Boris Lenhard - Publications

Affiliations: 
Bergen Center of Computational Science University of Bergen, Bergen, Hordaland, Norway 

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Haberman N, Cheung R, Pizza G, Cvetesic N, Nagy D, Maude H, Blazquez L, Lenhard B, Cebola I, Rutter GA, Martinez-Sanchez A. Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23885. PMID 39139039 DOI: 10.1096/fj.202401078R  0.755
2024 Haberman N, Cheung R, Pizza G, Cvetesic N, Nagy D, Maude H, Blazquez L, Lenhard B, Cebola I, Rutter GA, Martinez-Sanchez A. Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells. Biorxiv : the Preprint Server For Biology. PMID 38798508 DOI: 10.1101/2024.05.13.593867  0.754
2023 Pavlu S, Nikumbh S, Kovacik M, An T, Lenhard B, Simkova H, Navratilova P. Core promoterome of barley embryo. Computational and Structural Biotechnology Journal. 23: 264-277. PMID 38173877 DOI: 10.1016/j.csbj.2023.12.003  0.499
2023 Nikumbh S, Lenhard B. Identifying promoter sequence architectures via a chunking-based algorithm using non-negative matrix factorisation. Plos Computational Biology. 19: e1011491. PMID 37983292 DOI: 10.1371/journal.pcbi.1011491  0.413
2023 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, ... Lenhard B, et al. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Research. PMID 37962376 DOI: 10.1093/nar/gkad1059  0.604
2022 Baranasic D, Hörtenhuber M, Balwierz PJ, Zehnder T, Mukarram AK, Nepal C, Várnai C, Hadzhiev Y, Jimenez-Gonzalez A, Li N, Wragg J, D'Orazio FM, Relic D, Pachkov M, Díaz N, ... ... Lenhard B, et al. Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements. Nature Genetics. PMID 35789323 DOI: 10.1038/s41588-022-01089-w  0.332
2021 Castro-Mondragon JA, Riudavets-Puig R, Rauluseviciute I, Berhanu Lemma R, Turchi L, Blanc-Mathieu R, Lucas J, Boddie P, Khan A, Manosalva Pérez N, Fornes O, Leung TY, Aguirre A, Hammal F, Schmelter D, ... ... Lenhard B, et al. JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles. Nucleic Acids Research. PMID 34850907 DOI: 10.1093/nar/gkab1113  0.606
2021 Weiss FD, Calderon L, Wang YF, Georgieva R, Guo Y, Cvetesic N, Kaur M, Dharmalingam G, Krantz ID, Lenhard B, Fisher AG, Merkenschlager M. Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin. Nature Communications. 12: 2919. PMID 34006846 DOI: 10.1038/s41467-021-23141-9  0.749
2021 D'Orazio FM, Balwierz PJ, González AJ, Guo Y, Hernández-Rodríguez B, Wheatley L, Jasiulewicz A, Hadzhiev Y, Vaquerizas JM, Cairns B, Lenhard B, Müller F. Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization. Developmental Cell. PMID 33651978 DOI: 10.1016/j.devcel.2021.02.007  0.338
2020 Yu C, Cvetesic N, Hisler V, Gupta K, Ye T, Gazdag E, Negroni L, Hajkova P, Berger I, Lenhard B, Müller F, Vincent SD, Tora L. TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage. Nature Communications. 11: 6439. PMID 33353944 DOI: 10.1038/s41467-020-20239-4  0.766
2020 Martín-Durán JM, Vellutini BC, Marlétaz F, Cetrangolo V, Cvetesic N, Thiel D, Henriet S, Grau-Bové X, Carrillo-Baltodano AM, Gu W, Kerbl A, Marquez Y, Bekkouche N, Chourrout D, Gómez-Skarmeta JL, ... ... Lenhard B, et al. Publisher Correction: Conservative route to genome compaction in a miniature annelid. Nature Ecology & Evolution. PMID 33239821 DOI: 10.1038/s41559-020-01366-z  0.713
2020 Martín-Durán JM, Vellutini BC, Marlétaz F, Cetrangolo V, Cvetesic N, Thiel D, Henriet S, Grau-Bové X, Carrillo-Baltodano AM, Gu W, Kerbl A, Marquez Y, Bekkouche N, Chourrout D, Gómez-Skarmeta JL, ... ... Lenhard B, et al. Conservative route to genome compaction in a miniature annelid. Nature Ecology & Evolution. PMID 33199869 DOI: 10.1038/s41559-020-01327-6  0.751
2020 Ramilowski JA, Yip CW, Agrawal S, Chang JC, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, Petri A, Roos L, Severin J, Yasuzawa K, Abugessaisa I, ... ... Lenhard B, et al. Functional annotation of human long noncoding RNAs via molecular phenotyping. Genome Research. PMID 32718982 DOI: 10.1101/Gr.254219.119  0.443
2020 Wragg JW, Roos L, Vucenovic D, Cvetesic N, Lenhard B, Müller F. Embryonic tissue differentiation is characterized by transitions in cell cycle dynamic-associated core promoter regulation. Nucleic Acids Research. PMID 32619237 DOI: 10.1093/Nar/Gkaa563  0.765
2020 Lewis SH, Ross L, Bain SA, Pahita E, Smith SA, Cordaux R, Miska EA, Lenhard B, Jiggins FM, Sarkies P. ------Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods. Plos Genetics. 16: e1008864. PMID 32584820 DOI: 10.1371/Journal.Pgen.1008864  0.394
2020 Nepal C, Taranta A, Hadzhiev Y, Pundhir S, Mydel P, Lenhard B, Müller F, Andersen JB. Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans. Iscience. 23: 101008. PMID 32268280 DOI: 10.1016/J.Isci.2020.101008  0.462
