Steven Owen Smith - Publications

Affiliations: 
Biochemistry Stony Brook University, Stony Brook, NY, United States 
Area:
membrane and amyloid proteins
Website:
https://www.stonybrook.edu/commcms/biochem/research/faculty/smith/

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tang TC, Kienlen-Campard P, Hu Y, Perrin F, Opsomer R, Octave JN, Constantinescu SN, Smith SO. Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and γ-secretase processing of the C99 peptide. The Journal of Biological Chemistry. PMID 30755484 DOI: 10.1074/jbc.RA118.006061  0.32
2019 Defour JP, Levy G, Leroy E, Smith SO, Constantinescu SN. The S505A thrombopoietin receptor mutation in childhood hereditary thrombocytosis and essential thrombocythemia is S505N: single letter amino acid code matters. Leukemia. PMID 30635630 DOI: 10.1038/s41375-018-0356-x  0.32
2018 Chung H, Crooks EJ, Ziliox M, Smith SO. Disaggregation of Aβ42 for Structural and Biochemical Studies. Methods in Molecular Biology (Clifton, N.J.). 1777: 321-330. PMID 29744845 DOI: 10.1007/978-1-4939-7811-3_20  0.44
2017 Hu Y, Kienlen-Campard P, Tang TC, Perrin F, Opsomer R, Decock M, Pan X, Octave JN, Constantinescu SN, Smith SO. β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic Processing. Scientific Reports. 7: 17159. PMID 29215043 DOI: 10.1038/s41598-017-17144-0  0.32
2017 Sanchez-Reyes OB, Cooke ALG, Tranter DB, Rashid D, Eilers M, Reeves PJ, Smith SO. G Protein-Coupled Receptors Contain Two Conserved Packing Clusters. Biophysical Journal. 112: 2315-2326. PMID 28591604 DOI: 10.1016/j.bpj.2017.04.051  0.44
2016 Xu F, Fu Z, Dass S, Kotarba AE, Davis J, Smith SO, Van Nostrand WE. Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure. Nature Communications. 7: 13527. PMID 27869115 DOI: 10.1038/ncomms13527  0.32
2016 Kimata N, Pope A, Eilers M, Opefi CA, Ziliox M, Hirshfeld A, Zaitseva E, Vogel R, Sheves M, Reeves PJ, Smith SO. Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation. Nature Communications. 7: 12683. PMID 27585742 DOI: 10.1038/ncomms12683  1
2016 Kimata N, Pope A, Sanchez-Reyes OB, Eilers M, Opefi CA, Ziliox M, Reeves PJ, Smith SO. Free backbone carbonyls mediate rhodopsin activation. Nature Structural & Molecular Biology. PMID 27376589 DOI: 10.1038/nsmb.3257  1
2016 Decock M, Stanga S, Octave JN, Dewachter I, Smith SO, Constantinescu SN, Kienlen-Campard P. Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells. Frontiers in Aging Neuroscience. 8: 107. PMID 27242518 DOI: 10.3389/fnagi.2016.00107  0.32
2015 Leroy E, Defour JP, Sato T, Dass S, Gryshkova V, Myat Marlar S, Staerk J, Constantinescu SN, Smith SO. His499 Regulates Dimerization and Prevents Oncogenic Activation by Asparagine Mutations of the Human Thrombopoietin Receptor. The Journal of Biological Chemistry. PMID 26627830 DOI: 10.1074/jbc.M115.696534  1
2015 Decock M, El Haylani L, Stanga S, Dewachter I, Octave JN, Smith SO, Constantinescu SN, Kienlen-Campard P. Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing. Febs Open Bio. 5: 763-73. PMID 26500837 DOI: 10.1016/j.fob.2015.09.002  0.32
2015 Fu Z, Aucoin D, Davis J, Van Nostrand WE, Smith SO. Mechanism of Nucleated Conformational Conversion of Aβ42. Biochemistry. 54: 4197-207. PMID 26069943 DOI: 10.1021/acs.biochem.5b00467  1
