Ayyalusamy Ramamoorthy, Ph.D - Publications

Affiliations: 
1996- Chemistry and Biophysics University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
NMR, Biophysics, Chemistry, Membrane proteins, Amyloid proteins
Website:
http://rams.biop.lsa.umich.edu/home

276 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ravula T, Ramamoorthy A. Magnetic-alignment of polymer macro-nanodiscs enables residual dipolar couplings based high-resolution structural studies by NMR. Angewandte Chemie (International Ed. in English). PMID 31310700 DOI: 10.1002/anie.201907655  1
2019 Mahajan M, Ravula T, Prade E, Anantharamaiah GM, Ramamoorthy A. Probing membrane enhanced protein-protein interactions in a minimal redox complex of cytochrome-P450 and P450-reductase. Chemical Communications (Cambridge, England). PMID 31041432 DOI: 10.1039/c9cc01630a  1
2019 Brender JR, Ghosh A, Kotler SA, Krishnamoorthy J, Bera S, Morris V, Sil TB, Garai K, Reif B, Bhunia A, Ramamoorthy A. Probing transient non-native states in amyloid beta fiber elongation by NMR. Chemical Communications (Cambridge, England). PMID 30917192 DOI: 10.1039/c9cc01067j  1
2019 Ravula T, Hardin NZ, Ramamoorthy A. Polymer nanodiscs: Advantages and limitations. Chemistry and Physics of Lipids. 219: 45-49. PMID 30707909 DOI: 10.1016/j.chemphyslip.2019.01.010  1
2019 Hardin NZ, Ravula T, Mauro GD, Ramamoorthy A. Hydrophobic Functionalization of Polyacrylic Acid as a Versatile Platform for the Development of Polymer Lipid Nanodisks. Small (Weinheim An Der Bergstrasse, Germany). e1804813. PMID 30667600 DOI: 10.1002/smll.201804813  1
2018 Ravula T, Hardin NZ, Di Mauro GM, Ramamoorthy A. Styrene maleic acid derivates to enhance the applications of bio-inspired polymer based lipid-nanodiscs. European Polymer Journal. 108: 597-602. PMID 31105326 DOI: 10.1016/j.eurpolymj.2018.09.048  1
2018 Ramadugu VSK, Di Mauro GM, Ravula T, Ramamoorthy A. Retraction: Polymer nanodiscs and macro-nanodiscs of a varying lipid composition. Chemical Communications (Cambridge, England). 54: 14033. PMID 30498816 DOI: 10.1039/c8cc90544d  1
2018 Lee YH, Lin Y, Cox SJ, Kinoshita M, Sahoo BR, Ivanova M, Ramamoorthy A. Zinc Boosts EGCG's hIAPP Amyloid Inhibition both in solution and Membrane. Biochimica Et Biophysica Acta. Proteins and Proteomics. PMID 30468883 DOI: 10.1016/j.bbapap.2018.11.006  1
2018 Sahoo BR, Genjo T, Bekier M, Cox SJ, Stoddard AK, Ivanova M, Yasuhara K, Fierke CA, Wang Y, Ramamoorthy A. Alzheimer's amyloid-beta intermediates generated using polymer-nanodiscs. Chemical Communications (Cambridge, England). PMID 30379172 DOI: 10.1039/c8cc07921h  1
2018 Sahoo BR, Genjo T, Cox SJ, Stoddard AK, Anantharamaiah GM, Fierke C, Ramamoorthy A. Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-Beta Aggregation. Journal of Molecular Biology. PMID 30170005 DOI: 10.1016/j.jmb.2018.08.018  1
2018 Ravula T, Hardin NZ, Bai J, Im SC, Waskell L, Ramamoorthy A. Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs. Chemical Communications (Cambridge, England). PMID 30094448 DOI: 10.1039/c8cc04184a  1
2018 Barnaba C, Ramamoorthy A. Picturing the Membrane-Assisted Choreography of Cytochrome P450 with Lipid-Nanodiscs. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 29995333 DOI: 10.1002/cphc.201800444  1
2018 Barnaba C, Ravula T, Medina-Meza IG, Im SC, Anantharamaiah GM, Waskell L, Ramamoorthy A. Lipid-exchange in nanodiscs discloses membrane boundaries of cytochrome-P450 reductase. Chemical Communications (Cambridge, England). PMID 29863198 DOI: 10.1039/c8cc02003e  1
2018 Damron J, Ma J, Kurz R, Saalwaechter K, Matzger A, Ramamoorthy A. The Influence of Chemical Modification on Linker Rotational Dynamics in Metal Organic Frameworks. Angewandte Chemie (International Ed. in English). PMID 29782692 DOI: 10.1002/anie.201805004  1
2018 Gentry KA, Zhang M, Im SC, Waskell L, Ramamoorthy A. Substrate mediated redox partner selectivity of cytochrome P450. Chemical Communications (Cambridge, England). PMID 29781479 DOI: 10.1039/c8cc02525h  1
2018 Rodriguez Camargo DC, Garg D, Buday K, Franko A, Rodriguez Camargo A, Schmidt F, Cox SJ, Suladze S, Haslbeck M, Mideksa YG, Gemmecker G, Aichler M, Mettenleiter G, Schulz M, Walch AK, ... ... Ramamoorthy A, et al. hIAPP forms toxic oligomers in plasma. Chemical Communications (Cambridge, England). PMID 29745410 DOI: 10.1039/c8cc03097a  1
2018 Kotler SA, Ramamoorthy A. Preparation of Stable Amyloid-β Oligomers Without Perturbative Methods. Methods in Molecular Biology (Clifton, N.J.). 1777: 331-338. PMID 29744846 DOI: 10.1007/978-1-4939-7811-3_21  1
2018 Prade E, Mahajan M, Im SC, Zhang M, Anantharamaiah GM, Waskell L, Ramamoorthy A. A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs. Angewandte Chemie (International Ed. in English). PMID 29722926 DOI: 10.1002/anie.201802210  1
2018 Terakawa MS, Lin Y, Kinoshita M, Kanemura S, Itoh D, Sugiki T, Okumura M, Ramamoorthy A, Lee YH. Impact of membrane curvature on amyloid aggregation. Biochimica Et Biophysica Acta. PMID 29709613 DOI: 10.1016/j.bbamem.2018.04.012  1
2018 Ison G, Howie LJ, Amiri-Kordestani L, Zhang L, Tang S, Sridhara R, Pierre V, Charlab R, Ramamoorthy A, Song P, Li F, Yu J, Manheng W, Palmby TR, Ghosh S, et al. FDA Approval Summary: Niraparib for the maintenance treatment of patients with recurrent ovarian cancer in response to platinum-based chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29650751 DOI: 10.1158/1078-0432.CCR-18-0042  0.36
2018 Sciacca MFM, Chillemi R, Sciuto S, Greco V, Messineo C, Kotler SA, Lee DK, Brender JR, Ramamoorthy A, La Rosa C, Milardi D. A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage. Biochimica Et Biophysica Acta. PMID 29555190 DOI: 10.1016/j.bbamem.2018.03.012  1
2018 Lee YH, Ramamoorthy A. Semen-Derived Amyloidogenic Peptides - Key Players of HIV Infection. Protein Science : a Publication of the Protein Society. PMID 29493036 DOI: 10.1002/pro.3395  1
2018 Wang J, Yamamoto T, Bai J, Cox SJ, Korshavn KJ, Monette M, Ramamoorthy A. Real-time monitoring of the aggregation of Alzheimer's amyloid-β viaH magic angle spinning NMR spectroscopy. Chemical Communications (Cambridge, England). 54: 2000-2003. PMID 29411841 DOI: 10.1039/c8cc00167g  1
2018 Barnaba C, Sahoo BR, Ravula T, Medina-Meza IG, Im SC, Anantharamaiah GM, Waskell L, Ramamoorthy A. Cytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs. Angewandte Chemie (International Ed. in English). 57: 3391-3395. PMID 29385304 DOI: 10.1002/anie.201713167  1
2018 Zhou Y, Damasceno PF, Somashekar BS, Engel M, Tian F, Zhu J, Huang R, Johnson K, McIntyre C, Sun K, Yang M, Green PF, Ramamoorthy A, Glotzer SC, Kotov NA. Unusual multiscale mechanics of biomimetic nanoparticle hydrogels. Nature Communications. 9: 181. PMID 29330415 DOI: 10.1038/s41467-017-02579-w  1
2018 Ravula T, Hardin NZ, Ramadugu SK, Cox SJ, Ramamoorthy A. Formation of pH-Resistant Monodispersed Polymer-Lipid Nanodiscs. Angewandte Chemie (International Ed. in English). 57: 1342-1345. PMID 29232017 DOI: 10.1002/anie.201712017  1
2017 Yasuhara K, Arakida J, Ravula T, Ramadugu SK, Sahoo B, Kikuchi JI, Ramamoorthy A. Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers. Journal of the American Chemical Society. 139: 18657-18663. PMID 29171274 DOI: 10.1021/jacs.7b10591  1
2017 Rodriguez Camargo DC, Korshavn KJ, Jussupow A, Raltchev K, Goricanec D, Fleisch M, Sarkar R, Xue K, Aichler M, Mettenleiter G, Walch AK, Camilloni C, Hagn F, Reif B, Ramamoorthy A. Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate. Elife. 6. PMID 29148426 DOI: 10.7554/eLife.31226  1
2017 Ravula T, Barnaba C, Mahajan M, Anantharamaiah GM, Im SC, Waskell L, Ramamoorthy A. Membrane environment drives cytochrome P450's spin transition and its interaction with cytochrome b. Chemical Communications (Cambridge, England). 53: 12798-12801. PMID 29143058 DOI: 10.1039/c7cc07520k  1
2017 Beck MW, Derrick JS, Suh JM, Kim M, Korshavn KJ, Kerr RA, Cho WJ, Larsen SD, Ruotolo BT, Ramamoorthy A, Lim MH. Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease. Chemmedchem. 12: 1828-1838. PMID 28990338 DOI: 10.1002/cmdc.201700456  1
2017 Jones MR, Mathieu E, Dyrager C, Faissner S, Vaillancourt Z, Korshavn KJ, Lim MH, Ramamoorthy A, Wee Yong V, Tsutsui S, Stys PK, Storr T. Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease. Chemical Science. 8: 5636-5643. PMID 28989601 DOI: 10.1039/c7sc01269a  1
2017 Ramadugu VSK, Di Mauro GM, Ravula T, Ramamoorthy A. Polymer nanodiscs and macro-nanodiscs of a varying lipid composition. Chemical Communications (Cambridge, England). 53: 10824-10826. PMID 28926036 DOI: 10.1039/c7cc06409h  1
2017 Ravula T, Hardin NZ, Ramadugu SK, Ramamoorthy A. pH Tunable and Divalent Metal Ion Tolerant Polymer Lipid Nanodiscs. Langmuir : the Acs Journal of Surfaces and Colloids. 33: 10655-10662. PMID 28920693 DOI: 10.1021/acs.langmuir.7b02887  1
