Samuel H. Wilson - Publications

Affiliations: 
Structural Biology NIEHS/NIH, Durham, NC, United States 

297 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Liu Y, Rodriguez Y, Ross RL, Zhao R, Watts JA, Grunseich C, Bruzel A, Li D, Burdick JT, Prasad R, Crouch RJ, Limbach PA, Wilson SH, Cheung VG. RNA abasic sites in yeast and human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32788345 DOI: 10.1073/pnas.2011511117  0.36
2020 Perera L, Beard WA, Pedersen LG, Shock DD, Wilson SH. Preferential DNA Polymerase β Reverse Reaction with Imidodiphosphate. Acs Omega. 5: 15317-15324. PMID 32637805 DOI: 10.1021/acsomega.0c01345  0.88
2020 Batra VK, Wilson SH. Structure of a DNA polymerase abortive complex with the 8OG:dA base pair at the primer terminus. Communications Biology. 3: 348. PMID 32620932 DOI: 10.1038/s42003-020-1080-4  0.6
2020 Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, et al. Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513688 DOI: 10.1073/pnas.1920165117  0.36
2020 Prasad R, Horton JK, Wilson SH. Requirements for PARP-1 covalent crosslinking to DNA (PARP-1 DPC). Dna Repair. 90: 102850. PMID 32438305 DOI: 10.1016/j.dnarep.2020.102850  0.36
2020 Nadalutti CA, Stefanick DF, Zhao ML, Horton JK, Prasad R, Brooks AM, Griffith JD, Wilson SH. Mitochondrial dysfunction and DNA damage accompany enhanced levels of formaldehyde in cultured primary human fibroblasts. Scientific Reports. 10: 5575. PMID 32221313 DOI: 10.1038/s41598-020-61477-2  0.36
2020 Prasad R, Horton JK, Wilson SH. Requirements for PARP-1 covalent crosslinking to DNA (PARP-1 DPC). Dna Repair. 89: 102824. PMID 32151818 DOI: 10.1016/j.dnarep.2020.102824  0.36
2020 Batra VK, Alnajjar KS, Sweasy JB, McKenna CE, Goodman MF, Wilson SH. Revealing an internal stabilization deficiency in the DNA polymerase β K289M cancer variant through combined use of chemical biology and X-ray crystallography. Biochemistry. PMID 31999437 DOI: 10.1021/acs.biochem.9b01072  0.6
2019 Howard MJ, Cavanaugh NA, Batra VK, Shock DD, Beard WA, Wilson SH. DNA polymerase β nucleotide-stabilized template misalignment fidelity depends on local sequence context. The Journal of Biological Chemistry. PMID 31801827 DOI: 10.1074/jbc.RA119.010594  0.88
2019 Janoshazi AK, Horton JK, Zhao ML, Prasad R, Scappini EL, Tucker CJ, Wilson SH. Shining light on the response to repair intermediates in DNA of living cells. Dna Repair. 85: 102749. PMID 31790865 DOI: 10.1016/j.dnarep.2019.102749  0.36
2019 Beard WA, Wilson SH. DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair. The Enzymes. 45: 1-26. PMID 31627875 DOI: 10.1016/bs.enz.2019.08.002  0.88
2019 Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapić-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B. Damage sensor role of UV-DDB during base excision repair. Nature Structural & Molecular Biology. PMID 31332353 DOI: 10.1038/s41594-019-0261-7  0.36
2019 Dai DP, Prasad R, Strauss PR, Wilson SH. The Pol β variant containing exon α is deficient in DNA polymerase but has full dRP lyase activity. Scientific Reports. 9: 9928. PMID 31289286 DOI: 10.1038/s41598-019-45846-0  0.36
2019 Beard WA, Horton JK, Prasad R, Wilson SH. Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism. Annual Review of Biochemistry. 88: 137-162. PMID 31220977 DOI: 10.1146/annurev-biochem-013118-111315  0.88
2019 Howard MJ, Foley KG, Shock DD, Batra VK, Wilson SH. Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA Polymerase ß. The Journal of Biological Chemistry. PMID 30885943 DOI: 10.1074/jbc.RA118.006809  0.6
2019 Smith MR, Shock DD, Beard WA, Greenberg MM, Freudenthal BD, Wilson SH. A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Research. PMID 30649431 DOI: 10.1093/nar/gkz002  0.88
2018 Prasad R, Horton JK, Dai DP, Wilson SH. Repair pathway for PARP-1 DNA-protein crosslinks. Dna Repair. PMID 30466837 DOI: 10.1016/j.dnarep.2018.11.004  0.36
2018 DeRose EF, Kirby TW, Mueller GA, Beard WA, Wilson SH, London RE. Transitions in DNA polymerase β μs-ms dynamics related to substrate binding and catalysis. Nucleic Acids Research. PMID 29917149 DOI: 10.1093/nar/gky503  0.88
2018 Oertell K, Kashemirov BA, Negahbani A, Minard C, Haratipour P, Alnajjar KS, Sweasy JB, Batra VK, Beard WA, Wilson SH, McKenna CE, Goodman MF. Probing DNA base-dependent leaving group kinetic effects on the DNA polymerase transition state. Biochemistry. PMID 29889506 DOI: 10.1021/acs.biochem.8b00417  0.88
2018 Batra VK, Oertell K, Beard WA, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Mapping functional substrate-enzyme interactions in the pol β active site through chemical biology: Structural responses to acidity modification of incoming dNTPs. Biochemistry. PMID 29874056 DOI: 10.1021/acs.biochem.8b00418  0.88
2018 Horton JK, Stefanick DF, Çağlayan M, Zhao ML, Janoshazi AK, Prasad R, Gassman NR, Wilson SH. XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity. Dna Repair. 64: 26-33. PMID 29477978 DOI: 10.1016/j.dnarep.2018.02.004  0.36
2017 Liu L, Kong M, Gassman NR, Freudenthal BD, Prasad R, Zhen S, Watkins SC, Wilson SH, Van Houten B. PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1. Nucleic Acids Research. PMID 29121337 DOI: 10.1093/nar/gkx1047  0.36
2017 Prasad R, Çağlayan M, Dai DP, Nadalutti CA, Zhao ML, Gassman NR, Janoshazi AK, Stefanick DF, Horton JK, Krasich R, Longley MJ, Copeland WC, Griffith JD, Wilson SH. DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria. Dna Repair. 60: 77-88. PMID 29100041 DOI: 10.1016/j.dnarep.2017.10.011  0.36
2017 Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH. Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Nucleic Acids Research. 45: 10079-10088. PMID 28973450 DOI: 10.1093/nar/gkx654  0.36
2017 Rodriguez Y, Howard MJ, Cuneo MJ, Prasad R, Wilson SH. Unencumbered Pol β lyase activity in nucleosome core particles. Nucleic Acids Research. 45: 8901-8915. PMID 28911106 DOI: 10.1093/nar/gkx593  0.36
2017 Jamsen JA, Beard WA, Pedersen LC, Shock DD, Moon AF, Krahn JM, Bebenek K, Kunkel TA, Wilson SH. Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nature Communications. 8: 253. PMID 28811466 DOI: 10.1038/s41467-017-00271-7  0.88
2017 Shock DD, Freudenthal BD, Beard WA, Wilson SH. Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction. Nature Chemical Biology. PMID 28759020 DOI: 10.1038/nchembio.2450  0.88
2017 Perera L, Freudenthal BD, Beard WA, Pedersen LG, Wilson SH. Revealing the role of the product metal in DNA polymerase β catalysis. Nucleic Acids Research. PMID 28108654 DOI: 10.1093/nar/gkw1363  0.88
2016 Perera L, Beard WA, Pedersen LG, Wilson SH. Hiding in Plain Sight: The Bimetallic Magnesium Covalent Bond in Enzyme Active Sites. Inorganic Chemistry. PMID 27976880 DOI: 10.1021/acs.inorgchem.6b02189  0.88
2016 Prasad R, Poltoratsky V, Hou EW, Wilson SH. Rev1 is a base excision repair enzyme with 5'-deoxyribose phosphate lyase activity. Nucleic Acids Research. PMID 27683219 DOI: 10.1093/nar/gkw869  0.36
2016 Sassa A, Ҫağlayan M, Rodriguez Y, Beard WA, Wilson SH, Nohmi T, Honma M, Yasui M. Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine. The Journal of Biological Chemistry. PMID 27660390 DOI: 10.1074/jbc.M116.738732  0.88
2016 Batra VK, Beard WA, Pedersen LC, Wilson SH. Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure (London, England : 1993). PMID 27642161 DOI: 10.1016/j.str.2016.08.006  0.88
2016 Gassman NR, Coskun E, Jaruga P, Dizdaroglu M, Wilson SH. Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts. Environmental Health Perspectives. PMID 27082013 DOI: 10.1289/EHP237  0.88
2016 Kim T, Freudenthal BD, Beard WA, Wilson SH, Schlick T. Insertion of oxidized nucleotide triggers rapid DNA polymerase opening. Nucleic Acids Research. PMID 27034465 DOI: 10.1093/nar/gkw174  0.88
2015 Çağlayan M, Wilson SH. Reprint of "Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair". Dna Repair. PMID 26596511 DOI: 10.1016/j.dnarep.2015.11.002  0.88
2015 Wilson SH, Friedberg E. Editorial. Dna Repair. 35: v. PMID 26574139 DOI: 10.1016/S1568-7864(15)00215-3  0.88
2015 Çağlayan M, Wilson SH. Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair. Dna Repair. 35: 85-89. PMID 26466358 DOI: 10.1016/j.dnarep.2015.09.010  0.88
