Joel P Mackay - Publications

Affiliations: 
Molecular Bioscience University of Sydney, Camperdown, New South Wales, Australia 
Area:
nucleosome remodelling and deacetylase (NuRD) complex
Website:
http://sydney.edu.au/science/people/joel.mackay.php

173 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Low JKK, Patel K, Jones N, Solomon P, Norman A, Maxwell JWC, Pachl P, Matthews JM, Payne RJ, Passioura T, Suga H, Walport LJ, Mackay JP. mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. The Journal of Biological Chemistry. 105482. PMID 37992806 DOI: 10.1016/j.jbc.2023.105482  0.332
2021 Jindra M, McKinstry WJ, Nebl T, Bittova L, Ren B, Shaw J, Phan T, Lu L, Low JKK, Mackay JP, Sparrow LG, Lovrecz GO, Hill RJ. Purification of an insect juvenile hormone receptor complex enables insights into its post-translational phosphorylation. The Journal of Biological Chemistry. 101387. PMID 34758356 DOI: 10.1016/j.jbc.2021.101387  0.315
2021 Patel K, Solomon PD, Walshe JL, Ford DJ, Wilkinson-White L, Payne RJ, Low JKK, Mackay JP. BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism. Biochemistry. PMID 33620209 DOI: 10.1021/acs.biochem.0c00816  0.327
2020 Franck C, Foster SR, Johansen-Leete J, Chowdhury S, Cielesh M, Bhusal RP, Mackay JP, Larance M, Stone MJ, Payne RJ. Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 32461364 DOI: 10.1073/Pnas.2000605117  0.379
2020 Zhong Y, Paudel BP, Ryan DP, Low JKK, Franck C, Patel K, Bedward MJ, Torrado M, Payne RJ, van Oijen AM, Mackay JP. CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation. Nature Communications. 11: 1519. PMID 32251276 DOI: 10.1038/S41467-020-15183-2  0.323
2019 Werner MT, Wang H, Hamagami N, Hsu SC, Yano JA, Stonestrom AJ, Behera V, Mackay JP, Blobel GA. Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. The Journal of Biological Chemistry. PMID 31792058 DOI: 10.1074/Jbc.Ra119.010679  0.466
2019 Latham RD, Torrado M, Atto B, Walshe JL, Wilson R, Guss JM, Mackay JP, Tristram S, Gell DA. A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae. Molecular Microbiology. PMID 31742788 DOI: 10.1111/Mmi.14426  0.392
2019 Pierson TM, Otero MG, Grand K, Choi A, Graham JM, Young JI, Mackay JP. The NuRD complex and macrocephaly associated neurodevelopmental disorders. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 31737996 DOI: 10.1002/Ajmg.C.31752  0.328
2019 Doak DG, Denyer GS, Gerrard JA, Mackay JP, Allison JR. Peppy: A Virtual Reality Environment for Exploring the Principles of Polypeptide Structure. Protein Science : a Publication of the Protein Society. PMID 31622516 DOI: 10.1002/Pro.3752  0.307
2019 Mohanty B, Hanson-Manful P, Finn TJ, Chambers CR, McKellar JLO, Macindoe I, Helder S, Setiyaputra S, Zhong Y, Mackay JP, Patrick WM. The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G. Proteins. PMID 30958578 DOI: 10.1002/Prot.25687  0.373
2019 Sharifi Tabar M, Mackay JP, Low JKK. The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex is conserved across multiple cell lines. The Febs Journal. PMID 30828972 DOI: 10.1111/Febs.14800  0.322
2019 De Franco S, Vandenameele J, Brans A, Verlaine O, Bendak K, Damblon C, Matagne A, Segal DJ, Galleni M, Mackay JP, Vandevenne M. Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design. Scientific Reports. 9: 2484. PMID 30792407 DOI: 10.1038/S41598-019-38655-Y  0.403
2018 Lu B, Klingbeil O, Tarumoto Y, Somerville TDD, Huang YH, Wei Y, Wai DC, Low JKK, Milazzo JP, Wu XS, Cao Z, Yan X, Demerdash OE, Huang G, Mackay JP, et al. A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. Cancer Cell. PMID 30503706 DOI: 10.1016/J.Ccell.2018.10.015  0.379
2018 Link S, Spitzer RMM, Sana M, Torrado M, Völker-Albert MC, Keilhauer EC, Burgold T, Pünzeler S, Low JKK, Lindström I, Nist A, Regnard C, Stiewe T, Hendrich B, Imhof A, ... ... Mackay JP, et al. PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex. Nature Communications. 9: 4300. PMID 30327463 DOI: 10.1038/S41467-018-06665-5  0.416
2018 Moghaddas Sani H, Hamzeh-Mivehroud M, Silva AP, Walshe JL, Mohammadi SA, Rahbar-Shahrouziasl M, Abbasi M, Jamshidi O, Low JK, Dastmalchi S, Mackay JP. Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from . Bioimpacts : Bi. 8: 167-176. PMID 30211076 DOI: 10.15171/bi.2018.19  0.385
2018 Wai DC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White LE, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Chalmers JN, Patrick WM, Lu B, Vakoc CR, Blobel G, Mackay JP. The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. The Journal of Biological Chemistry. PMID 29567837 DOI: 10.1074/Jbc.Ra117.000678  0.476
2018 Wai DCC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White L, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Lu B, Vakoc CR, Blobel GA, Mackay JP. Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb6Bgg/Pdb  0.33
2018 Mohanty B, Finn T, Macindoe I, Zhong J, Patrick W, Mackay J. Solution NMR structure of uncharacterized protein YejG representing the first structure from PF13989 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr30370  0.344
2017 Torrado M, Low JKK, Silva APG, Schmidberger JW, Sana M, Sharifi Tabar M, Isilak ME, Winning CS, Kwong C, Bedward MJ, Sperlazza MJ, Williams DC, Shepherd NE, Mackay JP. Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex. The Febs Journal. PMID 29063705 DOI: 10.1111/Febs.14301  0.377