2017 Damron JT, Kersten K, Pandey MK, Mroue KH, Reddy J, Nishiyama Y, Matzger AJ, Ramamoorthy A. Electrostatic Constraints Assessed by 1H MAS NMR Illuminate Differences in Crystalline Polymorphs. The Journal of Physical Chemistry Letters. PMID 28825828 DOI: 10.1021/acs.jpclett.7b01650  1
2017 Gentry KA, Prade E, Barnaba C, Zhang M, Mahajan M, Im SC, Anantharamaiah GM, Nagao S, Waskell L, Ramamoorthy A. Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome band Cytochrome c. Scientific Reports. 7: 7793. PMID 28798301 DOI: 10.1038/s41598-017-08130-7  1
2017 Kamgar-Parsi K, Hong L, Naito A, Brooks CL, Ramamoorthy A. Growth-incompetent monomers of human calcitonin lead to a non-canonical direct relationship between peptide concentration and lag time. The Journal of Biological Chemistry. PMID 28739873 DOI: 10.1074/jbc.M117.791236  1
2017 Ravula T, Ramadugu SK, Di Mauro G, Ramamoorthy A. Bioinspired, Size-Tunable Self-Assembly of Polymer-Lipid Bilayer Nanodiscs. Angewandte Chemie (International Ed. in English). 56: 11466-11470. PMID 28714233 DOI: 10.1002/anie.201705569  1
2017 Mukherjee S, Kar RK, Nanga RPR, Mroue KH, Ramamoorthy A, Bhunia A. Accelerated molecular dynamics simulation analysis of MSI-594 in a lipid bilayer. Physical Chemistry Chemical Physics : Pccp. 19: 19289-19299. PMID 28702543 DOI: 10.1039/c7cp01941f  1
2017 Yamamoto K, Caporini MA, Im SC, Waskell L, Ramamoorthy A. Transmembrane Interactions of Full-length Mammalian Bitopic Cytochrome-P450-Cytochrome-bComplex in Lipid Bilayers Revealed by Sensitivity-Enhanced Dynamic Nuclear Polarization Solid-state NMR Spectroscopy. Scientific Reports. 7: 4116. PMID 28646173 DOI: 10.1038/s41598-017-04219-1  1
2017 Kinoshita M, Kakimoto E, Terakawa MS, Lin Y, Ikenoue T, So M, Sugiki T, Ramamoorthy A, Goto Y, Lee YH. Model membrane size-dependent amyloidogenesis of Alzheimer's amyloid-β peptides. Physical Chemistry Chemical Physics : Pccp. PMID 28608875 DOI: 10.1039/c6cp07774a  1
2017 Naito A, Matsumori N, Ramamoorthy A. Dynamic membrane interactions of antibacterial and antifungal biomolecules, and amyloid peptides, revealed by solid-state NMR spectroscopy. Biochimica Et Biophysica Acta. PMID 28599848 DOI: 10.1016/j.bbagen.2017.06.004  1
2017 Zhang R, Duong NT, Nishiyama Y, Ramamoorthy A. 3D Double-Quantum/Double-Quantum Exchange Spectroscopy of Protons under 100 kHz Magic Angle Spinning. The Journal of Physical Chemistry. B. 121: 5944-5952. PMID 28537394 DOI: 10.1021/acs.jpcb.7b03480  1
2017 Barnaba C, Gentry K, Sumangala N, Ramamoorthy A. The catalytic function of cytochrome P450 is entwined with its membrane-bound nature. F1000research. 6: 662. PMID 28529725 DOI: 10.12688/f1000research.11015.1  1
2017 Tian D, Li T, Zhang R, Wu Q, Chen T, Sun P, Ramamoorthy A. Conformations and Intermolecular Interactions in Cellulose/Silk Fibroin Blend Films: A Solid-State NMR Perspective. The Journal of Physical Chemistry. B. 121: 6108-6116. PMID 28481526 DOI: 10.1021/acs.jpcb.7b02838  1
2017 Zhang R, Mroue KH, Ramamoorthy A. Proton-Based Ultrafast Magic Angle Spinning Solid-State NMR Spectroscopy. Accounts of Chemical Research. 50: 1105-1113. PMID 28353338 DOI: 10.1021/acs.accounts.7b00082  1
2017 Korshavn KJ, Satriano C, Lin Y, Zhang R, Dulchavsky M, Bhunia A, Ivanova MI, Lee YH, La Rosa C, Lim MH, Ramamoorthy A. Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β. The Journal of Biological Chemistry. 292: 4638-4650. PMID 28154182 DOI: 10.1074/jbc.M116.764092  1
2017 Lee HJ, Korshavn KJ, Nam Y, Kang J, Paul TJ, Kerr RA, Youn IS, Ozbil M, Kim KS, Ruotolo BT, Prabhakar R, Ramamoorthy A, Lim MH. Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 2706-2715. PMID 28004889 DOI: 10.1002/chem.201605401  1
2017 Kang J, Lee SJ, Nam JS, Lee HJ, Kang MG, Korshavn KJ, Kim HT, Cho J, Ramamoorthy A, Rhee HW, Kwon TH, Lim MH. An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 1645-1653. PMID 27862428 DOI: 10.1002/chem.201604751  1
2016 Datta A, Yadav V, Ghosh A, Choi J, Bhattacharyya D, Kar RK, Ilyas H, Dutta A, An E, Mukhopadhyay J, Lee D, Sanyal K, Ramamoorthy A, Bhunia A. Mode of Action of a Designed Antimicrobial Peptide: High Potency against Cryptococcus neoformans. Biophysical Journal. 111: 1724-1737. PMID 27760359 DOI: 10.1016/j.bpj.2016.08.032  1
2016 Sciacca MF, Lolicato F, Di Mauro G, Milardi D, D'Urso L, Satriano C, Ramamoorthy A, La Rosa C. The Role of Cholesterol in Driving IAPP-Membrane Interactions. Biophysical Journal. 111: 140-51. PMID 27410742 DOI: 10.1016/j.bpj.2016.05.050  1
2016 Mroue KH, Xu J, Zhu P, Morris MD, Ramamoorthy A. Selective detection and complete identification of triglycerides in cortical bone by high-resolution (1)H MAS NMR spectroscopy. Physical Chemistry Chemical Physics : Pccp. 18: 18687-91. PMID 27374353 DOI: 10.1039/c6cp03506j  1
2016 Zhang R, Chen Y, Rodriguez-Hornedo N, Ramamoorthy A. Enhancing NMR Sensitivity of Natural-Abundance Low-γ Nuclei by Ultrafast Magic-Angle-Spinning Solid-State NMR Spectroscopy. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 17: 2962-2966. PMID 27310287 DOI: 10.1002/cphc.201600637  1
2016 Bera S, Korshavn KJ, Kar RK, Lim MH, Ramamoorthy A, Bhunia A. Biophysical insights into the membrane interaction of the core amyloid-forming Aβ40 fragment K16-K28 and its role in the pathogenesis of Alzheimer's disease. Physical Chemistry Chemical Physics : Pccp. 18: 16890-901. PMID 27282693 DOI: 10.1039/c6cp02023b  1
2016 Jones MR, Dyrager C, Hoarau M, Korshavn KJ, Lim MH, Ramamoorthy A, Storr T. Multifunctional quinoline-triazole derivatives as potential modulators of amyloid-β peptide aggregation. Journal of Inorganic Biochemistry. 158: 131-138. PMID 27133802 DOI: 10.1016/j.jinorgbio.2016.04.022  1
2016 Derrick JS, Kerr RA, Korshavn KJ, McLane MJ, Kang J, Nam E, Ramamoorthy A, Ruotolo BT, Lim MH. Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-β, and Oxidative Stress in Alzheimer's Disease. Inorganic Chemistry. 55: 5000-13. PMID 27119456 DOI: 10.1021/acs.inorgchem.6b00525  1
2016 Zhang R, Mroue KH, Ramamoorthy A. Hybridizing cross-polarization with NOE or refocused-INEPT enhances the sensitivity of MAS NMR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 266: 59-66. PMID 27040936 DOI: 10.1016/j.jmr.2016.03.006  1
2016 Pandey MK, Yarava JR, Zhang R, Ramamoorthy A, Nishiyama Y. Proton-detected 3D (15)N/(1)H/(1)H isotropic/anisotropic/isotropic chemical shift correlation solid-state NMR at 70kHz MAS. Solid State Nuclear Magnetic Resonance. 76: 1-6. PMID 27017575 DOI: 10.1016/j.ssnmr.2016.03.001  1
2016 Fichman G, Guterman T, Damron J, Adler-Abramovich L, Schmidt J, Kesselman E, Shimon LJ, Ramamoorthy A, Talmon Y, Gazit E. Spontaneous structural transition and crystal formation in minimal supramolecular polymer model. Science Advances. 2: e1500827. PMID 26933679 DOI: 10.1126/sciadv.1500827  1
2016 Zhang M, Huang R, Ackermann R, Im SC, Waskell L, Schwendeman A, Ramamoorthy A. Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy. Angewandte Chemie (International Ed. in English). 55: 4497-9. PMID 26924779 DOI: 10.1002/anie.201600073  1
2016 Zhang R, Ramamoorthy A. Constant-time 2D and 3D through-bond correlation NMR spectroscopy of solids under 60 kHz MAS. The Journal of Chemical Physics. 144: 034202. PMID 26801026 DOI: 10.1063/1.4940029  1
2016 Pithadia A, Brender JR, Fierke CA, Ramamoorthy A. Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives. Journal of Diabetes Research. 2016: 2046327. PMID 26649317 DOI: 10.1155/2016/2046327  1
2016 Pithadia AS, Bhunia A, Sribalan R, Padmini V, Fierke CA, Ramamoorthy A. Influence of a curcumin derivative on hIAPP aggregation in the absence and presence of lipid membranes. Chemical Communications (Cambridge, England). 52: 942-5. PMID 26587568 DOI: 10.1039/c5cc07792c  1
2016 Korshavn KJ, Bhunia A, Lim MH, Ramamoorthy A. Amyloid-β adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation. Chemical Communications (Cambridge, England). 52: 882-5. PMID 26553596 DOI: 10.1039/c5cc08634e  1
2015 Korshavn KJ, Jang M, Kwak YJ, Kochi A, Vertuani S, Bhunia A, Manfredini S, Ramamoorthy A, Lim MH. Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives. Scientific Reports. 5: 17842. PMID 26657338 DOI: 10.1038/srep17842  1
2015 Derrick JS, Kerr RA, Nam Y, Oh SB, Lee HJ, Earnest KG, Suh N, Peck KL, Ozbil M, Korshavn KJ, Ramamoorthy A, Prabhakar R, Merino EJ, Shearer J, Lee JY, et al. A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms. Journal of the American Chemical Society. 137: 14785-97. PMID 26575890 DOI: 10.1021/jacs.5b10043  1
2015 Pandey MK, Zhang R, Hashi K, Ohki S, Nishijima G, Matsumoto S, Noguchi T, Deguchi K, Goto A, Shimizu T, Maeda H, Takahashi M, Yanagisawa Y, Yamazaki T, Iguchi S, ... ... Ramamoorthy A, et al. 1020MHz single-channel proton fast magic angle spinning solid-state NMR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 261: 1-5. PMID 26524647 DOI: 10.1016/j.jmr.2015.10.003  1