2015 Freudenthal BD, Beard WA, Cuneo MJ, Dyrkheeva NS, Wilson SH. Capturing snapshots of APE1 processing DNA damage. Nature Structural & Molecular Biology. PMID 26458045 DOI: 10.1038/nsmb.3105  0.88
2015 Perera L, Freudenthal BD, Beard WA, Shock DD, Pedersen LG, Wilson SH. Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse. Proceedings of the National Academy of Sciences of the United States of America. 112: E5228-36. PMID 26351676 DOI: 10.1073/pnas.1511207112  0.88
2015 Kirby TW, Gassman NR, Smith CE, Pedersen LC, Gabel SA, Sobhany M, Wilson SH, London RE. Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Scientific Reports. 5: 13405. PMID 26304019 DOI: 10.1038/srep13405  0.88
2015 Fedeles BI, Freudenthal BD, Yau E, Singh V, Chang SC, Li D, Delaney JC, Wilson SH, Essigmann JM. Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: E4571-80. PMID 26243878 DOI: 10.1073/pnas.1507709112  0.88
2015 Prasad R, Dyrkheeva N, Williams J, Wilson SH. Mammalian Base Excision Repair: Functional Partnership between PARP-1 and APE1 in AP-Site Repair. Plos One. 10: e0124269. PMID 26020771 DOI: 10.1371/journal.pone.0124269  0.36
2015 Freudenthal BD, Beard WA, Wilson SH. New structural snapshots provide molecular insights into the mechanism of high fidelity DNA synthesis. Dna Repair. PMID 26002198 DOI: 10.1016/j.dnarep.2015.04.007  0.88
2015 Gassman NR, Wilson SH. Micro-irradiation tools to visualize base excision repair and single-strand break repair. Dna Repair. 31: 52-63. PMID 25996408 DOI: 10.1016/j.dnarep.2015.05.001  0.88
2015 Kadina AP, Kashemirov BA, Oertell K, Batra VK, Wilson SH, Goodman MF, McKenna CE. Two Scaffolds from Two Flips: (α,β)/(β,γ) CH2/NH "Met-Im" Analogues of dTTP. Organic Letters. 17: 2586-9. PMID 25970636 DOI: 10.1021/acs.orglett.5b00799  0.88
2015 Beard WA, Wilson SH. Structures of human DNA polymerases ν and θ expose their end game. Nature Structural & Molecular Biology. 22: 273-5. PMID 25837870 DOI: 10.1038/nsmb.3006  0.88
2015 Gassman NR, Coskun E, Stefanick DF, Horton JK, Jaruga P, Dizdaroglu M, Wilson SH. Bisphenol a promotes cell survival following oxidative DNA damage in mouse fibroblasts. Plos One. 10: e0118819. PMID 25693136 DOI: 10.1371/journal.pone.0118819  0.88
2015 Ça?layan M, Horton JK, Prasad R, Wilson SH. Complementation of aprataxin deficiency by base excision repair enzymes. Nucleic Acids Research. 43: 2271-81. PMID 25662216 DOI: 10.1093/nar/gkv079  0.36
2015 Horton JK, Gassman NR, Dunigan BD, Stefanick DF, Wilson SH. DNA polymerase β-dependent cell survival independent of XRCC1 expression. Dna Repair. 26: 23-9. PMID 25541391 DOI: 10.1016/j.dnarep.2014.11.008  0.88
2015 Freudenthal BD, Beard WA, Perera L, Shock DD, Kim T, Schlick T, Wilson SH. Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature. 517: 635-9. PMID 25409153 DOI: 10.1038/nature13886  0.88
2015 Hanawalt PC, Wilson SH. Preface Dna Repair. DOI: 10.1016/j.dnarep.2015.06.001  0.88
2014 Perera L, Beard WA, Pedersen LG, Wilson SH. Applications of quantum mechanical/molecular mechanical methods to the chemical insertion step of DNA and RNA polymerization. Advances in Protein Chemistry and Structural Biology. 97: 83-113. PMID 25458356 DOI: 10.1016/bs.apcsb.2014.10.001  0.88
2014 Beard WA, Shock DD, Batra VK, Prasad R, Wilson SH. Substrate-induced DNA polymerase β activation. The Journal of Biological Chemistry. 289: 31411-22. PMID 25261471 DOI: 10.1074/jbc.M114.607432  0.88
2014 Wilson SH. Reflections on the Superfund Research Program: a tribute to its Founding Director, William A. Suk. Dna Repair. 22: v-viii. PMID 25246422 DOI: 10.1016/S1568-7864(14)00232-8  0.88
2014 Bienstock RJ, Beard WA, Wilson SH. Phylogenetic analysis and evolutionary origins of DNA polymerase X-family members. Dna Repair. 22: 77-88. PMID 25112931 DOI: 10.1016/j.dnarep.2014.07.003  0.88
2014 Hanawalt PC, Wilson SH. Coincidentally, this first issue marks the 50th anniversary of the seminal discovery of the excision-repair of damaged DNA. Preface. Dna Repair. 19: 1-2. PMID 24909491 DOI: 10.1016/j.dnarep.2014.05.004  0.88
2014 CaÄŸlayan M, Batra VK, Sassa A, Prasad R, Wilson SH. Role of polymerase β in complementing aprataxin deficiency during abasic-site base excision repair. Nature Structural & Molecular Biology. 21: 497-9. PMID 24777061 DOI: 10.1038/nsmb.2818  0.6
2014 Prasad R, Horton JK, Chastain PD, Gassman NR, Freudenthal BD, Hou EW, Wilson SH. Suicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair. Nucleic Acids Research. 42: 6337-51. PMID 24771347 DOI: 10.1093/nar/gku288  0.88
2014 Horton JK, Stefanick DF, Prasad R, Gassman NR, Kedar PS, Wilson SH. Base excision repair defects invoke hypersensitivity to PARP inhibition. Molecular Cancer Research : McR. 12: 1128-39. PMID 24770870 DOI: 10.1158/1541-7786.MCR-13-0502  0.88
2014 Beard WA, Wilson SH. Structure and mechanism of DNA polymerase β. Biochemistry. 53: 2768-80. PMID 24717170 DOI: 10.1021/bi500139h  0.88
2014 Sassa A, ÇaÄŸlayan M, Dyrkheeva NS, Beard WA, Wilson SH. Base excision repair of tandem modifications in a methylated CpG dinucleotide. The Journal of Biological Chemistry. 289: 13996-4008. PMID 24695738 DOI: 10.1074/jbc.M114.557769  0.88
2014 Kirby TW, Derose EF, Beard WA, Shock DD, Wilson SH, London RE. Substrate rescue of DNA polymerase β containing a catastrophic L22P mutation. Biochemistry. 53: 2413-22. PMID 24655288 DOI: 10.1021/bi5001855  0.88
2014 Oertell K, Chamberlain BT, Wu Y, Ferri E, Kashemirov BA, Beard WA, Wilson SH, McKenna CE, Goodman MF. Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration. Biochemistry. 53: 1842-8. PMID 24580380 DOI: 10.1021/bi500101z  0.88
2014 Li Y, Freudenthal BD, Beard WA, Wilson SH, Schlick T. Optimal and variant metal-ion routes in DNA polymerase β's conformational pathways. Journal of the American Chemical Society. 136: 3630-9. PMID 24511902 DOI: 10.1021/ja412701f  0.88
2014 Freudenthal BD, Beard WA, Wilson SH. Watching a DNA polymerase in action. Cell Cycle (Georgetown, Tex.). 13: 691-2. PMID 24424116 DOI: 10.4161/cc.27789  0.88
2014 Wu S, Beard WA, Pedersen LG, Wilson SH. Structural comparison of DNA polymerase architecture suggests a nucleotide gateway to the polymerase active site. Chemical Reviews. 114: 2759-74. PMID 24359247 DOI: 10.1021/cr3005179  0.88
2013 Horton JK, Wilson SH. Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity. Frontiers in Oncology. 3: 257. PMID 24137565 DOI: 10.3389/fonc.2013.00257  0.88
2013 Chary P, Beard WA, Wilson SH, Lloyd RS. Inhibition of HIV-1 reverse transcriptase-catalyzed synthesis by intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide adducts. Plos One. 8: e72131. PMID 24069141 DOI: 10.1371/journal.pone.0072131  0.88
2013 Sassa A, Beard WA, Shock DD, Wilson SH. Steady-state, pre-steady-state, and single-turnover kinetic measurement for DNA glycosylase activity Journal of Visualized Experiments : Jove. PMID 23995844  0.88
2013 An C, Beard WA, Chen D, Wilson SH, Makridakis NM. Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer. International Journal of Oncology. 43: 1131-40. PMID 23877444 DOI: 10.3892/ijo.2013.2022  0.88
2013 Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. Dna Repair. 12: 774-85. PMID 23871146 DOI: 10.1016/j.dnarep.2013.06.004  0.88
2013 Freudenthal BD, Beard WA, Shock DD, Wilson SH. Observing a DNA polymerase choose right from wrong. Cell. 154: 157-68. PMID 23827680 DOI: 10.1016/j.cell.2013.05.048  0.88
2013 Masaoka A, Gassman NR, Horton JK, Kedar PS, Witt KL, Hobbs CA, Kissling GE, Tano K, Asagoshi K, Wilson SH. Interaction between DNA Polymerase β and BRCA1. Plos One. 8: e66801. PMID 23826138 DOI: 10.1371/journal.pone.0066801  0.88
2013 Vaidyanathan VG, Liang F, Beard WA, Shock DD, Wilson SH, Cho BP. Insights into the conformation of aminofluorene-deoxyguanine adduct in a DNA polymerase active site. The Journal of Biological Chemistry. 288: 23573-85. PMID 23798703 DOI: 10.1074/jbc.M113.476150  0.88
2013 Batra VK, Perera L, Lin P, Shock DD, Beard WA, Pedersen LC, Pedersen LG, Wilson SH. Amino acid substitution in the active site of DNA polymerase β explains the energy barrier of the nucleotidyl transfer reaction. Journal of the American Chemical Society. 135: 8078-88. PMID 23647366 DOI: 10.1021/ja403842j  0.88