2015 Opefi CA, Tranter D, Smith SO, Reeves PJ. Construction of stable mammalian cell lines for inducible expression of G protein-coupled receptors. Methods in Enzymology. 556: 283-305. PMID 25857787 DOI: 10.1016/bs.mie.2014.12.020  0.44
2015 Kimata N, Reeves PJ, Smith SO. Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 253: 111-8. PMID 25797010 DOI: 10.1016/j.jmr.2014.12.014  0.44
2015 Kimata N, Pope A, Rashid D, Reeves PJ, Smith SO. Sequential structural changes in rhodopsin occurring upon photoactivation. Methods in Molecular Biology (Clifton, N.J.). 1271: 159-71. PMID 25697523 DOI: 10.1007/978-1-4939-2330-4_11  1
2015 Marinangeli C, Tasiaux B, Opsomer R, Hage S, Sodero AO, Dewachter I, Octave JN, Smith SO, Constantinescu SN, Kienlen-Campard P. Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex. The Journal of Biological Chemistry. 290: 7169-84. PMID 25614624 DOI: 10.1074/jbc.M114.601286  0.32
2014 Fu Z, Aucoin D, Ahmed M, Ziliox M, Van Nostrand WE, Smith SO. Capping of aβ42 oligomers by small molecule inhibitors. Biochemistry. 53: 7893-903. PMID 25422864 DOI: 10.1021/bi500910b  1
2014 Tamagaki H, Furukawa Y, Yamaguchi R, Hojo H, Aimoto S, Smith SO, Sato T. Coupling of transmembrane helix orientation to membrane release of the juxtamembrane region in FGFR3. Biochemistry. 53: 5000-7. PMID 25010350 DOI: 10.1021/bi500327q  1
2014 Xu F, Kotarba AE, Ou-Yang MH, Fu Z, Davis J, Smith SO, Van Nostrand WE. Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice. The Journal of Biological Chemistry. 289: 17895-908. PMID 24828504 DOI: 10.1074/jbc.M113.536565  1
2014 Tang TC, Hu Y, Kienlen-Campard P, El Haylani L, Decock M, Van Hees J, Fu Z, Octave JN, Constantinescu SN, Smith SO. Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased Aβ production. Structure (London, England : 1993). 22: 387-96. PMID 24462250 DOI: 10.1016/j.str.2013.12.012  0.32
2014 Pope A, Eilers M, Reeves PJ, Smith SO. Amino acid conservation and interactions in rhodopsin: probing receptor activation by NMR spectroscopy. Biochimica Et Biophysica Acta. 1837: 683-93. PMID 24183693 DOI: 10.1016/j.bbabio.2013.10.007  0.44
2013 Opefi CA, South K, Reynolds CA, Smith SO, Reeves PJ. Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function. The Journal of Biological Chemistry. 288: 33912-26. PMID 24106275 DOI: 10.1074/jbc.M113.483032  1
2013 Xu B, Chakraborty R, Eilers M, Dakshinamurti S, O'Neil JD, Smith SO, Bhullar RP, Chelikani P. High-level expression, purification and characterization of a constitutively active thromboxane A2 receptor polymorphic variant. Plos One. 8: e76481. PMID 24086743 DOI: 10.1371/journal.pone.0076481  1
2013 Lin CP, Kim C, Smith SO, Neiman AM. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Plos Genetics. 9: e1003700. PMID 23966878 DOI: 10.1371/journal.pgen.1003700  1
2013 Kotarba AE, Aucoin D, Hoos MD, Smith SO, Van Nostrand WE. Fine mapping of the amyloid β-protein binding site on myelin basic protein. Biochemistry. 52: 2565-73. PMID 23510371 DOI: 10.1021/bi4001936  1
2013 Goncalves J, Eilers M, South K, Opefi CA, Laissue P, Reeves PJ, Smith SO. Magic angle spinning nuclear magnetic resonance spectroscopy of G protein-coupled receptors. Methods in Enzymology. 522: 365-89. PMID 23374193 DOI: 10.1016/B978-0-12-407865-9.00017-0  0.44