2015 Zhang R, Nishiyama Y, Ramamoorthy A. Proton-detected 3D (1)H/(13)C/(1)H correlation experiment for structural analysis in rigid solids under ultrafast-MAS above 60 kHz. The Journal of Chemical Physics. 143: 164201. PMID 26520504 DOI: 10.1063/1.4933373  1
2015 Zhang R, Mroue KH, Ramamoorthy A. Proton chemical shift tensors determined by 3D ultrafast MAS double-quantum NMR spectroscopy. The Journal of Chemical Physics. 143: 144201. PMID 26472372 DOI: 10.1063/1.4933114  1
2015 Zhang R, Ramamoorthy A. Selective excitation enables assignment of proton resonances and (1)H-(1)H distance measurement in ultrafast magic angle spinning solid state NMR spectroscopy. The Journal of Chemical Physics. 143: 034201. PMID 26203019 DOI: 10.1063/1.4926834  1
2015 Mroue KH, Nishiyama Y, Kumar Pandey M, Gong B, McNerny E, Kohn DH, Morris MD, Ramamoorthy A. Proton-Detected Solid-State NMR Spectroscopy of Bone with Ultrafast Magic Angle Spinning. Scientific Reports. 5: 11991. PMID 26153138 DOI: 10.1038/srep11991  1
2015 Datta A, Ghosh A, Airoldi C, Sperandeo P, Mroue KH, Jiménez-Barbero J, Kundu P, Ramamoorthy A, Bhunia A. Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control. Scientific Reports. 5: 11951. PMID 26144972 DOI: 10.1038/srep11951  1
2015 Kotler SA, Brender JR, Vivekanandan S, Suzuki Y, Yamamoto K, Monette M, Krishnamoorthy J, Walsh P, Cauble M, Holl MM, Marsh EN, Ramamoorthy A. High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification. Scientific Reports. 5: 11811. PMID 26138908 DOI: 10.1038/srep11811  1
2015 Zhang R, Pandey MK, Nishiyama Y, Ramamoorthy A. A Novel High-Resolution and Sensitivity-Enhanced Three-Dimensional Solid-State NMR Experiment Under Ultrafast Magic Angle Spinning Conditions. Scientific Reports. 5: 11810. PMID 26138791 DOI: 10.1038/srep11810  1
2015 Kamarajan P, Hayami T, Matte B, Liu Y, Danciu T, Ramamoorthy A, Worden F, Kapila S, Kapila Y. Nisin ZP, a Bacteriocin and Food Preservative, Inhibits Head and Neck Cancer Tumorigenesis and Prolongs Survival. Plos One. 10: e0131008. PMID 26132406 DOI: 10.1371/journal.pone.0131008  1
2015 Zhang R, Ramamoorthy A. Dynamics-based selective 2D (1)H/(1)H chemical shift correlation spectroscopy under ultrafast MAS conditions. The Journal of Chemical Physics. 142: 204201. PMID 26026440 DOI: 10.1063/1.4921381  1
2015 Zhang M, Huang R, Im SC, Waskell L, Ramamoorthy A. Effects of membrane mimetics on cytochrome P450-cytochrome b5 interactions characterized by NMR spectroscopy. The Journal of Biological Chemistry. 290: 12705-18. PMID 25795780 DOI: 10.1074/jbc.M114.597096  1
2015 Ghosh A, Pithadia AS, Bhat J, Bera S, Midya A, Fierke CA, Ramamoorthy A, Bhunia A. Self-assembly of a nine-residue amyloid-forming peptide fragment of SARS corona virus E-protein: mechanism of self aggregation and amyloid-inhibition of hIAPP. Biochemistry. 54: 2249-2261. PMID 25785896 DOI: 10.1021/acs.biochem.5b00061  1
2015 Lee DK, Bhunia A, Kotler SA, Ramamoorthy A. Detergent-type membrane fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 antimicrobial peptides and inhibition by cholesterol: a solid-state nuclear magnetic resonance study. Biochemistry. 54: 1897-907. PMID 25715195 DOI: 10.1021/bi501418m  1
2015 Soblosky L, Ramamoorthy A, Chen Z. Membrane interaction of antimicrobial peptides using E. coli lipid extract as model bacterial cell membranes and SFG spectroscopy. Chemistry and Physics of Lipids. 187: 20-33. PMID 25707312 DOI: 10.1016/j.chemphyslip.2015.02.003  1
2015 Zhang M, Le Clair SV, Huang R, Ahuja S, Im SC, Waskell L, Ramamoorthy A. Insights into the role of substrates on the interaction between cytochrome b5 and cytochrome P450 2B4 by NMR. Scientific Reports. 5: 8392. PMID 25687717 DOI: 10.1038/srep08392  1
2015 Zhang R, Nishiyama Y, Sun P, Ramamoorthy A. Phase cycling schemes for finite-pulse-RFDR MAS solid state NMR experiments. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 252: 55-66. PMID 25655451 DOI: 10.1016/j.jmr.2014.12.010  1
2015 Brender JR, Krishnamoorthy J, Sciacca MF, Vivekanandan S, D'Urso L, Chen J, La Rosa C, Ramamoorthy A. Probing the sources of the apparent irreproducibility of amyloid formation: drastic changes in kinetics and a switch in mechanism due to micellelike oligomer formation at critical concentrations of IAPP. The Journal of Physical Chemistry. B. 119: 2886-96. PMID 25645610 DOI: 10.1021/jp511758w  1
2015 Chattah AK, Zhang R, Mroue KH, Pfund LY, Longhi MR, Ramamoorthy A, Garnero C. Investigating albendazole desmotropes by solid-state NMR spectroscopy. Molecular Pharmaceutics. 12: 731-41. PMID 25584993 DOI: 10.1021/mp500539g  1
2015 Yamamoto K, Pearcy P, Lee DK, Yu C, Im SC, Waskell L, Ramamoorthy A. Temperature-resistant bicelles for structural studies by solid-state NMR spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 1496-504. PMID 25565453 DOI: 10.1021/la5043876  1
2015 Huang R, Zhang M, Rwere F, Waskell L, Ramamoorthy A. Kinetic and structural characterization of the interaction between the FMN binding domain of cytochrome P450 reductase and cytochrome c. The Journal of Biological Chemistry. 290: 4843-55. PMID 25512382 DOI: 10.1074/jbc.M114.582700  1
2015 Pandey MK, Malon M, Ramamoorthy A, Nishiyama Y. Composite-180° pulse-based symmetry sequences to recouple proton chemical shift anisotropy tensors under ultrafast MAS solid-state NMR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 250: 45-54. PMID 25497846 DOI: 10.1016/j.jmr.2014.11.002  1
2015 Zhang R, Damron J, Vosegaard T, Ramamoorthy A. A cross-polarization based rotating-frame separated-local-field NMR experiment under ultrafast MAS conditions. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 250: 37-44. PMID 25486635 DOI: 10.1016/j.jmr.2014.10.013  1
2015 Sudheendra US, Dhople V, Datta A, Kar RK, Shelburne CE, Bhunia A, Ramamoorthy A. Membrane disruptive antimicrobial activities of human β-defensin-3 analogs. European Journal of Medicinal Chemistry. 91: 91-9. PMID 25112689 DOI: 10.1016/j.ejmech.2014.08.021  1
2015 Yamamoto K, Caporini MA, Im SC, Waskell L, Ramamoorthy A. Cellular solid-state NMR investigation of a membrane protein using dynamic nuclear polarization. Biochimica Et Biophysica Acta. 1848: 342-9. PMID 25017802 DOI: 10.1016/j.bbamem.2014.07.008  1
2014 Patel HR, Pithadia AS, Brender JR, Fierke CA, Ramamoorthy A. In Search of Aggregation Pathways of IAPP and Other Amyloidogenic Proteins: Finding Answers through NMR Spectroscopy. The Journal of Physical Chemistry Letters. 5: 1864-70. PMID 26273866 DOI: 10.1021/jz5001775  1
2014 DeToma AS, Krishnamoorthy J, Nam Y, Lee HJ, Brender JR, Kochi A, Lee D, Onnis V, Congiu C, Manfredini S, Vertuani S, Balboni G, Ramamoorthy A, Lim MH. Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species. Chemical Science. 5: 4851-4862. PMID 25383163 DOI: 10.1039/c4sc01531b  1
2014 Mroue KH, Zhang R, Zhu P, McNerny E, Kohn DH, Morris MD, Ramamoorthy A. Acceleration of natural-abundance solid-state MAS NMR measurements on bone by paramagnetic relaxation from gadolinium-DTPA. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 244: 90-7. PMID 24881032 DOI: 10.1016/j.jmr.2014.04.020  1
2014 Huang R, Yamamoto K, Zhang M, Popovych N, Hung I, Im SC, Gan Z, Waskell L, Ramamoorthy A. Probing the transmembrane structure and dynamics of microsomal NADPH-cytochrome P450 oxidoreductase by solid-state NMR. Biophysical Journal. 106: 2126-33. PMID 24853741 DOI: 10.1016/j.bpj.2014.03.051  1
2014 Nishiyama Y, Malon M, Ishii Y, Ramamoorthy A. 3D ¹⁵N/¹⁵N/¹H chemical shift correlation experiment utilizing an RFDR-based ¹H/¹H mixing period at 100 kHz MAS. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 244: 1-5. PMID 24801998 DOI: 10.1016/j.jmr.2014.04.008  1
2014 Zhang R, Ramamoorthy A. Performance of RINEPT is amplified by dipolar couplings under ultrafast MAS conditions. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 243: 85-92. PMID 24792960 DOI: 10.1016/j.jmr.2014.03.012  1
2014 Yesuvadian R, Krishnamoorthy J, Ramamoorthy A, Bhunia A. Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: a high-resolution NMR study. Biochemical and Biophysical Research Communications. 447: 590-5. PMID 24747079 DOI: 10.1016/j.bbrc.2014.04.041  1
2014 Nishiyama Y, Zhang R, Ramamoorthy A. Finite-pulse radio frequency driven recoupling with phase cycling for 2D (1)H/(1)H correlation at ultrafast MAS frequencies. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 243: 25-32. PMID 24713171 DOI: 10.1016/j.jmr.2014.03.004  1