2017 O'Geen H, Ren C, Nicolet CM, Perez AA, Halmai J, Le VM, Mackay JP, Farnham PJ, Segal DJ. dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. Nucleic Acids Research. 45: 9901-9916. PMID 28973434 DOI: 10.1093/Nar/Gkx578  0.309
2017 Zhang X, Farah N, Rolston L, Ericsson DJ, Catanzariti AM, Bernoux M, Ve T, Bendak K, Chen C, Mackay JP, Lawrence GJ, Hardham A, Ellis JG, Williams SJ, Dodds PN, et al. Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P. Molecular Plant Pathology. PMID 28817232 DOI: 10.1111/Mpp.12597  0.425
2017 Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, et al. Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability. Nucleic Acids Research. 45: 1130-1143. PMID 28180284 DOI: 10.1093/Nar/Gkw1014  0.434
2017 Mackay JP, Landsberg MJ, Whitten AE, Bond CS. Whaddaya Know: A Guide to Uncertainty and Subjectivity in Structural Biology. Trends in Biochemical Sciences. PMID 28089412 DOI: 10.1016/J.Tibs.2016.11.002  0.308
2016 Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, et al. Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability. Nucleic Acids Research. PMID 27899603 DOI: 10.1093/nar/gkw1014  0.325
2016 Mohanty B, Helder S, Silva AP, Mackay JP, Ryan DP. The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain. Journal of Molecular Biology. PMID 27591891 DOI: 10.1016/J.Jmb.2016.08.028  0.488
2016 Blythe AJ, Yazar-Klosinski B, Webster MW, Chen E, Vandevenne M, Bendak K, Mackay JP, Hartzog GA, Vrielink A. The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. Protein Science : a Publication of the Protein Society. PMID 27376968 DOI: 10.1002/Pro.2976  0.455
2016 Wai DC, Shihab M, Low JK, Mackay JP. The zinc fingers of YY1 bind single-stranded RNA with low sequence specificity. Nucleic Acids Research. PMID 27369384 DOI: 10.1093/Nar/Gkw590  0.438
2016 Helder S, Blythe AJ, Bond CS, Mackay JP. Determinants of affinity and specificity in RNA-binding proteins. Current Opinion in Structural Biology. 38: 83-91. PMID 27315040 DOI: 10.1016/J.Sbi.2016.05.005  0.431
2016 Low JK, Webb SR, Silva AP, Saathoff H, Ryan DP, Torrado M, Brofelth M, Parker BL, Shepherd NE, Mackay JP. CHD4 is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex. The Journal of Biological Chemistry. PMID 27235397 DOI: 10.1074/Jbc.M115.707018  0.325
2016 Schmidberger JW, Sharifi Tabar M, Torrado M, Silva AP, Landsberg MJ, Brillault L, AlQarni S, Zeng YC, Parker BL, Low JK, Mackay JP. The MTA1 subunit of the Nucleosome Remodeling and Deacetylase complex can recruit two copies of RBBP4/7. Protein Science : a Publication of the Protein Society. PMID 27144666 DOI: 10.1002/Pro.2943  0.396
2016 Luo L, Xue J, Kwan A, Gamsjaeger R, Wielens J, von Kleist L, Cubeddu L, Guo Z, Stow JL, Parker MW, Mackay JP, Robinson PJ. The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements. The Journal of Biological Chemistry. PMID 26893375 DOI: 10.1074/Jbc.M115.703108  0.419
2015 Silva AP, Ryan DP, Galanty Y, Low JK, Vandevenne M, Jackson SP, Mackay JP. The N-terminal region of CHD4 is essential for activity and contains a HMG-box-like-domain that can bind poly(ADP-ribose). The Journal of Biological Chemistry. PMID 26565020 DOI: 10.1074/Jbc.M115.683227  0.419
2015 Stevenson WS, Rabbolini DJ, Beutler L, Chen Q, Gabrielli S, Mackay JP, Brighton TA, Ward CM, Morel-Kopp MC. Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1. Blood. PMID 26316623 DOI: 10.1182/Blood-2015-06-650887  0.322
2015 Mohanty B, Silva AP, Mackay JP, Ryan DP. (1)H, (13)C and (15)N resonance assignments of a C-terminal domain of human CHD1. Biomolecular Nmr Assignments. PMID 26286320 DOI: 10.1007/S12104-015-9631-1  0.469
2015 Stevenson WS, Rabbolini DJ, Brighton T, Mackay J, Ward CM, Morel-Kopp M. Homozygous Mutation of the ETS DNA-Binding Domain of FLI1 Causes a Bleeding Disorder with Giant Alpha Granules Similar to Paris-Trousseau Thrombocytopenia Blood. 126: 78-78. DOI: 10.1182/Blood.V126.23.78.78  0.381
2015 Shepherd NE, Gamsjaeger R, Vandevenne M, Cubeddu L, Mackay JP. Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies Tetrahedron. 71: 813-819. DOI: 10.1016/J.Tet.2014.12.056  0.305
2014 Joseph S, Kwan AH, Stokes PH, Mackay JP, Cubeddu L, Matthews JM. The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4. Plos One. 9: e109108. PMID 25310299 DOI: 10.1371/Journal.Pone.0109108  0.492
2014 Thom CS, Traxler EA, Khandros E, Nickas JM, Zhou OY, Lazarus JE, Silva AP, Prabhu D, Yao Y, Aribeana C, Fuchs SY, Mackay JP, Holzbaur EL, Weiss MJ. Trim58 degrades Dynein and regulates terminal erythropoiesis. Developmental Cell. 30: 688-700. PMID 25241935 DOI: 10.1016/J.Devcel.2014.07.021  0.34
2014 Clifton MK, Westman BJ, Thong SY, O'Connell MR, Webster MW, Shepherd NE, Quinlan KG, Crossley M, Blobel GA, Mackay JP. The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. Plos One. 9: e106011. PMID 25162672 DOI: 10.1371/Journal.Pone.0106011  0.72
2014 Vandevenne M, O'Connell MR, Helder S, Shepherd NE, Matthews JM, Kwan AH, Segal DJ, Mackay JP. Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA. Angewandte Chemie (International Ed. in English). 53: 7848-52. PMID 25044781 DOI: 10.1002/Anie.201402980  0.704
2014 Alqarni SS, Murthy A, Zhang W, Przewloka MR, Silva AP, Watson AA, Lejon S, Pei XY, Smits AH, Kloet SL, Wang H, Shepherd NE, Stokes PH, Blobel GA, Vermeulen M, ... ... Mackay JP, et al. Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex. The Journal of Biological Chemistry. 289: 21844-55. PMID 24920672 DOI: 10.1074/Jbc.M114.558940  0.391
