| Year |
Citation |
Score |
| 2023 |
Houszka N, Mikula H, Svatunek D. Substituent Effects in Bioorthogonal Diels-Alder Reactions of 1,2,4,5-Tetrazines. Chemistry (Weinheim An Der Bergstrasse, Germany). e202300345. PMID 36853623 DOI: 10.1002/chem.202300345 |
0.787 |
|
| 2022 |
Kuba W, Sohr B, Keppel P, Svatunek D, Humhal V, Stöger B, Goldeck M, Carlson JCT, Mikula H. Oxidative Desymmetrization Enables the Concise Synthesis of a trans-Cyclooctene Linker for Bioorthogonal Bond-Cleavage. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36250260 DOI: 10.1002/chem.202203069 |
0.786 |
|
| 2022 |
Ko J, Wilkovitsch M, Oh J, Kohler RH, Bolli E, Pittet MJ, Vinegoni C, Sykes DB, Mikula H, Weissleder R, Carlson JCT. Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nature Biotechnology. PMID 35654978 DOI: 10.1038/s41587-022-01339-6 |
0.326 |
|
| 2022 |
Svatunek D, Wilkovitsch M, Hartmann L, Houk KN, Mikula H. Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the Reactivity/Stability Trade-Off. Journal of the American Chemical Society. 144: 8171-8177. PMID 35500228 DOI: 10.1021/jacs.2c01056 |
0.78 |
|
| 2022 |
Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, ... ... Mikula H, et al. Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Science Advances. 8: eabl6339. PMID 35486732 DOI: 10.1126/sciadv.abl6339 |
0.304 |
|
| 2022 |
Battisti UM, García-Vázquez R, Svatunek D, Herrmann B, Löffler A, Mikula H, Herth MM. Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines. Bioconjugate Chemistry. PMID 35290735 DOI: 10.1021/acs.bioconjchem.2c00042 |
0.791 |
|
| 2022 |
Svatunek D, Houszka N, Hamlin TA, Bickelhaupt FM, Mikula H. Corrigendum: Chemoselectivity of Tertiary Azides in Strain-Promoted Alkyne-Azide Cycloadditions. Chemistry (Weinheim An Der Bergstrasse, Germany). 28: e202200414. PMID 35285565 DOI: 10.1002/chem.202200414 |
0.736 |
|
| 2021 |
García-Vázquez R, Battisti UM, Jørgensen JT, Shalgunov V, Hvass L, Stares DL, Petersen IN, Crestey F, Löffler A, Svatunek D, Kristensen JL, Mikula H, Kjaer A, Herth MM. Direct Cu-mediated aromatic F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging. Chemical Science. 12: 11668-11675. PMID 34659701 DOI: 10.1039/d1sc02789a |
0.776 |
|
| 2021 |
Stéen EJL, Jørgensen JT, Denk C, Battisti UM, Nørregaard K, Edem PE, Bratteby K, Shalgunov V, Wilkovitsch M, Svatunek D, Poulie CBM, Hvass L, Simón M, Wanek T, Rossin R, ... ... Mikula H, et al. Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted Chemistry. Acs Pharmacology & Translational Science. 4: 824-833. PMID 33860205 DOI: 10.1021/acsptsci.1c00007 |
0.79 |
|
| 2020 |
Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT, Mikula H. A Cleavable C-Symmetric -Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes. Journal of the American Chemical Society. PMID 33119297 DOI: 10.1021/jacs.0c07922 |
0.406 |
|
| 2020 |
Svatunek D, Eilenberger G, Denk C, Lumpi D, Hametner C, Allmaier G, Mikula H. Live Monitoring of Strain-Promoted Azide Alkyne Cycloadditions in Complex Reaction Environments by Inline ATR-IR Spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31944448 DOI: 10.1002/Chem.201905478 |
0.785 |
|
| 2020 |
Johann K, Svatunek D, Seidl C, Rizzelli S, Bauer TA, Braun L, Koynov K, Mikula H, Barz M. Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides for fast bioorthogonal tetrazine ligation Polymer Chemistry. 11: 4396-4407. DOI: 10.1039/D0Py00375A |