2014 Pandey MK, Vivekanandan S, Yamamoto K, Im S, Waskell L, Ramamoorthy A. Proton-detected 2D radio frequency driven recoupling solid-state NMR studies on micelle-associated cytochrome-b(5). Journal of Magnetic Resonance (San Diego, Calif. : 1997). 242: 169-79. PMID 24657390 DOI: 10.1016/j.jmr.2014.02.016  1
2014 Kotler SA, Walsh P, Brender JR, Ramamoorthy A. Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease. Chemical Society Reviews. 43: 6692-700. PMID 24464312 DOI: 10.1039/c3cs60431d  1
2014 Yamamoto K, Pearcy P, Ramamoorthy A. Bicelles exhibiting magnetic alignment for a broader range of temperatures: a solid-state NMR study. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 1622-9. PMID 24460179 DOI: 10.1021/la404331t  1
2014 Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH. Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. Journal of the American Chemical Society. 136: 299-310. PMID 24397771 DOI: 10.1021/ja409801p  1
2014 Tsukamoto M, Kuroda K, Ramamoorthy A, Yasuhara K. Modulation of raft domains in a lipid bilayer by boundary-active curcumin. Chemical Communications (Cambridge, England). 50: 3427-30. PMID 24396862 DOI: 10.1039/c3cc47738j  1
2014 Zhao J, Hu R, Sciacca MF, Brender JR, Chen H, Ramamoorthy A, Zheng J. Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels. Physical Chemistry Chemical Physics : Pccp. 16: 2368-77. PMID 24352606 DOI: 10.1039/c3cp53345j  1
2014 Savelieff MG, Liu Y, Senthamarai RR, Korshavn KJ, Lee HJ, Ramamoorthy A, Lim MH. A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease. Chemical Communications (Cambridge, England). 50: 5301-3. PMID 24326305 DOI: 10.1039/c3cc48473d  1
2014 Higashi K, Yamamoto K, Pandey MK, Mroue KH, Moribe K, Yamamoto K, Ramamoorthy A. Insights into atomic-level interaction between mefenamic acid and eudragit EPO in a supersaturated solution by high-resolution magic-angle spinning NMR spectroscopy. Molecular Pharmaceutics. 11: 351-7. PMID 24283196 DOI: 10.1021/mp4005723  1
2014 Vivekanandan S, Ahuja S, Im SC, Waskell L, Ramamoorthy A. ¹H, ¹³C and ¹⁵N resonance assignments for the full-length mammalian cytochrome b₅ in a membrane environment. Biomolecular Nmr Assignments. 8: 409-13. PMID 24105099 DOI: 10.1007/s12104-013-9528-9  1
2013 McElderry JD, Zhu P, Mroue KH, Xu J, Pavan B, Fang M, Zhao G, McNerny E, Kohn DH, Franceschi RT, Holl MM, Tecklenburg MM, Ramamoorthy A, Morris MD. Crystallinity and compositional changes in carbonated apatites: Evidence fromP solid-state NMR, Raman, and AFM analysis. Journal of Solid State Chemistry. 206. PMID 24273344 DOI: 10.1016/j.jssc.2013.08.011  1
2013 Yamamoto K, Caporini MA, Im S, Waskell L, Ramamoorthy A. Shortening spin-lattice relaxation using a copper-chelated lipid at low-temperatures - A magic angle spinning solid-state NMR study on a membrane-bound protein. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 237: 175-81. PMID 24246881 DOI: 10.1016/j.jmr.2013.10.017  1
2013 Pandey MK, Vivekanandan S, Ahuja S, Huang R, Im SC, Waskell L, Ramamoorthy A. Cytochrome-P450-cytochrome-b5 interaction in a membrane environment changes 15N chemical shift anisotropy tensors. The Journal of Physical Chemistry. B. 117: 13851-60. PMID 24107224 DOI: 10.1021/jp4086206  1
2013 Yamamoto K, Gildenberg M, Ahuja S, Im SC, Pearcy P, Waskell L, Ramamoorthy A. Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles. Scientific Reports. 3: 2556. PMID 23989972 DOI: 10.1038/srep02556  1
2013 Yamamoto K, Dürr UH, Xu J, Im SC, Waskell L, Ramamoorthy A. Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy. Scientific Reports. 3: 2538. PMID 23985776 DOI: 10.1038/srep02538  1
2013 Porcelli F, Ramamoorthy A, Barany G, Veglia G. On the role of NMR spectroscopy for characterization of antimicrobial peptides. Methods in Molecular Biology (Clifton, N.J.). 1063: 159-80. PMID 23975777 DOI: 10.1007/978-1-62703-583-5_9  1
2013 Chattah AK, Mroue KH, Pfund LY, Ramamoorthy A, Longhi MR, Garnero C. insights into novel supramolecular complexes of two solid forms of norfloxacin and β-cyclodextrin. Journal of Pharmaceutical Sciences. 102: 3717-24. PMID 23904189 DOI: 10.1002/jps.23683  1
2013 Ramamoorthy A, Lim MH. Structural characterization and inhibition of toxic amyloid-β oligomeric intermediates. Biophysical Journal. 105: 287-8. PMID 23870249 DOI: 10.1016/j.bpj.2013.05.004  1
2013 Tripathi P, Somashekar BS, Ponnusamy M, Gursky A, Dailey S, Kunju P, Lee CT, Chinnaiyan AM, Rajendiran TM, Ramamoorthy A. HR-MAS NMR tissue metabolomic signatures cross-validated by mass spectrometry distinguish bladder cancer from benign disease. Journal of Proteome Research. 12: 3519-28. PMID 23731241 DOI: 10.1021/pr4004135  1
2013 Ahuja S, Jahr N, Im SC, Vivekanandan S, Popovych N, Le Clair SV, Huang R, Soong R, Xu J, Yamamoto K, Nanga RP, Bridges A, Waskell L, Ramamoorthy A. A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. The Journal of Biological Chemistry. 288: 22080-95. PMID 23709268 DOI: 10.1074/jbc.M112.448225  1
2013 Ding B, Soblosky L, Nguyen K, Geng J, Yu X, Ramamoorthy A, Chen Z. Physiologically-relevant modes of membrane interactions by the human antimicrobial peptide, LL-37, revealed by SFG experiments. Scientific Reports. 3: 1854. PMID 23676762 DOI: 10.1038/srep01854  1
2013 Ramamoorthy A. Insights into protein misfolding and amyloidogenesis. Physical Chemistry Chemical Physics : Pccp. 15: 8867. PMID 23673429 DOI: 10.1039/c3cp90062b  1
2013 Ramamoorthy A, Xu J. 2D 1H/1H RFDR and NOESY NMR experiments on a membrane-bound antimicrobial peptide under magic angle spinning. The Journal of Physical Chemistry. B. 117: 6693-700. PMID 23672643 DOI: 10.1021/jp4034003  1
2013 Hartman K, Brender JR, Monde K, Ono A, Evans ML, Popovych N, Chapman MR, Ramamoorthy A. Bacterial curli protein promotes the conversion of PAP248-286 into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences. Peerj. 1: e5. PMID 23638387 DOI: 10.7717/peerj.5  1
2013 Lee DK, Brender JR, Sciacca MF, Krishnamoorthy J, Yu C, Ramamoorthy A. Lipid composition-dependent membrane fragmentation and pore-forming mechanisms of membrane disruption by pexiganan (MSI-78). Biochemistry. 52: 3254-63. PMID 23590672 DOI: 10.1021/bi400087n  1
2013 Brender JR, Krishnamoorthy J, Messina GM, Deb A, Vivekanandan S, La Rosa C, Penner-Hahn JE, Ramamoorthy A. Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide. Chemical Communications (Cambridge, England). 49: 3339-41. PMID 23505632 DOI: 10.1039/c3cc40383a  1
2013 Brender JR, Heyl DL, Samisetti S, Kotler SA, Osborne JM, Pesaru RR, Ramamoorthy A. Membrane disordering is not sufficient for membrane permeabilization by islet amyloid polypeptide: studies of IAPP(20-29) fragments. Physical Chemistry Chemical Physics : Pccp. 15: 8908-15. PMID 23493863 DOI: 10.1039/c3cp44696d  1
2013 Dürr UH, Soong R, Ramamoorthy A. When detergent meets bilayer: birth and coming of age of lipid bicelles. Progress in Nuclear Magnetic Resonance Spectroscopy. 69: 1-22. PMID 23465641 DOI: 10.1016/j.pnmrs.2013.01.001  1
2013 Suzuki Y, Brender JR, Soper MT, Krishnamoorthy J, Zhou Y, Ruotolo BT, Kotov NA, Ramamoorthy A, Marsh EN. Resolution of oligomeric species during the aggregation of Aβ1-40 using (19)F NMR. Biochemistry. 52: 1903-12. PMID 23445400 DOI: 10.1021/bi400027y  1
2013 Hyung SJ, DeToma AS, Brender JR, Lee S, Vivekanandan S, Kochi A, Choi JS, Ramamoorthy A, Ruotolo BT, Lim MH. Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species. Proceedings of the National Academy of Sciences of the United States of America. 110: 3743-8. PMID 23426629 DOI: 10.1073/pnas.1220326110  1
2013 Sciacca MF, Milardi D, Messina GM, Marletta G, Brender JR, Ramamoorthy A, La Rosa C. Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP. Biophysical Journal. 104: 173-84. PMID 23332070 DOI: 10.1016/j.bpj.2012.11.3811  1
2013 Pandey MK, Ramamoorthy A. Quantum chemical calculations of amide-15N chemical shift anisotropy tensors for a membrane-bound cytochrome-b5. The Journal of Physical Chemistry. B. 117: 859-67. PMID 23268659 DOI: 10.1021/jp311116p  1
2013 MacKinnon N, Somashekar BS, Tripathi P, Ge W, Rajendiran TM, Chinnaiyan AM, Ramamoorthy A. MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 226: 93-9. PMID 23232331 DOI: 10.1016/j.jmr.2012.11.008  1
2012 Krishnamoorthy J, Brender JR, Vivekanandan S, Jahr N, Ramamoorthy A. Side-chain dynamics reveals transient association of Aβ(1-40) monomers with amyloid fibers. The Journal of Physical Chemistry. B. 116: 13618-23. PMID 23116141 DOI: 10.1021/jp305279w  1
2012 Suzuki Y, Brender JR, Hartman K, Ramamoorthy A, Marsh EN. Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption. Biochemistry. 51: 8154-62. PMID 22998665 DOI: 10.1021/bi3012548  1
2012 Sciacca MF, Brender JR, Lee DK, Ramamoorthy A. Phosphatidylethanolamine enhances amyloid fiber-dependent membrane fragmentation. Biochemistry. 51: 7676-84. PMID 22970795 DOI: 10.1021/bi3009888  1