2014 Blythe A, Gunasekara S, Walshe J, Mackay JP, Hartzog GA, Vrielink A. Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5. Protein Expression and Purification. 100: 54-60. PMID 24859675 DOI: 10.1016/J.Pep.2014.05.005  0.433
2014 Dickson CF, Kumar KK, Jacques DA, Malmirchegini GR, Spirig T, Mackay JP, Clubb RT, Guss JM, Gell DA. Structure of the hemoglobin-IsdH complex reveals the molecular basis of iron capture by Staphylococcus aureus. The Journal of Biological Chemistry. 289: 6728-38. PMID 24425866 DOI: 10.1074/Jbc.M113.545566  0.412
2014 Silva AP, Kwan AH, Mackay JP. ¹H, ¹³C and ¹⁵N resonance assignments of an N-terminal domain of CHD4. Biomolecular Nmr Assignments. 8: 137-9. PMID 23417793 DOI: 10.1007/S12104-013-9469-3  0.455
2014 Joseph S, Kwan AH, Mackay JP, Cubeddu L, Matthews JM. Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Biomolecular Nmr Assignments. 8: 141-4. PMID 23417771 DOI: 10.1007/S12104-013-9470-X  0.397
2014 Perkins AC, Gillinder KR, Magor G, Lajoie M, Bailey TL, Tallack MR, Ilsley M, Landsberg M, Mackay JP, Bieker JJ, Peters LL. New Insights into the Mechanism of Dominant Anemia Caused By Zinc Finger Mutations in KLF1 Blood. 124: 740-740. DOI: 10.1182/Blood.V124.21.740.740  0.324
2013 Gamsjaeger R, O'Connell MR, Cubeddu L, Shepherd NE, Lowry JA, Kwan AH, Vandevenne M, Swanton MK, Matthews JM, Mackay JP. A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers. The Journal of Biological Chemistry. 288: 35180-91. PMID 24097990 DOI: 10.1074/Jbc.M113.482075  0.728
2013 Mackay JP, Segal DJ, Crossley M. Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides? Trends in Biochemical Sciences. 38: 421-2. PMID 23992945 DOI: 10.1016/J.Tibs.2013.06.005  0.346
2013 Gamsjaeger R, Kariawasam R, Bang LH, Touma C, Nguyen CD, Matthews JM, Cubeddu L, Mackay JP. Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments. Analytical Biochemistry. 440: 178-85. PMID 23727560 DOI: 10.1016/J.Ab.2013.04.030  0.397
2013 Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood. 121: 5218-27. PMID 23704091 DOI: 10.1182/Blood-2013-03-488080  0.339
2013 Dickson CF, Rich AM, D'Avigdor WM, Collins DA, Lowry JA, Mollan TL, Khandros E, Olson JS, Weiss MJ, Mackay JP, Lay PA, Gell DA. α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond. The Journal of Biological Chemistry. 288: 19986-20001. PMID 23696640 DOI: 10.1074/Jbc.M112.437509  0.344
2013 Vandevenne M, Jacques DA, Artuz C, Nguyen CD, Kwan AH, Segal DJ, Matthews JM, Crossley M, Guss JM, Mackay JP. New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. The Journal of Biological Chemistry. 288: 10616-27. PMID 23436653 DOI: 10.1074/Jbc.M112.441451  0.395
2013 Cordina NM, Liew CK, Gell DA, Fajer PG, Mackay JP, Brown LJ. Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C. Biochemistry. 52: 1950-62. PMID 23425245 DOI: 10.1021/Bi4000172  0.386
2013 Stokes PH, Liew CW, Kwan AH, Foo P, Barker HE, Djamirze A, O'Reilly V, Visvader JE, Mackay JP, Matthews JM. Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8. Journal of Molecular Biology. 425: 1101-10. PMID 23353824 DOI: 10.1016/J.Jmb.2013.01.017  0.428
2012 Gell DA, Grant RP, Mackay JP. The detection and quantitation of protein oligomerization. Advances in Experimental Medicine and Biology. 747: 19-41. PMID 22949109 DOI: 10.1007/978-1-4614-3229-6_2  0.304
2012 Dastmalchi S, Wilkinson-White L, Kwan AH, Gamsjaeger R, Mackay JP, Matthews JM. Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex. Protein Science : a Publication of the Protein Society. 21: 1768-74. PMID 22936624 DOI: 10.1002/Pro.2153  0.494
2012 Bhati M, Lee C, Gadd MS, Jeffries CM, Kwan A, Whitten AE, Trewhella J, Mackay JP, Matthews JM. Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions. Plos One. 7: e40719. PMID 22848397 DOI: 10.1371/Journal.Pone.0040719  0.446
2012 Cordina NM, Liew CK, Gell DA, Fajer PG, Mackay JP, Brown LJ. Interdomain orientation of cardiac troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state. Protein Science : a Publication of the Protein Society. 21: 1376-87. PMID 22811351 DOI: 10.1002/Pro.2124  0.384
2012 McKenzie JL, Duyvestyn JM, Smith T, Bendak K, Mackay J, Cursons R, Cook GM, Arcus VL. Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. Rna (New York, N.Y.). 18: 1267-78. PMID 22539524 DOI: 10.1261/Rna.031229.111  0.334
2012 O'Connell MR, Vandevenne M, Nguyen CD, Matthews JM, Gamsjaeger R, Segal DJ, Mackay JP. Modular assembly of RanBP2-type zinc finger domains to target single-stranded RNA. Angewandte Chemie (International Ed. in English). 51: 5371-5. PMID 22517726 DOI: 10.1002/Anie.201200866  0.686
2012 Bendak K, Loughlin FE, Cheung V, O'Connell MR, Crossley M, Mackay JP. A rapid method for assessing the RNA-binding potential of a protein. Nucleic Acids Research. 40: e105. PMID 22492509 DOI: 10.1093/Nar/Gks285  0.702
2012 Hsieh YS, Wilkinson BL, O'Connell MR, Mackay JP, Matthews JM, Payne RJ. Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Organic Letters. 14: 1910-3. PMID 22455748 DOI: 10.1021/Ol300557G  0.65
2012 Burdach J, O'Connell MR, Mackay JP, Crossley M. Two-timing zinc finger transcription factors liaising with RNA. Trends in Biochemical Sciences. 37: 199-205. PMID 22405571 DOI: 10.1016/J.Tibs.2012.02.001  0.742
