Year |
Citation |
Score |
2024 |
Samukha V, Fantasma F, D'Urso G, Caprari C, De Felice V, Saviano G, Lauro G, Casapullo A, Chini MG, Bifulco G, Iorizzi M. NMR Metabolomics and Chemometrics of Commercial Varieties of L. Seeds from Italy and In Vitro Antioxidant and Antifungal Activity. Plants (Basel, Switzerland). 13. PMID 38256780 DOI: 10.3390/plants13020227 |
0.734 |
|
2024 |
Capuano A, D'Urso G, Aliberti M, Ruggiero D, Terracciano S, Festa C, Tosco A, Chini MG, Lauro G, Bifulco G, Casapullo A. Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A. Marine Drugs. 22. PMID 38248666 DOI: 10.3390/md22010041 |
0.765 |
|
2024 |
Ciaglia T, Vestuto V, Di Sarno V, Musella S, Smaldone G, Di Matteo F, Napolitano V, Miranda MR, Pepe G, Basilicata MG, Novi S, Capolupo I, Bifulco G, Campiglia P, Gomez-Monterrey I, et al. Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization. European Journal of Medicinal Chemistry. 266: 116128. PMID 38232463 DOI: 10.1016/j.ejmech.2024.116128 |
0.699 |
|
2023 |
De Vita S, Meninno S, Capasso L, Colarusso E, Chini MG, Lauro G, Rinaldi R, De Cicco A, Sian V, Terracciano S, Nebbioso A, Lattanzi A, Bifulco G. 2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines. Bioorganic & Medicinal Chemistry. 93: 117444. PMID 37611334 DOI: 10.1016/j.bmc.2023.117444 |
0.831 |
|
2023 |
Parisi V, Donadio G, Bellone ML, Belaabed S, Bader A, Bisio A, Iobbi V, Gazzillo E, Chini MG, Bifulco G, Faraone I, Vassallo A. Exploring the Anticancer Potential of (Hochst.) Leaf Surface Extract: Discovering New Diterpenes as Heat Shock Protein 70 (Hsp70) Binding Agents. Plants (Basel, Switzerland). 12. PMID 37446982 DOI: 10.3390/plants12132421 |
0.667 |
|
2023 |
Gazzillo E, Pierri M, Colarusso E, Chini MG, Ferraro MG, Piccolo M, Irace C, Bruno I, Bifulco G, Terracciano S, Lauro G. Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9. Bioorganic Chemistry. 139: 106677. PMID 37352721 DOI: 10.1016/j.bioorg.2023.106677 |
0.842 |
|
2023 |
Musella S, D'Avino D, Peltner LK, Di Sarno V, Cerqua I, Merciai F, Vestuto V, Ciaglia T, Smaldone G, Di Matteo F, Di Micco S, Napolitano V, Bifulco G, Pepe G, Sommella EM, et al. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis. Journal of Medicinal Chemistry. PMID 37334504 DOI: 10.1021/acs.jmedchem.3c00831 |
0.32 |
|
2023 |
Rogati F, Maioli C, Lauro G, Caprioglio D, Imperio D, Del Grosso E, Botta B, Mannina L, Bifulco G, Ingallina C, Minassi A. A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids. Journal of Natural Products. PMID 37036806 DOI: 10.1021/acs.jnatprod.3c00067 |
0.652 |
|
2023 |
De Vita S, Chini MG, Bifulco G, Lauro G. Target identification by structure-based computational approaches: Recent advances and perspectives. Bioorganic & Medicinal Chemistry Letters. 83: 129171. PMID 36739998 DOI: 10.1016/j.bmcl.2023.129171 |
0.757 |
|
2022 |
Potenza M, Giordano A, Chini MG, Saviano A, Kretzer C, Raucci F, Russo M, Lauro G, Terracciano S, Bruno I, Iorizzi M, Hofstetter RK, Pace S, Maione F, Werz O, ... Bifulco G, et al. Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E and Leukotriene Biosynthesis Inhibitors. Acs Medicinal Chemistry Letters. 14: 26-34. PMID 36655121 DOI: 10.1021/acsmedchemlett.2c00343 |
0.814 |
|
2022 |
Colarusso E, Ceccacci S, Monti MC, Gazzillo E, Giordano A, Chini MG, Ferraro MG, Piccolo M, Ruggiero D, Irace C, Terracciano S, Bruno I, Bifulco G, Lauro G. Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders. European Journal of Medicinal Chemistry. 247: 115018. PMID 36577218 DOI: 10.1016/j.ejmech.2022.115018 |
0.833 |
|
2022 |
Cerqua I, Musella S, Peltner LK, D'Avino D, Di Sarno V, Granato E, Vestuto V, Di Matteo R, Pace S, Ciaglia T, Bilancia R, Smaldone G, Di Matteo F, Di Micco S, Bifulco G, et al. Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: and Anti-Inflammatory Characterization. Journal of Medicinal Chemistry. 65: 14456-14480. PMID 36318728 DOI: 10.1021/acs.jmedchem.2c00817 |
0.339 |
|
2022 |
Kılınc H, Masullo M, Lauro G, D'Urso G, Alankus O, Bifulco G, Piacente S. Scabiosa atropurpurea: A rich source of iridoids with α-glucosidase inhibitory activity evaluated by in vitro and in silico studies. Phytochemistry. 205: 113471. PMID 36241054 DOI: 10.1016/j.phytochem.2022.113471 |
0.672 |
|
2022 |
Di Micco S, Terracciano S, Pierri M, Cantone V, Liening S, König S, Garscha U, Hofstetter RK, Koeberle A, Werz O, Bruno I, Bifulco G. Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors. Chemmedchem. PMID 36111583 DOI: 10.1002/cmdc.202200327 |
0.808 |
|
2022 |
Micco SD, Lauro G, Bifulco G. Extensive molecular dynamics simulations disclosed the stability of mPGES-1 enzyme and the structural role of glutathione (GSH) cofactor. Molecular Informatics. PMID 36075865 DOI: 10.1002/minf.202200140 |
0.785 |
|
2022 |
De Vita S, Finamore C, Chini MG, Saviano G, De Felice V, De Marino S, Lauro G, Casapullo A, Fantasma F, Trombetta F, Bifulco G, Iorizzi M. Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches. Plants (Basel, Switzerland). 11. PMID 35807623 DOI: 10.3390/plants11131671 |
0.783 |
|
2022 |
Donadio G, Chini MG, Parisi V, Mensitieri F, Malafronte N, Bifulco G, Bisio A, De Tommasi N, Bader A. Diterpenoid Constituents of and Evaluation of Their Antimicrobial Activity. Journal of Natural Products. PMID 35748331 DOI: 10.1021/acs.jnatprod.1c01093 |
0.654 |
|
2022 |
Gazzillo E, Terracciano S, Ruggiero D, Potenza M, Chini MG, Lauro G, Fischer K, Hofstetter RK, Giordano A, Werz O, Bruno I, Bifulco G. Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation. Molecules (Basel, Switzerland). 27. PMID 35744994 DOI: 10.3390/molecules27123866 |
0.817 |
|
2022 |
Di Sarno V, Giovannelli P, Medina-Peris A, Ciaglia T, Di Donato M, Musella S, Lauro G, Vestuto V, Smaldone G, Di Matteo F, Bifulco G, Castoria G, Migliaccio A, Fernandez-Carvajal A, Campiglia P, et al. New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models. European Journal of Medicinal Chemistry. 238: 114435. PMID 35598411 DOI: 10.1016/j.ejmech.2022.114435 |
0.665 |
|
2022 |
Baradaran Rahimi V, Momeni-Moghaddam MA, Chini MG, Saviano A, Maione F, Bifulco G, Rahmanian-Devin P, Jebalbarezy A, Askari VR. Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-B: A Mechanistic and Study. Evidence-Based Complementary and Alternative Medicine : Ecam. 2022: 7969422. PMID 35571740 DOI: 10.1155/2022/7969422 |
0.563 |
|
2022 |
Masullo M, Lauro G, Cerulli A, Bifulco G, Piacente S. : A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by and Studies. Frontiers in Plant Science. 13: 805660. PMID 35237285 DOI: 10.3389/fpls.2022.805660 |
0.656 |
|
2022 |
Boudermine S, Parisi V, Lemoui R, Boudiar T, Chini MG, Franceschelli S, Pecoraro M, Pascale M, Bifulco G, Braca A, De Tommasi N, De Leo M. Cytotoxic Sesquiterpenoids from Aerial Parts. Journal of Natural Products. PMID 35196017 DOI: 10.1021/acs.jnatprod.1c01211 |
0.641 |
|
2022 |
Ruggiero D, Terracciano S, Lauro G, Pecoraro M, Franceschelli S, Bifulco G, Bruno I. Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein. Molecules (Basel, Switzerland). 27. PMID 35163936 DOI: 10.3390/molecules27030665 |
0.82 |
|
2022 |
Saviano A, De Vita S, Chini MG, Marigliano N, Lauro G, Casillo GM, Raucci F, Iorizzi M, Hofstetter RK, Fischer K, Koeberle A, Werz O, Maione F, Bifulco G. In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway. Biomolecules. 12. PMID 35053247 DOI: 10.3390/biom12010099 |
0.754 |
|
2022 |
Pierri M, Gazzillo E, Chini MG, Ferraro MG, Piccolo M, Maione F, Irace C, Bifulco G, Bruno I, Terracciano S, Lauro G. Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders. Bioorganic Chemistry. 118: 105480. PMID 34823196 DOI: 10.1016/j.bioorg.2021.105480 |