2012 Mroue KH, MacKinnon N, Xu J, Zhu P, McNerny E, Kohn DH, Morris MD, Ramamoorthy A. High-resolution structural insights into bone: a solid-state NMR relaxation study utilizing paramagnetic doping. The Journal of Physical Chemistry. B. 116: 11656-61. PMID 22953757 DOI: 10.1021/jp307935g  1
2012 Sciacca MF, Kotler SA, Brender JR, Chen J, Lee DK, Ramamoorthy A. Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation. Biophysical Journal. 103: 702-10. PMID 22947931 DOI: 10.1016/j.bpj.2012.06.045  1
2012 Dürr UH, Gildenberg M, Ramamoorthy A. The magic of bicelles lights up membrane protein structure. Chemical Reviews. 112: 6054-74. PMID 22920148 DOI: 10.1021/cr300061w  1
2012 McHenry AJ, Sciacca MF, Brender JR, Ramamoorthy A. Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes? Biochimica Et Biophysica Acta. 1818: 3019-24. PMID 22885355 DOI: 10.1016/j.bbamem.2012.07.021  1
2012 Somashekar BS, Amin AG, Tripathi P, MacKinnon N, Rithner CD, Shanley CA, Basaraba R, Henao-Tamayo M, Kato-Maeda M, Ramamoorthy A, Orme IM, Ordway DJ, Chatterjee D. Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. Journal of Proteome Research. 11: 4873-84. PMID 22873951 DOI: 10.1021/pr300345x  1
2012 Zhu J, Andres CM, Xu J, Ramamoorthy A, Tsotsis T, Kotov NA. Pseudonegative thermal expansion and the state of water in graphene oxide layered assemblies. Acs Nano. 6: 8357-65. PMID 22861527 DOI: 10.1021/nn3031244  1
2012 Jones MR, Service EL, Thompson JR, Wang MC, Kimsey IJ, DeToma AS, Ramamoorthy A, Lim MH, Storr T. Dual-function triazole-pyridine derivatives as inhibitors of metal-induced amyloid-β aggregation. Metallomics : Integrated Biometal Science. 4: 910-20. PMID 22825244 DOI: 10.1039/c2mt20113e  1
2012 Brender JR, McHenry AJ, Ramamoorthy A. Does cholesterol play a role in the bacterial selectivity of antimicrobial peptides? Frontiers in Immunology. 3: 195. PMID 22822405 DOI: 10.3389/fimmu.2012.00195  1
2012 Tripathi P, Kamarajan P, Somashekar BS, MacKinnon N, Chinnaiyan AM, Kapila YL, Rajendiran TM, Ramamoorthy A. Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target. The International Journal of Biochemistry & Cell Biology. 44: 1852-61. PMID 22743333 DOI: 10.1016/j.biocel.2012.06.025  1
2012 Khitrin AK, Xu J, Ramamoorthy A. Coherent averaging in the frequency domain. The Journal of Chemical Physics. 136: 214504. PMID 22697555 DOI: 10.1063/1.4723682  1
2012 Pandey MK, Vivekanandan S, Ahuja S, Pichumani K, Im SC, Waskell L, Ramamoorthy A. Determination of 15N chemical shift anisotropy from a membrane-bound protein by NMR spectroscopy. The Journal of Physical Chemistry. B. 116: 7181-9. PMID 22620865 DOI: 10.1021/jp3049229  1
2012 MacKinnon N, Ge W, Khan AP, Somashekar BS, Tripathi P, Siddiqui J, Wei JT, Chinnaiyan AM, Rajendiran TM, Ramamoorthy A. Variable reference alignment: an improved peak alignment protocol for NMR spectral data with large intersample variation. Analytical Chemistry. 84: 5372-9. PMID 22616856 DOI: 10.1021/ac301327k  1
2012 Popovych N, Brender JR, Soong R, Vivekanandan S, Hartman K, Basrur V, Macdonald PM, Ramamoorthy A. Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286). The Journal of Physical Chemistry. B. 116: 3650-8. PMID 22360607 DOI: 10.1021/jp2121577  1
2012 Huang R, Vivekanandan S, Brender JR, Abe Y, Naito A, Ramamoorthy A. NMR characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with EGCG. Journal of Molecular Biology. 416: 108-20. PMID 22200484 DOI: 10.1016/j.jmb.2011.12.023  1
2012 Brender JR, Salamekh S, Ramamoorthy A. Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective. Accounts of Chemical Research. 45: 454-62. PMID 21942864 DOI: 10.1021/ar200189b  1
2012 DeToma AS, Salamekh S, Ramamoorthy A, Lim MH. Misfolded proteins in Alzheimer's disease and type II diabetes. Chemical Society Reviews. 41: 608-21. PMID 21818468 DOI: 10.1039/c1cs15112f  1
2011 Tomonaga Y, Hidaka T, Kawamura I, Nishio T, Ohsawa K, Okitsu T, Wada A, Sudo Y, Kamo N, Ramamoorthy A, Naito A. An active photoreceptor intermediate revealed by in situ photoirradiated solid-state NMR spectroscopy. Biophysical Journal. 101: L50-2. PMID 22098758 DOI: 10.1016/j.bpj.2011.10.022  1
2011 Somashekar BS, Kamarajan P, Danciu T, Kapila YL, Chinnaiyan AM, Rajendiran TM, Ramamoorthy A. Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues. Journal of Proteome Research. 10: 5232-41. PMID 21961579 DOI: 10.1021/pr200800w  1
2011 Braymer JJ, Choi JS, DeToma AS, Wang C, Nam K, Kampf JW, Ramamoorthy A, Lim MH. Development of bifunctional stilbene derivatives for targeting and modulating metal-amyloid-β species. Inorganic Chemistry. 50: 10724-34. PMID 21954910 DOI: 10.1021/ic2012205  1
2011 Yamamoto K, Vivekanandan S, Ramamoorthy A. Fast NMR data acquisition from bicelles containing a membrane-associated peptide at natural-abundance. The Journal of Physical Chemistry. B. 115: 12448-55. PMID 21939237 DOI: 10.1021/jp2076098  1
2011 Khitrin AK, Xu J, Ramamoorthy A. Cross-correlations between low-γ nuclei in solids via a common dipolar bath. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 212: 95-101. PMID 21820340 DOI: 10.1016/j.jmr.2011.06.015  1
2011 Xu J, Zhu P, Morris MD, Ramamoorthy A. Solid-state NMR spectroscopy provides atomic-level insights into the dehydration of cartilage. The Journal of Physical Chemistry. B. 115: 9948-54. PMID 21786810 DOI: 10.1021/jp205663z  1
2011 Vivekanandan S, Brender JR, Lee SY, Ramamoorthy A. A partially folded structure of amyloid-beta(1-40) in an aqueous environment. Biochemical and Biophysical Research Communications. 411: 312-6. PMID 21726530 DOI: 10.1016/j.bbrc.2011.06.133  1
2011 Nanga RP, Brender JR, Vivekanandan S, Ramamoorthy A. Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment. Biochimica Et Biophysica Acta. 1808: 2337-42. PMID 21723249 DOI: 10.1016/j.bbamem.2011.06.012  1
2011 Salamekh S, Brender JR, Hyung SJ, Nanga RP, Vivekanandan S, Ruotolo BT, Ramamoorthy A. A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc. Journal of Molecular Biology. 410: 294-306. PMID 21616080 DOI: 10.1016/j.jmb.2011.05.015  1
2011 Yang P, Ramamoorthy A, Chen Z. Membrane orientation of MSI-78 measured by sum frequency generation vibrational spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 7760-7. PMID 21595453 DOI: 10.1021/la201048t  1
2011 Yoo SI, Yang M, Brender JR, Subramanian V, Sun K, Joo NE, Jeong SH, Ramamoorthy A, Kotov NA. Inhibition of amyloid peptide fibrillation by inorganic nanoparticles: functional similarities with proteins. Angewandte Chemie (International Ed. in English). 50: 5110-5. PMID 21495130 DOI: 10.1002/anie.201007824  1
2011 Xu J, Smith PE, Soong R, Ramamoorthy A. A proton spin diffusion based solid-state NMR approach for structural studies on aligned samples. The Journal of Physical Chemistry. B. 115: 4863-71. PMID 21466219 DOI: 10.1021/jp201501q  1
2011 Ramamoorthy A, Skaar TC. In Silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes Drug Metabolism Letters. 5: 126-131. PMID 21457141 DOI: 10.2174/187231211795305258  0.44
2011 Ramamoorthy A, Skaar TC. Gene copy number variations: It is important to determine which allele is affected Pharmacogenomics. 12: 299-301. PMID 21449666 DOI: 10.2217/pgs.11.5  0.44
2011 Brender JR, Lee EL, Hartman K, Wong PT, Ramamoorthy A, Steel DG, Gafni A. Biphasic effects of insulin on islet amyloid polypeptide membrane disruption. Biophysical Journal. 100: 685-92. PMID 21281583 DOI: 10.1016/j.bpj.2010.09.070  1
2011 Lutker KM, Quiñones R, Xu J, Ramamoorthy A, Matzger AJ. Polymorphs and hydrates of acyclovir. Journal of Pharmaceutical Sciences. 100: 949-63. PMID 21280051 DOI: 10.1002/jps.22336  1
2011 Brender JR, Nanga RP, Popovych N, Soong R, Macdonald PM, Ramamoorthy A. The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency. Biochimica Et Biophysica Acta. 1808: 1161-9. PMID 21262195 DOI: 10.1016/j.bbamem.2011.01.010  1
2011 Zimmerman LB, Worley BV, Palermo EF, Brender JR, Lee KD, Kuroda K, Ramamoorthy A, Meyerhoff ME. Absorbance-based assay for membrane disruption by antimicrobial peptides and synthetic copolymers using pyrroloquinoline quinone-loaded liposomes. Analytical Biochemistry. 411: 194-9. PMID 21237129 DOI: 10.1016/j.ab.2011.01.009  1
2011 Palermo EF, Lee DK, Ramamoorthy A, Kuroda K. Role of cationic group structure in membrane binding and disruption by amphiphilic copolymers. The Journal of Physical Chemistry. B. 115: 366-75. PMID 21171655 DOI: 10.1021/jp1083357  1
2010 Choi JS, Braymer JJ, Nanga RP, Ramamoorthy A, Lim MH. Design of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 107: 21990-5. PMID 21131570 DOI: 10.1073/pnas.1006091107  1
2010 Domadia PN, Bhunia A, Ramamoorthy A, Bhattacharjya S. Structure, interactions, and antibacterial activities of MSI-594 derived mutant peptide MSI-594F5A in lipopolysaccharide micelles: role of the helical hairpin conformation in outer-membrane permeabilization. Journal of the American Chemical Society. 132: 18417-28. PMID 21128620 DOI: 10.1021/ja1083255  1
