Christopher Hunter - Publications

Affiliations: 
Pathobiology University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, United States 

202 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, ... ... Hunter CA, et al. Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses. Mucosal Immunology. PMID 38508522 DOI: 10.1016/j.mucimm.2024.03.003  0.856
2024 Aldridge DL, Moodley D, Park J, Phan AT, Rausch M, White KF, Ren Y, Golin K, Radaelli E, Kedl R, Holland PM, Hill J, Hunter CA. Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells. Mbio. e0008324. PMID 38376210 DOI: 10.1128/mbio.00083-24  0.498
2023 Pardy RD, Walzer KA, Wallbank BA, Byerly JH, O'Dea KM, Cohn IS, Haskins BE, Roncaioli JL, Smith EJ, Buenconsejo GY, Striepen B, Hunter CA. Analysis of intestinal epithelial cell responses to highlights the temporal effects of IFN-γ on parasite restriction. Biorxiv : the Preprint Server For Biology. PMID 38014210 DOI: 10.1101/2023.11.14.567008  0.823
2023 Cohn IS, Wallbank BA, Haskins BE, O'Dea KM, Pardy RD, Shaw S, Merolle MI, Gullicksrud JA, Christian DA, Striepen B, Hunter CA. Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4 T cell-mediated resistance to . Biorxiv : the Preprint Server For Biology. PMID 38014026 DOI: 10.1101/2023.11.11.566669  0.858
2023 Lee R, Yoon BI, Hunter CA, Kwon HM, Sung HW, Park J. Short chain fatty acids facilitate protective immunity by macrophages and T cells during acute fowl adenovirus-4 infection. Scientific Reports. 13: 17999. PMID 37865711 DOI: 10.1038/s41598-023-45340-8  0.369
2023 Pardy RD, Wallbank BA, Striepen B, Hunter CA. Immunity to Cryptosporidium: insights into principles of enteric responses to infection. Nature Reviews. Immunology. PMID 37697084 DOI: 10.1038/s41577-023-00932-3  0.824
2023 Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, ... ... Hunter CA, et al. Dendritic cell-mediated responses to secreted effectors are required for parasite-specific CD8 T cell responses. Biorxiv : the Preprint Server For Biology. PMID 37645924 DOI: 10.1101/2023.08.16.553566  0.853
2023 Ivanova DL, Thompson SB, Klarquist J, Harbell MG, Kilgore AM, Lasda EL, Hesselberth JR, Hunter CA, Kedl RM. Vaccine adjuvant-elicited CD8 T cell immunity is co-dependent on T-bet and FOXO1. Cell Reports. 42: 112911. PMID 37516968 DOI: 10.1016/j.celrep.2023.112911  0.366
2023 Pereira JA, Lanzar Z, Clark JT, Hart AP, Douglas BB, Shallberg L, O'Dea K, Christian DA, Hunter CA. PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis. Frontiers in Immunology. 14: 997376. PMID 36960049 DOI: 10.3389/fimmu.2023.997376  0.749
2023 Clark JT, Weizman OE, Aldridge DL, Shallberg LA, Eberhard J, Lanzar Z, Wasche D, Huck JD, Zhou T, Ring AM, Hunter CA. IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii. Cell Reports. 42: 112147. PMID 36827187 DOI: 10.1016/j.celrep.2023.112147  0.652
2022 Cohn IS, Henrickson SE, Striepen B, Hunter CA. Immunity to Cryptosporidium: Lessons from Acquired and Primary Immunodeficiencies. Journal of Immunology (Baltimore, Md. : 1950). 209: 2261-2268. PMID 36469846 DOI: 10.4049/jimmunol.2200512  0.389
2022 Schneider CA, Figueroa Velez DX, Orchanian SB, Shallberg LA, Agalliu D, Hunter CA, Gandhi SP, Lodoen MB. Toxoplasma gondii Dissemination in the Brain Is Facilitated by Infiltrating Peripheral Immune Cells. Mbio. e0283822. PMID 36445695 DOI: 10.1128/mbio.02838-22  0.415
2022 Pritchard GH, Phan AT, Christian DA, Blain TJ, Fang Q, Johnson J, Roy NH, Shallberg L, Kedl RM, Hunter CA. Early T-bet promotes LFA1 upregulation required for CD8+ effector and memory T cell development. The Journal of Experimental Medicine. 220. PMID 36445307 DOI: 10.1084/jem.20191287  0.839
2022 Shallberg LA, Hunter CA. T cell surveillance of Toxoplasma gondii: Basic insights into how T cells operate in the central nervous system. Current Opinion in Neurobiology. 77: 102640. PMID 36240583 DOI: 10.1016/j.conb.2022.102640  0.394
2022 Christian DA, Adams TA, Shallberg LA, Phan AT, Smith TE, Abraha M, Perry J, Ruthel G, Clark JT, Pritchard GH, Aronson LR, Gossa S, McGavern DB, Kedl RM, Hunter CA. cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory. Science Immunology. 7: eabq7432. PMID 36179012 DOI: 10.1126/sciimmunol.abq7432  0.854
2022 Shallberg LA, Phan AT, Christian DA, Perry JA, Haskins BE, Beiting DP, Harris TH, Koshy AA, Hunter CA. Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis. Plos Pathogens. 18: e1010296. PMID 35727849 DOI: 10.1371/journal.ppat.1010296  0.809
2022 Gibson AR, Sateriale A, Dumaine JE, Engiles JB, Pardy RD, Gullicksrud JA, O'Dea KM, Doench JG, Beiting DP, Hunter CA, Striepen B. A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition. Plos Pathogens. 18: e1010003. PMID 35584177 DOI: 10.1371/journal.ppat.1010003  0.825
2022 Doke T, Abedini A, Aldridge DL, Yang YW, Park J, Hernandez CM, Balzer MS, Shrestra R, Coppock G, Rico JMI, Han SY, Kim J, Xin S, Piliponsky AM, Angelozzi M, ... ... Hunter CA, et al. Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. Nature Immunology. PMID 35552540 DOI: 10.1038/s41590-022-01200-7  0.801
2022 Perry JA, Shallberg L, Clark JT, Gullicksrud JA, DeLong JH, Douglas BB, Hart AP, Lanzar Z, O'Dea K, Konradt C, Park J, Kuchroo JR, Grubaugh D, Zaretsky AG, Brodsky IE, ... ... Hunter CA, et al. PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection. Nature Immunology. PMID 35437326 DOI: 10.1038/s41590-022-01170-w  0.81
2021 Gullicksrud JA, Sateriale A, Engiles JB, Gibson AR, Shaw S, Hutchins ZA, Martin L, Christian DA, Taylor GA, Yamamoto M, Beiting DP, Striepen B, Hunter CA. Enterocyte-innate lymphoid cell crosstalk drives early IFN-γ-mediated control of Cryptosporidium. Mucosal Immunology. PMID 34750455 DOI: 10.1038/s41385-021-00468-6  0.848
2021 Frickel EM, Hunter CA. Lessons from Toxoplasma: Host responses that mediate parasite control and the microbial effectors that subvert them. The Journal of Experimental Medicine. 218. PMID 34670268 DOI: 10.1084/jem.20201314  0.317