0.828 |
|
2021 |
De Vita S, Chini MG, Bifulco G, Lauro G. Insights into the Ligand Binding to Bromodomain-Containing Protein 9 (BRD9): A Guide to the Selection of Potential Binders by Computational Methods. Molecules (Basel, Switzerland). 26. PMID 34885774 DOI: 10.3390/molecules26237192 |
0.752 |
|
2021 |
De Vita S, Chini MG, Saviano G, Finamore C, Festa C, Lauro G, De Marino S, Russo R, Avagliano C, Casapullo A, Calignano A, Bifulco G, Iorizzi M. Biological Profile of Two L. Metabolites Using Computational Approaches and In Vitro Tests. Biomolecules. 11. PMID 34680124 DOI: 10.3390/biom11101490 |
0.792 |
|
2021 |
Di Sarno V, Lauro G, Musella S, Ciaglia T, Vestuto V, Sala M, Scala MC, Smaldone G, Di Matteo F, Novi S, Tecce MF, Moltedo O, Bifulco G, Campiglia P, Gomez-Monterrey IM, et al. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. European Journal of Medicinal Chemistry. 226: 113863. PMID 34571172 DOI: 10.1016/j.ejmech.2021.113863 |
0.698 |
|
2021 |
Potenza M, Sciarretta M, Chini MG, Saviano A, Maione F, D'Auria MV, De Marino S, Giordano A, Hofstetter RK, Festa C, Werz O, Bifulco G. Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways. European Journal of Medicinal Chemistry. 224: 113693. PMID 34315041 DOI: 10.1016/j.ejmech.2021.113693 |
0.832 |
|
2021 |
Di Micco S, Terracciano S, Ruggiero D, Potenza M, Vaccaro MC, Fischer K, Werz O, Bruno I, Bifulco G. Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition. Frontiers in Chemistry. 9: 676631. PMID 34046398 DOI: 10.3389/fchem.2021.676631 |
0.823 |
|
2021 |
Potenza M, Cavalluzzi MM, Milani G, Lauro G, Carino A, Roselli R, Fiorucci S, Zampella A, Pierri CL, Lentini G, Bifulco G. Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR). Bioorganic Chemistry. 111: 104897. PMID 33901797 DOI: 10.1016/j.bioorg.2021.104897 |
0.813 |
|
2021 |
Bellone ML, Muñoz Camero C, Chini MG, Dal Piaz F, Hernandez V, Bifulco G, De Tommasi N, Braca A. Limonoids from and : Heat Shock Protein 90 (Hsp90) Modulator Properties of Chisomicine D. Journal of Natural Products. PMID 33661631 DOI: 10.1021/acs.jnatprod.0c01217 |
0.607 |
|
2021 |
Masullo M, Lauro G, Cerulli A, Kontek B, Olas B, Bifulco G, Piacente S, Pizza C. Giffonins, Antioxidant Diarylheptanoids from , and Their Ability to Prevent Oxidative Changes in Human Plasma Proteins. Journal of Natural Products. PMID 33616390 DOI: 10.1021/acs.jnatprod.0c01251 |
0.628 |
|
2021 |
Zadali R, Nejad-Ebrahimi S, Hadjiakhoondi A, Fiengo L, D'Ambola M, De Vita S, Tofighi Z, Chini MG, Bifulco G, De Tommasi N. Diterpenoids from Zhumeria majdae roots as potential heat shock protein 90 (HSP90) modulators. Phytochemistry. 185: 112685. PMID 33607577 DOI: 10.1016/j.phytochem.2021.112685 |
0.658 |
|
2020 |
De Vita S, Chini MG, Lauro G, Bifulco G. Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19). Rsc Advances. 10: 40867-40875. PMID 35519188 DOI: 10.1039/d0ra09010g |
0.777 |
|
2020 |
Farooq S, Qayum A, Nalli Y, Lauro G, Chini MG, Bifulco G, Chaubey A, Singh SK, Riyaz-Ul-Hassan S, Ali A. Discovery of a Secalonic Acid Derivative from , an Endophyte of Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells. Acs Omega. 5: 24296-24310. PMID 33015446 DOI: 10.1021/acsomega.0c02505 |
0.752 |
|
2020 |
Bertamino A, Ostacolo C, Medina A, Di Sarno V, Lauro G, Ciaglia T, Vestuto V, Pepe G, Basilicata MG, Musella S, Smaldone G, Cristiano C, Gonzalez-Rodriguez S, Fernandez-Carvajal A, Bifulco G, et al. Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities. Journal of Medicinal Chemistry. PMID 32787109 DOI: 10.1021/Acs.Jmedchem.0C00816 |
0.681 |
|
2020 |
Nemati F, Salehi P, Bararjanian M, Hadian N, Mohebbi M, Lauro G, Ruggiero D, Terracciano S, Bifulco G, Bruno I. Discovery of noscapine derivatives as potential β-tubulin inhibitors. Bioorganic & Medicinal Chemistry Letters. 30: 127489. PMID 32784088 DOI: 10.1016/J.Bmcl.2020.127489 |
0.826 |
|
2020 |
Chini MG, Giordano A, Potenza M, Terracciano S, Fischer K, Vaccaro MC, Colarusso E, Bruno I, Riccio R, Koeberle A, Werz O, Bifulco G. Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE Levels. Acs Medicinal Chemistry Letters. 11: 783-789. PMID 32435385 DOI: 10.1021/Acsmedchemlett.9B00618 |
0.79 |
|
2020 |
Lauro G, Terracciano S, Cantone V, Ruggiero D, Fischer K, Pace S, Werz O, Bruno I, Bifulco G. A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors. Chemmedchem. PMID 32022480 DOI: 10.1002/Cmdc.201900694 |
0.833 |
|
2020 |
Lauro G, Das P, Riccio R, Reddy DS, Bifulco G. DFT/NMR approach for the configuration assignment of groups of stereoisomers by the combination and comparison of experimental and predicted sets of data. The Journal of Organic Chemistry. PMID 31961156 DOI: 10.1021/Acs.Joc.9B03129 |
0.723 |
|
2020 |
Lauro G, Bifulco G. Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches European Journal of Organic Chemistry. 2020: 3929-3941. DOI: 10.1002/Ejoc.201901878 |
0.314 |
|
2019 |
Chini MG, Urbani D, Dambruoso P, Riccio R, Bifulco G. Elucidating heteroatom influence on homonuclear J coupling constants by DFT/NMR approach. Magnetic Resonance in Chemistry : Mrc. PMID 31883165 DOI: 10.1002/Mrc.4983 |
0.695 |
|
2019 |
Di Micco S, Masullo M, Bandak AF, Berger JM, Riccio R, Piacente S, Bifulco G. Garcinol and Related Polyisoprenylated Benzophenones as Topoisomerase II Inhibitors: Biochemical and Molecular Modeling Studies. Journal of Natural Products. 82: 2768-2779. PMID 31618025 DOI: 10.1021/Acs.Jnatprod.9B00382 |
0.581 |
|
2019 |
De Vita S, Lauro G, Ruggiero D, Terracciano S, Riccio R, Bifulco G. Protein Preparation Automatic Protocol for High-Throughput Inverse Virtual Screening: Accelerating the Target Identification by Computational Methods. Journal of Chemical Information and Modeling. PMID 31593460 DOI: 10.1021/Acs.Jcim.9B00428 |
0.819 |
|
2019 |
Nalli Y, Jan S, Lauro G, Ur Rasool J, Lone WI, Sarkar AR, Banday J, Bifulco G, Laatsch H, Syed SH, Ali A. Isolation, Synthesis And Structure Determination Of Cannabidiol Derivatives And Their Cytotoxic Activities. Natural Product Research. 1-10. PMID 31282748 DOI: 10.1080/14786419.2019.1638381 |
0.729 |
|
2019 |
Maione F, Minosi P, Di Giannuario A, Raucci F, Chini MG, De Vita S, Bifulco G, Mascolo N, Pieretti S. Long-Lasting Anti-Inflammatory and Antinociceptive Effects of Acute Ammonium Glycyrrhizinate Administration: Pharmacological, Biochemical, and Docking Studies. Molecules (Basel, Switzerland). 24. PMID 31277398 DOI: 10.3390/Molecules24132453 |
0.606 |
|
2019 |
Benteldjoune M, Chini MG, Iannuzzi AM, Kabouche A, Kabouche Z, DʼAmbola M, Marzocco S, Autore G, Bifulco G, De Tommasi N. Guaianolides from Ormenis mixta: Structural Insights and Evaluation of Their Anti-inflammatory Profile. Planta Medica. PMID 31163459 DOI: 10.1055/A-0941-0364 |
0.666 |
|
2019 |
Sun P, Cai FY, Lauro G, Tang H, Su L, Wang HL, Li HH, Mándi A, Kurtán T, Riccio R, Bifulco G, Zhang W. Immunomodulatory Biscembranoids and Assignment of Their Relative and Absolute Configurations: Data Set Modulation in the Density Functional Theory/Nuclear Magnetic Resonance Approach. Journal of Natural Products. PMID 30957492 DOI: 10.1021/Acs.Jnatprod.8B01037 |
0.729 |
|
2019 |
D'Ambola M, Fiengo L, Chini MG, Cotugno R, Bader A, Bifulco G, Braca A, De Tommasi N, Dal Piaz F. Fusicoccane Diterpenes from Hypoestes forsskaolii as Heat Shock Protein 90 (Hsp90) Modulators. Journal of Natural Products. PMID 30839211 DOI: 10.1021/Acs.Jnatprod.8B00924 |
0.695 |
|
2019 |