2010 Thennarasu S, Huang R, Lee DK, Yang P, Maloy L, Chen Z, Ramamoorthy A. Limiting an antimicrobial peptide to the lipid-water interface enhances its bacterial membrane selectivity: a case study of MSI-367. Biochemistry. 49: 10595-605. PMID 21062093 DOI: 10.1021/bi101394r  1
2010 Nguyen KT, Soong R, Lm SC, Waskell L, Ramamoorthy A, Chen Z. Probing the spontaneous membrane insertion of a tail-anchored membrane protein by sum frequency generation spectroscopy. Journal of the American Chemical Society. 132: 15112-5. PMID 20932011 DOI: 10.1021/ja106508f  1
2010 Xu J, Zhu P, Gan Z, Sahar N, Tecklenburg M, Morris MD, Kohn DH, Ramamoorthy A. Natural-abundance 43Ca solid-state NMR spectroscopy of bone. Journal of the American Chemical Society. 132: 11504-9. PMID 20681578 DOI: 10.1021/ja101961x  1
2010 Xu J, Soong R, Im SC, Waskell L, Ramamoorthy A. INEPT-based separated-local-field NMR spectroscopy: a unique approach to elucidate side-chain dynamics of membrane-associated proteins. Journal of the American Chemical Society. 132: 9944-7. PMID 20593897 DOI: 10.1021/ja103983f  1
2010 Brender JR, Hartman K, Nanga RP, Popovych N, de la Salud Bea R, Vivekanandan S, Marsh EN, Ramamoorthy A. Role of zinc in human islet amyloid polypeptide aggregation. Journal of the American Chemical Society. 132: 8973-83. PMID 20536124 DOI: 10.1021/ja1007867  1
2010 Epand RF, Maloy L, Ramamoorthy A, Epand RM. Amphipathic helical cationic antimicrobial peptides promote rapid formation of crystalline states in the presence of phosphatidylglycerol: lipid clustering in anionic membranes. Biophysical Journal. 98: 2564-73. PMID 20513400 DOI: 10.1016/j.bpj.2010.03.002  0.92
2010 Smith PE, Brender JR, Dürr UH, Xu J, Mullen DG, Banaszak Holl MM, Ramamoorthy A. Solid-state NMR reveals the hydrophobic-core location of poly(amidoamine) dendrimers in biomembranes. Journal of the American Chemical Society. 132: 8087-97. PMID 20481633 DOI: 10.1021/ja101524z  1
2010 Yamamoto K, Xu J, Kawulka KE, Vederas JC, Ramamoorthy A. Use of a copper-chelated lipid speeds up NMR measurements from membrane proteins. Journal of the American Chemical Society. 132: 6929-31. PMID 20433169 DOI: 10.1021/ja102103n  1
2010 Epand RF, Maloy WL, Ramamoorthy A, Epand RM. Probing the "charge cluster mechanism" in amphipathic helical cationic antimicrobial peptides. Biochemistry. 49: 4076-84. PMID 20387900 DOI: 10.1021/bi100378m  1
2010 Thennarasu S, Tan A, Penumatchu R, Shelburne CE, Heyl DL, Ramamoorthy A. Antimicrobial and membrane disrupting activities of a peptide derived from the human cathelicidin antimicrobial peptide LL37. Biophysical Journal. 98: 248-57. PMID 20338846 DOI: 10.1016/j.bpj.2009.09.060  1
2010 Soong R, Smith PE, Xu J, Yamamoto K, Im SC, Waskell L, Ramamoorthy A. Proton-evolved local-field solid-state NMR studies of cytochrome b5 embedded in bicelles, revealing both structural and dynamical information. Journal of the American Chemical Society. 132: 5779-88. PMID 20334357 DOI: 10.1021/ja910807e  1
2010 Veglia G, Ramamoorthy A. Special issue on "membrane protein dynamics: correlating structure to function". Biochimica Et Biophysica Acta. 1798: 65-7. PMID 20103412 DOI: 10.1016/j.bbamem.2009.12.026  1
2010 Bhunia A, Domadia PN, Torres J, Hallock KJ, Ramamoorthy A, Bhattacharjya S. NMR structure of pardaxin, a pore-forming antimicrobial peptide, in lipopolysaccharide micelles: mechanism of outer membrane permeabilization. The Journal of Biological Chemistry. 285: 3883-95. PMID 19959835 DOI: 10.1074/jbc.M109.065672  1
2010 Io T, Fukami T, Yamamoto K, Suzuki T, Xu J, Tomono K, Ramamoorthy A. Homogeneous nanoparticles to enhance the efficiency of a hydrophobic drug, antihyperlipidemic probucol, characterized by solid-state NMR. Molecular Pharmaceutics. 7: 299-305. PMID 19938876 DOI: 10.1021/mp900254y  1
2010 Ramamoorthy A, Lee DK, Narasimhaswamy T, Nanga RP. Cholesterol reduces pardaxin's dynamics-a barrel-stave mechanism of membrane disruption investigated by solid-state NMR. Biochimica Et Biophysica Acta. 1798: 223-7. PMID 19716800 DOI: 10.1016/j.bbamem.2009.08.012  1
2009 Nanga RP, Brender JR, Vivekanandan S, Popovych N, Ramamoorthy A. NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286). Journal of the American Chemical Society. 131: 17972-9. PMID 19995078 DOI: 10.1021/ja908170s  1
2009 Zhu P, Xu J, Sahar N, Morris MD, Kohn DH, Ramamoorthy A. Time-resolved dehydration-induced structural changes in an intact bovine cortical bone revealed by solid-state NMR spectroscopy. Journal of the American Chemical Society. 131: 17064-5. PMID 19894735 DOI: 10.1021/ja9081028  1
2009 Brender JR, Hartman K, Gottler LM, Cavitt ME, Youngstrom DW, Ramamoorthy A. Helical conformation of the SEVI precursor peptide PAP248-286, a dramatic enhancer of HIV infectivity, promotes lipid aggregation and fusion. Biophysical Journal. 97: 2474-83. PMID 19883590 DOI: 10.1016/j.bpj.2009.08.034  1
2009 Hindo SS, Mancino AM, Braymer JJ, Liu Y, Vivekanandan S, Ramamoorthy A, Lim MH. Small molecule modulators of copper-induced Abeta aggregation. Journal of the American Chemical Society. 131: 16663-5. PMID 19877631 DOI: 10.1021/ja907045h  1
2009 Bhattacharjya S, Ramamoorthy A. Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides. The Febs Journal. 276: 6465-73. PMID 19817858 DOI: 10.1111/j.1742-4658.2009.07357.x  1
2009 Marsh EN, Buer BC, Ramamoorthy A. Fluorine--a new element in the design of membrane-active peptides. Molecular Biosystems. 5: 1143-7. PMID 19756303 DOI: 10.1039/b909864j  1
2009 Nanga RP, Brender JR, Xu J, Hartman K, Subramanian V, Ramamoorthy A. Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy. Journal of the American Chemical Society. 131: 8252-61. PMID 19456151 DOI: 10.1021/ja9010095  1
2009 Soong R, Brender JR, Macdonald PM, Ramamoorthy A. Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy. Journal of the American Chemical Society. 131: 7079-85. PMID 19405534 DOI: 10.1021/ja900285z  1
2009 Yamamoto K, Soong R, Ramamoorthy A. Comprehensive analysis of lipid dynamics variation with lipid composition and hydration of bicelles using nuclear magnetic resonance (NMR) spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 7010-8. PMID 19397253 DOI: 10.1021/la900200s  1
2009 Ramamoorthy A. Beyond NMR spectra of antimicrobial peptides: dynamical images at atomic resolution and functional insights. Solid State Nuclear Magnetic Resonance. 35: 201-7. PMID 19386477 DOI: 10.1016/j.ssnmr.2009.03.003  1
2009 Fukami T, Ishii T, Io T, Suzuki N, Suzuki T, Yamamoto K, Xu J, Ramamoorthy A, Tomono K. Nanoparticle processing in the solid state dramatically increases the cell membrane permeation of a cholesterol-lowering drug, probucol. Molecular Pharmaceutics. 6: 1029-35. PMID 19281185 DOI: 10.1021/mp9000487  1
2009 Smith PE, Brender JR, Ramamoorthy A. Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide. Journal of the American Chemical Society. 131: 4470-8. PMID 19278224 DOI: 10.1021/ja809002a  1
2009 Barry J, Fritz M, Brender JR, Smith PE, Lee DK, Ramamoorthy A. Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin. Journal of the American Chemical Society. 131: 4490-8. PMID 19256547 DOI: 10.1021/ja809217u  1
2009 Bhunia A, Ramamoorthy A, Bhattacharjya S. Helical hairpin structure of a potent antimicrobial peptide MSI-594 in lipopolysaccharide micelles by NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 2036-40. PMID 19180607 DOI: 10.1002/chem.200802635  1
2009 Kandasamy SK, Lee DK, Nanga RP, Xu J, Santos JS, Larson RG, Ramamoorthy A. Solid-state NMR and molecular dynamics simulations reveal the oligomeric ion-channels of TM2-GABA(A) stabilized by intermolecular hydrogen bonding. Biochimica Et Biophysica Acta. 1788: 686-95. PMID 19071084 DOI: 10.1016/j.bbamem.2008.11.009  1
2009 Fukuchi M, Ramamoorthy A, Takegoshi K. Efficient cross-polarization using a composite 0 degrees pulse for NMR studies on static solids. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 196: 105-9. PMID 19022690 DOI: 10.1016/j.jmr.2008.10.013  1
2009 Gottler LM, Ramamoorthy A. Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. Biochimica Et Biophysica Acta. 1788: 1680-6. PMID 19010301 DOI: 10.1016/j.bbamem.2008.10.009  0.92
2008 Lee DK, Kwon BS, Ramamoorthy A. Freezing point depression of water in phospholipid membranes: a solid-state NMR study. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 13598-604. PMID 18991419 DOI: 10.1021/la8023698  1
2008 Brender JR, Hartman K, Reid KR, Kennedy RT, Ramamoorthy A. A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry. 47: 12680-8. PMID 18989933 DOI: 10.1021/bi801427c  1