2013 Defour JP, Itaya M, Gryshkova V, Brett IC, Pecquet C, Sato T, Smith SO, Constantinescu SN. Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation. Proceedings of the National Academy of Sciences of the United States of America. 110: 2540-5. PMID 23359689 DOI: 10.1073/pnas.1211560110  1
2013 Matsushita C, Tamagaki H, Miyazawa Y, Aimoto S, Smith SO, Sato T. Transmembrane helix orientation influences membrane binding of the intracellular juxtamembrane domain in Neu receptor peptides. Proceedings of the National Academy of Sciences of the United States of America. 110: 1646-51. PMID 23319611 DOI: 10.1073/pnas.1215207110  0.32
2012 Eilers M, Goncalves JA, Ahuja S, Kirkup C, Hirshfeld A, Simmerling C, Reeves PJ, Sheves M, Smith SO. Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I. The Journal of Physical Chemistry. B. 116: 10477-89. PMID 22564141 DOI: 10.1021/jp3019183  1
2012 Ladiwala AR, Litt J, Kane RS, Aucoin DS, Smith SO, Ranjan S, Davis J, Van Nostrand WE, Tessier PM. Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity. The Journal of Biological Chemistry. 287: 24765-73. PMID 22547072 DOI: 10.1074/jbc.M111.329763  1
2012 Itaya M, Brett IC, Smith SO. Synthesis, purification, and characterization of single helix membrane peptides and proteins for NMR spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 831: 333-57. PMID 22167682 DOI: 10.1007/978-1-61779-480-3_18  1
2011 Staerk J, Defour JP, Pecquet C, Leroy E, Antoine-Poirel H, Brett I, Itaya M, Smith SO, Vainchenker W, Constantinescu SN. Orientation-specific signalling by thrombopoietin receptor dimers. The Embo Journal. 30: 4398-413. PMID 21892137 DOI: 10.1038/emboj.2011.315  1
2011 Arakawa M, Chakraborty R, Upadhyaya J, Eilers M, Reeves PJ, Smith SO, Chelikani P. Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor. Biochimica Et Biophysica Acta. 1808: 1170-8. PMID 21262196 DOI: 10.1016/j.bbamem.2011.01.012  0.44
2010 Goncalves JA, South K, Ahuja S, Zaitseva E, Opefi CA, Eilers M, Vogel R, Reeves PJ, Smith SO. Highly conserved tyrosine stabilizes the active state of rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 107: 19861-6. PMID 21041664 DOI: 10.1073/pnas.1009405107  0.84
2010 Liao MC, Hoos MD, Aucoin D, Ahmed M, Davis J, Smith SO, Van Nostrand WE. N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly. The Journal of Biological Chemistry. 285: 35590-8. PMID 20807757 DOI: 10.1074/jbc.M110.169599  1
2010 Goncalves JA, Ahuja S, Erfani S, Eilers M, Smith SO. Structure and function of G protein-coupled receptors using NMR spectroscopy. Progress in Nuclear Magnetic Resonance Spectroscopy. 57: 159-80. PMID 20633362 DOI: 10.1016/j.pnmrs.2010.04.004  0.84
2010 Khalifa NB, Van Hees J, Tasiaux B, Huysseune S, Smith SO, Constantinescu SN, Octave JN, Kienlen-Campard P. What is the role of amyloid precursor protein dimerization? Cell Adhesion & Migration. 4: 268-72. PMID 20400860  0.32
2010 Ahmed M, Davis J, Aucoin D, Sato T, Ahuja S, Aimoto S, Elliott JI, Van Nostrand WE, Smith SO. Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils. Nature Structural & Molecular Biology. 17: 561-7. PMID 20383142 DOI: 10.1038/nsmb.1799  1
2010 Hornak V, Ahuja S, Eilers M, Goncalves JA, Sheves M, Reeves PJ, Smith SO. Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints. Journal of Molecular Biology. 396: 510-27. PMID 20004206 DOI: 10.1016/j.jmb.2009.12.003  1