2013 Freudenthal BD, Beard WA, Wilson SH. DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Nucleic Acids Research. 41: 1848-58. PMID 23267011 DOI: 10.1093/nar/gks1276  0.88
2013 Horton JK, Wilson SH. Predicting enhanced cell killing through PARP inhibition. Molecular Cancer Research : McR. 11: 13-8. PMID 23193155 DOI: 10.1158/1541-7786.MCR-12-0512  0.88
2013 Rajan R, Prasad R, Taneja B, Wilson SH, Mondragón A. Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies. Nucleic Acids Research. 41: 657-66. PMID 23125368 DOI: 10.1093/nar/gks1017  0.88
2012 Schlick T, Arora K, Beard WA, Wilson SH. Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms. Theoretical Chemistry Accounts. 131: 1287. PMID 23459563 DOI: 10.1007/s00214-012-1287-7  0.88
2012 Gassman NR, Stefanick DF, Kedar PS, Horton JK, Wilson SH. Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts. Plos One. 7: e49301. PMID 23145148 DOI: 10.1371/journal.pone.0049301  0.88
2012 Heacock M, Poltoratsky V, Prasad R, Wilson SH. Evidence for Abasic Site Sugar Phosphate-Mediated Cytotoxicity in Alkylating Agent Treated Saccharomyces cerevisiae Plos One. 7. PMID 23144716 DOI: 10.1371/journal.pone.0047945  0.88
2012 Chary P, Beard WA, Wilson SH, Lloyd RS. DNA polymerase β gap-filling translesion DNA synthesis. Chemical Research in Toxicology. 25: 2744-54. PMID 23121263 DOI: 10.1021/tx300368f  0.88
2012 Oertell K, Wu Y, Zakharova VM, Kashemirov BA, Shock DD, Beard WA, Wilson SH, McKenna CE, Goodman MF. Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β. Biochemistry. 51: 8491-501. PMID 23043620 DOI: 10.1021/bi3010335  0.88
2012 Prasad R, Williams JG, Hou EW, Wilson SH. Pol β associated complex and base excision repair factors in mouse fibroblasts. Nucleic Acids Research. 40: 11571-82. PMID 23042675 DOI: 10.1093/nar/gks898  0.36
2012 Sassa A, Beard WA, Prasad R, Wilson SH. DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase. The Journal of Biological Chemistry. 287: 36702-10. PMID 22989888 DOI: 10.1074/jbc.M112.397786  0.88
2012 Freudenthal BD, Beard WA, Wilson SH. Structures of dNTP intermediate states during DNA polymerase active site assembly. Structure (London, England : 1993). 20: 1829-37. PMID 22959623 DOI: 10.1016/j.str.2012.08.008  0.88
2012 Masaoka A, Gassman NR, Kedar PS, Prasad R, Hou EW, Horton JK, Bustin M, Wilson SH. HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts. The Journal of Biological Chemistry. 287: 27648-58. PMID 22736760 DOI: 10.1074/jbc.M112.370759  0.88
2012 Wu Y, Zakharova VM, Kashemirov BA, Goodman MF, Batra VK, Wilson SH, McKenna CE. β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures, and absolute configurations of new stereochemical probes for DNA polymerases. Journal of the American Chemical Society. 134: 8734-7. PMID 22397499 DOI: 10.1021/ja300218x  0.88
2012 Chamberlain BT, Batra VK, Beard WA, Kadina AP, Shock DD, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β. Chembiochem : a European Journal of Chemical Biology. 13: 528-30. PMID 22315190 DOI: 10.1002/cbic.201100738  0.88
2012 Liu Y, Wilson SH. DNA base excision repair: A mechanism of trinucleotide repeat expansion Trends in Biochemical Sciences. 37: 162-172. PMID 22285516 DOI: 10.1016/j.tibs.2011.12.002  0.88
2012 Batra VK, Shock DD, Beard WA, McKenna CE, Wilson SH. Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion. Proceedings of the National Academy of Sciences of the United States of America. 109: 113-8. PMID 22178760 DOI: 10.1073/pnas.1112235108  0.88
2012 Kirby TW, DeRose EF, Cavanaugh NA, Beard WA, Shock DD, Mueller GA, Wilson SH, London RE. Metal-induced DNA translocation leads to DNA polymerase conformational activation. Nucleic Acids Research. 40: 2974-83. PMID 22169953 DOI: 10.1093/nar/gkr1218  0.88
2012 Asagoshi K, Lehmann W, Braithwaite EK, Santana-Santos L, Prasad R, Freedman JH, Van Houten B, Wilson SH. Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β. Nucleic Acids Research. 40: 670-81. PMID 21917855 DOI: 10.1093/nar/gkr727  0.36
2011 Cavanaugh NA, Beard WA, Batra VK, Perera L, Pedersen LG, Wilson SH. Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. The Journal of Biological Chemistry. 286: 31650-60. PMID 21733843 DOI: 10.1074/jbc.M111.253401  0.88
2011 Asagoshi K, Wilson SH. Base-excision repair: Role of DNA polymerase β in late-stage base excision repair Current Cancer Research. 6: 297-319. DOI: 10.1007/978-1-61737-995-6_14  0.88
2010 Khodyreva SN, Prasad R, Ilina ES, Sukhanova MV, Kutuzov MM, Liu Y, Hou EW, Wilson SH, Lavrik OI. Apurinic/apyrimidinic (AP) site recognition by the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1). Proceedings of the National Academy of Sciences of the United States of America. 107: 22090-5. PMID 21127267 DOI: 10.1073/pnas.1009182107  0.88
2010 Prasad R, Shock DD, Beard WA, Wilson SH. Substrate channeling in mammalian base excision repair pathways: passing the baton. The Journal of Biological Chemistry. 285: 40479-88. PMID 20952393 DOI: 10.1074/jbc.M110.155267  0.88
2010 Wilson SH, Beard WA, Shock DD, Batra VK, Cavanaugh NA, Prasad R, Hou EW, Liu Y, Asagoshi K, Horton JK, Stefanick DF, Kedar PS, Carrozza MJ, Masaoka A, Heacock ML. Base excision repair and design of small molecule inhibitors of human DNA polymerase β. Cellular and Molecular Life Sciences : Cmls. 67: 3633-47. PMID 20844920 DOI: 10.1007/s00018-010-0489-1  0.88
2010 Poltoratsky V, Heacock M, Kissling GE, Prasad R, Wilson SH. Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break Molecular Immunology. 48: 164-170. PMID 20828826 DOI: 10.1016/j.molimm.2010.08.013  0.88
2010 Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA. Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proceedings of the National Academy of Sciences of the United States of America. 107: 15693-8. PMID 20724659 DOI: 10.1073/pnas.1007430107  0.88
2010 Beard WA, Batra VK, Wilson SH. DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 703: 18-23. PMID 20696268 DOI: 10.1016/j.mrgentox.2010.07.013  0.88
2010 Heacock ML, Stefanick DF, Horton JK, Wilson SH. Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks. Dna Repair. 9: 929-36. PMID 20573551 DOI: 10.1016/j.dnarep.2010.05.007  0.88
2010 Batra VK, Beard WA, Hou EW, Pedersen LC, Prasad R, Wilson SH. Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Nature Structural & Molecular Biology. 17: 889-90. PMID 20526335 DOI: 10.1038/nsmb.1852  0.88
2010 Cavanaugh NA, Beard WA, Wilson SH. DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding. The Journal of Biological Chemistry. 285: 24457-65. PMID 20519499 DOI: 10.1074/jbc.M110.132407  0.88
2010 Batra VK, Pedersen LC, Beard WA, Wilson SH, Kashemirov BA, Upton TG, Goodman MF, McKenna CE. Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. Journal of the American Chemical Society. 132: 7617-25. PMID 20465217 DOI: 10.1021/ja909370k  0.88
2010 Liu Y, Prasad R, Wilson SH. HMGB1: Roles in base excision repair and related function Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. 1799: 119-130. PMID 20123074 DOI: 10.1016/j.bbagrm.2009.11.008  0.88
2010 Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA polymerase beta-dependent long patch base excision repair in living cells. Dna Repair. 9: 109-19. PMID 20006562 DOI: 10.1016/j.dnarep.2009.11.002  0.88
2009 Beard WA, Shock DD, Batra VK, Pedersen LC, Wilson SH. DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". The Journal of Biological Chemistry. 284: 31680-9. PMID 19759017 DOI: 10.1074/jbc.M109.029843  0.88
2009 Masaoka A, Horton JK, Beard WA, Wilson SH. DNA polymerase beta and PARP activities in base excision repair in living cells. Dna Repair. 8: 1290-9. PMID 19748837 DOI: 10.1016/j.dnarep.2009.08.004  0.88
2009 Dorjsuren D, Wilson DM, Beard WA, McDonald JP, Austin CP, Woodgate R, Wilson SH, Simeonov A. A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases. Nucleic Acids Research. 37: e128. PMID 19684079 DOI: 10.1093/nar/gkp641  0.88
2009 Liu Y, Prasad R, Beard WA, Hou EW, Horton JK, McMurray CT, Wilson SH. Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion. The Journal of Biological Chemistry. 284: 28352-66. PMID 19674974 DOI: 10.1074/jbc.M109.050286  0.88
2009 Yoshizawa K, Jelezcova E, Brown AR, Foley JF, Nyska A, Cui X, Hofseth LJ, Maronpot RM, Wilson SH, Sepulveda AR, Sobol RW. Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. Plos One. 4: e6493. PMID 19654874 DOI: 10.1371/journal.pone.0006493  0.88