2020 Bonetti A, Agostini F, Suzuki AM, Hashimoto K, Pascarella G, Gimenez J, Roos L, Nash AJ, Ghilotti M, Cameron CJF, Valentine M, Medvedeva YA, Noguchi S, Agirre E, Kashi K, ... ... Lenhard B, et al. RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions. Nature Communications. 11: 1018. PMID 32094342 DOI: 10.1038/S41467-020-14337-6  0.472
2020 Nepal C, Hadzhiev Y, Balwierz P, Tarifeño-Saldivia E, Cardenas R, Wragg JW, Suzuki AM, Carninci P, Peers B, Lenhard B, Andersen JB, Müller F. Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. Nature Communications. 11: 168. PMID 31924754 DOI: 10.1038/S41467-019-13687-0  0.488
2020 Lewis SH, Ross L, Bain SA, Pahita E, Smith SA, Cordaux R, Miska EA, Lenhard B, Jiggins FM, Sarkies P. Methylation is a better predictor of nucleosomal pattern than housekeeping gene status. Plos Genetics. DOI: 10.1371/Journal.Pgen.1008864.S009  0.389
2020 Lewis SH, Ross L, Bain SA, Pahita E, Smith SA, Cordaux R, Miska EA, Lenhard B, Jiggins FM, Sarkies P. Expression patterns of methylated and unmethylated genes for all species (cf Fig 5B). Plos Genetics. DOI: 10.1371/Journal.Pgen.1008864.S006  0.314
2019 Fornes O, Castro-Mondragon JA, Khan A, van der Lee R, Zhang X, Richmond PA, Modi BP, Correard S, Gheorghe M, Baranašić D, Santana-Garcia W, Tan G, Chèneby J, Ballester B, Parcy F, ... ... Lenhard B, et al. JASPAR 2020: update of the open-access database of transcription factor binding profiles. Nucleic Acids Research. PMID 31701148 DOI: 10.1093/Nar/Gkz1001  0.617
2019 Barešić A, Nash AJ, Dahoun T, Howes O, Lenhard B. Understanding the genetics of neuropsychiatric disorders: the potential role of genomic regulatory blocks. Molecular Psychiatry. PMID 31616042 DOI: 10.1038/S41380-019-0518-X  0.429
2019 Tan G, Polychronopoulos D, Lenhard B. CNEr: A toolkit for exploring extreme noncoding conservation. Plos Computational Biology. 15: e1006940. PMID 31449516 DOI: 10.1371/Journal.Pcbi.1006940  0.508
2019 Cvetesic N, Pahita E, Lenhard B. Transcription Start Site Mapping Using Super-low Input Carrier-CAGE. Journal of Visualized Experiments : Jove. PMID 31305534 DOI: 10.3791/59805  0.777
2019 Ferreirós-Vidal I, Carroll T, Zhang T, Lagani V, Ramirez RN, Ing-Simmons E, Garcia A, Cooper L, Liang Z, Papoutsoglou G, Dharmalingam G, Guo Y, Tarazona S, Fernandes SJ, Noori P, ... ... Lenhard B, et al. Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation. Plos Biology. 17: e2006506. PMID 30978178 DOI: 10.1371/Journal.Pbio.2006506  0.393
2019 Newton MD, Taylor BJ, Driessen RPC, Roos L, Cvetesic N, Allyjaun S, Lenhard B, Cuomo ME, Rueda DS. DNA stretching induces Cas9 off-target activity. Nature Structural & Molecular Biology. PMID 30804513 DOI: 10.1038/S41594-019-0188-Z  0.726
2019 Börlin CS, Cvetesic N, Holland P, Bergenholm D, Siewers V, Lenhard B, Nielsen J. Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions. Fems Yeast Research. 19. PMID 30590648 DOI: 10.1093/Femsyr/Foy128  0.774
2019 Khan A, Fornes O, Castro-Mondragon JA, Lee Rvd, Sandelin A, Lenhard B, Wasserman WW, Mathelier A. Facilitating community-based curation of transcription factor binding profiles in JASPAR F1000research. 8. DOI: 10.7490/F1000Research.1116592.1  0.349
2019 Fung TK, Zeisig B, Zarowiecki M, Luo H, Tsai CT, Stanojevic B, Lynn C, Leung AY, Zuna J, Zaliova M, Bornhaeuser M, Von Bonin M, Lenhard B, Huang S, Mufti GJ, et al. Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34-/Lo MLL-Rearranged Leukemia Blood. 134: 3203-3203. DOI: 10.1182/Blood-2019-125078  0.301
2018 Nash AJ, Lenhard B. A Novel Measure of Non-coding Genome Conservation Identifies Genomic Regulatory Blocks Within Primates. Bioinformatics (Oxford, England). PMID 30535005 DOI: 10.1093/Bioinformatics/Bty1014  0.443
2018 Marlétaz F, Firbas PN, Maeso I, Tena JJ, Bogdanovic O, Perry M, Wyatt CDR, de la Calle-Mustienes E, Bertrand S, Burguera D, Acemel RD, van Heeringen SJ, Naranjo S, Herrera-Ubeda C, Skvortsova K, ... ... Lenhard B, et al. Amphioxus functional genomics and the origins of vertebrate gene regulation. Nature. PMID 30464347 DOI: 10.1038/S41586-018-0734-6  0.506
2018 Cvetesic N, Leitch HG, Borkowska M, Müller F, Carninci P, Hajkova P, Lenhard B. SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA. Genome Research. PMID 30404778 DOI: 10.1101/Gr.235937.118  0.779
2018 Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, ... ... Lenhard B, et al. Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation. Nature Immunology. PMID 30127433 DOI: 10.1038/S41590-018-0184-1  0.413
2018 Li C, Lenhard B, Luscombe NM. Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome. Genome Research. PMID 29618487 DOI: 10.1101/Gr.231449.117  0.525
2018 Hill PWS, Leitch HG, Requena CE, Sun Z, Amouroux R, Roman-Trufero M, Borkowska M, Terragni J, Vaisvila R, Linnett S, Bagci H, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, et al. Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte. Nature. PMID 29513657 DOI: 10.1038/Nature25964  0.387