Gerstmeier J, Kretzer C, Di Micco S, Miek L, Butschek H, Cantone V, Bilancia R, Rizza R, Troisi F, Cardullo N, Tringali C, Ialenti A, Rossi A, Bifulco G, Werz O, et al. Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: a promising pharmacological strategy for anti-inflammatory therapy. Biochemical Pharmacology. PMID 30836057 DOI: 10.1016/J.Bcp.2019.03.003 |
0.366 |
|
2019 |
Ostacolo C, Di Sarno V, Lauro G, Pepe G, Musella S, Ciaglia T, Vestuto V, Autore G, Bifulco G, Marzocco S, Campiglia P, Gomez-Monterrey IM, Bertamino A. Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach. European Journal of Medicinal Chemistry. 167: 61-75. PMID 30763817 DOI: 10.1016/J.Ejmech.2019.01.066 |
0.713 |
|
2019 |
Terracciano S, Chini MG, Vaccaro MC, Strocchia M, Foglia A, Vassallo A, Saturnino C, Riccio R, Bifulco G, Bruno I. Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors. Chemical Communications (Cambridge, England). 52: 13515. PMID 27805204 DOI: 10.1039/C6Cc90506D |
0.789 |
|
2018 |
Lauro G, Cantone V, Potenza M, Fischer K, Koeberle A, Werz O, Riccio R, Bifulco G. Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol. Medchemcomm. 9: 2028-2036. PMID 30746063 DOI: 10.1039/C8Md00497H |
0.826 |
|
2018 |
Jachak GR, Athawale PR, Agarwal H, Barthwal MK, Lauro G, Bifulco G, Reddy DS. Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation. Organic & Biomolecular Chemistry. PMID 30478463 DOI: 10.1039/C8Ob02713G |
0.69 |
|
2018 |
Di Micco S, Giannini C, Previtali A, Lucenti E, Bifulco G. Chemical shift assignment of mono- and di-bromo triimidazo[1,2-a:1',2'-c:1",2"-e][1,3,5] triazine derivatives by DFT/NMR integrated approach. Magnetic Resonance in Chemistry : Mrc. PMID 30421826 DOI: 10.1002/Mrc.4804 |
0.368 |
|
2018 |
Khalfaoui A, Chini MG, Bouheroum M, Belaabed S, Lauro G, Terracciano S, Vaccaro MC, Bruno I, Benayache S, Mancini I, Bifulco G. Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells. Journal of Natural Products. PMID 30063349 DOI: 10.1021/Acs.Jnatprod.8B00234 |
0.815 |
|
2018 |
Di Micco S, Pulvirenti L, Bruno I, Terracciano S, Russo A, Vaccaro MC, Ruggiero D, Muccilli V, Cardullo N, Tringali C, Riccio R, Bifulco G. Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors. Bioorganic & Medicinal Chemistry. PMID 29934219 DOI: 10.1016/J.Bmc.2018.06.019 |
0.826 |
|
2018 |
Terracciano S, Lauro G, Russo A, Vaccaro MC, Vassallo A, De Marco M, Ranieri B, Rosati A, Turco MC, Riccio R, Bifulco G, Bruno I. Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics. Chemical Communications (Cambridge, England). PMID 29926854 DOI: 10.1039/C8Cc03399D |
0.791 |
|
2018 |
Giordano A, Forte G, Massimo L, Riccio R, Bifulco G, Di Micco S. Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening. European Journal of Medicinal Chemistry. 152: 253-263. PMID 29730188 DOI: 10.1016/J.Ejmech.2018.04.018 |
0.642 |
|
2018 |
Terracciano S, Russo A, Chini MG, Vaccaro MC, Potenza M, Vassallo A, Riccio R, Bifulco G, Bruno I. Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain. Scientific Reports. 8: 1709. PMID 29374167 DOI: 10.1038/S41598-017-14902-Y |
0.795 |
|
2018 |
Terracciano S, Chini MG, Vaccaro MC, Strocchia M, Foglia A, Vassallo A, Saturnino C, Riccio R, Bifulco G, Bruno I. Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors. Chemical Communications (Cambridge, England). 52: 12857-12860. PMID 27731433 DOI: 10.1039/c6cc06379a |
0.739 |
|
2017 |
Maione F, Piccolo M, De Vita S, Chini MG, Cristiano C, De Caro C, Lippiello P, Miniaci MC, Santamaria R, Irace C, De Feo V, Calignano A, Mascolo N, Bifulco G. Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease. Pharmacological Research. PMID 29158049 DOI: 10.1016/J.Phrs.2017.11.018 |
0.614 |
|
2017 |
Di Micco S, Terracciano S, Cantone V, Fischer K, Koeberle A, Foglia A, Riccio R, Werz O, Bruno I, Bifulco G. Discovery of new potent molecular entities able to inhibit mPGES-1. European Journal of Medicinal Chemistry. PMID 29133047 DOI: 10.1016/J.Ejmech.2017.10.039 |
0.824 |
|
2017 |
Bertamino A, Lauro G, Ostacolo C, Di Sarno V, Musella S, Ciaglia T, Campiglia P, Bifulco G, Gomez-Monterrey IM. Ring-Fused Cyclic Aminals from Tetrahydro-β-carboline-Based Dipeptide Compounds. The Journal of Organic Chemistry. 82: 12014-12027. PMID 29091729 DOI: 10.1021/Acs.Joc.7B01656 |
0.66 |
|
2017 |
Proto MC, Fiore D, Piscopo C, Franceschelli S, Bizzarro V, Laezza C, Lauro G, Feoli A, Tosco A, Bifulco G, Sbardella G, Bifulco M, Gazzerro P. Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer. Scientific Reports. 7: 11678. PMID 28916833 DOI: 10.1038/S41598-017-11688-X |
0.63 |
|
2017 |
Liu HB, Lauro G, O'Connor RD, Lohith K, Kelly M, Colin P, Bifulco G, Bewley CA. Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge. Journal of Natural Products. PMID 28837335 DOI: 10.1021/Acs.Jnatprod.7B00452 |
0.687 |
|
2017 |
Cerulli A, Lauro G, Masullo M, Cantone V, Olas B, Kontek B, Nazzaro F, Bifulco G, Piacente S. Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities. Journal of Natural Products. 80: 1703-1713. PMID 28520428 DOI: 10.1021/Acs.Jnatprod.6B00703 |
0.687 |
|
2017 |
Dardic D, Lauro G, Bifulco G, Laboudie P, Sakhaii P, Bauer A, Vilcinskas A, Hammann PE, Plaza A. Svetamycins A-G, Unusual Piperazic Acid-Containing Peptides from Streptomyces sp. The Journal of Organic Chemistry. PMID 28489377 DOI: 10.1021/Acs.Joc.7B00228 |
0.661 |
|
2017 |
Li J, Li C, Riccio R, Lauro G, Bifulco G, Li TJ, Tang H, Zhuang CL, Ma H, Sun P, Zhang W. Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp. Marine Drugs. 15. PMID 28467388 DOI: 10.3390/Md15050129 |
0.771 |
|
2016 |
Sun P, Yu Q, Li J, Riccio R, Lauro G, Bifulco G, Kurtán T, Mándi A, Tang H, Li TJ, Zhuang CL, Gerwick WH, Zhang W. Bissubvilides A and B, Cembrane-Capnosane Heterodimers from the Soft Coral Sarcophyton subviride. Journal of Natural Products. PMID 27704808 DOI: 10.1021/Acs.Jnatprod.6B00453 |
0.733 |
|
2016 |
Lauro G, Manfra M, Pedatella S, Fischer K, Cantone V, Terracciano S, Bertamino A, Ostacolo C, Gomez-Monterrey I, De Nisco M, Riccio R, Novellino E, Werz O, Campiglia P, Bifulco G. Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening. European Journal of Medicinal Chemistry. 125: 278-287. PMID 27688183 DOI: 10.1016/J.Ejmech.2016.09.042 |
0.822 |
|
2016 |
Abbas Bukhari SN, Lauro G, Jantan I, Chee CF, Amjad MW, Bifulco G, Sher H, Abdullah I, Rahman NA. Anti-inflammatory trends of new benzimidazole derivatives. Future Medicinal Chemistry. PMID 27654499 DOI: 10.4155/Fmc-2016-0062 |
0.656 |
|
2016 |
Chini MG, Malafronte N, Vaccaro MC, Gualtieri MJ, Vassallo A, Vasaturo M, Castellano S, Milite C, Leone A, Bifulco G, De Tommasi N, Dal Piaz F. Identification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27492719 DOI: 10.1002/Chem.201602242 |
0.702 |
|
2016 |
Maione F, Cantone V, Pace S, Chini MG, Bisio A, Romussi G, Pieretti S, Werz O, Koeberle A, Mascolo N, Bifulco G. Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions. British Journal of Pharmacology. PMID 27464306 DOI: 10.1111/Bph.13545 |
0.617 |
|
2016 |
Lauro G, Tortorella P, Bertamino A, Ostacolo C, Koeberle A, Fischer K, Bruno I, Terracciano S, Gomez-Monterrey IM, Tauro M, Loiodice F, Novellino E, Riccio R, Werz O, Campiglia P, ... Bifulco G, et al. Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme. Chemmedchem. PMID 26915684 DOI: 10.1002/Cmdc.201500598 |
0.831 |
|
2016 |
Di Micco S, Spatafora C, Cardullo N, Riccio R, Fischer K, Pergola C, Koeberle A, Werz O, Chalal M, Vervandier-Fasseur D, Tringali C, Bifulco G. 2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of mPGES-1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 26777299 DOI: 10.1016/J.Bmc.2016.01.002 |