2009 Upton TG, Kashemirov BA, McKenna CE, Goodman MF, Prakash GK, Kultyshev R, Batra VK, Shock DD, Pedersen LC, Beard WA, Wilson SH. Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Organic Letters. 11: 1883-6. PMID 19351147 DOI: 10.1021/ol701755k  0.88
2009 Prasad R, Longley MJ, Sharief FS, Hou EW, Copeland WC, Wilson SH. Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro. Nucleic Acids Research. 37: 1868-77. PMID 19188258 DOI: 10.1093/nar/gkp035  0.88
2008 Liang F, Jain N, Hutchens T, Shock DD, Beard WA, Wilson SH, Chiarelli MP, Cho BP. Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT. Journal of Medicinal Chemistry. 51: 6460-70. PMID 18811136 DOI: 10.1021/jm800692a  0.88
2008 Allen D, Herbert DC, McMahan CA, Rotrekl V, Sobol RW, Wilson SH, Walter CA. Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Biology of Reproduction. 79: 824-31. PMID 18650495 DOI: 10.1095/biolreprod.108.069104  0.88
2008 Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, ... ... Wilson SH, et al. Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7219-30. PMID 18614692 DOI: 10.1523/JNEUROSCI.0940-08.2008  0.88
2008 Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Molecular Cell. 30: 315-24. PMID 18471977 DOI: 10.1016/j.molcel.2008.02.025  0.88
2008 Poltoratsky V, Horton JK, Prasad R, Beard WA, Woodgate R, Wilson SH. Negligible impact of pol iota expression on the alkylation sensitivity of pol beta-deficient mouse fibroblast cells. Dna Repair. 7: 830-3. PMID 18434259 DOI: 10.1016/j.dnarep.2008.02.013  0.88
2008 Lin P, Batra VK, Pedersen LC, Beard WA, Wilson SH, Pedersen LG. Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 5670-4. PMID 18391201 DOI: 10.1073/pnas.0801257105  0.88
2008 Sucato CA, Upton TG, Kashemirov BA, Osuna J, Oertell K, Beard WA, Wilson SH, Florián J, Warshel A, McKenna CE, Goodman MF. DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Biochemistry. 47: 870-9. PMID 18161950 DOI: 10.1021/bi7014162  0.88
2008 Xiang Y, Goodman MF, Beard WA, Wilson SH, Warshel A. Exploring the role of large conformational changes in the fidelity of DNA polymerase beta. Proteins. 70: 231-47. PMID 17671961 DOI: 10.1002/prot.21668  0.88
2007 McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH. (R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. Journal of the American Chemical Society. 129: 15412-3. PMID 18031037 DOI: 10.1021/ja072127v  0.88
2007 Prasad R, Liu Y, Deterding LJ, Poltoratsky VP, Kedar PS, Horton JK, Kanno S, Asagoshi K, Hou EW, Khodyreva SN, Lavrik OI, Tomer KB, Yasui A, Wilson SH. HMGB1 is a cofactor in mammalian base excision repair. Molecular Cell. 27: 829-41. PMID 17803946 DOI: 10.1016/j.molcel.2007.06.029  0.88
2007 Hou EW, Prasad R, Asagoshi K, Masaoka A, Wilson SH. Comparative assessment of plasmid and oligonucleotide DNA substrates in measurement of in vitro base excision repair activity. Nucleic Acids Research. 35: e112. PMID 17720705 DOI: 10.1093/nar/gkm639  0.36
2007 Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC. The X family portrait: structural insights into biological functions of X family polymerases. Dna Repair. 6: 1709-25. PMID 17631059 DOI: 10.1016/j.dnarep.2007.05.009  0.88
2007 Nakanishi S, Prasad R, Wilson SH, Smerdon M. Different structural states in oligonucleosomes are required for early versus late steps of base excision repair. Nucleic Acids Research. 35: 4313-21. PMID 17576692 DOI: 10.1093/nar/gkm436  0.36
2007 Tano K, Nakamura J, Asagoshi K, Arakawa H, Sonoda E, Braithwaite EK, Prasad R, Buerstedde JM, Takeda S, Watanabe M, Wilson SH. Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. Dna Repair. 6: 869-75. PMID 17363341 DOI: 10.1016/j.dnarep.2007.01.011  0.36
2007 Liu Y, Prasad R, Beard WA, Kedar PS, Hou EW, Shock DD, Wilson SH. Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta. The Journal of Biological Chemistry. 282: 13532-41. PMID 17355977 DOI: 10.1074/jbc.M611295200  0.88
2007 Wang Y, Reddy S, Beard WA, Wilson SH, Schlick T. Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. Biophysical Journal. 92: 3063-70. PMID 17293403 DOI: 10.1529/biophysj.106.092106  0.88
2007 Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martínek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florián J, Warshel A, Goodman MF. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry. 46: 461-71. PMID 17209556 DOI: 10.1021/bi061517b  0.88
2007 Oelschlaeger P, Klahn M, Beard WA, Wilson SH, Warshel A. Magnesium-cationic dummy atom molecules enhance representation of DNA polymerase beta in molecular dynamics simulations: improved accuracy in studies of structural features and mutational effects. Journal of Molecular Biology. 366: 687-701. PMID 17174326 DOI: 10.1016/j.jmb.2006.10.095  0.88
2007 Poltoratsky V, Prasad R, Horton JK, Wilson SH. Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines. Dna Repair. 6: 244-53. PMID 17127106 DOI: 10.1016/j.dnarep.2006.10.003  0.36
2007 Horton JK, Wilson SH. Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency Dna Repair. 6: 530-543. PMID 17113833 DOI: 10.1016/j.dnarep.2006.10.016  0.88
2006 Radhakrishnan R, Arora K, Wang Y, Beard WA, Wilson SH, Schlick T. Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Biochemistry. 45: 15142-56. PMID 17176036 DOI: 10.1021/bi061353z  0.88
2006 Batra VK, Shock DD, Prasad R, Beard WA, Hou EW, Pedersen LC, Sayer JM, Yagi H, Kumar S, Jerina DM, Wilson SH. Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Proceedings of the National Academy of Sciences of the United States of America. 103: 17231-6. PMID 17079493 DOI: 10.1073/pnas.0605069103  0.88
2006 Yoshimura M, Kohzaki M, Nakamura J, Asagoshi K, Sonoda E, Hou E, Prasad R, Wilson SH, Tano K, Yasui A, Lan L, Seki M, Wood RD, Arakawa H, Buerstedde JM, et al. Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Molecular Cell. 24: 115-25. PMID 17018297 DOI: 10.1016/j.molcel.2006.07.032  0.36
2006 Lin P, Pedersen LC, Batra VK, Beard WA, Wilson SH, Pedersen LG. Energy analysis of chemistry for correct insertion by DNA polymerase beta. Proceedings of the National Academy of Sciences of the United States of America. 103: 13294-9. PMID 16938895 DOI: 10.1073/pnas.0606006103  0.88
2006 Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR. Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Research. 66: 7460-5. PMID 16885342 DOI: 10.1158/0008-5472.CAN-06-1177  0.88
2006 Beard WA, Prasad R, Wilson SH. Activities and Mechanism of DNA Polymerase β Methods in Enzymology. 408: 91-107. PMID 16793365 DOI: 10.1016/S0076-6879(06)08007-4  0.88
2006 Gao G, Prasad R, Lodwig SN, Unkefer CJ, Beard WA, Wilson SH, London RE. Determination of lysine pK values using [5-13C]lysine: application to the lyase domain of DNA Pol beta. Journal of the American Chemical Society. 128: 8104-5. PMID 16787052 DOI: 10.1021/ja061473u  0.88
2006 Batra VK, Beard WA, Shock DD, Krahn JM, Pedersen LC, Wilson SH. Magnesium-induced assembly of a complete DNA polymerase catalytic complex. Structure (London, England : 1993). 14: 757-66. PMID 16615916 DOI: 10.1016/j.str.2006.01.011  0.88
2006 Harrigan JA, Wilson DM, Prasad R, Opresko PL, Beck G, May A, Wilson SH, Bohr VA. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Nucleic Acids Research. 34: 745-54. PMID 16449207 DOI: 10.1093/nar/gkj475  0.88
2006 Liu Y, Prasad R, Wilson SH. DNA repair models for understanding triplet repeat instability Genetic Instabilities and Neurological Diseases, Second Edition. 667-678. DOI: 10.1016/B978-012369462-1/50043-0  0.88
2005 Kirby TW, DeRose EF, Beard WA, Wilson SH, London RE. A thymine isostere in the templating position disrupts assembly of the closed DNA polymerase beta ternary complex. Biochemistry. 44: 15230-7. PMID 16285726 DOI: 10.1021/bi0511742  0.88
2005 Beard WA, Wilson SH. Syn-full behavior by T7 DNA polymerase Structure. 13: 1580-1582. PMID 16271879 DOI: 10.1016/j.str.2005.10.003  0.88
2005 Wilson SH, Suk WA. Framework for environmental exposure research: The disease-first approach Molecular Interventions. 5: 262-267. PMID 16249520 DOI: 10.1124/mi.5.5.1  0.88
2005 Arora K, Beard WA, Wilson SH, Schlick T. Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity. Biochemistry. 44: 13328-41. PMID 16201758 DOI: 10.1021/bi0507682  0.88
