Dolph Lee Hatfield - Publications

Affiliations: 
National Cancer Institute National Institutes of Health, Bethesda, MD 
Area:
Molecular Biology of Selenium
Website:
http://dolphhatfield.com/

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Bang J, Kang D, Jung J, Yoo TJ, Shim MS, Gladyshev VN, Tsuji PA, Hatfield DL, Kim JH, Lee BJ. SEPHS1: Its evolution, function and roles in development and diseases. Archives of Biochemistry and Biophysics. 730: 109426. PMID 36202216 DOI: 10.1016/j.abb.2022.109426  0.5
2022 Kang D, Lee J, Jung J, Carlson BA, Chang MJ, Chang CB, Kang SB, Lee BC, Gladyshev VN, Hatfield DL, Lee BJ, Kim JH. Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis. Nature Communications. 13: 779. PMID 35140209 DOI: 10.1038/s41467-022-28385-7  0.463
2021 Tsuji PA, Santesmasses D, Lee BJ, Gladyshev VN, Hatfield DL. Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly. International Journal of Molecular Sciences. 23. PMID 35008430 DOI: 10.3390/ijms23010005  0.459
2021 Bang J, Han M, Yoo TJ, Qiao L, Jung J, Na J, Carlson BA, Gladyshev VN, Hatfield DL, Kim JH, Kim LK, Lee BJ. Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Mice. International Journal of Molecular Sciences. 22. PMID 34769078 DOI: 10.3390/ijms222111647  0.447
2021 Canter JA, Ernst SE, Peters KM, Carlson BA, Thielman NRJ, Grysczyk L, Udofe P, Yu Y, Cao L, Davis CD, Gladyshev VN, Hatfield DL, Tsuji PA. Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity. International Journal of Molecular Sciences. 22. PMID 34638991 DOI: 10.3390/ijms221910651  0.47
2018 Yim SH, Everley RA, Schildberg FA, Lee SG, Orsi A, Barbati ZR, Karatepe K, Fomenko DE, Tsuji PA, Luo HR, Gygi SP, Sitia R, Sharpe AH, Hatfield DL, Gladyshev VN. Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins. Cell Reports. 23: 1387-1398. PMID 29719252 DOI: 10.1016/J.Celrep.2018.04.009  0.534
2018 Na J, Jung J, Bang J, Lu Q, Carlson BA, Guo X, Gladyshev VN, Kim J, Hatfield DL, Lee BJ. Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation. Free Radical Biology & Medicine. PMID 29715549 DOI: 10.1016/J.Freeradbiomed.2018.04.577  0.577
2018 Carlson BA, Lee BJ, Tsuji PA, Copeland PR, Schweizer U, Gladyshev VN, Hatfield DL. Selenocysteine tRNA([Ser]Sec), the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1661: 43-60. PMID 28917036 DOI: 10.1007/978-1-4939-7258-6_4  0.447
2016 Fradejas-Villar N, Seeher S, Anderson CB, Doengi M, Carlson BA, Hatfield DL, Schweizer U, Howard MT. The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay. Nucleic Acids Research. PMID 27956496 DOI: 10.1093/Nar/Gkw1255  0.363
2016 Lobanov AV, Heaphy SM, Turanov AA, Gerashchenko MV, Pucciarelli S, Devaraj RR, Xie F, Petyuk VA, Smith RD, Klobutcher LA, Atkins JF, Miceli C, Hatfield DL, Baranov PV, Gladyshev VN. Position-dependent termination and widespread obligatory frameshifting in Euplotes translation. Nature Structural & Molecular Biology. PMID 27870834 DOI: 10.1038/Nsmb.3330  0.779
2016 Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, ... ... Hatfield DL, et al. Selenoprotein Gene Nomenclature. The Journal of Biological Chemistry. PMID 27645994 DOI: 10.1074/Jbc.M116.756155  0.696
2016 Carlson BA, Tobe R, Yefremova E, Tsuji PA, Hoffmann VJ, Schweizer U, Gladyshev VN, Hatfield DL, Conrad M. Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration. Redox Biology. 9: 22-31. PMID 27262435 DOI: 10.1016/J.Redox.2016.05.003  0.537
2016 Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, ... ... Hatfield DL, et al. Selenophosphate Synthetase 1 is an Essential Protein with Roles in Regulation of Redox Homeostasis in Mammals. The Biochemical Journal. PMID 27208177 DOI: 10.1042/Bcj20160393  0.504
2016 Hatfield DL. Redox Pioneer: Professor Vadim N. Gladyshev. Antioxidants & Redox Signaling. 25: 1-9. PMID 26984707 DOI: 10.1089/Ars.2015.6625  0.326
2016 Schoenmakers E, Carlson B, Agostini M, Moran C, Rajanayagam O, Bochukova E, Tobe R, Peat R, Gevers E, Muntoni F, Guicheney P, Schoenmakers N, Farooqi S, Lyons G, Hatfield D, et al. Mutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis. The Journal of Clinical Investigation. PMID 26854926 DOI: 10.1172/Jci84747  0.319
2015 Tobe R, Carlson BA, Tsuji PA, Lee BJ, Gladyshev VN, Hatfield DL. Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy. Cancers. 7: 2262-76. PMID 26569310 DOI: 10.3390/Cancers7040889  0.407
2015 Turanov AA, Everley RA, Hybsier S, Renko K, Schomburg L, Gygi SP, Hatfield DL, Gladyshev VN. Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine. Plos One. 10: e0140353. PMID 26452064 DOI: 10.1371/Journal.Pone.0140353  0.755
2015 Tsuji PA, Carlson BA, Anderson CB, Seifried HE, Hatfield DL, Howard MT. Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice. Nutrients. 7: 6529-49. PMID 26258789 DOI: 10.3390/Nu7085297  0.382
2015 Mahdi Y, Xu XM, Carlson BA, Fradejas N, Günter P, Braun D, Southon E, Tessarollo L, Hatfield DL, Schweizer U. Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). Plos One. 10: e0127349. PMID 26043259 DOI: 10.1371/Journal.Pone.0127349  0.446
2015 Tsuji PA, Carlson BA, Yoo MH, Naranjo-Suarez S, Xu XM, He Y, Asaki E, Seifried HE, Reinhold WC, Davis CD, Gladyshev VN, Hatfield DL. The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways. Plos One. 10: e0124487. PMID 25886253 DOI: 10.1371/Journal.Pone.0124487  0.532
2015 Bang J, Huh JH, Na JW, Lu Q, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ. Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells. Molecules and Cells. 38: 457-65. PMID 25728752 DOI: 10.14348/Molcells.2015.0007  0.452
2015 Bang J, Jang M, Huh JH, Na JW, Shim M, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ. Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. Biochemical and Biophysical Research Communications. 456: 884-90. PMID 25529450 DOI: 10.1016/J.Bbrc.2014.12.059  0.436
2014 Labunskyy VM, Hatfield DL, Gladyshev VN. Selenoproteins: molecular pathways and physiological roles. Physiological Reviews. 94: 739-77. PMID 24987004 DOI: 10.1152/Physrev.00039.2013  0.782
