| Year |
Citation |
Score |
| 2023 |
Villa N, Fraser CS. Human eukaryotic initiation factor 4G directly binds the 40S ribosomal subunit to promote efficient translation. Biorxiv : the Preprint Server For Biology. PMID 37808713 DOI: 10.1101/2023.09.29.560218 |
0.496 |
|
| 2023 |
O'Sullivan MH, Fraser CS. Monitoring RNA restructuring in a human cell-free extract reveals eIF4A-dependent and eIF4A-independent unwinding activity. The Journal of Biological Chemistry. 104936. PMID 37331603 DOI: 10.1016/j.jbc.2023.104936 |
0.377 |
|
| 2022 |
Lipo E, Asrat S, Huo W, Sol A, Fraser CS, Isberg RR. 5' Untranslated mRNA Regions Allow Bypass of Host Cell Translation Inhibition by Legionella pneumophila. Infection and Immunity. e0017922. PMID 36321832 DOI: 10.1128/iai.00179-22 |
0.311 |
|
| 2022 |
Izidoro MS, Sokabe M, Villa N, Merrick WC, Fraser CS. Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA. The Journal of Biological Chemistry. 102368. PMID 35963437 DOI: 10.1016/j.jbc.2022.102368 |
0.383 |
|
| 2022 |
Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J, Montabana E, Villa N, Shin BS, Dever TE, Fraser CS, Fernández IS, Puglisi JD. eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature. PMID 35732735 DOI: 10.1038/s41586-022-04858-z |
0.479 |
|
| 2020 |
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V. Structure of a human 48 translational initiation complex. Science (New York, N.Y.). 369: 1220-1227. PMID 32883864 DOI: 10.1126/Science.Aba4904 |
0.563 |
|
| 2020 |
Cunningham EB, Hajarizadeh B, Amin J, Hellard M, Bruneau J, Feld JJ, Cooper C, Powis J, Litwin AH, Marks P, Dalgard O, Conway B, Moriggia A, Stedman C, Read P, ... ... Fraser C, et al. Reinfection following successful direct-acting antiviral therapy for hepatitis C infection among people who inject drugs. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32166305 DOI: 10.1093/Cid/Ciaa253 |
0.328 |
|
| 2019 |
Howard CM, Bearss N, Subramaniyan B, Tilley A, Sridharan S, Villa N, Fraser CS, Raman D. The CXCR4-LASP1-eIF4F Axis Promotes Translation of Oncogenic Proteins in Triple-Negative Breast Cancer Cells. Frontiers in Oncology. 9: 284. PMID 31106142 DOI: 10.3389/Fonc.2019.00284 |
0.35 |
|
| 2018 |
Grebely J, Conway B, Cunningham EB, Fraser C, Moriggia A, Gane E, Stedman C, Cooper C, Castro E, Schmid P, Petoumenos K, Hajarizadeh B, Marks P, Erratt A, Dalgard O, et al. Paritaprevir, ritonavir, ombitasvir, and dasabuvir with and without ribavirin in people with HCV genotype 1 and recent injecting drug use or receiving opioid substitution therapy. The International Journal On Drug Policy. 62: 94-103. PMID 30384028 DOI: 10.1016/J.Drugpo.2018.10.004 |
0.307 |
|
| 2018 |
Avanzino BC, Jue H, Miller CM, Cheung E, Fuchs G, Fraser CS. Molecular mechanism of poliovirus Sabin vaccine strain attenuation. The Journal of Biological Chemistry. PMID 30126841 DOI: 10.1074/Jbc.Ra118.004913 |
0.494 |
|
| 2018 |
Sokabe M, Fraser CS. Toward a Kinetic Understanding of Eukaryotic Translation. Cold Spring Harbor Perspectives in Biology. PMID 29959192 DOI: 10.1101/Cshperspect.A032706 |
0.348 |
|
| 2018 |
Grebely J, Dalgard O, Conway B, Cunningham EB, Bruggmann P, Hajarizadeh B, Amin J, Bruneau J, Hellard M, Litwin AH, Marks P, Quiene S, Siriragavan S, Applegate TL, Swan T, ... ... Fraser C, et al. Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial. The Lancet. Gastroenterology & Hepatology. PMID 29310928 DOI: 10.1016/S2468-1253(17)30404-1 |
0.31 |
|
| 2018 |
Korostelev AA, Fraser CS. Decision letter: Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition Elife. DOI: 10.7554/Elife.39273.049 |
0.442 |
|
| 2017 |
Avanzino BC, Fuchs G, Fraser CS. Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation. Proceedings of the National Academy of Sciences of the United States of America. 114: 9611-9616. PMID 28827335 DOI: 10.1073/Pnas.1704390114 |
0.51 |
|
| 2017 |
Sokabe M, Fraser CS. A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome. Proceedings of the National Academy of Sciences of the United States of America. 114: 6304-6309. PMID 28559306 DOI: 10.1073/Pnas.1620426114 |