2005 Prasad R, Batra VK, Yang XP, Krahn JM, Pedersen LC, Beard WA, Wilson SH. Structural insight into the DNA polymerase beta deoxyribose phosphate lyase mechanism. Dna Repair. 4: 1347-57. PMID 16172026 DOI: 10.1016/j.dnarep.2005.08.009  0.88
2005 Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. Structure (London, England : 1993). 13: 1225-33. PMID 16084394 DOI: 10.1016/j.str.2005.05.010  0.88
2005 Weis BK, Balshaw D, Barr JR, Brown D, Ellisman M, Lioy P, Omenn G, Potter JD, Smith MT, Sohn L, Suk WA, Sumner S, Swenberg J, Walt DR, Watkins S, ... ... Wilson SH, et al. Personalized exposure assessment: promising approaches for human environmental health research. Environmental Health Perspectives. 113: 840-8. PMID 16002370 DOI: 10.1289/ehp.7651  0.88
2005 Horton JK, Stefanick DF, Wilson SH. Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death Dna Repair. 4: 1111-1120. PMID 16002346 DOI: 10.1016/j.dnarep.2005.05.011  0.88
2005 Poltoratsky V, Horton JK, Prasad R, Wilson SH. REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. Dna Repair. 4: 1182-8. PMID 15950550 DOI: 10.1016/j.dnarep.2005.05.002  0.36
2005 Braithwaite EK, Prasad R, Shock DD, Hou EW, Beard WA, Wilson SH. DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. The Journal of Biological Chemistry. 280: 18469-75. PMID 15749700 DOI: 10.1074/jbc.M411864200  0.88
2005 Beard BC, Stevenson JJ, Wilson SH, Smerdon MJ. Base excision repair in nucleosomes lacking histone tails. Dna Repair. 4: 203-9. PMID 15590328 DOI: 10.1016/j.dnarep.2004.09.011  0.88
2005 Liu Y, Beard WA, Shock DD, Prasad R, Hou EW, Wilson SH. DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. The Journal of Biological Chemistry. 280: 3665-74. PMID 15561706 DOI: 10.1074/jbc.M412922200  0.88
2004 Krahn JM, Beard WA, Wilson SH. Structural insights into DNA polymerase β deterrents for misincorporation support an induced-fit mechanism for fidelity Structure. 12: 1823-1832. PMID 15458631 DOI: 10.1016/j.str.2004.08.001  0.88
2004 Wiederhold L, Leppard JB, Kedar P, Karimi-Busheri F, Rasouli-Nia A, Weinfeld M, Tomkinson AE, Izumi T, Prasad R, Wilson SH, Mitra S, Hazra TK. AP endonuclease-independent DNA base excision repair in human cells. Molecular Cell. 15: 209-20. PMID 15260972 DOI: 10.1016/j.molcel.2004.06.003  0.36
2004 Hu HY, Horton JK, Gryk MR, Prasad R, Naron JM, Sun DA, Hecht SM, Wilson SH, Mullen GP. Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. The Journal of Biological Chemistry. 279: 39736-44. PMID 15258144 DOI: 10.1074/jbc.M402842200  0.88
2004 Bose-Basu B, DeRose EF, Kirby TW, Mueller GA, Beard WA, Wilson SH, London RE. Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase beta. Biochemistry. 43: 8911-22. PMID 15248749 DOI: 10.1021/bi049641n  0.88
2004 Yang L, Arora K, Beard WA, Wilson SH, Schlick T. Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly. Journal of the American Chemical Society. 126: 8441-53. PMID 15238001 DOI: 10.1021/ja049412o  0.88
2004 Wilson SH, Olden K. The environmental genome project. Phase I and beyond Molecular Interventions. 4: 147-156. PMID 15210868 DOI: 10.1124/MI.4.3.4  0.88
2004 Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/JCI20926  0.88
2004 Yang L, Beard WA, Wilson SH, Broyde S, Schlick T. Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses. Biophysical Journal. 86: 3392-408. PMID 15189842 DOI: 10.1529/biophysj.103.036012  0.88
2004 Beard WA, Shock DD, Wilson SH. Influence of DNA structure on DNA polymerase β active site function. Extension of mutagenic DNA intermediates Journal of Biological Chemistry. 279: 31921-31929. PMID 15145936 DOI: 10.1074/jbc.M404016200  0.88
2004 Cistulli C, Lavrik OI, Prasad R, Hou E, Wilson SH. AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. Dna Repair. 3: 581-91. PMID 15135726 DOI: 10.1016/j.dnarep.2003.09.012  0.36
2004 Poltoratsky VP, Wilson SH, Kunkel TA, Pavlov YI. Recombinogenic phenotype of human activation-induced cytosine deaminase. Journal of Immunology (Baltimore, Md. : 1950). 172: 4308-13. PMID 15034045  0.88
2004 Hou EW, Prasad R, Beard WA, Wilson SH. High-level expression and purification of untagged and histidine-tagged HIV-1 reverse transcriptase. Protein Expression and Purification. 34: 75-86. PMID 14766302 DOI: 10.1016/j.pep.2003.10.018  0.88
2003 Chyan YJ, Rawson TY, Wilson SH. Cloning and characterization of a novel member of the human ATF/CREB family: ATF2 deletion, a potential regulator of the human DNA polymerase β promoter Gene. 312: 117-124. PMID 12909347 DOI: 10.1016/S0378-1119(03)00607-3  0.88
2003 Sobol RW, Kartalou M, Almeida KH, Joyce DF, Engelward BP, Horton JK, Prasad R, Samson LD, Wilson SH. Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. The Journal of Biological Chemistry. 278: 39951-9. PMID 12882965 DOI: 10.1074/jbc.M306592200  0.36
2003 Beard BC, Wilson SH, Smerdon MJ. Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 7465-70. PMID 12799467 DOI: 10.1073/pnas.1330328100  0.88
2003 Prasad R, Bebenek K, Hou E, Shock DD, Beard WA, Woodgate R, Kunkel TA, Wilson SH. Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. The Journal of Biological Chemistry. 278: 29649-54. PMID 12777390 DOI: 10.1074/jbc.M305399200  0.88
2003 Beard WA, Wilson SH. Structural insights into the origins of DNA polymerase fidelity Structure. 11: 489-496. PMID 12737815 DOI: 10.1016/S0969-2126(03)00051-0  0.88
2003 Friedberg EC, Hanaoka F, Tanaka K, Wilson SH, Yasui A, Sugasawa K, Matsunaga T, Madura K, Sweder K, Van Houten B, Cooper P, Shiomi T, Grollman A, Nakabeppu Y, Wallace S, et al. Report on the First US-Japan DNA Repair Meeting Sendai, Japan, October 27-31, 2002 Dna Repair. 2: 639-652. PMID 12713820 DOI: 10.1016/S1568-7864(03)00038-7  0.88
2003 Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH. Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Dna Repair. 2: 609-22. PMID 12713817 DOI: 10.1016/S1568-7864(03)00026-0  0.88
2003 He F, Yang XP, Srivastava DK, Wilson SH. DNA polymerase β gene expression: The promoter activator CREB-1 is upregulated in chinese hamster ovary cells by DNA alkylating agent-induced stress Biological Chemistry. 384: 19-23. PMID 12674496 DOI: 10.1515/BC.2003.003  0.88
2003 Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA. The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. The Journal of Biological Chemistry. 278: 22686-95. PMID 12665521 DOI: 10.1074/jbc.M213103200  0.88
2003 Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH. Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. Dna Repair. 2: 27-48. PMID 12509266 DOI: 10.1016/S1568-7864(02)00184-2  0.88
2003 Kim SJ, Beard WA, Harvey J, Shock DD, Knutson JR, Wilson SH. Rapid segmental and subdomain motions of DNA polymerase beta. The Journal of Biological Chemistry. 278: 5072-81. PMID 12458221 DOI: 10.1074/jbc.M208472200  0.88
2002 Horton JK, Baker A, Berg BJ, Sobol RW, Wilson SH. Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. Dna Repair. 1: 317-33. PMID 12509250 DOI: 10.1016/S1568-7864(02)00008-3  0.88
2002 Yang L, Beard W, Wilson S, Roux B, Broyde S, Schlick T. Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus. Journal of Molecular Biology. 321: 459-78. PMID 12162959 DOI: 10.1016/S0022-2836(02)00617-4  0.88
2002 Lavrik OI, Kolpashchikov DM, Prasad R, Sobol RW, Wilson SH. Binary system for selective photoaffinity labeling of base excision repair DNA polymerases. Nucleic Acids Research. 30: e73. PMID 12136121  0.88
2002 Kedar PS, Kim SJ, Robertson A, Hou E, Prasad R, Horton JK, Wilson SH. Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen. The Journal of Biological Chemistry. 277: 31115-23. PMID 12063248 DOI: 10.1074/jbc.M201497200  0.36
2002 Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/pnas.092662499  0.88
2002 Yang L, Beard WA, Wilson SH, Broyde S, Schlick T. Polymerase beta simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se. Journal of Molecular Biology. 317: 651-71. PMID 11955015 DOI: 10.1006/jmbi.2002.5450  0.88
2001 Chen KH, Srivastava DK, Wilson SH. Relationship between base excision repair capacity and DNA alkylating agent sensitivity in mouse monocytes Mutation Research - Dna Repair. 487: 121-126. PMID 11738938 DOI: 10.1016/S0921-8777(01)00110-0  0.88