0.758 |
|
| 2019 |
Stéen EJL, Jørgensen JT, Johann K, Norregaard K, Sohr B, Svatunek D, Birke A, Shalgunov V, Edem PE, Rossin R, Seidl C, Schmid F, Robillard MS, Kristensen JL, Mikula H, et al. Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging. Acs Nano. PMID 31820928 DOI: 10.1021/Acsnano.9B06905 |
0.774 |
|
| 2019 |
Levandowski BJ, Svatunek D, Sohr B, Mikula H, Houk KN. Correction to "Secondary Orbital Interactions Enhance the Reactivity of Alkynes in Diels-Alder Cycloadditions". Journal of the American Chemical Society. 141: 18641. PMID 31692340 DOI: 10.1021/Jacs.9B11320 |
0.759 |
|
| 2019 |
Denk C, Wilkovitsch M, Aneheim E, Herth MM, Jensen H, Lindegren S, Mikula H. Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio-Crosslinking. Chempluschem. 84: 775-778. PMID 31681526 DOI: 10.1002/Cplu.201900114 |
0.369 |
|
| 2019 |
Weber J, Svatunek D, Krauter S, Tegl G, Hametner C, Kosma P, Mikula H. 2-O-Benzyloxycarbonyl protected glycosyl donors: a revival of carbonate-mediated anchimeric assistance for diastereoselective glycosylation. Chemical Communications (Cambridge, England). PMID 31576821 DOI: 10.1039/C9Cc07194F |
0.769 |
|
| 2019 |
Kramer S, Svatunek D, Alberg I, Gräfen B, Schmitt S, Braun L, van Onzen AHAM, Rossin R, Koynov K, Mikula H, Zentel R. HPMA-Based Nanoparticles for Fast, Bioorthogonal iEDDA Ligation. Biomacromolecules. PMID 31535846 DOI: 10.1021/Acs.Biomac.9B00868 |
0.77 |
|
| 2019 |
Stéen EJL, Shalgunov V, Denk C, Mikula H, Kjær A, Kristensen JL, Herth MM. Convenient Entry to F-Labeled Amines through the Staudinger Reduction. European Journal of Organic Chemistry. 2019: 1722-1725. PMID 31007573 DOI: 10.1002/Ejoc.201801457 |
0.369 |
|
| 2019 |
Rosecker V, Denk C, Maurer M, Wilkovitsch M, Mairinger S, Wanek T, Mikula H. Cross-Isotopic Bioorthogonal Tools as Molecular Twins for Radiotheranostic Applications. Chembiochem : a European Journal of Chemical Biology. PMID 30742739 DOI: 10.1002/Cbic.201900042 |
0.369 |
|
| 2019 |
Levandowski BJ, Svatunek D, Sohr B, Mikula H, Houk KN. Secondary Orbital Interactions Enhance the Reactivity of Alkynes in Diels-Alder Cycloadditions. Journal of the American Chemical Society. 141: 2224-2227. PMID 30693769 DOI: 10.1021/Jacs.8B13088 |
0.775 |
|
| 2019 |
Denk C, Wilkovitsch M, Aneheim E, Herth MM, Jensen H, Lindegren S, Mikula H. Front Cover: Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio‐Crosslinking (ChemPlusChem 7/2019) Chempluschem. 84: 772-772. DOI: 10.1002/Cplu.201900238 |
0.303 |
|
| 2018 |
Miller MA, Mikula H, Luthria G, Li R, Kronister S, Prytyskach M, Kohler RH, Mitchison T, Weissleder R. Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. Acs Nano. PMID 30550257 DOI: 10.1021/Acsnano.8B07954 |
0.428 |
|
| 2018 |
Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ. Site occupancy calibration of taxane pharmacology in live cells and tissues. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429313 DOI: 10.1073/Pnas.1800047115 |
0.377 |
|
| 2018 |
Svatunek D, Houszka N, Hamlin T, Bickelhaupt M, Mikula H. Chemoselectivity of Tertiary Azides in Strain-Promoted Alkyne-Azide Cycloadditions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30347481 DOI: 10.1002/Chem.201805215 |
0.79 |
|
| 2018 |
