375 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Mahmoudi Aliabadi P, Teuber R, Jani PK, Wilson L, Enghard P, Barnes S, Chiorazzi N, Radbruch A, Melchers F, Kubagawa H. Soluble Fc Receptor for IgM in Sera From Subsets of Patients With Chronic Lymphocytic Leukemia as Determined by a New Mouse Monoclonal Antibody. Frontiers in Immunology. 13: 863895. PMID 35784336 DOI: 10.3389/fimmu.2022.863895  0.315
2021 Rincon-Arevalo H, Wiedemann A, Stefanski AL, Lettau M, Szelinski F, Fuchs S, Frei AP, Steinberg M, Kam-Thong T, Hatje K, Keller B, Warnatz K, Radbruch A, Lino AC, Schrezenmeier E, et al. Deep Phenotyping of CD11c B Cells in Systemic Autoimmunity and Controls. Frontiers in Immunology. 12: 635615. PMID 33777025 DOI: 10.3389/fimmu.2021.635615  0.302
2020 Ostendorf L, Burns M, Durek P, Heinz GA, Heinrich F, Garantziotis P, Enghard P, Richter U, Biesen R, Schneider U, Knebel F, Burmester G, Radbruch A, Mei HE, Mashreghi MF, et al. Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus. The New England Journal of Medicine. 383: 1149-1155. PMID 32937047 DOI: 10.1056/Nejmoa2023325  0.438
2020 Cornelis R, Hahne S, Taddeo A, Petkau G, Malko D, Durek P, Thiem M, Heiberger L, Peter L, Mohr E, Klaeden C, Tokoyoda K, Siracusa F, Hoyer BF, Hiepe F, ... ... Radbruch A, et al. Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells. Cell Reports. 32: 107982. PMID 32755576 DOI: 10.1016/J.Celrep.2020.107982  0.354
2020 Abdirama D, Tesch S, Grießbach AS, von Spee-Mayer C, Humrich JY, Stervbo U, Babel N, Meisel C, Alexander T, Biesen R, Bacher P, Scheffold A, Eckardt KU, Hiepe F, Radbruch A, et al. Nuclear antigen-reactive CD4 T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys. Kidney International. PMID 32592813 DOI: 10.1016/J.Kint.2020.05.051  0.441
2020 Riedel R, Addo R, Ferreira-Gomes M, Heinz GA, Heinrich F, Kummer J, Greiff V, Schulz D, Klaeden C, Cornelis R, Menzel U, Kröger S, Stervbo U, Köhler R, Haftmann C, ... ... Radbruch A, et al. Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nature Communications. 11: 2570. PMID 32444631 DOI: 10.1038/S41467-020-16464-6  0.378
2020 Gryzik S, Hoang Y, Lischke T, Mohr E, Venzke M, Kadner I, Poetzsch J, Groth D, Radbruch A, Hutloff A, Baumgrass R. Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception. Elife. 9. PMID 32441253 DOI: 10.7554/Elife.53226  0.452
2020 Alexander T, Badoglio M, Henes J, Heesen C, Arnold R, Radbruch A, Snowden JA, Hiepe F. [Autologous hematopoietic stem cell transplantation for autoimmune diseases : Current indications and mode of action, a review on behalf of the EBMT Autoimmune Diseases Working Party (ADWP)]. Zeitschrift Fur Rheumatologie. 79: 419-428. PMID 32356079 DOI: 10.1007/S00393-020-00795-2  0.325
2020 Beller A, Kruglov A, Durek P, von Goetze V, Werner K, Heinz GA, Ninnemann J, Lehmann K, Maier R, Hoffmann U, Riedel R, Heiking K, Zimmermann J, Siegmund B, Mashreghi MF, ... Radbruch A, et al. Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer's patches in mice. European Journal of Immunology. PMID 32065660 DOI: 10.1002/Eji.201948474  0.355
2020 Radbruch A. Review for "Human T cells interacting with HNSCC‐derived mesenchymal stromal cells acquire Tissue‐Resident memory like properties" European Journal of Immunology. DOI: 10.1002/Eji.202048544/V1/Review1  0.382
2019 Sarkander J, Hojyo S, Mursell M, Yamasaki Y, Wu TY, Tumes DJ, Miyauchi K, Tran CL, Zhu J, Löhning M, Hutloff A, Mashreghi MF, Kubo M, Radbruch A, Tokoyoda K. Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location. Frontiers in Immunology. 10: 3113. PMID 32010148 DOI: 10.3389/Fimmu.2019.03113  0.423
2019 Cheng Q, Pelz A, Taddeo A, Khodadadi L, Klotsche J, Hoyer BF, Alexander T, Thiel A, Burmester GR, Radbruch A, Hiepe F. Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies. European Journal of Immunology. PMID 31714996 DOI: 10.1002/Eji.201948144  0.362
2019 Chang HD, Tokoyoda K, Hoyer B, Alexander T, Khodadadi L, Mei H, Dörner T, Hiepe F, Burmester GR, Radbruch A. Pathogenic memory plasma cells in autoimmunity. Current Opinion in Immunology. 61: 86-91. PMID 31675681 DOI: 10.1016/J.Coi.2019.09.005  0.346
2019 Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology. 49: 1457-1973. PMID 31633216 DOI: 10.1002/Eji.201970107  0.303
2019 Karl M, Sommer C, Gabriel CH, Hecklau K, Venzke M, Hennig AF, Radbruch A, Selbach M, Baumgrass R. Recruitment of Histone Methyltransferase Ehmt1 to Foxp3 TSDR Counteracts Differentiation of Induced Regulatory T Cells. Journal of Molecular Biology. PMID 31362003 DOI: 10.1016/J.Jmb.2019.07.031  0.364
2019 Shebzukhov Y, Holtze S, Hirseland H, Schäfer H, Radbruch A, Hildebrandt T, Grützkau A. Identification of cross-reactive antibodies for the detection of lymphocytes, myeloid cells and haematopoietic precursors in the naked mole rat. European Journal of Immunology. PMID 31349374 DOI: 10.1002/Eji.201948124  0.361
2019 Addo RK, Heinrich F, Heinz GA, Schulz D, Sercan-Alp Ö, Lehmann K, Tran CL, Bardua M, Matz M, Löhning M, Hauser AE, Kruglov A, Chang HD, Durek P, Radbruch A, et al. Single-cell transcriptomes of murine bone marrow stromal cells Reveal niche-associated heterogeneity. European Journal of Immunology. PMID 31149730 DOI: 10.1002/Eji.201848053  0.454
2019 Hradilkova K, Maschmeyer P, Westendorf K, Schliemann H, Husak O, von Stuckrad SL, Kallinich T, Minden K, Durek P, Grün JR, Chang HD, Radbruch A. T helper lymphocytes of chronic inflammation are maintained by fatty acid oxidation and adapt to it through Twist1. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31131995 DOI: 10.1002/Art.40939  0.325
2019 Kubagawa H, Honjo K, Ohkura N, Sakaguchi S, Radbruch A, Melchers F, Jani PK. Functional Roles of the IgM Fc Receptor in the Immune System. Frontiers in Immunology. 10: 945. PMID 31130948 DOI: 10.3389/Fimmu.2019.00945  0.39
2019 Tonon S, Mion F, Dong J, Chang HD, Dalla E, Scapini P, Perruolo G, Zanello A, Dugo M, Cassatella MA, Colombo MP, Radbruch A, Tripodo C, Pucillo CE. IL-10-producing B cells are characterized by a specific methylation signature. European Journal of Immunology. PMID 31034584 DOI: 10.1002/Eji.201848025  0.374
2019 Khodadadi L, Cheng Q, Radbruch A, Hiepe F. The Maintenance of Memory Plasma Cells. Frontiers in Immunology. 10: 721. PMID 31024553 DOI: 10.3389/Fimmu.2019.00721  0.366
2019 Männe C, Takaya A, Yamasaki Y, Mursell M, Hojyo S, Wu TY, Sarkander J, McGrath MA, Cornelis R, Hahne S, Cheng Q, Kawamoto T, Hiepe F, Kaufmann SHE, Yamamoto T, ... Radbruch A, et al. SiiE prevents an efficient humoral immune memory by interfering with IgG plasma cell persistence in the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910977 DOI: 10.1073/Pnas.1818242116  0.391
2019 Siracusa F, Durek P, McGrath MA, Sercan-Alp Ö, Rao A, Du W, Cendón C, Chang HD, Heinz GA, Mashreghi MF, Radbruch A, Dong J. CD69 memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue-resident memory T lymphocytes. European Journal of Immunology. PMID 30673129 DOI: 10.1002/Eji.201847982  0.36
2019 Cheng Q, Pelz A, Hoyer BF, Khodadadi L, Alexander T, Burmester GR, Radbruch A, Hiepe F. Ab0028 Selective Depletion Of Plasma Cells In Vivobased On Specificity Of Secreted Antibodies Annals of the Rheumatic Diseases. 78: 1479-1479. DOI: 10.1136/Annrheumdis-2019-Eular.8150  0.4
2019 Cheng Q, Pelz A, Taddeo A, Khodadadi L, Klotsche J, Hoyer BF, Alexander T, Thiel A, Burmester G, Radbruch A, Hiepe F. Author response for "Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies" European Journal of Immunology. DOI: 10.1002/Eji.201948144/V2/Response1  0.36
2019 Addo RK, Heinrich F, Heinz GA, Schulz D, Sercan‐Alp Ö, Lehmann K, Tran CL, Bardua M, Matz M, Löhning M, Hauser AE, Kruglov A, Chang H, Durek P, Radbruch A, et al. Author response for "Single‐cell transcriptomes of murine bone marrow stromal cells Reveal niche‐associated heterogeneity" European Journal of Immunology. DOI: 10.1002/Eji.201848053/V2/Response1  0.307
2019 Tonon S, Mion F, Dong J, Chang H, Dalla E, Scapini P, Perruolo G, Zanello A, Dugo M, Cassatella MA, Colombo MP, Radbruch A, Tripodo C, Pucillo CE. Author response for "IL‐10‐producing B cells are characterized by a specific methylation signature" European Journal of Immunology. DOI: 10.1002/Eji.201848025/V2/Response1  0.33
2018 Bardua M, Haftmann C, Durek P, Westendorf K, Buttgereit A, Tran CL, McGrath M, Weber M, Lehmann K, Addo RK, Heinz GA, Stittrich AB, Maschmeyer P, Radbruch H, Lohoff M, ... ... Radbruch A, et al. MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes. Frontiers in Immunology. 9: 2813. PMID 30574141 DOI: 10.3389/Fimmu.2018.02813  0.379
2018 Schulte-Wrede U, Sörensen T, Grün JR, Häupl T, Hirseland H, Steinbrich-Zöllner M, Wu P, Radbruch A, Poddubnyy D, Sieper J, Syrbe U, Grützkau A. An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus. Arthritis Research & Therapy. 20: 191. PMID 30157966 DOI: 10.1186/S13075-018-1692-Y  0.303
2018 Alexander T, Cheng Q, Klotsche J, Khodadadi L, Waka A, Biesen R, Hoyer BF, Burmester GR, Radbruch A, Hiepe F. Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors. European Journal of Immunology. PMID 29979809 DOI: 10.1002/Eji.201847492  0.425
2018 Giesecke C, Meyer T, Durek P, Maul J, Preiß J, Jacobs JFM, Thiel A, Radbruch A, Ullrich R, Dörner T. Simultaneous Presence of Non- and Highly Mutated Keyhole Limpet Hemocyanin (KLH)-Specific Plasmablasts Early after Primary KLH Immunization Suggests Cross-Reactive Memory B Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29735481 DOI: 10.4049/Jimmunol.1701728  0.377
2018 Chang HD, Tokoyoda K, Radbruch A. Immunological memories of the bone marrow. Immunological Reviews. 283: 86-98. PMID 29664564 DOI: 10.1111/Imr.12656  0.355
2018 Cheng Q, Khodadadi L, Taddeo A, Klotsche J, Hoyer BF, Radbruch A, Hiepe F. CXCR4-CXCL12 interaction is important for plasma cell homing and survival in NZB/W mice. European Journal of Immunology. PMID 29427452 DOI: 10.1002/Eji.201747023  0.341
2018 Siracusa F, McGrath MA, Maschmeyer P, Bardua M, Lehmann K, Heinz G, Durek P, Heinrich FF, Mashreghi MF, Chang HD, Tokoyoda K, Radbruch A. Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358404 DOI: 10.1073/Pnas.1715618115  0.425
2018 Alexander T, Hoyer B, Cheng Q, Khodadadi L, Taddeo A, Klotsche J, Thiel A, Burmester G, Radbruch A, Arnold R, Hiepe F. S1D:6 Targeting plasma cells and their precursors by immunoablation versus bortezomib plus rituximab in systemic lupus erythemtosus Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Abstract.6  0.388
2018 Martin J, Cheng Q, Laurent S, Thaler F, Meinl E, Radbruch A, Hiepe F. PS1:10 Effects of belimumab treatment on b cell hyperactivity and type-i interferon expression in patients with systemic lupus erythematosus Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Abstract.59  0.389