2001 Beard WA, Wilson SH. DNA polymerases lose their grip Nature Structural Biology. 8: 915-917. PMID 11685231 DOI: 10.1038/nsb1101-915  0.88
2001 Beard WA, Wilson SH. DNA lesion bypass polymerases open up Structure. 9: 759-764. PMID 11566124 DOI: 10.1016/S0969-2126(01)00646-3  0.88
2001 Sobol RW, Wilson SH. Mammalian DNA β-polymerase in base excision repair of alkylation damage Progress in Nucleic Acid Research and Molecular Biology. 68: 57-74. PMID 11554313  0.88
2001 Belova GI, Prasad R, Kozyavkin SA, Lake JA, Wilson SH, Slesarev AI. A type IB topoisomerase with DNA repair activities Proceedings of the National Academy of Sciences of the United States of America. 98: 6015-6020. PMID 11353838 DOI: 10.1073/pnas.111040498  0.88
2001 Lavrik OI, Prasad R, Sobol RW, Horton JK, Ackerman EJ, Wilson SH. Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. The Journal of Biological Chemistry. 276: 25541-8. PMID 11340072 DOI: 10.1074/jbc.M102125200  0.88
2001 Bebenek K, Tissier A, Frank EG, McDonald JP, Prasad R, Wilson SH, Woodgate R, Kunkel TA. 5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. Science (New York, N.Y.). 291: 2156-9. PMID 11251121 DOI: 10.1126/science.1058386  0.36
2001 Zhou J, Ahn J, Wilson SH, Prives C. A role for p53 in base excision repair Embo Journal. 20: 914-923. PMID 11179235 DOI: 10.1093/emboj/20.4.914  0.88
2001 Vande Berg BJ, Beard WA, Wilson SH. DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase β. Implication for the identity of the rate-limiting conformational change Journal of Biological Chemistry. 276: 3408-3416. PMID 11024043 DOI: 10.1074/jbc.M002884200  0.88
2000 Wilson SH, Sobol RW, Beard WA, Horton JK, Prasad R, Vande Berg BJ. DNA polymerase beta and mammalian base excision repair. Cold Spring Harbor Symposia On Quantitative Biology. 65: 143-55. PMID 12760029 DOI: 10.1101/sqb.2000.65.143  0.88
2000 Narayan S, Wilson SH. Kinetic analysis of Sp1-mediated transcriptional activation of the human DNA polymerase β promoter Oncogene. 19: 4729-4735. PMID 11032023 DOI: 10.1038/sj.onc.1203823  0.88
2000 Beard WA, Wilson SH. Structural design of a eukaryotic DNA repair polymerase: DNA polymerase β Mutation Research - Dna Repair. 460: 231-244. PMID 10946231 DOI: 10.1016/S0921-8777(00)00029-X  0.88
2000 Sobol RW, Prasad R, Evenski A, Baker A, Yang XP, Horton JK, Wilson SH. The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity. Nature. 405: 807-10. PMID 10866204 DOI: 10.1038/35015598  0.88
2000 Deterding LJ, Prasad R, Mullen GP, Wilson SH, Tomer KB. Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase β by mass spectrometry Journal of Biological Chemistry. 275: 10463-10471. PMID 10744736 DOI: 10.1074/jbc.275.14.10463  0.88
2000 Wilson SH, Kunkel TA. Passing the baton in base excision repair Nature Structural Biology. 7: 176-178. PMID 10700268 DOI: 10.1038/73260  0.88
2000 Narayan S, Wilson SH. Kinetic analysis of Sp1-mediated transcriptional activation of a TATA-containing promoter. Biochemistry. 39: 818-23. PMID 10651648 DOI: 10.1021/bi9912701  0.88
2000 Horton JK, Prasad R, Hou E, Wilson SH. Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair. The Journal of Biological Chemistry. 275: 2211-8. PMID 10636928 DOI: 10.1074/jbc.275.3.2211  0.36
1999 Lewis DA, Bebenek K, Beard WA, Wilson SH, Kunkel TA. Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 274: 32924-30. PMID 10551858 DOI: 10.1074/jbc.274.46.32924  0.88
1999 Powell MD, Beard WA, Bebenek K, Howard KJ, Le Grice SF, Darden TA, Kunkel TA, Wilson SH, Levin JG. Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer. The Journal of Biological Chemistry. 274: 19885-93. PMID 10391934 DOI: 10.1074/jbc.274.28.19885  0.88
1998 Beard WA, Bebenek K, Darden TA, Li L, Prasad R, Kunkel TA, Wilson SH. Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions. The Journal of Biological Chemistry. 273: 30435-42. PMID 9804810 DOI: 10.1074/jbc.273.46.30435  0.88
1998 Dimitriadis EK, Prasad R, Vaske MK, Chen L, Tomkinson AE, Lewis MS, Wilson SH. Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta. The Journal of Biological Chemistry. 273: 20540-50. PMID 9685411 DOI: 10.1074/jbc.273.32.20540  0.36
1998 Wilson SH. Mammalian base excision repair and DNA polymerase beta Mutation Research - Dna Repair. 407: 203-215. PMID 9653447 DOI: 10.1016/S0921-8777(98)00002-0  0.88
1998 Fortini P, Pascucci B, Parlanti E, Sobol RW, Wilson SH, Dogliotti E. Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells Biochemistry. 37: 3575-3580. PMID 9530283 DOI: 10.1021/bi972999h  0.88
1998 Chen KH, Yakes FM, Srivastava DK, Singhal RK, Sobol RW, Horton JK, Van Houten B, Wilson SH. Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Research. 26: 2001-7. PMID 9518496 DOI: 10.1093/nar/26.8.2001  0.88
1998 Beard WA, Wilson SH. Structural insights into DNA polymerase β fidelity: Hold tight if you want it right Chemistry and Biology. 5. PMID 9479474 DOI: 10.1016/S1074-5521(98)90081-3  0.88
1998 Kunkel TA, Wilson SH. DNA polymerases on the move Nature Structural Biology. 5: 95-99. PMID 9461069 DOI: 10.1038/nsb0298-95  0.88
1998 Singh SB, Beard WA, Hingerty BE, Wilson SH, Broyde S. Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction. Biochemistry. 37: 878-84. PMID 9454577 DOI: 10.1021/bi9720639  0.88
1998 Biade S, Sobol RW, Wilson SH, Matsumoto Y. Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA Journal of Biological Chemistry. 273: 898-902. PMID 9422747 DOI: 10.1074/jbc.273.2.898  0.88
1998 Lavrik OI, Nasheuer HP, Weisshart K, Wold MS, Prasad R, Beard WA, Wilson SH, Favre A. Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases. Nucleic Acids Research. 26: 602-7. PMID 9421522 DOI: 10.1093/nar/26.2.602  0.88
1997 Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 36: 11205-15. PMID 9287163 DOI: 10.1021/bi9703812  0.88
1997 Bebenek K, Beard WA, Darden TA, Li L, Prasad R, Luton BA, Gorenstein DG, Wilson SH, Kunkel TA. A minor groove binding track in reverse transcriptase. Nature Structural Biology. 4: 194-7. PMID 9164459 DOI: 10.1038/nsb0397-194  0.88
1997 Mullen GP, Wilson SH. DNA polymerase β in abasic site repair: A structurally conserved helix- hairpin-helix motif in lesion detection by base excision repair enzymes Biochemistry. 36: 4713-4717. PMID 9125491 DOI: 10.1021/bi962363a  0.88
1996 Kunkel TA, Wilson SH. Push and pull of base flipping Nature. 384: 25-26. PMID 8900270 DOI: 10.1038/384025a0  0.88
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta. Biochemistry. 35: 12762-77. PMID 8841119 DOI: 10.1021/bi9529566  0.88
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry. 35: 12742-61. PMID 8841118 DOI: 10.1021/bi952955d  0.88
1996 Lavrik OI, Prasad R, Beard WA, Safronov IV, Dobrikov MI, Srivastava DK, Shishkin GV, Wood TG, Wilson SH. dNTP binding to HIV-1 reverse transcriptase and mammalian DNA polymerase beta as revealed by affinity labeling with a photoreactive dNTP analog. The Journal of Biological Chemistry. 271: 21891-7. PMID 8702991 DOI: 10.1074/JBC.271.36.21891  0.88
1996 Reha-Krantz LJ, Nonay RL, Day RS, Wilson SH. Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. The Journal of Biological Chemistry. 271: 20088-95. PMID 8702729 DOI: 10.1074/jbc.271.33.20088  0.88
1996 Narayan S, He F, Wilson SH. Activation of the human DNA polymerase β promoter by a DNA-alkylating agent through induced phosphorylation of cAMP response element-binding protein-1 Journal of Biological Chemistry. 271: 18508-18513. PMID 8702497 DOI: 10.1074/jbc.271.31.18508  0.88
1996 Piersen CE, Prasad R, Wilson SH, Lloyd RS. Evidence for an imino intermediate in the DNA polymerase β deoxyribose phosphate excision reaction Journal of Biological Chemistry. 271: 17811-17815. PMID 8663612 DOI: 10.1074/jbc.271.30.17811  0.88
1996 Oda N, Saxena JK, Jenkins TM, Prasad R, Wilson SH, Ackerman EJ. DNA polymerases alpha and beta are required for DNA repair in an efficient nuclear extract from Xenopus oocytes. The Journal of Biological Chemistry. 271: 13816-20. PMID 8662731 DOI: 10.1074/jbc.271.23.13816  0.88
1996 Beard WA, Minnick DT, Wade CL, Prasad R, Won RL, Kumar A, Kunkel TA, Wilson SH. Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis. The Journal of Biological Chemistry. 271: 12213-20. PMID 8647817  0.88