2021 Lin CH, Chen MC, Lin LL, Christian DA, Min B, Hunter CA, Lu LF. Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes. The Journal of Experimental Medicine. 218. PMID 34554189 DOI: 10.1084/jem.20210021  0.766
2021 Klarquist J, Cross EW, Thompson SB, Willett B, Aldridge DL, Caffrey-Carr AK, Xu Z, Hunter CA, Getahun A, Kedl RM. B cells promote CD8 T cell primary and memory responses to subunit vaccines. Cell Reports. 36: 109591. PMID 34433030 DOI: 10.1016/j.celrep.2021.109591  0.458
2021 Shallberg LA, Hunter CA. Long live the king: Toxoplasma gondii nucleomodulin inhibits necroptotic cell death. Cell Host & Microbe. 29: 1165-1166. PMID 34265248 DOI: 10.1016/j.chom.2021.06.010  0.303
2021 Aldridge DL, Phan AT, de Waal Malefyt R, Hunter CA. Limited Impact of the Inhibitory Receptor TIGIT on NK and T Cell Responses during Infection. Immunohorizons. 5: 384-394. PMID 34088852 DOI: 10.4049/immunohorizons.2100007  0.587
2021 Clark JT, Christian DA, Gullicksrud JA, Perry JA, Park J, Jacquet M, Tarrant JC, Radaelli E, Silver J, Hunter CA. IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to . Elife. 10. PMID 33929319 DOI: 10.7554/eLife.65614  0.844
2021 Jones SA, Hunter CA. Is IL-6 a key cytokine target for therapy in COVID-19? Nature Reviews. Immunology. PMID 33850327 DOI: 10.1038/s41577-021-00553-8  0.38
2021 Sateriale A, Gullicksrud JA, Engiles JB, McLeod BI, Kugler EM, Henao-Mejia J, Zhou T, Ring AM, Brodsky IE, Hunter CA, Striepen B. The intestinal parasite is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33372132 DOI: 10.1073/pnas.2007807118  0.829
2020 Coppock GM, Aronson LR, Park J, Qiu C, Park J, DeLong JH, Radaelli E, Suszták K, Hunter CA. Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 32522836 DOI: 10.4049/Jimmunol.1901463  0.834
2020 Park J, Hunter CA. The role of macrophages in protective and pathological responses to Toxoplasma gondii. Parasite Immunology. e12712. PMID 32187690 DOI: 10.1111/Pim.12712  0.376
2020 Chen L, Christian DA, Kochanowsky JA, Phan AT, Clark JT, Wang S, Berry C, Oh J, Chen X, Roos DS, Beiting DP, Koshy AA, Hunter CA. The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses. The Journal of Experimental Medicine. 217. PMID 31961916 DOI: 10.1084/Jem.20181757  0.829
2019 Park J, DeLong JH, Knox J, Konradt C, Tait Wojno ED, Hunter CA. Impact of IL-27p28 on T and B cell responses during toxoplasmosis. Infection and Immunity. PMID 31548322 DOI: 10.1128/Iai.00455-19  0.82
2019 DeLong JH, O'Hara Hall A, Rausch M, Moodley D, Perry J, Park J, Phan AT, Beiting DP, Kedl RM, Hill JA, Hunter CA. IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors. Immunohorizons. 3: 13-25. PMID 31356173 DOI: 10.4049/immunohorizons.1800083  0.451
2019 Sateriale A, Šlapeta J, Baptista R, Engiles JB, Gullicksrud JA, Herbert GT, Brooks CF, Kugler EM, Kissinger JC, Hunter CA, Striepen B. A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity. Cell Host & Microbe. PMID 31231045 DOI: 10.1016/J.Chom.2019.05.006  0.788
2019 DeLaney AA, Berry CT, Christian DA, Hart A, Bjanes E, Wynosky-Dolfi MA, Li X, Tummers B, Udalova IA, Chen YH, Hershberg U, Freedman BD, Hunter CA, Brodsky IE. Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against . Proceedings of the National Academy of Sciences of the United States of America. PMID 31147458 DOI: 10.1073/Pnas.1820529116  0.673
2019 Wang S, El-Fahmawi A, Christian DA, Fang Q, Radaelli E, Chen L, Sullivan MC, Misic AM, Ellringer JA, Zhu XQ, Winter SE, Hunter CA, Beiting DP. Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production. Mbio. 10. PMID 31138751 DOI: 10.1128/Mbio.00935-19  0.782
2019 Tait Wojno ED, Hunter CA, Stumhofer JS. The Immunobiology of the Interleukin-12 Family: Room for Discovery. Immunity. 50: 851-870. PMID 30995503 DOI: 10.1016/J.Immuni.2019.03.011  0.713
2019 Pritchard GH, Kedl RM, Hunter CA. The evolving role of T-bet in resistance to infection. Nature Reviews. Immunology. PMID 30846856 DOI: 10.1038/S41577-019-0145-4  0.848
2019 Hunter C, Zhu J, Long EO. Decision letter: Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells Elife. DOI: 10.7554/Elife.47605.023  0.401
2018 Klarquist J, Chitrakar A, Pennock ND, Kilgore AM, Blain T, Zheng C, Danhorn T, Walton K, Jiang L, Sun J, Hunter CA, D'Alessandro A, Kedl RM. Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis. Science Immunology. 3. PMID 30194241 DOI: 10.1126/Sciimmunol.Aas9822  0.355
2018 Konradt C, Hunter CA. Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity. European Journal of Immunology. PMID 30160302 DOI: 10.1002/Eji.201646789  0.78
2018 DeLong JH, Hall AO, Konradt C, Coppock GM, Park J, Harms Pritchard G, Hunter CA. Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1. Journal of Immunology (Baltimore, Md. : 1950). PMID 29358280 DOI: 10.4049/Jimmunol.1701154  0.86
2017 Pritchard GH, Cross EW, Strobel M, Jameson SC, Kedl RM, Hogquist KA, Hunter CA. Corrigendum: Spontaneous partial loss of the OT-I transgene. Nature Immunology. 18: 951. PMID 28722721 DOI: 10.1038/Ni0817-951B  0.755
2017 O'Brien CA, Overall C, Konradt C, O'Hara Hall AC, Hayes NW, Wagage S, John B, Christian DA, Hunter CA, Harris TH. CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28389591 DOI: 10.4049/Jimmunol.1601581  0.845
2017 Glatman Zaretsky A, Konradt C, Dépis F, Wing JB, Goenka R, Atria DG, Silver JS, Cho S, Wolf AI, Quinn WJ, Engiles JB, Brown DC, Beiting D, Erikson J, Allman D, ... ... Hunter CA, et al. T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow. Cell Reports. 18: 1906-1916. PMID 28228257 DOI: 10.1016/J.Celrep.2017.01.067  0.831
2017 Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Christian DA, Harms Pritchard G, Fang Q, Buza EL, Jain D, Elloso MM, López CB, Hunter CA. IL-27 LIMITS TYPE 2 IMMUNOPATHOLOGY FOLLOWING PARAINFLUENZA VIRUS INFECTION. Plos Pathogens. 13: e1006173. PMID 28129374 DOI: 10.1371/Journal.Ppat.1006173  0.861
2016 Hidano S, Randall LM, Dawson L, Dietrich HK, Konradt C, Klover PJ, John B, Harris TH, Fang Q, Turek B, Kobayashi T, Hennighausen L, Beiting DP, Koshy AA, Hunter CA. STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System. Mbio. 7. PMID 27834206 DOI: 10.1128/Mbio.01881-16  0.806