2018 Abdirama D, Tesch S, Griessbach A, Scheffold A, Radbruch A, Stervbo U, Babel N, Burmester G, Humrich J, Riemekasten G, Enghard P. PS5:101 Nuclear antigen-reactive cd4+ t cells are expanded in active sle, correlate with disease activity, invade target organs such as the kidneys, and outnumber their regulatory counterparts Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Abstract.146  0.461
2018 Alexander T, Haftmann C, Riedel R, Templin L, Burmester G, Radbruch A, Hiepe F, Mashreghi F. PS5:90 Enhanced il-7 receptor signalling in sle promotes t-helper cell proliferation through upregulation of microrna-182 and downregulation of foxo1 Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Abstract.135  0.395
2018 Shebzukhov Y, Holtze S, Hirseland H, Schäfer H, Radbruch A, Hildebrandt T, Grützkau A. Author response for "Identification of cross‐reactive antibodies for the detection of lymphocytes, myeloid cells and haematopoietic precursors in the naked mole rat" European Journal of Immunology. DOI: 10.1002/Eji.201948124/V2/Response1  0.339
2018 Siracusa F, Durek P, McGrath MA, Sercan-Alp Ö, Rao A, Du W, Cendón C, Chang H, Heinz GA, Mashreghi M, Radbruch A, Dong J. Author response for "CD69 + memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue-resident memory T lymphocytes" European Journal of Immunology. DOI: 10.1002/Eji.201847982/V2/Response1  0.358
2017 Maschmeyer P, Petkau G, Siracusa F, Zimmermann J, Zügel F, Kühl AA, Lehmann K, Schimmelpfennig S, Weber M, Haftmann C, Riedel R, Bardua M, Heinz GA, Tran CL, Hoyer BF, ... ... Radbruch A, et al. Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo. Journal of Autoimmunity. PMID 29183643 DOI: 10.1016/J.Jaut.2017.11.005  0.351
2017 Lindner J, Rausch S, Treptow S, Geldmeyer-Hilt K, Krause T, St-Arnaud R, Arabian A, Radbruch A, Hartmann S, Worm M, Heine G. Endogenous Calcitriol Synthesis Controls the Humoral IgE Response in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 29109124 DOI: 10.4049/Jimmunol.1602080  0.371
2017 Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology. 47: 1584-1797. PMID 29023707 DOI: 10.1002/Eji.201646632  0.554
2017 Zimmermann J, Durek P, Kühl AA, Schattenberg F, Maschmeyer P, Siracusa F, Lehmann K, Westendorf K, Weber M, Riedel R, Müller S, Radbruch A, Chang HD. The intestinal microbiota determines the colitis-inducing potential of T-bet-deficient Th cells in mice. European Journal of Immunology. PMID 28875499 DOI: 10.1002/Eji.201747100  0.373
2017 Schmitt V, Hahn M, Kästele V, Wagner O, Wiendl M, Derer A, Taddeo A, Hahne S, Radbruch A, Jäck HM, Schuh W, Mielenz D, Gay S, Schett G, Hueber AJ, et al. Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts. European Journal of Immunology. PMID 28857172 DOI: 10.1002/Eji.201646788  0.348
2017 Siracusa F, Alp ÖS, Maschmeyer P, McGrath M, Mashreghi MF, Hojyo S, Chang HD, Tokoyoda K, Radbruch A. Maintenance of CD8(+) memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation. European Journal of Immunology. PMID 28815584 DOI: 10.1002/Eji.201747063  0.375
2017 Greiff V, Menzel U, Miho E, Weber C, Riedel R, Cook S, Valai A, Lopes T, Radbruch A, Winkler TH, Reddy ST. Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development. Cell Reports. 19: 1467-1478. PMID 28514665 DOI: 10.1016/J.Celrep.2017.04.054  0.41
2017 Hoyer BF, Radbruch A. Protective and pathogenic memory plasma cells. Immunology Letters. 189: 10-12. PMID 28455167 DOI: 10.1016/J.Imlet.2017.04.014  0.397
2017 Strauß R, Rose T, Flint SM, Klotsche J, Häupl T, Peck-Radosavljevic M, Yoshida T, Kyogoku C, Flechsig A, Becker AM, Dao KH, Radbruch A, Burmester GR, Lyons PA, Davis LS, et al. Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options. Journal of Molecular Medicine (Berlin, Germany). PMID 28357476 DOI: 10.1007/S00109-017-1515-7  0.318
2017 Klocke J, Kopetschke K, Grießbach AS, Langhans V, Humrich JY, Biesen R, Dragun D, Radbruch A, Burmester GR, Riemekasten G, Enghard P. Mapping urinary chemokines in human lupus nephritis: Potentially redundant pathways recruit CD4and CD8T cells and macrophages. European Journal of Immunology. 47: 180-192. PMID 27753073 DOI: 10.1002/Eji.201646387  0.386
2017 Humrich JY, Spee-Mayer Cv, Siegert E, Bertolo M, Abdirama D, Rose A, Enghard P, Hiepe F, Alexander T, Radbruch A, Burmester G, Riemekasten G. 06.08 Low-dose il-2 therapy in refractory sle: results from a single centre phase i/iia clinical trial Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211053.8  0.366
2017 Alexander T, Cheng Q, Klotsche J, Hoyer B, Taddeo A, Waka A, Kühl AA, Burmester GR, Radbruch A, Hiepe F. 06.14 Proteasome inhibition with bortezomib in sle promotes therapeutically relevant depletion of short- and long-lived plasma cells but does not prevent their regeneration Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211053.14  0.432
2017 Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Sörensen T, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, et al. 05.08 Increased turnover of monocytes in patients with rheumatoid arthritis identified by transcriptome and cytometric profiling Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211052.8  0.338
2017 Alexander T, Haftmann C, Riedel R, Templin L, Humrich J, Burmester G, Radbruch A, Hiepe F, Mashreghi M. 02.34 Enhanced conventional cd4+ t cell proliferation in sle is associated with up-regulation of microrna-182 and increased il-7 receptor signalling Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211050.34  0.399
2017 Zimmermann J, Radbruch A, Chang H. 01.07 Control of chronic inflammation by t-bet expressed in th cells Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2016-211048.7  0.372
2016 Fuhrmann F, Lischke T, Gross F, Scheel T, Bauer L, Kalim KW, Radbruch A, Herzel H, Hutloff A, Baumgrass R. Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model. Elife. 5. PMID 28035902 DOI: 10.7554/Elife.20616  0.392
2016 Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T. Corrigendum: Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming. Nature Medicine. 22: 1502. PMID 27923028 DOI: 10.1038/Nm1216-1502A  0.36
2016 Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, ... ... Radbruch A, et al. Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development. Immunity. 45: 1148-1161. PMID 27851915 DOI: 10.1016/J.Immuni.2016.10.022  0.406
2016 Gabriel CH, Gross F, Karl M, Stephanowitz H, Hennig AF, Weber M, Gryzik S, Bachmann I, Hecklau K, Wienands J, Schuchhardt J, Herzel H, Radbruch A, Krause E, Baumgrass R. Identification of Novel Nuclear Factor of Activated T Cells (NFAT)-Associated Proteins in T cells. The Journal of Biological Chemistry. PMID 27637333 DOI: 10.1074/Jbc.M116.739326  0.337
2016 Sercan-Alp Ö, Radbruch A. Response: Commentary: Memory CD8(+) T Cells Colocalize with IL-7(+) Stromal Cells in Bone Marrow and Rest in Terms of Proliferation and Transcription. Frontiers in Immunology. 7: 329. PMID 27628561 DOI: 10.3389/Fimmu.2016.00329  0.429
2016 Durlanik S, Loyal L, Stark R, Sercan Alp Ö, Hartung A, Radbruch A, von Herrath M, Matzmohr N, Frentsch M, Thiel A. CD40L expression by CD4but not CD8T cells regulates antiviral immune responses in acute LCMV infection in mice. European Journal of Immunology. 46: 2566-2573. PMID 27562840 DOI: 10.1002/Eji.201646420  0.441
2016 Japp AS, Hoffmann K, Schlickeiser S, Glauben R, Nikolaou C, Maecker HT, Braun J, Matzmohr N, Sawitzki B, Siegmund B, Radbruch A, Volk HD, Frentsch M, Kunkel D, Thiel A. Wild immunology assessed by multidimensional mass cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 27403624 DOI: 10.1002/Cyto.A.22906  0.35
2016 Kieback E, Hilgenberg E, Stervbo U, Lampropoulou V, Shen P, Bunse M, Jaimes Y, Boudinot P, Radbruch A, Klemm U, Kühl AA, Liblau R, Hoevelmeyer N, Anderton SM, Uckert W, et al. Thymus-Derived Regulatory T Cells Are Positively Selected on Natural Self-Antigen through Cognate Interactions of High Functional Avidity. Immunity. 44: 1114-1126. PMID 27192577 DOI: 10.1016/J.Immuni.2016.04.018  0.443
2016 Alp ÖS, Radbruch A. The lifestyle of memory CD8(+) T cells. Nature Reviews. Immunology. 16: 271. PMID 26996198 DOI: 10.1038/Nri.2016.32  0.377
2016 Hiepe F, Radbruch A. Plasma cells as an innovative target in autoimmune disease with renal manifestations. Nature Reviews. Nephrology. 12: 232-40. PMID 26923204 DOI: 10.1038/Nrneph.2016.20  0.408
2016 Hojyo S, Sarkander J, Männe C, Mursell M, Hanazawa A, Zimmel D, Zhu J, Paul WE, Fillatreau S, Löhning M, Radbruch A, Tokoyoda K. B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow. Frontiers in Immunology. 7: 26. PMID 26870041 DOI: 10.3389/Fimmu.2016.00026  0.438
2016 Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM. Immunological memory: lessons from the past and a look to the future. Nature Reviews. Immunology. 16: 124-8. PMID 26831526 DOI: 10.1038/Nri.2016.13  0.483
2016 Bothur E, Raifer H, Haftmann C, Stittrich AB, Brüstle A, Brenner D, Bollig N, Bieringer M, Kang CH, Reinhard K, Camara B, Huber M, Visekruna A, Steinhoff U, Repenning A, ... ... Radbruch A, et al. Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. Nature Communications. 6: 8576. PMID 26815406 DOI: 10.1038/Ncomms9576  0.41
2016 Fuhrmann F, Lischke T, Gross F, Scheel T, Bauer L, Kalim KW, Radbruch A, Herzel H, Hutloff A, Baumgrass R. Author response: Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model Elife. DOI: 10.7554/Elife.20616.017  0.328
2016 Serra A, Khassawna TE, Petersen A, Schlundt C, Könnecke I, Schell H, Volk H, Radbruch A, Schmidt-Bleek K, Duda G. A4.01 T cells are critical regulators of soft callus mineralization and normal deposition of collagen I during bone repair Annals of the Rheumatic Diseases. 75. DOI: 10.1136/Annrheumdis-2016-209124.89  0.346
2016 Abdirama D, Enghard P, Tesch S, Radbruch A, Burmester G, Riemekasten G. A2.17 Detection of autoantigen-specific CD4+ T cells associated with systemic lupus erythematosus Annals of the Rheumatic Diseases. 75. DOI: 10.1136/Annrheumdis-2016-209124.52  0.426
2016 Humrich J, Spee-Mayer Cv, Siegert E, Bertolo M, Abdirama D, Rose A, Enghard P, Radbruch A, Burmester G, Riemekasten G. A7.06 Low-dose IL-2 therapy in refractory sle: Insights from a phase I/IIA clinical trial Annals of the Rheumatic Diseases. 75. DOI: 10.1136/Annrheumdis-2016-209124.137  0.333
2016 Tesch S, Grieβbach AS, Abdirama D, Stervbo U, Babel N, Radbruch A, Riemekasten G, Enghard P. P47 The Antirenal Autoreactive Cd4+ T Cell Response In Human Lupus Nephritis Kidney International Reports. 1. DOI: 10.1016/J.Ekir.2016.09.053  0.366
2015 Wilhelm TR, Taddeo A, Winter O, Schulz AR, Mälzer JN, Domingo C, Biesen R, Alexander T, Thiel A, Radbruch A, Hiepe F, Gerl V. Siglec-1-positive plasmacytoid dendritic cells (pDCs) in human peripheral blood: A semi-mature and myeloid-like subset imbalanced during protective and autoimmune responses. Clinical Immunology (Orlando, Fla.). PMID 26674280 DOI: 10.1016/J.Clim.2015.12.001  0.394