2012 Musselman CA, Ramírez J, Sims JK, Mansfield RE, Oliver SS, Denu JM, Mackay JP, Wade PA, Hagman J, Kutateladze TG. Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proceedings of the National Academy of Sciences of the United States of America. 109: 787-92. PMID 22215588 DOI: 10.1073/Pnas.1113655109  0.361
2012 Morris VK, Kwan AH, Mackay JP, Sunde M. Backbone and sidechain ¹H, ¹³C and ¹⁵N chemical shift assignments of the hydrophobin DewA from Aspergillus nidulans. Biomolecular Nmr Assignments. 6: 83-6. PMID 21845363 DOI: 10.1007/S12104-011-9330-5  0.308
2012 Liew CW, Kwan AH, Stokes PH, Mackay JP, Matthews JM. ¹H, ¹⁵N and ¹³C assignments of an intramolecular LMO4-LIM1/CtIP complex. Biomolecular Nmr Assignments. 6: 31-4. PMID 21643835 DOI: 10.1007/S12104-011-9319-0  0.435
2012 Musselman CA, Ramirez J, Sims JK, Mansfield RE, Oliver SS, Denu JM, Mackay JP, Wade PA, Hagman J, Kutateladze TG. Bivalent Recognition of a Single Nucleosome by the Tandem PHD Fingers of CHD4 is Required for CHD4-Mediated Repression Biophysical Journal. 102: 480a. DOI: 10.1016/J.Bpj.2011.11.2630  0.379
2011 Krishna Kumar K, Jacques DA, Pishchany G, Caradoc-Davies T, Spirig T, Malmirchegini GR, Langley DB, Dickson CF, Mackay JP, Clubb RT, Skaar EP, Guss JM, Gell DA. Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH. The Journal of Biological Chemistry. 286: 38439-47. PMID 21917915 DOI: 10.1074/Jbc.M111.287300  0.354
2011 Nunez N, Clifton MM, Funnell AP, Artuz C, Hallal S, Quinlan KG, Font J, Vandevenne M, Setiyaputra S, Pearson RC, Mackay JP, Crossley M. The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain. The Journal of Biological Chemistry. 286: 38190-201. PMID 21908891 DOI: 10.1074/Jbc.M111.301234  0.43
2011 Wilkinson-White L, Gamsjaeger R, Dastmalchi S, Wienert B, Stokes PH, Crossley M, Mackay JP, Matthews JM. Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proceedings of the National Academy of Sciences of the United States of America. 108: 14443-8. PMID 21844373 DOI: 10.1073/Pnas.1105898108  0.453
2011 Wissmueller S, Font J, Liew CW, Cram E, Schroeder T, Turner J, Crossley M, Mackay JP, Matthews JM. Protein-protein interactions: analysis of a false positive GST pulldown result. Proteins. 79: 2365-71. PMID 21638332 DOI: 10.1002/Prot.23068  0.446
2011 Gamsjaeger R, Webb SR, Lamonica JM, Billin A, Blobel GA, Mackay JP. Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Molecular and Cellular Biology. 31: 2632-40. PMID 21555453 DOI: 10.1128/Mcb.05413-11  0.427
2011 Lamonica JM, Deng W, Kadauke S, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proceedings of the National Academy of Sciences of the United States of America. 108: E159-68. PMID 21536911 DOI: 10.1073/Pnas.1102140108  0.392
2011 Mackay JP, Font J, Segal DJ. The prospects for designer single-stranded RNA-binding proteins. Nature Structural & Molecular Biology. 18: 256-61. PMID 21358629 DOI: 10.1038/Nsmb.2005  0.403
2011 Setiyaputra S, Mackay JP, Patrick WM. The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (βα)8 barrel fold. Journal of Molecular Biology. 408: 291-303. PMID 21354426 DOI: 10.1016/J.Jmb.2011.02.048  0.366
2011 Mansfield RE, Musselman CA, Kwan AH, Oliver SS, Garske AL, Davrazou F, Denu JM, Kutateladze TG, Mackay JP. Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. The Journal of Biological Chemistry. 286: 11779-91. PMID 21278251 DOI: 10.1074/Jbc.M110.208207  0.405
2011 Nguyen CD, Mansfield RE, Leung W, Vaz PM, Loughlin FE, Grant RP, Mackay JP. Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA. Journal of Molecular Biology. 407: 273-83. PMID 21256132 DOI: 10.1016/J.Jmb.2010.12.041  0.477
2011 Bieri M, Kwan AH, Mobli M, King GF, Mackay JP, Gooley PR. Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination. The Febs Journal. 278: 704-15. PMID 21214861 DOI: 10.1111/J.1742-4658.2011.08005.X  0.366
2011 Lejon S, Thong SY, Murthy A, AlQarni S, Murzina NV, Blobel GA, Laue ED, Mackay JP. Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. The Journal of Biological Chemistry. 286: 1196-203. PMID 21047798 DOI: 10.1074/Jbc.M110.195842  0.415
2011 Mackay JP, Font J, Segal DJ. Erratum: The prospects for designer single-stranded RNA-binding proteins Nature Structural & Molecular Biology. 18: 516-516. DOI: 10.1038/Nsmb0411-516E  0.345
2011 Musselman CA, Kwan A, Mansfield R, Mackay J, Kutateladze TG. The Tandem PHD Fingers of Chd4 Bind Synergistically to Histone H3 Biophysical Journal. 100: 67a. DOI: 10.1016/J.Bpj.2010.12.567  0.428
2010 Krishna Kumar K, Dickson CF, Weiss MJ, Mackay JP, Gell DA. AHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded state. The Biochemical Journal. 432: 275-82. PMID 20860551 DOI: 10.1042/Bj20100642  0.317
2010 Font J, Mackay JP. Beyond DNA: zinc finger domains as RNA-binding modules. Methods in Molecular Biology (Clifton, N.J.). 649: 479-91. PMID 20680853 DOI: 10.1007/978-1-60761-753-2_29  0.452
2010 Schwalbe M, Dutta K, Libich DS, Venugopal H, Claridge JK, Gell DA, Mackay JP, Edwards PJ, Pascal SM. Two-state conformational equilibrium in the Par-4 leucine zipper domain. Proteins. 78: 2433-49. PMID 20602362 DOI: 10.1002/Prot.22752  0.398
2010 Wilkinson-White LE, Dastmalchi S, Kwan AH, Ryan DP, Mackay JP, Matthews JM. 1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex. Biomolecular Nmr Assignments. 4: 203-6. PMID 20563763 DOI: 10.1007/S12104-010-9240-Y  0.439