2009 Ahuja S, Eilers M, Hirshfeld A, Yan ECY, Ziliox M, Sakmar TP, Sheves M, Smith SO. 6-s-cis conformation and polar binding pocket of the retinal chromophore in the photoactivated state of rhodopsin Journal of the American Chemical Society. 131: 15160-15169. PMID 19795853 DOI: 10.1021/ja9034768  1
2009 Ahuja S, Smith SO. Multiple switches in G protein-coupled receptor activation. Trends in Pharmacological Sciences. 30: 494-502. PMID 19732972 DOI: 10.1016/j.tips.2009.06.003  0.84
2009 Liao MC, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purified myelin basic protein. The Journal of Biological Chemistry. 284: 28917-25. PMID 19692707 DOI: 10.1074/jbc.M109.050856  1
2009 Plo I, Zhang Y, Le Couédic JP, Nakatake M, Boulet JM, Itaya M, Smith SO, Debili N, Constantinescu SN, Vainchenker W, Louache F, de Botton S. An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia. The Journal of Experimental Medicine. 206: 1701-7. PMID 19620628 DOI: 10.1084/jem.20090693  1
2009 Sengupta P, Bosis E, Nachliel E, Gutman M, Smith SO, Mihályné G, Zaitseva I, McLaughlin S. EGFR juxtamembrane domain, membranes, and calmodulin: kinetics of their interaction. Biophysical Journal. 96: 4887-95. PMID 19527647 DOI: 10.1016/j.bpj.2009.03.027  1
2009 Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro. Biochemistry. 48: 4720-7. PMID 19385666 DOI: 10.1021/bi900037s  1
2009 Ahuja S, Hornak V, Yan ECY, Syrett N, Goncalves JA, Hirshfeld A, Ziliox M, Sakmar TP, Sheves M, Reeves PJ, Smith SO, Eilers M. Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation Nature Structural and Molecular Biology. 16: 168-175. PMID 19182802 DOI: 10.1038/nsmb.1549  1
2009 Ahuja S, Crocker E, Eilers M, Hornak V, Hirshfeld A, Ziliox M, Syrett N, Reeves PJ, Khorana HG, Sheves M, Smith SO. Location of the retinal chromophore in the activated state of rhodopsin*. The Journal of Biological Chemistry. 284: 10190-201. PMID 19176531 DOI: 10.1074/jbc.M805725200  1
2009 Sato T, Tang TC, Reubins G, Fei JZ, Fujimoto T, Kienlen-Campard P, Constantinescu SN, Octave JN, Aimoto S, Smith SO. A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 1421-6. PMID 19164538 DOI: 10.1073/pnas.0812261106  0.32
2009 Aucoin D, Camenares D, Zhao X, Jung J, Sato T, Smith SO. High-resolution 1H MAS RFDR NMR of biological membranes Journal of Magnetic Resonance. 197: 77-86. PMID 19121592 DOI: 10.1016/j.jmr.2008.12.009  1
2008 Kienlen-Campard P, Tasiaux B, Van Hees J, Li M, Huysseune S, Sato T, Fei JZ, Aimoto S, Courtoy PJ, Smith SO, Constantinescu SN, Octave JN. Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs. The Journal of Biological Chemistry. 283: 7733-44. PMID 18201969 DOI: 10.1074/jbc.M707142200  0.32
2007 Chelikani P, Hornak V, Eilers M, Reeves PJ, Smith SO, RajBhandary UL, Khorana HG. Role of group-conserved residues in the helical core of beta2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 7027-32. PMID 17438264 DOI: 10.1073/pnas.0702024104  1
2007 Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein. The Journal of Biological Chemistry. 282: 9952-61. PMID 17259179 DOI: 10.1074/jbc.M603494200  1
2006 Sato T, Pallavi P, Golebiewska U, McLaughlin S, Smith SO. Structure of the membrane reconstituted transmembrane-juxtamembrane peptide EGFR(622-660) and its interaction with Ca2+/calmodulin. Biochemistry. 45: 12704-14. PMID 17042488 DOI: 10.1021/bi061264m  1