2015 von Spee-Mayer C, Siegert E, Abdirama D, Rose A, Klaus A, Alexander T, Enghard P, Sawitzki B, Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Humrich JY. Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases. PMID 26324847 DOI: 10.1136/Annrheumdis-2015-207776  0.389
2015 Fang Z, Hecklau K, Gross F, Bachmann I, Venzke M, Karl M, Schuchhardt J, Radbruch A, Herzel H, Baumgrass R. Transcription factor co-occupied regions in the murine genome constitute T-helper-cell subtype-specific enhancers. European Journal of Immunology. PMID 26300430 DOI: 10.1002/Eji.201545713  0.4
2015 Khodadadi L, Cheng Q, Alexander T, Sercan-Alp Ö, Klotsche J, Radbruch A, Hiepe F, Hoyer BF, Taddeo A. Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice. Plos One. 10: e0135081. PMID 26252021 DOI: 10.1371/Journal.Pone.0135081  0.412
2015 Taddeo A, Khodadadi L, Voigt C, Mumtaz IM, Cheng Q, Moser K, Alexander T, Manz RA, Radbruch A, Hiepe F, Hoyer BF. Long-lived plasma cells are early and constantly generated in New Zealand Black/New Zealand White F1 mice and their therapeutic depletion requires a combined targeting of autoreactive plasma cells and their precursors. Arthritis Research & Therapy. 17: 39. PMID 25889236 DOI: 10.1186/S13075-015-0551-3  0.336
2015 Mazzoni A, Santarlasci V, Maggi L, Capone M, Rossi MC, Querci V, De Palma R, Chang HD, Thiel A, Cimaz R, Liotta F, Cosmi L, Maggi E, Radbruch A, Romagnani S, et al. Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 3116-26. PMID 25740946 DOI: 10.4049/Jimmunol.1401303  0.408
2015 Alexander T, Sarfert R, Klotsche J, Kühl AA, Rubbert-Roth A, Lorenz HM, Rech J, Hoyer BF, Cheng Q, Waka A, Taddeo A, Wiesener M, Schett G, Burmester GR, Radbruch A, et al. The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus. Annals of the Rheumatic Diseases. 74: 1474-8. PMID 25710470 DOI: 10.1136/Annrheumdis-2014-206016  0.362
2015 Porstner M, Winkelmann R, Daum P, Schmid J, Pracht K, Côrte-Real J, Schreiber S, Haftmann C, Brandl A, Mashreghi MF, Gelse K, Hauke M, Wirries I, Zwick M, Roth E, ... Radbruch A, et al. miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2. European Journal of Immunology. 45: 1206-15. PMID 25678371 DOI: 10.1002/Eji.201444637  0.323
2015 Weber JP, Fuhrmann F, Feist RK, Lahmann A, Al Baz MS, Gentz LJ, Vu Van D, Mages HW, Haftmann C, Riedel R, Grün JR, Schuh W, Kroczek RA, Radbruch A, Mashreghi MF, et al. ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2. The Journal of Experimental Medicine. 212: 217-33. PMID 25646266 DOI: 10.1084/Jem.20141432  0.451
2015 Sercan Alp Ö, Durlanik S, Schulz D, McGrath M, Grün JR, Bardua M, Ikuta K, Sgouroudis E, Riedel R, Zehentmeier S, Hauser AE, Tsuneto M, Melchers F, Tokoyoda K, Chang HD, ... ... Radbruch A, et al. Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription. European Journal of Immunology. 45: 975-87. PMID 25639669 DOI: 10.1002/Eji.201445295  0.443
2015 Humrich JY, Spee-Mayer CV, Siegert E, Alexander T, Hiepe F, Radbruch A, Burmester GR, Riemekasten G. Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE Annals of the Rheumatic Diseases. 74: 791-792. PMID 25609413 DOI: 10.1136/Annrheumdis-2014-206506  0.327
2015 Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M. Individual T helper cells have a quantitative cytokine memory. Immunity. 42: 108-22. PMID 25607461 DOI: 10.1016/J.Immuni.2014.12.018  0.455
2015 Mei HE, Wirries I, Frölich D, Brisslert M, Giesecke C, Grün JR, Alexander T, Schmidt S, Luda K, Kühl AA, Engelmann R, Dürr M, Scheel T, Bokarewa M, Perka C, ... Radbruch A, et al. A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow. Blood. 125: 1739-48. PMID 25573986 DOI: 10.1182/Blood-2014-02-555169  0.356
2015 Zimmermann J, Radbruch A, Chang HD. A Ca(2+) concentration of 1.5 mM, as present in IMDM but not in RPMI, is critical for maximal response of Th cells to PMA/ionomycin. European Journal of Immunology. 45: 1270-3. PMID 25545753 DOI: 10.1002/Eji.201445247  0.379
2015 Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, ... ... Radbruch A, et al. miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. European Journal of Immunology. 45: 1192-205. PMID 25486906 DOI: 10.1002/Eji.201444633  0.331
2015 Taddeo A, Gerl V, Hoyer BF, Chang HD, Kohler S, Schaffert H, Thiel A, Radbruch A, Hiepe F. Selection and depletion of plasma cells based on the specificity of the secreted antibody. European Journal of Immunology. 45: 317-9. PMID 25263193 DOI: 10.1002/Eji.201444993  0.357
2015 Serra A, Könnecke I, Khassawna TE, Schlundt C, Schell H, Hauser A, Ellinghaus A, Volk H, Radbruch A, Duda G, Schmidt-Bleek K. A4.7 T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion Annals of the Rheumatic Diseases. 74. DOI: 10.1136/Annrheumdis-2015-207259.89  0.349
2015 Taddeo A, Hoyer B, Gerl V, Chang H, Pelz A, Kohler S, Radbruch A, Hiepe F. A8.28 Depletion of autoantibody-secreting plasma cells based on the specificity of the secreted antibody Annals of the Rheumatic Diseases. 74. DOI: 10.1136/Annrheumdis-2015-207259.213  0.429
2014 Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi MF, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kühl AA, Heimesaat MM, Esser C, Im SH, Radbruch A, Rutz S, et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. The Journal of Experimental Medicine. 211: 1807-19. PMID 25073792 DOI: 10.1084/Jem.20131548  0.368
2014 Köck J, Kreher S, Lehmann K, Riedel R, Bardua M, Lischke T, Jargosch M, Haftmann C, Bendfeldt H, Hatam F, Mashreghi MF, Baumgrass R, Radbruch A, Chang HD. Nuclear factor of activated t cells regulates the expression of interleukin-4 in Th2 cells in an All-or-none fashion Journal of Biological Chemistry. 289: 26752-26761. PMID 25037220 DOI: 10.1074/Jbc.M114.587865  0.417
2014 Heine G, Tabeling C, Hartmann B, Calera CRG, Kühl AA, Lindner J, Radbruch A, Witzenrath M, Worm M. 25-Hydroxvitamin D3 promotes the long-term effect of specific immunotherapy in a murine allergy model Journal of Immunology. 193: 1017-1023. PMID 24951815 DOI: 10.4049/Jimmunol.1301656  0.307
2014 Noster R, Riedel R, Mashreghi MF, Radbruch H, Harms L, Haftmann C, Chang HD, Radbruch A, Zielinski CE. IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells. Science Translational Medicine. 6: 241ra80. PMID 24944195 DOI: 10.1126/Scitranslmed.3008706  0.429
2014 Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, ... ... Radbruch A, et al. Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory. Proceedings of the National Academy of Sciences of the United States of America. 111: 9229-34. PMID 24927527 DOI: 10.1073/Pnas.1318731111  0.404
2014 Zehentmeier S, Roth K, Cseresnyes Z, Sercan Ö, Horn K, Niesner RA, Chang HD, Radbruch A, Hauser AE. Static and dynamic components synergize to form a stable survival niche for bone marrow plasma cells. European Journal of Immunology. 44: 2306-17. PMID 24777940 DOI: 10.1002/Eji.201344313  0.37
2014 Könnecke I, Serra A, El Khassawna T, Schlundt C, Schell H, Hauser A, Ellinghaus A, Volk HD, Radbruch A, Duda GN, Schmidt-Bleek K. T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion. Bone. 64: 155-65. PMID 24721700 DOI: 10.1016/J.Bone.2014.03.052  0.348
2014 Heine G, Drozdenko G, Grün JR, Chang HD, Radbruch A, Worm M. Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts. European Journal of Immunology. 44: 1615-21. PMID 24643722 DOI: 10.1002/Eji.201343822  0.398
2014 Westendorf K, Okhrimenko A, Grün JR, Schliemann H, Chang HD, Dong J, Radbruch A. Unbiased transcriptomes of resting human CD4⁺ CD45RO⁺ T lymphocytes. European Journal of Immunology. 44: 1866-9. PMID 24609896 DOI: 10.1002/Eji.201344323  0.399
2014 Cossarizza A, Radbruch A. Cytometry for immunology: the marriage continues. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 13-4. PMID 24591113 DOI: 10.1002/Cyto.A.22429  0.404
2014 Taddeo A, Alexander T, Khodadadi L, Cheng Q, Radbruch A, Hiepe F, Hoyer BF. A8.35 Long-lived plasma cell dynamics in autoimmunity: from the homeostasis of the immunological memory to new therapeutic challenges Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.209  0.4
2014 Kyogoku C, Smiljanovic B, Grün JR, Schulte-Wrede U, Alexander T, Biesen R, Hiepe F, Häupl T, Radbruch A, Grützkau A. A8.16 T helper lymphocytes and monocytes as biosensors of type I interferon responses in viral infection and autoimmunity Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.190  0.411
2014 Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, Roth Pv, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery M, Serra A, ... ... Radbruch A, et al. A8.10 Human memory t cells from the bone marrow are resting and maintain long-lasting memory Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.184  0.417
2014 Alexander T, Cheng Q, Klotsche J, Hoyer B, Taddeo A, Waka A, Kühl AA, Burmester G, Radbruch A, Hiepe F. A3.26 Proteasome inhibition with bortezomib in refractory SLE inhibits type I interferon and depletes plasma cells but does not inhibit their regeneration Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.119  0.383
2013 Kyogoku C, Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Häupl T, Hiepe F, Alexander T, Radbruch A, Grützkau A. Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference? Plos One. 8: e83776. PMID 24391825 DOI: 10.1136/Annrheumdis-2013-203215.6  0.394
2013 Cheng Q, Mumtaz IM, Khodadadi L, Radbruch A, Hoyer BF, Hiepe F. Autoantibodies from long-lived 'memory' plasma cells of NZB/W mice drive immune complex nephritis. Annals of the Rheumatic Diseases. 72: 2011-7. PMID 24114925 DOI: 10.1136/Annrheumdis-2013-203455  0.383
2013 Hanazawa A, Hayashizaki K, Shinoda K, Yagita H, Okumura K, Löhning M, Hara T, Tani-ichi S, Ikuta K, Eckes B, Radbruch A, Tokoyoda K, Nakayama T. CD49b-dependent establishment of T helper cell memory. Immunology and Cell Biology. 91: 524-31. PMID 23897120 DOI: 10.1038/Icb.2013.36  0.422
2013 Hanazawa A, Löhning M, Radbruch A, Tokoyoda K. CD49b/CD69-Dependent Generation of Resting T Helper Cell Memory. Frontiers in Immunology. 4: 183. PMID 23847623 DOI: 10.3389/Fimmu.2013.00183  0.44
2013 Gaber T, Tran CL, Schellmann S, Hahne M, Strehl C, Hoff P, Radbruch A, Burmester GR, Buttgereit F. Pathophysiological hypoxia affects the redox state and IL-2 signalling of human CD4+ T cells and concomitantly impairs survival and proliferation. European Journal of Immunology. 43: 1588-97. PMID 23519896 DOI: 10.1002/Eji.201242754  0.427
2013 Alexander T, Schneider S, Hoyer B, Cheng Q, Thiel A, Ziemer S, Burmester GR, Arnold R, Radbruch A, Hiepe F. Development and resolution of secondary autoimmunity after autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: competition of plasma cells for survival niches? Annals of the Rheumatic Diseases. 72: 1102-4. PMID 23361083 DOI: 10.1136/Annrheumdis-2012-202729  0.406