0.665 |
|
2016 |
Terracciano S, Foglia A, Chini MG, Vaccaro MC, Russo A, Dal Piaz F, Saturnino C, Riccio R, Bifulco G, Bruno I. New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors Rsc Advances. 6: 82330-82340. DOI: 10.1039/C6Ra17235K |
0.813 |
|
2015 |
Masullo M, Cantone V, Cerulli A, Lauro G, Messano F, Russo GL, Pizza C, Bifulco G, Piacente S. Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni". Journal of Natural Products. PMID 26606246 DOI: 10.1021/Acs.Jnatprod.5B00695 |
0.679 |
|
2015 |
Iranshahi M, Chini MG, Masullo M, Sahebkar A, Javidnia A, Chitsazian Yazdi M, Pergola C, Koeberle A, Werz O, Pizza C, Terracciano S, Piacente S, Bifulco G. Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? The Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors. Journal of Natural Products. 78: 2867-79. PMID 26588603 DOI: 10.1021/Acs.Jnatprod.5B00700 |
0.807 |
|
2015 |
Dal Piaz F, Ferro P, Vassallo A, Vasaturo M, Forte G, Chini MG, Bifulco G, Tosco A, De Tommasi N. Identification and mechanism of action analysis of the new PARP-1 inhibitor 2″-hydroxygenkwanol A. Biochimica Et Biophysica Acta. 1850: 1806-14. PMID 25999161 DOI: 10.1016/J.Bbagen.2015.05.014 |
0.635 |
|
2015 |
Picaud S, Strocchia M, Terracciano S, Lauro G, Mendez J, Daniels DL, Riccio R, Bifulco G, Bruno I, Filippakopoulos P. 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain. Journal of Medicinal Chemistry. 58: 2718-36. PMID 25703523 DOI: 10.1021/Jm501893K |
0.824 |
|
2015 |
Terracciano S, Lauro G, Strocchia M, Fischer K, Werz O, Riccio R, Bruno I, Bifulco G. Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors. Acs Medicinal Chemistry Letters. 6: 187-91. PMID 25699159 DOI: 10.1021/Ml500433J |
0.815 |
|
2015 |
Renga B, Festa C, De Marino S, Di Micco S, D'Auria MVa, Bifulco G, Fiorucci S, Zampella A. Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists Steroids. 96: 121-131. PMID 25668616 DOI: 10.1016/J.Steroids.2015.01.024 |
0.325 |
|
2015 |
Strocchia M, Terracciano S, Chini MG, Vassallo A, Vaccaro MC, Dal Piaz F, Leone A, Riccio R, Bruno I, Bifulco G. Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold. Chemical Communications (Cambridge, England). 51: 3850-3. PMID 25656927 DOI: 10.1039/C4Cc10074C |
0.806 |
|
2015 |
Maione F, Cantone V, Chini MG, De Feo V, Mascolo N, Bifulco G. Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis. Fitoterapia. 100: 174-8. PMID 25497578 DOI: 10.1016/J.Fitote.2014.11.024 |
0.616 |
|
2015 |
Chini MG, Ferroni C, Cantone V, Dambruoso P, Varchi G, Pepe A, Fischer K, Pergola C, Werz O, Bruno I, Riccio R, Bifulco G. Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors Medchemcomm. 6: 75-79. DOI: 10.1039/C4Md00319E |
0.743 |
|
2015 |
Chini MG, Riccio R, Bifulco G. Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating? European Journal of Organic Chemistry. 2015: 1320-1324. DOI: 10.1002/Ejoc.201403569 |
0.555 |
|
2014 |
Scrima M, Lauro G, Grimaldi M, Di Marino S, Tosco A, Picardi P, Gazzerro P, Riccio R, Novellino E, Bifulco M, Bifulco G, D'Ursi AM. Structural evidence of N6-isopentenyladenosine as a new ligand of farnesyl pyrophosphate synthase. Journal of Medicinal Chemistry. 57: 7798-803. PMID 25184810 DOI: 10.1021/Jm500869X |
0.768 |
|
2014 |
Nadmid S, Plaza A, Lauro G, Garcia R, Bifulco G, Müller R. Hyalachelins A-C, unusual siderophores isolated from the terrestrial myxobacterium Hyalangium minutum. Organic Letters. 16: 4130-3. PMID 25058569 DOI: 10.1021/Ol501826A |
0.665 |
|
2014 |
Bukhari SN, Lauro G, Jantan I, Bifulco G, Amjad MW. Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A₂, cyclooxygenases, lipoxygenase and proinflammatory cytokines. Bioorganic & Medicinal Chemistry. 22: 4151-61. PMID 24938495 DOI: 10.1016/J.Bmc.2014.05.052 |
0.705 |
|
2014 |
Lauro G, Strocchia M, Terracciano S, Bruno I, Fischer K, Pergola C, Werz O, Riccio R, Bifulco G. Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E₂ synthase-1 enzyme (mPGES-1). European Journal of Medicinal Chemistry. 80: 407-15. PMID 24794772 DOI: 10.1016/J.Ejmech.2014.04.061 |
0.816 |
|
2014 |
Gong J, Sun P, Jiang N, Riccio R, Lauro G, Bifulco G, Li TJ, Gerwick WH, Zhang W. New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge Theonella swinhoei. Organic Letters. 16: 2224-7. PMID 24694058 DOI: 10.1021/Ol5007345 |
0.763 |
|
2014 |
Spatafora C, Barresi V, Bhusainahalli VM, Di Micco S, Musso N, Riccio R, Bifulco G, Condorelli D, Tringali C. Bio-inspired benzo[k,l]xanthene lignans: synthesis, DNA-interaction and antiproliferative properties. Organic & Biomolecular Chemistry. 12: 2686-701. PMID 24647864 DOI: 10.1039/C3Ob42521E |
0.594 |
|
2014 |
Masullo M, Menegazzi M, Di Micco S, Beffy P, Bifulco G, Dal Bosco M, Novelli M, Pizza C, Masiello P, Piacente S. Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways. Journal of Natural Products. 77: 543-9. PMID 24417609 DOI: 10.1021/Np400804Y |
0.321 |
|
2014 |
Di Micco S, Renga B, Carino A, D'Auria MV, Zampella A, Riccio R, Fiorucci S, Bifulco G. Structural insights into Estrogen Related Receptor-β modulation: 4-methylenesterols from Theonella swinhoei sponge as the first example of marine natural antagonists. Steroids. 80: 51-63. PMID 24315836 DOI: 10.1016/J.Steroids.2013.11.017 |
0.567 |
|
2013 |
Di Micco S, Zampella A, D'Auria MV, Festa C, De Marino S, Riccio R, Butts CP, Bifulco G. Plakilactones G and H from a marine sponge. Stereochemical determination of highly flexible systems by quantitative NMR-derived interproton distances combined with quantum mechanical calculations of (13)C chemical shifts. Beilstein Journal of Organic Chemistry. 9: 2940-9. PMID 24454574 DOI: 10.3762/Bjoc.9.331 |
0.547 |
|
2013 |
Festa C, D'Amore C, Renga B, Lauro G, De Marino S, D'Auria MV, Bifulco G, Zampella A, Fiorucci S. Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists Marine Drugs. 11: 2314-2327. PMID 23820629 DOI: 10.3390/Md11072314 |
0.719 |
|
2013 |
Terracciano S, Chini MG, Piaz FD, Vassallo A, Riccio R, Bruno I, Bifulco G. Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors. European Journal of Medicinal Chemistry. 65: 464-76. PMID 23770448 DOI: 10.1016/J.Ejmech.2013.05.016 |
0.831 |
|
2013 |
Di Micco S, Chini MG, Terracciano S, Bruno I, Riccio R, Bifulco G. Structural basis for the design and synthesis of selective HDAC inhibitors. Bioorganic & Medicinal Chemistry. 21: 3795-807. PMID 23693069 DOI: 10.1016/J.Bmc.2013.04.036 |
0.814 |
|
2013 |
Dal Piaz F, Cotugno R, Lepore L, Vassallo A, Malafronte N, Lauro G, Bifulco G, Belisario MA, De Tommasi N. Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells. Journal of Proteomics. 82: 14-26. PMID 23416714 DOI: 10.1016/J.Jprot.2013.01.030 |
0.687 |
|
2013 |
Dal Piaz F, Vassallo A, Temraz A, Cotugno R, Belisario MA, Bifulco G, Chini MG, Pisano C, De Tommasi N, Braca A. A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors. Journal of Medicinal Chemistry. 56: 1583-95. PMID 23362862 DOI: 10.1021/Jm301398Y |
0.682 |
|
2013 |
Bifulco G, Riccio R, Martin GE, Buevich AV, Williamson RT. Quantum chemical calculations of 1J(CC) coupling constants for the stereochemical determination of organic compounds. Organic Letters. 15: 654-7. PMID 23324108 DOI: 10.1021/Ol3034803 |
0.53 |
|
2013 |
Maldini M, Di Micco S, Montoro P, Darra E, Mariotto S, Bifulco G, Pizza C, Piacente S. Flavanocoumarins from Guazuma ulmifolia bark and evaluation of their affinity for STAT1. Phytochemistry. 86: 64-71. PMID 23158905 DOI: 10.1016/J.Phytochem.2012.10.011 |
0.431 |
|
2013 |