2014 Turanov AA, Shchedrina VA, Everley RA, Lobanov AV, Yim SH, Marino SM, Gygi SP, Hatfield DL, Gladyshev VN. Selenoprotein S is involved in maintenance and transport of multiprotein complexes. The Biochemical Journal. 462: 555-65. PMID 24897171 DOI: 10.1042/Bj20140076  0.744
2014 Seeher S, Carlson BA, Miniard AC, Wirth EK, Mahdi Y, Hatfield DL, Driscoll DM, Schweizer U. Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice. The Biochemical Journal. 462: 67-75. PMID 24844465 DOI: 10.1042/Bj20140423  0.324
2014 Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE. Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression. The Journal of Biological Chemistry. 289: 15350-62. PMID 24719327 DOI: 10.1074/Jbc.M114.549782  0.74
2014 Wirth EK, Bharathi BS, Hatfield D, Conrad M, Brielmeier M, Schweizer U. Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons. Biological Trace Element Research. 158: 203-10. PMID 24599700 DOI: 10.1007/S12011-014-9920-Z  0.392
2014 Hatfield DL, Tsuji PA, Carlson BA, Gladyshev VN. Selenium and selenocysteine: roles in cancer, health, and development. Trends in Biochemical Sciences. 39: 112-20. PMID 24485058 DOI: 10.1016/J.Tibs.2013.12.007  0.488
2014 Seeher S, Atassi T, Mahdi Y, Carlson BA, Braun D, Wirth EK, Klein MO, Reix N, Miniard AC, Schomburg L, Hatfield DL, Driscoll DM, Schweizer U. Secisbp2 is essential for embryonic development and enhances selenoprotein expression. Antioxidants & Redox Signaling. 21: 835-49. PMID 24274065 DOI: 10.1089/Ars.2013.5358  0.366
2013 Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL. Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus. Plos One. 8: e71427. PMID 24039713 DOI: 10.1371/Journal.Pone.0071427  0.469
2013 Naranjo-Suarez S, Carlson BA, Tobe R, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL. Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status. Molecules and Cells. 36: 151-7. PMID 23912593 DOI: 10.1007/S10059-013-0121-Y  0.489
2013 Turanov AA, Lobanov AV, Hatfield DL, Gladyshev VN. UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins. Nucleic Acids Research. 41: 6952-9. PMID 23716634 DOI: 10.1093/Nar/Gkt409  0.727
2013 Patterson AD, Carlson BA, Li F, Bonzo JA, Yoo MH, Krausz KW, Conrad M, Chen C, Gonzalez FJ, Hatfield DL. Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. Chemical Research in Toxicology. 26: 1088-96. PMID 23697945 DOI: 10.1021/Tx4001013  0.356
2013 Howard MT, Carlson BA, Anderson CB, Hatfield DL. Translational redefinition of UGA codons is regulated by selenium availability. The Journal of Biological Chemistry. 288: 19401-13. PMID 23696641 DOI: 10.1074/Jbc.M113.481051  0.406
2013 Tobe R, Naranjo-Suarez S, Everley RA, Carlson BA, Turanov AA, Tsuji PA, Yoo MH, Gygi SP, Gladyshev VN, Hatfield DL. High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin. The Journal of Biological Chemistry. 288: 14709-15. PMID 23589299 DOI: 10.1074/Jbc.M112.446666  0.734
2013 Moustafa ME, Carlson BA, Anver MR, Bobe G, Zhong N, Ward JM, Perella CM, Hoffmann VJ, Rogers K, Combs GF, Schweizer U, Merlino G, Gladyshev VN, Hatfield DL. Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα. Plos One. 8: e57389. PMID 23460847 DOI: 10.1371/Journal.Pone.0057389  0.531
2013 Kasaikina MV, Turanov AA, Avanesov A, Schweizer U, Seeher S, Bronson RT, Novoselov SN, Carlson BA, Hatfield DL, Gladyshev VN. Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis. Carcinogenesis. 34: 1089-95. PMID 23389288 DOI: 10.1093/Carcin/Bgt011  0.785
2013 Sengupta A, Lichti UF, Carlson BA, Cataisson C, Ryscavage AO, Mikulec C, Conrad M, Fischer SM, Hatfield DL, Yuspa SH. Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2. The Journal of Investigative Dermatology. 133: 1731-41. PMID 23364477 DOI: 10.1038/Jid.2013.52  0.32
2012 Tsuji PA, Carlson BA, Naranjo-Suarez S, Yoo MH, Xu XM, Fomenko DE, Gladyshev VN, Hatfield DL, Davis CD. Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice. Plos One. 7: e50574. PMID 23226526 DOI: 10.1371/Journal.Pone.0050574  0.548
2012 Carlson BA, Yoo MH, Tobe R, Mueller C, Naranjo-Suarez S, Hoffmann VJ, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis. Carcinogenesis. 33: 1806-13. PMID 22791808 DOI: 10.1093/Carcin/Bgs230  0.532
2012 Tobe R, Yoo MH, Fradejas N, Carlson BA, Calvo S, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism. The Biochemical Journal. 445: 423-30. PMID 22594686 DOI: 10.1042/Bj20120618  0.511
2012 Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN. Composition and evolution of the vertebrate and mammalian selenoproteomes. Plos One. 7: e33066. PMID 22479358 DOI: 10.1371/Journal.Pone.0033066  0.548
2012 Kasaikina MV, Hatfield DL, Gladyshev VN. Understanding selenoprotein function and regulation through the use of rodent models. Biochimica Et Biophysica Acta. 1823: 1633-42. PMID 22440326 DOI: 10.1016/J.Bbamcr.2012.02.018  0.796
2012 Hudson TS, Carlson BA, Hoeneroff MJ, Young HA, Sordillo L, Muller WJ, Hatfield DL, Green JE. Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis. Carcinogenesis. 33: 1225-30. PMID 22436612 DOI: 10.1093/Carcin/Bgs129  0.354
2012 Naranjo-Suarez S, Carlson BA, Tsuji PA, Yoo MH, Gladyshev VN, Hatfield DL. HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia. Plos One. 7: e30470. PMID 22348009 DOI: 10.1371/Journal.Pone.0030470  0.51
2012 Malinouski M, Kehr S, Finney L, Vogt S, Carlson BA, Seravalli J, Jin R, Handy DE, Park TJ, Loscalzo J, Hatfield DL, Gladyshev VN. High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3. Antioxidants & Redox Signaling. 16: 185-92. PMID 21854231 DOI: 10.1089/Ars.2011.3997  0.781
2011 Turanov AA, Xu XM, Carlson BA, Yoo MH, Gladyshev VN, Hatfield DL. Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis. Advances in Nutrition (Bethesda, Md.). 2: 122-8. PMID 22332041 DOI: 10.3945/An.110.000265  0.758
2011 Shchedrina VA, Everley RA, Zhang Y, Gygi SP, Hatfield DL, Gladyshev VN. Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis. The Journal of Biological Chemistry. 286: 42937-48. PMID 22016385 DOI: 10.1074/Jbc.M111.310920  0.534
2011 Carlson BA, Yoo MH, Conrad M, Gladyshev VN, Hatfield DL, Park JM. Protein kinase-regulated expression and immune function of thioredoxin reductase 1 in mouse macrophages. Molecular Immunology. 49: 311-6. PMID 21943784 DOI: 10.1016/J.Molimm.2011.09.001  0.531