2013 Alexander T, Sattler A, Templin L, Kohler S, Groß C, Meisel A, Sawitzki B, Burmester GR, Arnold R, Radbruch A, Thiel A, Hiepe F. Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus. Annals of the Rheumatic Diseases. 72: 1549-58. PMID 23264341 DOI: 10.1136/Annrheumdis-2012-202216  0.435
2013 Dong J, Chang HD, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, ... Radbruch A, et al. Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-γ memory in human CD4(+) T lymphocytes. European Journal of Immunology. 43: 793-804. PMID 23255246 DOI: 10.1002/Eji.201242858  0.416
2013 Chang H-, Zehentmeier S, Hanazawa A, Sercan ö, Hauser A, Tokoyoda K, Radbruch A. FRI0035 Bone marrow stroma cells as organizers of immunological memory Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-Eular.1163  0.416
2013 Smiljanovic B, Stuhlmüller B, Maslinski W, Burmester G, Radbruch A, Grützkau A, Häupl T. A10.6 Dissecting Disease-Specific Differences in RA and OA by Transcriptome Analyses of Synovial Tissue, Blood and Bone Marrow Monocytes Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203224.6  0.317
2013 Sörensen T, Schulte-Wrede U, Pade S, Hirseland H, Burmester G, Radbruch A, Grützkau A, Häupl T. A10.4 Automated and Standardised Analysis for High Dimensional Cytometric Data Provides New Options for Complex Cell-Associated Biomarker Screening Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203224.4  0.357
2013 Schulte-Wrede U, Rosche B, Grün JR, Radbruch A, Grützkau A. A10.13 Identification of Immunophenotypic Signatures in Peripheral Blood of Multiple Sclerosis Patients by Multiparametric Flow Cytometry Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203224.13  0.415
2013 Schmid J, Porstner M, Brandl A, Roth E, Winkler T, Bösl M, Radbruch A, Wittmann J, Jäck H. A5.15 How Micrornas Control Plasma Cells Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203219.15  0.367
2013 Alexander T, Haftmann C, Templin L, Humrich J, Burmester G, Radbruch A, Hiepe F, Mashreghi M. A3.22 Upregulated microRNA-182 Expression is Associated with Enhanced Conventional CD4+ T Cell Proliferation in SLE Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203216.22  0.42
2013 Haftmann C, Stittrich A, Hradlikova K, Fang Z, Bardua M, Westendorf K, Heinz GA, Häupl T, Sieper J, Chang H, Rajewsky N, Jäck H, Radbruch A, Mashreghi M. A3.19 The miR-148a is Induced by TWIST1 and TBET and Promotes the Survival of Effector Memory T Helper 1 Lymphocytes by Regulating the Proapoptotic Gene BIM Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203216.19  0.357
2013 Kyogoku C, Grün J, Biesen R, Alexander T, Häupl T, Hiepe F, Radbruch A, Grützkau A. AB0198 Defining CD4+ T cell- and monocyte-specific interferon signatures in active, inactive and autologous stem cell transplanted lupus patients by global gene expression profiling Annals of the Rheumatic Diseases. 71: 648-648. DOI: 10.1136/Annrheumdis-2012-Eular.198  0.435
2013 Mei HE, Wirries I, Giesecke C, Frölich D, Brisslert M, Schmidt S, Engelmann R, Perka C, Radbruch A, Dörner T. OP0139 A distinct subset of CD19-negative plasma cells resides in the human bone marrow Annals of the Rheumatic Diseases. 71: 100-100. DOI: 10.1136/Annrheumdis-2012-Eular.1822  0.371
2012 Cossarizza A, Nolan J, Radbruch A, Tárnok A. Advancing cytometry for immunology. European Journal of Immunology. 42: 3106-9. PMID 23255006 DOI: 10.1002/Eji.201270100  0.344
2012 Frischbutter S, Schultheis K, Pätzel M, Radbruch A, Baumgrass R. Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 1005-11. PMID 22997026 DOI: 10.1002/Cyto.A.22204  0.318
2012 Bendfeldt H, Benary M, Scheel T, Steinbrink K, Radbruch A, Herzel H, Baumgrass R. IL-2 Expression in Activated Human Memory FOXP3(+) Cells Critically Depends on the Cellular Levels of FOXP3 as Well as of Four Transcription Factors of  T Cell Activation. Frontiers in Immunology. 3: 264. PMID 22969764 DOI: 10.3389/Fimmu.2012.00264  0.436
2012 Mumtaz IM, Hoyer BF, Panne D, Moser K, Winter O, Cheng QY, Yoshida T, Burmester GR, Radbruch A, Manz RA, Hiepe F. Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: implications for the treatment of autoimmunity. Journal of Autoimmunity. 39: 180-8. PMID 22727274 DOI: 10.1016/J.Jaut.2012.05.010  0.398
2012 Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A. The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines. Journal of Molecular Medicine (Berlin, Germany). 90: 1295-309. PMID 22610275 DOI: 10.1007/S00109-012-0907-Y  0.315
2012 Shinoda K, Tokoyoda K, Hanazawa A, Hayashizaki K, Zehentmeier S, Hosokawa H, Iwamura C, Koseki H, Tumes DJ, Radbruch A, Nakayama T. Type II membrane protein CD69 regulates the formation of resting T-helper memory. Proceedings of the National Academy of Sciences of the United States of America. 109: 7409-14. PMID 22474373 DOI: 10.1073/Pnas.1118539109  0.402
2012 Bendfeldt H, Benary M, Scheel T, Frischbutter S, Abajyan A, Radbruch A, Herzel H, Baumgrass R. Stable IL-2 decision making by endogenous c-Fos amounts in peripheral memory T-helper cells. The Journal of Biological Chemistry. 287: 18386-97. PMID 22474330 DOI: 10.1074/Jbc.M112.358853  0.402
2012 Tokoyoda K, Radbruch A. Signals controlling rest and reactivation of T helper memory lymphocytes in bone marrow. Cellular and Molecular Life Sciences : Cmls. 69: 1609-13. PMID 22460581 DOI: 10.1007/S00018-012-0969-6  0.353
2012 Haftmann C, Stittrich AB, Sgouroudis E, Matz M, Chang HD, Radbruch A, Mashreghi MF. Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs. Annals of the New York Academy of Sciences. 1247: 46-55. PMID 22236474 DOI: 10.1111/J.1749-6632.2011.06264.X  0.304
2012 Hoyer BF, Mumtaz IM, Loddenkemper K, Bruns A, Sengler C, Hermann KG, Maza S, Keitzer R, Burmester GR, Buttgereit F, Radbruch A, Hiepe F. Takayasu arteritis is characterised by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab. Annals of the Rheumatic Diseases. 71: 75-9. PMID 21953334 DOI: 10.1136/Ard.2011.153007  0.404
2012 Serra A, Könnecke I, Schmidt-Bleek K, Schell H, Radbruch A, Duda G. Lymphocytes control bone fracture healing by programming the mineralisation capacity of migratory osteogenic precursors Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201237.6  0.304
2012 Kyogoku C, Grün J, Biesen R, Alexander T, Hiepe F, Radbruch A, Grützkau A. Defining T helper (CD4) cell-specific disease signatures in active, inactive and autologous stem cell transplanted lupus patients by global gene expression profiling Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201236.2  0.392
2012 Alexander T, Templin L, Kohler S, Groß C, Sattler A, Meisel A, Burmester G, Radbruch A, Thiel A, Hiepe F. Helios+ FoxP3+ naturally occurring regulatory T cells are peripherally expanded in active systemic lupus erythematosus Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201234.23  0.451
2012 Haftmann C, Stittrich A, Heinz G, Fang Z, Rajewsky N, Chang H, Radbruch A, Mashreghi M. Regulation of pathogenic effector/memory T helper 1 lymphocyte survival by microRNA Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201234.18  0.377
2012 Smiljanovic B, Grün JR, Hiepe F, Burmester G, Radbruch A, Häupl T, Grützkau A. Monocytes transcriptom from sle and ra patients revelaed the disease-specific imprint of TNFα, IFNα and IFNγ Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201230.5  0.306
2011 Appel H, Wu P, Scheer R, Kedor C, Sawitzki B, Thiel A, Radbruch A, Sieper J, Syrbe U. Synovial and peripheral blood CD4+FoxP3+ T cells in spondyloarthritis Journal of Rheumatology. 38: 2445-2451. PMID 21921098 DOI: 10.3899/Jrheum.110377  0.393
2011 Heine G, Sims GP, Worm M, Lipsky PE, Radbruch A. Isolation of human B cell populations. Current Protocols in Immunology. Unit7.5. PMID 21809320 DOI: 10.1002/0471142735.Im0705S94  0.425
2011 Muul LM, Heine G, Silvin C, James SP, Candotti F, Radbruch A, Worm M. Measurement of proliferative responses of cultured lymphocytes. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit7.10. PMID 21809319 DOI: 10.1002/0471142735.Im0710S94  0.394
2011 Appel H, Maier R, Wu P, Scheer R, Hempfing A, Kayser R, Thiel A, Radbruch A, Loddenkemper C, Sieper J. Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response Arthritis Research and Therapy. 13. PMID 21689402 DOI: 10.1186/Ar3370  0.396
2011 Frischbutter S, Gabriel C, Bendfeldt H, Radbruch A, Baumgrass R. Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells. European Journal of Immunology. 41: 2349-57. PMID 21674474 DOI: 10.1002/Eji.201041052  0.365
2011 Geldmeyer-Hilt K, Heine G, Hartmann B, Baumgrass R, Radbruch A, Worm M. 1,25-dihydroxyvitamin D3 impairs NF-κB activation in human naïve B cells. Biochemical and Biophysical Research Communications. 407: 699-702. PMID 21420936 DOI: 10.1016/J.Bbrc.2011.03.078  0.356
2011 Chang H, Radbruch A. Targeting pathogenic T helper cell memory Annals of the Rheumatic Diseases. 70. PMID 21339226 DOI: 10.1136/Ard.2010.140954  0.39
2011 Hiepe F, Dörner T, Hauser AE, Hoyer BF, Mei H, Radbruch A. Long-lived autoreactive plasma cells drive persistent autoimmune inflammation Nature Reviews Rheumatology. 7: 170-178. PMID 21283146 DOI: 10.1038/Nrrheum.2011.1  0.41
2011 Hartmann B, Heine G, Babina M, Steinmeyer A, Zügel U, Radbruch A, Worm M. Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response Allergy. 66: 540-548. PMID 21121929 DOI: 10.1111/J.1398-9995.2010.02513.X  0.369
2011 Radbruch A. Cytokine imprinting - mechanisms for memory Arthritis Research & Therapy. 13: 1-7. DOI: 10.1186/Ar3416  0.428
2011 Hiepe F, Hoyer B, Alexander T, Taddeo A, Voll R, Radbruch A. Therapeutic inhibition of proteasomes in systemic lupus erythematosus Journal of Translational Medicine. 9: 1-2. DOI: 10.1186/1479-5876-9-S2-I9  0.427
2011 Schulte-Wrede U, Steinbrich-Zöllner M, Grün JR, Sieper J, Radbruch A, Grützkau A. Anti-TNF-α therapy monitoring in chronic rheumatic diseases by cytometric profiling of peripheral blood cells Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.149021.12  0.313
2011 Mei H, Frölich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony H, Radbruch A, Dörner T. Steady state generation of mucosal IgA+ plasmablasts is not abrogated by B cell depletion therapy with rituximab Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.149005.19  0.447
2011 Stittrich A, Haftmann C, Sgouroudis E, Fang Z, Rajewsky N, Chang H, Radbruch A, Mashreghi M. Inhibition of miR-182 decreases OVA-induced arthritis in mice Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148981.3  0.371
2011 Albrecht I, Hradilkova K, Westendorf K, Weber M, Radbruch A, Chang H. Twist1 and Hopx determine function and persistence of pathogenic memory/effector T cells Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148981.25  0.473