2016 Konradt C, Ueno N, Christian DA, Delong JH, Pritchard GH, Herz J, Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA. Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system. Nature Microbiology. 1: 16001. PMID 27572166 DOI: 10.1038/Nmicrobiol.2016.1  0.805
2016 Ruella M, Barrett DM, Kenderian SS, Shestova O, Hofmann TJ, Perazzelli J, Klichinsky M, Aikawa V, Nazimuddin F, Kozlowski M, Scholler J, Lacey SF, Melenhorst JJ, Morrissette JJ, Christian DA, ... Hunter CA, et al. Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. The Journal of Clinical Investigation. PMID 27571406 DOI: 10.1172/Jci87366  0.636
2016 Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA, Scott P. Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 27474074 DOI: 10.4049/Jimmunol.1600717  0.785
2016 Silver JS, Kearley J, Copenhaver AM, Sanden C, Mori M, Yu L, Pritchard GH, Berlin AA, Hunter CA, Bowler R, Erjefalt JS, Kolbeck R, Humbles AA. Erratum: Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nature Immunology. 17: 1005. PMID 27434015 DOI: 10.1038/ni0816-1005c  0.779
2016 Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP. Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27430719 DOI: 10.4049/Jimmunol.1600522  0.78
2016 Silver JS, Kearley J, Copenhaver AM, Sanden C, Mori M, Yu L, Pritchard GH, Berlin AA, Hunter CA, Bowler R, Erjefalt JS, Kolbeck R, Humbles AA. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nature Immunology. PMID 27111143 DOI: 10.1038/Ni.3443  0.847
2016 Pritchard GH, Cross EW, Strobel M, Jameson SC, Kedl RM, Hogquist KA, Hunter CA. Spontaneous partial loss of the OT-I transgene. Nature Immunology. 17: 471. PMID 27092794 DOI: 10.1038/Ni.3411  0.751
2015 Villarino AV, O'Shea JJ, Hunter CA. IL-27 shakes up the establishment of ectopic lymphoid structures. The Journal of Experimental Medicine. 212: 1757. PMID 26482142 DOI: 10.1084/jem.21211insight4  0.678
2015 Dupont CD, Harms Pritchard G, Hidano S, Christian DA, Wagage S, Muallem G, Tait Wojno ED, Hunter CA. Flt3 Ligand Is Essential for Survival and Protective Immune Responses during Toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 26385522 DOI: 10.4049/Jimmunol.1500690  0.862
2015 Konradt C, Hunter CA. Immune-mediated viral clearance from the CNS without collateral damage. The Journal of Experimental Medicine. 212: 1141-2. PMID 26216603 DOI: 10.1084/Jem.2128Insight3  0.778
2015 Beiting DP, Hidano S, Baggs JE, Geskes JM, Fang Q, Wherry EJ, Hunter CA, Roos DS, Cherry S. The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii. Plos Biology. 13: e1002200. PMID 26196739 DOI: 10.1371/Journal.Pbio.1002200  0.796
2015 Wagage S, Harms Pritchard G, Dawson L, Buza EL, Sonnenberg GF, Hunter CA. The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection. Plos One. 10: e0128335. PMID 26010337 DOI: 10.1371/Journal.Pone.0128335  0.849
2015 Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, ... ... Hunter CA, et al. Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity. Immunity. 42: 877-89. PMID 25992861 DOI: 10.1016/J.Immuni.2015.04.014  0.715
2015 Hunter CA, Jones SA. IL-6 as a keystone cytokine in health and disease. Nature Immunology. 16: 448-57. PMID 25898198 DOI: 10.1038/Ni.3153  0.339
2015 Yoshida H, Hunter CA. The immunobiology of interleukin-27. Annual Review of Immunology. 33: 417-43. PMID 25861977 DOI: 10.1146/Annurev-Immunol-032414-112134  0.457
2015 Banigan EJ, Harris TH, Christian DA, Hunter CA, Liu AJ. Heterogeneous CD8+ T cell migration in the lymph node in the absence of inflammation revealed by quantitative migration analysis. Plos Computational Biology. 11: e1004058. PMID 25692801 DOI: 10.1371/Journal.Pcbi.1004058  0.786
2015 Lee HM, Fleige A, Forman R, Cho S, Khan AA, Lin LL, Nguyen DT, O'Hara-Hall A, Yin Z, Hunter CA, Muller W, Lu LF. IFNγ signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells. Plos Pathogens. 11: e1004635. PMID 25658840 DOI: 10.1371/Journal.Ppat.1004635  0.489
2015 Harms Pritchard G, Hall AO, Christian DA, Wagage S, Fang Q, Muallem G, John B, Glatman Zaretsky A, Dunn WG, Perrigoue J, Reiner SL, Hunter CA. Diverse roles for T-bet in the effector responses required for resistance to infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 1131-40. PMID 25556247 DOI: 10.4049/Jimmunol.1401617  0.85
2015 Agarwal P, Rashighi M, Essien KI, Richmond JM, Randall L, Pazoki-Toroudi H, Hunter CA, Harris JE. Simvastatin prevents and reverses depigmentation in a mouse model of vitiligo. The Journal of Investigative Dermatology. 135: 1080-8. PMID 25521459 DOI: 10.1038/Jid.2014.529  0.517
2014 Muallem G, Hunter CA. ParadYm shift: Ym1 and Ym2 as innate immunological regulators of IL-17. Nature Immunology. 15: 1099-100. PMID 25396344 DOI: 10.1038/Ni.3032  0.401
2014 Hunter C, Christian D. Parasite uses host NFAT to co-opt immune response. The Journal of Experimental Medicine. 211: 1923. PMID 25246389 DOI: 10.1084/Jem.21110Insight2  0.657
2014 Christian DA, Koshy AA, Reuter MA, Betts MR, Boothroyd JC, Hunter CA. Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis. Infection and Immunity. 82: 4056-67. PMID 25024368 DOI: 10.1128/Iai.01643-14  0.726
2014 Liu FD, Kenngott EE, Schröter MF, Kühl A, Jennrich S, Watzlawick R, Hoffmann U, Wolff T, Norley S, Scheffold A, Stumhofer JS, Saris CJ, Schwab JM, Hunter CA, Debes GF, et al. Timed action of IL-27 protects from immunopathology while preserving defense in influenza. Plos Pathogens. 10: e1004110. PMID 24809349 DOI: 10.1371/Journal.Ppat.1004110  0.727
2014 Dupont CD, Christian DA, Selleck EM, Pepper M, Leney-Greene M, Harms Pritchard G, Koshy AA, Wagage S, Reuter MA, Sibley LD, Betts MR, Hunter CA. Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii. Plos Pathogens. 10: e1004047. PMID 24722202 DOI: 10.1371/Journal.Ppat.1004047  0.854
2014 Rashighi M, Agarwal P, Richmond JM, Harris TH, Dresser K, Su MW, Zhou Y, Deng A, Hunter CA, Luster AD, Harris JE. CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo. Science Translational Medicine. 6: 223ra23. PMID 24523323 DOI: 10.1126/Scitranslmed.3007811  0.732