Weber J, Schwarz M, Schiefer A, Hametner C, Häubl G, Fröhlich J, Mikula H. Chemical Glucosylation of Labile Natural Products Using a (2-Nitrophenyl)acetyl-Protected Glucosyl Acetimidate Donor. European Journal of Organic Chemistry. 2018: 2701-2706. PMID 29937688 DOI: 10.1002/Ejoc.201800260 |
0.544 |
|
| 2018 |
Puntscher H, Kütt ML, Skrinjar P, Mikula H, Podlech J, Fröhlich J, Marko D, Warth B. Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins. Analytical and Bioanalytical Chemistry. PMID 29766221 DOI: 10.1007/S00216-018-1105-8 |
0.498 |
|
| 2018 |
Svatunek D, Denk C, Mikula H. A computational model to predict the Diels-Alder reactivity of aryl/alkyl-substituted tetrazines. Monatshefte Fur Chemie. 149: 833-837. PMID 29681659 DOI: 10.1007/S00706-017-2110-X |
0.78 |
|
| 2018 |
Weber J, Vaclavikova M, Wiesenberger G, Haider M, Hametner C, Fröhlich J, Berthiller F, Adam G, Mikula H, Fruhmann P. Chemical synthesis of culmorin metabolites and their biologic role in culmorin and acetyl-culmorin treated wheat cells. Organic & Biomolecular Chemistry. PMID 29465119 DOI: 10.1039/C7Ob02460F |
0.548 |
|
| 2018 |
Carlson J, Mikula H, Weissleder R. Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage. Journal of the American Chemical Society. PMID 29384666 DOI: 10.1021/Jacs.7B11217 |
0.469 |
|
| 2018 |
Dellafiora L, Warth B, Schmidt V, Del Favero G, Mikula H, Fröhlich J, Marko D. An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites. Food Chemistry. 248: 253-261. PMID 29329852 DOI: 10.1016/J.Foodchem.2017.12.013 |
0.513 |
|
| 2018 |
Weber J, Krauter S, Schwarz T, Hametner C, Mikula H. (2-Benzyloxyphenyl)acetyl (BnPAc): A Participating Relay Protecting Group for Diastereoselective Glycosylation and the Synthesis of 1,2-trans Glycosyl Esters Synlett. 29: 2265-2268. DOI: 10.1055/S-0037-1610255 |
0.303 |
|
| 2018 |
Mikula H, Kronister S, Svatunek D, Denk C. Acylation-Mediated ‘Kinetic Turn-On’ of 3-Amino-1,2,4,5-tetrazines Synlett. 29: 1297-1302. DOI: 10.1055/S-0036-1591764 |
0.792 |
|
| 2017 |
Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R. Nano-palladium is a cellular catalyst for in vivo chemistry. Nature Communications. 8: 15906. PMID 28699627 DOI: 10.1038/Ncomms15906 |
0.408 |
|
| 2017 |
Denk C, Wilkovitsch M, Skrinjar P, Svatunek D, Mairinger S, Kuntner C, Filip T, Fröhlich J, Wanek T, Mikula H. [(18)F]Fluoroalkyl azides for rapid radiolabeling and (Re)investigation of their potential towards in vivo click chemistry. Organic & Biomolecular Chemistry. PMID 28678258 DOI: 10.1039/C7Ob00880E |
0.787 |
|
| 2017 |
Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R. Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging. Theranostics. 7: 1257-1265. PMID 28435463 DOI: 10.7150/Thno.18238 |
0.423 |
|
| 2017 |
Bintinger J, Yang S, Fruhmann P, Holzer B, Stöger B, Svirkova A, Marchetti-Deschmann M, Horkel E, Hametner C, Fröhlich J, Kymissis I, Mikula H. Synthesis, characterization and printing application of alkylated indolo[3,2-b]carbazoles Synthetic Metals. 228: 9-17. DOI: 10.1016/J.Synthmet.2017.04.003 |
0.528 |
|
| 2017 |
Weber J, Fruhmann P, Hametner C, Schiessl A, Häubl G, Fröhlich J, Mikula H. Front Cover: Synthesis of Isotope‐Labeled Deoxynivalenol‐15‐O‐Glycosides (Eur. J. Org. Chem. 47/2017) European Journal of Organic Chemistry. 2017: 7005-7005. DOI: 10.1002/Ejoc.201701632 |
0.52 |
|
| 2017 |