2011 Alexander T, Templin L, Kohler S, Groβ C, Sattler A, Meisel A, Perka C, Burmester G, Arnold R, Radbruch A, Thiel A, Hiepe F. Increased levels of circulating Helios + FoxP3 + natural regulatory T cells in systemic lupus erythematosus Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148981.19  0.385
2011 Häupl T, Biesen R, Smiljanovic B, Grün JR, Weix J, Stuhlmüller B, Villiger PM, Burmester G, Radbruch A, Grützkau A. The type 1 interferon signature: facts, fads and fallacies Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148965.26  0.337
2011 Thomas S, Metzke D, Schmitz J, Dörffel Y, Radbruch A, Baumgart D. Anti-inflammatory effects of Saccharomyces boulardii mediated by myeloid dendritic cells from patients with Crohn's disease and ulcerative colitis Zeitschrift Fur Gastroenterologie. 49: 101. DOI: 10.1055/S-0031-1285373  0.301
2010 Lexberg MH, Taubner A, Albrecht I, Lepenies I, Richter A, Kamradt T, Radbruch A, Chang H. IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. European Journal of Immunology. 40: 3017-3027. PMID 21061434 DOI: 10.1002/Eji.201040539  0.393
2010 Albrecht I, Niesner U, Janke M, Menning A, Loddenkemper C, Kühl AA, Lepenies I, Lexberg MH, Westendorf K, Hradilkova K, Grün J, Hamann A, Epstein JA, Chang HD, Tokoyoda K, ... Radbruch A, et al. Persistence of effector memory Th1 cells is regulated by Hopx. European Journal of Immunology. 40: 2993-3006. PMID 21061432 DOI: 10.1002/Eji.201040936  0.427
2010 Stittrich AB, Haftmann C, Sgouroudis E, Kühl AA, Hegazy AN, Panse I, Riedel R, Flossdorf M, Dong J, Fuhrmann F, Heinz GA, Fang Z, Li N, Bissels U, Hatam F, ... ... Radbruch A, et al. The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nature Immunology. 11: 1057-62. PMID 20935646 DOI: 10.1038/Ni.1945  0.358
2010 Mei HE, Frölich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony H, Radbruch A, Dörner T. Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab. Blood. 116: 5181-5190. PMID 20829370 DOI: 10.1182/Blood-2010-01-266536  0.438
2010 Yoshida T, Mei H, Dörner T, Hiepe F, Radbruch A, Fillatreau S, Hoyer BF. Memory B and memory plasma cells. Immunological Reviews. 237: 117-139. PMID 20727033 DOI: 10.1111/J.1600-065X.2010.00938.X  0.384
2010 Smiljanovic B, Grün JR, Steinbrich-Zöllner M, Stuhlmüller B, Häupl T, Burmester GR, Radbruch A, Grützkau A, Baumgrass R. Defining TNF-α- and LPS-induced gene signatures in monocytes to unravel the complexity of peripheral blood transcriptomes in health and disease Journal of Molecular Medicine. 88: 1065-1079. PMID 20640394 DOI: 10.1007/S00109-010-0648-8  0.327
2010 Grützkau A, Radbruch A. Small but mighty: How the MACS®-technology based on nanosized superparamagnetic particles has helped to analyze the immune system within the last 20 years Cytometry Part A. 77: 643-647. PMID 20583279 DOI: 10.1002/Cyto.A.20918  0.351
2010 Brandt C, Liman P, Bendfeldt H, Mueller K, Reinke P, Radbruch A, Worm M, Baumgrass R. Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 607-13. PMID 20583270 DOI: 10.1002/Cyto.A.20928  0.382
2010 Hoff H, Kolar P, Ambach A, Radbruch A, Brunner-Weinzierl MC. CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch. Molecular Immunology. 47: 1875-81. PMID 20417562 DOI: 10.1016/J.Molimm.2010.03.017  0.4
2010 Mariani L, Schulz EG, Lexberg MH, Helmstetter C, Radbruch A, Löhning M, Höfer T. Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression. Molecular Systems Biology. 6: 359. PMID 20393579 DOI: 10.1038/Msb.2010.13  0.417
2010 Spies CM, Gaber T, Hahne M, Naumann L, Tripmacher R, Schellmann S, Stahn C, Burmester G, Radbruch A, Buttgereit F. Rimexolone inhibits proliferation, cytokine expression and signal transduction of human CD4+ T-cells. Immunology Letters. 131: 24-32. PMID 20363256 DOI: 10.1016/J.Imlet.2010.03.009  0.424
2010 Enghard P, Humrich JY, Chu VT, Grussie E, Hiepe F, Burmester GR, Radbruch A, Berek C, Riemekasten G. Class switching and consecutive loss of dsDNA-reactive B1a B cells from the peritoneal cavity during murine lupus development. European Journal of Immunology. 40: 1809-18. PMID 20333624 DOI: 10.1002/Eji.200940050  0.405
2010 Luger EO, Wegmann M, Achatz G, Worm M, Renz H, Radbruch A. Allergy for a lifetime? Allergology International : Official Journal of the Japanese Society of Allergology. 59: 1-8. PMID 20186004 DOI: 10.2332/Allergolint.10-Rai-0175  0.409
2010 Tokoyoda K, Hauser AE, Nakayama T, Radbruch A. Organization of immunological memory by bone marrow stroma Nature Reviews Immunology. 10: 193-200. PMID 20154734 DOI: 10.1038/Nri2727  0.317
2010 Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, et al. Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nature Medicine. 16: 339-45. PMID 20139992 DOI: 10.1038/Nm.2104  0.35
2010 Hegazy AN, Peine M, Helmstetter C, Panse I, Fröhlich A, Bergthaler A, Flatz L, Pinschewer DD, Radbruch A, Löhning M. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity. 32: 116-28. PMID 20079668 DOI: 10.1016/J.Immuni.2009.12.004  0.431
2010 Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, Geelen CMMv, Lukens MV, Bleek GMv, Widjojoatmodjo MN, Bogers WMJM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T. Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming Nature Medicine. 16: 123-128. PMID 20023635 DOI: 10.1038/Nm.2071  0.409
2010 Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G. Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. Proceedings of the National Academy of Sciences of the United States of America. 107: 204-9. PMID 20018660 DOI: 10.1073/Pnas.0903158107  0.395
2010 Gerl V, Lischka A, Panne D, Grossmann P, Berthold R, Hoyer BF, Biesen R, Bruns A, Alexander T, Jacobi A, Dörner T, Burmester GR, Radbruch A, Hiepe F. Blood dendritic cells in systemic lupus erythematosus exhibit altered activation state and chemokine receptor function. Annals of the Rheumatic Diseases. 69: 1370-7. PMID 19854711 DOI: 10.1136/Ard.2009.111021  0.306
2010 Wagner B, Siebenkotten G, Leibold W, Radbruch A. Expression of a 4-(hydroxy-3-nitro-phenyl) acetyl (NP) specific equi-murine IgE antibody that mediates histamine release in vitro and a type I skin reaction in vivo. Equine Veterinary Journal. 34: 657-665. PMID 12455835 DOI: 10.2746/042516402776250324  0.357
2010 Deenick E, Chan A, Ma CS, Brink R, Tangye S, Tokoyoda K, Shinoda K, Hanazawa A, Zehentmeier S, Fukasawa T, Radbruch A, Nakayama T, Thomas PG, Reynolds C, Handel A, et al. T cell homeostasis and memory (WS-059) Chairpersons: Masaaki Murakami, Naoto Ishii International Immunology. 22. DOI: 10.1093/Intimm/Dxq407  0.362
2010 Mohr E, Cunningham AF, Toellner KM, Manz RA, Bobat S, Coughlan R, MacLennan ICM, Serre K, Fooksman DR, Skokos D, Dustin ML, Nussenzweig M, Nutt SL, Hasbold J, Emslie D, ... ... Radbruch A, et al. Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt International Immunology. 22. DOI: 10.1093/Intimm/Dxq314  0.335
2010 Ahmed R, Bevan MJ, Feau S, Wolkers M, Borst J, Schumacher T, Yagita H, Schoenberger S, Sallusto F, Radbruch A, Hauser A, Tokoyoda K, Shlomchik M, Good-Jacobson K, Khalil A. T and B cell memory (SY3-4) Chairpersons: Toshitada Takemori, Federica Sallusto International Immunology. 22. DOI: 10.1093/Intimm/Dxq287  0.374
2010 Lexberg M, Taubner A, Albrecht I, Richter A, Kamradt T, Radbruch A, Chang H. IFN-γ and IL-12 Synergize to Convert in vivo Generated Th17 into Th1/17 Lineage Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.397  0.347
2010 Mashreghi M, Stittrich A, Haftmann C, Hegazy A, Löhning M, Chang H, Radbruch A. MicroRNA-182 Regulates Expansion of Activated T Helper Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.080  0.379
2009 Luger EO, Fokuhl V, Wegmann M, Abram M, Tillack K, Achatz G, Manz RA, Worm M, Radbruch A, Renz H. Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge. The Journal of Allergy and Clinical Immunology. 124: 819-26.e4. PMID 19815119 DOI: 10.1016/J.Jaci.2009.06.047  0.388
2009 Baumgart DC, Thomas S, Przesdzing I, Metzke D, Bielecki C, Lehmann SM, Lehnardt S, Dörffel Y, Sturm A, Scheffold A, Schmitz J, Radbruch A. Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease. Clinical and Experimental Immunology. 157: 423-36. PMID 19664152 DOI: 10.1111/J.1365-2249.2009.03981.X  0.348
2009 Tokoyoda K, Zehentmeier S, Chang H, Radbruch A. Organization and maintenance of immunological memory by stroma niches. European Journal of Immunology. 39: 2095-2099. PMID 19637201 DOI: 10.1002/Eji.200939500  0.34
2009 Dörner T, Radbruch A, Burmester GR. B-cell-directed therapies for autoimmune disease Nature Reviews Rheumatology. 5: 433-441. PMID 19581902 DOI: 10.1038/Nrrheum.2009.141  0.38
2009 Kuhne M, Erben U, Schulze-Tanzil G, Köhler D, Wu P, Richter FJ, John T, Radbruch A, Sieper J, Appel H. HLA-B27-restricted antigen presentation by human chondrocytes to CD8+ T cells: potential contribution to local immunopathologic processes in ankylosing spondylitis. Arthritis and Rheumatism. 60: 1635-46. PMID 19479861 DOI: 10.1002/Art.24549  0.432
2009 Brandt C, Pavlovic V, Radbruch A, Worm M, Baumgrass R. Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis. Allergy. 64: 1588-1596. PMID 19432936 DOI: 10.1111/J.1398-9995.2009.02054.X  0.411
2009 Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grün JR, Löhning M, Radbruch A. Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow. Immunity. 30: 721-730. PMID 19427242 DOI: 10.1016/J.Immuni.2009.03.015  0.42
2009 Schulz EG, Mariani L, Radbruch A, Höfer T. Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12 Immunity. 30: 673-683. PMID 19409816 DOI: 10.1016/J.Immuni.2009.03.013  0.397
2009 Abram M, Wegmann M, Fokuhl V, Sonar S, Luger EO, Kerzel S, Radbruch A, Renz H, Zemlin M. Nerve growth factor and neurotrophin-3 mediate survival of pulmonary plasma cells during the allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 182: 4705-12. PMID 19342646 DOI: 10.4049/Jimmunol.0802814  0.341
2009 Thomas S, Przesdzing I, Metzke D, Schmitz J, Radbruch A, Baumgart DC. Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation. Clinical and Experimental Immunology. 156: 78-87. PMID 19161443 DOI: 10.1111/J.1365-2249.2009.03878.X  0.408
2009 Mei HE, Yoshida T, Sime W, Hiepe F, Thiele K, Manz RA, Radbruch A, Dörner T. Blood-borne human plasma cells in steady state are derived from mucosal immune responses Blood. 113: 2461-2469. PMID 18987362 DOI: 10.1182/Blood-2008-04-153544  0.393
2009 Martinez-Gamboa L, Mei H, Loddenkemper C, Ballmer B, Hansen A, Lipsky PE, Emmerich F, Radbruch A, Salama A, Dörner T. Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura. Clinical Immunology. 130: 199-212. PMID 18977183 DOI: 10.1016/J.Clim.2008.09.009  0.409
