Duane Douglas Miller - Publications

Affiliations: 
1969-1992 Ohio State University, Columbus, OH, United States 
 1992- University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
design and synthesis of new drug molecules
Website:
https://www.acsmedchem.org/?nd=Miller

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ponnusamy S, He Y, Hwang DJ, Thiyagarajan T, Houtman R, Bocharova V, Sumpter BG, Fernandez E, Johnson DL, DU Z, Pfeffer LM, Getzenberg RH, McEwan IJ, Miller DD, Narayanan R. Orally-Bioavailable Androgen Receptor Degrader, A Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31481513 DOI: 10.1158/1078-0432.CCR-19-1458  1
2019 Wang Q, Arnst K, Wang Y, Kumar GK, Ma D, White SW, Miller DD, Li W, Li W. Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin. Journal of Medicinal Chemistry. PMID 31251599 DOI: 10.1021/acs.jmedchem.9b00706  1
2019 Arnst KE, Wang Y, Lei ZN, Hwang DJ, Kumar G, Ma D, Parke DN, Chen Q, Yang J, White SW, Seagroves TN, Chen ZS, Miller DD, Li W. Colchicine binding site agent DJ95 overcomes drug resistance and exhibits antitumor efficacy. Molecular Pharmacology. PMID 31043459 DOI: 10.1124/mol.118.114801  1
2019 Yang R, Chen H, Guo D, Dong Y, Miller DD, Li W, Mahato RI. Polymeric Micellar Delivery of Novel Microtubule Destabilizer and Hedgehog Signaling Inhibitor for Treating Chemoresistant Prostate Cancer. The Journal of Pharmacology and Experimental Therapeutics. PMID 30996033 DOI: 10.1124/jpet.119.256628  1
2019 Arnst KE, Banerjee S, Chen H, Deng S, Hwang DJ, Li W, Miller DD. Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy. Medicinal Research Reviews. PMID 30746734 DOI: 10.1002/med.21568  1
2019 Kashyap VK, Wang Q, Setua S, Nagesh PKB, Chauhan N, Kumari S, Chowdhury P, Miller DD, Yallapu MM, Li W, Jaggi M, Hafeez BB, Chauhan SC. Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer. Journal of Experimental & Clinical Cancer Research : Cr. 38: 29. PMID 30674344 DOI: 10.1186/s13046-018-1009-7  1
2018 Hwang DJ, He Y, Ponnusamy S, Mohler ML, Thiyagarajan T, McEwan IJ, Narayanan R, Miller DD. A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity. Journal of Medicinal Chemistry. PMID 30525603 DOI: 10.1021/acs.jmedchem.8b00973  1
2018 Wang Q, Arnst K, Wang Y, Kumar G, Ma D, Chen H, Wu Z, Yang J, White SW, Miller DD, Li W. Structural modification of the 3,4,5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities. Journal of Medicinal Chemistry. PMID 30122035 DOI: 10.1021/acs.jmedchem.8b00827  1
2018 Pi M, Kapoor K, Ye R, Hwang DJ, Miller DD, Smith JC, Baudry J, Quarles LD. Computationally identified novel agonists for GPRC6A. Plos One. 13: e0195980. PMID 29684031 DOI: 10.1371/journal.pone.0195980  1
2018 Wang Q, Arnst KE, Xue Y, Lei ZN, Ma D, Chen ZS, Miller DD, Li W. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. European Journal of Medicinal Chemistry. 149: 211-224. PMID 29501942 DOI: 10.1016/j.ejmech.2018.02.045  1
2018 Banerjee S, Arnst KE, Wang Y, Kumar G, Deng S, Yang L, Li GB, Yang J, White SW, Li W, Miller DD. Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Anti-Tumor Efficacy. Journal of Medicinal Chemistry. PMID 29406710 DOI: 10.1021/acs.jmedchem.7b01858  1
2018 Lin Z, Marepally SR, Goh ESY, Cheng CYS, Janjetovic Z, Kim TK, Miller DD, Postlethwaite AE, Slominski AT, Tuckey RC, Peluso-Iltis C, Rochel N, Li W. Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Scientific Reports. 8: 1478. PMID 29367669 DOI: 10.1038/s41598-018-19183-7  1
2017 Narayanan R, Ponnusamy S, Miller DD. Destroying the androgen receptor (AR)-potential strategy to treat advanced prostate cancer. Oncoscience. 4: 175-177. PMID 29344555 DOI: 10.18632/oncoscience.389  1
2017 Arnst KE, Wang Y, Hwang DJ, Xue Y, Costello T, Hamilton D, Chen Q, Yang J, Park F, Dalton JT, Miller DD, Li W. A potent, metabolically stable tubulin inhibitor targets the colchicine binding site and overcomes taxane resistance. Cancer Research. PMID 29180476 DOI: 10.1158/0008-5472.CAN-17-0577  1
2017 Ponnusamy S, Coss CC, Thiyagarajan T, Watts K, Hwang DJ, He Y, Selth LA, McEwan IJ, Duke CB, Pagadala J, Singh G, Wake RW, Ledbetter C, Tilley WD, Moldoveanu T, ... ... Miller DD, et al. Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer. Cancer Research. PMID 28978635 DOI: 10.1158/0008-5472.CAN-17-0976  1
2017 Park F, Miller D. Role of lysophosphatidic acid and its receptors in the kidney. Physiological Genomics. physiolgenomics.0007. PMID 28939644 DOI: 10.1152/physiolgenomics.00070.2017  0.04
2017 Lin Z, Chen H, Belorusova AY, Bollinger JC, Tang EKY, Janjetovic Z, Kim TK, Wu Z, Miller DD, Slominski AT, Postlethwaite AE, Tuckey RC, Rochel N, Li W. 1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis. Scientific Reports. 7: 10193. PMID 28860545 DOI: 10.1038/s41598-017-10917-7  1
2017 He H, Weir RL, Toutounchian JJ, Pagadala J, Steinle JJ, Baudry J, Miller DD, Yates CR. The quinic acid derivative KZ-41 prevents glucose-induced caspase-3 activation in retinal endothelial cells through an IGF-1 receptor dependent mechanism. Plos One. 12: e0180808. PMID 28796787 DOI: 10.1371/journal.pone.0180808  1
2017 Chen H, Lin Z, Arnst KE, Miller DD, Li W. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules (Basel, Switzerland). 22. PMID 28763044 DOI: 10.3390/molecules22081281  1
2017 Yang R, Mondal G, Ness RA, Arnst K, Mundra V, Miller DD, Li W, Mahato RI. Polymer conjugate of a microtubule destabilizer inhibits lung metastatic melanoma. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28130039 DOI: 10.1016/j.jconrel.2017.01.028  1
2017 Banerjee S, Norman DD, Lee SC, Parrill AL, Pham TC, Baker DL, Tigyi GG, Miller DD. Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. Journal of Medicinal Chemistry. PMID 28112925 DOI: 10.1021/acs.jmedchem.6b01270  1
2017 Ponnusamy S, Tran QT, Thiyagarajan T, Miller DD, Bridges D, Narayanan R. An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors. Experimental Biology and Medicine (Maywood, N.J.). 1535370216688569. PMID 28092182 DOI: 10.1177/1535370216688569  1
2017 Toutounchian JJ, Pagadala J, Miller DD, Baudry J, Park F, Chaum E, Yates CR. Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis. Molecular Pharmacology. 91: 1-13. PMID 27913654 DOI: 10.1124/mol.116.105031  1
2016 Banerjee S, Hwang DJ, Li W, Miller DD. Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis. Molecules (Basel, Switzerland). 21. PMID 27827858 DOI: 10.3390/molecules21111468  1
2016 Ponnusamy S, Tran QT, Harvey I, Smallwood HS, Thiyagarajan T, Banerjee S, Johnson DL, Dalton JT, Sullivan RD, Miller DD, Bridges D, Narayanan R. Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27733447 DOI: 10.1096/fj.201600787RR  1
2016 Lin Z, Marepally SR, Ma D, Kim TK, Oak AS, Myers LK, Tuckey RC, Slominski AT, Miller DD, Li W. Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R Epimer. Journal of Medicinal Chemistry. PMID 27070779 DOI: 10.1021/acs.jmedchem.6b00182  1