2011 Lee KH, Shim MS, Kim JY, Jung HK, Lee E, Carlson BA, Xu XM, Park JM, Hatfield DL, Park T, Lee BJ. Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation. Bmc Genomics. 12: 426. PMID 21864351 DOI: 10.1186/1471-2164-12-426  0.343
2011 Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, ... ... Hatfield DL, et al. Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice. The Journal of Biological Chemistry. 286: 33203-12. PMID 21768092 DOI: 10.1074/Jbc.M111.259218  0.785
2011 Kim JY, Carlson BA, Xu XM, Zeng Y, Chen S, Gladyshev VN, Lee BJ, Hatfield DL. Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA. Biochemical and Biophysical Research Communications. 409: 814-9. PMID 21624347 DOI: 10.1016/J.Bbrc.2011.05.096  0.519
2011 Shchedrina VA, Kabil H, Vorbruggen G, Lee BC, Turanov AA, Hirosawa-Takamori M, Kim HY, Harshman LG, Hatfield DL, Gladyshev VN. Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of selenoproteins in stress resistance. The Journal of Biological Chemistry. 286: 29449-61. PMID 21622567 DOI: 10.1074/Jbc.M111.257600  0.758
2011 Kasaikina MV, Kravtsova MA, Lee BC, Seravalli J, Peterson DA, Walter J, Legge R, Benson AK, Hatfield DL, Gladyshev VN. Dietary selenium affects host selenoproteome expression by influencing the gut microbiota. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2492-9. PMID 21493887 DOI: 10.1096/Fj.11-181990  0.788
2011 Lee BC, Lobanov AV, Marino SM, Kaya A, Seravalli J, Hatfield DL, Gladyshev VN. A 4-selenocysteine, 2-selenocysteine insertion sequence (SECIS) element methionine sulfoxide reductase from Metridium senile reveals a non-catalytic function of selenocysteines. The Journal of Biological Chemistry. 286: 18747-55. PMID 21393246 DOI: 10.1074/Jbc.M111.229807  0.674
2011 Kasaikina MV, Lobanov AV, Malinouski MY, Lee BC, Seravalli J, Fomenko DE, Turanov AA, Finney L, Vogt S, Park TJ, Miller RA, Hatfield DL, Gladyshev VN. Reduced utilization of selenium by naked mole rats due to a specific defect in GPx1 expression. The Journal of Biological Chemistry. 286: 17005-14. PMID 21372135 DOI: 10.1074/Jbc.M110.216267  0.78
2011 Malinouski M, Zhou Y, Belousov VV, Hatfield DL, Gladyshev VN. Hydrogen peroxide probes directed to different cellular compartments. Plos One. 6: e14564. PMID 21283738 DOI: 10.1371/Journal.Pone.0014564  0.774
2011 Labunskyy VM, Lee BC, Handy DE, Loscalzo J, Hatfield DL, Gladyshev VN. Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice. Antioxidants & Redox Signaling. 14: 2327-36. PMID 21194350 DOI: 10.1089/Ars.2010.3526  0.743
2011 Tsuji PA, Carlson BA, Yoo M, Xu X, Naranjo-Suarez S, Fomenko D, Gladyshev VN, Hatfield DL, Davis CD. Abstract 1868: Sep15 knockout in mice provides protection against chemically-induced aberrant crypt formation Cancer Research. 71: 1868-1868. DOI: 10.1158/1538-7445.Am2011-1868  0.541
2010 Xu XM, Turanov AA, Carlson BA, Yoo MH, Everley RA, Nandakumar R, Sorokina I, Gygi SP, Gladyshev VN, Hatfield DL. Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery. Proceedings of the National Academy of Sciences of the United States of America. 107: 21430-4. PMID 21115847 DOI: 10.1073/Pnas.1009947107  0.786
2010 Sengupta A, Lichti UF, Carlson BA, Ryscavage AO, Gladyshev VN, Yuspa SH, Hatfield DL. Selenoproteins are essential for proper keratinocyte function and skin development. Plos One. 5: e12249. PMID 20805887 DOI: 10.1371/Journal.Pone.0012249  0.455
2010 Yoo MH, Carlson BA, Tsuji P, Irons R, Gladyshev VN, Hatfield DL. Alteration of thioredoxin reductase 1 levels in elucidating cancer etiology. Methods in Enzymology. 474: 255-75. PMID 20609915 DOI: 10.1016/S0076-6879(10)74015-5  0.493
2010 Turanov AA, Hatfield DL, Gladyshev VN. Characterization of protein targets of mammalian thioredoxin reductases. Methods in Enzymology. 474: 245-54. PMID 20609914 DOI: 10.1016/S0076-6879(10)74014-3  0.733
2010 Carlson BA, Yoo MH, Shrimali RK, Irons R, Gladyshev VN, Hatfield DL, Park JM. Role of selenium-containing proteins in T-cell and macrophage function. The Proceedings of the Nutrition Society. 69: 300-10. PMID 20576203 DOI: 10.1017/S002966511000176X  0.476
2010 Turanov AA, Kehr S, Marino SM, Yoo MH, Carlson BA, Hatfield DL, Gladyshev VN. Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets. The Biochemical Journal. 430: 285-93. PMID 20536427 DOI: 10.1042/Bj20091378  0.771
2010 Kim JY, Lee KH, Shim MS, Shin H, Xu XM, Carlson BA, Hatfield DL, Lee BJ. Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns. Biochemical and Biophysical Research Communications. 397: 53-8. PMID 20471958 DOI: 10.1016/J.Bbrc.2010.05.055  0.342
2010 Lobanov AV, Turanov AA, Hatfield DL, Gladyshev VN. Dual functions of codons in the genetic code. Critical Reviews in Biochemistry and Molecular Biology. 45: 257-65. PMID 20446809 DOI: 10.3109/10409231003786094  0.735
2010 Irons R, Tsuji PA, Carlson BA, Ouyang P, Yoo MH, Xu XM, Hatfield DL, Gladyshev VN, Davis CD. Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 630-9. PMID 20388823 DOI: 10.1158/1940-6207.Capr-10-0003  0.515
2010 Wirth EK, Conrad M, Winterer J, Wozny C, Carlson BA, Roth S, Schmitz D, Bornkamm GW, Coppola V, Tessarollo L, Schomburg L, Köhrle J, Hatfield DL, Schweizer U. Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 844-52. PMID 19890015 DOI: 10.1096/Fj.09-143974  0.307
2010 Yoo MH, Gu X, Xu XM, Kim JY, Carlson BA, Patterson AD, Cai H, Gladyshev VN, Hatfield DL. Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease. Antioxidants & Redox Signaling. 12: 819-27. PMID 19769463 DOI: 10.1089/Ars.2009.2891  0.508
2010 Novoselov SV, Kim HY, Hua D, Lee BC, Astle CM, Harrison DE, Friguet B, Moustafa ME, Carlson BA, Hatfield DL, Gladyshev VN. Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice. Antioxidants & Redox Signaling. 12: 829-38. PMID 19769460 DOI: 10.1089/Ars.2009.2895  0.547
2010 Shchedrina VA, Zhang Y, Labunskyy VM, Hatfield DL, Gladyshev VN. Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins. Antioxidants & Redox Signaling. 12: 839-49. PMID 19747065 DOI: 10.1089/Ars.2009.2865  0.77