2014 Beiting DP, Peixoto L, Akopyants NS, Beverley SM, Wherry EJ, Christian DA, Hunter CA, Brodsky IE, Roos DS. Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. Plos One. 9: e88398. PMID 24505488 DOI: 10.1371/Journal.Pone.0088398  0.735
2014 Leung JM, Rould MA, Konradt C, Hunter CA, Ward GE. Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay. Plos One. 9: e85763. PMID 24489670 DOI: 10.1371/Journal.Pone.0085763  0.775
2014 Wagage S, John B, Krock BL, Hall AO, Randall LM, Karp CL, Simon MC, Hunter CA. The aryl hydrocarbon receptor promotes IL-10 production by NK cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 1661-70. PMID 24403534 DOI: 10.4049/Jimmunol.1300497  0.845
2014 Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE. Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell. 14: 81-93. PMID 24268694 DOI: 10.1016/J.Stem.2013.10.009  0.673
2013 Iqbal J, Sun L, Cao J, Yuen T, Lu P, Bab I, Leu NA, Srinivasan S, Wagage S, Hunter CA, Nebert DW, Zaidi M, Avadhani NG. Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. Proceedings of the National Academy of Sciences of the United States of America. 110: 11115-20. PMID 23776235 DOI: 10.1073/Pnas.1220919110  0.756
2013 Stumhofer JS, Silver JS, Hunter CA. IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection. Plos One. 8: e62889. PMID 23667536 DOI: 10.1371/Journal.Pone.0062889  0.852
2013 Villegas-Mendez A, de Souza JB, Lavelle SW, Gwyer Findlay E, Shaw TN, van Rooijen N, Saris CJ, Hunter CA, Riley EM, Couper KN. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. Plos Pathogens. 9: e1003293. PMID 23593003 DOI: 10.1371/Journal.Ppat.1003293  0.482
2013 Jensen KD, Hu K, Whitmarsh RJ, Hassan MA, Julien L, Lu D, Chen L, Hunter CA, Saeij JP. Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15. Infection and Immunity. 81: 2156-67. PMID 23545295 DOI: 10.1128/Iai.01185-12  0.331
2013 Gwyer Findlay E, Villegas-Mendez A, de Souza JB, Inkson CA, Shaw TN, Saris CJ, Hunter CA, Riley EM, Couper KN. IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection. Journal of Immunology (Baltimore, Md. : 1950). 190: 4553-61. PMID 23536628 DOI: 10.4049/Jimmunol.1202916  0.538
2013 Gregg B, Taylor BC, John B, Tait-Wojno ED, Girgis NM, Miller N, Wagage S, Roos DS, Hunter CA. Replication and distribution of Toxoplasma gondii in the small intestine after oral infection with tissue cysts. Infection and Immunity. 81: 1635-43. PMID 23460516 DOI: 10.1128/Iai.01126-12  0.81
2012 Hunter CA, Kastelein R. Interleukin-27: balancing protective and pathological immunity. Immunity. 37: 960-9. PMID 23244718 DOI: 10.1016/J.Immuni.2012.11.003  0.366
2012 Hunter CA, Sibley LD. Modulation of innate immunity by Toxoplasma gondii virulence effectors. Nature Reviews. Microbiology. 10: 766-78. PMID 23070557 DOI: 10.1038/Nrmicro2858  0.327
2012 Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, Harris TH, Grainger J, Wojno ED, Wagage S, Roos DS, ... ... Hunter CA, et al. The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 37: 511-23. PMID 22981537 DOI: 10.1016/j.immuni.2012.06.014  0.851
2012 Dupont CD, Christian DA, Hunter CA. Immune response and immunopathology during toxoplasmosis. Seminars in Immunopathology. 34: 793-813. PMID 22955326 DOI: 10.1007/S00281-012-0339-3  0.682
2012 Wiehagen KR, Corbo-Rodgers E, Li S, Staub ES, Hunter CA, Morrisey EE, Maltzman JS. Foxp4 is dispensable for T cell development, but required for robust recall responses. Plos One. 7: e42273. PMID 22912696 DOI: 10.1371/Journal.Pone.0042273  0.439
2012 Koshy AA, Dietrich HK, Christian DA, Melehani JH, Shastri AJ, Hunter CA, Boothroyd JC. Toxoplasma co-opts host cells it does not invade. Plos Pathogens. 8: e1002825. PMID 22910631 DOI: 10.1371/Journal.Ppat.1002825  0.667
2012 Glatman Zaretsky A, Silver JS, Siwicki M, Durham A, Ware CF, Hunter CA. Infection with Toxoplasma gondii alters lymphotoxin expression associated with changes in splenic architecture. Infection and Immunity. 80: 3602-10. PMID 22851754 DOI: 10.1128/Iai.00333-12  0.684
2012 Young A, Linehan E, Hams E, O'Hara Hall AC, McClurg A, Johnston JA, Hunter CA, Fallon PG, Fitzgerald DC. Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27. Journal of Immunology (Baltimore, Md. : 1950). 189: 2079-83. PMID 22837488 DOI: 10.4049/Jimmunol.1200131  0.462
2012 Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, ... Hunter CA, et al. Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1. Immunity. 36: 1017-30. PMID 22726954 DOI: 10.1016/J.Immuni.2012.03.024  0.461
2012 Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, Hafalla JC, Blount DG, Hunter CA, Riley EM, Couper KN. IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. Journal of Immunology (Baltimore, Md. : 1950). 189: 968-79. PMID 22723523 DOI: 10.4049/Jimmunol.1200688  0.772
2012 Harris TH, Banigan EJ, Christian DA, Konradt C, Tait Wojno ED, Norose K, Wilson EH, John B, Weninger W, Luster AD, Liu AJ, Hunter CA. Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. Nature. 486: 545-8. PMID 22722867 DOI: 10.1038/Nature11098  0.838
2012 Hall AO, Silver JS, Hunter CA. The immunobiology of IL-27. Advances in Immunology. 115: 1-44. PMID 22608254 DOI: 10.1016/B978-0-12-394299-9.00001-1  0.699
2012 Christian DA, Hunter CA. Particle-mediated delivery of cytokines for immunotherapy. Immunotherapy. 4: 425-41. PMID 22512636 DOI: 10.2217/Imt.12.26  0.659
2012 Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, Fairweather D, Satoskar AR, Garcia KC, Hunter CA, Drake CG, Murray PJ, Vignali DA. The composition and signaling of the IL-35 receptor are unconventional. Nature Immunology. 13: 290-9. PMID 22306691 DOI: 10.1038/Ni.2227  0.384
2012 Harris JE, Harris TH, Weninger W, Wherry EJ, Hunter CA, Turka LA. A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin. The Journal of Investigative Dermatology. 132: 1869-76. PMID 22297636 DOI: 10.1038/Jid.2011.463  0.81
2012 Wojno ED, Hunter CA. New directions in the basic and translational biology of interleukin-27. Trends in Immunology. 33: 91-7. PMID 22177689 DOI: 10.1016/J.It.2011.11.003  0.412