0.569 |
|
| 2016 |
Barbosa NM, Boldrin PE, Rossi D, Yamamoto PA, Watanabe TF, Serrão VH, Hershey JW, Fraser CS, Valentini SR, Zanelli CF. Mapping surface residues of eIF5A that are important for binding to the ribosome using alanine scanning mutagenesis. Amino Acids. 48: 2363-74. PMID 27388480 DOI: 10.1007/s00726-016-2279-z |
0.328 |
|
| 2016 |
Rossi D, Barbosa NM, Galvão FC, Boldrin PE, Hershey JW, Zanelli CF, Fraser CS, Valentini SR. Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome. Plos One. 11: e0154205. PMID 27115996 DOI: 10.1371/Journal.Pone.0154205 |
0.472 |
|
| 2015 |
García-García C, Frieda KL, Feoktistova K, Fraser CS, Block SM. RNA BIOCHEMISTRY. Factor-dependent processivity in human eIF4A DEAD-box helicase. Science (New York, N.Y.). 348: 1486-8. PMID 26113725 DOI: 10.1126/Science.Aaa5089 |
0.501 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/Elife.07314 |
0.368 |
|
| 2015 |
Fraser CS. Quantitative studies of mRNA recruitment to the eukaryotic ribosome. Biochimie. 114: 58-71. PMID 25742741 DOI: 10.1016/J.Biochi.2015.02.017 |
0.519 |
|
| 2014 |
Sokabe M, Fraser CS. Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex. The Journal of Biological Chemistry. 289: 31827-36. PMID 25246524 DOI: 10.1074/Jbc.M114.602870 |
0.444 |
|
| 2014 |
Avanzino BC, Fraser CS. DEAD box unwinding caught in the act. Structure (London, England : 1993). 22: 931-2. PMID 25007220 DOI: 10.1016/J.Str.2014.06.005 |
0.364 |
|
| 2014 |
Andaya A, Villa N, Jia W, Fraser CS, Leary JA. Phosphorylation stoichiometries of human eukaryotic initiation factors. International Journal of Molecular Sciences. 15: 11523-38. PMID 24979134 DOI: 10.3390/Ijms150711523 |
0.485 |
|
| 2014 |
Özeş AR, Feoktistova K, Avanzino BC, Baldwin EP, Fraser CS. Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicases. Nature Protocols. 9: 1645-61. PMID 24945382 DOI: 10.1038/Nprot.2014.112 |
0.322 |
|
| 2013 |
Villa N, Do A, Hershey JW, Fraser CS. Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome. The Journal of Biological Chemistry. 288: 32932-40. PMID 24092755 DOI: 10.1074/Jbc.M113.517011 |
0.556 |
|
| 2013 |
Feoktistova K, Tuvshintogs E, Do A, Fraser CS. Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 13339-44. PMID 23901100 DOI: 10.1073/Pnas.1303781110 |
0.496 |
|
| 2013 |
Virgili G, Frank F, Feoktistova K, Sawicki M, Sonenberg N, Fraser CS, Nagar B. Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A. Structure (London, England : 1993). 21: 517-27. PMID 23478064 DOI: 10.1016/J.Str.2013.01.015 |
0.488 |
|
| 2012 |
Sokabe M, Fraser CS, Hershey JW. The human translation initiation multi-factor complex promotes methionyl-tRNAi binding to the 40S ribosomal subunit. Nucleic Acids Research. 40: 905-13. PMID 21940399 DOI: 10.1093/Nar/Gkr772 |
0.546 |
|
| 2011 |
Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH. Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3). Proceedings of the National Academy of Sciences of the United States of America. 108: 20473-8. PMID 22135459 DOI: 10.1073/Pnas.1116821108 |
0.76 |
|
| 2011 |
Andaya A, Jia W, Sokabe M, Fraser CS, Hershey JW, Leary JA. Phosphorylation of human eukaryotic initiation factor 2γ: novel site identification and targeted PKC involvement. Journal of Proteome Research. 10: 4613-23. PMID 21854064 DOI: 10.1021/Pr200429Y |
0.497 |
|
| 2011 |
Özeş AR, Feoktistova K, Avanzino BC, Fraser CS. Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B. Journal of Molecular Biology. 412: 674-87. PMID 21840318 DOI: 10.1016/J.Jmb.2011.08.004 |
0.42 |
|
| 2011 |
Park JH, Dias CA, Lee SB, Valentini SR, Sokabe M, Fraser CS, Park MH. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes. Protein Engineering, Design & Selection : Peds. 24: 301-9. PMID 21131325 DOI: 10.1093/Protein/Gzq110 |
0.469 |
|
| 2011 |
Lee SB, Park JH, Folk JE, Deck JA, Pegg AE, Sokabe M, Fraser CS, Park MH. Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1). The Biochemical Journal. 433: 205-13. PMID 20942800 DOI: 10.1042/Bj20101322 |