2009 Alexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F. Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood. 113: 214-23. PMID 18824594 DOI: 10.1182/Blood-2008-07-168286  0.424
2009 Chang H, Albrecht I, Niesner U, Radbruch A. T.123. Targeting the Pathogenic Immunological Memory in Chronic Autoimmune Inflammation Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.256  0.308
2008 Albrecht I, Niesner U, Janke M, Radbruch A, Chang H. Das Entzündungsgedächtnis des Immunsystems Zeitschrift Fur Rheumatologie. 67: 684-688. PMID 19002471 DOI: 10.1007/S00393-008-0403-5  0.418
2008 Lexberg MH, Taubner A, Förster A, Albrecht I, Richter A, Kamradt T, Radbruch A, Chang H. Th memory for interleukin-17 expression is stable in vivo. European Journal of Immunology. 38: 2654-2664. PMID 18825747 DOI: 10.1002/Eji.200838541  0.372
2008 Häupl T, ØStensen M, Grützkau A, Radbruch A, Burmester G, Villiger PM. Reactivation of rheumatoid arthritis after pregnancy: increased phagocyte and recurring lymphocyte gene activity. Arthritis & Rheumatism. 58: 2981-2992. PMID 18821679 DOI: 10.1002/Art.23907  0.339
2008 Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, ... ... Radbruch A, et al. Autoregulation of Th1-mediated inflammation by twist1 Journal of Experimental Medicine. 205: 1889-1901. PMID 18663125 DOI: 10.1084/Jem.20072468  0.435
2008 Heine G, Niesner U, Chang H, Steinmeyer A, Zügel U, Zuberbier T, Radbruch A, Worm M. 1,25-dihydroxyvitamin D(3) promotes IL-10 production in human B cells. European Journal of Immunology. 38: 2210-2218. PMID 18651709 DOI: 10.1002/Eji.200838216  0.401
2008 Jacobi AM, Reiter K, Mackay M, Aranow C, Hiepe F, Radbruch A, Hansen A, Burmester GR, Diamond B, Lipsky PE, Dörner T. Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95. Arthritis and Rheumatism. 58: 1762-73. PMID 18512812 DOI: 10.1002/Art.23498  0.422
2008 Tripmacher R, Gaber T, Dziurla R, Häupl T, Erekul K, Grützkau A, Tschirschmann M, Scheffold A, Radbruch A, Burmester G, Buttgereit F. Human CD4+ T cells maintain specific functions even under conditions of extremely restricted ATP production European Journal of Immunology. 38: 1631-1642. PMID 18493983 DOI: 10.1002/Eji.200738047  0.377
2008 Tarlinton D, Radbruch A, Hiepe F, Dörner T. Plasma cell differentiation and survival Current Opinion in Immunology. 20: 162-169. PMID 18456483 DOI: 10.1016/J.Coi.2008.03.016  0.421
2008 Lalla CD, Festuccia N, Albrecht I, Chang HD, Andolfi G, Benninghoff U, Bombelli F, Borsellino G, Aiuti A, Radbruch A, Dellabona P, Casorati G. Innate-like effector differentiation of human invariant NKT cells driven by IL-7. Journal of Immunology. 180: 4415-4424. PMID 18354162 DOI: 10.4049/Jimmunol.180.7.4415  0.433
2008 Steinbrich-Zöllner M, Grün JR, Kaiser T, Biesen R, Raba K, Wu P, Thiel A, Rudwaleit M, Sieper J, Burmester G, Radbruch A, Grützkau A. From transcriptome to cytome: integrating cytometric profiling, multivariate cluster, and prediction analyses for a phenotypical classification of inflammatory diseases. Cytometry Part A. 73: 333-340. PMID 18307258 DOI: 10.1002/Cyto.A.20505  0.359
2008 Thiel A, Alexander T, Schmidt CA, Przybylski GK, Kimmig S, Kohler S, Radtke H, Gromnica-Ihle E, Massenkeil G, Radbruch A, Arnold R, Hiepe F. Direct assessment of thymic reactivation after autologous stem cell transplantation. Acta Haematologica. 119: 22-7. PMID 18292651 DOI: 10.1159/000117824  0.415
2008 Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. The Journal of Experimental Medicine. 205: 53-61. PMID 18195073 DOI: 10.1084/Jem.20071855  0.458
2008 Jacobi AM, Goldenberg DM, Hiepe F, Radbruch A, Burmester GR, Dörner T. Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls Annals of the Rheumatic Diseases. 67: 450-457. PMID 17673490 DOI: 10.1136/Ard.2007.075762  0.417
2007 Chang H, Radbruch A. The pro- and anti-inflammatory potential of IL-12: the dual role of Th1 cells Expert Review of Clinical Immunology. 3: 709-719. PMID 20477022 DOI: 10.1586/1744666X.3.5.709  0.448
2007 Mei HE, Yoshida T, Muehlinghaus G, Hiepe F, Dörner T, Radbruch A, Hoyer BF. Phenotypic analysis of B-cells and plasma cells. Methods in Molecular Medicine. 136: 3-18. PMID 17983136 DOI: 10.1007/978-1-59745-402-5_1  0.429
2007 Podtschaske M, Benary U, Zwinger S, Höfer T, Radbruch A, Baumgrass R. Digital NFATc2 Activation per Cell Transforms Graded T Cell Receptor Activation into an All-or-None IL-2 Expression Plos One. 2. PMID 17895976 DOI: 10.1371/Journal.Pone.0000935  0.437
2007 Dörner T, Radbruch A. Antibodies and B Cell Memory in Viral Immunity Immunity. 27: 384-392. PMID 17892847 DOI: 10.1016/J.Immuni.2007.09.002  0.39
2007 Chang HD, Radbruch A. The pro- and anti-inflammatory potential of interleukin-12. Annals of the New York Academy of Sciences. 1109: 40-6. PMID 17785289 DOI: 10.1196/annals.1398.006  0.302
2007 Sieber M, Karanik M, Brandt C, Blex C, Podtschaske M, Erdmann F, Rost R, Serfling E, Liebscher J, Pätzel M, Radbruch A, Fischer G, Baumgrass R. Inhibition of calcineurin-NFAT signaling by the pyrazolopyrimidine compound NCI3. European Journal of Immunology. 37: 2617-2626. PMID 17694572 DOI: 10.1002/Eji.200737087  0.328
2007 Dong J, Ivascu C, Chang H, Wu P, Angeli R, Maggi L, Eckhardt F, Tykocinski L, Haefliger C, Möwes B, Sieper J, Radbruch A, Annunziato F, Thiel A. IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes. Journal of Immunology. 179: 2389-2396. PMID 17675500 DOI: 10.4049/Jimmunol.179.4.2389  0.396
2007 Chang H, Helbig C, Tykocinski L, Kreher S, Koeck J, Niesner U, Radbruch A. Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3. European Journal of Immunology. 37: 807-817. PMID 17304625 DOI: 10.1002/Eji.200636385  0.342
2006 Thiel A, Wu P, Lanowska M, Dong J, Radbruch A, Sieper J. Identification of immunodominant CD4+ T cell epitopes in patients with Yersinia-induced reactive arthritis by cytometric cytokine secretion assay. Arthritis & Rheumatism. 54: 3583-3590. PMID 17075864 DOI: 10.1002/Art.22183  0.431
2006 Hebel K, Griewank K, Inamine A, Chang HD, Müller-Hilke B, Fillatreau S, Manz RA, Radbruch A, Jung S. Plasma cell differentiation in T-independent type 2 immune responses is independent of CD11c(high) dendritic cells. European Journal of Immunology. 36: 2912-9. PMID 17051619 DOI: 10.1002/Eji.200636356  0.601
2006 Radbruch A, Muehlinghaus G, Luger EO, Inamine A, Smith KGC, Dörner T, Hiepe F. Competence and competition: the challenge of becoming a long-lived plasma cell. Nature Reviews Immunology. 6: 741-750. PMID 16977339 DOI: 10.1038/Nri1886  0.386
2006 Höfer T, Muehlinghaus G, Moser K, Yoshida T, Mei HE, Hebel K, Hauser A, Hoyer B, Luger EO, Dörner T, Manz RA, Hiepe F, Radbruch A. Adaptation of humoral memory. Immunological Reviews. 211: 295-302. PMID 16824136 DOI: 10.1111/J.0105-2896.2006.00380.X  0.385
2006 Fillatreau S, Radbruch A. IRF4 - a factor for class switching and antibody secretion. Nature Immunology. 7: 704-706. PMID 16785887 DOI: 10.1038/Ni0706-704  0.401
2006 Manz RA, Moser K, Burmester GR, Radbruch A, Hiepe F. Immunological Memory Stabilizing Autoreactivity Current Topics in Microbiology and Immunology. 305: 241-257. PMID 16724809 DOI: 10.1007/3-540-29714-6_12  0.44
2006 Hiepe F, Radbruch A. Is long-term humoral immunity in the mucosa provided by long-lived plasma cells? A question still open. European Journal of Immunology. 36: 1068-1069. PMID 16639706 DOI: 10.1002/Eji.200636118  0.359
2006 Moser K, Tokoyoda K, Radbruch A, MacLennan I, Manz RA. Stromal niches, plasma cell differentiation and survival Current Opinion in Immunology. 18: 265-270. PMID 16616478 DOI: 10.1016/J.Coi.2006.03.004  0.398
2006 Spies CM, Schaumann DHS, Berki T, Mayer K, Jakstadt M, Huscher D, Wunder C, Burmester G, Radbruch A, Lauster R, Scheffold A, Buttgereit F. Membrane glucocorticoid receptors are down regulated by glucocorticoids in patients with systemic lupus erythematosus and use a caveolin-1-independent expression pathway Annals of the Rheumatic Diseases. 65: 1139-1146. PMID 16449313 DOI: 10.1136/Ard.2005.048272  0.383
2006 Moser K, Muehlinghaus G, Manz R, Mei H, Voigt C, Yoshida T, Dörner T, Hiepe F, Radbruch A. Long-lived plasma cells in immunity and immunopathology. Immunology Letters. 103: 83-85. PMID 16280169 DOI: 10.1016/J.Imlet.2005.09.009  0.403
2006 Arbach O, Frentsch M, Chmielewicz B, Kaiser M, Ellerbrock H, Lauster R, Arnold R, Radbruch A, Voigt S, Ebell W, Thiel A. Treatment of Adenovirus Infection by Adoptive Immunotherapy: Adenovirus Capsid Hexon Is the Main Target Protein of Adenovirus-Specific Cellular Immunity. Blood. 108: 2930-2930. DOI: 10.1182/Blood.V108.11.2930.2930  0.422
2006 Arbach O, Frentsch M, Barbara C, Marco K, Ellerbrok H, Lauster R, Radbruch A, Scheffold A, Wolfram E, Thiel A. Su.5. Antigen-Induced Cd154 Expression As a Novel Tool for Identification of Immundominant Pathogen Target Antigens Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.432  0.33
2006 Sattler A, Wagner U, Rossol M, Sieper J, Krause A, Radbruch A, Romagnani C, Thiel A. Sa.56. IL-2 Receptor Common γ-Chain Signalling Required for Cytokine Induced Human IFNγ+ Effector Th Cells That Participate in Rheumatoid Arthritis Inflammation Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.288  0.354
2006 Chang H, Helbig C, Dong J, Rosa MDL, Brandenburg S, Niesner U, Scheffold A, Thiel A, Radbruch A. Sa.51. The Molecular Basis of Functional Stability of Regulatory T-Cells: The Memory of TH Cells for IL-10 Expression Is Conditional Unless the Gene Is Imprinted by Gata-3 Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.283  0.418
2005 Hoyer BF, Manz RA, Radbruch A, Hiepe F. Long-lived plasma cells and their contribution to autoimmunity Annals of the New York Academy of Sciences. 1050: 124-133. PMID 16014527 DOI: 10.1196/Annals.1313.014  0.408
2005 Romagnani C, Chiesa MD, Kohler S, Moewes B, Radbruch A, Moretta L, Moretta A, Thiel A. Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells. European Journal of Immunology. 35: 2452-2458. PMID 15997468 DOI: 10.1002/Eji.200526069  0.451
2005 Tykocinski LO, Hajkova P, Chang HD, Stamm T, Sözeri O, Löhning M, Hu-Li J, Niesner U, Kreher S, Friedrich B, Pannetier C, Grütz G, Walter J, Paul WE, Radbruch A. A critical control element for interleukin-4 memory expression in T helper lymphocytes. The Journal of Biological Chemistry. 280: 28177-85. PMID 15941711 DOI: 10.1074/Jbc.M502038200  0.341
2005 Manz RA, Hauser AE, Hiepe F, Radbruch A. Maintenance Of Serum Antibody Levels Annual Review of Immunology. 23: 367-386. PMID 15771575 DOI: 10.1146/Annurev.Immunol.23.021704.115723  0.383
2005 Frey O, Petrow PK, Gajda M, Siegmund K, Huehn J, Scheffold A, Hamann A, Radbruch A, Bräuer R. The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells Arthritis Research & Therapy. 7: 1-11. PMID 15743476 DOI: 10.1186/Ar1484  0.398