1996 Beard WA, Osheroff WP, Prasad R, Sawaya MR, Jaju M, Wood TG, Kraut J, Kunkel TA, Wilson SH. Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta. The Journal of Biological Chemistry. 271: 12141-4. PMID 8647805 DOI: 10.1074/jbc.271.21.12141  0.88
1996 He F, Narayan S, Wilson SH. Purification and characterization of a DNA polymerase β promoter initiator element-binding transcription factor from bovine testis Biochemistry. 35: 1775-1782. PMID 8639658 DOI: 10.1021/bi9525987  0.88
1996 Sobol RW, Horton JK, Kühn R, Gu H, Singhal RK, Prasad R, Rajewsky K, Wilson SH. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature. 379: 183-6. PMID 8538772 DOI: 10.1038/379183a0  0.88
1995 Beard WA, Wilson SH. Purification and domain-mapping of mammalian DNA polymerase β Methods in Enzymology. 262: 98-107. PMID 8594388 DOI: 10.1016/0076-6879(95)62013-3  0.88
1995 Singhal RK, Prasad R, Wilson SH. DNA polymerase β conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract Journal of Biological Chemistry. 270: 949-957. PMID 7822335 DOI: 10.1074/jbc.270.2.949  0.88
1995 Srivastava DK, Rawson TY, Showalter SD, Wilson SH. Phorbol ester abrogates up-regulation of DNA polymerase β by DNA-alkylating agents in Chinese hamster ovary cells Journal of Biological Chemistry. 270: 16402-16408. PMID 7608211 DOI: 10.1074/JBC.270.27.16402  0.88
1995 Bebenek K, Beard WA, Casas-Finet JR, Kim HR, Darden TA, Wilson SH, Kunkel TA. Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. The Journal of Biological Chemistry. 270: 19516-23. PMID 7543900 DOI: 10.1074/jbc.270.33.19516  0.88
1995 Jaju M, Beard WA, Wilson SH. Human immunodeficiency virus type 1 reverse transcriptase. 3'- azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer Journal of Biological Chemistry. 270: 9740-9747. PMID 7537269 DOI: 10.1074/jbc.270.17.9740  0.88
1994 Beard WA, Wilson SH. Site-directed mutagenesis of HIV reverse transcriptase to probe enzyme processivity and drug binding Current Opinion in Biotechnology. 5: 414-421. PMID 7520785 DOI: 10.1016/0958-1669(94)90051-5  0.88
1994 Sawaya MR, Pelletier H, Kumar A, Wilson SH, Kraut J. Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science (New York, N.Y.). 264: 1930-5. PMID 7516581 DOI: 10.1126/SCIENCE.7516581  0.88
1994 Delahunty MD, Wilson SH, Karpel RL. Studies on primer binding of HIV-1 reverse transcriptase using a fluorescent probe Journal of Molecular Biology. 236: 469-479. PMID 7508989 DOI: 10.1006/jmbi.1994.1158  0.88
1993 Chen KH, Widen SG, Wilson SH, Huang KP. Identification of a nuclear protein binding element within the rat brain protein kinase C γ promoter that is related to the developmental control of this gene Febs Letters. 325: 210-214. PMID 8319805 DOI: 10.1016/0014-5793(93)81075-B  0.88
1993 Sobol RW, Fisher WL, Reichenbach NL, Kumar A, Beard WA, Wilson SH, Charubala R, Pfleiderer W, Suhadolnik RJ. HIV-1 reverse transcriptase: inhibition by 2',5'-oligoadenylates. Biochemistry. 32: 12112-8. PMID 7692966  0.88
1993 Kawa S, Kumar A, Smith JS, Becerra SP, Beard WA, Wilson SH, Thompson EB. Expression and purification of the HIV-1 reverse transcriptase using the baculovirus expression vector system. Protein Expression and Purification. 4: 298-303. PMID 7690627 DOI: 10.1006/prep.1993.1038  0.88
1993 Becerra SP, Kumar A, Wilson SH. Expression of Polypeptides of Human Immunodeficiency Virus-1 Reverse Transcriptase in Escherichia coli Protein Expression and Purification. 4: 187-199. DOI: 10.1006/prep.1993.1025  0.88
1992 Englander EW, Wilson SH. DNA damage response of cloned DNA β-polymerase promoter is blocked in mutant cell lines deficient in protein kinase A Nucleic Acids Research. 20: 5527-5531. PMID 1454516 DOI: 10.1093/nar/20.21.5527  0.88
1992 Jenkins TM, Saxena JK, Kumar A, Wilson SH, Ackerman EJ. DNA polymerase beta and DNA synthesis in Xenopus oocytes and in a nuclear extract. Science (New York, N.Y.). 258: 475-8. PMID 1411545 DOI: 10.1126/SCIENCE.1411545  0.88
1992 Casas-Finet J, Wilson SH, Karpel RL. Selective photochemical modification by trichloroethanol of tryptophan residues in proteins with a high tyrosine-to-tryptophan ratio Analytical Biochemistry. 205: 27-35. PMID 1332536 DOI: 10.1016/0003-2697(92)90574-Q  0.88
1992 Englander EW, Wilson SH. The cloned promoter of the human DNA β-polymerase gene contains a cAMP response element functional in HeLa cells Dna and Cell Biology. 11: 61-69. PMID 1310859 DOI: 10.1089/DNA.1992.11.61  0.88
1992 Abbotts J, Wilson SH. Inhibitors of HIV-1 reverse transcriptase and fidelity of in vitro DNA replication Journal of Enzyme Inhibition and Medicinal Chemistry. 6: 35-46. PMID 1285301 DOI: 10.3109/14756369209041354  0.88
1991 Englander EW, Widen SG, Wilson SH. Mammalian β-polymerase promoter: Phosphorylation of ATF/CRE-binding protein and regulation of DNA binding Nucleic Acids Research. 19: 3369-3375. PMID 1829517 DOI: 10.1093/nar/19.12.3369  0.88
1991 Widen SG, Wilson SH. Mammalian β-polyrnerase promoter: Large-scale purification and properties of ATF/CREB palindrome binding protein from bovine testes Biochemistry. 30: 6296-6305. PMID 1829381 DOI: 10.1021/BI00239A031  0.88
1991 Sobol RW, Suhadolnik RJ, Kumar A, Lee BJ, Hatfield DL, Wilson SH. Localization of a polynucleotide binding region in the HIV-1 reverse transcriptase: Implications for primer binding Biochemistry. 30: 10623-10631. PMID 1718424  0.88
1991 Casas-Finet JR, Karpel RL, Maki AH, Kumar A, Wilson SH. Physical studies of tyrosine and tryptophan residues in mammalian A1 heterogeneous nuclear ribonucleoprotein. Support for a segmented structure. Journal of Molecular Biology. 221: 693-709. PMID 1656054 DOI: 10.1016/0022-2836(91)80081-5  0.88
1990 Englander EW, Wilson SH. Protein binding elements in the human β-polymerase promoter Nucleic Acids Research. 18: 919-928. PMID 2315044 DOI: 10.1093/nar/18.4.919  0.88
1990 Kumar A, Abbotts J, Karawya EM, Wilson SH. Identification and properties of the catalytic domain of mammalian DNA polymerase β Biochemistry. 29: 7156-7159. PMID 2207097 DOI: 10.1021/bi00483a002  0.88
1990 Kedar PS, Lowy DR, Widen SG, Wilson SH. Transfected human β-polymerase promoter contains a ras-responsive element Molecular and Cellular Biology. 10: 3852-3856. PMID 2192267 DOI: 10.1128/MCB.10.7.3852  0.88
1990 Kay BK, Sawhney RK, Wilson SH. Potential for two isoforms of the A1 ribonucleoprotein in Xenopus laevis Proceedings of the National Academy of Sciences of the United States of America. 87: 1367-1371. PMID 2137612 DOI: 10.1073/PNAS.87.4.1367  0.88
1990 McBride OW, Kozak CA, Wilson SH. Mapping of the gene for DNA polymerase β to mouse chromosome 8 Cytogenetic and Genome Research. 53: 108-111. PMID 1973375 DOI: 10.1159/000132906  0.88
1990 Kumar A, Wilson SH. Studies of the strand-annealing activity of mammalian hnRNP complex protein A1 Biochemistry. 29: 10717-10722. PMID 1703006 DOI: 10.1021/bi00500a001  0.88
1990 Zmudzka BZ, Wilson SH. Deregulation of DNA polymerase β by sense and antisense RNA expression in mouse 3T3 cells alters cell growth Somatic Cell and Molecular Genetics. 16: 311-320. PMID 1699288 DOI: 10.1007/BF01232459  0.88
1989 Basu A, Kedar P, Wilson SH, Modak MJ. Active-site modification of mammalian DNA polymerase β with pyridoxal 5′-phosphate: Mechanism of inhibition and identification of lysine 71 in the deoxynucleoside triphosphate binding pocket Biochemistry. 28: 6305-6309. PMID 2506925 DOI: 10.1021/bi00441a023  0.88
1989 Majumdar C, Stein CA, Cohen JS, Broder S, Wilson SH. Stepwise mechanism of HIV reverse transcriptase: Primer function of phosphorothioate oligodeoxynucleotide Biochemistry. 28: 1340-1346. PMID 2469468 DOI: 10.1021/bi00429a060  0.88
1988 Abbotts J, SenGupta DN, Zmudzka B, Widen SG, Notario V, Wilson SH. Expression of human DNA polymerase β in Escherichia coli and characterization of the recombinant enzyme Biochemistry. 27: 901-909. PMID 3284575  0.88
1988 Jensen L, Kuff EL, Wilson SH, Steinberg AD, Klinman DM. Antibodies from patients and mice with autoimmune diseases react with recombinant hnRNP core protein A1 Journal of Autoimmunity. 1: 73-83. PMID 3267110 DOI: 10.1016/0896-8411(88)90078-9  0.88
1988 Zmudzka BZ, Fomace A, Collins J, Wilson SH. Characterization of DNA polymerase β mRNA: Cell-cycle and growth response in cultured human cells Nucleic Acids Research. 16: 9587-9596. PMID 2460824 DOI: 10.1093/nar/16.20.9587  0.88