Weber J, Fruhmann P, Hametner C, Schiessl A, Häubl G, Fröhlich J, Mikula H. Synthesis of Isotope‐Labeled Deoxynivalenol‐15‐O‐Glycosides European Journal of Organic Chemistry. 2017: 7012-7018. DOI: 10.1002/Ejoc.201700934 |
0.529 |
|
| 2016 |
Meimetis LG, Giedt RJ, Mikula H, Carlson JC, Kohler RH, Pirovich DB, Weissleder R. Fluorescent vinblastine probes for live cell imaging. Chemical Communications (Cambridge, England). PMID 27439765 DOI: 10.1039/C6Cc04129A |
0.432 |
|
| 2016 |
Tiessen C, Ellmer D, Mikula H, Pahlke G, Warth B, Gehrke H, Zimmermann K, Heiss E, Fröhlich J, Marko D. Impact of phase I metabolism on uptake, oxidative stress and genotoxicity of the emerging mycotoxin alternariol and its monomethyl ether in esophageal cells. Archives of Toxicology. PMID 27422292 DOI: 10.1007/S00204-016-1801-0 |
0.516 |
|
| 2016 |
Denk C, Svatunek D, Mairinger S, Stanek J, Filip T, Matscheko D, Kuntner C, Wanek T, Mikula H. Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry. Bioconjugate Chemistry. 27: 1707-12. PMID 27308894 DOI: 10.1021/Acs.Bioconjchem.6B00234 |
0.782 |
|
| 2016 |
Svatunek D, Denk C, Rosecker V, Sohr B, Hametner C, Allmaier G, Fröhlich J, Mikula H. Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization. Monatshefte Fur Chemie. 147: 579-585. PMID 27069284 DOI: 10.1007/S00706-016-1668-Z |
0.78 |
|
| 2015 |
Kim E, Yang KS, Kohler RH, Dubach JM, Mikula H, Weissleder R. Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression. Bioconjugate Chemistry. PMID 26017814 DOI: 10.1021/Acs.Bioconjchem.5B00152 |
0.446 |
|
| 2014 |
Fruhmann P, Skrinjar P, Weber J, Mikula H, Warth B, Sulyok M, Krska R, Adam G, Rosenberg E, Hametner C, Fröhlich J. Sulfation of deoxynivalenol, its acetylated derivatives, and T2-toxin. Tetrahedron. 70: 5260-5266. PMID 25170180 DOI: 10.1016/J.Tet.2014.05.064 |
0.528 |
|
| 2014 |
Mikula H, Weber J, Svatunek D, Skrinjar P, Adam G, Krska R, Hametner C, Fröhlich J. Synthesis of zearalenone-16-β,D-glucoside and zearalenone-16-sulfate: A tale of protecting resorcylic acid lactones for regiocontrolled conjugation. Beilstein Journal of Organic Chemistry. 10: 1129-34. PMID 24991263 DOI: 10.3762/Bjoc.10.112 |
0.784 |
|
| 2014 |
Denk C, Svatunek D, Filip T, Wanek T, Lumpi D, Fröhlich J, Kuntner C, Mikula H. Development of a (18) F-labeled tetrazine with favorable pharmacokinetics for bioorthogonal PET imaging. Angewandte Chemie (International Ed. in English). 53: 9655-9. PMID 24989029 DOI: 10.1002/Anie.201404277 |
0.784 |
|
| 2014 |
Fruhmann P, Weigl-Pollack T, Mikula H, Wiesenberger G, Adam G, Varga E, Berthiller F, Krska R, Hametner C, Fröhlich J. Methylthiodeoxynivalenol (MTD): insight into the chemistry, structure and toxicity of thia-Michael adducts of trichothecenes. Organic & Biomolecular Chemistry. 12: 5144-50. PMID 24903010 DOI: 10.1039/C4Ob00458B |
0.57 |
|
| 2014 |
Mikula H, Svatunek D, Skrinjar P, Horkel E, Hametner C, Fröhlich J. DFT study of the Lewis acid mediated synthesis of 3-acyltetramic acids. Journal of Molecular Modeling. 20: 2181. PMID 24794137 DOI: 10.1007/S00894-014-2181-0 |
0.779 |
|
| 2014 |
Fruhmann P, Hametner C, Mikula H, Adam G, Krska R, Fröhlich J. Stereoselective Luche reduction of deoxynivalenol and three of its acetylated derivatives at C8. Toxins. 6: 325-36. PMID 24434906 DOI: 10.3390/Toxins6010325 |
0.57 |
|
| 2014 |