Pauwels E, Claeys D, Martins JC, Waroquier M, Bifulco G, Speybroeck VV, Madder A. Accurate prediction of <sup>1</sup>H chemical shifts in interstrand cross-linked DNA Rsc Advances. 3: 3925-3938. DOI: 10.1039/C3Ra22408B |
0.331 |
|
2012 |
Sepe V, Ummarino R, D'Auria MV, Taglialatela-Scafati O, Marino SD, D'Amore C, Renga B, Chini MG, Bifulco G, Nakao Y, Fusetani N, Fiorucci S, Zampella A. Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei. Marine Drugs. 10: 2448-66. PMID 23203270 DOI: 10.3390/Md10112448 |
0.641 |
|
2012 |
Margarucci L, Monti MC, Chini MG, Tosco A, Riccio R, Bifulco G, Casapullo A. The inactivation mechanism of human group IIA phospholipase A(2) by Scalaradial. Chembiochem : a European Journal of Chemical Biology. 13: 2259-64. PMID 23008213 DOI: 10.1002/Cbic.201200453 |
0.803 |
|
2012 |
Fiorucci S, Distrutti E, Bifulco G, D'Auria MV, Zampella A. Marine sponge steroids as nuclear receptor ligands. Trends in Pharmacological Sciences. 33: 591-601. PMID 23000093 DOI: 10.1016/J.Tips.2012.08.004 |
0.325 |
|
2012 |
Festa C, Lauro G, De Marino S, D'Auria MV, Monti MC, Casapullo A, D'Amore C, Renga B, Mencarelli A, Petek S, Bifulco G, Fiorucci S, Zampella A. Plakilactones from the marine sponge Plakinastrella mamillaris. discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ Journal of Medicinal Chemistry. 55: 8303-8317. PMID 22934537 DOI: 10.1021/Jm300911G |
0.779 |
|
2012 |
Dal Piaz F, Vassallo A, Chini MG, Cordero FM, Cardona F, Pisano C, Bifulco G, De Tommasi N, Brandi A. Natural iminosugar (+)-lentiginosine inhibits ATPase and chaperone activity of hsp90. Plos One. 7: e43316. PMID 22916240 DOI: 10.1371/Journal.Pone.0043316 |
0.676 |
|
2012 |
Sepe V, Ummarino R, D'Auria MV, Lauro G, Bifulco G, D'Amore C, Renga B, Fiorucci S, Zampella A. Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist. Organic & Biomolecular Chemistry. 10: 6350-62. PMID 22733410 DOI: 10.1039/C2Ob25800E |
0.675 |
|
2012 |
Chini MG, De Simone R, Bruno I, Riccio R, Dehm F, Weinigel C, Barz D, Werz O, Bifulco G. Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors. European Journal of Medicinal Chemistry. 54: 311-23. PMID 22683242 DOI: 10.1016/J.Ejmech.2012.05.014 |
0.824 |
|
2012 |
Plaza A, Garcia R, Bifulco G, Martinez JP, Hüttel S, Sasse F, Meyerhans A, Stadler M, Müller R. Aetheramides A and B, potent HIV-inhibitory depsipeptides from a myxobacterium of the new genus "Aetherobacter". Organic Letters. 14: 2854-7. PMID 22616796 DOI: 10.1021/Ol3011002 |
0.354 |
|
2012 |
Lauro G, Masullo M, Piacente S, Riccio R, Bifulco G. Inverse Virtual Screening allows the discovery of the biological activity of natural compounds. Bioorganic & Medicinal Chemistry. 20: 3596-602. PMID 22537682 DOI: 10.1016/J.Bmc.2012.03.072 |
0.776 |
|
2012 |
Renga B, Mencarelli A, D'Amore C, Cipriani S, D'Auria MV, Sepe V, Chini MG, Monti MC, Bifulco G, Zampella A, Fiorucci S. Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis. Plos One. 7: e30443. PMID 22291955 DOI: 10.1371/Journal.Pone.0030443 |
0.591 |
|
2012 |
De Marino S, Ummarino R, D'Auria MV, Chini MG, Bifulco G, D'Amore C, Renga B, Mencarelli A, Petek S, Fiorucci S, Zampella A. 4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity. Steroids. 77: 484-95. PMID 22285937 DOI: 10.1016/J.Steroids.2012.01.006 |
0.61 |
|
2012 |
Terracciano S, Chini MG, Riccio R, Bruno I, Bifulco G. Design, synthesis, and biological activity of hydroxamic tertiary amines as histone deacetylase inhibitors. Chemmedchem. 7: 694-702. PMID 22278987 DOI: 10.1002/Cmdc.201100531 |
0.819 |
|
2012 |
Piaz FD, Malafronte N, Romano A, Gallotta D, Belisario MA, Bifulco G, Gualtieri MJ, Sanogo R, Tommasi ND, Pisano C. Structural characterization of tetranortriterpenes from Pseudrocedrela kotschyi and Trichilia emetica and study of their activity towards the chaperone Hsp90. Phytochemistry. 75: 78-89. PMID 22226245 DOI: 10.1016/J.Phytochem.2011.12.002 |
0.427 |
|
2012 |
Chini MG, Jones CR, Zampella A, D'Auria MV, Renga B, Fiorucci S, Butts CP, Bifulco G. Quantitative NMR-derived interproton distances combined with quantum mechanical calculations of 13C chemical shifts in the stereochemical determination of conicasterol F, a nuclear receptor ligand from Theonella swinhoei. The Journal of Organic Chemistry. 77: 1489-96. PMID 22201476 DOI: 10.1021/Jo2023763 |
0.651 |
|
2012 |
Cheruku P, Plaza A, Lauro G, Keffer J, Lloyd JR, Bifulco G, Bewley CA. Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor. Journal of Medicinal Chemistry. 55: 735-42. PMID 22168797 DOI: 10.1021/Jm201238P |
0.702 |
|
2012 |
Sepe V, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Debitus C, Fiorucci S, Zampella A. Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei. Journal of Medicinal Chemistry. 55: 84-93. PMID 22126372 DOI: 10.1021/Jm201004P |
0.623 |
|
2012 |
Festa C, De Marino S, D'Auria MV, Deharo E, Gonzalez G, Deyssard C, Petek S, Bifulco G, Zampella A. Gracilioethers E-J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris Tetrahedron. 68: 10157-10163. DOI: 10.1016/J.Tet.2012.09.106 |
0.335 |
|
2011 |
Cipriani S, Mencarelli A, Chini MG, Distrutti E, Renga B, Bifulco G, Baldelli F, Donini A, Fiorucci S. The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis. Plos One. 6: e25637. PMID 22046243 DOI: 10.1371/Journal.Pone.0025637 |
0.59 |
|
2011 |
Monti MC, Chini MG, Margarucci L, Riccio R, Bifulco G, Casapullo A. The binding mode of cladocoran A to the human group IIA phospholipase A(2). Chembiochem : a European Journal of Chemical Biology. 12: 2686-91. PMID 21953776 DOI: 10.1002/Cbic.201100478 |
0.8 |
|
2011 |
De Marino S, Sepe V, D'Auria MV, Bifulco G, Renga B, Petek S, Fiorucci S, Zampella A. Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei. Organic & Biomolecular Chemistry. 9: 4856-62. PMID 21584311 DOI: 10.1039/C1Ob05378G |
0.393 |
|
2011 |
Lauro G, Romano A, Riccio R, Bifulco G. Inverse virtual screening of antitumor targets: pilot study on a small database of natural bioactive compounds. Journal of Natural Products. 74: 1401-7. PMID 21542600 DOI: 10.1021/Np100935S |
0.765 |
|
2011 |
De Marino S, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Fiorucci S, Debitus C, Zampella A. Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors. Journal of Medicinal Chemistry. 54: 3065-75. PMID 21428459 DOI: 10.1021/Jm200169T |
0.647 |
|
2011 |
Festa C, De Marino S, Sepe V, D'Auria MV, Bifulco G, Débitus C, Bucci M, Vellecco V, Zampella A. Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei Organic Letters. 13: 1532-1535. PMID 21341715 DOI: 10.1021/Ol200221N |
0.349 |
|
2011 |
De Simone R, Chini MG, Bruno I, Riccio R, Mueller D, Werz O, Bifulco G. Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents. Journal of Medicinal Chemistry. 54: 1565-75. PMID 21323313 DOI: 10.1021/Jm101238D |
0.834 |
|
2011 |
Sepe V, Bifulco G, Renga B, D'Amore C, Fiorucci S, Zampella A. Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor. Journal of Medicinal Chemistry. 54: 1314-20. PMID 21309576 DOI: 10.1021/Jm101336M |
0.384 |
|
2011 |
Festa C, De Marino S, Dauria MV, Bifulco G, Renga B, Fiorucci S, Petek S, Zampella A. Solomonsterols A and B from Theonella swinhoei. the first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity Journal of Medicinal Chemistry. 54: 401-405. PMID 21141967 DOI: 10.1021/Jm100968B |
0.354 |
|
2011 |
Di Micco S, Mazué F, Daquino C, Spatafora C, Delmas D, Latruffe N, Tringali C, Riccio R, Bifulco G. Structural basis for the potential antitumour activity of DNA-interacting benzo[kl]xanthene lignans. Organic & Biomolecular Chemistry. 9: 701-10. PMID 21079866 DOI: 10.1039/C0Ob00480D |
0.617 |
|
2011 |