2018 Danks GB, Navratilova P, Lenhard B, Thompson EM. Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate. Bmc Genomics. 19: 164. PMID 29482522 DOI: 10.1186/S12864-018-4504-5  0.515
2018 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, Lee Rvd, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, et al. JASPAR: an open-access database of transcription factor binding profiles F1000research. 7. DOI: 10.7490/F1000Research.1115440.1  0.404
2017 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, et al. JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Research. PMID 29161433 DOI: 10.1093/nar/gkx1188  0.581
2017 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, et al. JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Research. PMID 29140473 DOI: 10.1093/Nar/Gkx1126  0.634
2017 Polychronopoulos D, King JWD, Nash AJ, Tan G, Lenhard B. Conserved non-coding elements: developmental gene regulation meets genome organization. Nucleic Acids Research. PMID 29121339 DOI: 10.1093/Nar/Gkx1074  0.468
2017 Siriboonpiputtana T, Zeisig BB, Zarowiecki M, Fung TK, Mallardo M, Tsai CT, Lau PNI, Hoang QC, Veiga P, Barnes J, Lynn C, Wilson A, Lenhard B, So CWE. Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells. The Embo Journal. PMID 28978671 DOI: 10.15252/Embj.201797994  0.316
2017 Harmston N, Ing-Simmons E, Tan G, Perry M, Merkenschlager M, Lenhard B. Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation. Nature Communications. 8: 441. PMID 28874668 DOI: 10.1038/S41467-017-00524-5  0.426
2017 Cvetesic N, Lenhard B. Core promoters across the genome. Nature Biotechnology. 35: 123-124. PMID 28178253 DOI: 10.1038/Nbt.3788  0.758
2017 Cantone I, Dharmalingam G, Chan YW, Kohler AC, Lenhard B, Merkenschlager M, Fisher AG. Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation. Genome Biology. 18: 2. PMID 28118853 DOI: 10.1186/S13059-016-1136-4  0.314
2016 Cvetesic N, Dulic M, Bilus M, Sostaric N, Lenhard B, Gruic-Sovulj I. Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing. The Journal of Biological Chemistry. 291: 8618-31. PMID 26921320 DOI: 10.1074/Jbc.M115.698225  0.759
2016 Tan G, Lenhard B. TFBSTools: an R/Bioconductor package for transcription factor binding site analysis. Bioinformatics (Oxford, England). PMID 26794315 DOI: 10.1093/Bioinformatics/Btw024  0.496
2016 Haberle V, Lenhard B. Promoter architectures and developmental gene regulation. Seminars in Cell & Developmental Biology. 57: 11-23. PMID 26783721 DOI: 10.1016/J.Semcdb.2016.01.014  0.504
2016 Cheung N, Fung TK, Zeisig BB, Holmes K, Rane JK, Mowen KA, Finn MG, Lenhard B, Chan LC, So CW. Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia. Cancer Cell. 29: 32-48. PMID 26766589 DOI: 10.1016/J.Ccell.2015.12.007  0.359
2015 Stadhouders R, Cico A, Stephen T, Thongjuea S, Kolovos P, Baymaz HI, Yu X, Demmers J, Bezstarosti K, Maas A, Barroca V, Kockx C, Ozgur Z, van Ijcken W, Arcangeli ML, ... ... Lenhard B, et al. Control of developmentally primed erythroid genes by combinatorial co-repressor actions. Nature Communications. 6: 8893. PMID 26593974 DOI: 10.1038/ncomms9893  0.374
2015 Harmston N, Ing-Simmons E, Perry M, Barešić A, Lenhard B. GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data. Bmc Genomics. 16: 963. PMID 26576536 DOI: 10.1186/S12864-015-2140-X  0.446
2015 Mathelier A, Fornes O, Arenillas DJ, Chen CY, Denay G, Lee J, Shi W, Shyr C, Tan G, Worsley-Hunt R, Zhang AW, Parcy F, Lenhard B, Sandelin A, Wasserman WW. JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles. Nucleic Acids Research. PMID 26531826 DOI: 10.1093/Nar/Gkv1176  0.633
2015 Ishibashi M, Manning E, Shoubridge C, Krecsmarik M, Hawkins TA, Giacomotto J, Zhao T, Mueller T, Bader PI, Cheung SW, Stankiewicz P, Bain NL, Hackett A, Reddy CC, Mechaly AS, ... ... Lenhard B, et al. Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene. Human Genetics. PMID 26337422 DOI: 10.1007/S00439-015-1594-X  0.457
2015 Naville M, Ishibashi M, Ferg M, Bengani H, Rinkwitz S, Krecsmarik M, Hawkins TA, Wilson SW, Manning E, Chilamakuri CS, Wilson DI, Louis A, Lucy Raymond F, Rastegar S, Strähle U, ... Lenhard B, et al. Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome. Nature Communications. 6: 6904. PMID 25908307 DOI: 10.1038/Ncomms7904  0.488
2015 Ing-Simmons E, Seitan VC, Faure AJ, Flicek P, Carroll T, Dekker J, Fisher AG, Lenhard B, Merkenschlager M. Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin. Genome Research. 25: 504-13. PMID 25677180 DOI: 10.1101/Gr.184986.114  0.305
2015 Haberle V, Forrest AR, Hayashizaki Y, Carninci P, Lenhard B. CAGEr: precise TSS data retrieval and high-resolution promoterome mining for integrative analyses. Nucleic Acids Research. 43: e51. PMID 25653163 DOI: 10.1093/Nar/Gkv054  0.415