2016 Lin Z, Marepally SR, Kim TK, Janjetovic Z, Oak AS, Postlethwaite AE, Myers LK, Tuckey RC, Slominski AT, Miller DD, Li W. Design, Synthesis and Biological Activities of Novel Gemini 20S-Hydroxyvitamin D3 Analogs. Anticancer Research. 36: 877-86. PMID 26976974  1
2015 Pi M, Kapoor K, Wu Y, Ye R, Senogles SE, Nishimoto SK, Hwang DJ, Miller DD, Narayanan R, Smith JC, Baudry J, Quarles LD. Structural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral Tissues. Molecular Endocrinology (Baltimore, Md.). me20151161. PMID 26440882 DOI: 10.1210/me.2015-1161  1
2015 Wang Q, Lin Z, Kim TK, Slominski AT, Miller DD, Li W. Total synthesis of biologically active 20S-hydroxyvitamin D3. Steroids. PMID 26433048 DOI: 10.1016/j.steroids.2015.09.009  1
2015 Hwang DJ, Wang J, Li W, Miller DD. Structural Optimization of Indole Derivatives Acting at Colchicine Binding Site as Potential Anticancer Agents. Acs Medicinal Chemistry Letters. 6: 993-7. PMID 26396686 DOI: 10.1021/acsmedchemlett.5b00208  1
2015 Banerjee S, Wang J, Pfeffer S, Ma D, Pfeffer LM, Patil SA, Li W, Miller DD. Design, Synthesis and Biological Evaluation of Novel 5H-Chromenopyridines as Potential Anti-Cancer Agents. Molecules (Basel, Switzerland). 20: 17152-17165. PMID 26393554 DOI: 10.3390/molecules200917152  1
2015 Lin Z, Marepally SR, Ma D, Myers LK, Postlthwaite AE, Tuckey RC, Cheng CY, Kim TK, Yue J, Slominski AT, Miller DD, Li W. Chemical synthesis and biological activities of 20S,24S/R-dihydroxyvitamin D3 epimers and their 1α-hydroxyl derivatives. Journal of Medicinal Chemistry. PMID 26367019 DOI: 10.1021/acs.jmedchem.5b00881  1
2015 Rao P, Midde NM, Miller D, Chauhan S, Kumar A, Kumar S. Diallyl sulfide: Potential use in novel therapeutic interventions in alcohol, drugs, and disease mediated cellular toxicity by targeting cytochrome P450 2E1. Current Drug Metabolism. PMID 26264202  0.01
2015 Knowlden SA, Hillman SE, Chapman TJ, Patil R, Miller DD, Tigyi G, Georas SN. Novel Inhibitory Effect of an LPA2 Agonist on Allergen-driven Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. PMID 26248018 DOI: 10.1165/rcmb.2015-0124OC  1
2015 Ness RA, Miller DD, Li W. The role of vitamin D in cancer prevention. Chinese Journal of Natural Medicines. 13: 481-97. PMID 26233839 DOI: 10.1016/S1875-5364(15)30043-1  1
2015 Xiao M, Wang J, Lin Z, Lu Y, Li Z, White SW, Miller DD, Li W. Design, Synthesis and Structure-Activity Relationship Studies of Novel Survivin Inhibitors with Potent Anti-Proliferative Properties. Plos One. 10: e0129807. PMID 26070194 DOI: 10.1371/journal.pone.0129807  1
2015 Balogh A, Shimizu Y, Lee SC, Norman DD, Gangwar R, Bavaria M, Moon C, Shukla P, Rao R, Ray R, Naren AP, Banerje S, Miller DD, Balazs L, Pelus L, et al. The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair. Cellular Signalling. 27: 1751-62. PMID 26027517 DOI: 10.1016/j.cellsig.2015.05.015  1
2015 Mundra V, Peng Y, Kumar V, Li W, Miller DD, Mahato RI. Systemic delivery of nanoparticle formulation of novel tubulin inhibitor for treating metastatic melanoma. Drug Delivery and Translational Research. 5: 199-208. PMID 25924699 DOI: 10.1007/s13346-015-0226-2  1
2015 Deng W, Kimura Y, Gududuru V, Wu W, Balogh A, Szabo E, Thompson KE, Yates CR, Balazs L, Johnson LR, Miller DD, Strobos J, McCool WS, Tigyi GJ. Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid. Radiation Research. 183: 465-75. PMID 25807318 DOI: 10.1667/RR13830.1  1
2015 Patil R, Szabó E, Fells JI, Balogh A, Lim KG, Fujiwara Y, Norman DD, Lee SC, Balazs L, Thomas F, Patil S, Emmons-Thompson K, Boler A, Strobos J, McCool SW, ... ... Miller DD, et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chemistry & Biology. 22: 206-16. PMID 25619933 DOI: 10.1016/j.chembiol.2014.12.009  1
2015 Patil SA, Pfeffer SR, Seibel WL, Pfeffer LM, Miller DD. Identification of imidazoquinoline derivatives as potent antiglioma agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 11: 400-6. PMID 25219925  1
2015 Lee SC, Fujiwara Y, Liu J, Yue J, Shimizu Y, Norman DD, Wang Y, Tsukahara R, Szabo E, Patil R, Banerjee S, Miller DD, Balazs L, Ghosh MC, Waters CM, et al. Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis. Molecular Cancer Research : McR. 13: 174-85. PMID 25158955 DOI: 10.1158/1541-7786.MCR-14-0263  1
2014 Hosni-Ahmed A, Sims M, Jones TS, Patil R, Patil S, Abdelsamed H, Yates CR, Miller DD, Pfeffer LM. EDL-360: A Potential Novel Antiglioma Agent. Journal of Cancer Science & Therapy. 6: 370-377. PMID 25574358 DOI: 10.4172/1948-5956.1000295  1
2014 McMillan JE, Bukiya AN, Terrell CL, Patil SA, Miller DD, Dopico AM, Parrill AL. Multi-generational pharmacophore modeling for ligands to the cholane steroid-recognition site in the β₁ modulatory subunit of the BKCa channel. Journal of Molecular Graphics & Modelling. 54: 174-83. PMID 25459769 DOI: 10.1016/j.jmgm.2014.10.008  1
2014 Zawaski JA, Yates CR, Miller DD, Kaffes CC, Sabek OM, Afshar SF, Young DA, Yang Y, Gaber MW. Radiation combined injury models to study the effects of interventions and wound biomechanics. Radiation Research. 182: 640-52. PMID 25409125 DOI: 10.1667/RR13751.1  1
2014 Lu Y, Chen J, Wang J, Li CM, Ahn S, Barrett CM, Dalton JT, Li W, Miller DD. Design, synthesis, and biological evaluation of stable colchicine binding site tubulin inhibitors as potential anticancer agents. Journal of Medicinal Chemistry. 57: 7355-66. PMID 25122533 DOI: 10.1021/jm500764v  1
2014 Patil R, Fells JI, Szabó E, Lim KG, Norman DD, Balogh A, Patil S, Strobos J, Miller DD, Tigyi GJ. Design and synthesis of sulfamoyl benzoic acid analogues with subnanomolar agonist activity specific to the LPA2 receptor. Journal of Medicinal Chemistry. 57: 7136-40. PMID 25100502 DOI: 10.1021/jm5007116  1
2014 Jiang Y, Pagadala J, Miller DD, Steinle JJ. Insulin-like growth factor-1 binding protein 3 (IGFBP-3) promotes recovery from trauma-induced expression of inflammatory and apoptotic factors in retina. Cytokine. 70: 115-9. PMID 25082650 DOI: 10.1016/j.cyto.2014.07.004  1
2014 Chen J, Wang J, Schwab LP, Park KT, Seagroves TN, Jennings LK, Miller DD, Li W. Benzimidazole analogs as potent hypoxia inducible factor inhibitors: synthesis, biological evaluation, and profiling drug-like properties. Anticancer Research. 34: 3891-904. PMID 25075010  1
2014 Narayanan R, Ahn S, Cheney MD, Yepuru M, Miller DD, Steiner MS, Dalton JT. Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling. Plos One. 9: e103202. PMID 25072326 DOI: 10.1371/journal.pone.0103202  1
2014 Toutounchian JJ, Steinle JJ, Makena PS, Waters CM, Wilson MW, Haik BG, Miller DD, Yates CR. Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK. Plos One. 9: e100210. PMID 24956278 DOI: 10.1371/journal.pone.0100210  1
2014 Wen D, Chitkara D, Wu H, Danquah M, Patil R, Miller DD, Mahato RI. LHRH-conjugated micelles for targeted delivery of antiandrogen to treat advanced prostate cancer. Pharmaceutical Research. 31: 2784-95. PMID 24789451 DOI: 10.1007/s11095-014-1375-6  1