Festa C, De Marino S, Sepe V, D'Auria MV, Bifulco G, Andrés R, Terencio MC, Payá M, Debitus C, Zampella A. Perthamides C-F, potent human antipsoriatic cyclopeptides Tetrahedron. 67: 7780-7786. DOI: 10.1016/J.Tet.2011.07.077 |
0.341 |
|
2011 |
Monti MC, Chini MG, Margarucci L, Riccio R, Bifulco G, Casapullo A. Inside Cover: The Binding Mode of Cladocoran A to the Human Group IIA Phospholipase A2 (ChemBioChem 17/2011) Chembiochem. 12: 2522-2522. DOI: 10.1002/Cbic.201190081 |
0.676 |
|
2010 |
Samorì C, Beretta GL, Varchi G, Guerrini A, Di Micco S, Basili S, Bifulco G, Riccio R, Moro S, Bombardelli E, Zunino F, Fontana G. Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach. Chemmedchem. 5: 2006-15. PMID 21069656 DOI: 10.1002/Cmdc.201000369 |
0.602 |
|
2010 |
Chini MG, Terracciano S, Riccio R, Bifulco G, Ciao R, Gaeta C, Troisi F, Neri P. Conformationally locked calixarene-based histone deacetylase inhibitors. Organic Letters. 12: 5382-5. PMID 21038870 DOI: 10.1021/Ol102420B |
0.802 |
|
2010 |
Plaza A, Keffer JL, Bifulco G, Lloyd JR, Bewley CA. Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ. Journal of the American Chemical Society. 132: 9069-77. PMID 20536175 DOI: 10.1021/Ja102100H |
0.371 |
|
2010 |
Plaza A, Bifulco G, Masullo M, Lloyd JR, Keffer JL, Colin PL, Hooper JN, Bell LJ, Bewley CA. Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species. The Journal of Organic Chemistry. 75: 4344-55. PMID 20402515 DOI: 10.1021/Jo100076G |
0.323 |
|
2010 |
Terracciano S, Di Micco S, Bifulco G, Gallinari P, Riccio R, Bruno I. Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222. Bioorganic & Medicinal Chemistry. 18: 3252-60. PMID 20381359 DOI: 10.1016/J.Bmc.2010.03.022 |
0.836 |
|
2010 |
Palermo G, Riccio R, Bifulco G. Effect of electronegative substituents and angular dependence on the heteronuclear spin-spin coupling constant 3J(C-H): an empirical prediction equation derived by density functional theory calculations. The Journal of Organic Chemistry. 75: 1982-91. PMID 20184334 DOI: 10.1021/Jo902704U |
0.531 |
|
2010 |
Colombano G, Travelli C, Galli U, Caldarelli A, Chini MG, Canonico PL, Sorba G, Bifulco G, Tron GC, Genazzani AA. A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry. Journal of Medicinal Chemistry. 53: 616-23. PMID 19961183 DOI: 10.1021/Jm9010669 |
0.702 |
|
2010 |
Pirali T, Faccio V, Mossetti R, Grolla AA, Di Micco S, Bifulco G, Genazzani AA, Tron GC. Synthesis, molecular docking and biological evaluation as HDAC inhibitors of cyclopeptide mimetics by a tandem three-component reaction and intramolecular [3+2] cycloaddition. Molecular Diversity. 14: 109-21. PMID 19475493 DOI: 10.1007/S11030-009-9153-9 |
0.433 |
|
2010 |
Sepe V, D’Auria MV, Bifulco G, Ummarino R, Zampella A. Concise synthesis of AHMHA unit in perthamide C. Structural and stereochemical revision of perthamide C Tetrahedron. 66: 7520-7526. DOI: 10.1016/J.Tet.2010.07.060 |
0.306 |
|
2010 |
Terracciano S, Chini MG, Bifulco G, D'Amico E, Marzocco S, Riccio R, Bruno I. Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors Tetrahedron. 66: 2520-2528. DOI: 10.1016/J.Tet.2010.01.061 |
0.824 |
|
2010 |
Di Micco S, Chini MG, Riccio R, Bifulco G. Quantum Mechanical Calculation of NMR Parameters in the Stereostructural Determination of Natural Products European Journal of Organic Chemistry. 2010: 1411-1434. DOI: 10.1002/Ejoc.200901255 |
0.57 |
|
2009 |
Di Micco S, Vitale R, Pellecchia M, Rega MF, Riva R, Basso A, Bifulco G. Identification of lead compounds as antagonists of protein Bcl-xL with a diversity-oriented multidisciplinary approach. Journal of Medicinal Chemistry. 52: 7856-67. PMID 19852471 DOI: 10.1021/Jm9010687 |
0.415 |
|
2009 |
Monti MC, Chini MG, Margarucci L, Tosco A, Riccio R, Bifulco G, Casapullo A. The molecular mechanism of human group IIA phospholipase A2 inactivation by bolinaquinone. Journal of Molecular Recognition : Jmr. 22: 530-7. PMID 19621421 DOI: 10.1002/Jmr.968 |
0.793 |
|
2009 |
Grolla AA, Podestà V, Chini MG, Di Micco S, Vallario A, Genazzani AA, Canonico PL, Bifulco G, Tron GC, Sorba G, Pirali T. Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases. Journal of Medicinal Chemistry. 52: 2776-85. PMID 19344175 DOI: 10.1021/Jm801529C |
0.682 |
|
2009 |
Chini MG, Scrima M, D'Ursi AM, Bifulco G. Fibril aggregation inhibitory activity of the beta-sheet breaker peptides: a molecular docking approach. Journal of Peptide Science : An Official Publication of the European Peptide Society. 15: 229-34. PMID 19090016 DOI: 10.1002/Psc.1095 |
0.601 |
|
2009 |
Plaza A, Bifulco G, Keffer JL, Lloyd JR, Baker HL, Bewley CA. Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry. The Journal of Organic Chemistry. 74: 504-12. PMID 19072692 DOI: 10.1021/Jo802232U |
0.326 |
|
2009 |
Filosa R, Peduto A, Micco SD, Caprariis Pd, Festa M, Petrella A, Capranico G, Bifulco G. Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry. 17: 13-24. PMID 19058969 DOI: 10.1016/J.Bmc.2008.11.024 |
0.808 |
|
2009 |
Zarra R, Montesarchio D, Coppola C, Bifulco G, Micco SD, Izzo I, Riccardis FD. Design, Synthesis, and Hybridisation of Water-Soluble, Peptoid Nucleic Acid Oligomers Tagged with Thymine European Journal of Organic Chemistry. 2009: 6113-6120. DOI: 10.1002/Ejoc.200900781 |
0.308 |
|
2008 |
Chini MG, Riccio R, Bifulco G. DFT/NMR integrated approach: a valid support to the total synthesis of chiral molecules. Magnetic Resonance in Chemistry : Mrc. 46: 962-8. PMID 18720447 DOI: 10.1002/Mrc.2288 |
0.721 |
|
2008 |
Di Micco S, Terracciano S, Bruno I, Rodriquez M, Riccio R, Taddei M, Bifulco G. Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222. Bioorganic & Medicinal Chemistry. 16: 8635-42. PMID 18715788 DOI: 10.1016/J.Bmc.2008.08.003 |
0.839 |
|
2008 |
Terracciano S, Bruno I, D'Amico E, Bifulco G, Zampella A, Sepe V, Smith CD, Riccio R. Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide. Bioorganic & Medicinal Chemistry. 16: 6580-8. PMID 18508272 DOI: 10.1016/J.Bmc.2008.05.019 |
0.816 |
|
2008 |
Di Micco S, Boger DL, Riccio R, Bifulco G. Structural features of the (+)-yatakemycin/d(GACTAATTGAC)-(GTCAATTAGTC) complex - Quantum mechanical calculation of NMR parameters as a tool for the characterization of ligand/DNA interactions European Journal of Organic Chemistry. 2454-2462. DOI: 10.1002/Ejoc.200701212 |
0.594 |
|
2007 |
Martino L, Virno A, Pagano B, Virgilio A, Di Micco S, Galeone A, Giancola C, Bifulco G, Mayol L, Randazzo A. Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4. Journal of the American Chemical Society. 129: 16048-56. PMID 18052170 DOI: 10.1021/Ja075710K |
0.316 |
|
2007 |
Bifulco G, Dambruoso P, Gomez-Paloma L, Riccio R. Determination of relative configuration in organic compounds by NMR spectroscopy and computational methods. Chemical Reviews. 107: 3744-79. PMID 17649982 DOI: 10.1021/Cr030733C |
0.562 |
|
2007 |
Bassarello C, Bifulco G, Montoro P, Skhirtladze A, Benidze M, Kemertelidze E, Pizza C, Piacente S. Yucca gloriosa: a source of phenolic derivatives with strong antioxidant activity. Journal of Agricultural and Food Chemistry. 55: 6636-42. PMID 17625876 DOI: 10.1021/Jf071131N |
0.339 |
|
2007 |
Bifulco G, Riccio R, Gaeta C, Neri P. Quantum mechanical calculations of conformationally relevant 1H and 13C NMR chemical shifts of N-, O-, and S-substituted calixarene systems. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 7185-94. PMID 17566131 DOI: 10.1002/Chem.200700238 |
0.548 |
|
2007 |