2006 Sato T, Kienlen-Campard P, Ahmed M, Liu W, Li H, Elliott JI, Aimoto S, Constantinescu SN, Octave JN, Smith SO. Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. Biochemistry. 45: 5503-16. PMID 16634632 DOI: 10.1021/bi052485f  1
2006 Mastrangelo IA, Ahmed M, Sato T, Liu W, Wang C, Hough P, Smith SO. High-resolution atomic force microscopy of soluble Abeta42 oligomers. Journal of Molecular Biology. 358: 106-19. PMID 16499926 DOI: 10.1016/j.jmb.2006.01.042  0.32
2006 Seibert C, Ying W, Gavrilov S, Tsamis F, Kuhmann SE, Palani A, Tagat JR, Clader JW, McCombie SW, Baroudy BM, Smith SO, Dragic T, Moore JP, Sakmar TP. Interaction of small molecule inhibitors of HIV-1 entry with CCR5 Virology. 349: 41-54. PMID 16494916 DOI: 10.1016/j.virol.2006.01.018  1
2006 Crocker E, Eilers M, Ahuja S, Hornak V, Hirshfeld A, Sheves M, Smith SO. Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin. Journal of Molecular Biology. 357: 163-72. PMID 16414074 DOI: 10.1016/j.jmb.2005.12.046  1
2006 Staerk J, Lacout C, Sato T, Smith SO, Vainchenker W, Constantinescu SN. An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor. Blood. 107: 1864-71. PMID 16249382 DOI: 10.1182/blood-2005-06-2600  0.32
2005 Anderson LL, Marshall GR, Crocker E, Smith SO, Baranski TJ. Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits. The Journal of Biological Chemistry. 280: 31019-26. PMID 15983037 DOI: 10.1074/jbc.M503690200  1
2005 Eilers M, Hornak V, Smith SO, Konopka JB. Comparison of class A and D G protein-coupled receptors: common features in structure and activation. Biochemistry. 44: 8959-75. PMID 15966721 DOI: 10.1021/bi047316u  1
2005 McLaughlin S, Smith SO, Hayman MJ, Murray D. An electrostatic engine model for autoinhibition and activation of the epidermal growth factor receptor (EGFR/ErbB) family. The Journal of General Physiology. 126: 41-53. PMID 15955874 DOI: 10.1085/jgp.200509274  1
2005 Liu W, Crocker E, Constantinescu SN, Smith SO. Helix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus. Biophysical Journal. 89: 1194-202. PMID 15894629 DOI: 10.1529/biophysj.104.057844  0.44
2005 Patel AB, Crocker E, Reeves PJ, Getmanova EV, Eilers M, Khorana HG, Smith SO. Changes in interhelical hydrogen bonding upon rhodopsin activation. Journal of Molecular Biology. 347: 803-12. PMID 15769471 DOI: 10.1016/j.jmb.2005.01.069  0.44
2005 Howard KP, Liu W, Crocker E, Nanda V, Lear J, Degrado WF, Smith SO. Rotational orientation of monomers within a designed homo-oligomer transmembrane helical bundle. Protein Science : a Publication of the Protein Society. 14: 1019-24. PMID 15741331 DOI: 10.1110/ps.041110605  1
2005 Liu W, Crocker E, Zhang W, Elliott JI, Luy B, Li H, Aimoto S, Smith SO. Structural role of glycine in amyloid fibrils formed from transmembrane α-helices Biochemistry. 44: 3591-3597. PMID 15736968 DOI: 10.1021/bi047827g  1
2005 Kubatzky KF, Liu W, Goldgraben K, Simmerling C, Smith SO, Constantinescu SN. Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function. The Journal of Biological Chemistry. 280: 14844-54. PMID 15657048 DOI: 10.1074/jbc.M411251200  1
2004 Patel AB, Crocker E, Eilers M, Hirshfeld A, Sheves M, Smith SO. Coupling of retinal isomerization to the activation of rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 101: 10048-53. PMID 15220479 DOI: 10.1073/pnas.0402848101  1