2009 Sengupta A, Carlson BA, Labunskyy VM, Gladyshev VN, Hatfield DL. Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 953-61. PMID 19935881 DOI: 10.1139/o09-064  0.77
2009 Carlson BA, Yoo MH, Sano Y, Sengupta A, Kim JY, Irons R, Gladyshev VN, Hatfield DL, Park JM. Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression. Bmc Immunology. 10: 57. PMID 19863805 DOI: 10.1186/1471-2172-10-57  0.55
2009 Carlson BA, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL. Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development. Molecules (Basel, Switzerland). 14: 3509-27. PMID 19783940 DOI: 10.3390/Molecules14093509  0.58
2009 Shim MS, Kim JY, Jung HK, Lee KH, Xu XM, Carlson BA, Kim KW, Kim IY, Hatfield DL, Lee BJ. Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. The Journal of Biological Chemistry. 284: 32881-94. PMID 19755423 DOI: 10.1074/Jbc.M109.026492  0.344
2009 Xu XM, Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL. Simultaneous knockdown of the expression of two genes using multiple shRNAs and subsequent knock-in of their expression. Nature Protocols. 4: 1338-48. PMID 19713955 DOI: 10.1038/Nprot.2009.145  0.505
2009 Downey CM, Horton CR, Carlson BA, Parsons TE, Hatfield DL, Hallgrímsson B, Jirik FR. Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease. Plos Genetics. 5: e1000616. PMID 19696890 DOI: 10.1371/Journal.Pgen.1000616  0.36
2009 Labunskyy VM, Yoo MH, Hatfield DL, Gladyshev VN. Sep15, a thioredoxin-like selenoprotein, is involved in the unfolded protein response and differentially regulated by adaptive and acute ER stresses. Biochemistry. 48: 8458-65. PMID 19650649 DOI: 10.1021/Bi900717P  0.764
2009 Lobanov AV, Hatfield DL, Gladyshev VN. Eukaryotic selenoproteins and selenoproteomes. Biochimica Et Biophysica Acta. 1790: 1424-8. PMID 19477234 DOI: 10.1016/J.Bbagen.2009.05.014  0.539
2009 Kehr S, Malinouski M, Finney L, Vogt S, Labunskyy VM, Kasaikina MV, Carlson BA, Zhou Y, Hatfield DL, Gladyshev VN. X-ray fluorescence microscopy reveals the role of selenium in spermatogenesis. Journal of Molecular Biology. 389: 808-18. PMID 19379757 DOI: 10.1016/J.Jmb.2009.04.024  0.762
2009 Hatfield DL, Gladyshev VN. The Outcome of Selenium and Vitamin E Cancer Prevention Trial (SELECT) reveals the need for better understanding of selenium biology. Molecular Interventions. 9: 18-21. PMID 19299660 DOI: 10.1124/Mi.9.1.6  0.464
2009 Hatfield DL, Yoo MH, Carlson BA, Gladyshev VN. Selenoproteins that function in cancer prevention and promotion. Biochimica Et Biophysica Acta. 1790: 1541-5. PMID 19272412 DOI: 10.1016/J.Bbagen.2009.03.001  0.485
2009 Turanov AA, Lobanov AV, Fomenko DE, Morrison HG, Sogin ML, Klobutcher LA, Hatfield DL, Gladyshev VN. Genetic code supports targeted insertion of two amino acids by one codon. Science (New York, N.Y.). 323: 259-61. PMID 19131629 DOI: 10.1126/Science.1164748  0.736
2009 Fomenko DE, Novoselov SV, Natarajan SK, Lee BC, Koc A, Carlson BA, Lee TH, Kim HY, Hatfield DL, Gladyshev VN. MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form. The Journal of Biological Chemistry. 284: 5986-93. PMID 18990697 DOI: 10.1074/Jbc.M805770200  0.589
2009 Carlson BA, Schweizer U, Perella C, Shrimali RK, Feigenbaum L, Shen L, Speransky S, Floss T, Jeong SJ, Watts J, Hoffmann V, Combs GF, Gladyshev VN, Hatfield DL. The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice. The Biochemical Journal. 418: 61-71. PMID 18973473 DOI: 10.1042/Bj20081304  0.563
2008 Zhang Y, Turanov AA, Hatfield DL, Gladyshev VN. In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait. Bmc Genomics. 9: 251. PMID 18510720 DOI: 10.1186/1471-2164-9-251  0.758
2008 Le DT, Liang X, Fomenko DE, Raza AS, Chong CK, Carlson BA, Hatfield DL, Gladyshev VN. Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms. Biochemistry. 47: 6685-94. PMID 18505275 DOI: 10.1021/Bi800422S  0.51
2008 Shrimali RK, Irons RD, Carlson BA, Sano Y, Gladyshev VN, Park JM, Hatfield DL. Selenoproteins mediate T cell immunity through an antioxidant mechanism. The Journal of Biological Chemistry. 283: 20181-5. PMID 18487203 DOI: 10.1074/Jbc.M802559200  0.509
2008 Lobanov AV, Hatfield DL, Gladyshev VN. Reduced reliance on the trace element selenium during evolution of mammals Genome Biology. 9. PMID 18377657 DOI: 10.1186/Gb-2008-9-3-R62  0.552
2008 Sengupta A, Carlson BA, Weaver JA, Novoselov SV, Fomenko DE, Gladyshev VN, Hatfield DL. A functional link between housekeeping selenoproteins and phase II enzymes. The Biochemical Journal. 413: 151-61. PMID 18373496 DOI: 10.1042/Bj20080277  0.551
2008 Lobanov AV, Hatfield DL, Gladyshev VN. Selenoproteinless animals: Selenophosphate synthetase SPS1 functions in a pathway unrelated to selenocysteine biosynthesis Protein Science. 17: 176-182. PMID 18156471 DOI: 10.1110/Ps.073261508  0.555
2008 Ganichkin OM, Xu XM, Carlson BA, Mix H, Hatfield DL, Gladyshev VN, Wahl MC. Structure and catalytic mechanism of eukaryotic selenocysteine synthase. The Journal of Biological Chemistry. 283: 5849-65. PMID 18093968 DOI: 10.1074/Jbc.M709342200  0.491
2008 Zhang Y, Zhou Y, Schweizer U, Savaskan NE, Hua D, Kipnis J, Hatfield DL, Gladyshev VN. Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammals. The Journal of Biological Chemistry. 283: 2427-38. PMID 18032379 DOI: 10.1074/Jbc.M707951200  0.499
2008 Sengupta A, Carlson BA, Hoffmann VJ, Gladyshev VN, Hatfield DL. Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolism. Biochemical and Biophysical Research Communications. 365: 446-52. PMID 17996733 DOI: 10.1016/J.Bbrc.2007.10.189  0.563
2007 Yoo MH, Xu XM, Carlson BA, Patterson AD, Gladyshev VN, Hatfield DL. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. Plos One. 2: e1112. PMID 17971875 DOI: 10.1371/Journal.Pone.0001112  0.495
2007 Xu XM, Carlson BA, Zhang Y, Mix H, Kryukov GV, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL. New developments in selenium biochemistry: selenocysteine biosynthesis in eukaryotes and archaea. Biological Trace Element Research. 119: 234-41. PMID 17916946 DOI: 10.1007/S12011-007-8003-9  0.695