Maulucci N, Chini MG, Micco SD, Izzo I, Cafaro E, Russo A, Gallinari P, Paolini C, Nardi MC, Casapullo A, Riccio R, Bifulco G, Riccardis FD. Molecular insights into azumamide e histone deacetylases inhibitory activity. Journal of the American Chemical Society. 129: 3007-12. PMID 17311384 DOI: 10.1021/Ja0686256 |
0.801 |
|
2007 |
Manzo E, Gavagnin M, Bifulco G, Cimino P, Micco SD, Ciavatta ML, Guo YW, Cimino G. Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela Tetrahedron. 63: 9970-9978. DOI: 10.1016/J.Tet.2007.07.055 |
0.393 |
|
2007 |
Bassarello C, Bifulco G, Montoro P, Skhirtladze A, Kemertelidze E, Pizza C, Piacente S. Gloriosaols A and B, two novel phenolics from Yucca gloriosa: structural characterization and configurational assignment by a combined NMR-quantum mechanical strategy Tetrahedron. 63: 148-154. DOI: 10.1016/J.Tet.2006.10.034 |
0.361 |
|
2007 |
Rosselli S, Bruno M, Maggio A, Bellone G, Formisano C, Mattia CA, Di Micco S, Bifulco G. Two new flavonoids from Bonannia graeca: A DFT-NMR combined approach in solving structures European Journal of Organic Chemistry. 2504-2510. DOI: 10.1002/Ejoc.200600969 |
0.361 |
|
2006 |
Cimino P, Bifulco G, Riccio R, Gomez-Paloma L, Barone V. On the role of stereo-electronic effects in tuning the selectivity and rate of DNA alkylation by duocarmycins. Organic & Biomolecular Chemistry. 4: 1242-51. PMID 16557312 DOI: 10.1039/B514890A |
0.55 |
|
2006 |
Di Marzo M, Casapullo A, Bifulco G, Cimino P, Ligresti A, Di Marzo V, Riccio R, Gomez-Paloma L. Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. Journal of Peptide Science : An Official Publication of the European Peptide Society. 12: 575-91. PMID 16534762 DOI: 10.1002/Psc.754 |
0.737 |
|
2006 |
Rodriquez M, Terracciano S, Cini E, Settembrini G, Bruno I, Bifulco G, Taddei M, Gomez-Paloma L. Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222. Angewandte Chemie (International Ed. in English). 45: 423-7. PMID 16311994 DOI: 10.1002/Anie.200501995 |
0.781 |
|
2006 |
Sepe V, D'Orsi R, Borbone N, D'Auria MV, Bifulco G, Monti MC, Catania A, Zampella A. Callipeltins F–I: new antifungal peptides from the marine sponge Latrunculia sp. Tetrahedron. 62: 833-840. DOI: 10.1016/J.Tet.2005.10.058 |
0.307 |
|
2006 |
Bassarello C, Zampella A, Monti MC, Gomez-Paloma L, D’Auria MV, Riccio R, Bifulco G. Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A European Journal of Organic Chemistry. 2006: 604-609. DOI: 10.1002/Ejoc.200500740 |
0.534 |
|
2005 |
Bifulco G, Gomez-Paloma L, Riccio R, Gaeta C, Troisi F, Neri P. Quantum mechanical calculations of conformationally relevant 1H and 13C NMR chemical shifts of calixarene systems. Organic Letters. 7: 5757-60. PMID 16354059 DOI: 10.1021/Ol052166G |
0.552 |
|
2005 |
Di Micco S, Bassarello C, Bifulco G, Riccio R, Gomez-Paloma L. Differential-frequency saturation transfer difference NMR spectroscopy allows the detection of different ligand-DNA binding modes. Angewandte Chemie (International Ed. in English). 45: 224-8. PMID 16304663 DOI: 10.1002/Anie.200501344 |
0.503 |
|
2005 |
Terracciano S, Bruno I, Bifulco G, Avallone E, Smith CD, Gomez-Paloma L, Riccio R. Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide. Bioorganic & Medicinal Chemistry. 13: 5225-39. PMID 16023351 DOI: 10.1016/J.Bmc.2005.05.042 |
0.816 |
|
2005 |
Dambruoso P, Bassarello C, Bifulco G, Appendino G, Battaglia A, Fontana G, Gomez-Paloma L. Advances in the universal NMR database approach. 2'-substituted taxanes as probes for an improved protocol of diastereomeric differentiation. Organic Letters. 7: 983-6. PMID 15760119 DOI: 10.1021/Ol047600D |
0.352 |
|
2005 |
Dambruoso P, Bassarello C, Bifulco G, Appendino G, Battaglia A, Guerrini A, Fontana G, Gomez-Paloma L. 2′-Methyl taxanes: Synthesis and NMR configurational assignment Tetrahedron Letters. 46: 3411-3415. DOI: 10.1016/J.Tetlet.2005.03.095 |
0.336 |
|
2005 |
Ardá A, Rodríguez J, Nieto RM, Bassarello C, Gomez-Paloma L, Bifulco G, Jiménez C. NMR J-based analysis of nitrogen-containing moieties and application to dysithiazolamide, a new polychlorinated dipeptide from Dysidea sp Tetrahedron. 61: 10093-10098. DOI: 10.1016/J.Tet.2005.08.011 |
0.324 |
|
2005 |
Plaza A, Perrone A, Balestrieri C, Balestrieri ML, Bifulco G, Carbone V, Hamed A, Pizza C, Piacente S. New antiproliferative 14,15-secopregnane glycosides from Solenostemma argel Tetrahedron. 61: 7470-7480. DOI: 10.1016/J.Tet.2005.05.048 |
0.416 |
|
2004 |
Cimino P, Gomez-Paloma L, Duca D, Riccio R, Bifulco G. Comparison of different theory models and basis sets in the calculation of 13C NMR chemical shifts of natural products Magnetic Resonance in Chemistry. 42. PMID 15366038 DOI: 10.1002/Mrc.1410 |
0.547 |
|
2004 |
Terracciano S, Bruno I, Bifulco G, Copper JE, Smith CD, Gomez-Paloma L, Riccio R. Synthesis, conformational analysis, and cytotoxicity of new analogues of the natural cyclodepsipeptide jaspamide. Journal of Natural Products. 67: 1325-31. PMID 15332850 DOI: 10.1021/Np049955B |
0.82 |
|
2004 |
Bassarello C, Lazzaroni S, Bifulco G, Lo Cantore P, Iacobellis NS, Riccio R, Gomez-Paloma L, Evidente A. Tolaasins A--E, five new lipodepsipeptides produced by Pseudomonas tolaasii. Journal of Natural Products. 67: 811-6. PMID 15165142 DOI: 10.1021/Np0303557 |
0.59 |
|
2004 |
Duca D, Bifulco G, Barone G, Casapullo A, Fontana A. SCSA code: Applications on the cyclopeptide renieramide Journal of Chemical Information and Computer Sciences. 44: 1024-1030. PMID 15154771 DOI: 10.1021/Ci034258V |
0.622 |
|
2004 |
Cimino P, Improta R, Bifulco G, Riccio R, Gomez-Paloma L, Barone V. Nucleophilic cyclopropane ring opening in duocarmycin SA derivatives by methanol under acid conditions: a quantum mechanical study in the gas-phase and in solution. The Journal of Organic Chemistry. 69: 2816-24. PMID 15074933 DOI: 10.1021/Jo0303517 |
0.549 |
|
2004 |
Bifulco G, Bassarello C, Riccio R, Gomez-Paloma L. Quantum mechanical calculations of NMR J coupling values in the determination of relative configuration in organic compounds. Organic Letters. 6: 1025-8. PMID 15012091 DOI: 10.1021/Ol049913E |
0.542 |
|
2004 |
Plaza A, Piacente S, Perrone A, Hamed A, Pizza C, Bifulco G. Stemmosides C and D, two novel unusual pregnane glycosides from Solenostemma argel: structural elucidation and configurational study by a combined NMR-quantum mechanical strategy Tetrahedron. 60: 12201-12209. DOI: 10.1016/J.Tet.2004.10.021 |
0.333 |
|
2003 |
Bassarello C, Cimino P, Bifulco G, Boger DL, Smith JA, Chazin WJ, Gomez-Paloma L. NMR Structure of the (+)-CPI-indole/d(GACTAATTGAC)-d(GTCAATTAGTC) Covalent Complex Chembiochem. 4: 1188-1193. PMID 14613110 DOI: 10.1002/Cbic.200300642 |
0.566 |
|
2003 |
Riccio R, Bifulco G, Cimino P, Bassarello C, Gomez-Paloma L. Stereochemical analysis of natural products. Approaches relying on the combination of NMR spectroscopy and computational methods Pure and Applied Chemistry. 75: 295-308. DOI: 10.1351/Pac200375020295 |
0.579 |
|
2003 |
Bifulco G, Gomez-Paloma L, Riccio R. Configurational analysis of the natural product passifloricin A by quantum mechanical 13C NMR GIAO chemical shift calculations Tetrahedron Letters. 44: 7137-7141. DOI: 10.1016/S0040-4039(03)01810-0 |
0.539 |
|
2003 |
Plaza A, Bifulco G, Hamed AI, Pizza C, Piacente S. Argeloside A and B, two novel 14,15-secopregnane glycosides from Solenostemma argel Tetrahedron Letters. 44: 8553-8558. DOI: 10.1016/J.Tetlet.2003.09.132 |
0.359 |
|
2003 |
Bassarello C, Cimino P, Gomez-Paloma L, Riccio R, Bifulco G. Simulation of 2D 1 H homo- and 1 H– 13 C heteronuclear NMR spectra of organic molecules by DFT calculations of spin–spin coupling constants and 1 H and 13 C-chemical shifts Tetrahedron. 59: 9555-9562. DOI: 10.1016/J.Tet.2003.10.001 |