2004 Gambhir A, Hangyás-Mihályné G, Zaitseva I, Cafiso DS, Wang J, Murray D, Pentyala SN, Smith SO, McLaughlin S. Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophysical Journal. 86: 2188-207. PMID 15041659 DOI: 10.1016/S0006-3495(04)74278-2  1
2004 Liu W, Eilers M, Patel AB, Smith SO. Helix Packing Moments Reveal Diversity and Conservation in Membrane Protein Structure Journal of Molecular Biology. 337: 713-729. PMID 15019789 DOI: 10.1016/j.jmb.2004.02.001  1
2004 Crocker E, Patel AB, Eilers M, Jayaraman S, Getmanova E, Reeves PJ, Ziliox M, Khorana HG, Sheves M, Smith SO. Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin. Journal of Biomolecular Nmr. 29: 11-20. PMID 15017136 DOI: 10.1023/B:JNMR.0000019521.79321.3c  1
2004 Getmanova E, Patel AB, Klein-Seetharaman J, Loewen MC, Reeves PJ, Friedman N, Sheves M, Smith SO, Khorana HG. NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation. Biochemistry. 43: 1126-33. PMID 14744159 DOI: 10.1021/bi030120u  1
2003 Seubert N, Royer Y, Staerk J, Kubatzky KF, Moucadel V, Krishnakumar S, Smith SO, Constantinescu SN. Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer. Molecular Cell. 12: 1239-50. PMID 14636581  0.32
2003 Zhang W, Crocker E, McLaughlin S, Smith SO. Binding of peptides with basic and aromatic residues to bilayer membranes: phenylalanine in the myristoylated alanine-rich C kinase substrate effector domain penetrates into the hydrophobic core of the bilayer. The Journal of Biological Chemistry. 278: 21459-66. PMID 12670959 DOI: 10.1074/jbc.M301652200  1
2003 Liu W, Crocker E, Siminovitch DJ, Smith SO. Role of side-chain conformational entropy in transmembrane helix dimerization of glycophorin A. Biophysical Journal. 84: 1263-71. PMID 12547806 DOI: 10.1016/S0006-3495(03)74941-8  0.44
2003 Lin JC, Parrish W, Eilers M, Smith SO, Konopka JB. Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled alpha-factor receptor. Biochemistry. 42: 293-301. PMID 12525156 DOI: 10.1021/bi026766o  1
2002 Irusta PM, Luo Y, Bakht O, Lai CC, Smith SO, DiMaio D. Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor. The Journal of Biological Chemistry. 277: 38627-34. PMID 12181311 DOI: 10.1074/jbc.M204890200  1
2002 Smith SO, Smith C, Shekar S, Peersen O, Ziliox M, Aimoto S. Transmembrane interactions in the activation of the Neu receptor tyrosine kinase Biochemistry. 41: 9321-9332. PMID 12135353 DOI: 10.1021/bi012117l  1
2002 Eilers M, Patel AB, Liu W, Smith SO. Comparison of helix interactions in membrane and soluble alpha-bundle proteins. Biophysical Journal. 82: 2720-36. PMID 11964258 DOI: 10.1016/S0006-3495(02)75613-0  0.44
2002 Smith SO, Eilers M, Song D, Crocker E, Ying W, Groesbeek M, Metz G, Ziliox M, Aimoto S. Implications of threonine hydrogen bonding in the glycophorin A transmembrane helix dimer. Biophysical Journal. 82: 2476-86. PMID 11964235 DOI: 10.1016/S0006-3495(02)75590-2  0.44
2002 Eilers M, Ying W, Reeves PJ, Khorana HG, Smith SO. Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin. Methods in Enzymology. 343: 212-22. PMID 11675791 DOI: 10.1016/S0076-6879(02)43137-0  0.44
2000 Dragic T, Trkola A, Thompson DA, Cormier EG, Kajumo FA, Maxwell E, Lin SW, Ying W, Smith SO, Sakmar TP, Moore JP. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proceedings of the National Academy of Sciences of the United States of America. 97: 5639-44. PMID 10779565 DOI: 10.1073/pnas.090576697  1