2007 Lobanov AV, Fomenko DE, Zhang Y, Sengupta A, Hatfield DL, Gladyshev VN. Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life. Genome Biology. 8: R198. PMID 17880704 DOI: 10.1186/Gb-2007-8-9-R198  0.477
2007 Carlson BA, Moustafa ME, Sengupta A, Schweizer U, Shrimali R, Rao M, Zhong N, Wang S, Feigenbaum L, Lee BJ, Gladyshev VN, Hatfield DL. Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34. The Journal of Biological Chemistry. 282: 32591-602. PMID 17848557 DOI: 10.1074/Jbc.M707036200  0.52
2007 Sheridan PA, Zhong N, Carlson BA, Perella CM, Hatfield DL, Beck MA. Decreased selenoprotein expression alters the immune response during influenza virus infection in mice. The Journal of Nutrition. 137: 1466-71. PMID 17513408 DOI: 10.1093/Jn/137.6.1466  0.308
2007 Dikiy A, Novoselov SV, Fomenko DE, Sengupta A, Carlson BA, Cerny RL, Ginalski K, Grishin NV, Hatfield DL, Gladyshev VN. SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family. Biochemistry. 46: 6871-82. PMID 17503775 DOI: 10.1021/Bi602462Q  0.551
2007 Novoselov SV, Lobanov AV, Hua D, Kasaikina MV, Hatfield DL, Gladyshev VN. A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 7857-62. PMID 17470795 DOI: 10.1073/Pnas.0610683104  0.793
2007 Yoo MH, Xu XM, Turanov AA, Carlson BA, Gladyshev VN, Hatfield DL. A new strategy for assessing selenoprotein function: siRNA knockdown/knock-in targeting the 3'-UTR. Rna (New York, N.Y.). 13: 921-9. PMID 17468436 DOI: 10.1261/Rna.533007  0.763
2007 Labunskyy VM, Hatfield DL, Gladyshev VN. The Sep15 protein family: roles in disulfide bond formation and quality control in the endoplasmic reticulum. Iubmb Life. 59: 1-5. PMID 17365173 DOI: 10.1080/15216540601126694  0.753
2007 Xu XM, Carlson BA, Irons R, Mix H, Zhong N, Gladyshev VN, Hatfield DL. Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis. The Biochemical Journal. 404: 115-20. PMID 17346238 DOI: 10.1042/Bj20070165  0.547
2007 Novoselov SV, Kryukov GV, Xu XM, Carlson BA, Hatfield DL, Gladyshev VN. Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern. The Journal of Biological Chemistry. 282: 11960-8. PMID 17337453 DOI: 10.1074/Jbc.M701605200  0.733
2007 Xu XM, Carlson BA, Mix H, Zhang Y, Saira K, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL. Biosynthesis of selenocysteine on its tRNA in eukaryotes. Plos Biology. 5: e4. PMID 17194211 DOI: 10.1371/Journal.Pbio.0050004  0.471
2007 Shrimali RK, Weaver JA, Miller GF, Starost MF, Carlson BA, Novoselov SV, Kumaraswamy E, Gladyshev VN, Hatfield DL. Selenoprotein expression is essential in endothelial cell development and cardiac muscle function. Neuromuscular Disorders : Nmd. 17: 135-42. PMID 17142041 DOI: 10.1016/J.Nmd.2006.10.006  0.505
2007 Turanov A, Kehr S, Carlson BA, Hatfield DL, Gladyshev VN. Mammalian thioredoxin reductases: roles in redox homeostasis and analysis of cellular targets The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A718-C  0.726
2007 Labunskyy VM, Fomenko DE, Shrimali RK, Hatfield DL, Gladyshev VN. Expression of Sep15, a thioredoxin‐like selenoprotein, is induced in response to accumulation of unfolded proteins in the endoplasmic reticulum The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A115-A  0.51
2007 Yoo M, Xu X, Carlson BA, Gladyshev VN, Hatfield DL. Examination of anticancer mechanisms in ras‐induced cancer cells by targeting thioredoxin reductase 1 knockdown The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A115  0.467
2007 Sengupta A, Carlson BA, Hoffmann VJ, Gladyshev VN, Hatfield DL. Conditional knockout of selenocysteine tRNA gene ( trsp ) in liver modulates lipoprotein metabolism The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A114  0.486
2007 Lobanov A, Castellano S, Hatfield DL, Gladyshev VN. Reduced utilization of selenium during evolution of mammals The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A105-E  0.477
2006 Chen CL, Shim MS, Chung J, Yoo HS, Ha JM, Kim JY, Choi J, Zang SL, Hou X, Carlson BA, Hatfield DL, Lee BJ. G-rich, a Drosophila selenoprotein, is a Golgi-resident type III membrane protein. Biochemical and Biophysical Research Communications. 348: 1296-301. PMID 16920070 DOI: 10.1016/J.Bbrc.2006.07.203  0.304
2006 Hatfield DL, Carlson BA, Xu XM, Mix H, Gladyshev VN. Selenocysteine incorporation machinery and the role of selenoproteins in development and health. Progress in Nucleic Acid Research and Molecular Biology. 81: 97-142. PMID 16891170 DOI: 10.1016/S0079-6603(06)81003-2  0.544
2006 Lobanov AV, Kryukov GV, Hatfield DL, Gladyshev VN. Is there a twenty third amino acid in the genetic code? Trends in Genetics : Tig. 22: 357-60. PMID 16713651 DOI: 10.1016/J.Tig.2006.05.002  0.669
2006 Irons R, Carlson BA, Hatfield DL, Davis CD. Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression. The Journal of Nutrition. 136: 1311-7. PMID 16614422 DOI: 10.1093/Jn/136.5.1311  0.356
2006 Yoo MH, Xu XM, Carlson BA, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells. The Journal of Biological Chemistry. 281: 13005-8. PMID 16565519 DOI: 10.1074/Jbc.C600012200  0.526
2006 Small-Howard A, Morozova N, Stoytcheva Z, Forry EP, Mansell JB, Harney JW, Carlson BA, Xu XM, Hatfield DL, Berry MJ. Supramolecular complexes mediate selenocysteine incorporation in vivo. Molecular and Cellular Biology. 26: 2337-46. PMID 16508009 DOI: 10.1128/Mcb.26.6.2337-2346.2006  0.348
2006 Lobanov AV, Delgado C, Rahlfs S, Novoselov SV, Kryukov GV, Gromer S, Hatfield DL, Becker K, Gladyshev VN. The Plasmodium selenoproteome. Nucleic Acids Research. 34: 496-505. PMID 16428245 DOI: 10.1093/Nar/Gkj450  0.703
2005 Sun QA, Su D, Novoselov SV, Carlson BA, Hatfield DL, Gladyshev VN. Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase. Biochemistry. 44: 14528-37. PMID 16262253 DOI: 10.1021/Bi051321W  0.741
2005 Xu XM, Mix H, Carlson BA, Grabowski PJ, Gladyshev VN, Berry MJ, Hatfield DL. Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery. The Journal of Biological Chemistry. 280: 41568-75. PMID 16230358 DOI: 10.1074/Jbc.M506696200  0.581