2014 Chen J, Wang J, Kim TK, Tieu EW, Tang EK, Lin Z, Kovacic D, Miller DD, Postlethwaite A, Tuckey RC, Slominski AT, Li W. Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity. Anticancer Research. 34: 2153-63. PMID 24778017  1
2014 Thompson KE, Zeng K, Wilson CM, Gaber MW, Miller DD, Yates CR. Quinic acid derivative KZ-41 exhibits radiomitigating activity in preclinical models of radiation injury. Drug Development Research. 75: 29-36. PMID 24648047 DOI: 10.1002/ddr.21164  1
2014 He H, Williams-Guy K, Pagadala J, Presley CS, Miller DD, Steinle JJ, Yates CR. A sensitive and fast LC-MS/MS method for determination of β-receptor agonist JP-49b: application to a pharmacokinetic study in rats. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 953: 86-91. PMID 24576769 DOI: 10.1016/j.jchromb.2014.01.031  1
2014 Patil R, Hosni-Ahmed A, Jones TS, Patil SA, Asres LB, Wang X, Yates RC, Geisert EE, Miller DD. Synthesis and in vitro evaluation of novel 1,2,3,4-tetrahydroisoquinoline derivatives as potent antiglioma agents. Anti-Cancer Agents in Medicinal Chemistry. 14: 473-82. PMID 24533653 DOI: 10.2174/18715206113139990328  1
2014 Fells JI, Lee SC, Norman DD, Tsukahara R, Kirby JR, Nelson S, Seibel W, Papoian R, Patil R, Miller DD, Parrill AL, Pham TC, Baker DL, Bittman R, Tigyi G. Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif. The Febs Journal. 281: 1017-28. PMID 24314137 DOI: 10.1111/febs.12674  1
2014 Wang J, Chen J, Miller DD, Li W. Synergistic combination of novel tubulin inhibitor ABI-274 and vemurafenib overcome vemurafenib acquired resistance in BRAFV600E melanoma. Molecular Cancer Therapeutics. 13: 16-26. PMID 24249714 DOI: 10.1158/1535-7163.MCT-13-0212  1
2013 Chen J, Slominski AT, Miller DD, Li W. Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D analogs determined by real-time NMR. Dermato-Endocrinology. 5: 142-9. PMID 24494047 DOI: 10.4161/derm.24339  1
2013 Slominski A, Kim TK, Zmijewski MA, Janjetovic Z, Li W, Chen J, Kusniatsova EI, Semak I, Postlethwaite A, Miller DD, Zjawiony JK, Tuckey RC. Novel vitamin D photoproducts and their precursors in the skin. Dermato-Endocrinology. 5: 7-19. PMID 24494038 DOI: 10.4161/derm.23938  1
2013 Narayanan R, Yepuru M, Coss CC, Wu Z, Bauler MN, Barrett CM, Mohler ML, Wang Y, Kim J, Snyder LM, He Y, Levy N, Miller DD, Dalton JT. Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation. Plos One. 8: e83380. PMID 24386191 DOI: 10.1371/journal.pone.0083380  1
2013 Patil SA, Patil R, Pfeffer LM, Miller DD. Chromenes: potential new chemotherapeutic agents for cancer. Future Medicinal Chemistry. 5: 1647-60. PMID 24047270 DOI: 10.4155/fmc.13.126  1
2013 Yepuru M, Wu Z, Kulkarni A, Yin F, Barrett CM, Kim J, Steiner MS, Miller DD, Dalton JT, Narayanan R. Steroidogenic enzyme AKR1C3 is a novel androgen receptor-selective coactivator that promotes prostate cancer growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5613-25. PMID 23995860 DOI: 10.1158/1078-0432.CCR-13-1151  1
2013 Zhang Q, Jiang Y, Toutounchian J, Wilson MW, Morales-Tirado V, Miller DD, Yates CR, Steinle JJ. Novel quinic acid derivative KZ-41 prevents retinal endothelial cell apoptosis without inhibiting retinoblastoma cell death through p38 signaling. Investigative Ophthalmology & Visual Science. 54: 5937-43. PMID 23942968 DOI: 10.1167/iovs.13-12326  1
2013 Jiang Y, Liu L, Pagadala J, Miller DD, Steinle JJ. Compound 49b protects against blast-induced retinal injury. Journal of Neuroinflammation. 10: 96. PMID 23899290 DOI: 10.1186/1742-2094-10-96  1
2013 Fells JI, Lee SC, Fujiwara Y, Norman DD, Lim KG, Tsukahara R, Liu J, Patil R, Miller DD, Kirby RJ, Nelson S, Seibel W, Papoian R, Parrill AL, Baker DL, et al. Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface. Molecular Pharmacology. 84: 415-24. PMID 23793291 DOI: 10.1124/mol.113.087080  1
2013 Patil SA, Hosni-Ahmed A, Jones TS, Patil R, Pfeffer LM, Miller DD. Novel approaches to glioma drug design and drug screening. Expert Opinion On Drug Discovery. 8: 1135-51. PMID 23738794 DOI: 10.1517/17460441.2013.807248  1
2013 Xiao M, Ahn S, Wang J, Chen J, Miller DD, Dalton JT, Li W. Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties. Journal of Medicinal Chemistry. 56: 3318-29. PMID 23547728 DOI: 10.1021/jm4001117  1
2013 Bukiya AN, McMillan JE, Fedinec AL, Patil SA, Miller DD, Leffler CW, Parrill AL, Dopico AM. Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent. Molecular Pharmacology. 83: 1030-44. PMID 23455312 DOI: 10.1124/mol.112.083519  1
2012 Patil SA, Patil R, Miller DD. Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents. Future Medicinal Chemistry. 4: 2085-115. PMID 23157240 DOI: 10.4155/fmc.12.141  1
2012 Mundra V, Lu Y, Danquah M, Li W, Miller DD, Mahato RI. Formulation and characterization of polyester/polycarbonate nanoparticles for delivery of a novel microtubule destabilizing agent. Pharmaceutical Research. 29: 3064-74. PMID 23054088 DOI: 10.1007/s11095-012-0881-7  1
2012 Kiss GN, Fells JI, Gupte R, Lee SC, Liu J, Nusser N, Lim KG, Ray RM, Lin FT, Parrill AL, Sümegi B, Miller DD, Tigyi G. Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions. Molecular Pharmacology. 82: 1162-73. PMID 22968304 DOI: 10.1124/mol.112.079699  1
2012 Bukiya AN, Patil SA, Li W, Miller DD, Dopico AM. Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain. Chemmedchem. 7: 1784-92. PMID 22945504 DOI: 10.1002/cmdc.201200290  1
2012 Lu Y, Chen J, Xiao M, Li W, Miller DD. An overview of tubulin inhibitors that interact with the colchicine binding site. Pharmaceutical Research. 29: 2943-71. PMID 22814904 DOI: 10.1007/s11095-012-0828-z  1
2012 Chen J, Ahn S, Wang J, Lu Y, Dalton JT, Miller DD, Li W. Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents. Journal of Medicinal Chemistry. 55: 7285-9. PMID 22783954 DOI: 10.1021/jm300564b  1
2012 Li CM, Lu Y, Chen J, Costello TA, Narayanan R, Dalton MN, Snyder LM, Ahn S, Li W, Miller DD, Dalton JT. Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer. Pharmaceutical Research. 29: 3053-63. PMID 22760659 DOI: 10.1007/s11095-012-0814-5  1
2012 Giddabasappa A, Eswaraka JR, Barrett CM, Bauler MN, Wu Z, Yepuru M, Miller DD, Dalton JT. β-LGND2, an ERβ selective agonist, inhibits pathologic retinal neovascularization. Investigative Ophthalmology & Visual Science. 53: 5066-75. PMID 22714897 DOI: 10.1167/iovs.12-9627  1
2012 Patil SA, Wang J, Li XS, Chen J, Jones TS, Hosni-Ahmed A, Patil R, Seibel WL, Li W, Miller DD. New substituted 4H-chromenes as anticancer agents. Bioorganic & Medicinal Chemistry Letters. 22: 4458-61. PMID 22608389 DOI: 10.1016/j.bmcl.2012.04.074  1
2012 Mohler ML, Coss CC, Duke CB, Patil SA, Miller DD, Dalton JT. Androgen receptor antagonists: a patent review (2008-2011). Expert Opinion On Therapeutic Patents. 22: 541-65. PMID 22583332 DOI: 10.1517/13543776.2012.682571  1