2011 Sansing LH, Harris TH, Welsh FA, Kasner SE, Hunter CA, Kariko K. Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage. Annals of Neurology. 70: 646-56. PMID 22028224 DOI: 10.1002/Ana.22528  0.707
2011 John B, Ricart B, Tait Wojno ED, Harris TH, Randall LM, Christian DA, Gregg B, De Almeida DM, Weninger W, Hammer DA, Hunter CA. Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis. Plos Pathogens. 7: e1002246. PMID 21949652 DOI: 10.1371/Journal.Ppat.1002246  0.823
2011 Whitmarsh RJ, Gray CM, Gregg B, Christian DA, May MJ, Murray PJ, Hunter CA. A critical role for SOCS3 in innate resistance to Toxoplasma gondii. Cell Host & Microbe. 10: 224-36. PMID 21925110 DOI: 10.1016/J.Chom.2011.07.009  0.743
2011 Barkhuff WD, Gilk SD, Whitmarsh R, Tilley LD, Hunter C, Ward GE. Targeted disruption of TgPhIL1 in Toxoplasma gondii results in altered parasite morphology and fitness. Plos One. 6: e23977. PMID 21901148 DOI: 10.1371/Journal.Pone.0023977  0.381
2011 Gregg B, Dzierszinski F, Tait E, Jordan KA, Hunter CA, Roos DS. Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii. Plos One. 6: e22936. PMID 21829561 DOI: 10.1371/Journal.Pone.0022936  0.421
2011 Sansing LH, Harris TH, Kasner SE, Hunter CA, Kariko K. Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage. Acta Neurochirurgica. Supplement. 111: 173-8. PMID 21725751 DOI: 10.1007/978-3-7091-0693-8_29  0.72
2011 Goenka R, Barnett LG, Silver JS, O'Neill PJ, Hunter CA, Cancro MP, Laufer TM. Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 1091-5. PMID 21715693 DOI: 10.4049/Jimmunol.1100853  0.793
2011 Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA. A role for IL-27 in limiting T regulatory cell populations. Journal of Immunology (Baltimore, Md. : 1950). 187: 266-73. PMID 21622862 DOI: 10.4049/Jimmunol.1004182  0.84
2011 Silver JS, Stumhofer JS, Passos S, Ernst M, Hunter CA. IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 187: 350-60. PMID 21606248 DOI: 10.4049/Jimmunol.1004144  0.829
2011 Aronson LR, Stumhofer JS, Drobatz KJ, Hunter CA. Effect of cyclosporine, dexamethasone, and human CTLA4-Ig on production of cytokines in lymphocytes of clinically normal cats and cats undergoing renal transplantation. American Journal of Veterinary Research. 72: 541-9. PMID 21453156 DOI: 10.2460/Ajvr.72.4.541  0.643
2011 Ricart BG, John B, Lee D, Hunter CA, Hammer DA. Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4. Journal of Immunology (Baltimore, Md. : 1950). 186: 53-61. PMID 21106854 DOI: 10.4049/Jimmunol.1002358  0.745
2011 Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 409-19. PMID 20826539 DOI: 10.1096/Fj.10-166843  0.793
2011 Norose K, Kikumura A, Luster AD, Hunter CA, Harris TH. CXCL10 is required to maintain T-cell populations and to control parasite replication during chronic ocular toxoplasmosis. Investigative Ophthalmology & Visual Science. 52: 389-98. PMID 20811054 DOI: 10.1167/Iovs.10-5819  0.696
2010 Jordan KA, Dupont CD, Tait ED, Liou HC, Hunter CA. Role of the NF-κB transcription factor c-Rel in the generation of CD8+ T-cell responses to Toxoplasma gondii. International Immunology. 22: 851-61. PMID 21118906 DOI: 10.1093/Intimm/Dxq439  0.45
2010 Stumhofer JS, Tait ED, Quinn WJ, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, ... ... Hunter CA, et al. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nature Immunology. 11: 1119-26. PMID 21057510 DOI: 10.1038/Ni.1957  0.813
2010 Ramón HE, Cejas PJ, LaRosa D, Rahman A, Harris JE, Zhang J, Hunter C, Choi Y, Turka LA. EGR-2 is not required for in vivo CD4 T cell mediated immune responses. Plos One. 5: e12904. PMID 20886122 DOI: 10.1371/Journal.Pone.0012904  0.77
2010 John B, Weninger W, Hunter CA. Advances in imaging the innate and adaptive immune response to Toxoplasma gondii. Future Microbiology. 5: 1321-8. PMID 20860479 DOI: 10.2217/Fmb.10.97  0.742
2010 Findlay EG, Greig R, Stumhofer JS, Hafalla JC, de Souza JB, Saris CJ, Hunter CA, Riley EM, Couper KN. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 2482-92. PMID 20631310 DOI: 10.4049/Jimmunol.0904019  0.798
2010 Tait ED, Jordan KA, Dupont CD, Harris TH, Gregg B, Wilson EH, Pepper M, Dzierszinski F, Roos DS, Hunter CA. Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 1502-12. PMID 20592284 DOI: 10.4049/Jimmunol.0903450  0.867
2010 Jordan KA, Hunter CA. Regulation of CD8+ T cell responses to infection with parasitic protozoa. Experimental Parasitology. 126: 318-25. PMID 20493842 DOI: 10.1016/J.Exppara.2010.05.008  0.445
2010 Wilson EH, Weninger W, Hunter CA. Trafficking of immune cells in the central nervous system. The Journal of Clinical Investigation. 120: 1368-79. PMID 20440079 DOI: 10.1172/Jci41911  0.57
2010 Harris TH, Wilson EH, Tait ED, Buckley M, Shapira S, Caamano J, Artis D, Hunter CA. NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS. Journal of Neuroimmunology. 222: 19-28. PMID 20156658 DOI: 10.1016/J.Jneuroim.2009.12.009  0.842
2010 Passos ST, Silver JS, O'Hara AC, Sehy D, Stumhofer JS, Hunter CA. IL-6 promotes NK cell production of IL-17 during toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 1776-83. PMID 20083665 DOI: 10.4049/Jimmunol.0901843  0.839
2009 Oldenhove G, Bouladoux N, Wohlfert EA, Hall JA, Chou D, Dos Santos L, O'Brien S, Blank R, Lamb E, Natarajan S, Kastenmayer R, Hunter C, Grigg ME, Belkaid Y. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity. 31: 772-86. PMID 19896394 DOI: 10.1016/J.Immuni.2009.10.001  0.574
2009 Middleton MK, Zukas AM, Rubinstein T, Kinder M, Wilson EH, Zhu P, Blair IA, Hunter CA, Puré E. 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis. Infection and Immunity. 77: 5690-700. PMID 19822654 DOI: 10.1128/Iai.00560-09  0.665
2009 Anderson CF, Stumhofer JS, Hunter CA, Sacks D. IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 4619-27. PMID 19748991 DOI: 10.4049/Jimmunol.0804024  0.781