2005 Novoselov SV, Calvisi DF, Labunskyy VM, Factor VM, Carlson BA, Fomenko DE, Moustafa ME, Hatfield DL, Gladyshev VN. Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice. Oncogene. 24: 8003-11. PMID 16170372 DOI: 10.1038/Sj.Onc.1208940  0.761
2005 Labunskyy VM, Ferguson AD, Fomenko DE, Chelliah Y, Hatfield DL, Gladyshev VN. A novel cysteine-rich domain of Sep15 mediates the interaction with UDP-glucose:glycoprotein glucosyltransferase. The Journal of Biological Chemistry. 280: 37839-45. PMID 16129668 DOI: 10.1074/Jbc.M508685200  0.759
2005 Su D, Novoselov SV, Sun QA, Moustafa ME, Zhou Y, Oko R, Hatfield DL, Gladyshev VN. Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation. The Journal of Biological Chemistry. 280: 26491-8. PMID 15901730 DOI: 10.1074/Jbc.M503638200  0.751
2005 Shrimali RK, Lobanov AV, Xu XM, Rao M, Carlson BA, Mahadeo DC, Parent CA, Gladyshev VN, Hatfield DL. Selenocysteine tRNA identification in the model organisms Dictyostelium discoideum and Tetrahymena thermophila. Biochemical and Biophysical Research Communications. 329: 147-51. PMID 15721286 DOI: 10.1016/J.Bbrc.2005.01.120  0.518
2005 Schweizer U, Streckfuss F, Pelt P, Carlson BA, Hatfield DL, Köhrle J, Schomburg L. Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply. The Biochemical Journal. 386: 221-6. PMID 15638810 DOI: 10.1042/Bj20041973  0.338
2005 Carlson BA, Xu XM, Gladyshev VN, Hatfield DL. Selective rescue of selenoprotein expression in mice lacking a highly specialized methyl group in selenocysteine tRNA. The Journal of Biological Chemistry. 280: 5542-8. PMID 15611090 DOI: 10.1074/Jbc.M411725200  0.591
2004 Carlson BA, Xu XM, Kryukov GV, Rao M, Berry MJ, Gladyshev VN, Hatfield DL. Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase. Proceedings of the National Academy of Sciences of the United States of America. 101: 12848-53. PMID 15317934 DOI: 10.1073/Pnas.0402636101  0.7
2004 Gladyshev VN, Kryukov GV, Fomenko DE, Hatfield DL. Identification of trace element-containing proteins in genomic databases. Annual Review of Nutrition. 24: 579-96. PMID 15189132 DOI: 10.1146/Annurev.Nutr.24.012003.132241  0.693
2004 Jin JS, Baek S, Lee H, Oh MY, Koo YE, Shim MS, Kwon SY, Jeon I, Park SY, Baek K, Yoo MA, Hatfield DL, Lee BJ. A DNA replication-related element downstream from the initiation site of Drosophila selenophosphate synthetase 2 gene is essential for its transcription. Nucleic Acids Research. 32: 2482-93. PMID 15121905 DOI: 10.1093/Nar/Gkh569  0.609
2004 Carlson BA, Novoselov SV, Kumaraswamy E, Lee BJ, Anver MR, Gladyshev VN, Hatfield DL. Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function. The Journal of Biological Chemistry. 279: 8011-7. PMID 14660662 DOI: 10.1074/Jbc.M310470200  0.478
2003 Kwon SY, Badenhorst P, Martin-Romero FJ, Carlson BA, Paterson BM, Gladyshev VN, Lee BJ, Hatfield DL. The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development. Molecular and Cellular Biology. 23: 8495-504. PMID 14612395 DOI: 10.1128/Mcb.23.23.8495-8504.2003  0.808
2003 Hornberger TA, McLoughlin TJ, Leszczynski JK, Armstrong DD, Jameson RR, Bowen PE, Hwang ES, Hou H, Moustafa ME, Carlson BA, Hatfield DL, Diamond AM, Esser KA. Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth. The Journal of Nutrition. 133: 3091-7. PMID 14519790 DOI: 10.1093/Jn/133.10.3091  0.306
2003 Rao M, Carlson BA, Novoselov SV, Weeks DP, Gladyshev VN, Hatfield DL. Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec. Rna (New York, N.Y.). 9: 923-30. PMID 12869703 DOI: 10.1261/Rna.5510503  0.529
2003 Moustafa ME, Kumaraswamy E, Zhong N, Rao M, Carlson BA, Hatfield DL. Models for assessing the role of selenoproteins in health. The Journal of Nutrition. 133: 2494S-2496S. PMID 12840229 DOI: 10.1093/Jn/133.7.2494S  0.353
2003 Kim M, Choi J, Carlson BA, Han JK, Rhee K, Sargent T, Hatfield DL, Lee BJ. A novel TBP-interacting zinc finger protein functions in early development of Xenopus laevis. Biochemical and Biophysical Research Communications. 306: 1106-11. PMID 12821157 DOI: 10.1016/S0006-291X(03)01069-6  0.345
2003 Kim M, Park CH, Lee MS, Carlson BA, Hatfield DL, Lee BJ. A novel TBP-interacting zinc finger protein represses transcription by inhibiting the recruitment of TFIIA and TFIIB. Biochemical and Biophysical Research Communications. 306: 231-8. PMID 12788093 DOI: 10.1016/S0006-291X(03)00939-2  0.323
2003 Kumaraswamy E, Carlson BA, Morgan F, Miyoshi K, Robinson GW, Su D, Wang S, Southon E, Tessarollo L, Lee BJ, Gladyshev VN, Hennighausen L, Hatfield DL. Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Molecular and Cellular Biology. 23: 1477-88. PMID 12588969 DOI: 10.1128/Mcb.23.5.1477-1488.2003  0.686
2002 Xu XM, Carlson BA, Grimm TA, Kutza J, Berry MJ, Arreola R, Fields KH, Shanmugam I, Jeang KT, Oroszlan S, Combs GF, Marx PA, Gladyshev VN, Clouse KA, Hatfield DL. Rhesus monkey simian immunodeficiency virus infection as a model for assessing the role of selenium in AIDS. Journal of Acquired Immune Deficiency Syndromes (1999). 31: 453-63. PMID 12473832 DOI: 10.1097/00126334-200212150-00001  0.402
2002 Novoselov SV, Rao M, Onoshko NV, Zhi H, Kryukov GV, Xiang Y, Weeks DP, Hatfield DL, Gladyshev VN. Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii. The Embo Journal. 21: 3681-93. PMID 12110581 DOI: 10.1093/Emboj/Cdf372  0.691
2002 Jameson RR, Carlson BA, Butz M, Esser K, Hatfield DL, Diamond AM. Selenium influences the turnover of selenocysteine tRNA([Ser]Sec) in Chinese hamster ovary cells. The Journal of Nutrition. 132: 1830-5. PMID 12097655 DOI: 10.1093/Jn/132.7.1830  0.405
2002 Hatfield DL, Gladyshev VN. How selenium has altered our understanding of the genetic code Molecular and Cellular Biology. 22: 3565-3576. PMID 11997494 DOI: 10.1128/Mcb.22.11.3565-3576.2002  0.558
2002 Kumaraswamy E, Korotkov KV, Diamond AM, Gladyshev VN, Hatfield DL. Genetic and functional analysis of mammalian Sep15 selenoprotein. Methods in Enzymology. 347: 187-97. PMID 11898406 DOI: 10.1016/S0076-6879(02)47017-6  0.455
2002 Korotkov KV, Novoselov SV, Hatfield DL, Gladyshev VN. Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element Molecular and Cellular Biology. 22: 1402-1411. PMID 11839807 DOI: 10.1128/Mcb.22.5.1402-1411.2002  0.569