2015 Danks GB, Raasholm M, Campsteijn C, Long AM, Manak JR, Lenhard B, Thompson EM. Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest. Molecular Biology and Evolution. 32: 585-99. PMID 25525214 DOI: 10.1093/Molbev/Msu336  0.424
2014 Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, ... ... Lenhard B, et al. A promoter-level mammalian expression atlas. Nature. 507: 462-70. PMID 24670764 DOI: 10.1038/Nature13182  0.691
2014 Stadhouders R, Aktuna S, Thongjuea S, Aghajanirefah A, Pourfarzad F, van Ijcken W, Lenhard B, Rooks H, Best S, Menzel S, Grosveld F, Thein SL, Soler E. HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. The Journal of Clinical Investigation. 124: 1699-710. PMID 24614105 DOI: 10.1182/Blood.V122.21.43.43  0.403
2014 Pascarella G, Lazarevic D, Plessy C, Bertin N, Akalin A, Vlachouli C, Simone R, Faulkner GJ, Zucchelli S, Kawai J, Daub CO, Hayashizaki Y, Lenhard B, Carninci P, Gustincich S. NanoCAGE analysis of the mouse olfactory epithelium identifies the expression of vomeronasal receptors and of proximal LINE elements. Frontiers in Cellular Neuroscience. 8: 41. PMID 24600346 DOI: 10.3389/Fncel.2014.00041  0.382
2014 Sharma Y, Chilamakuri CS, Bakke M, Lenhard B. Computational characterization of modes of transcriptional regulation of nuclear receptor genes. Plos One. 9: e88880. PMID 24551185 DOI: 10.1371/Journal.Pone.0088880  0.438
2014 Zuin J, Franke V, van Ijcken WF, van der Sloot A, Krantz ID, van der Reijden MI, Nakato R, Lenhard B, Wendt KS. A cohesin-independent role for NIPBL at promoters provides insights in CdLS. Plos Genetics. 10: e1004153. PMID 24550742 DOI: 10.1371/Journal.Pgen.1004153  0.453
2014 Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van IJcken WF, Armant O, Ferg M, Strähle U, Carninci P, ... ... Lenhard B, et al. Two independent transcription initiation codes overlap on vertebrate core promoters. Nature. 507: 381-5. PMID 24531765 DOI: 10.1038/Nature12974  0.758
2014 Mathelier A, Zhao X, Zhang AW, Parcy F, Worsley-Hunt R, Arenillas DJ, Buchman S, Chen CY, Chou A, Ienasescu H, Lim J, Shyr C, Tan G, Zhou M, Lenhard B, et al. JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic Acids Research. 42: D142-7. PMID 24194598 DOI: 10.1093/Nar/Gkt997  0.616
2013 Harmston N, Baresic A, Lenhard B. The mystery of extreme non-coding conservation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130021. PMID 24218634 DOI: 10.1098/Rstb.2013.0021  0.413
2013 Frangini A, Sjöberg M, Roman-Trufero M, Dharmalingam G, Haberle V, Bartke T, Lenhard B, Malumbres M, Vidal M, Dillon N. The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes. Molecular Cell. 51: 647-61. PMID 24034696 DOI: 10.1016/J.Molcel.2013.08.022  0.399
2013 Nepal C, Hadzhiev Y, Previti C, Haberle V, Li N, Takahashi H, Suzuki AM, Sheng Y, Abdelhamid RF, Anand S, Gehrig J, Akalin A, Kockx CE, van der Sloot AA, van Ijcken WF, ... ... Lenhard B, et al. Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis. Genome Research. 23: 1938-50. PMID 24002785 DOI: 10.1101/Gr.153692.112  0.513
2013 Seitan VC, Faure AJ, Zhan Y, McCord RP, Lajoie BR, Ing-Simmons E, Lenhard B, Giorgetti L, Heard E, Fisher AG, Flicek P, Dekker J, Merkenschlager M. Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments. Genome Research. 23: 2066-77. PMID 24002784 DOI: 10.1101/Gr.161620.113  0.459
2013 Harmston N, Lenhard B. Chromatin and epigenetic features of long-range gene regulation. Nucleic Acids Research. 41: 7185-99. PMID 23766291 DOI: 10.1093/Nar/Gkt499  0.409
2013 Armant O, März M, Schmidt R, Ferg M, Diotel N, Ertzer R, Bryne JC, Yang L, Baader I, Reischl M, Legradi J, Mikut R, Stemple D, van IJcken W, van der Sloot A, ... Lenhard B, et al. Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos. Developmental Biology. 380: 351-62. PMID 23684812 DOI: 10.1016/J.Ydbio.2013.05.006  0.501
2013 Thongjuea S, Stadhouders R, Grosveld FG, Soler E, Lenhard B. r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data. Nucleic Acids Research. 41: e132. PMID 23671339 DOI: 10.1093/Nar/Gkt373  0.423
2013 Ghamari A, van de Corput MP, Thongjuea S, van Cappellen WA, van Ijcken W, van Haren J, Soler E, Eick D, Lenhard B, Grosveld FG. In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes & Development. 27: 767-77. PMID 23592796 DOI: 10.1101/Gad.216200.113  0.412
2013 Sheffield NC, Thurman RE, Song L, Safi A, Stamatoyannopoulos JA, Lenhard B, Crawford GE, Furey TS. Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions. Genome Research. 23: 777-88. PMID 23482648 DOI: 10.1101/Gr.152140.112  0.467
2013 Mylona A, Andrieu-Soler C, Thongjuea S, Martella A, Soler E, Jorna R, Hou J, Kockx C, van Ijcken W, Lenhard B, Grosveld F. Genome-wide analysis shows that Ldb1 controls essential hematopoietic genes/pathways in mouse early development and reveals novel players in hematopoiesis. Blood. 121: 2902-13. PMID 23390196 DOI: 10.1182/Blood-2012-11-467654  0.454
