engineering. 14: 155-78. PMID 22577777 DOI: 10.1146/annurev-bioeng-071811-150118  1
2012 Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC. Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics. Acs Nano. 6: 4279-87. PMID 22471841 DOI: 10.1021/nn3008383  1
2011 Lu TK, Koeris MS. The next generation of bacteriophage therapy. Current Opinion in Microbiology. 14: 524-31. PMID 21868281 DOI: 10.1016/j.mib.2011.07.028  1
2011 Kaseniit KE, Perli SD, Lu TK. Designing extensible protein-DNA interactions for synthetic biology 2011 Ieee Biomedical Circuits and Systems Conference, Biocas 2011. 349-352. DOI: 10.1109/BioCAS.2011.6107799  1
2010 Lu TK. Engineering scalable biological systems. Bioengineered Bugs. 1: 378-84. PMID 21468204 DOI: 10.4161/bbug.1.6.13086  1
2009 Lu TK, Khalil AS, Collins JJ. Next-generation synthetic gene networks. Nature Biotechnology. 27: 1139-50. PMID 20010597 DOI: 10.1038/nbt.1591  1
2009 Friedland AE, Lu TK, Wang X, Shi D, Church G, Collins JJ. Synthetic gene networks that count. Science (New York, N.Y.). 324: 1199-202. PMID 19478183 DOI: 10.1126/science.1172005  1
2009 Lu TK, Collins JJ. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 4629-34. PMID 19255432 DOI: 10.1073/pnas.0800442106  1
2009 Lu TK, Collins JJ. Engineering synthetic bacteriophage to combat antibiotic-resistant bacteria Bioengineering, Proceedings of the Northeast Conference. DOI: 10.1109/NEBC.2009.4967831  0.92
2007 Lu TK, Collins JJ. Dispersing biofilms with engineered enzymatic bacteriophage. Proceedings of the National Academy of Sciences of the United States of America. 104: 11197-202. PMID 17592147 DOI: 10.1073/pnas.0704624104  1
2006 Lu TK, Zhak S, Dallos P, Sarpeshkar R. Fast cochlear amplification with slow outer hair cells. Hearing Research. 214: 45-67. PMID 16603325 DOI: 10.1016/j.heares.2006.01.018  1
2005 Sarpeshkar R, Salthouse C, Sit JJ, Baker MW, Zhak SM, Lu TK, Turicchia L, Balster S. An ultra-low-power programmable analog bionic ear processor. Ieee Transactions On Bio-Medical Engineering. 52: 711-27. PMID 15825873 DOI: 10.1109/TBME.2005.844043  1
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