0.405 |
|
| 2010 |
Lindqvist L, Robert F, Merrick W, Kakeya H, Fraser C, Osada H, Pelletier J. Inhibition of translation by cytotrienin A - A member of the ansamycin family Rna. 16: 2404-2413. PMID 20943818 DOI: 10.1261/Rna.2307710 |
0.37 |
|
| 2010 |
Ozes A, Fraser CS. Establishing a Fluorescence-Based Helicase Assay for Monitoring Eukaryotic Protein Synthesis Initiation Biophysical Journal. 98: 262a. DOI: 10.1016/J.Bpj.2009.12.1427 |
0.484 |
|
| 2009 |
Fraser CS. The molecular basis of translational control. Progress in Molecular Biology and Translational Science. 90: 1-51. PMID 20374738 DOI: 10.1016/S1877-1173(09)90001-1 |
0.364 |
|
| 2009 |
Fraser CS, Hershey JW, Doudna JA. The pathway of hepatitis C virus mRNA recruitment to the human ribosome. Nature Structural & Molecular Biology. 16: 397-404. PMID 19287397 DOI: 10.1038/Nsmb.1572 |
0.69 |
|
| 2008 |
Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, Doudna JA, Robinson CV. Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Proceedings of the National Academy of Sciences of the United States of America. 105: 18139-44. PMID 18599441 DOI: 10.1073/Pnas.0801313105 |
0.637 |
|
| 2007 |
Fraser CS, Doudna JA. Quantitative studies of ribosome conformational dynamics. Quarterly Reviews of Biophysics. 40: 163-89. PMID 18072984 DOI: 10.1017/S0033583507004647 |
0.598 |
|
| 2007 |
Pöyry TA, Kaminski A, Connell EJ, Fraser CS, Jackson RJ. The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation. Genes & Development. 21: 3149-62. PMID 18056426 DOI: 10.1101/Gad.439507 |
0.565 |
|
| 2007 |
Fraser CS, Berry KE, Hershey JW, Doudna JA. eIF3j is located in the decoding center of the human 40S ribosomal subunit. Molecular Cell. 26: 811-9. PMID 17588516 DOI: 10.1016/J.Molcel.2007.05.019 |
0.721 |
|
| 2007 |
Damoc E, Fraser CS, Zhou M, Videler H, Mayeur GL, Hershey JW, Doudna JA, Robinson CV, Leary JA. Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Molecular & Cellular Proteomics : McP. 6: 1135-46. PMID 17322308 DOI: 10.1074/Mcp.M600399-Mcp200 |
0.657 |
|
| 2007 |
Fraser CS, Doudna JA. Structural and mechanistic insights into hepatitis C viral translation initiation. Nature Reviews. Microbiology. 5: 29-38. PMID 17128284 DOI: 10.1038/Nrmicro1558 |
0.671 |
|
| 2005 |
Siridechadilok B, Fraser CS, Hall RJ, Doudna JA, Nogales E. Structural roles for human translation factor eIF3 in initiation of protein synthesis. Science (New York, N.Y.). 310: 1513-5. PMID 16322461 DOI: 10.1126/Science.1118977 |
0.73 |
|
| 2005 |
Fraser CS, Hershey JW. Movement in ribosome translocation. Journal of Biology. 4: 8. PMID 15985151 DOI: 10.1186/Jbiol27 |
0.453 |
|
| 2004 |
Ji H, Fraser CS, Yu Y, Leary J, Doudna JA. Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 16990-5. PMID 15563596 DOI: 10.1073/Pnas.0407402101 |
0.699 |
|
| 2004 |
Fraser CS, Lee JY, Mayeur GL, Bushell M, Doudna JA, Hershey JW. The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro. The Journal of Biological Chemistry. 279: 8946-56. PMID 14688252 DOI: 10.1074/Jbc.M312745200 |
0.647 |
|
| 2003 |
Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW. Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3. European Journal of Biochemistry. 270: 4133-9. PMID 14519125 DOI: 10.1046/J.1432-1033.2003.03807.X |
0.558 |
|
| 2003 |
Daughenbaugh KF, Fraser CS, Hershey JW, Hardy ME. The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment. The Embo Journal. 22: 2852-9. PMID 12773399 DOI: 10.1093/Emboj/Cdg251 |
0.553 |
|
| 1999 |
Fraser CS, Pain VM, Morley SJ. Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein. The Biochemical Journal. 342: 519-26. PMID 10477262 |
0.337 |
|
| 1999 |
Fraser CS, Pain VM, Morley SJ. The association of initiation factor 4F with poly(A)-binding protein is enhanced in serum-stimulated Xenopus kidney cells. The Journal of Biological Chemistry. 274: 196-204. PMID 9867830 |
0.342 |
|
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