2013 Danks G, Campsteijn C, Parida M, Butcher S, Doddapaneni H, Fu B, Petrin R, Metpally R, Lenhard B, Wincker P, Chourrout D, Thompson EM, Manak JR. OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica. Nucleic Acids Research. 41: D845-53. PMID 23185044 DOI: 10.1093/Nar/Gks1159  0.51
2012 Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, ... ... Lenhard B, et al. The accessible chromatin landscape of the human genome. Nature. 489: 75-82. PMID 22955617 DOI: 10.1038/Nature11232  0.47
2012 van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, et al. A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Molecular and Cellular Biology. 32: 3814-22. PMID 22801375 DOI: 10.1128/Mcb.05938-11  0.435
2012 Carvalho RH, Haberle V, Hou J, van Gent T, Thongjuea S, van Ijcken W, Kockx C, Brouwer R, Rijkers E, Sieuwerts A, Foekens J, van Vroonhoven M, Aerts J, Grosveld F, Lenhard B, et al. Genome-wide DNA methylation profiling of non-small cell lung carcinomas. Epigenetics & Chromatin. 5: 9. PMID 22726460 DOI: 10.1186/1756-8935-5-9  0.366
2012 Sleutels F, Soochit W, Bartkuhn M, Heath H, Dienstbach S, Bergmaier P, Franke V, Rosa-Garrido M, van de Nobelen S, Caesar L, van der Reijden M, Bryne JC, van Ijcken W, Grootegoed JA, Delgado MD, ... Lenhard B, et al. The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics & Chromatin. 5: 8. PMID 22709888 DOI: 10.1186/1756-8935-5-8  0.511
2012 Haberle V, Lenhard B. Dissecting genomic regulatory elements in vivo. Nature Biotechnology. 30: 504-6. PMID 22678387 DOI: 10.1038/Nbt.2266  0.418
2012 Schroder K, Irvine KM, Taylor MS, Bokil NJ, Le Cao KA, Masterman KA, Labzin LI, Semple CA, Kapetanovic R, Fairbairn L, Akalin A, Faulkner GJ, Baillie JK, Gongora M, Daub CO, ... ... Lenhard B, et al. Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the United States of America. 109: E944-53. PMID 22451944 DOI: 10.1073/Pnas.1110156109  0.418
2012 Lenhard B, Sandelin A, Carninci P. Metazoan promoters: emerging characteristics and insights into transcriptional regulation. Nature Reviews. Genetics. 13: 233-45. PMID 22392219 DOI: 10.1038/Nrg3163  0.48
2012 Plessy C, Pascarella G, Bertin N, Akalin A, Carrieri C, Vassalli A, Lazarevic D, Severin J, Vlachouli C, Simone R, Faulkner GJ, Kawai J, Daub CO, Zucchelli S, Hayashizaki Y, ... ... Lenhard B, et al. Promoter architecture of mouse olfactory receptor genes. Genome Research. 22: 486-97. PMID 22194471 DOI: 10.1101/Gr.126201.111  0.48
2012 Stadhouders R, Thongjuea S, Andrieu-Soler C, Palstra RJ, Bryne JC, van den Heuvel A, Stevens M, de Boer E, Kockx C, van der Sloot A, van den Hout M, van Ijcken W, Eick D, Lenhard B, Grosveld F, et al. Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. The Embo Journal. 31: 986-99. PMID 22157820 DOI: 10.1038/Emboj.2011.450  0.459
2012 Taniya T, Tanaka S, Yamaguchi-Kabata Y, Hanaoka H, Yamasaki C, Maekawa H, Barrero RA, Lenhard B, Datta MW, Shimoyama M, Bumgarner R, Chakraborty R, Hopkinson I, Jia L, Hide W, et al. A prioritization analysis of disease association by data-mining of functional annotation of human genes. Genomics. 99: 1-9. PMID 22019378 DOI: 10.1016/J.Ygeno.2011.10.002  0.366
2011 Fredman D, Dong X, Lenhard B. Making enhancers from spare parts of the genome. Genome Biology. 12: 138. PMID 22206586 DOI: 10.1186/Gb-2011-12-12-138  0.736
2011 Ribeiro de Almeida C, Stadhouders R, de Bruijn MJ, Bergen IM, Thongjuea S, Lenhard B, van Ijcken W, Grosveld F, Galjart N, Soler E, Hendriks RW. The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity. 35: 501-13. PMID 22035845 DOI: 10.1016/J.Immuni.2011.07.014  0.397
2011 Royo JL, Hidalgo C, Roncero Y, Seda MA, Akalin A, Lenhard B, Casares F, Gómez-Skarmeta JL. Dissecting the transcriptional regulatory properties of human chromosome 16 highly conserved non-coding regions. Plos One. 6: e24824. PMID 21935474 DOI: 10.1371/Journal.Pone.0024824  0.382
2011 Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, ... ... Lenhard B, et al. Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nature Genetics. 43: 607-11. PMID 21532573 DOI: 10.1038/Ng.825  0.408
2010 Denoeud F, Henriet S, Mungpakdee S, Aury JM, Da Silva C, Brinkmann H, Mikhaleva J, Olsen LC, Jubin C, Cañestro C, Bouquet JM, Danks G, Poulain J, Campsteijn C, Adamski M, ... ... Lenhard B, et al. Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate. Science (New York, N.Y.). 330: 1381-5. PMID 21097902 DOI: 10.1126/Science.1194167  0.445
2010 Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, ... ... Lenhard B, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell. 140: 744-52. PMID 20211142 DOI: 10.1016/J.Cell.2010.01.044  0.42
2010 Soler E, Andrieu-Soler C, de Boer E, Bryne JC, Thongjuea S, Stadhouders R, Palstra RJ, Stevens M, Kockx C, van Ijcken W, Hou J, Steinhoff C, Rijkers E, Lenhard B, Grosveld F. The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation. Genes & Development. 24: 277-89. PMID 20123907 DOI: 10.1101/Gad.551810  0.453