2008 Nanga RP, Brender JR, Xu J, Veglia G, Ramamoorthy A. Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy. Biochemistry. 47: 12689-97. PMID 18989932 DOI: 10.1021/bi8014357  1
2008 Xu J, Dürr UH, Im SC, Gan Z, Waskell L, Ramamoorthy A. Bicelle-enabled structural studies on a membrane-associated cytochrome B5 by solid-state MAS NMR spectroscopy. Angewandte Chemie (International Ed. in English). 47: 7864-7. PMID 18792050 DOI: 10.1002/anie.200801338  1
2008 Dvinskikh SV, Yamamoto K, Scanu D, Deschenaux R, Ramamoorthy A. High-resolution characterization of liquid-crystalline [60]fullerenes using solid-state nuclear magnetic resonance spectroscopy. The Journal of Physical Chemistry. B. 112: 12347-53. PMID 18781716 DOI: 10.1021/jp803265z  1
2008 Gottler LM, de la Salud Bea R, Shelburne CE, Ramamoorthy A, Marsh EN. Using fluorous amino acids to probe the effects of changing hydrophobicity on the physical and biological properties of the beta-hairpin antimicrobial peptide protegrin-1. Biochemistry. 47: 9243-50. PMID 18693751 DOI: 10.1021/bi801045n  1
2008 Ramamoorthy A, Lee DK, Santos JS, Henzler-Wildman KA. Nitrogen-14 solid-state NMR spectroscopy of aligned phospholipid bilayers to probe peptide-lipid interaction and oligomerization of membrane associated peptides. Journal of the American Chemical Society. 130: 11023-9. PMID 18646853 DOI: 10.1021/ja802210u  1
2008 Brender JR, Lee EL, Cavitt MA, Gafni A, Steel DG, Ramamoorthy A. Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide. Journal of the American Chemical Society. 130: 6424-9. PMID 18444645 DOI: 10.1021/ja710484d  1
2008 Porcelli F, Verardi R, Shi L, Henzler-Wildman KA, Ramamoorthy A, Veglia G. NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles. Biochemistry. 47: 5565-72. PMID 18439024 DOI: 10.1021/bi702036s  1
2008 Xu J, Struppe J, Ramamoorthy A. Two-dimensional homonuclear chemical shift correlation established by the cross-relaxation driven spin diffusion in solids. The Journal of Chemical Physics. 128: 052308. PMID 18266425 DOI: 10.1063/1.2826323  1
2008 Gottler LM, Lee HY, Shelburne CE, Ramamoorthy A, Marsh EN. Using fluorous amino acids to modulate the biological activity of an antimicrobial peptide. Chembiochem : a European Journal of Chemical Biology. 9: 370-3. PMID 18224631 DOI: 10.1002/cbic.200700643  1
2008 Hoskin DW, Ramamoorthy A. Studies on anticancer activities of antimicrobial peptides. Biochimica Et Biophysica Acta. 1778: 357-75. PMID 18078805 DOI: 10.1016/j.bbamem.2007.11.008  1
2007 Ramamoorthy A. NMR structural studies on membrane proteins. Biochimica Et Biophysica Acta. 1768: 2947-8. PMID 18083365 DOI: 10.1016/j.bbamem.2007.12.001  1
2007 Dürr UHN, Waskell L, Ramamoorthy A. The cytochromes P450 and b5 and their reductases-Promising targets for structural studies by advanced solid-state NMR spectroscopy Biochimica Et Biophysica Acta - Biomembranes. 1768: 3235-3259. PMID 17945183 DOI: 10.1016/j.bbamem.2007.08.007  1
2007 Podsiadlo P, Kaushik AK, Arruda EM, Waas AM, Shim BS, Xu J, Nandivada H, Pumplin BG, Lahann J, Ramamoorthy A, Kotov NA. Ultrastrong and stiff layered polymer nanocomposites. Science (New York, N.Y.). 318: 80-3. PMID 17916728 DOI: 10.1126/science.1143176  1
2007 Brender JR, Dürr UH, Heyl D, Budarapu MB, Ramamoorthy A. Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes. Biochimica Et Biophysica Acta. 1768: 2026-9. PMID 17662957 DOI: 10.1016/j.bbamem.2007.07.001  1
2007 Dürr UH, Yamamoto K, Im SC, Waskell L, Ramamoorthy A. Solid-state NMR reveals structural and dynamical properties of a membrane-anchored electron-carrier protein, cytochrome b5. Journal of the American Chemical Society. 129: 6670-1. PMID 17488074 DOI: 10.1021/ja069028m  1
2007 Dvinskikh SV, Dürr UH, Yamamoto K, Ramamoorthy A. High-resolution 2D NMR spectroscopy of bicelles to measure the membrane interaction of ligands. Journal of the American Chemical Society. 129: 794-802. PMID 17243815 DOI: 10.1021/ja065536k  1
2007 Ramamoorthy A, Kandasamy SK, Lee DK, Kidambi S, Larson RG. Structure, topology, and tilt of cell-signaling peptides containing nuclear localization sequences in membrane bilayers determined by solid-state NMR and molecular dynamics simulation studies. Biochemistry. 46: 965-75. PMID 17240980 DOI: 10.1021/bi061895g  1
2007 Shelburne CE, An FY, Dholpe V, Ramamoorthy A, Lopatin DE, Lantz MS. The spectrum of antimicrobial activity of the bacteriocin subtilosin A. The Journal of Antimicrobial Chemotherapy. 59: 297-300. PMID 17213266 DOI: 10.1093/jac/dkl495  1
2007 Dvinskikh SV, Yamamoto K, Dürr UH, Ramamoorthy A. Sensitivity and resolution enhancement in solid-state NMR spectroscopy of bicelles. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 184: 228-35. PMID 17084096 DOI: 10.1016/j.jmr.2006.10.004  1
2006 Dhople V, Krukemeyer A, Ramamoorthy A. The human beta-defensin-3, an antibacterial peptide with multiple biological functions Biochimica Et Biophysica Acta - Biomembranes. 1758: 1499-1512. PMID 16978580 DOI: 10.1016/j.bbamem.2006.07.007  1
2006 Dvinskikh SV, Yamamoto K, Ramamoorthy A. Heteronuclear isotropic mixing separated local field NMR spectroscopy. The Journal of Chemical Physics. 125: 34507. PMID 16863362 DOI: 10.1063/1.2212939  1
2006 Dürr UH, Sudheendra US, Ramamoorthy A. LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochimica Et Biophysica Acta. 1758: 1408-25. PMID 16716248 DOI: 10.1016/j.bbamem.2006.03.030  1
2006 Ramamoorthy A, Thennarasu S, Tan A, Gottipati K, Sreekumar S, Heyl DL, An FY, Shelburne CE. Deletion of all cysteines in tachyplesin I abolishes hemolytic activity and retains antimicrobial activity and lipopolysaccharide selective binding. Biochemistry. 45: 6529-40. PMID 16700563 DOI: 10.1021/bi052629q  1
2006 Dvinskikh S, Dürr U, Yamamoto K, Ramamoorthy A. A high-resolution solid-state NMR approach for the structural studies of bicelles. Journal of the American Chemical Society. 128: 6326-7. PMID 16683791 DOI: 10.1021/ja061153a  1
2006 Porcelli F, Buck-Koehntop BA, Thennarasu S, Ramamoorthy A, Veglia G. Structures of the dimeric and monomeric variants of magainin antimicrobial peptides (MSI-78 and MSI-594) in micelles and bilayers, determined by NMR spectroscopy. Biochemistry. 45: 5793-9. PMID 16669623 DOI: 10.1021/bi0601813  1
2006 Ramamoorthy A, Thennarasu S, Lee DK, Tan A, Maloy L. Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin. Biophysical Journal. 91: 206-16. PMID 16603496 DOI: 10.1529/biophysj.105.073890  1
2006 Ramamoorthy A, Thennarasu S, Tan A, Lee DK, Clayberger C, Krensky AM. Cell selectivity correlates with membrane-specific interactions: a case study on the antimicrobial peptide G15 derived from granulysin. Biochimica Et Biophysica Acta. 1758: 154-63. PMID 16579960 DOI: 10.1016/j.bbamem.2006.02.014  1
2006 Moon JY, Henzler-Wildman KA, Ramamoorthy A. Expression and purification of a recombinant LL-37 from Escherichia coli. Biochimica Et Biophysica Acta. 1758: 1351-8. PMID 16542635 DOI: 10.1016/j.bbamem.2006.02.003  0.92
2006 Epand RF, Ramamoorthy A, Epand RM. Membrane lipid composition and the interaction of pardaxin: the role of cholesterol. Protein and Peptide Letters. 13: 1-5. PMID 16454662  1
2005 Narasimhaswamy T, Monette M, Lee DK, Ramamoorthy A. Solid-state NMR characterization and determination of the orientational order of a nematogen Journal of Physical Chemistry B. 109: 19696-19703. PMID 16853547 DOI: 10.1021/jp052343v  1
2005 Yamamoto K, Ermakov VL, Lee DK, Ramamoorthy A. PITANSEMA-MAS, a solid-state NMR method to measure heteronuclear dipolar couplings under MAS. Chemical Physics Letters. 408: 118-122. PMID 16652173 DOI: 10.1016/j.cplett.2005.04.017  1
2005 Powers JP, Tan A, Ramamoorthy A, Hancock RE. Solution structure and interaction of the antimicrobial polyphemusins with lipid membranes. Biochemistry. 44: 15504-13. PMID 16300399 DOI: 10.1021/bi051302m  0.72
2005 Mecke A, Lee DK, Ramamoorthy A, Orr BG, Banaszak Holl MM. Membrane thinning due to antimicrobial peptide binding: an atomic force microscopy study of MSI-78 in lipid bilayers. Biophysical Journal. 89: 4043-50. PMID 16183881 DOI: 10.1529/biophysj.105.062596  1
2005 Mecke A, Lee DK, Ramamoorthy A, Orr BG, Holl MM. Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 8588-90. PMID 16142931 DOI: 10.1021/la051800w  1
2005 Thennarasu S, Lee DK, Poon A, Kawulka KE, Vederas JC, Ramamoorthy A. Membrane permeabilization, orientation, and antimicrobial mechanism of subtilosin A. Chemistry and Physics of Lipids. 137: 38-51. PMID 16095584 DOI: 10.1016/j.chemphyslip.2005.06.003  1
2005 Thennarasu S, Lee DK, Tan A, Prasad Kari U, Ramamoorthy A. Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843. Biochimica Et Biophysica Acta. 1711: 49-58. PMID 15904663 DOI: 10.1016/j.bbamem.2005.02.010  1
