| Year |
Citation |
Score |
| 2017 |
Gustin JP, Miller J, Farag M, Rosen DM, Thomas M, Scharpf RB, Lauring J. GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers. Oncotarget. 8: 103415-103427. PMID 29262572 DOI: 10.18632/oncotarget.21910 |
0.63 |
|
| 2013 |
Beaver JA, Gustin JP, Yi KH, Rajpurohit A, Thomas M, Gilbert SF, Rosen DM, Ho Park B, Lauring J. PIK3CA and AKT1 mutations have distinct effects on sensitivity to targeted pathway inhibitors in an isogenic luminal breast cancer model system. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5413-22. PMID 23888070 DOI: 10.1158/1078-0432.Ccr-13-0884 |
0.521 |
|
| 2013 |
Wang GM, Wong HY, Konishi H, Blair BG, Abukhdeir AM, Gustin JP, Rosen DM, Denmeade SR, Rasheed Z, Matsui W, Garay JP, Mohseni M, Higgins MJ, Cidado J, Jelovac D, et al. Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. Cancer Research. 73: 3248-61. PMID 23580570 DOI: 10.1158/0008-5472.Can-12-1578 |
0.74 |
|
| 2013 |
Yi KH, Axtmayer J, Gustin JP, Rajpurohit A, Lauring J. Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine. Oncotarget. 4: 29-34. PMID 23237847 DOI: 10.18632/oncotarget.755 |
0.597 |
|
| 2012 |
Garay JP, Karakas B, Abukhdeir AM, Cosgrove DP, Gustin JP, Higgins MJ, Konishi H, Konishi Y, Lauring J, Mohseni M, Wang GM, Jelovac D, Weeraratna A, Sherman Baust CA, Morin PJ, et al. The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation. Breast Cancer Research : Bcr. 14: R27. PMID 22321971 DOI: 10.1186/Bcr3112 |
0.775 |
|
| 2011 |
Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, et al. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 17773-8. PMID 21987798 DOI: 10.1073/Pnas.1110969108 |
0.786 |
|
| 2011 |
Higgins MJ, Beaver JA, Wong HY, Gustin JP, Lauring JD, Garay JP, Konishi H, Mohseni M, Wang GM, Cidado J, Jelovac D, Cosgrove DP, Tamaki A, Abukhdeir AM, Park BH. PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells. Cancer Biology & Therapy. 11: 358-67. PMID 21124076 DOI: 10.4161/Cbt.11.3.14227 |
0.794 |
|
| 2010 |
Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, et al. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations Oncogene. 29: 2337-2345. PMID 20101210 DOI: 10.1038/Onc.2009.516 |
0.811 |
|
| 2009 |
Higgins MJ, Abukhdeir AM, Gustin J, Vitolo MI, Bachman KE, Park BH. Preclinical study of lithium sensitivity in human breast PTEN knock out cell lines. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e14641. PMID 27964232 DOI: 10.1200/Jco.2009.27.15_Suppl.E14641 |
0.784 |
|
| 2009 |
Gustin JP, Karakas B, Weiss MB, Abukhdeir AM, Lauring J, Garay JP, Cosgrove D, Tamaki A, Konishi H, Konishi Y, Mohseni M, Wang G, Rosen DM, Denmeade SR, Higgins MJ, et al. Knockin of mutant PIK3CA activates multiple oncogenic pathways. Proceedings of the National Academy of Sciences of the United States of America. 106: 2835-40. PMID 19196980 DOI: 10.1073/Pnas.0813351106 |
0.82 |
|
| 2008 |
Gustin JP, Cosgrove DP, Park BH. The PIK3CA gene as a mutated target for cancer therapy. Current Cancer Drug Targets. 8: 733-40. PMID 19075596 DOI: 10.2174/156800908786733504 |
0.686 |
|
| 2008 |
Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, et al. Tamoxifen-stimulated growth of breast cancer due to p21 loss. Proceedings of the National Academy of Sciences of the United States of America. 105: 288-93. PMID 18162533 DOI: 10.1073/Pnas.0710887105 |
0.799 |
|
| 2008 |
Lauring J, Abukhdeir AM, Konishi H, Garay JP, Gustin JP, Wang Q, Arceci RJ, Matsui W, Park BH. The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity. Blood. 111: 856-64. PMID 17942756 DOI: 10.1182/Blood-2007-05-088674 |
0.769 |
|
| 2007 |
Konishi H, Lauring J, Garay JP, Karakas B, Abukhdeir AM, Gustin JP, Konishi Y, Park BH. A PCR-based high-throughput screen with multiround sample pooling: application to somatic cell gene targeting. Nature Protocols. 2: 2865-74. PMID 18007621 DOI: 10.1038/Nprot.2007.409 |
0.752 |
|
| 2007 |
Konishi H, Karakas B, Abukhdeir AM, Lauring J, Gustin JP, Garay JP, Konishi Y, Gallmeier E, Bachman KE, Park BH. Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation. Cancer Research. 67: 8460-7. PMID 17875684 DOI: 10.1158/0008-5472.Can-07-0108 |
0.803 |
|
| 2007 |
Karakas B, Weeraratna AT, Abukhdeir AM, Konishi H, Gustin JP, Vitolo MI, Bachman KE, Park BH. P21 gene knock down does not identify genetic effectors seen with gene knock out. Cancer Biology & Therapy. 6: 1025-30. PMID 17611398 DOI: 10.4161/Cbt.6.7.4202 |
0.586 |
|
| 2007 |
Lauring J, Abukhdeir AM, Konishi H, Garay JP, Gustin JP, Wang Q, Arceci RJ, Matsui W, Park BH. The MMSET Gene Contributes to the Growth, Adhesion, and Tumorigencitiy of t(4;14) Multiple Myeloma Cells. Blood. 110: 2636-2636. DOI: 10.1182/Blood.V110.11.2636.2636 |
0.772 |
|
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