2009 Troy AE, Zaph C, Du Y, Taylor BC, Guild KJ, Hunter CA, Saris CJM, Artis D. IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis Journal of Immunology. 183: 2037-2044. PMID 19596985 DOI: 10.4049/Jimmunol.0802918  0.675
2009 John B, Harris TH, Tait ED, Wilson EH, Gregg B, Ng LG, Mrass P, Roos DS, Dzierszinski F, Weninger W, Hunter CA. Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. Plos Pathogens. 5: e1000505. PMID 19578440 DOI: 10.1371/Journal.Ppat.1000505  0.842
2009 Jordan KA, Wilson EH, Tait ED, Fox BA, Roos DS, Bzik DJ, Dzierszinski F, Hunter CA. Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infection and Immunity. 77: 3894-901. PMID 19528214 DOI: 10.1128/Iai.00024-09  0.672
2009 Tait ED, Hunter CA. Advances in understanding immunity to Toxoplasma gondii Memorias Do Instituto Oswaldo Cruz. 104: 201-210. PMID 19430645 DOI: 10.1590/S0074-02762009000200013  0.375
2009 Tait ED, Hunter CA. The Foxo and the hound: Chasing the in vivo regulation of T cell populations during infection Nature Immunology. 10: 457-458. PMID 19381139 DOI: 10.1038/Ni0509-457  0.409
2009 Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5748-56. PMID 19380822 DOI: 10.4049/Jimmunol.0801162  0.825
2009 Wilson EH, Harris TH, Mrass P, John B, Tait ED, Wu GF, Pepper M, Wherry EJ, Dzierzinski F, Roos D, Haydon PG, Laufer TM, Weninger W, Hunter CA. Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers. Immunity. 30: 300-11. PMID 19167248 DOI: 10.1016/J.Immuni.2008.12.013  0.831
2008 Wilson EH, Hunter CA. Immunodominance and recognition of intracellular pathogens. The Journal of Infectious Diseases. 198: 1579-81. PMID 18922096 DOI: 10.1086/593020  0.614
2008 John B, Hunter CA. Immunology: Neutrophil soldiers or Trojan horses? Science. 321: 917-918. PMID 18703727 DOI: 10.1126/Science.1162914  0.73
2008 Intlekofer AM, Banerjee A, Takemoto N, Gordon SM, Dejong CS, Shin H, Hunter CA, Wherry EJ, Lindsten T, Reiner SL. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science (New York, N.Y.). 321: 408-11. PMID 18635804 DOI: 10.1126/Science.1159806  0.628
2008 Silver JS, Hunter CA. With a little help from their friends: interleukin-21, T cells, and B cells. Immunity. 29: 7-9. PMID 18631451 DOI: 10.1016/J.Immuni.2008.06.005  0.642
2008 Pepper M, Dzierszinski F, Wilson E, Tait E, Fang Q, Yarovinsky F, Laufer TM, Roos D, Hunter CA. Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines. Journal of Immunology (Baltimore, Md. : 1950). 180: 6229-36. PMID 18424745 DOI: 10.4049/Jimmunol.180.9.6229  0.813
2008 Villarino AV, Artis D, Bezbradica JS, Miller O, Saris CJM, Joyce S, Hunter CA. IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD International Immunology. 20: 739-752. PMID 18375937 DOI: 10.1093/Intimm/Dxn032  0.792
2008 LaRosa DF, Stumhofer JS, Gelman AE, Rahman AH, Taylor DK, Hunter CA, Turka LA. T cell expression of MyD88 is required for resistance to Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 105: 3855-60. PMID 18308927 DOI: 10.1073/Pnas.0706663105  0.836
2008 Iparraguirre A, Tobias JW, Hensley SE, Masek KS, Cavanagh LL, Rendl M, Hunter CA, Ertl HC, von Andrian UH, Weninger W. Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide. Journal of Leukocyte Biology. 83: 610-20. PMID 18029397 DOI: 10.1189/Jlb.0807511  0.34
2008 John b, Hunter C. Dynamic imaging of CD8+ T cell interactions with dendritic cells during infection with Toxoplasma gondii The Faseb Journal. 22: 447-447. DOI: 10.1096/Fasebj.22.2_Supplement.447  0.475
2007 Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, Ernst M, Saris CJ, O'Shea JJ, Hunter CA. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nature Immunology. 8: 1363-71. PMID 17994025 DOI: 10.1038/Ni1537  0.857
2007 Dzierszinski F, Pepper M, Stumhofer JS, LaRosa DF, Wilson EH, Turka LA, Halonen SK, Hunter CA, Roos DS. Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infection and Immunity. 75: 5200-9. PMID 17846116 DOI: 10.1128/Iai.00954-07  0.854
2007 Hunter CA. Act1-ivating IL-17 inflammation Nature Immunology. 8: 232-234. PMID 17304231 DOI: 10.1038/Ni0307-232  0.353
2007 Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation Annual Review of Immunology. 25: 221-242. PMID 17291186 DOI: 10.1146/Annurev.Immunol.22.012703.104758  0.426
2007 Villarino AV, Tato CM, Stumhofer JS, Yao Z, Cui YK, Hennighausen L, O'Shea JJ, Hunter CA. Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals Journal of Experimental Medicine. 204: 65-71. PMID 17227909 DOI: 10.1084/Jem.20061198  0.839
2007 Stumhofer JS, Silver J, Laurence A, Porrett PM, Turka LA, Ernst M, Saris CJ, O′Shea JJ, Hunter CA. 146 A Central Role for Interleukin 27 and IL-6 Mediated Activation of STAT3 in T Cell Production of IL-10 Cytokine. 39: 40-41. DOI: 10.1016/J.Cyto.2007.07.151  0.846
2007 Silver J, Ernst M, Hunter C. 140 Mutation of the SOCS3 Binding Site of gp130 Confers Acute Susceptibility to Toxoplasma gondii Infection Cytokine. 39: 39-39. DOI: 10.1016/J.Cyto.2007.07.145  0.605
2006 Masek KS, Fiore J, Leitges M, Yan SF, Freedman BD, Hunter CA. Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii Journal of Cell Science. 119: 4565-4573. PMID 17074836 DOI: 10.1242/Jcs.03206  0.364
2006 Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, Saris CJ, O'Shea JJ, Hennighausen L, Ernst M, Hunter CA. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nature Immunology. 7: 937-45. PMID 16906166 DOI: 10.1038/Ni1376  0.864
2006 Wilson EH, Zaph C, Mohrs M, Welcher A, Siu J, Artis D, Hunter CA. B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses Journal of Immunology. 177: 2365-2372. PMID 16887998 DOI: 10.4049/Jimmunol.177.4.2365  0.776
2006 Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. The Journal of Clinical Investigation. 116: 1317-26. PMID 16670771 DOI: 10.1172/Jci25308  0.741
2006 Owyang AM, Zaph C, Wilson EH, Guild KJ, McClanahan T, Miller HR, Cua DJ, Goldschmidt M, Hunter CA, Kastelein RA, Artis D. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. The Journal of Experimental Medicine. 203: 843-9. PMID 16606667 DOI: 10.1084/Jem.20051496  0.77