Fruhmann P, Mikula H, Wiesenberger G, Varga E, Lumpi D, Stöger B, Häubl G, Lemmens M, Berthiller F, Krska R, Adam G, Hametner C, Fröhlich J. Isolation and structure elucidation of pentahydroxyscirpene, a trichothecene Fusarium mycotoxin. Journal of Natural Products. 77: 188-92. PMID 24367932 DOI: 10.1021/Np4008365 |
0.496 |
|
| 2014 |
Denk C, Svatunek D, Filip T, Wanek T, Lumpi D, Fröhlich J, Kuntner C, Mikula H. Inside Back Cover: Development of a18F-Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging (Angew. Chem. Int. Ed. 36/2014) Angewandte Chemie International Edition. 53: 9675-9675. DOI: 10.1002/Anie.201406154 |
0.764 |
|
| 2014 |
Denk C, Svatunek D, Filip T, Wanek T, Lumpi D, Fröhlich J, Kuntner C, Mikula H. Innenrücktitelbild: Entwicklung eines18F-markierten Tetrazins mit vorteilhaften pharmakokinetischen Eigenschaften für die bioorthogonale Positronenemissionstomographie (Angew. Chem. 36/2014) Angewandte Chemie. 126: 9829-9829. DOI: 10.1002/Ange.201406154 |
0.742 |
|
| 2014 |
Denk C, Svatunek D, Filip T, Wanek T, Lumpi D, Fröhlich J, Kuntner C, Mikula H. Entwicklung eines18F-markierten Tetrazins mit vorteilhaften pharmakokinetischen Eigenschaften für die bioorthogonale Positronenemissionstomographie Angewandte Chemie. 126: 9810-9814. DOI: 10.1002/Ange.201404277 |
0.736 |
|
| 2013 |
Mikula H, Horkel E, Hans P, Hametner C, Fröhlich J. Structure and tautomerism of tenuazonic acid--a synergetic computational and spectroscopic approach. Journal of Hazardous Materials. 250: 308-17. PMID 23474405 DOI: 10.1016/J.Jhazmat.2013.02.006 |
0.505 |
|
| 2013 |
Mikula H, Matscheko D, Schwarz M, Hametner C, Fröhlich J. Improved and large-scale synthesis of different protected D-glucuronals. Carbohydrate Research. 370: 19-23. PMID 23419943 DOI: 10.1016/J.Carres.2013.01.007 |
0.527 |
|
| 2013 |
Mikula H, Hametner C, Fröhlich J. Zearalenone mimics: Synthesis of (E)-6-(1-Alkenyl)-substituted β-resorcylic acid esters Synthetic Communications. 43: 1939-1946. DOI: 10.1080/00397911.2012.681827 |
0.551 |
|
| 2013 |
Weber J, Mikula H, Fruhmann P, Hametner C, Varga E, Berthiller F, Krska R, Fröhlich J. Gentiobiosylation of β-resorcylic acid esters and lactones: First synthesis and characterization of zearalenone-14-β,d-gentiobioside Synlett. 24: 1830-1834. DOI: 10.1055/S-0033-1339338 |
0.507 |
|
| 2013 |
Mikula H, Svatunek D, Lumpi D, Glöcklhofer F, Hametner C, Fröhlich J. Practical and efficient large-scale preparation of dimethyldioxirane Organic Process Research and Development. 17: 313-316. DOI: 10.1021/Op300338Q |
0.769 |
|
| 2013 |
Mikula H, Skrinjar P, Sohr B, Ellmer D, Hametner C, Fröhlich J. Total synthesis of masked Alternaria mycotoxins - Sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME) Tetrahedron. 69: 10322-10330. DOI: 10.1016/J.Tet.2013.10.008 |
0.583 |
|
| 2012 |
Warth B, Sulyok M, Fruhmann P, Mikula H, Berthiller F, Schuhmacher R, Hametner C, Abia WA, Adam G, Fröhlich J, Krska R. Development and validation of a rapid multi-biomarker liquid chromatography/tandem mass spectrometry method to assess human exposure to mycotoxins. Rapid Communications in Mass Spectrometry : Rcm. 26: 1533-40. PMID 22638970 DOI: 10.1002/Rcm.6255 |
0.479 |
|
| 2012 |
Mikula H, Hametner C, Berthiller F, Warth B, Krska R, Adam G, Fröhlich J. Fast and reproducible chemical synthesis of zearalenone-14-β,D-glucuronide World Mycotoxin Journal. 5: 289-296. DOI: 10.3920/Wmj2012.1404 |
0.494 |
|
| Show low-probability matches. |