2010 Hynson RM, Kwan AH, Jacques DA, Mackay JP, Trewhella J. 1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis. Biomolecular Nmr Assignments. 4: 167-9. PMID 20524093 DOI: 10.1007/S12104-010-9237-6  0.355
2009 Matthews JM, Bhati M, Lehtomaki E, Mansfield RE, Cubeddu L, Mackay JP. It takes two to tango: the structure and function of LIM, RING, PHD and MYND domains. Current Pharmaceutical Design. 15: 3681-96. PMID 19925420 DOI: 10.2174/138161209789271861  0.459
2009 O'Connell MR, Gamsjaeger R, Mackay JP. The structural analysis of protein-protein interactions by NMR spectroscopy. Proteomics. 9: 5224-32. PMID 19834907 DOI: 10.1002/Pmic.200900303  0.705
2009 Talib J, Beck JL, Urathamakul T, Nguyen CD, Aldrich-Wright JR, Mackay JP, Ralph SF. A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity. Chemical Communications (Cambridge, England). 5546-8. PMID 19753352 DOI: 10.1039/B904751D  0.329
2009 Gell DA, Feng L, Zhou S, Jeffrey PD, Bendak K, Gow A, Weiss MJ, Shi Y, Mackay JP. A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin. The Journal of Biological Chemistry. 284: 29462-9. PMID 19706593 DOI: 10.1074/Jbc.M109.027045  0.369
2009 Musselman CA, Mansfield RE, Garske AL, Davrazou F, Kwan AH, Oliver SS, O'Leary H, Denu JM, Mackay JP, Kutateladze TG. Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. The Biochemical Journal. 423: 179-87. PMID 19624289 DOI: 10.1016/J.Bpj.2009.12.2587  0.391
2009 Macindoe I, Glockner L, Vukasin P, Stennard FA, Costa MW, Harvey RP, Mackay JP, Sunde M. Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20. Journal of Molecular Biology. 389: 606-18. PMID 19414016 DOI: 10.1016/J.Jmb.2009.04.056  0.355
2009 Loughlin FE, Mansfield RE, Vaz PM, McGrath AP, Setiyaputra S, Gamsjaeger R, Chen ES, Morris BJ, Guss JM, Mackay JP. The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences. Proceedings of the National Academy of Sciences of the United States of America. 106: 5581-6. PMID 19304800 DOI: 10.1073/Pnas.0802466106  0.464
2009 Lowry JA, Gamsjaeger R, Thong SY, Hung W, Kwan AH, Broitman-Maduro G, Matthews JM, Maduro M, Mackay JP. Structural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domains. The Journal of Biological Chemistry. 284: 5827-35. PMID 19095651 DOI: 10.1074/Jbc.M808712200  0.42
2008 Loughlin FE, Lee M, Guss JM, Mackay JP. Crystallization of a ZRANB2-RNA complex. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 1175-7. PMID 19052380 DOI: 10.1107/S1744309108036993  0.386
2008 Kwan AH, Macindoe I, Vukasin PV, Morris VK, Kass I, Gupte R, Mark AE, Templeton MD, Mackay JP, Sunde M. The Cys3-Cys4 loop of the hydrophobin EAS is not required for rodlet formation and surface activity. Journal of Molecular Biology. 382: 708-20. PMID 18674544 DOI: 10.1016/J.Jmb.2008.07.034  0.4
2008 Bhati M, Lee C, Nancarrow AL, Lee M, Craig VJ, Bach I, Guss JM, Mackay JP, Matthews JM. Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. The Embo Journal. 27: 2018-29. PMID 18583962 DOI: 10.1038/Emboj.2008.123  0.494
2008 Liew CK, Gamsjaeger R, Mansfield RE, Mackay JP. NMR spectroscopy as a tool for the rapid assessment of the conformation of GST-fusion proteins. Protein Science : a Publication of the Protein Society. 17: 1630-5. PMID 18556474 DOI: 10.1110/Ps.034983.108  0.389
2008 Matthews JM, Loughlin FE, Mackay JP. Designed metal-binding sites in biomolecular and bioinorganic interactions. Current Opinion in Structural Biology. 18: 484-90. PMID 18554898 DOI: 10.1016/J.Sbi.2008.04.009  0.318
2008 Gamsjaeger R, Swanton MK, Kobus FJ, Lehtomaki E, Lowry JA, Kwan AH, Matthews JM, Mackay JP. Structural and biophysical analysis of the DNA binding properties of myelin transcription factor 1. The Journal of Biological Chemistry. 283: 5158-67. PMID 18073212 DOI: 10.1074/Jbc.M703772200  0.487
2008 Sunde M, Kwan AH, Templeton MD, Beever RE, Mackay JP. Structural analysis of hydrophobins. Micron (Oxford, England : 1993). 39: 773-84. PMID 17875392 DOI: 10.1016/J.Micron.2007.08.003  0.341
2008 Mackay JP, Sunde M, Lowry JA, Crossley M, Matthews JM. Response to Chatr-aryamontri et al.: Protein interactions: to believe or not to believe? Trends in Biochemical Sciences. 33: 242-243. DOI: 10.1016/J.Tibs.2008.04.003  0.314
2007 Mackay JP, Sunde M, Lowry JA, Crossley M, Matthews JM. Protein interactions: is seeing believing? Trends in Biochemical Sciences. 32: 530-1. PMID 17980603 DOI: 10.1016/J.Tibs.2007.09.006  0.33
2007 Porter CJ, Matthews JM, Mackay JP, Pursglove SE, Schmidberger JW, Leedman PJ, Pero SC, Krag DN, Wilce MC, Wilce JA. Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. Bmc Structural Biology. 7: 58. PMID 17894853 DOI: 10.1186/1472-6807-7-58  0.316
2007 Wang CI, Guncar G, Forwood JK, Teh T, Catanzariti AM, Lawrence GJ, Loughlin FE, Mackay JP, Schirra HJ, Anderson PA, Ellis JG, Dodds PN, Kobe B. Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity. The Plant Cell. 19: 2898-912. PMID 17873095 DOI: 10.1105/Tpc.107.053611  0.405
2007 Kirk EP, Sunde M, Costa MW, Rankin SA, Wolstein O, Castro ML, Butler TL, Hyun C, Guo G, Otway R, Mackay JP, Waddell LB, Cole AD, Hayward C, Keogh A, et al. Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. American Journal of Human Genetics. 81: 280-91. PMID 17668378 DOI: 10.1086/519530  0.32