2010 Dong X, Akalin A, Sharma Y, Lenhard B. Translog, a web browser for studying the expression divergence of homologous genes. Bmc Bioinformatics. 11: S59. PMID 20122234 DOI: 10.1186/1471-2105-11-S1-S59  0.754
2010 Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes Ø, Engström PG, Alonso ME, de la Calle Mustienes E, Gómez Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, ... ... Lenhard B, et al. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proceedings of the National Academy of Sciences of the United States of America. 107: 775-80. PMID 20080751 DOI: 10.1073/Pnas.0911591107  0.367
2010 Navratilova P, Fredman D, Lenhard B, Becker TS. Regulatory divergence of the duplicated chromosomal loci sox11a/b by subpartitioning and sequence evolution of enhancers in zebrafish Molecular Genetics and Genomics. 283: 171-184. PMID 20039180 DOI: 10.1007/S00438-009-0503-1  0.462
2010 Portales-Casamar E, Thongjuea S, Kwon AT, Arenillas D, Zhao X, Valen E, Yusuf D, Lenhard B, Wasserman WW, Sandelin A. JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles. Nucleic Acids Research. 38: D105-10. PMID 19906716 DOI: 10.1093/Nar/Gkp950  0.637
2009 Dong X, Navratilova P, Fredman D, Drivenes Ø, Becker TS, Lenhard B. Exonic remnants of whole-genome duplication reveal cis-regulatory function of coding exons Nucleic Acids Research. 38: 1071-1085. PMID 19969543 DOI: 10.1093/Nar/Gkp1124  0.727
2009 Roider HG, Lenhard B, Kanhere A, Haas SA, Vingron M. CpG-depleted promoters harbor tissue-specific transcription factor binding signals - Implications for motif overrepresentation analyses Nucleic Acids Research. 37: 6305-6315. PMID 19736212 DOI: 10.1093/Nar/Gkp682  0.477
2009 Dong X, Fredman D, Lenhard B. Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes. Genome Biology. 10: R86. PMID 19698106 DOI: 10.1186/Gb-2009-10-8-R86  0.745
2009 Bessa J, Tena JJ, de la Calle-Mustienes E, Fernández-Miñán A, Naranjo S, Fernández A, Montoliu L, Akalin A, Lenhard B, Casares F, Gómez-Skarmeta JL. Zebrafish enhancer detection (ZED) vector: a new tool to facilitate transgenesis and the functional analysis of cis-regulatory regions in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2409-17. PMID 19653328 DOI: 10.1002/Dvdy.22051  0.46
2009 Fredman D, Engström PG, Lenhard B. Web-based tools and approaches to study long-range gene regulation in Metazoa. Briefings in Functional Genomics & Proteomics. 8: 231-42. PMID 19605518 DOI: 10.1093/Bfgp/Elp023  0.505
2009 Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, ... ... Lenhard B, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics. 41: 553-62. PMID 19377474 DOI: 10.1038/Ng.375  0.462
2009 Akalin A, Fredman D, Arner E, Dong X, Bryne JC, Suzuki H, Daub CO, Hayashizaki Y, Lenhard B. Transcriptional features of genomic regulatory blocks. Genome Biology. 10: R38. PMID 19374772 DOI: 10.1186/Gb-2009-10-4-R38  0.772
2009 Navratilova P, Fredman D, Hawkins TA, Turner K, Lenhard B, Becker TS. Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Developmental Biology. 327: 526-40. PMID 19073165 DOI: 10.1016/J.Ydbio.2008.10.044  0.455
2008 Engström PG, Fredman D, Lenhard B. Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes. Genome Biology. 9: R34. PMID 18279518 DOI: 10.1186/Gb-2008-9-2-R34  0.497
2008 Kemmer D, Podowski RM, Yusuf D, Brumm J, Cheung W, Wahlestedt C, Lenhard B, Wasserman WW. Gene characterization index: assessing the depth of gene annotation. Plos One. 3: e1440. PMID 18213364 DOI: 10.1371/Journal.Pone.0001440  0.656
2008 Andersen MC, Engström PG, Lithwick S, Arenillas D, Eriksson P, Lenhard B, Wasserman WW, Odeberg J. In silico detection of sequence variations modifying transcriptional regulation. Plos Computational Biology. 4: e5. PMID 18208319 DOI: 10.1371/Journal.Pcbi.0040005  0.675
2008 Yamasaki C, Murakami K, Fujii Y, Sato Y, Harada E, Takeda J, Taniya T, Sakate R, Kikugawa S, Shimada M, Tanino M, Koyanagi KO, Barrero RA, Gough C, ... ... Lenhard B, et al. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Research. 36: D793-9. PMID 18089548 DOI: 10.1093/Nar/Gkm999  0.45
2008 Bryne JC, Valen E, Tang MH, Marstrand T, Winther O, da Piedade I, Krogh A, Lenhard B, Sandelin A. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Research. 36: D102-6. PMID 18006571 DOI: 10.1093/Nar/Gkm955  0.35
2007 Kikuta H, Fredman D, Rinkwitz S, Lenhard B, Becker TS. Retroviral enhancer detection insertions in zebrafish combined with comparative genomics reveal genomic regulatory blocks - A fundamental feature of vertebrate genomes Genome Biology. 8. PMID 18047696 DOI: 10.1186/Gb-2007-8-S1-S4  0.523
2007 Engström PG, Ho Sui SJ, Drivenes O, Becker TS, Lenhard B. Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Genome Research. 17: 1898-908. PMID 17989259 DOI: 10.1101/Gr.6669607  0.516