1999 Reeves PJ, Klein-Seetharaman J, Getmanova EV, Eilers M, Loewen MC, Smith SO, Khorana HG. Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies. Biochemical Society Transactions. 27: 950-5. PMID 10830134  1
1999 Javadpour MM, Eilers M, Groesbeek M, Smith SO. Helix packing in polytopic membrane proteins: role of glycine in transmembrane helix association. Biophysical Journal. 77: 1609-18. PMID 10465772 DOI: 10.1016/S0006-3495(99)77009-8  0.44
1999 Eilers M, Reeves PJ, Ying W, Khorana HG, Smith SO. Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line. Proceedings of the National Academy of Sciences of the United States of America. 96: 487-92. PMID 9892660 DOI: 10.1073/pnas.96.2.487  0.44
1998 Han M, Smith SO, Sakmar TP. Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6 Biochemistry. 37: 8253-8261. PMID 9609722 DOI: 10.1021/bi980147r  1
1998 Han M, Groesbeek M, Smith SO, Sakmar TP. Role of the C9 methyl group in rhodopsin activation: Characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal Biochemistry. 37: 538-545. PMID 9425074 DOI: 10.1021/bi972060w  1
1997 Han M, Groesbeek M, Sakmar TP, Smith SO. The C9 methyl group of retinal interacts with glycine-121 in rhodopsin Proceedings of the National Academy of Sciences of the United States of America. 94: 13442-13447. PMID 9391044 DOI: 10.1073/pnas.94.25.13442  1
1997 Han M, Lou J, Nakanishi K, Sakmar TP, Smith SO. Partial agonist activity of 11-cis-retinal in rhodopsin mutants Journal of Biological Chemistry. 272: 23081-23085. PMID 9287308 DOI: 10.1074/jbc.272.37.23081  1
1997 Shieh T, Han M, Sakmar TP, Smith SO. The steric trigger in rhodopsin activation Journal of Molecular Biology. 269: 373-384. PMID 9199406 DOI: 10.1006/jmbi.1997.1035  1
1996 Han M, Lin SW, Minkova M, Smith SO, Sakmar TP. Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant Journal of Biological Chemistry. 271: 32337-32342. PMID 8943296 DOI: 10.1074/jbc.271.50.32337  1
1996 Han M, Lin SW, Smith SO, Sakmar TP. The effects of amino acid replacements of glycine 121 on transmembrane helix 3 of rhodopsin Journal of Biological Chemistry. 271: 32330-32336. PMID 8943295 DOI: 10.1074/jbc.271.50.32330  1
1993 Farrar MR, Lakshmi KV, Smith SO, Brown RS, Raap J, Lugtenburg J, Griffin RG, Herzfeld J. Solid state NMR study of [epsilon-13C]Lys-bacteriorhodopsin: Schiff base photoisomerization. Biophysical Journal. 65: 310-5. PMID 8369438 DOI: 10.1016/S0006-3495(93)81065-8  1
1992 Smith SO, Peersen OB. Solid-state NMR approaches for studying membrane protein structure. Annual Review of Biophysics and Biomolecular Structure. 21: 25-47. PMID 1525470 DOI: 10.1146/annurev.bb.21.060192.000325  1
1992 Smith SO, de Groot H, Gebhard R, Lugtenburg J. Magic angle spinning NMR studies on the metarhodopsin II intermediate of bovine rhodopsin: evidence for an unprotonated Schiff base. Photochemistry and Photobiology. 56: 1035-9. PMID 1337211  1
1991 Smith SO, Courtin J, de Groot H, Gebhard R, Lugtenburg J. 13C magic-angle spinning NMR studies of bathorhodopsin, the primary photoproduct of rhodopsin. Biochemistry. 30: 7409-15. PMID 1649627  1
1990 Smith SO, Palings I, Miley ME, Courtin J, de Groot H, Lugtenburg J, Mathies RA, Griffin RG. Solid-state NMR studies of the mechanism of the opsin shift in the visual pigment rhodopsin. Biochemistry. 29: 8158-64. PMID 2261469  1