0.557 |
|
2002 |
Barone G, Duca D, Silvestri A, Gomez-Paloma L, Riccio R, Bifulco G. Determination of the relative stereochemistry of flexible organic compounds by Ab initio methods: conformational analysis and Boltzmann-averaged GIAO 13C NMR chemical shifts. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 3240-5. PMID 12203354 DOI: 10.1002/1521-3765(20020715)8:14<3240::Aid-Chem3240>3.0.Co;2-G |
0.56 |
|
2002 |
Barone G, Gomez-Paloma L, Duca D, Silvestri A, Riccio R, Bifulco G. Structure validation of natural products by quantum-mechanical GIAO calculations of 13C NMR chemical shifts Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 3233-3239. PMID 12203353 DOI: 10.1002/1521-3765(20020715)8:14<3233::Aid-Chem3233>3.0.Co;2-0 |
0.575 |
|
2002 |
Cimino P, Bifulco G, Evidente A, Abouzeid M, Riccio R, Gomez-Paloma L. Extension of the J-based configuration analysis to multiple conformer equilibria: an application to sapinofuranone A. Organic Letters. 4: 2779-82. PMID 12153233 DOI: 10.1021/Ol026310Z |
0.556 |
|
2002 |
Ciasullo L, Casapullo A, Cutignano A, Bifulco G, Debitus C, Hooper J, Gomez-Paloma L, Riccio R. Renieramide, a cyclic tripeptide from the Vanuatu sponge Reniera n. sp. Journal of Natural Products. 65: 407-10. PMID 11908992 DOI: 10.1021/Np010383U |
0.722 |
|
2002 |
Piacente S, Bifulco G, Pizza C, Stochmal A, Oleszek W. A novel phenolic spiro derivative, Yuccaone A, from Yucca schidigera bark Tetrahedron Letters. 43: 9133-9136. DOI: 10.1016/S0040-4039(02)02244-X |
0.353 |
|
2002 |
Monica CD, Randazzo A, Bifulco G, Cimino P, Aquino M, Izzo I, Riccardis FD, Gomez-Paloma L. Structural revision of halipeptins: Synthesis of the thiazoline unit and isolation of halipeptin C Tetrahedron Letters. 43: 5707-5710. DOI: 10.1016/S0040-4039(02)01209-1 |
0.397 |
|
2002 |
D'Acquarica I, Di Giovanni MC, Gasparrini F, Misiti D, D'Arrigo C, Fagnano N, Guarnieri D, Iacono G, Bifulco G, Riccio R. Isolation and structure elucidation of four new triterpenoid estersaponins from fruits of Pittosporum tobira AIT Tetrahedron. 58: 10127-10136. DOI: 10.1016/S0040-4020(02)01364-9 |
0.609 |
|
2002 |
Zampella A, Bassarello C, Bifulco G, Gomez-Paloma L, D'Auria MV. Stereochemistry of Sphinxolides and Reidispongiolides. Asymmetric Synthesis of the C17−C22 Fragment of Reidispongiolide A European Journal of Organic Chemistry. 2002: 785-790. DOI: 10.1002/1099-0690(200203)2002:5<785::Aid-Ejoc785>3.0.Co;2-N |
0.335 |
|
2001 |
Randazzo A, Bifulco G, Giannini C, Bucci M, Debitus C, Cirino G, Gomez-Paloma L. Halipeptins A and B: two novel potent anti-inflammatory cyclic depsipeptides from the Vanuatu marine sponge Haliclona species. Journal of the American Chemical Society. 123: 10870-10876. PMID 11686688 DOI: 10.1021/Ja010015C |
0.364 |
|
2001 |
Casapullo A, Cutignano A, Bruno I, Bifulco G, Debitus C, Gomez-Paloma L, Riccio R. Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa. Journal of Natural Products. 64: 1354-6. PMID 11678667 DOI: 10.1021/Np010053+ |
0.791 |
|
2001 |
Cimino P, Bifulco G, Casapullo A, Bruno I, Gomez-Paloma L, Riccio R. Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. Carbohydrate Research. 334: 39-47. PMID 11470249 DOI: 10.1016/S0008-6215(01)00141-0 |
0.779 |
|
2001 |
Bassarello C, Bifulco G, Evidente A, Riccio R, Gomez-Paloma L. Stereochemical studies on ascaulitoxin: a J-based NMR configurational analysis of a nitrogen substituted system Tetrahedron Letters. 42: 8611-8613. DOI: 10.1016/S0040-4039(01)01815-9 |
0.555 |
|
2001 |
Cutignano A, Bruno I, Bifulco G, Casapullo A, Debitus C, Gomez-Paloma L, Riccio R. Dactylolide, a New Cytotoxic Macrolide from the Vanuatu SpongeDactylospongia sp. European Journal of Organic Chemistry. 2001: 775-778. DOI: 10.1002/1099-0690(200102)2001:4<775::Aid-Ejoc775>3.0.Co;2-Z |
0.795 |
|
2001 |
Bassarello C, Bifulco G, Zampella A, D’Auria MV, Riccio R, Gomez-Paloma L. Stereochemical Studies on Sphinxolide: Advances in the J‐Based NMR Determination of the Relative Configuration of Flexible Systems European Journal of Organic Chemistry. 2001: 39-44. DOI: 10.1002/1099-0690(200101)2001:1<39::Aid-Ejoc39>3.0.Co;2-9 |
0.573 |
|
2000 |
Smith JA, Bifulco G, Case DA, Boger DL, Gomez-Paloma L, Chazin WJ. The structural basis for in Situ activation of DNA alkylation by duocarmycin SA Journal of Molecular Biology. 300: 1195-1204. PMID 10903864 DOI: 10.1006/Jmbi.2000.3887 |
0.54 |
|
2000 |
Casapullo A, Bifulco G, Bruno I, Riccio R. New bisindole alkaloids of the topsentin and hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. Journal of Natural Products. 63: 447-51. PMID 10785411 DOI: 10.1021/Np9903292 |
0.816 |
|
2000 |
Cutignano A, Bifulco G, Bruno I, Casapullo A, Gomez-Paloma L, Riccio R. Dragmacidin F: A New Antiviral Bromoindole Alkaloid from the Mediterranean Sponge Halicortex sp. Tetrahedron. 56: 3743-3748. DOI: 10.1016/S0040-4020(00)00281-7 |
0.799 |
|
1998 |
Kragelund BB, Jönsson M, Bifulco G, Chazin WJ, Nilsson H, Finn BE, Linse S. Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation. Biochemistry. 37: 8926-37. PMID 9636034 DOI: 10.1021/Bi9726436 |
0.469 |
|
1998 |
Bifulco G, Galeone A, Nicolaou KC, Chazin WJ, Gomez-Paloma L. Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(Acct) and D(Tcct) High-Affinity Binding Sites Journal of the American Chemical Society. 120: 7183-7191. DOI: 10.2210/Pdb1Qms/Pdb |
0.567 |
|
1996 |
Bifulco G, Galeone A, Gomez-Paloma L, Nicolaou KC, Chazin WJ. Solution structure of the head-to-head dimer of calicheamicin oligosaccharide domain and d(CGTAGGATATCCTACG)2 Journal of the American Chemical Society. 118: 8817-8824. DOI: 10.1021/Ja961525N |
0.596 |
|
1996 |
Riccio R, Kinnel RB, Bifulco G, Scheuer PJ. Kakelokelose, a sulfated mannose polysaccharide with anti-HIV activity from the Pacific tunicate Didemnum molle Tetrahedron Letters. 37: 1979-1982. DOI: 10.1016/0040-4039(96)00262-6 |
0.631 |
|
1995 |
Bifulco G, Bruno I, Minale L, Riccio R, Calignano A, Debitus C. (+/-)-Gelliusines A and B, two diastereomeric brominated tris-indole alkaloids from a deep water new caledonian marine sponge (Gellius or Orina sp.). Journal of Natural Products. 57: 1294-9. PMID 7798965 DOI: 10.1021/Np50111A020 |
0.729 |
|
1995 |
Iorizzi M, Bifulco G, de Riccardis F, Minale L, Riccio R, Zollo F. Starfish saponins, Part 53. A reinvestigation of the polar steroids from the starfish Oreaster reticulatus: isolation of sixteen steroidal oligoglycosides and six polyhydroxysteroids. Journal of Natural Products. 58: 10-26. PMID 7760065 DOI: 10.1021/Np50115A002 |
0.539 |
|
1995 |
Bifulco G, Bruno I, Riccio R, Lavayre J, Bourdy G. Further brominated bis- and tris-indole alkaloids from the deep-water New Caledonian marine sponge Orina Sp. Journal of Natural Products. 58: 1254-60. PMID 7595591 DOI: 10.1021/Np50122A017 |
0.737 |
|
1995 |
Bifulco G, Bruno I, Minale L, Riccio R, Debitus C, Bourdy G, Vassas A, Lavayre J. Bioactive Prenylhydroquinone Sulfates and a Novel C31Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. Journal of Natural Products. 58: 1444-1449. DOI: 10.1021/Np50123A017 |
0.67 |
|
1994 |
Bifulco G, Bruno I, Minale L, Riccio R. Novel HIV-inhibitory halistanol sulfates F-H from a marine sponge, Pseudoaxinissa digitata. Journal of Natural Products. 57: 164-7. PMID 8158159 DOI: 10.1021/Np50103A026 |
0.684 |
|
1993 |
Bifulco G, Bruno I, Paloma LG, Riccio R. Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi Natural Product Letters. 3: 167-171. DOI: 10.1080/10575639308043857 |
0.719 |
|
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