2006 Tato CM, Mason N, Artis D, Shapira S, Caamano JC, Bream JH, Liou HC, Hunter CA. Opposing roles of NF-κB family members in the regulation of NK cell proliferation and production of IFN-γ International Immunology. 18: 505-513. PMID 16481345 DOI: 10.1093/Intimm/Dxh391  0.819
2006 Rosas LE, Satoskar AA, Roth KM, Keiser TL, Barbi J, Hunter C, De Sauvage FJ, Satoskar AR. Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to Leishmania donovani infection but develop severe liver immunopathology American Journal of Pathology. 168: 158-169. PMID 16400019 DOI: 10.2353/Ajpath.2006.050013  0.562
2006 Villarino AV, Stumhofer JS, Saris CJM, Kastelein RA, De Sauvage FJ, Hunter CA. IL-27 limits IL-2 production during Th1 differentiation Journal of Immunology. 176: 237-247. PMID 16365415 DOI: 10.4049/Jimmunol.176.1.237  0.827
2005 Corn RA, Hunter C, Liou HC, Siebenlist U, Boothby MR. Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation. Journal of Immunology (Baltimore, Md. : 1950). 175: 2102-10. PMID 16081776 DOI: 10.4049/Jimmunol.175.4.2102  0.556
2005 Shapira S, Harb OS, Margarit J, Matrajt M, Han J, Hoffmann A, Freedman B, May MJ, Roos DS, Hunter CA. Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii. Journal of Cell Science. 118: 3501-8. PMID 16079291 DOI: 10.1242/Jcs.02428  0.742
2005 Wilson EH, Wille-Reece U, Dzierszinski F, Hunter CA. A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. Journal of Neuroimmunology. 165: 63-74. PMID 16005735 DOI: 10.1016/J.Jneuroim.2005.04.018  0.703
2005 Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions Nature Reviews Immunology. 5: 521-531. PMID 15999093 DOI: 10.1038/Nri1648  0.42
2005 Villarino AV, Larkin J, Saris CJ, Caton AJ, Lucas S, Wong T, de Sauvage FJ, Hunter CA. Positive and negative regulation of the IL-27 receptor during lymphoid cell activation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7684-91. PMID 15944269 DOI: 10.4049/Jimmunol.174.12.7684  0.78
2005 Artis D, Kane CM, Fiore J, Zaph C, Shapira S, Joyce K, Macdonald A, Hunter C, Scott P, Pearce EJ. Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7154-9. PMID 15905559 DOI: 10.4049/Jimmunol.174.11.7154  0.843
2005 Aronson LR, Drobatz KJ, Hunter CA, Mason N. Effects of CD28 blockade on subsets of naïve T cells in cats. American Journal of Veterinary Research. 66: 483-92. PMID 15822594 DOI: 10.2460/Ajvr.2005.66.483  0.718
2005 Sun J, Walsh M, Villarino AV, Cervi L, Hunter CA, Choi Y, Pearce EJ. TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development. Journal of Immunology (Baltimore, Md. : 1950). 174: 742-51. PMID 15634894 DOI: 10.4049/Jimmunol.174.2.742  0.747
2005 Hunter CA, Villarino A, Artis D, Scott P. The role of IL-27 in the development of T-cell responses during parasitic infections. Immunological Reviews. 202: 106-14. PMID 15546389 DOI: 10.1111/J.0105-2896.2004.00213.X  0.816
2004 Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA, Pearce EJ. Helminth antigens modulate TLR-initiated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 173: 7454-61. PMID 15585871 DOI: 10.4049/Jimmunol.173.12.7454  0.781
2004 Pepper M, Dzierszinski F, Crawford A, Hunter CA, Roos D. Development of a system to study CD4+-T-cell responses to transgenic ovalbumin-expressing Toxoplasma gondii during toxoplasmosis. Infection and Immunity. 72: 7240-6. PMID 15557649 DOI: 10.1128/Iai.72.12.7240-7246.2004  0.751
2004 Lieberman LA, Villegas EN, Hunter CA. Interleukin-15-deficient mice develop protective immunity to Toxoplasma gondii Infection and Immunity. 72: 6729-6732. PMID 15501812 DOI: 10.1128/Iai.72.11.6729-6732.2004  0.863
2004 Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, Summer S, Covey TM, Huang E, Yoshida H, Koretzky G, Goldschmidt M, Wu GD, de Sauvage F, Miller HR, ... ... Hunter CA, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. Journal of Immunology (Baltimore, Md. : 1950). 173: 5626-34. PMID 15494513 DOI: 10.4049/Jimmunol.173.9.5626  0.812
2004 Mason NJ, Fiore J, Kobayashi T, Masek KS, Choi Y, Hunter CA. TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii. Infection and Immunity. 72: 5662-7. PMID 15385464 DOI: 10.1128/Iai.72.10.5662-5667.2004  0.717
2004 Villarino AV, Hunter CA. Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27 Arthritis Research and Therapy. 6: 225-233. PMID 15380038 DOI: 10.1186/Ar1227  0.719
2004 Mason NJ, Artis D, Hunter CA. New lessons from old pathogens: What parasitic infections have taught us about the role of nuclear factor-κB in the regulation of immunity Immunological Reviews. 201: 48-56. PMID 15361232 DOI: 10.1111/J.0105-2896.2004.00189.X  0.766
2004 Lieberman LA, Cardillo F, Owyang AM, Rennick DM, Cua DJ, Kastelein RA, Hunter CA. IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12. Journal of Immunology (Baltimore, Md. : 1950). 173: 1887-93. PMID 15265921 DOI: 10.4049/Jimmunol.173.3.1887  0.75
2004 Tato CM, Martins GA, High FA, DiCioccio CB, Reiner SL, Hunter CA. Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. Journal of Immunology (Baltimore, Md. : 1950). 173: 1514-7. PMID 15265878 DOI: 10.4049/Jimmunol.173.3.1514  0.703
2004 Villarino AV, Huang E, Hunter CA. Understanding the pro- and anti-inflammatory properties of IL-27 Journal of Immunology. 173: 715-720. PMID 15240655 DOI: 10.4049/Jimmunol.173.2.715  0.713
2004 Sague SL, Tato C, Puré E, Hunter CA. The regulation and activation of CD44 by natural killer (NK) cells and its role in the production of IFN-gamma. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 301-9. PMID 15153314 DOI: 10.1089/107999004323065093  0.723
2004 Artis D, Johnson LM, Joyce K, Saris C, Villarino A, Hunter CA, Scott P. Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 172: 4672-5. PMID 15067040 DOI: 10.4049/Jimmunol.172.8.4672  0.793
2004 Wilson EH, Hunter CA. The role of astrocytes in the immunopathogenesis of toxoplasmic encephalitis. International Journal For Parasitology. 34: 543-8. PMID 15064118 DOI: 10.1016/J.Ijpara.2003.12.010  0.645
2004 Shapira S, Harb OS, Caamano J, Hunter CA. The NF-κB signaling pathway: immune evasion and immunoregulation during toxoplasmosis International Journal For Parasitology. 34: 393-400. PMID 15055212 DOI: 10.1016/J.Ijpara.2003.12.005  0.758