2001 Moustafa ME, Carlson BA, El-Saadani MA, Kryukov GV, Sun QA, Harney JW, Hill KE, Combs GF, Feigenbaum L, Mansur DB, Burk RF, Berry MJ, Diamond AM, Lee BJ, Gladyshev VN, ... Hatfield DL, et al. Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA. Molecular and Cellular Biology. 21: 3840-52. PMID 11340175 DOI: 10.1128/Mcb.21.11.3840-3852.2001  0.787
2001 Korotkov KV, Kumaraswamy E, Zhou Y, Hatfield DL, Gladyshev VN. Association between the 15-kDa Selenoprotein and UDP-glucose:Glycoprotein Glucosyltransferase in the Endoplasmic Reticulum of Mammalian Cells Journal of Biological Chemistry. 276: 15330-15336. PMID 11278576 DOI: 10.1074/Jbc.M009861200  0.558
2001 Carlson BA, Mushinski JF, Henderson DW, Kwon SY, Crain PF, Lee BJ, Hatfield DL. 1-Methylguanosine in place of Y base at position 37 in phenylalanine tRNA is responsible for its shiftiness in retroviral ribosomal frameshifting. Virology. 279: 130-5. PMID 11145896 DOI: 10.1006/Viro.2000.0692  0.576
2000 Tujebajeva RM, Copeland PR, Xu XM, Carlson BA, Harney JW, Driscoll DM, Hatfield DL, Berry MJ. Decoding apparatus for eukaryotic selenocysteine insertion. Embo Reports. 1: 158-63. PMID 11265756 DOI: 10.1093/Embo-Reports/Kvd033  0.381
2000 Kumaraswamy E, Malykh A, Korotkov KV, Kozyavkin S, Hu Y, Kwon SY, Moustafa ME, Carlson BA, Berry MJ, Lee BJ, Hatfield DL, Diamond AM, Gladyshev VN. Structure-expression relationships of the 15-kDa selenoprotein gene. Possible role of the protein in cancer etiology. The Journal of Biological Chemistry. 275: 35540-7. PMID 10945981 DOI: 10.1074/Jbc.M004014200  0.679
2000 Mansur DB, Hao H, Gladyshev VN, Korotkov KV, Hu Y, Moustafa ME, El-Saadani MA, Carlson BA, Hatfield DL, Diamond AM. Multiple levels of regulation of selenoprotein biosynthesis revealed from the analysis of human glioma cell lines. Biochemical Pharmacology. 60: 489-97. PMID 10874123 DOI: 10.1016/S0006-2952(00)00366-X  0.526
2000 Carlson BA, Kwon SY, Lee BJ, Hatfield D. Yeast asparagine (Asn) tRNA without Q base promotes eukaryotic frameshifting more efficiently than mammalian Asn tRNAs with or without Q base. Molecules and Cells. 10: 113-8. PMID 10774757 DOI: 10.1007/S10059-000-0113-6  0.557
2000 Copeland PR, Fletcher JE, Carlson BA, Hatfield DL, Driscoll DM. A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs. The Embo Journal. 19: 306-14. PMID 10637234 DOI: 10.1093/Emboj/19.2.306  0.371
1999 Xu XM, Carlson BA, Kim LK, Lee BJ, Hatfield DL, Diamond AM. Analysis of selenocysteine (Sec) tRNA([Ser]Sec) genes in Chinese hamsters. Gene. 239: 49-53. PMID 10571033 DOI: 10.1016/S0378-1119(99)00382-0  0.35
1999 Harris LF, Sullivan MR, Hatfield DL. Directed molecular evolution. Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life. 29: 425-35. PMID 10472630 DOI: 10.1023/A:1006683409144  0.308
1999 Xu XM, Zhou X, Carlson BA, Kim LK, Huh TL, Lee BJ, Hatfield DL. The zebrafish genome contains two distinct selenocysteine tRNA[Ser]sec genes. Febs Letters. 454: 16-20. PMID 10413087 DOI: 10.1016/S0014-5793(99)00767-X  0.329
1999 Gladyshev VN, Hatfield DL. Selenocysteine-containing proteins in mammals Journal of Biomedical Science. 6: 151-160. PMID 10343164 DOI: 10.1007/Bf02255899  0.546
1999 Huh JR, Park JM, Kim M, Carlson BA, Hatfield DL, Lee BJ. Recruitment of TBP or TFIIB to a promoter proximal position leads to stimulation of RNA polymerase II transcription without activator proteins both in vivo and in vitro. Biochemical and Biophysical Research Communications. 256: 45-51. PMID 10066420 DOI: 10.1006/Bbrc.1999.0280  0.303
1999 Carlson BA, Kwon SY, Chamorro M, Oroszlan S, Hatfield DL, Lee BJ. Transfer RNA modification status influences retroviral ribosomal frameshifting. Virology. 255: 2-8. PMID 10049815 DOI: 10.1006/Viro.1998.9569  0.568
1998 Moustafa ME, El-Saadani MA, Kandeel KM, Mansur DB, Lee BJ, Hatfield DL, Diamond AM. Overproduction of selenocysteine tRNA in Chinese hamster ovary cells following transfection of the mouse tRNA[Ser]Sec gene. Rna (New York, N.Y.). 4: 1436-43. PMID 9814763 DOI: 10.1017/S1355838298981043  0.377
1998 Gladyshev VN, Factor VM, Housseau F, Hatfield DL. Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells Biochemical and Biophysical Research Communications. 251: 488-493. PMID 9792801 DOI: 10.1006/Bbrc.1998.9495  0.522
1998 Chittum HS, Lane WS, Carlson BA, Roller PP, Lung FD, Lee BJ, Hatfield DL. Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps. Biochemistry. 37: 10866-70. PMID 9692979 DOI: 10.1021/Bi981042R  0.331
1998 Gladyshev VN, Jeang KT, Wootton JC, Hatfield DL. A new human selenium-containing protein. Purification, characterization, and cDNA sequence Journal of Biological Chemistry. 273: 8910-8915. PMID 9535873 DOI: 10.1074/Jbc.273.15.8910  0.561
1997 Park JM, Lee JY, Hatfield DL, Lee BJ. Differential mode of TBP utilization in transcription of the tRNA[Ser]Sec gene and TATA-less class III genes Gene. 196: 99-103. PMID 9322746 DOI: 10.1016/S0378-1119(97)00211-4  0.307
1997 Chittum HS, Baek HJ, Diamond AM, Fernandez-Salguero P, Gonzalez F, Ohama T, Hatfield DL, Kuehn M, Lee BJ. Selenocysteine tRNA[Ser]Sec levels and selenium-dependent glutathione peroxidase activity in mouse embryonic stem cells heterozygous for a targeted mutation in the tRNA[Ser]Sec gene. Biochemistry. 36: 8634-9. PMID 9214310 DOI: 10.1021/Bi970608T  0.357
1996 Park JM, Yang ES, Hatfield DL, Lee BJ. Analysis of the selenocysteine tRNA[Ser]Sec gene transcription in vitro using Xenopus oocyte extracts. Biochemical and Biophysical Research Communications. 226: 231-236. PMID 8806619 DOI: 10.1006/Bbrc.1996.1338  0.343
1995 Park JM, Choi IS, Kang SG, Lee JY, Hatfield DL, Lee BJ. Upstream promoter elements are sufficient for selenocysteine tRNA[Ser]Sec gene transcription and to determine the transcription start point. Gene. 162: 13-19. PMID 7557401 DOI: 10.1016/0378-1119(95)00340-C  0.35
1994 Choi IS, Diamond AM, Crain PF, Kolker JD, McCloskey JA, Hatfield DL. Reconstitution of the biosynthetic pathway of selenocysteine tRNAs in Xenopus oocytes. Biochemistry. 33: 601-5. PMID 8286391 DOI: 10.1021/Bi00168A027  0.378