2012 Yang J, Ahn S, Wu Z, Hwang DJ, Miller DD, Dalton JT. Pharmacokinetics, pharmacodynamics and metabolism of a novel anticancer agent for prostate cancer. International Journal of Oncology. 41: 337-44. PMID 22576690 DOI: 10.3892/ijo.2012.1442  1
2012 Zhang Q, Guy K, Pagadala J, Jiang Y, Walker RJ, Liu L, Soderland C, Kern TS, Ferry R, He H, Yates CR, Miller DD, Steinle JJ. Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levels. Investigative Ophthalmology & Visual Science. 53: 3004-13. PMID 22467575 DOI: 10.1167/iovs.11-8779  1
2012 Danquah M, Duke CB, Patil R, Miller DD, Mahato RI. Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer. Pharmaceutical Research. 29: 2079-91. PMID 22451249 DOI: 10.1007/s11095-012-0737-1  1
2012 Wang Z, Chen J, Wang J, Ahn S, Li CM, Lu Y, Loveless VS, Dalton JT, Miller DD, Li W. Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis. Pharmaceutical Research. 29: 3040-52. PMID 22410804 DOI: 10.1007/s11095-012-0726-4  1
2012 Lu Y, Chen J, Janjetovic Z, Michaels P, Tang EK, Wang J, Tuckey RC, Slominski AT, Li W, Miller DD. Design, synthesis, and biological action of 20R-hydroxyvitamin D3. Journal of Medicinal Chemistry. 55: 3573-7. PMID 22404326 DOI: 10.1021/jm201478e  1
2012 Wang XD, Freeman NE, Patil R, Patil SA, Mitra S, Orr WE, Abner CW, Yates CR, Miller DD, Geisert EE. EDL-291, a novel isoquinoline, presents antiglioblastoma effects in vitro and in vivo. Anti-Cancer Drugs. 23: 494-504. PMID 22391460 DOI: 10.1097/CAD.0b013e328351ee4f  1
2012 Coss CC, Jones A, Parke DN, Narayanan R, Barrett CM, Kearbey JD, Veverka KA, Miller DD, Morton RA, Steiner MS, Dalton JT. Preclinical characterization of a novel diphenyl benzamide selective ERα agonist for hormone therapy in prostate cancer. Endocrinology. 153: 1070-81. PMID 22294742 DOI: 10.1210/en.2011-1608  1
2012 Gotoh M, Fujiwara Y, Yue J, Liu J, Lee S, Fells J, Uchiyama A, Murakami-Murofushi K, Kennel S, Wall J, Patil R, Gupte R, Balazs L, Miller DD, Tigyi GJ. Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis. Biochemical Society Transactions. 40: 31-6. PMID 22260662 DOI: 10.1042/BST20110608  1
2012 Coss CC, Bauler M, Narayanan R, Miller DD, Dalton JT. Alanine aminotransferase regulation by androgens in non-hepatic tissues. Pharmaceutical Research. 29: 1046-56. PMID 22167351 DOI: 10.1007/s11095-011-0649-5  1
2011 Zeng K, Thompson KE, Presley CS, Miller DD, Yates CR. Preclinical pharmacokinetics of the radiomitigator KZ-41 in rats. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 1006-12. PMID 21864202 DOI: 10.3109/00498254.2011.603387  1
2011 Chen J, Li CM, Wang J, Ahn S, Wang Z, Lu Y, Dalton JT, Miller DD, Li W. Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization. Bioorganic & Medicinal Chemistry. 19: 4782-95. PMID 21775150 DOI: 10.1016/j.bmc.2011.06.084  1
2011 Li CM, Chen J, Lu Y, Narayanan R, Parke DN, Li W, Ahn S, Miller DD, Dalton JT. Pharmacokinetic optimization of 4-substituted methoxybenzoyl-aryl-thiazole and 2-aryl-4-benzoyl-imidazole for improving oral bioavailability. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1833-9. PMID 21742898 DOI: 10.1124/dmd.110.036616  1
2011 Lu Y, Li CM, Wang Z, Chen J, Mohler ML, Li W, Dalton JT, Miller DD. Design, synthesis, and SAR studies of 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents. Journal of Medicinal Chemistry. 54: 4678-93. PMID 21557538 DOI: 10.1021/jm2003427  1
2011 Duke CB, Jones A, Bohl CE, Dalton JT, Miller DD. Unexpected binding orientation of bulky-B-ring anti-androgens and implications for future drug targets. Journal of Medicinal Chemistry. 54: 3973-6. PMID 21506597 DOI: 10.1021/jm2000097  1
2011 Gupte R, Patil R, Liu J, Wang Y, Lee SC, Fujiwara Y, Fells J, Bolen AL, Emmons-Thompson K, Yates CR, Siddam A, Panupinthu N, Pham TC, Baker DL, Parrill AL, ... Miller DD, et al. Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. Chemmedchem. 6: 922-35. PMID 21465666 DOI: 10.1002/cmdc.201000425  1
2011 Ahn S, Kearbey JD, Li CM, Duke CB, Miller DD, Dalton JT. Biotransformation of a novel antimitotic agent, I-387, by mouse, rat, dog, monkey, and human liver microsomes and in vivo pharmacokinetics in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 636-43. PMID 21233217 DOI: 10.1124/dmd.110.036673  1
2011 Patil SA, Patil R, Miller DD. Microwave-assisted synthesis of medicinally relevant indoles Current Medicinal Chemistry. 18: 615-637. PMID 21143107 DOI: 10.2174/092986711794480195  1
2011 Li CM, Wang Z, Lu Y, Ahn S, Narayanan R, Kearbey JD, Parke DN, Li W, Miller DD, Dalton JT. Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitor. Cancer Research. 71: 216-24. PMID 21084278 DOI: 10.1158/0008-5472.CAN-10-1725  1
2011 Zmijewski MA, Li W, Chen J, Kim TK, Zjawiony JK, Sweatman TW, Miller DD, Slominski AT. Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity. Steroids. 76: 193-203. PMID 21070794 DOI: 10.1016/j.steroids.2010.10.009  1
2011 Ahn S, Hwang DJ, Barrett CM, Yang J, Duke CB, Miller DD, Dalton JT. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer. Cancer Chemotherapy and Pharmacology. 67: 293-304. PMID 20383708 DOI: 10.1007/s00280-010-1319-8  1
2010 Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD. Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Bioorganic & Medicinal Chemistry Letters. 20: 7525-8. PMID 21051230 DOI: 10.1016/j.bmcl.2010.09.115  1
2010 Narayanan R, Jiang J, Gusev Y, Jones A, Kearbey JD, Miller DD, Schmittgen TD, Dalton JT. MicroRNAs are mediators of androgen action in prostate and muscle. Plos One. 5: e13637. PMID 21048966 DOI: 10.1371/journal.pone.0013637  1
2010 Chen J, Wang Z, Li CM, Lu Y, Vaddady PK, Meibohm B, Dalton JT, Miller DD, Li W. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. Journal of Medicinal Chemistry. 53: 7414-27. PMID 20919720 DOI: 10.1021/jm100884b  1
2010 Ahn S, Duke CB, Barrett CM, Hwang DJ, Li CM, Miller DD, Dalton JT. I-387, a novel antimitotic indole, displays a potent in vitro and in vivo antitumor activity with less neurotoxicity. Molecular Cancer Therapeutics. 9: 2859-68. PMID 20829196 DOI: 10.1158/1535-7163.MCT-10-0399  1
2010 Li CM, Lu Y, Ahn S, Narayanan R, Miller DD, Dalton JT. Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin. Journal of Mass Spectrometry : Jms. 45: 1160-6. PMID 20814887 DOI: 10.1002/jms.1804  1
2010 Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways. International Journal of Oncology. 37: 1023-30. PMID 20811725  1
2010 Kosanam H, Ma F, He H, Ramagiri S, Gududuru V, Tigyi GJ, Van Rompay K, Miller DD, Yates CR. Development of an LC-MS/MS assay to determine plasma pharmacokinetics of the radioprotectant octadecenyl thiophosphate (OTP) in monkeys. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 2379-83. PMID 20719582 DOI: 10.1016/j.jchromb.2010.07.004  1