2004 Mason NJ, Liou HC, Hunter CA. T Cell-Intrinsic Expression of c-Rel Regulates Th1 Cell Responses Essential for Resistance to Toxoplasma gondii Journal of Immunology. 172: 3704-3711. PMID 15004174 DOI: 10.4049/Jimmunol.172.6.3704  0.773
2004 Speirs K, Lieberman L, Caamano J, Hunter CA, Scott P. Cutting Edge: NF-κB2 Is a Negative Regulator of Dendritic Cell Function Journal of Immunology. 172: 752-756. PMID 14707043 DOI: 10.4049/Jimmunol.172.2.752  0.703
2004 Lieberman LA, Banica M, Reiner SL, Hunter CA. STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). 172: 457-63. PMID 14688355 DOI: 10.4049/Jimmunol.172.1.457  0.775
2003 Rankin EB, Yu D, Jiang J, Shen H, Pearce EJ, Goldschmidt MH, Levy DE, Golovkina TV, Hunter CA, Thomas-Tikhonenko A. An essential role of Th1 responses and interferon gamma in infection-mediated suppression of neoplastic growth. Cancer Biology & Therapy. 2: 687-93. PMID 14688478  0.366
2003 Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, Kastelein RA, Saris C, Hunter CA. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity. 19: 645-55. PMID 14614852 DOI: 10.1016/S1074-7613(03)00300-5  0.879
2003 Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, Zediak VP, Banica M, DiCioccio CB, Gross DA, Mao CA, Shen H, Cereb N, Yang SY, Lindsten T, Rossant J, ... Hunter CA, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, N.Y.). 302: 1041-3. PMID 14605368 DOI: 10.1126/Science.1090148  0.411
2003 Kobayashi T, Walsh PT, Walsh MC, Speirs KM, Chiffoleau E, King CG, Hancock WW, Caamano JH, Hunter CA, Scott P, Turka LA, Choi Y. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity. 19: 353-63. PMID 14499111 DOI: 10.1016/S1074-7613(03)00230-9  0.591
2003 Wilson EH, Hunter CA. Understanding the role of the CD40--CD40L interaction in resistance to parasitic infections. Parasite Immunology. 25: 179-83. PMID 12940960 DOI: 10.1046/J.1365-3024.2003.00624.X  0.574
2003 Hunter CA, Lieberman LA, Mason N, Pepper M, Sague SL, Tato C, Zediak V. Costimulation in resistance to infection and development of immune pathology: lessons from toxoplasma. Immunologic Research. 27: 331-40. PMID 12857979 DOI: 10.1385/Ir:27:2-3:331  0.816
2003 Zediak VP, Hunter CA. IL-10 fails to inhibit the production of IL-18 in response to inflammatory stimuli Cytokine. 21: 84-90. PMID 12670447 DOI: 10.1016/S1043-4666(03)00013-9  0.338
2003 Tato CM, Villarino A, Caamaño JH, Boothby M, Hunter CA. Inhibition of NF-κB Activity in T and NK Cells Results in Defective Effector Cell Expansion and Production of IFN-γ Required for Resistance to Toxoplasma gondii Journal of Immunology. 170: 3139-3146. PMID 12626571 DOI: 10.4049/Jimmunol.170.6.3139  0.842
2003 Artis D, Speirs K, Joyce K, Goldschmidt M, Caamaño J, Hunter CA, Scott P. NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 170: 1995-2003. PMID 12574369 DOI: 10.4049/Jimmunol.170.4.1995  0.724
2002 Lieberman LA, Hunter CA. Regulatory pathways involved in the infection-induced production of IFN-γ by NK cells Microbes and Infection. 4: 1531-1538. PMID 12505525 DOI: 10.1016/S1286-4579(02)00036-9  0.723
2002 Lieberman LA, Hunter CA. The role of cytokines and their signaling pathways in the regulation of immunity to Toxoplasma gondii International Reviews of Immunology. 21: 373-403. PMID 12486820 DOI: 10.1080/08830180213281  0.718
2002 Wille U, Villegas EN, Craig L, Peach R, Hunter CA. Contribution of Interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 Ligand Pathways to the Development of a Pathological T-Cell Response in IL-10-Deficient Mice Infection and Immunity. 70: 6940-6947. PMID 12438373 DOI: 10.1128/Iai.70.12.6940-6947.2002  0.783
2002 Artis D, Shapira S, Mason N, Speirs KM, Goldschmidt M, Caamaño J, Liou HC, Hunter CA, Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4481-7. PMID 12370384 DOI: 10.4049/Jimmunol.169.8.4481  0.832
2002 Hilliard BA, Mason N, Xu L, Sun J, Lamhamedi-Cherradi SE, Liou HC, Hunter C, Chen YH. Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation. The Journal of Clinical Investigation. 110: 843-50. PMID 12235116 DOI: 10.1172/Jci15254  0.755
2002 Villegas EN, Lieberman LA, Carding SR, Hunter CA. Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon. Infection and Immunity. 70: 4757-61. PMID 12183516 DOI: 10.1128/Iai.70.9.4757-4761.2002  0.873
2002 Villegas EN, Lieberman LA, Mason N, Blass SL, Zediak VP, Peach R, Horan T, Yoshinaga S, Hunter CA. A role for inducible costimulator protein in the CD28- independent mechanism of resistance to Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 169: 937-43. PMID 12097399 DOI: 10.4049/Jimmunol.169.2.937  0.83
2002 Scott P, Hunter CA. Dendritic cells and immunity to leishmaniasis and toxoplasmosis Current Opinion in Immunology. 14: 466-470. PMID 12088681 DOI: 10.1016/S0952-7915(02)00353-9  0.342
2002 Speirs K, Caamano J, Goldschmidt MH, Hunter CA, Scott P. NF-κB2 Is Required for Optimal CD40-Induced IL-12 Production but Dispensable for Th1 Cell Differentiation Journal of Immunology. 168: 4406-4413. PMID 11970983 DOI: 10.4049/Jimmunol.168.9.4406  0.366
2002 Jones DE, Ackermann MR, Wille U, Hunter CA, Scott P. Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection. Infection and Immunity. 70: 2151-8. PMID 11895981 DOI: 10.1128/Iai.70.4.2151-2158.2002  0.418
2002 Mason N, Aliberti J, Caamano JC, Liou HC, Hunter CA. Cutting edge: identification of c-Rel-dependent and -independent pathways of IL-12 production during infectious and inflammatory stimuli. Journal of Immunology (Baltimore, Md. : 1950). 168: 2590-4. PMID 11884420 DOI: 10.4049/Jimmunol.168.6.2590  0.727
2001 Wysocka M, Robertson S, Riemann H, Caamano J, Hunter C, Mackiewicz A, Montaner LJ, Trinchieri G, Karp CL. IL-12 suppression during experimental endotoxin tolerance: dendritic cell loss and macrophage hyporesponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 166: 7504-13. PMID 11390504 DOI: 10.4049/Jimmunol.166.12.7504  0.535
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