2007 Gamsjaeger R, Liew CK, Loughlin FE, Crossley M, Mackay JP. Sticky fingers: zinc-fingers as protein-recognition motifs. Trends in Biochemical Sciences. 32: 63-70. PMID 17210253 DOI: 10.1016/J.Tibs.2006.12.007  0.486
2007 Liew CK, Crossley M, Mackay JP, Nicholas HR. Solution structure of the THAP domain from Caenorhabditis elegans C-terminal binding protein (CtBP). Journal of Molecular Biology. 366: 382-90. PMID 17174978 DOI: 10.1016/J.Jmb.2006.11.058  0.484
2006 Loughlin FE, Mackay JP. Zinc fingers are known as domains for binding DNA and RNA. Do they also mediate protein-protein interactions? Iubmb Life. 58: 731-3. PMID 17424912 DOI: 10.1080/15216540600868445  0.488
2006 Kook H, Yung WW, Simpson RJ, Kee HJ, Shin S, Lowry JA, Loughlin FE, Yin Z, Epstein JA, Mackay JP. Analysis of the structure and function of the transcriptional coregulator HOP. Biochemistry. 45: 10584-90. PMID 16939210 DOI: 10.1021/Bi060641S  0.47
2006 Gell DA, Westman BJ, Gorman D, Liew C, Welch JJ, Weiss MJ, Mackay JP. A novel haem-binding interface in the 22 kDa haem-binding protein p22HBP. Journal of Molecular Biology. 362: 287-97. PMID 16905148 DOI: 10.1016/J.Jmb.2006.07.010  0.431
2006 Liew CW, Rand KD, Simpson RJ, Yung WW, Mansfield RE, Crossley M, Proetorius-Ibba M, Nerlov C, Poulsen FM, Mackay JP. Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1. The Journal of Biological Chemistry. 281: 28296-306. PMID 16861236 DOI: 10.1074/Jbc.M602830200  0.432
2006 Ryan DP, Sunde M, Kwan AH, Marianayagam NJ, Nancarrow AL, Vanden Hoven RN, Thompson LS, Baca M, Mackay JP, Visvader JE, Matthews JM. Identification of the key LMO2-binding determinants on Ldb1. Journal of Molecular Biology. 359: 66-75. PMID 16616188 DOI: 10.1016/J.Jmb.2006.02.074  0.441
2006 Kwan AH, Winefield RD, Sunde M, Matthews JM, Haverkamp RG, Templeton MD, Mackay JP. Structural basis for rodlet assembly in fungal hydrophobins. Proceedings of the National Academy of Sciences of the United States of America. 103: 3621-6. PMID 16537446 DOI: 10.1073/Pnas.0505704103  0.355
2006 Lowry JA, Mackay JP. GATA-1: one protein, many partners. The International Journal of Biochemistry & Cell Biology. 38: 6-11. PMID 16095949 DOI: 10.1016/J.Biocel.2005.06.017  0.419
2005 Weiss MJ, Zhou S, Feng L, Gell DA, Mackay JP, Shi Y, Gow AJ. Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia. Annals of the New York Academy of Sciences. 1054: 103-17. PMID 16339656 DOI: 10.1196/Annals.1345.013  0.333
2005 Pursglove SE, Mackay JP. CSL: a notch above the rest. The International Journal of Biochemistry & Cell Biology. 37: 2472-7. PMID 16095948 DOI: 10.1016/J.Biocel.2005.06.013  0.3
2005 Feng L, Zhou S, Gu L, Gell DA, Mackay JP, Weiss MJ, Gow AJ, Shi Y. Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem. Nature. 435: 697-701. PMID 15931225 DOI: 10.1038/Nature03609  0.316
2005 MacKay JP, Muiznieks LD, Toonkool P, Weiss AS. The hydrophobic domain 26 of human tropoelastin is unstructured in solution Journal of Structural Biology. 150: 154-162. PMID 15866738 DOI: 10.1016/J.Jsb.2005.02.005  0.412
2005 Porter CJ, Wilce MC, Mackay JP, Leedman P, Wilce JA. Grb7-SH2 domain dimerisation is affected by a single point mutation. European Biophysics Journal : Ebj. 34: 454-60. PMID 15841400 DOI: 10.1007/S00249-005-0480-1  0.386
2005 Sharpe BK, Liew CK, Kwan AH, Wilce JA, Crossley M, Matthews JM, Mackay JP. Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting. Structure (London, England : 1993). 13: 257-66. PMID 15698569 DOI: 10.1016/J.Str.2004.12.007  0.464
2005 Kwan AH, Fairley K, Anderberg PI, Liew CW, Harding MM, Mackay JP. Solution structure of a recombinant type I sculpin antifreeze protein. Biochemistry. 44: 1980-8. PMID 15697223 DOI: 10.1021/Bi047782J  0.368
2005 Duggin IG, Matthews JM, Dixon NE, Wake RG, Mackay JP. A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis Journal of Biological Chemistry. 280: 13105-13113. PMID 15657033 DOI: 10.1074/Jbc.M414187200  0.385
2005 Liew CK, Simpson RJ, Kwan AH, Crofts LA, Loughlin FE, Matthews JM, Crossley M, Mackay JP. Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction. Proceedings of the National Academy of Sciences of the United States of America. 102: 583-8. PMID 15644435 DOI: 10.1073/Pnas.0407511102  0.462
2004 Westman BJ, Perdomo J, Matthews JM, Crossley M, Mackay JP. Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers. Biochemistry. 43: 13318-27. PMID 15491138 DOI: 10.1021/Bi049506A  0.499
2004 Chow MK, Mackay JP, Whisstock JC, Scanlon MJ, Bottomley SP. Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3. Biochemical and Biophysical Research Communications. 322: 387-94. PMID 15325242 DOI: 10.1016/J.Bbrc.2004.07.131  0.461
2004 Simpson RJ, Yi Lee SH, Bartle N, Sum EY, Visvader JE, Matthews JM, Mackay JP, Crossley M. A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3. The Journal of Biological Chemistry. 279: 39789-97. PMID 15234987 DOI: 10.1074/Jbc.M404130200  0.464
2004 Dastmalchi S, Church WB, Morris MB, Iismaa TP, Mackay JP. Presence of transient helical segments in the galanin-like peptide evident from (1)H NMR, circular dichroism, and prediction studies. Journal of Structural Biology. 146: 261-71. PMID 15099568 DOI: 10.1016/J.Jsb.2004.01.004  0.344
2004 Sunde M, McGrath KC, Young L, Matthews JM, Chua EL, Mackay JP, Death AK. TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer. Cancer Research. 64: 2766-73. PMID 15087392 DOI: 10.1158/0008-5472.Can-03-2093  0.329
