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Haoqing Wang - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
structural biology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kumar KK, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Step-wise activation of a Family C GPCR. Biorxiv : the Preprint Server For Biology. PMID 37693614 DOI: 10.1101/2023.08.29.555158  0.49
2023 Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B. Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672. PMID 37160876 DOI: 10.1038/s41467-023-37864-4  0.507
2023 Krishna Kumar K, O'Brien ES, Habrian CH, Latorraca NR, Wang H, Tuneew I, Montabana E, Marqusee S, Hilger D, Isacoff EY, Mathiesen JM, Kobilka BK. Negative allosteric modulation of the glucagon receptor by RAMP2. Cell. 186: 1465-1477.e18. PMID 37001505 DOI: 10.1016/j.cell.2023.02.028  0.457
2023 Xu J, Wang Q, Hübner H, Hu Y, Niu X, Wang H, Maeda S, Inoue A, Tao Y, Gmeiner P, Du Y, Jin C, Kobilka BK. Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature Communications. 14: 376. PMID 36690613 DOI: 10.1038/s41467-022-35726-z  0.497
2022 Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, et al. Structure-based design of bitopic ligands for the µ-opioid receptor. Nature. PMID 36450356 DOI: 10.1038/s41586-022-05588-y  0.466
2022 Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, et al. Insights into distinct signaling profiles of the µOR activated by diverse agonists. Nature Chemical Biology. PMID 36411392 DOI: 10.1038/s41589-022-01208-y  0.469
2022 Gmeiner P, Wang H, Hetzer F, Huang W, Qu Q, Meyerowitz J, Kaindl J, Hübner H, Skiniotis G, Kobilka BK. Structure-based Evolution of G protein-biased μ-opioid Receptor Agonists. Angewandte Chemie (International Ed. in English). PMID 35385593 DOI: 10.1002/anie.202200269  0.481
2022 Ghani L, Kim S, Wang H, Lee HS, Mortensen JS, Katsube S, Du Y, Sadaf A, Byrne B, Guan L, Loland CJ, Kobilka BK, Im W, Chae PS, Ahmed W. Foldable detergents for membrane protein study: Importance of detergent core flexibility in protein stabilization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35238091 DOI: 10.1002/chem.202200116  0.488
2022 Ehsan M, Wang H, Katsube S, Munk CF, Du Y, Youn T, Yoon S, Byrne B, Loland CJ, Guan L, Kobilka BK, Chae PS. Glyco-steroidal amphiphiles (GSAs) for membrane protein structural study. Chembiochem : a European Journal of Chemical Biology. PMID 35129249 DOI: 10.1002/cbic.202200027  0.494
2021 Escolano A, Gristick HB, Gautam R, DeLaitsch AT, Abernathy ME, Yang Z, Wang H, Hoffmann MAG, Nishimura Y, Wang Z, Koranda N, Kakutani LM, Gao H, Gnanapragasam PNP, Raina H, et al. Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env. Science Translational Medicine. 13: eabk1533. PMID 34818054 DOI: 10.1126/scitranslmed.abk1533  0.536
2021 Ehsan M, Wang H, Cecchetti C, Mortensen JS, Du Y, Hariharan P, Nygaard A, Lee HJ, Ghani L, Guan L, Loland CJ, Byrne B, Kobilka BK, Chae PS. Maltose-bis(hydroxymethyl)phenol (MBPs) and Maltose-tris(hydroxymethyl)phenol (MTPs) Amphiphiles for Membrane Protein Stability. Acs Chemical Biology. PMID 34445864 DOI: 10.1021/acschembio.1c00578  0.496
2021 Sadaf A, Kim S, Bae HE, Wang H, Nygaard A, Uegaki Y, Du Y, Munk CF, Katsube S, Bae J, Choi CW, Choi HJ, Byrne B, Gellman SH, Guan L, et al. Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability. Acta Biomaterialia. PMID 33933694 DOI: 10.1016/j.actbio.2021.04.043  0.481
2021 Cohen AA, Yang Z, Gnanapragasam PNP, Ou S, Dam KA, Wang H, Bjorkman PJ. Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers. Plos One. 16: e0247963. PMID 33661993 DOI: 10.1371/journal.pone.0247963  0.422
2020 Das M, Mahler F, Hariharan P, Wang H, Du Y, Mortensen JS, Patallo EP, Ghani L, Glück D, Lee HJ, Byrne B, Loland CJ, Guan L, Kobilka BK, Keller S, et al. Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study. Journal of the American Chemical Society. PMID 33315387 DOI: 10.1021/jacs.0c09629  0.498
2020 Ehsan M, Katsube S, Cecchetti C, Du Y, Mortensen JS, Wang H, Nygaard A, Ghani L, Loland CJ, Kobilka BK, Byrne B, Guan L, Chae PS. New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability. Acs Chemical Biology. PMID 32501004 DOI: 10.1021/Acschembio.0C00316  0.483
2020 Yang Z, Wang H, Liu AZ, Gristick HB, Bjorkman PJ. Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nature Structural & Molecular Biology. PMID 31965081 DOI: 10.1038/S41594-020-0381-0  0.59
2019 Yang Z, Wang H, Liu AZ, Gristick HB, Bjorkman PJ. Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nature Structural & Molecular Biology. PMID 31844248 DOI: 10.1038/s41594-019-0362-3  0.554
2019 Yang Z, Wang H, Liu AZ, Gristick HB, Bjorkman PJ. Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nature Structural & Molecular Biology. PMID 31792452 DOI: 10.1038/s41594-019-0344-5  0.615
2019 Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, et al. Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature. PMID 31142836 DOI: 10.1038/S41586-019-1250-Z  0.575
2019 Yang Z, Wang H, Liu AZ, Gristick HB, Bjorkman PJ. Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nature Structural & Molecular Biology. 26: 1167-1175. DOI: 10.2210/Pdb6U0L/Pdb  0.658
2018 Wang H, Barnes CO, Yang Z, Nussenzweig MC, Bjorkman PJ. Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host & Microbe. 24: 579-592.e4. PMID 30308160 DOI: 10.1016/j.chom.2018.09.003  0.61
2018 Wang H, Barnes CO, Yang Z, Nussenzweig MC, Bjorkman PJ. Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host & Microbe. 24: 579. DOI: 10.2210/Pdb6Edu/Pdb  0.638
2017 Gristick HB, Wang H, Bjorkman PJ. X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer. Acta Crystallographica. Section D, Structural Biology. 73: 822-828. PMID 28994411 DOI: 10.1107/S2059798317013353  0.595
2017 Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. Elife. 6. PMID 28548638 DOI: 10.7554/Elife.27389  0.64
2017 Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Science Translational Medicine. 9. PMID 28100831 DOI: 10.1126/Scitranslmed.Aal2144  0.584
2017 Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Author response: Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies Elife. DOI: 10.7554/Elife.27389.032  0.591
2016 Wang H, Cohen AA, Galimidi RP, Gristick HB, Jensen GJ, Bjorkman PJ. Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799557 DOI: 10.1073/Pnas.1615939113  0.65
2015 Scharf L, Wang H, Gao H, Chen S, McDowall AW, Bjorkman PJ. Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env. Cell. 162: 1379-90. PMID 26359989 DOI: 10.1016/J.Cell.2015.08.035  0.645
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