2007 Sheng Y, Engström PG, Lenhard B. Mammalian microRNA prediction through a support vector machine model of sequence and structure. Plos One. 2: e946. PMID 17895987 DOI: 10.1371/Journal.Pone.0000946  0.332
2007 Becker TS, Lenhard B. The random versus fragile breakage models of chromosome evolution: A matter of resolution Molecular Genetics and Genomics. 278: 487-491. PMID 17851692 DOI: 10.1007/S00438-007-0287-0  0.437
2007 Sandelin A, Carninci P, Lenhard B, Ponjavic J, Hayashizaki Y, Hume DA. Mammalian RNA polymerase II core promoters: insights from genome-wide studies. Nature Reviews. Genetics. 8: 424-36. PMID 17486122 DOI: 10.1038/Nrg2026  0.527
2007 Kikuta H, Laplante M, Navratilova P, Komisarczuk AZ, Engström PG, Fredman D, Akalin A, Caccamo M, Sealy I, Howe K, Ghislain J, Pezeron G, Mourrain P, Ellingsen S, Oates AC, ... ... Lenhard B, et al. Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates. Genome Research. 17: 545-55. PMID 17387144 DOI: 10.1101/Gr.6086307  0.486
2007 Pang KC, Stephen S, Dinger ME, Engström PG, Lenhard B, Mattick JS. RNAdb 2.0--an expanded database of mammalian non-coding RNAs. Nucleic Acids Research. 35: D178-82. PMID 17145715 DOI: 10.1093/Nar/Gkl926  0.404
2007 Vidal OM, Merino R, Rico-Bautista E, Fernandez-Perez L, Chia DJ, Woelfle J, Ono M, Lenhard B, Norstedt G, Rotwein P, Flores-Morales A. In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver. Molecular Endocrinology (Baltimore, Md.). 21: 293-311. PMID 17008382 DOI: 10.1210/Me.2006-0096  0.477
2007 Carninci P, Sandelin A, Lenhard B, Katayama S, Shimokawa K, Ponjavic J, Semple CAM, Taylor MS, Engström G PG, Frith MC, Forrest ARR, Alkema WB, Tan SL, Plessy C, Kodzius R, et al. Erratum: Corrigendum: Genome-wide analysis of mammalian promoter architecture and evolution Nature Genetics. 39: 1174-1174. DOI: 10.1038/Ng0907-1174B  0.378
2006 Bailey PJ, Klos JM, Andersson E, Karlén M, Källström M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J. A global genomic transcriptional code associated with CNS-expressed genes. Experimental Cell Research. 312: 3108-19. PMID 16919269 DOI: 10.1016/J.Yexcr.2006.06.017  0.559
2006 Ponjavic J, Lenhard B, Kai C, Kawai J, Carninci P, Hayashizaki Y, Sandelin A. Transcriptional and structural impact of TATA-initiation site spacing in mammalian core promoters. Genome Biology. 7: R78. PMID 16916456 DOI: 10.1186/Gb-2006-7-8-R78  0.433
2006 Maeda N, Kasukawa T, Oyama R, Gough J, Frith M, Engström PG, Lenhard B, Aturaliya RN, Batalov S, Beisel KW, Bult CJ, Fletcher CF, Forrest AR, Furuno M, Hill D, et al. Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. Plos Genetics. 2: e62. PMID 16683036 DOI: 10.1371/Journal.Pgen.0020062  0.446
2006 Engström PG, Suzuki H, Ninomiya N, Akalin A, Sessa L, Lavorgna G, Brozzi A, Luzi L, Tan SL, Yang L, Kunarso G, Ng EL, Batalov S, Wahlestedt C, Kai C, ... ... Lenhard B, et al. Complex Loci in human and mouse genomes. Plos Genetics. 2: e47. PMID 16683030 DOI: 10.1371/Journal.Pgen.0020047  0.496
2006 Carninci P, Sandelin A, Lenhard B, Katayama S, Shimokawa K, Ponjavic J, Semple CA, Taylor MS, Engström PG, Frith MC, Forrest AR, Alkema WB, Tan SL, Plessy C, Kodzius R, et al. Genome-wide analysis of mammalian promoter architecture and evolution. Nature Genetics. 38: 626-35. PMID 16645617 DOI: 10.1038/Ng1789  0.525
2006 Andersen M, Lenhard B, Whatling C, Eriksson P, Odeberg J. Alternative promoter usage of the membrane glycoprotein CD36. Bmc Molecular Biology. 7: 8. PMID 16515687 DOI: 10.1186/1471-2199-7-8  0.328
2006 Ǵmez-Skarmeta JL, Lenhard B, Becker TS. New technologies, new findings, and new concepts in the study of vertebrate cis-regulatory sequences Developmental Dynamics. 235: 870-885. PMID 16395688 DOI: 10.1002/Dvdy.20659  0.52
2006 Vlieghe D, Sandelin A, De Bleser PJ, Vleminckx K, Wasserman WW, van Roy F, Lenhard B. A new generation of JASPAR, the open-access repository for transcription factor binding site profiles. Nucleic Acids Research. 34: D95-7. PMID 16381983 DOI: 10.1093/Nar/Gkj115  0.665
2005 Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, ... ... Lenhard B, et al. Antisense transcription in the mammalian transcriptome. Science (New York, N.Y.). 309: 1564-6. PMID 16141073 DOI: 10.1126/Science.1112009  0.48
2005 Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, et al. The transcriptional landscape of the mammalian genome. Science (New York, N.Y.). 309: 1559-63. PMID 16141072 DOI: 10.1126/Science.1112014  0.514
2005 Ståhlberg N, Merino R, Hernández LH, Fernández-Pérez L, Sandelin A, Engström P, Tollet-Egnell P, Lenhard B, Flores-Morales A. Exploring hepatic hormone actions using a compilation of gene expression profiles. Bmc Physiology. 5: 8. PMID 15953391 DOI: 10.1186/1472-6793-5-8  0.361