2004 Donadini R, Liew CW, Kwan AH, Mackay JP, Fields BA. Crystal and solution structures of a superantigen from Yersinia pseudotuberculosis reveal a jelly-roll fold. Structure (London, England : 1993). 12: 145-56. PMID 14725774 DOI: 10.1016/J.Str.2003.12.002  0.417
2004 Kwan AH, Czolij R, Mackay JP, Crossley M. Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities. Nucleic Acids Research. 31: e124. PMID 14530457 DOI: 10.1093/Nar/Gng124  0.457
2003 Kook H, Lepore JJ, Gitler AD, Lu MM, Wing-Man Yung W, Mackay J, Zhou R, Ferrari V, Gruber P, Epstein JA. Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. The Journal of Clinical Investigation. 112: 863-71. PMID 12975471 DOI: 10.1172/Jci19137  0.301
2003 Westman BJ, Perdomo J, Sunde M, Crossley M, Mackay JP. The C-terminal domain of Eos forms a high order complex in solution. The Journal of Biological Chemistry. 278: 42419-26. PMID 12917396 DOI: 10.1074/Jbc.M306817200  0.434
2003 Kwan AH, Gell DA, Verger A, Crossley M, Matthews JM, Mackay JP. Engineering a protein scaffold from a PHD finger. Structure (London, England : 1993). 11: 803-13. PMID 12842043 DOI: 10.1016/S0969-2126(03)00122-9  0.476
2003 Simpson RJ, Cram ED, Czolij R, Matthews JM, Crossley M, Mackay JP. CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. The Journal of Biological Chemistry. 278: 28011-8. PMID 12736264 DOI: 10.1074/Jbc.M211146200  0.481
2003 Deane JE, Mackay JP, Kwan AH, Sum EY, Visvader JE, Matthews JM. Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4. The Embo Journal. 22: 2224-33. PMID 12727888 DOI: 10.1093/Emboj/Cdg196  0.49
2003 Plambeck CA, Kwan AH, Adams DJ, Westman BJ, van der Weyden L, Medcalf RL, Morris BJ, Mackay JP. The structure of the zinc finger domain from human splicing factor ZNF265 fold. The Journal of Biological Chemistry. 278: 22805-11. PMID 12657633 DOI: 10.1074/Jbc.M301896200  0.491
2002 Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, et al. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 110: 713-23. PMID 12297045 DOI: 10.1016/S0092-8674(02)00932-7  0.342
2002 Gell D, Kong Y, Eaton SA, Weiss MJ, Mackay JP. Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein. The Journal of Biological Chemistry. 277: 40602-9. PMID 12192002 DOI: 10.1074/Jbc.M206084200  0.328
2002 Westman BJ, Mackay JP, Gell D. Ikaros: a key regulator of haematopoiesis. The International Journal of Biochemistry & Cell Biology. 34: 1304-7. PMID 12127581 DOI: 10.1016/S1357-2725(02)00070-5  0.343
2002 Kowalski K, Liew CK, Matthews JM, Gell DA, Crossley M, Mackay JP. Characterization of the conserved interaction between GATA and FOG family proteins. The Journal of Biological Chemistry. 277: 35720-9. PMID 12110675 DOI: 10.1074/Jbc.M204663200  0.491
2002 Sharpe BK, Matthews JM, Kwan AHY, Newton A, Gell DA, Crossley M, Mackay JP. A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution Structure. 10: 639-648. PMID 12015147 DOI: 10.1016/S0969-2126(02)00757-8  0.419
2002 Robson SA, Michie KA, Mackay JP, Harry E, King GF. The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components. Molecular Microbiology. 44: 663-74. PMID 11994149 DOI: 10.1046/J.1365-2958.2002.02920.X  0.36
2002 Fairley K, Westman BJ, Pham LH, Haymet AD, Harding MM, Mackay JP. Type I shorthorn sculpin antifreeze protein: recombinant synthesis, solution conformation, and ice growth inhibition studies. The Journal of Biological Chemistry. 277: 24073-80. PMID 11940576 DOI: 10.1074/Jbc.M200307200  0.341
2002 Liepinsh E, Otting G, Harding MM, Ward LG, Mackay JP, Haymet AD. Solution structure of a hydrophobic analogue of the winter flounder antifreeze protein. European Journal of Biochemistry / Febs. 269: 1259-66. PMID 11856360 DOI: 10.1046/J.1432-1033.2002.02766.X  0.359
2002 Polekhina G, House CM, Traficante N, Mackay JP, Relaix F, Sassoon DA, Parker MW, Bowtell DD. Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nature Structural Biology. 9: 68-75. PMID 11742346 DOI: 10.1038/Nsb743  0.442
2002 Pursglove SE, Mulhern TD, Mackay JP, Hinds MG, Booker GW. The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain. The Journal of Biological Chemistry. 277: 755-62. PMID 11684687 DOI: 10.1074/Jbc.M108318200  0.398
2001 Deane JE, Sum E, Mackay JP, Lindeman GJ, Visvader JE, Matthews JM. Design, production and characterization of FLIN2 and FLIN4: the engineering of intramolecular ldb1:LMO complexes. Protein Engineering. 14: 493-9. PMID 11522923 DOI: 10.1093/Protein/14.7.493  0.5
2001 Newton A, Mackay J, Crossley M. The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA. The Journal of Biological Chemistry. 276: 35794-801. PMID 11445591 DOI: 10.1074/Jbc.M106256200  0.426
2001 Proudfoot EM, Mackay JP, Karuso P. Probing site specificity of DNA binding metallointercalators by NMR spectroscopy and molecular modeling. Biochemistry. 40: 4867-78. PMID 11294655 DOI: 10.1021/Bi001655F  0.347
2001 Mackay JP, Matthews JM, Winefield RD, Mackay LG, Haverkamp RG, Templeton MD. The hydrophobin EAS is largely unstructured in solution and functions by forming amyloid-like structures. Structure (London, England : 1993). 9: 83-91. PMID 11250193 DOI: 10.1016/S0969-2126(00)00559-1  0.354