1990 de Groot HJ, Smith SO, Courtin J, van den Berg E, Winkel C, Lugtenburg J, Griffin RG, Herzfeld J. Solid-state 13C and 15N NMR study of the low pH forms of bacteriorhodopsin. Biochemistry. 29: 6873-83. PMID 2168744  1
1990 Herzfeld J, Das Gupta SK, Farrar MR, Harbison GS, McDermott AE, Pelletier SL, Raleigh DP, Smith SO, Winkel C, Lugtenburg J. Solid-state 13C NMR study of tyrosine protonation in dark-adapted bacteriorhodopsin. Biochemistry. 29: 5567-74. PMID 2167129  1
1989 Smith SO, Courtin J, van den Berg E, Winkel C, Lugtenburg J, Herzfeld J, Griffin RG. Solid-state 13C NMR of the retinal chromophore in photointermediates of bacteriorhodopsin: characterization of two forms of M. Biochemistry. 28: 237-43. PMID 2706247  1
1989 Smith SO, de Groot HJ, Gebhard R, Courtin JM, Lugtenburg J, Herzfeld J, Griffin RG. Structure and protein environment of the retinal chromophore in light- and dark-adapted bacteriorhodopsin studied by solid-state NMR. Biochemistry. 28: 8897-904. PMID 2605231  1
1987 Smith SO, Palings I, Copié V, Raleigh DP, Courtin J, Pardoen JA, Lugtenburg J, Mathies RA, Griffin RG. Low-temperature solid-state 13C NMR studies of the retinal chromophore in rhodopsin. Biochemistry. 26: 1606-11. PMID 3593680  1
1986 Smith SO, Hornung I, van der Steen R, Pardoen JA, Braiman MS, Lugtenburg J, Mathies RA. Are C14-C15 single bond isomerizations of the retinal chromophore involved in the proton-pumping mechanism of bacteriorhodopsin? Proceedings of the National Academy of Sciences of the United States of America. 83: 967-71. PMID 3006035  1
1985 Harbison GS, Smith SO, Pardoen JA, Courtin JM, Lugtenburg J, Herzfeld J, Mathies RA, Griffin RG. Solid-state 13C NMR detection of a perturbed 6-s-trans chromophore in bacteriorhodopsin. Biochemistry. 24: 6955-62. PMID 4074732  1
1985 Smith SO, Myers AB, Mathies RA, Pardoen JA, Winkel C, van den Berg EM, Lugtenburg J. Vibrational analysis of the all-trans retinal protonated Schiff base. Biophysical Journal. 47: 653-64. PMID 4016185 DOI: 10.1016/S0006-3495(85)83961-8  1
1985 Smith SO, Lugtenburg J, Mathies RA. Determination of retinal chromophore structure in bacteriorhodopsin with resonance Raman spectroscopy. The Journal of Membrane Biology. 85: 95-109. PMID 4009698  1
1985 Smith SO, Mathies RA. Resonance Raman spectra of the acidified and deionized forms of bacteriorhodopsin. Biophysical Journal. 47: 251-4. PMID 3978203  1
1984 Smith SO, Myers AB, Pardoen JA, Winkel C, Mulder PP, Lugtenburg J, Mathies R. Determination of retinal Schiff base configuration in bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 81: 2055-9. PMID 16593445  1
1984 Harbison GS, Smith SO, Pardoen JA, Winkel C, Lugtenburg J, Herzfeld J, Mathies R, Griffin RG. Dark-adapted bacteriorhodopsin contains 13-cis, 15-syn and all-trans, 15-anti retinal Schiff bases. Proceedings of the National Academy of Sciences of the United States of America. 81: 1706-9. PMID 6584904  1
1984 Smith SO, Marvin MJ, Bogomolni RA, Mathies RA. Structure of the retinal chromophore in the hR578 form of halorhodopsin Journal of Biological Chemistry. 259: 12326-12329. PMID 6490613  1
1984 Harbison GS, Smith SO, Pardoen JA, Mulder PP, Lugtenburg J, Herzfeld J, Mathies R, Griffin RG. Solid-state 13C NMR studies of retinal in bacteriorhodopsin. Biochemistry. 23: 2662-7. PMID 6466605  1
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