2005 Dörner T, Radbruch A. Selecting B cells and plasma cells to memory Journal of Experimental Medicine. 201: 497-499. PMID 15728231 DOI: 10.1084/Jem.20050218  0.393
2005 Gerl V, Hostmann B, Johnen C, Waka A, Gerl M, Schumann F, Klein R, Radbruch A, Hiepe F. The intracellular 52-kd Ro/SSA autoantigen in keratinocytes is up-regulated by tumor necrosis factor alpha via tumor necrosis factor receptor I. Arthritis and Rheumatism. 52: 531-8. PMID 15692985 DOI: 10.1002/Art.20851  0.309
2005 Muehlinghaus G, Cigliano L, Huehn S, Peddinghaus A, Leyendeckers H, Hauser AE, Hiepe F, Radbruch A, Arce S, Manz RA. Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells Blood. 105: 3965-3971. PMID 15687242 DOI: 10.1182/Blood-2004-08-2992  0.451
2005 Odendahl M, Mei H, Hoyer BF, Jacobi AM, Hansen A, Muehlinghaus G, Berek C, Hiepe F, Manz R, Radbruch A, Dörner T. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response Blood. 105: 1614-1621. PMID 15507523 DOI: 10.1182/Blood-2004-07-2507  0.409
2005 Niesner U, Albrecht I, Baumgrass R, Janitz M, Lehrach H, Haeupl T, Grun J, Burmester G, Grutzkau A, Radbruch A. Arthritis Research & Therapy. 7: P90. DOI: 10.1186/Ar1611  0.303
2005 Arbach O, Frentsch M, Voigt S, Chmielewicz B, Kaiser M, Ellerbrok H, Lauster R, Radbruch A, Scheffold A, Ebell W, Thiel A. Adenovirus Capsid Hexon Is the Main Target Protein of Adenovirus-Specific CD4+ T-Cells: Fundamentals for Targeting Adenovirus by Adoptive Immunotherapy. Blood. 106: 3034-3034. DOI: 10.1182/Blood.V106.11.3034.3034  0.421
2005 Hiepe F, Radbruch A. B cells in autoimmunity: more than antibodies? Blood. 106: 2227-2227. DOI: 10.1182/Blood-2005-07-2891  0.394
2004 Riemekasten G, Langnickel D, Enghard P, Undeutsch R, Humrich J, Ebling FM, Hocher B, Humaljoki T, Neumayer H, Burmester G, Hahn BH, Radbruch A, Hiepe F. Intravenous Injection of a D1 Protein of the Smith Proteins Postpones Murine Lupus and Induces Type 1 Regulatory T Cells Journal of Immunology. 173: 5835-5842. PMID 15494537 DOI: 10.4049/Jimmunol.173.9.5835  0.46
2004 Syrbe U, Jennrich S, Schottelius A, Richter A, Radbruch A, Hamann A. Differential regulation of P-selectin ligand expression in naive versus memory CD4+ T cells: evidence for epigenetic regulation of involved glycosyltransferase genes. Blood. 104: 3243-3248. PMID 15297307 DOI: 10.1182/Blood-2003-09-3047  0.443
2004 Mariani L, Löhning M, Radbruch A, Höfer T. Transcriptional control networks of cell differentiation: insights from helper T lymphocytes. Progress in Biophysics & Molecular Biology. 86: 45-76. PMID 15261525 DOI: 10.1016/J.Pbiomolbio.2004.02.007  0.36
2004 Hoyer BF, Moser K, Hauser AE, Peddinghaus A, Voigt C, Eilat D, Radbruch A, Hiepe F, Manz RA. Short-lived Plasmablasts and Long-lived Plasma Cells Contribute to Chronic Humoral Autoimmunity in NZB/W Mice Journal of Experimental Medicine. 199: 1577-1584. PMID 15173206 DOI: 10.1084/Jem.20040168  0.392
2004 Thiel A, Scheffold A, Radbruch A. Antigen-specific cytometry--new tools arrived! Clinical Immunology. 111: 155-161. PMID 15137948 DOI: 10.1016/J.Clim.2003.12.017  0.375
2004 Arce S, Luger E, Muehlinghaus G, Cassese G, Hauser A, Horst A, Lehnert K, Odendahl M, Hönemann D, Heller K, Kleinschmidt H, Berek C, Dörner T, Krenn V, Hiepe F, ... ... Radbruch A, et al. CD38 low IgG‐secreting cells are precursors of various CD38 high‐expressing plasma cell populations Journal of Leukocyte Biology. 75: 1022-1028. PMID 15020647 DOI: 10.1189/Jlb.0603279  0.444
2004 Pandiyan P, Gärtner D, Soezeri O, Radbruch A, Schulze-Osthoff K, Brunner-Weinzierl MC. CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function Journal of Experimental Medicine. 199: 831-842. PMID 15007096 DOI: 10.1084/Jem.20031058  0.436
2004 Skapenko A, Leipe J, Niesner U, Devriendt K, Beetz R, Radbruch A, Kalden JR, Lipsky PE, Schulze-Koops H. GATA-3 in Human T Cell Helper Type 2 Development Journal of Experimental Medicine. 199: 423-428. PMID 14757746 DOI: 10.1084/Jem.20031323  0.439
2004 Page G, Sattler A, Kersten S, Thiel A, Radbruch A, Miossec P. Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression. The American Journal of Pathology. 164: 409-17. PMID 14742247 DOI: 10.1016/S0002-9440(10)63131-8  0.453
2004 Bartholome B, Spies CM, Gaber T, Schuchmann S, Berki T, Kunkel D, Bienert M, Radbruch A, Burmester GR, Lauster R, Scheffold A, Buttgereit F. Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 70-80. PMID 14718388 DOI: 10.1096/Fj.03-0328Com  0.315
2004 Skapenko A, Leipe J, Niesner U, Devriendt K, Beetz R, Radbruch A, Kalden J, Lipsky P, Schulze-Koops H. GATA-3 in human T helper cell type 2 development Arthritis Research & Therapy. 6: 72-72. DOI: 10.1186/Ar1428  0.469
2004 Hückel M, Irmler I, Simon J, Radbruch A, Scheffold A, Bräuer R. Protective role of interferon gamma in murine antigen-induced arthritis Arthritis Research & Therapy. 6: 59-59. DOI: 10.1186/Ar1395  0.304
2004 Luger E, Achatz G, Olze H, Mecho C, Radbruch A, Berek C. Allergen specific IgG memory B cells in atopic and non-atopic individuals The Journal of Allergy and Clinical Immunology. 113. DOI: 10.1016/J.Jaci.2004.01.014  0.426
2004 Löhning M, Chang H, Tykocinski L, Niesner U, Radbruch A. Cytokine memory in chronic immune activation Autoimmunity Reviews. 3: 590. DOI: 10.1016/J.Autrev.2004.07.032  0.304
2004 Hiepe F, Manz RA, Radbruch A. The role of long-lived plasma cells in autoimmunity Autoimmunity Reviews. 3: 579-581. DOI: 10.1016/J.Autrev.2004.07.024  0.349
2003 Löhning M, Richter A, Stamm T, Hu-Li J, Assenmacher M, Paul WE, Radbruch A. Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation. Proceedings of the National Academy of Sciences of the United States of America. 100: 12307-12. PMID 14514890 DOI: 10.1073/Pnas.2035254100  0.372
2003 Cassese G, Arce S, Hauser AE, Lehnert K, Moewes B, Mostarac M, Muehlinghaus G, Szyska M, Radbruch A, Manz RA. Plasma Cell Survival Is Mediated by Synergistic Effects of Cytokines and Adhesion-Dependent Signals Journal of Immunology. 171: 1684-1690. PMID 12902466 DOI: 10.4049/Jimmunol.171.4.1684  0.4
2003 Kunkel D, Kirchhoff D, Volkmer-Engert R, Radbruch A, Scheffold A. Sensitive visualization of peptide presentation in vitro and ex vivo. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 54: 19-26. PMID 12820117 DOI: 10.1002/Cyto.A.10055  0.364
2003 Jacobi AM, Odendahl M, Reiter K, Bruns A, Burmester GR, Radbruch A, Valet G, Lipsky PE, Dörner T. Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus Arthritis and Rheumatism. 48: 1332-1342. PMID 12746906 DOI: 10.1002/Art.10949  0.392
2003 Kunkel D, Kirchhoff D, Nishikawa S, Radbruch A, Scheffold A. Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice. European Journal of Immunology. 33: 1292-301. PMID 12731054 DOI: 10.1002/Eji.200323383  0.402
2003 Lindenau S, Scholze S, Odendahl M, Dörner T, Radbruch A, Burmester G, Berek C. Aberrant activation of B cells in patients with rheumatoid arthritis. Annals of the New York Academy of Sciences. 987: 246-248. PMID 12727646 DOI: 10.1111/J.1749-6632.2003.Tb06055.X  0.334
2003 Wagner B, Radbruch A, Rohwer J, Leibold W. Monoclonal anti-equine IgE antibodies with specificity for different epitopes on the immunoglobulin heavy chain of native IgE Veterinary Immunology and Immunopathology. 92: 45-60. PMID 12628763 DOI: 10.1016/S0165-2427(03)00007-2  0.336
2003 Riemekasten G, Langnickel D, Ebling FM, Karpouzas G, Kalsi J, Herberth G, Tsao BP, Henklein P, Langer S, Burmester G, Radbruch A, Hiepe F, Hahn BH. Identification and characterization of SmD183-119-reactive T cells that provide T cell help for pathogenic anti-double-stranded DNA antibodies. Arthritis & Rheumatism. 48: 475-485. PMID 12571858 DOI: 10.1002/Art.10762  0.438
2003 Löhning M, Hutloff A, Kallinich T, Mages HW, Bonhagen K, Radbruch A, Hamelmann E, Kroczek RA. Expression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 Journal of Experimental Medicine. 197: 181-193. PMID 12538658 DOI: 10.1084/Jem.20020632  0.445
2003 Bräuer R, Frey O, Petrow P, Scheffold A, Radbruch A. Regulatory T cells in experimental arthritis Arthritis Research & Therapy. 5: 128-128. DOI: 10.1186/Ar929  0.373
2003 Tykocinski L, Hajkova P, Stamm T, Sözeri O, Löhning M, Friedrich B, Hu-Li J, Pannetier C, Paul W, Grütz G, Walter J, Radbruch A. A GATA-3 binding site in the first intron of the interleukin-4 gene defines a critical element for the memory expression of interleukin-4 in Th lymphocytes Arthritis Research & Therapy. 5: 61-61. DOI: 10.1186/Ar691  0.388
2003 Page G, Sattler A, Thiel A, Radbruch A, Miossec P. Plasma-cell like morphotype with loss of CD3 expression by Th1 cytokine producing cells Arthritis Research & Therapy. 5: 54-54. DOI: 10.1186/Ar684  0.423
2002 Schneider S, Bruns A, Moewes B, Holzknecht B, Hausdorf G, Riemekasten G, Radbruch A, Hiepe F, Thiel A. Simultaneous cytometric analysis of (auto)antigen-reactive T and B cell proliferation. Immunobiology. 206: 484-95. PMID 12607723 DOI: 10.1078/0171-2985-00196  0.484
2002 Dörner T, Odendahl M, Radbruch A. Zytometrische Analysen bei systemischen Autoimmunerkrankungen Zeitschrift Fur Rheumatologie. 61: 389-395. PMID 12426844 DOI: 10.1007/S00393-002-0433-3  0.405
2002 Hauser AE, Debes GF, Arce S, Cassese G, Hamann A, Radbruch A, Manz RA. Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response. Journal of Immunology (Baltimore, Md. : 1950). 169: 1277-82. PMID 12133949 DOI: 10.4049/Jimmunol.169.3.1277  0.389
2002 Manz RA, Arce S, Cassese G, Hauser AE, Hiepe F, Radbruch A. Humoral immunity and long-lived plasma cells. Current Opinion in Immunology. 14: 517-521. PMID 12088688 DOI: 10.1016/S0952-7915(02)00356-4  0.395
2002 Höfer T, Nathansen H, Löhning M, Radbruch A, Heinrich R. GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model. Proceedings of the National Academy of Sciences of the United States of America. 99: 9364-8. PMID 12087127 DOI: 10.1073/Pnas.142284699  0.368
2002 Dorner BG, Scheffold A, Rolph MS, Huser MB, Kaufmann SHE, Radbruch A, Flesch IEA, Kroczek RA. MIP-1α, MIP-1β, RANTES, and ATAC/lymphotactin function together with IFN-γ as type 1 cytokines Proceedings of the National Academy of Sciences of the United States of America. 99: 6181-6186. PMID 11972057 DOI: 10.1073/Pnas.092141999  0.401
2002 Manz RA, Radbruch A. Plasma cells for a lifetime European Journal of Immunology. 32: 923-927. PMID 11920557 DOI: 10.1002/1521-4141(200204)32:4<923::Aid-Immu923>3.0.Co;2-1  0.417
2002 Kimmig S, Przybylski GK, Schmidt CA, Laurisch K, Möwes B, Radbruch A, Thiel A. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood Journal of Experimental Medicine. 195: 789-794. PMID 11901204 DOI: 10.1084/Jem.20011756  0.442
2002 Wang YH, Stephan RP, Scheffold A, Kunkel D, Karasuyama H, Radbruch A, Cooper MD. Differential surrogate light chain expression governs B-cell differentiation. Blood. 99: 2459-67. PMID 11895780 DOI: 10.1182/Blood.V99.7.2459  0.376