2010 Li CM, Lu Y, Narayanan R, Miller DD, Dalton JT. Drug metabolism and pharmacokinetics of 4-substituted methoxybenzoyl-aryl-thiazoles. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2032-9. PMID 20675405 DOI: 10.1124/dmd.110.034348  1
2010 Yepuru M, Eswaraka J, Kearbey JD, Barrett CM, Raghow S, Veverka KA, Miller DD, Dalton JT, Narayanan R. Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice. The Journal of Biological Chemistry. 285: 31292-303. PMID 20657011 DOI: 10.1074/jbc.M110.147850  1
2010 Nassr M, Wang X, Mitra S, Freeman-Anderson NE, Patil R, Yates CR, Miller DD, Geisert EE. Treating retinoblastoma in tissue culture and in a rat model with a novel isoquinoline derivative. Investigative Ophthalmology & Visual Science. 51: 3813-9. PMID 20570997 DOI: 10.1167/iovs.09-5042  1
2010 Giddabasappa A, Bauler MN, Barrett CM, Coss CC, Wu Z, Miller DD, Dalton JT, Eswaraka JR. GTx-822, an ER{beta}-selective agonist, protects retinal pigment epithelium (ARPE-19) from oxidative stress by activating MAPK and PI3-K pathways. Investigative Ophthalmology & Visual Science. 51: 5934-42. PMID 20554624 DOI: 10.1167/iovs.10-5630  1
2010 Jones A, Hwang DJ, Narayanan R, Miller DD, Dalton JT. Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy. Endocrinology. 151: 3706-19. PMID 20534726 DOI: 10.1210/en.2010-0150  1
2010 Jones A, Hwang DJ, Duke CB, He Y, Siddam A, Miller DD, Dalton JT. Nonsteroidal selective androgen receptor modulators enhance female sexual motivation. The Journal of Pharmacology and Experimental Therapeutics. 334: 439-48. PMID 20444881 DOI: 10.1124/jpet.110.168880  1
2010 Li F, Lu Y, Li W, Miller DD, Mahato RI. Synthesis, formulation and in vitro evaluation of a novel microtubule destabilizer, SMART-100. Journal of Controlled Release : Official Journal of the Controlled Release Society. 143: 151-8. PMID 20060430 DOI: 10.1016/j.jconrel.2009.12.028  1
2010 Lu Y, Wang Z, Li CM, Chen J, Dalton JT, Li W, Miller DD. Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents. Bioorganic & Medicinal Chemistry. 18: 477-95. PMID 20056548 DOI: 10.1016/j.bmc.2009.12.020  1
2009 Zeng K, Thompson KE, Yates CR, Miller DD. Synthesis and biological evaluation of quinic acid derivatives as anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters. 19: 5458-60. PMID 19674895 DOI: 10.1016/j.bmcl.2009.07.096  1
2009 Patil SA, Patil R, Miller DD. Solid phase synthesis of biologically important indoles. Current Medicinal Chemistry. 16: 2531-65. PMID 19601797 DOI: 10.2174/092986709788682010  1
2009 Wang Z, Lu Y, Seibel W, Miller DD, Li W. Identifying novel molecular structures for advanced melanoma by ligand-based virtual screening. Journal of Chemical Information and Modeling. 49: 1420-7. PMID 19445498 DOI: 10.1021/ci800445a  1
2009 Mohler ML, Bohl CE, Jones A, Coss CC, Narayanan R, He Y, Hwang DJ, Dalton JT, Miller DD. Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. Journal of Medicinal Chemistry. 52: 3597-617. PMID 19432422 DOI: 10.1021/jm900280m  1
2009 Lu Y, Li CM, Wang Z, Ross CR, Chen J, Dalton JT, Li W, Miller DD. Discovery of 4-substituted methoxybenzoyl-aryl-thiazole as novel anticancer agents: synthesis, biological evaluation, and structure-activity relationships. Journal of Medicinal Chemistry. 52: 1701-11. PMID 19243174 DOI: 10.1021/jm801449a  1
2009 Ramagiri S, Ma F, Kosanam H, Wang X, Patil R, Miller DD, Geisert E, Yates CR. Fast and sensitive liquid chromatography/electrospray mass spectrometry method to study ocular penetration of EDL-155, a novel antitumor agent for retinoblastoma in rats Journal of Mass Spectrometry. 44: 786-793. PMID 19160451 DOI: 10.1002/jms.1556  1
2009 Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells. Steroids. 74: 218-28. PMID 19028513 DOI: 10.1016/j.steroids.2008.10.017  1
2009 Jones A, Chen J, Hwang DJ, Miller DD, Dalton JT. Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology. 150: 385-95. PMID 18772237 DOI: 10.1210/en.2008-0674  1
2009 Li W, Hwang DJ, Cremer D, Joo H, Kraka E, Kim J, Ross CR, Nguyen VQ, Dalton JT, Miller DD. Structure determination of chiral sulfoxide in diastereomeric bicalutamide derivatives. Chirality. 21: 578-83. PMID 18726944 DOI: 10.1002/chir.20642  1
2008 Narayanan R, Mohler ML, Bohl CE, Miller DD, Dalton JT. Selective androgen receptor modulators in preclinical and clinical development. Nuclear Receptor Signaling. 6: e010. PMID 19079612 DOI: 10.1621/nrs.06010  1
2008 Zhu L, Lu Y, Miller DD, Mahato RI. Structural and formulation factors influencing pyridinium lipid-based gene transfer. Bioconjugate Chemistry. 19: 2499-512. PMID 19053309 DOI: 10.1021/bc8004039  1
2008 Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 7: 1570-6. PMID 19037511 DOI: 10.1039/b809005j  1
2008 DeCuypere M, Lu Y, Miller DD, LeDoux MS. Regional distribution of tetrahydroisoquinoline derivatives in rodent, human, and Parkinson's disease brain. Journal of Neurochemistry. 107: 1398-413. PMID 19013830 DOI: 10.1111/j.1471-4159.2008.05709.x  1
2008 Bohl CE, Wu Z, Chen J, Mohler ML, Yang J, Hwang DJ, Mustafa S, Miller DD, Bell CE, Dalton JT. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorganic & Medicinal Chemistry Letters. 18: 5567-70. PMID 18805694 DOI: 10.1016/j.bmcl.2008.09.002  1
2008 Kang GS, Wang XD, Mohler ML, Kirichenko OV, Patil R, Orr WE, Miller DD, Geisert EE. Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma. Anti-Cancer Drugs. 19: 859-70. PMID 18766000 DOI: 10.1097/CAD.0b013e32830d5887  1
2008 Chen J, Wang Z, Lu Y, Dalton JT, Miller DD, Li W. Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma. Bioorganic & Medicinal Chemistry Letters. 18: 3183-7. PMID 18477505 DOI: 10.1016/j.bmcl.2008.04.073  1
2008 DeCuypere M, Kalabokis VN, Hao R, Schroeder D, Miller DD, LeDoux MS. Localization of N-methyl-norsalsolinol within rodent and human brain. Journal of Neuroscience Research. 86: 2543-52. PMID 18438936 DOI: 10.1002/jnr.21691  1
2007 Kosanam H, Prakash PK, Yates CR, Miller DD, Ramagiri S. Rapid screening of doping agents in human urine by vacuum MALDI-linear ion trap mass spectrometry. Analytical Chemistry. 79: 6020-6. PMID 17602668 DOI: 10.1021/ac070118z  1
2007 Li W, Lu Y, Wang Z, Dalton JT, Miller DD. Synthesis and antiproliferative activity of thiazolidine analogs for melanoma. Bioorganic & Medicinal Chemistry Letters. 17: 4113-7. PMID 17561392 DOI: 10.1016/j.bmcl.2007.05.059  1
2007 Li W, Wang Z, Gududuru V, Zbytek B, Slominski AT, Dalton JT, Miller DD. Structure-activity relationship studies of arylthiazolidine amides as selective cytotoxic agents for melanoma. Anticancer Research. 27: 883-8. PMID 17465215  1
2007 Bohl CE, Wu Z, Miller DD, Bell CE, Dalton JT. Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design. The Journal of Biological Chemistry. 282: 13648-55. PMID 17311914 DOI: 10.1074/jbc.M611711200  1
2006 Mohler ML, Kang GS, Hong SS, Patil R, Kirichenko OV, Li W, Rakov IM, Geisert EE, Miller DD. Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues. Journal of Medicinal Chemistry. 49: 5845-8. PMID 16970409 DOI: 10.1021/jm060020x  1