2005 Mottagui-Tabar S, Faghihi MA, Mizuno Y, Engström PG, Lenhard B, Wasserman WW, Wahlestedt C. Identification of functional SNPs in the 5-prime flanking sequences of human genes. Bmc Genomics. 6: 18. PMID 15717931 DOI: 10.1186/1471-2164-6-18  0.63
2005 Pang KC, Stephen S, Engström PG, Tajul-Arifin K, Chen W, Wahlestedt C, Lenhard B, Hayashizaki Y, Mattick JS. RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Research. 33: D125-30. PMID 15608161 DOI: 10.1093/Nar/Gki089  0.393
2004 Kemmer D, Faxén M, Hodges E, Lim J, Herzog E, Ljungström E, Lundmark A, Olsen MK, Podowski R, Sonnhammer EL, Nilsson P, Reimers M, Lenhard B, Roberds SL, Wahlestedt C, et al. Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies. Comparative and Functional Genomics. 5: 584-95. PMID 18629180 DOI: 10.1002/Cfg.443  0.645
2004 Sandelin A, Bailey P, Bruce S, Engström PG, Klos JM, Wasserman WW, Ericson J, Lenhard B. Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes. Bmc Genomics. 5: 99. PMID 15613238 DOI: 10.1186/1471-2164-5-99  0.712
2004 Katzov H, Bennet AM, Kehoe P, Wiman B, Gatz M, Blennow K, Lenhard B, Pedersen NL, de Faire U, Prince JA. A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity. Human Molecular Genetics. 13: 2647-57. PMID 15367486 DOI: 10.1093/Hmg/Ddh286  0.304
2004 Alkema WB, Lenhard B, Wasserman WW. Regulog analysis: detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus. Genome Research. 14: 1362-73. PMID 15231752 DOI: 10.1101/Gr.2242604  0.646
2004 Sandelin A, Wasserman WW, Lenhard B. ConSite: web-based prediction of regulatory elements using cross-species comparison. Nucleic Acids Research. 32: W249-52. PMID 15215389 DOI: 10.1093/Nar/Gkh372  0.624
2004 Imanishi T, Itoh T, Suzuki Y, O'Donovan C, Fukuchi S, Koyanagi KO, Barrero RA, Tamura T, Yamaguchi-Kabata Y, Tanino M, Yura K, Miyazaki S, Ikeo K, Homma K, Kasprzyk A, ... ... Lenhard B, et al. Integrative annotation of 21,037 human genes validated by full-length cDNA clones. Plos Biology. 2: e162. PMID 15103394 DOI: 10.1371/Journal.Pbio.0020162  0.46
2004 Fredman D, Munns G, Rios D, Sjöholm F, Siegfried M, Lenhard B, Lehväslaiho H, Brookes AJ. HGVbase: a curated resource describing human DNA variation and phenotype relationships Nucleic Acids Research. 32: 516-519. PMID 14681471 DOI: 10.1093/Nar/Gkh111  0.353
2004 Sandelin A, Alkema W, Engström P, Wasserman WW, Lenhard B. JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Research. 32: D91-4. PMID 14681366 DOI: 10.1093/Nar/Gkh012  0.685
2004 Geijer J, Lenhard B, Merino-Martinez R, Norstedt G, Flores-Morales A. Grid Computing For The Analysis Of Regulatory Elements In Co-Regulated Sets Of Genes Parallel Processing Letters. 14: 137-150. DOI: 10.1142/S0129626404001799  0.425
2003 Sandelin A, Höglund A, Lenhard B, Wasserman WW. Integrated analysis of yeast regulatory sequences for biologically linked clusters of genes Functional and Integrative Genomics. 3: 125-134. PMID 12827523 DOI: 10.1007/S10142-003-0086-6  0.698
2003 Lenhard B, Wahlestedt C, Wasserman WW. GeneLynx mouse: integrated portal to the mouse genome. Genome Research. 13: 1501-4. PMID 12819149 DOI: 10.1101/Gr.951403  0.66
2003 Lenhard B, Sandelin A, Mendoza L, Engström P, Jareborg N, Wasserman WW. Identification of conserved regulatory elements by comparative genome analysis. Journal of Biology. 2: 13. PMID 12760745 DOI: 10.1186/1475-4924-2-13  0.66
2002 Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, ... ... Lenhard B, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 420: 563-73. PMID 12466851 DOI: 10.1038/Nature01266  0.46
2002 Lenhard B, Wasserman WW. TFBS: Computational framework for transcription factor binding site analysis. Bioinformatics (Oxford, England). 18: 1135-6. PMID 12176838 DOI: 10.1093/Bioinformatics/18.8.1135  0.607
2001 Lenhard B, Hayes WS, Wasserman WW. GeneLynx: A Gene-Centric Portal to the Human Genome Genome Research. 11: 2151-2157. PMID 11731507 DOI: 10.1101/Gr.199801  0.434
1998 Lenhard B, Prætorius-Ibba M, Filipic S, Söll D, Weygand-Durasevic I. C-terminal truncation of yeast SerRS is toxic for Saccharomyces cerevisiae due to altered mechanism of substrate recognition. Febs Letters. 439: 235-240. PMID 9845329 DOI: 10.1016/S0014-5793(98)01376-3  0.367
1997 Lenhard B, Filipić S, Landeka I, Škrtić I, Söll D, Weygand-Durašević I. Defining the Active Site of Yeast Seryl-tRNA Synthetase MUTATIONS IN MOTIF 2 LOOP RESIDUES AFFECT tRNA-DEPENDENT AMINO ACID RECOGNITION Journal of Biological Chemistry. 272: 1136-1141. PMID 8995413 DOI: 10.1074/Jbc.272.2.1136  0.434
1996 Weygand-Durasevic I, Lenhard B, Filipic S, Söll D. The C-terminal Extension of Yeast Seryl-tRNA Synthetase Affects Stability of the Enzyme and Its Substrate Affinity Journal of Biological Chemistry. 271: 2455-2461. PMID 8576207 DOI: 10.1074/Jbc.271.5.2455  0.384
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