2001 Liew CK, Kowalski K, Fox AH, Newton A, Sharpe BK, Crossley M, Mackay JP. Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. Structure (London, England : 1993). 8: 1157-66. PMID 11080638 DOI: 10.1016/S0969-2126(00)00527-X  0.468
2000 Tchan MC, Choy KJ, Mackay JP, Lyons ATL, Bains NPS, Weiss AS. Interfacial asparagine residues within an amide tetrad contribute to Max helix-loop-helix leucine zipper homodimer stability Journal of Biological Chemistry. 275: 37454-37461. PMID 10978321 DOI: 10.1074/Jbc.M004264200  0.386
2000 Matthews JM, Young TF, Tucker SP, Mackay JP. The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil. Journal of Virology. 74: 5911-20. PMID 10846072 DOI: 10.1128/Jvi.74.13.5911-5920.2000  0.37
2000 Newton AL, Sharpe BK, Kwan A, Mackay JP, Crossley M. The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules. The Journal of Biological Chemistry. 275: 15128-34. PMID 10748221 DOI: 10.1074/Jbc.M910396199  0.389
2000 Matthews JM, Kowalski K, Liew CK, Sharpe BK, Fox AH, Crossley M, Mackay JP. A class of zinc fingers involved in protein-protein interactions: Biophysical characterization of CCHC fingers from Fog and U-shaped European Journal of Biochemistry. 267: 1030-1038. PMID 10672011 DOI: 10.1046/J.1432-1327.2000.01095.X  0.479
2000 Kowalski K, Czolij R, King G, Crossley M, Mackay J. Solution structure of the N-terminal zinc finger of murine GATA-1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4423  0.306
1999 Zerella R, Evans PA, Ionides JM, Packman LC, Trotter BW, Mackay JP, Williams DH. Autonomous folding of a peptide corresponding to the N-terminal beta-hairpin from ubiquitin. Protein Science : a Publication of the Protein Society. 8: 1320-31. PMID 10386882 DOI: 10.1110/Ps.8.6.1320  0.355
1999 Fox AH, Liew C, Holmes M, Kowalski K, Mackay J, Crossley M. Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. The Embo Journal. 18: 2812-22. PMID 10329627 DOI: 10.1093/Emboj/18.10.2812  0.448
1999 Kowalski K, Czolij R, King GF, Crossley M, Mackay JP. The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. Journal of Biomolecular Nmr. 13: 249-62. PMID 10212985 DOI: 10.1023/A:1008309602929  0.465
1999 King GF, Rowland SL, Pan B, Mackay JP, Mullen GP, Rothfield LI. The dimerization and topological specificity functions of MinE reside in a structurally autonomous C-terminal domain Molecular Microbiology. 31: 1161-1169. PMID 10096083 DOI: 10.1046/J.1365-2958.1999.01256.X  0.424
1999 Crispino JD, Lodish MB, MacKay JP, Orkin SH. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex Molecular Cell. 3: 219-228. PMID 10078204 DOI: 10.1016/S1097-2765(00)80312-3  0.416
1999 Fox AH, Kowalski K, King GF, Mackay JP, Crossley M. Key residues characteristic of GATA N-fingers are recognized by FOG. The Journal of Biological Chemistry. 273: 33595-603. PMID 9837943 DOI: 10.1074/Jbc.273.50.33595  0.476
1998 Diefenbach RJ, Mackay JP, Armati PJ, Cunningham AL. The C-terminal region of the stalk domain of ubiquitous human kinesin heavy chain contains the binding site for kinesin light chain. Biochemistry. 37: 16663-70. PMID 9843434 DOI: 10.1021/Bi981163R  0.303
1998 Mackay JP, Kowalski K, Fox AH, Czolij R, King GF, Crossley M. Involvement of the N-finger in the self-association of GATA-1. The Journal of Biological Chemistry. 273: 30560-7. PMID 9804826 DOI: 10.1074/Jbc.273.46.30560  0.469
1997 Harding MM, Krippner GY, Shelton CJ, Rodger A, Sanders KJ, Mackay JP, Prakash AS. DNA-binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II. Biopolymers. 42: 387-98. PMID 9283289 DOI: 10.1002/(Sici)1097-0282(19971005)42:4<387::Aid-Bip2>3.0.Co;2-M  0.351
1996 Heuer KH, Mackay JP, Podzebenko P, Bains NPS, Weiss AS, King GF, Easterbrook-Smith SB. Development of a sensitive peptide-based immunoassay: Application to detection of the Jun and Fos oncoproteins Biochemistry. 35: 9069-9075. PMID 8703910 DOI: 10.1021/Bi952817O  0.345
1996 Mackay JP, Shelton CJ, Harding MM. Assignment of the 1H NMR spectrum and solution conformation of the antitumour antibiotic ditrisarubicin B Tetrahedron. 52: 5617-5624. DOI: 10.1016/0040-4020(96)00198-6  0.334
1995 Dingley AJ, Mackay JP, Chapman BE, Morris MB, Kuchel PW, Hambly BD, King GF. Measuring protein self-association using pulsed-field-gradient NMR spectroscopy: application to myosin light chain 2. Journal of Biomolecular Nmr. 6: 321-8. PMID 8520223 DOI: 10.1007/Bf00197813  0.314
1995 Junius FK, Mackay JP, Bubb WA, Jensen SA, Weiss AS, King GF. Nuclear magnetic resonance characterization of the Jun leucine zipper domain: unusual properties of coiled-coil interfacial polar residues. Biochemistry. 34: 6164-74. PMID 7742321 DOI: 10.1021/Bi00018A020  0.394
1994 Groves P, Searle MS, Mackay JP, Williams DH. The structure of an asymmetric dimer relevant to the mode of action of the glycopeptide antibiotics. Structure (London, England : 1993). 2: 747-54. PMID 7994574 DOI: 10.1016/S0969-2126(94)00075-1  0.378
1994 Williams DH, Searle MS, Groves P, Mackay JP, Westwell MS, Beauregard DA, Cristofaro MF. Functional roles of natural products: The involvement of extended arrays of weak interactions in cooperative binding phenomena Pure and Applied Chemistry. 66: 1975-1982. DOI: 10.1351/Pac199466101975  0.335
1993 Williams DH, Searle MS, Mackay JP, Gerhard U, Maplestone RA. Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 90: 1172-8. PMID 8433979 DOI: 10.1073/Pnas.90.4.1172  0.312
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