2006 Hwang DJ, Yang J, Xu H, Rakov IM, Mohler ML, Dalton JT, Miller DD. Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer. Bioorganic & Medicinal Chemistry. 14: 6525-38. PMID 16828557 DOI: 10.1016/j.bmc.2006.06.019  1
2006 Perera MA, Yin D, Wu D, Chan KK, Miller DD, Dalton J. In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1713-21. PMID 16815963 DOI: 10.1124/dmd.106.009985  1
2006 Nikulin VI, Rakov IM, De Los Angeles JE, Mehta RC, Boyd LY, Feller DR, Miller DD. 1-Benzyl-1,2,3,4-tetrahydroisoquinoline-6,7-diols as novel affinity and photoaffinity probes for beta-adrenoceptor subtypes. Bioorganic & Medicinal Chemistry. 14: 1684-97. PMID 16431119 DOI: 10.1016/j.bmc.2005.12.027  1
2006 Wu D, Wu Z, Yang J, Nair VA, Miller DD, Dalton JT. Pharmacokinetics and metabolism of a selective androgen receptor modulator in rats: Implication of molecular properties and intensive metabolic profile to investigate ideal pharmacokinetic characteristics of a propanamide in preclinical study Drug Metabolism and Disposition. 34: 483-494. PMID 16381665 DOI: 10.1124/dmd.105.006643.  1
2006 Gududuru V, Zeng K, Tsukahara R, Makarova N, Fujiwara Y, Pigg KR, Baker DL, Tigyi G, Miller DD. Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors. Bioorganic & Medicinal Chemistry Letters. 16: 451-6. PMID 16290140 DOI: 10.1016/j.bmcl.2005.08.096  1
2006 Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD. Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. Bioorganic & Medicinal Chemistry Letters. 16: 633-40. PMID 16263282 DOI: 10.1016/j.bmcl.2005.10.031  1
2005 Chen J, Hwang DJ, Chung K, Bohl CE, Fisher SJ, Miller DD, Dalton JT. In vitro and in vivo structure-activity relationships of novel androgen receptor ligands with multiple substituents in the B-ring. Endocrinology. 146: 5444-54. PMID 16166218 DOI: 10.1210/en.2005-0732  1
2005 Bohl CE, Miller DD, Chen J, Bell CE, Dalton JT. Structural basis for accommodation of nonsteroidal ligands in the androgen receptor. The Journal of Biological Chemistry. 280: 37747-54. PMID 16129672 DOI: 10.1074/jbc.M507464200  1
2005 Durgam GG, Virag T, Walker MD, Tsukahara R, Yasuda S, Liliom K, van Meeteren LA, Moolenaar WH, Wilke N, Siess W, Tigyi G, Miller DD. Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. Journal of Medicinal Chemistry. 48: 4919-30. PMID 16033271 DOI: 10.1021/jm049609r  1
2005 Gududuru V, Hurh E, Sullivan J, Dalton JT, Miller DD. SAR studies of 2-arylthiazolidine-4-carboxylic acid amides: a novel class of cytotoxic agents for prostate cancer. Bioorganic & Medicinal Chemistry Letters. 15: 4010-3. PMID 16005217 DOI: 10.1016/j.bmcl.2005.06.032  1
2005 Mustafa SM, Bavadekar SA, Ma G, Moore BM, Feller DR, Miller DD. Synthesis and biological studies of yohimbine derivatives on human alpha2C-adrenergic receptors. Bioorganic & Medicinal Chemistry Letters. 15: 2758-60. PMID 15911252 DOI: 10.1016/j.bmcl.2005.03.116  1
2005 Bohl CE, Gao W, Miller DD, Bell CE, Dalton JT. Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 102: 6201-6. PMID 15833816 DOI: 10.1073/pnas.0500381102  1
2005 Gududuru V, Hurh E, Dalton JT, Miller DD. Discovery of 2-arylthiazolidine-4-carboxylic acid amides as a new class of cytotoxic agents for prostate cancer. Journal of Medicinal Chemistry. 48: 2584-8. PMID 15801848 DOI: 10.1021/jm049208b  1
2005 Narang AS, Thoma L, Miller DD, Mahato RI. Cationic lipids with increased DNA binding affinity for nonviral gene transfer in dividing and nondividing cells. Bioconjugate Chemistry. 16: 156-68. PMID 15656587 DOI: 10.1021/bc049818q  1
2004 Gududuru V, Hurh E, Dalton JT, Miller DD. Synthesis and antiproliferative activity of 2-aryl-4-oxo-thiazolidin-3-yl-amides for prostate cancer. Bioorganic & Medicinal Chemistry Letters. 14: 5289-93. PMID 15454213 DOI: 10.1016/j.bmcl.2004.08.029  1
2004 Gududuru V, Hurh E, Durgam GG, Hong SS, Sardar VM, Xu H, Dalton JT, Miller DD. Synthesis and biological evaluation of novel cytotoxic phospholipids for prostate cancer. Bioorganic & Medicinal Chemistry Letters. 14: 4919-23. PMID 15341952 DOI: 10.1016/j.bmcl.2004.07.026  1
2004 Gao W, Kearbey JD, Nair VA, Chung K, Parlow AF, Miller DD, Dalton JT. Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5α-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: New approach for benign prostate hyperplasia Endocrinology. 145: 5420-5428. PMID 15308613 DOI: 10.1210/en.2004-0627  1
2004 Bohl CE, Chang C, Mohler ML, Chen J, Miller DD, Swaan PW, Dalton JT. A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor. Journal of Medicinal Chemistry. 47: 3765-76. PMID 15239655 DOI: 10.1021/jm0499007  1
2004 Marhefka CA, Gao W, Chung K, Kim J, He Y, Yin D, Bohl C, Dalton JT, Miller DD. Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators. Journal of Medicinal Chemistry. 47: 993-8. PMID 14761201 DOI: 10.1021/jm030336u  1
2004 Wu Z, Gao W, Phelps MA, Wu D, Miller DD, Dalton JT. Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry. Analytical Chemistry. 76: 839-47. PMID 14750883 DOI: 10.1021/ac0351670  1
2003 Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW. Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharmaceutical Research. 20: 1794-803. PMID 14661924  1
2003 Virag T, Elrod DB, Liliom K, Sardar VM, Parrill AL, Yokoyama K, Durgam G, Deng W, Miller DD, Tigyi G. Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors. Molecular Pharmacology. 63: 1032-42. PMID 12695531 DOI: 10.1124/mol.63.5.1032  1
2003 Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT. Pharmacodynamics of selective androgen receptor modulators. The Journal of Pharmacology and Experimental Therapeutics. 304: 1334-40. PMID 12604714 DOI: 10.1124/jpet.102.040840  1
2003 Yin D, Xu H, He Y, Kirkovsky LI, Miller DD, Dalton JT. Pharmacology, pharmacokinetics, and metabolism of acetothiolutamide, a novel nonsteroidal agonist for the androgen receptor. The Journal of Pharmacology and Experimental Therapeutics. 304: 1323-33. PMID 12604713 DOI: 10.1124/jpet.102.040832  1
2003 Yin D, He Y, Perera MA, Hong SS, Marhefka C, Stourman N, Kirkovsky L, Miller DD, Dalton JT. Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor. Molecular Pharmacology. 63: 211-23. PMID 12488554 DOI: 10.1124/mol.63.1.211  1
2002 Wang DA, Narang AS, Kotb M, Gaber AO, Miller DD, Kim SW, Mahato RI. Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery. Biomacromolecules. 3: 1197-207. PMID 12425656  1
2002 He Y, Yin D, Perera M, Kirkovsky L, Stourman N, Li W, Dalton JT, Miller DD. Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor. European Journal of Medicinal Chemistry. 37: 619-34. PMID 12161060  1
2001 Donkor IO, Zheng X, Han J, Lacy C, Miller DD. Significance of hydrogen bonding at the S(1)' subsite of calpain I. Bioorganic & Medicinal Chemistry Letters. 11: 1753-5. PMID 11425553  1