2005 Narasimhaswamy T, Lee DK, Yamamoto K, Somanathan N, Ramamoorthy A. A 2D solid-state NMR experiment to resolve overlapping aromatic resonances of thiophene-based nematogens. Journal of the American Chemical Society. 127: 6958-9. PMID 15884932 DOI: 10.1021/ja051160j  1
2004 Poon A, Birn J, Ramamoorthy A. How Does an Amide-N Chemical Shift Tensor Vary in Peptides? The Journal of Physical Chemistry. B. 108: 16577-16585. PMID 18449362 DOI: 10.1021/jp0471913  1
2004 Pointer-Keenan CD, Lee DK, Hallok K, Tan A, Zand R, Ramamoorthy A. Investigation of the interaction of myelin basic protein with phospholipid bilayers using solid-state NMR spectroscopy. Chemistry and Physics of Lipids. 132: 47-54. PMID 15530447 DOI: 10.1016/j.chemphyslip.2004.09.004  1
2004 Mecke A, Uppuluri S, Sassanella TM, Lee DK, Ramamoorthy A, Baker JR, Orr BG, Banaszak Holl MM. Direct observation of lipid bilayer disruption by poly(amidoamine) dendrimers. Chemistry and Physics of Lipids. 132: 3-14. PMID 15530443 DOI: 10.1016/j.chemphyslip.2004.09.001  1
2004 Porcelli F, Buck B, Lee DK, Hallock KJ, Ramamoorthy A, Veglia G. Structure and orientation of pardaxin determined by NMR experiments in model membranes. The Journal of Biological Chemistry. 279: 45815-23. PMID 15292173 DOI: 10.1074/jbc.M405454200  1
2004 Birn J, Poon A, Mao Y, Ramamoorthy A. Ab initio study of (13)C(alpha) chemical shift anisotropy tensors in peptides. Journal of the American Chemical Society. 126: 8529-34. PMID 15238010 DOI: 10.1021/ja049879z  0.36
2004 Henzler-Wildman KA, Martinez GV, Brown MF, Ramamoorthy A. Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37. Biochemistry. 43: 8459-69. PMID 15222757 DOI: 10.1021/bi036284s  0.92
2004 Henzler Wildman KA, Ramamoorthy A, Wakamiya T, Yoshikawa T, Crisma M, Toniolo C, Formaggio F. A study of a Calpha,beta-didehydroalanine homo-oligopeptide series in the solid-state by 13C cross-polarization magic angle spinning NMR. Journal of Peptide Science : An Official Publication of the European Peptide Society. 10: 336-41. PMID 15214438 DOI: 10.1002/psc.551  0.84
2004 Lee DK, Wildman KH, Ramamoorthy A. Solid-state NMR spectroscopy of aligned lipid bilayers at low temperatures. Journal of the American Chemical Society. 126: 2318-9. PMID 14982431 DOI: 10.1021/ja039077o  1
2004 Santos JS, Lee DK, Ramamoorthy A. Effects of antidepressants on the conformation of phospholipid headgroups studied by solid-state NMR. Magnetic Resonance in Chemistry : Mrc. 42: 105-14. PMID 14745789 DOI: 10.1002/mrc.1327  1
2003 Henzler Wildman KA, Wilson EE, Lee DK, Ramamoorthy A. Determination of the conformation and stability of simple homopolypeptides using solid-state NMR. Solid State Nuclear Magnetic Resonance. 24: 94-109. PMID 12943907  1
2003 Henzler Wildman KA, Lee DK, Ramamoorthy A. Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37. Biochemistry. 42: 6545-58. PMID 12767238 DOI: 10.1021/bi0273563  1
2003 Hallock KJ, Lee DK, Ramamoorthy A. MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain. Biophysical Journal. 84: 3052-60. PMID 12719236 DOI: 10.1016/S0006-3495(03)70031-9  1
2003 Mascioni A, Porcelli F, Ilangovan U, Ramamoorthy A, Veglia G. Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study. Biopolymers. 69: 29-41. PMID 12717720 DOI: 10.1002/bip.10305  1
2003 Kidambi SS, Lee DK, Ramamoorthy A. Interaction of Cd and Zn with biologically important ligands characterized using solid-state NMR and ab initio calculations. Inorganic Chemistry. 42: 3142-51. PMID 12716214 DOI: 10.1021/ic026287d  1
2003 Kidambi SS, Ramamoorthy A. Characterization of metal centers in bioinorganic complexes using ab initio calculations of 113Cd chemical shifts. Inorganic Chemistry. 42: 2200-2. PMID 12665351 DOI: 10.1021/ic026165l  1
2002 Wei Y, Lee DK, McDermott AE, Ramamoorthy A. A 2D MAS solid-state NMR method to recover the amplified heteronuclear dipolar and chemical shift anisotropic interactions. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 158: 23-35. PMID 12419668  1
2002 Shekar SC, Lee DK, Ramamoorthy A. Chemical shift anisotropy and offset effects in cross polarization solid-state NMR spectroscopy Journal of Magnetic Resonance. 157: 223-234. PMID 12323141 DOI: 10.1006/jmre.2002.2587  1
2002 Hallock KJ, Lee DK, Omnaas J, Mosberg HI, Ramamoorthy A. Membrane composition determines pardaxin's mechanism of lipid bilayer disruption. Biophysical Journal. 83: 1004-13. PMID 12124282 DOI: 10.1016/S0006-3495(02)75226-0  1
2002 Henzler Wildman KA, Lee DK, Ramamoorthy A. Determination of alpha-helix and beta-sheet stability in the solid state: a solid-state NMR investigation of poly(L-alanine). Biopolymers. 64: 246-54. PMID 12115132 DOI: 10.1002/bip.10180  1
2002 Shekar SC, Ramamoorthy A, Wittebort RJ. Determination of the chemical shielding tensor orientation from two or one of the three conventional rotations of a single crystal. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 155: 257-62. PMID 12036337 DOI: 10.1006/jmre.2002.2518  1
2002 Hallock KJ, Henzler Wildman K, Lee DK, Ramamoorthy A. An innovative procedure using a sublimable solid to align lipid bilayers for solid-state NMR studies. Biophysical Journal. 82: 2499-503. PMID 11964237 DOI: 10.1016/S0006-3495(02)75592-6  1
2001 Shekar SC, Lee DK, Ramamoorthy A. An experimental strategy to dramatically reduce the RF power used in cross polarization solid-state NMR spectroscopy [23] Journal of the American Chemical Society. 123: 7467-7468. PMID 11472196 DOI: 10.1021/ja016212t  1
2001 Brender JR, Taylor DM, Ramamoorthy A. Orientation of amide-nitrogen-15 chemical shift tensors in peptides: a quantum chemical study. Journal of the American Chemical Society. 123: 914-22. PMID 11456625  1
2001 Wei Y, Lee DK, Ramamoorthy A. Solid-state (13)C NMR chemical shift anisotropy tensors of polypeptides. Journal of the American Chemical Society. 123: 6118-26. PMID 11414846  1
2000 Stout KL, Hallock KJ, Kampf JW, Ramamoorthy A. N-Acetyl-L-phenylalanine. Acta Crystallographica. Section C, Crystal Structure Communications. 56: E100. PMID 15263215 DOI: 10.1107/S0108270100001712  1
1999 Taylor DM, Ramamoorthy A. Analysis of dipolar-coupling-mediated coherence transfer in a homonuclear two spin-12 solid-state system Journal of Magnetic Resonance (San Diego, Calif. : 1997). 141: 18-28. PMID 10527739 DOI: 10.1006/jmre.1999.1893  1
1999 Ramamoorthy A, Wu CH, Opella SJ. Experimental aspects of multidimensional solid-state NMR correlation spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 140: 131-40. PMID 10479555 DOI: 10.1006/jmre.1999.1827  1
1998 Lee DK, Ramamoorthy A. A Simple One-Dimensional Solid-State NMR Method to Characterize the Nuclear Spin Interaction Tensors Associated with the Peptide Bond Journal of Magnetic Resonance. 133: 204-206. PMID 9654488  1
1998 Ilangovan U, Ramamoorthy A. Conformational studies of human islet amyloid peptide using molecular dynamics and simulated annealing methods Biopolymers. 45: 9-20. PMID 9433183 DOI: 10.1002/(SICI)1097-0282(199801)45:1<9::AID-BIP2>3.0.CO;2-X  1
1997 Marassi FM, Ramamoorthy A, Opella SJ. Complete resolution of the solid-state NMR spectrum of a uniformly 15N-labeled membrane protein in phospholipid bilayers. Proceedings of the National Academy of Sciences of the United States of America. 94: 8551-6. PMID 9238014  1
1996 Ramamoorthy A, Gierasch LM, Opella SJ. Three-dimensional solid-state NMR correlation experiment with 1H homonuclear spin exchange. Journal of Magnetic Resonance. Series B. 111: 81-4. PMID 8620287  1
1996 Ramamoorthy A, Gierasch LM, Opella SJ. Resolved two-dimensional anisotropic-chemical-shift/heteronuclear dipolar coupling powder-pattern spectra by three-dimensional solid-state NMR spectroscopy. Journal of Magnetic Resonance. Series B. 110: 102-6. PMID 8556232  1
1995 Ramamoorthy A, Opella SJ. Two-dimensional chemical shift/heteronuclear dipolar coupling spectra obtained with polarization inversion spin exchange at the magic angle and magic-angle sample spinning (PISEMAMAS). Solid State Nuclear Magnetic Resonance. 4: 387-92. PMID 8581437  1
1995 Ramamoorthy A, Gierasch LM, Opella SJ. Four-dimensional solid-state NMR experiment that correlates the chemical-shift and dipolar-coupling frequencies of two heteronuclei with the exchange of dilute-spin magnetization. Journal of Magnetic Resonance. Series B. 109: 112-6. PMID 8581306  1
1995 Ramamoorthy A, Marassi FM, Zasloff M, Opella SJ. Three-dimensional solid-state NMR spectroscopy of a peptide oriented in membrane bilayers. Journal of Biomolecular Nmr. 6: 329-34. PMID 8520224  1
1995 Ramamoorthy A, Wu CH, Opella SJ. Three-dimensional solid-state NMR experiment that correlates the chemical shift and dipolar coupling frequencies of two heteronuclei. Journal of Magnetic Resonance. Series B. 107: 88-90. PMID 7743077  1
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