1987 McBride OW, Zmudzka BZ, Wilson SH. Chromosomal location of the human gene for DNA polymerase β Proceedings of the National Academy of Sciences of the United States of America. 84: 503-507. PMID 3467369 DOI: 10.1073/pnas.84.2.503  0.88
1987 Anderson RS, Lawrence CB, Wilson SH, Beattie KL. Genetic relatedness of human DNA polymerase β and terminal deoxynucleotidyltransferase Gene. 60: 163-173. PMID 3443300 DOI: 10.1016/0378-1119(87)90224-1  0.88
1987 Cobianchi F, Wilson SH. Enzymes for modifying and labeling DNA and RNA Methods in Enzymology. 152: 94-110. PMID 2443813 DOI: 10.1016/0076-6879(87)52013-4  0.88
1986 Sharief FS, Wilson SH, Li SSL. Identification of the mouse low-salt-eluting single-stranded DNA-binding protein as a mammalian lactate dehydrogenase-A isoenzyme Biochemical Journal. 233: 913-916. PMID 3707535 DOI: 10.1042/bj2330913  0.88
1985 Mitchell JB, Karawya E, Kinsella TJ, Wilson SH. Measurement of DNA polymerase β in skin fibroblast cell lines from patients with ataxia telangiectasia Mutation Research Dna Repair Reports. 146: 295-300. PMID 4058446 DOI: 10.1016/0167-8817(85)90071-9  0.88
1985 Planck SR, Wilson SH. Native species of helix destabilizing protein-1 in mouse myeloma identified by antibody probing of Western blots Biochemical and Biophysical Research Communications. 131: 362-369. PMID 2994656 DOI: 10.1016/0006-291X(85)91811-X  0.88
1984 Detera-Wadleigh S, Karawya E, Wilson SH. Synthesis of DNA polymerase by in vitro translation of calf RNA Biochemical and Biophysical Research Communications. 122: 420-427. PMID 6743342 DOI: 10.1016/0006-291X(84)90492-3  0.88
1984 Becerra SP, Wilson SH. Properties of a novel oligonucleotide-releasing bidirectional DNA exonuclease from mouse myeloma Biochemistry. 23: 908-914. PMID 6538798 DOI: 10.1021/bi00300a018  0.88
1984 Hazra AK, Detera-Wadleigh S, Wilson SH. Site-specific modification of Escherichia coli DNA polymerase I large fragment with pyridoxal 5′-phosphate Biochemistry. 23: 2073-2078. PMID 6426512 DOI: 10.1021/bi00304a030  0.88
1984 Detera-Wadleigh S, Karawya E, Wilson SH. Synthesis of catalytically active polymerase alpha by in vitro translation of calf RNA Advances in Experimental Medicine and Biology. 179: 343-353. PMID 6084407 DOI: 10.1007/978-1-4684-8730-5_36  0.88
1983 Becerra SP, Detera SD, Wilson SH. Anomalous electrophoretic migration of oligodeoxynucleotides with terminal OH groups: Applications for DNA exonuclease characterization Analytical Biochemistry. 129: 200-206. PMID 6859523 DOI: 10.1016/0003-2697(83)90069-6  0.88
1983 Karawya E, Swack JA, Wilson SH. Improved conditions for activity gel analysis of DNA polymerase catalytic polypeptides Analytical Biochemistry. 135: 318-325. PMID 6660508 DOI: 10.1016/0003-2697(83)90689-9  0.88
1983 Tanabe K, Karawya E, Fewell JW, Kuff EL, Wilson SH. DNA polymerase and simian virus 40 infection of resting monkey cells: Induction of aphidicolin resistant α-polymerase Nucleic Acids Research. 11: 8253-8268. DOI: 10.1093/nar/11.23.8253  0.88
1982 Albert W, Grummt F, Hübscher U, Wilson SH. Structural homology among calf thymus α-polymerase polypeptides Nucleic Acids Research. 10: 935-946. PMID 7063421 DOI: 10.1093/nar/10.3.935  0.88
1980 Planck SR, Tanabe K, Wilson SH. Distinction between mouse DNA polymerases α and β by tryptic peptide mapping Nucleic Acids Research. 8: 2771-2782. PMID 7433094 DOI: 10.1093/nar/8.12.2771  0.88
1979 Minna JD, Marshall TH, Brown SH, Burk RD, Lemons RS, Wilson SH. Regulation of expression of type C virion DNA polymerase (reverse transcriptase) in human x mouse and human x rat hybrid cells. Somatic Cell Genetics. 5: 991-1011. PMID 94700 DOI: 10.1007/BF01542656  0.88
1978 Pitha J, Wilson SH, Pitha PM. A vinyl polymer with purine residues deficient in base pairing inhibits murine leukemia virus replication Biochemical and Biophysical Research Communications. 81: 217-223. PMID 207272 DOI: 10.1016/0006-291X(78)91652-2  0.88
1976 Schrier BK, Wilson SH. On the measurement of tritium in DNA and its application to the assay of DNA polymerase activity Methods in Cell Biology. 105-120. PMID 1263849 DOI: 10.1016/S0091-679X(08)61799-9  0.88
1976 Matsukage A, Sivarajan M, Wilson SH. Studies on DNA α-polymerase of mouse myeloma: Partial purification and comparison of three molecular forms of the enzyme Biochemistry. 15: 5305-5314. PMID 999808 DOI: 10.1021/bi00669a017  0.88
1975 Matsukage A, Bohn EW, Wilson SH. Differential sensitivity of low molecular weight DNA polymerase to sulfhydryl-blocking reagents Bba Section Nucleic Acids and Protein Synthesis. 383: 338-343. PMID 1167793 DOI: 10.1016/0005-2787(75)90062-3  0.88
1975 Matsukage A, Bohn EW, Wilson SH. On the DNA polymerase III of mouse myeloma: Partial purification and characterization Biochemistry. 14: 1006-1020. PMID 235942 DOI: 10.1021/bi00676a020  0.88
1974 Matsukage A, Bohn EW, Wilson SH. Multiple forms of DNA polymerase in mouse myeloma Proceedings of the National Academy of Sciences of the United States of America. 71: 578-582. PMID 4521824 DOI: 10.1073/pnas.71.2.578  0.88
1974 Stromberg K, Wilson SH. Structural studies of avian myeloblastosis virus. Selective release of ribonucleoprotein polypeptides from the core component and partial purification of the DNA polymerase Bba Section Nucleic Acids and Protein Synthesis. 361: 53-58. PMID 4376423 DOI: 10.1016/0005-2787(74)90208-1  0.88
1974 Bohn EW, Matsukage A, Wilson SH. Stimulation of DNA polymerase activity by the combination of p-hydroxymercuribenzoate and dithiothreitol Biochemical and Biophysical Research Communications. 59: 243-251. PMID 4366959 DOI: 10.1016/S0006-291X(74)80199-3  0.88
1974 Schrier BK, Wilson SH, Nirenberg M. Cultured cell systems and methods for neurobiology. Methods in Enzymology. 32: 765-88. PMID 4155470 DOI: 10.1016/0076-6879(74)32080-0  0.88
1973 Schrier BK, Wilson SH. Investigation of methods for measurement of radioactivity in tritiated DNA and applications to assays for DNA polymerase activity Analytical Biochemistry. 56: 196-207. PMID 4797195 DOI: 10.1016/0003-2697(73)90184-X  0.88
1973 Stromberg K, Gantt R, Wilson SH. Structural studies on avian myeloblastosis virus: Conditions for isolation and biochemical characteristics of the core component Bba - General Subjects. 304: 1-11. PMID 4349411 DOI: 10.1016/0304-4165(73)90109-8  0.88
1972 Hill HZ, Wilson SH, Hoagland MB. Patterns of albumin and general protein synthesis in rat liver as revealed by gel electrophoresis. Biochimica Et Biophysica Acta. 269: 477-84. PMID 5039545 DOI: 10.1016/0005-2787(72)90135-9  0.88
1972 Wilson SH, Kuff EL. A novel DNA polymerase activity found in association with intracisternal A-type particles Proceedings of the National Academy of Sciences of the United States of America. 69: 1531-1536. PMID 4504367 DOI: 10.1073/pnas.69.6.1531  0.88
1971 Wilson SH, Kronick MN. New assay technique for reactions that produce radioactive gases Analytical Biochemistry. 43: 460-467. PMID 5141091 DOI: 10.1016/0003-2697(71)90276-4  0.88
1970 Blume A, Gilbert F, Wilson S, Farber J, Rosenberg R, Nirenberg M. Regulation of acetylcholinesterase in neuroblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 67: 786-92. PMID 5289021 DOI: 10.1073/pnas.67.2.786  0.88
1969 Quincey RV, Wilson SH. The utilization of genes for ribosomal RNA, 5S RNA, and transfer RNA in liver cells of adult rats Proceedings of the National Academy of Sciences of the United States of America. 64: 981-988. PMID 5264152 DOI: 10.1073/pnas.64.3.981  0.88
1967 Wilson SH, Hoagland MB. Physiology of rat-liver polysomes. The stability of messenger ribonucleic acid and ribosomes. The Biochemical Journal. 103: 556-66. PMID 6032987 DOI: 10.1042/bj1030556  0.88
1967 Wilson SH, Hill HZ, Hoagland MB. Physiology of rat-liver polysomes. Protein synthesis by stable polysomes. The Biochemical Journal. 103: 567-72. PMID 4962085 DOI: 10.1042/bj1030567  0.88
1965 Wilson SH, Hoagland MB. Studies on the physiology of rat liver polyribosomes: quantition and intracellular distribution of ribosomes. Proceedings of the National Academy of Sciences of the United States of America. 54: 600-7. PMID 5217447 DOI: 10.1073/pnas.54.2.600  0.88
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