2001 Marhefka CA, Moore BM, Bishop TC, Kirkovsky L, Mukherjee A, Dalton JT, Miller DD. Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands Journal of Medicinal Chemistry. 44: 1729-1740. PMID 11356108 DOI: 10.1021/jm0005353  1
2001 Baker DL, Desiderio DM, Miller DD, Tolley B, Tigyi GJ. Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry. Analytical Biochemistry. 292: 287-95. PMID 11355863 DOI: 10.1006/abio.2001.5063  1
2001 Liliom K, Sun G, Bünemann M, Virág T, Nusser N, Baker DL, Wang DA, Fabian MJ, Brandts B, Bender K, Eickel A, Malik KU, Miller DD, Desiderio DM, Tigyi G, et al. Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors. The Biochemical Journal. 355: 189-97. PMID 11256963 DOI: 10.1042/0264-6021:3550189  1
2001 Konkar AA, Nikulin VI, De Los Angeles J, Hong SS, Fertel RH, Miller DD, Feller DR. Biochemical activities of trimetoquinol analogs at human beta(1)- and beta(3)-adrenergic receptors. Pharmacology. 62: 45-55. PMID 11150922 DOI: 10.1159/000056071  1
2000 Donkor IO, Zheng X, Miller DD. Synthesis and calpain inhibitory activity of alpha-ketoamides with 2,3-methanoleucine stereoisomers at the P2 position. Bioorganic & Medicinal Chemistry Letters. 10: 2497-500. PMID 11086714  1
2000 Mehta RC, Salazar-Bookaman MM, Fertel RH, De Los Angeles J, Nikulin VI, Fraundorfer PF, Miller DD, Feller DR. Biochemical and functional characterization of 1-benzyl substituted trimetoquinol affinity analogs on rat and human beta-adrenoceptors. Biochemical Pharmacology. 59: 517-29. PMID 10660118 DOI: 10.1016/S0006-2952(99)00376-7  1
1999 Jing L, Jagadeesh JM, De Los Angeles J, Miller DD, Patil PN. Depolarization of membrane potential and the smooth muscle contraction by isothiocyanatobenzyl imidazoline in guinea-pig stomach circular muscle. Naunyn-Schmiedeberg's Archives of Pharmacology. 360: 337-43. PMID 10543437  1
1999 Konkar AA, Vansal SS, Shams G, Fraundorfer PF, Zheng WP, Nikulin VI, De Los Angeles J, Fertel RH, Miller DD, Feller DR. Beta-adrenoceptor subtype activities of trimetoquinol derivatives: biochemical studies on human beta-adrenoceptors expressed in chinese hamster ovary cells. The Journal of Pharmacology and Experimental Therapeutics. 291: 875-83. PMID 10525112  1
1998 Lei L, Vaghy PL, Slavica M, De Los Angeles J, Smith B, Miller DD, Feller DR. Activation of L-type calcium channel by tolazoline derivatives: role of isothiocyanate moiety. Journal of Cardiovascular Pharmacology. 31: 721-33. PMID 9593072 DOI: 10.1097/00005344-199805000-00011  1
1997 Hill RA, Wallace LJ, Miller DD, Weinstein DM, Shams G, Tai H, Layer RT, Willins D, Uretsky NJ, Danthi SN. Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines. Journal of Medicinal Chemistry. 40: 3182-91. PMID 9379437 DOI: 10.1021/jm950028z  1
1997 Christoff JJ, Bradley L, Miller DD, Lei L, Rodriguez F, Fraundorfer P, Romstedt K, Shams G, Feller DR. Synthesis and evaluation of trimetoquinol derivatives: novel thromboxane A2/prostaglandin H2 antagonists with diminished beta-adrenergic agonist activity. Journal of Medicinal Chemistry. 40: 85-91. PMID 9016331 DOI: 10.1021/jm950896w  1
1997 Shams G, Romstedt KJ, Lust LA, Clark MT, Miller DD, Feller DR. Beta-adrenergic receptor and platelet inhibitory activities of a new series of trimetoquinol and related benzazepine analogs. General Pharmacology. 28: 323-30. PMID 9013212 DOI: 10.1016/S0306-3623(96)00223-6  1
1996 Ishikawa H, Miller DD, Patil PN. Irreversible agonist and antagonist properties of isothiocyanatobenzyl imidazoline in albino rabbit iris muscles Naunyn-Schmiedeberg's Archives of Pharmacology. 354: 362-368. PMID 8878068  1
1996 Konkar AA, Fraundorfer PF, Fertel RH, Burkman AM, Miller DD, Feller DR. Pharmacological activities of trimetoquinol and 1-benzyl halogen-substituted analogues on rat beta-adrenoceptor subtypes. European Journal of Pharmacology. 305: 63-71. PMID 8813533 DOI: 10.1016/0014-2999(96)00034-9  1
1996 Zhang X, Yao XT, Dalton JT, Shams G, Lei L, Patil PN, Feller DR, Hsu FL, George C, Miller DD. Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine. Journal of Medicinal Chemistry. 39: 3001-13. PMID 8709134 DOI: 10.1021/jm9506074  1
1994 Slavica M, Lei L, Patil PN, Kerezy A, Feller DR, Miller DD. Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta. Journal of Medicinal Chemistry. 37: 1874-81. PMID 8021927  1
1994 Fraundorfer PF, Fertel RH, Miller DD, Feller DR. Biochemical and pharmacological characterization of high-affinity trimetoquinol analogs on guinea pig and human beta adrenergic receptor subtypes: evidence for partial agonism. The Journal of Pharmacology and Experimental Therapeutics. 270: 665-74. PMID 7915318  1
1994 Hong SS, Romstedt KJ, Feller DR, Hsu FL, Cupps TL, Lyon RA, Miller DD. A structure-activity relationship study of benzylic modifications of 4-[1-(1-naphthyl)ethyl]-1H-imidazoles on alpha 1- and alpha 2-adrenergic receptors. Journal of Medicinal Chemistry. 37: 2328-33. PMID 7914537  1
1994 Fraundorfer PF, Lezama EJ, Salazar-Bookaman MM, Fertel RH, Miller DD, Feller DR. Isomeric-activity ratios of trimetoquinol enantiomers on beta-adrenergic receptor subtypes: functional and biochemical studies. Chirality. 6: 76-85. PMID 7911313 DOI: 10.1002/chir.530060207  1
1994 Farooqui T, Brooks K, Harrold MW, Miller DD, Wallace LJ, Uretsky NJ. Interaction of permanently charged metoclopramide analogs with D-2 dopamine receptors. General Pharmacology. 25: 1577-84. PMID 7721031 DOI: 10.1016/0306-3623(94)90357-3  1
1993 Abdel-Ghany YS, Ihnat MA, Miller DD, Kunin CM, Tong HH. Structure-activity relationship of glycine betaine analogs on osmotolerance of enteric bacteria. Journal of Medicinal Chemistry. 36: 784-9. PMID 8459406  1
1993 Kunin CM, Tong HH, Miller DD, Abdel-Ghany Y, Poggi MC, LeRudulier D. Effect of novel compound, 1-methyl-1-piperidino methane sulfonate (MPMS), on the osmoprotectant activity of glycine betaine, choline and L-proline in Escherichia coli. Archives of Microbiology. 160: 81-6. PMID 8397499 DOI: 10.1007/BF00288707  1
1993 Romstedt KJ, Shin Y, Shams G, Doyle K, Tantishaiyakul V, Clark MT, Adejare A, Hamada A, Miller DD, Feller DR. Halogen-substituted trimetoquinol analogs as thromboxane A2 receptor antagonists in platelets and aorta. Biochemical Pharmacology. 46: 2051-9. PMID 8267653 DOI: 10.1016/0006-2952(93)90647-F  1
1993 Shin Y, Romstedt KJ, Miller DD, Feller DR. Interactions of nonprostanoid trimetoquinol analogs with thromboxane A2/prostaglandin H2 receptors in human platelets, rat vascular endothelial cells and rat vascular smooth muscle cells. The Journal of Pharmacology and Experimental Therapeutics. 267: 1017-23. PMID 7903383  1
1992 Smar MW, Ares JJ, Nakayama T, Itabe H, Kador PF, Miller DD. Selective irreversible inhibitors of aldose reductase. Journal of Medicinal Chemistry. 35: 1117-20. PMID 1552504  0.01