1992 Hatfield DL, Levin JG, Rein A, Oroszlan S. Translational suppression in retroviral gene expression. Advances in Virus Research. 41: 193-239. PMID 1575083 DOI: 10.1016/S0065-3527(08)60037-8  0.323
1992 Diamond AM, Cruz R, Bencsics C, Hatfield D. A pseudogene for human glutathione peroxidase. Gene. 122: 377-80. PMID 1487153 DOI: 10.1016/0378-1119(92)90230-M  0.31
1991 Hatfield D, Lee BJ, Hampton L, Diamond AM. Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells. Nucleic Acids Research. 19: 939-43. PMID 2017375 DOI: 10.1093/Nar/19.4.939  0.375
1990 Hatfield D, Oroszlan S. The where, what and how of ribosomal frameshifting in retroviral protein synthesis. Trends in Biochemical Sciences. 15: 186-190. PMID 2193436 DOI: 10.1016/0968-0004(90)90159-9  0.315
1988 Hatfield D, Thorgeirsson SS, Copeland TD, Oroszlan S, Bustin M. Immunopurification of the suppressor tRNA dependent rabbit. beta. -globin readthrough protein Biochemistry. 27: 1179-1183. PMID 3365379 DOI: 10.1021/Bi00404A017  0.313
1987 Lee BJ, de la Peña P, Tobian JA, Zasloff M, Hatfield D. Unique pathway of expression of an opal suppressor phosphoserine tRNA. Proceedings of the National Academy of Sciences of the United States of America. 84: 6384-8. PMID 3114749 DOI: 10.1073/Pnas.84.18.6384  0.406
1986 Smith DWE, Hatfield DL. Effects of post-transcriptional base modifications on the site-specific function of transfer RNA in eukaryote translation. Journal of Molecular Biology. 189: 663-671. PMID 3783686 DOI: 10.1016/0022-2836(86)90496-1  0.344
1985 Pratt K, Eden FC, You KH, O'Neill VA, Hatfield D. Conserved sequences in both coding and 5′ flanking regions of mammalian opal suppressor tRNA genes Nucleic Acids Research. 13: 4765-4775. PMID 4022772 DOI: 10.1093/Nar/13.13.4765  0.321
1985 Green MR, Hatfield DL, Miller MJ, Peacock AC. Prolactin homogeneously induces the tRNA population of mouse mammary explants. Biochemical and Biophysical Research Communications. 129: 233-9. PMID 4004876 DOI: 10.1016/0006-291X(85)91427-5  0.305
1985 Hatfield D. Suppression of termination codons in higher eukaryotes Trends in Biochemical Sciences. 10: 201-204. DOI: 10.1016/0968-0004(85)90192-6  0.359
1983 Hatfield DL, Dudock BS, Eden FC. Characterization and nucleotide sequence of a chicken gene encoding an opal suppressor tRNA and its flanking DNA segments. Proceedings of the National Academy of Sciences of the United States of America. 80: 4940-4. PMID 6308662 DOI: 10.1073/Pnas.80.16.4940  0.303
1982 Hatfield D, Diamond A, Dudock B. Opal suppressor serine tRNAs from bovine liver form phosphoseryl-tRNA. Proceedings of the National Academy of Sciences of the United States of America. 79: 6215-9. PMID 6815648 DOI: 10.1073/Pnas.79.20.6215  0.353
1981 Diamond A, Dudock B, Hatfield D. Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon. Cell. 25: 497-506. PMID 6912798 DOI: 10.1016/0092-8674(81)90068-4  0.334
1981 Hatfield DL, Rice MJ, Mushinski JF. Comparison of the codon recognition properties and of the utilization of normal and tumor specific Phe-tRNAs in protein synthesis Cancer Letters. 12: 251-258. PMID 6911052 DOI: 10.1016/0304-3835(81)90076-8  0.33
1980 Hatfield D, Richer L, Lyon J, Rice M. Relative utilization of mammalian Lys‐tRNA isoacceptors in protein synthesis Febs Letters. 113: 249-252. PMID 6771159 DOI: 10.1016/0014-5793(80)80603-X  0.318
1979 Hatfield D, Matthews CR, Rice M. Aminoacyl-transfer RNA populations in mammalian cells. Chromatographic profiles and patterns of codon recognition Bba Section Nucleic Acids and Protein Synthesis. 564: 414-423. PMID 259017 DOI: 10.1016/0005-2787(79)90032-7  0.304
1974 Hofnung M, Hatfield D, Schwartz M. malB Region in Escherichia Coli K-12: Characterization of New Mutations Journal of Bacteriology. 117: 40-47. PMID 4587612 DOI: 10.1128/Jb.117.1.40-47.1974  0.304
1972 Hatfield D. Recognition of nonsense codons in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 69: 3014-3018. PMID 4562751 DOI: 10.1073/Pnas.69.10.3014  0.31
1971 Hofnung M, Schwartz M, Hatfield D. Complementation studies in the maltose-A region of the Escherichia coli K12 genetic map. Journal of Molecular Biology. 61: 681-694. PMID 4943758 DOI: 10.1016/0022-2836(71)90072-6  0.308
1971 Hatfield D, Nirenberg M. Binding of radioactive oligonucleotides to ribosomes. Biochemistry. 10: 4318-23. PMID 4942456 DOI: 10.1021/Bi00799A025  0.487
1966 Nirenberg M, Caskey T, Marshall R, Brimacombe R, Kellogg D, Doctor B, Hatfield D, Levin J, Rottman F, Pestka S, Wilcox M, Anderson F. The RNA code and protein synthesis. Cold Spring Harbor Symposia On Quantitative Biology. 31: 11-24. PMID 5237186 DOI: 10.1101/Sqb.1966.031.01.008  0.621
1964 HATFIELD D, WYNGAARDEN JB. 3-RIBOSYLPURINES. II. STUDIES ON (3-RIBOSYLXANTHINE) 5'-PHOSPHATE AND ON RIBONUCLEOTIDE DERIVATIVES OF CERTAIN URACIL ANALOGUES. The Journal of Biological Chemistry. 239: 2587-92. PMID 14235539  0.504
1964 HATFIELD D, WYNGAARDEN JB. 3-RIBOSYLPURINES. I. SYNTHESIS OF (3-RIBOSYLURIC ACID) 5'-PHOSPHATE AND (3-RIBOSYLXANTHINE) 5'-PHOSPHATE BY A PYRIMIDINE RIBONUCLEOTIDE PYROPHOSPHORYLASE OF BEEF ERYTHROCYTES. The Journal of Biological Chemistry. 239: 2580-6. PMID 14235538  0.531
1964 HATFIELD D, GREENLAND RA, STEWART HL, WYNGAARDEN JB. BIOSYNTHESIS OF A NEW URIC ACID RIBONUCLEOTIDE. Biochimica Et Biophysica Acta. 91: 163-6. PMID 14227265  0.518
1963 HATFIELD D, FORREST HS, WYNGAARDEN JB. Biosynthesis of a new xanthine ribonucleotide by beef erythrocytes. Biochimica Et Biophysica Acta. 68: 322-4. PMID 13960942  0.674
1962 HATFIELD D, FORREST HS. Biosynthesis of 3-ribosyluric acid (uric acid riboside). Biochimica Et Biophysica Acta. 62: 185-7. PMID 14036088 DOI: 10.1016/0006-3002(62)90512-7  0.543
1961 Hatfield DL, Van Baalen C, Forrest HS. Pteridines in blue green algae. Plant Physiology. 36: 240-3. PMID 16655500 DOI: 10.1104/Pp.36.2.240  0.532
1959 FORREST HS, HATFIELD D, VAN BAALEN C. Characterization of a second yellow compound from Drosophila melanogaster. Nature. 183: 1269-70. PMID 13657082 DOI: 10.1038/1831269A0  0.554
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