1992 Willins DL, Wallace LJ, Miller DD, Uretsky NJ. alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonists in the nucleus accumbens and ventral pallidum decrease the hypermotility response to psychostimulant drugs. The Journal of Pharmacology and Experimental Therapeutics. 260: 1145-51. PMID 1372049  1
1992 Hong SS, Romstedt KJ, Feller DR, Hsu FL, George C, Cupps TL, Lyon RA, Miller DD. Resolution and adrenergic activities of the optical isomers of 4-[1-(1-naphthyl)ethyl]-1H-imidazole. Chirality. 4: 432-8. PMID 1361151 DOI: 10.1002/chir.530040706  1
1992 Amemiya Y, Hong SS, Venkataraman BV, Patil PN, Shams G, Romstedt K, Feller DR, Hsu FL, Miller DD. Synthesis and alpha-adrenergic activities of 2- and 4-substituted imidazoline and imidazole analogues. Journal of Medicinal Chemistry. 35: 750-5. PMID 1347319  1
1992 Markovich KM, Tantishaiyakul V, Hamada A, Miller DD, Romstedt KJ, Shams G, Shin Y, Fraundorfer PF, Doyle K, Feller DR. Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities. Journal of Medicinal Chemistry. 35: 466-79. PMID 1346651  1
1991 Shin Y, Romstedt KJ, Doyle K, Harrold MW, Gerhardt MA, Miller DD, Patil PN, Feller DR. Pharmacologic antagonism of thromboxane A2 receptors by trimetoquinol analogs in vitro and in vivo Chirality. 3: 112-117. PMID 1830752 DOI: 10.1002/chir.530030206  1
1991 Shams G, Fedyna J, Romstedt KJ, Adejare A, Miller DD, Roche VF, Feller DR. Pharmacological properties of novel bicyclic isoquinoline analogs in isolated guinea pig atria, trachea and in human platelets: Relationship to trimetoquinol General Pharmacology. 22: 1155-1163. PMID 1687397 DOI: 10.1016/0306-3623(91)90595-W  1
1991 Shams G, Venkataraman BV, Hamada A, Miller DD, Patil PN, Feller DR. Diversity of the pharmacological actions of some tolazoline analogues in human platelets and rat aorta. European Journal of Pharmacology. 199: 315-23. PMID 1655482 DOI: 10.1016/0014-2999(91)90495-C  1
1990 Ahn Ch, Shams G, Schotzinger RL, Miller DD, Feller DR. Stereostructure Activity Relationships of Catecholamines on Human Platelet Function Proceedings of the Society For Experimental Biology and Medicine. 194: 149-156. PMID 2190233 DOI: 10.3181/00379727-194-43071  1
1990 Miller DD, Hamada A, Clark MT, Adejare A, Patil PN, Shams G, Romstedt KJ, Kim SU, Intrasuksri U, McKenzie JL. Synthesis and alpha 2-adrenoceptor effects of substituted catecholimidazoline and catecholimidazole analogues in human platelets. Journal of Medicinal Chemistry. 33: 1138-44. PMID 2157007  1
1990 Shams G, Wallace LJ, Miller DD, Feller DR. Effects of thromboxane a2 on thoracic aorta of young and old rats: Use of selective thromboxane receptor antagonists Pharmacology. 40: 27-32. PMID 2139513 DOI: 10.1159/000138635  1
1990 Shams G, Harrold MW, Grazyl B, Miller DD, Feller DR. Pharmacological evaluation of the β-adrenoceptor agonist properties of N-benzyl substituted trimetoquinol analogues European Journal of Pharmacology. 184: 251-256. PMID 1981872 DOI: 10.1016/0014-2999(90)90616-E  1
1990 Shams G, Romstedt KJ, Gerhardt MA, Harrold MW, Miller DD, Feller DR. Pharmacological evaluation of the β-adrenoceptor agonist and thromboxane receptor blocking properties of 1-benzyl substituted trimetoquinol analogues European Journal of Pharmacology. 184: 21-31. PMID 1976530 DOI: 10.1016/0014-2999(90)90663-Q  1
1990 Nejman GD, Griffith R, Van Ligten P, Hoekstra J, Casto L, Miller DD, Brown CG. Hemodynamic effects of 1-[3,4-dihydroxyphenyl]-1,2-diaminoethane versus norepinephrine during ventricular fibrillation and cardiopulmonary resuscitation. Resuscitation. 20: 243-52. PMID 1965347  0.01
1989 Farooqui T, Wallace RA, Miller DD, Uretsky NJ. Effect of the inhibition of dopamine uptake on the dopamine- and dimethyldopamine-induced-inhibition of the potassium-evoked release of [3H]acetylcholine from striatal slices. General Pharmacology. 20: 731-6. PMID 2591702  0.04
1989 Venkataraman BV, Hamada A, Shams G, Miller DD, Feller DR, Patil PN. Paradoxical effects of isothiocyanate analog of tolazoline on rat aorta and human platelets Blood Vessels. 26: 335-346. PMID 2577124  1
1989 Nichols AJ, Hamada A, Adejare A, Miller DD, Patil PN, Ruffolo RR. Effect of aromatic fluorine substitution on the alpha and beta adrenoceptor-mediated effects of 3,4-dihydroxytolazoline in the pithed rat. The Journal of Pharmacology and Experimental Therapeutics. 248: 671-6. PMID 2537407  1
1989 Harrold MW, Wallace RA, Farooqui T, Wallace LJ, Uretsky N, Miller DD. Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogues of sulpiride Journal of Medicinal Chemistry. 32: 874-880. PMID 2522993  1
1988 Harrold MW, Grajzl B, Shin Y, Romstedt KJ, Feller DR, Miller DD. Synthesis and thromboxane A2 antagonist activity of N-benzyltrimetoquinol analogues Journal of Medicinal Chemistry. 31: 1506-1512. PMID 3397988  1
1988 Chang-Ho A, Romstedt KJ, Wallace LJ, Miller DD, Feller DR. Characterization of the inhibition of U46619-mediated human platelet activation by the trimetoquinol isomers. Evidence for endoperoxide/thromboxane A2 receptor blockade Biochemical Pharmacology. 37: 3023-3033. PMID 3134894 DOI: 10.1016/0006-2952(88)90292-4  1
1988 Ahn CH, Wallace LJ, Miller DD, Feller DR. Use of [3h]trimetoquinol as a radioligand in human platelets: Interaction with putative endoperoxide/thromboxane A2 receptor sites Thrombosis Research. 50: 387-399. PMID 2969151 DOI: 10.1016/0049-3848(88)90268-X  1
1988 Lamba-Kanwal VK, Hamada A, Adejare A, Clark MT, Miller DD, Patil PN. Activation of alpha-1 adrenoreceptors of rat aorta by analogs of imidazoline. The Journal of Pharmacology and Experimental Therapeutics. 245: 793-7. PMID 2838604  1
1987 Harrold MW, Gerhardt MA, Romstedt K, Feller DR, Miller DD. Synthesis and platelet antiaggregatory activity of trimetoquinol analogs as endoperoxide/thromboxane A2 antagonists Drug Design and Delivery. 1: 193-207. PMID 3509333  1
1987 Fedyna JS, Adejare A, Miller DD, Feller DR. Pharmacological evaluation of the β-adrenoceptor agonist and thromboxane antagonist properties of N-substituted trimetoquinol analogues European Journal of Pharmacology. 135: 161-171. PMID 2884118 DOI: 10.1016/0014-2999(87)90608-X  1
1987 Clark MT, Adejare A, Shams G, Feller DR, Miller DD. 5-fluoro- and 8-fluorotrimetoquinol: selective beta 2-adrenoceptor agonists. Journal of Medicinal Chemistry. 30: 86-90. PMID 2879920  1
1986 Adejare A, Miller DD, Fedyna JS, Ahn CH, Feller DR. Syntheses and β-adrenergic agonist and antiaggregatory properties of N-substituted trimetoquinol analogues Journal of Medicinal Chemistry. 29: 1603-1609. PMID 2875182  1
1981 Fuder H, Nelson WL, Miller DD, Patil PN. Alpha adrenoreceptors of rabbit aorta and stomach fundus Journal of Pharmacology and Experimental Therapeutics. 217: 1-9. PMID 6110772  1
1970 Nelson WL, Miller DD. Tricyclic norephedrine analogs. The isomeric 9-hydroxy-10-amino-1,2,3,4,4a,9,10,10a-(trans-4a,10a)-octahydrophenanthrenes Journal of Medicinal Chemistry. 13: 807-814. PMID 4394055  1
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