2002 Assenmacher M, Scheffold A, Radbruch A. Cytometric cytokine secretion assay: Detection and isolation of cytokine-secreting T cells Methods in Microbiology. 32: 59-75. DOI: 10.1016/S0580-9517(02)32087-7  0.444
2002 Kallinich T, Loehning M, Hutloff A, Radbruch A, Hamelmann E, Kroczek RA. ICOS expression defines a subset of murine effector T cells capable to induce allergen triggered pulmonary inflammation The Journal of Allergy and Clinical Immunology. 109. DOI: 10.1016/S0091-6749(02)82109-1  0.384
2001 Assenmacher M, Löhning M, Radbruch A. Detection and Isolation of Cytokine Secreting Cells Using the Cytometric Cytokine Secretion Assay Current Protocols in Immunology. 46. PMID 18432889 DOI: 10.1002/0471142735.Im0627S46  0.427
2001 Kuon W, Holzhütter H, Appel H, Grolms M, Kollnberger S, Traeder A, Henklein P, Weiss E, Thiel A, Lauster R, Bowness P, Radbruch A, Kloetzel P, Sieper J. Identification of HLA-B27-Restricted Peptides from the Chlamydia trachomatis Proteome with Possible Relevance to HLA-B27-Associated Diseases Journal of Immunology. 167: 4738-4746. PMID 11591805 DOI: 10.4049/Jimmunol.167.8.4738  0.329
2001 Cassese G, Lindenau S, de Boer B, Arce S, Hauser A, Riemekasten G, Berek C, Hiepe F, Krenn V, Radbruch A, Manz RA. Inflamed kidneys of NZB / W mice are a major site for the homeostasis of plasma cells. European Journal of Immunology. 31: 2726-32. PMID 11536171 DOI: 10.1002/1521-4141(200109)31:9<2726::Aid-Immu2726>3.0.Co;2-H  0.354
2001 Irsch J, Wolf J, Tesch H, Diehl V, Radbruch A, Staratschek‐Jox A. Class switch recombination was specifically targeted to immunoglobulin (Ig)G4 or IgA in Hodgkin's disease-derived cell lines British Journal of Haematology. 113: 785-793. PMID 11380471 DOI: 10.1046/J.1365-2141.2001.02818.X  0.412
2001 Meisel C, Bonhagen K, Löhning M, Coyle AJ, Gutierrez-Ramos JC, Radbruch A, Kamradt T. Regulation and function of T1/ST2 expression on CD4+ T cells: Induction of type 2 cytokine production by T1/ST2 cross-linking Journal of Immunology. 166: 3143-3150. PMID 11207266 DOI: 10.4049/Jimmunol.166.5.3143  0.427
2001 Hu-Li J, Pannetier C, Guo L, Löhning M, Gu H, Watson C, Assenmacher M, Radbruch A, Paul WE. Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 14: 1-11. PMID 11163225 DOI: 10.1016/S1074-7613(01)00084-X  0.359
2000 Thiel A, Wu P, Lauster R, Braun J, Radbruch A, Sieper J. Analysis of the antigen‐specific T cell response in reactive arthritis by flow cytometry Arthritis & Rheumatism. 43: 2834-2842. PMID 11145043 DOI: 10.1002/1529-0131(200012)43:12<2834::Aid-Anr25>3.0.Co;2-7  0.431
2000 Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, Burmester GR, Lipsky PE, Radbruch A, Dörner T. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. Journal of Immunology. 165: 5970-5979. PMID 11067960 DOI: 10.4049/Jimmunol.165.10.5970  0.415
2000 Rosen O, Thiel A, Massenkeil G, Hiepe F, Häupl T, Radtke H, Burmester GR, Gromnica-Ihle E, Radbruch A, Arnold R. Autologous stem-cell transplantation in refractory autoimmune diseases after in vivo immunoablation and ex vivo depletion of mononuclear cells Arthritis Research. 2: 327-336. PMID 11056673 DOI: 10.1186/Ar107  0.318
2000 Braun J, Radbruch A, Thiel A, Sieper J, Xiang J, Brandt J, Maetzel H, Haibel H, Wu P, Kohler S, Rudwaleit M, Siegert S. Treatment of spondyloarthropathies with antibodies against tumour necrosis factor α: First clinical and laboratory experiences Annals of the Rheumatic Diseases. 59: i85-i89. PMID 11053096 DOI: 10.1136/Ard.59.Suppl_1.I85  0.369
2000 Herz U, Joachim R, Ahrens B, Scheffold A, Radbruch A, Renz H. Prenatal sensitization in a mouse model. American Journal of Respiratory and Critical Care Medicine. 162. PMID 10988153 DOI: 10.1164/Ajrccm.162.Supplement_2.Ras-1  0.394
2000 Klugewitz K, Scheffold A, Radbruch A, Hamann A. Transfer of IFNγ-depleted CD4+ T cells together with CD8+ T cells leads to rejection of murine kidney sarcoma in mice International Journal of Cancer. 87: 673-679. PMID 10925361 DOI: 10.1002/1097-0215(20000901)87:5<673::Aid-Ijc9>3.0.Co;2-H  0.431
2000 Rudwaleit M, Yin Z, Siegert S, Grolms M, Radbruch A, Braun J, Sieper J. Response to methotrexate in early rheumatoid arthritis is associated with a decrease of T cell derived tumour necrosis factor α, increase of interleukin 10, and predicted by the initial concentration of interleukin 4 Annals of the Rheumatic Diseases. 59: 311-314. PMID 10733482 DOI: 10.1136/Ard.59.4.311  0.372
2000 Herz U, Ahrens B, Scheffold A, Joachim R, Radbruch A, Renz H. Impact of in utero Th2 immunity on T cell deviation and subsequent immediate-type hypersensitivity in the neonate. European Journal of Immunology. 30: 714-718. PMID 10671232 DOI: 10.1002/1521-4141(200002)30:2<714::Aid-Immu714>3.0.Co;2-P  0.355
2000 Scheffold A, Assenmacher M, Reiners-Schramm L, Lauster R, Radbruch A. High-sensitivity immunofluorescence for detection of the pro- and anti-inflammatory cytokines gamma interferon and interleukin-10 on the surface of cytokine-secreting cells. Nature Medicine. 6: 107-110. PMID 10613835 DOI: 10.1038/71441  0.322
2000 Uthoff H, Wölk G, Scheffold A, Radbruch A, Renz H, Herz U. Impact of in utero TH-2 immunity on T-cell deviation and subsequent immediate-type hypersensitivity in the neonate The Journal of Allergy and Clinical Immunology. 109. DOI: 10.1016/S0091-6749(02)81985-6  0.353
1999 Thiel A, Radbruch A. Antigen-specific cytometry Arthritis Research & Therapy. 1: 25-29. PMID 11094410 DOI: 10.1186/Ar7  0.449
1999 Brosterhus H, Brings S, Leyendeckers H, Manz RA, Miltenyi S, Radbruch A, Assenmacher M, Schmitz J. Enrichment and detection of live antigen-specific CD4(+) and CD8(+) T cells based on cytokine secretion. European Journal of Immunology. 29: 4053-4059. PMID 10602016 DOI: 10.1002/(Sici)1521-4141(199912)29:12<4053::Aid-Immu4053>3.0.Co;2-C  0.4
1999 Karkmann U, Radbruch A, Hölzel V, Scheffold A. Enzymatic signal amplification for sensitive detection of intracellular antigens by flow cytometry. Journal of Immunological Methods. 230: 113-120. PMID 10594358 DOI: 10.1016/S0022-1759(99)00130-1  0.368
1999 Richter A, Löhning M, Radbruch A. Instruction for Cytokine Expression in T Helper Lymphocytes in Relation to Proliferation and Cell Cycle Progression Journal of Experimental Medicine. 190: 1439-1450. PMID 10562319 DOI: 10.1084/Jem.190.10.1439  0.42
1999 Yin Z, Siegert S, Neure L, Grolms M, Liu L, Eggens U, Radbruch A, Braun J, Sieper J. The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta Rheumatology. 38: 1058-1067. PMID 10556256 DOI: 10.1093/Rheumatology/38.11.1058  0.392
1999 Braun J, Yin Z, Spiller I, Siegert S, Rudwaleit M, Liu L, Radbruch A, Sieper J. Low secretion of tumor necrosis factor α, but no other Th1 or Th2 cytokines, by peripheral blood mononuclear cells correlates with chronicity in reactive arthritis Arthritis and Rheumatism. 42: 2039-2044. PMID 10524674 DOI: 10.1002/1529-0131(199910)42:10<2039::Aid-Anr3>3.0.Co;2-6  0.329
1999 Christine R, Siebenkotten G, Radbruch A. Sensitive analysis of recombination activity using integrated cell surface reporter substrates. Cytometry. 37: 205-214. PMID 10520201 DOI: 10.1002/(Sici)1097-0320(19991101)37:3<205::Aid-Cyto7>3.0.Co;2-9  0.355
1999 Irsch J, Löhndorf A, Radbruch A, König C, Krieg T, Hunzelmann N, Tesch H, Merk H. The frequency of phospholipase A2 binding of basophilic granulocytes does not decrease during bee‐venom‐specific immunotherapy Allergy. 54: 742-747. PMID 10442531 DOI: 10.1034/J.1398-9995.1999.00952.X  0.375
1999 Manz RA, Cassese G, Thiel A, Radbruch A. Long-lived plasma cells survive independent of antigen. Current Topics in Microbiology and Immunology. 246: 71-75. PMID 10396041 DOI: 10.1007/978-3-642-60162-0_9  0.368
1999 Bruno L, Scheffold A, Radbruch A, Owen MJ. Threshold of pre-T-cell-receptor surface expression is associated with αβ T-cell lineage commitment Current Biology. 9: 559-568. PMID 10359697 DOI: 10.1016/S0960-9822(99)80259-0  0.407
1999 Petry K, Siebenkotten G, Christine R, Hein K, Radbruch A. An extrachromosomal switch recombination substrate reveals kinetics and substrate requirements of switch recombination in primary murine B cells. International Immunology. 11: 753-63. PMID 10330281 DOI: 10.1093/Intimm/11.5.753  0.345
1999 Leyendeckers H, Odendahl M, Löhndorf A, Irsch J, Spangfort M, Miltenyi S, Hunzelmann N, Assenmacher M, Radbruch A, Schmitz J. Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG. European Journal of Immunology. 29: 1406-1417. PMID 10229109 DOI: 10.1002/(Sici)1521-4141(199904)29:04<1406::Aid-Immu1406>3.0.Co;2-P  0.412
1998 Romagnani S, Kapsenberg M, Radbruch A, Adorini L. Th1 and Th2 cells Research in Immunology. 149: 871-873. PMID 9923644 DOI: 10.1016/S0923-2494(99)80016-9  0.342
1998 Thiel A, Scheffold A, Radbruch A. Immunomagnetic cell sorting--pushing the limits. Immunotechnology. 4: 89-96. PMID 9853950 DOI: 10.1016/S1380-2933(98)00010-4  0.378
1998 Manz RA, Löhning M, Cassese G, Thiel A, Radbruch A. Survival of long-lived plasma cells is independent of antigen International Immunology. 10: 1703-1711. PMID 9846699 DOI: 10.1093/Intimm/10.11.1703  0.402
1998 Irsch J, Nitsch S, Hansmann ML, Rajewsky K, Tesch H, Diehl V, Jox A, Küppers R, Radbruch A. Isolation of viable Hodgkin and Reed-Sternberg cells from Hodgkin disease tissues. Proceedings of the National Academy of Sciences of the United States of America. 95: 10117-22. PMID 9707610 DOI: 10.1073/Pnas.95.17.10117  0.527
1998 Kern F, Surel IP, Brock C, Freistedt B, Radtke H, Scheffold A, Blasczyk R, Reinke P, Schneider-Mergener J, Radbruch A, Walden P, Volk H. T-Cell Epitope Mapping By Flow Cytometry Nature Medicine. 4: 975-978. PMID 9701254 DOI: 10.1038/Nm0898-975  0.318
1998 Löhning M, Stroehmann A, Coyle AJ, Grogan JL, Lin S, Gutierrez-Ramos JC, Levinson D, Radbruch A, Kamradt T. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function Proceedings of the National Academy of Sciences of the United States of America. 95: 6930-6935. PMID 9618516 DOI: 10.1073/Pnas.95.12.6930  0.403
1998 Assenmacher M, Löhning M, Scheffold A, Manz RA, Schmitz J, Radbruch A. Sequential production of IL‐2, IFN‐γ and IL‐10 by individual staphylococcal enterotoxin B‐activated T helper lymphocytes European Journal of Immunology. 28: 1534-1543. PMID 9603458 DOI: 10.1002/(Sici)1521-4141(199805)28:05<1534::Aid-Immu1534>3.0.Co;2-R  0.397
1998 Segura JA, Assenmacher M, Irsch J, Hunzelmann N, Radbruch A. Systemic T-cell unresponsiveness during rush bee-venom immunotherapy Allergy. 53: 233-240. PMID 9542602 DOI: 10.1111/J.1398-9995.1998.Tb03882.X  0.437
1998 Parronchi P, Sampognaro S, Annunziato F, Brugnolo F, Radbruch A, Modugno FD, Ruffilli A, Romagnani S, Maggi E. Influence of both TCR repertoire and severity of the atopic status on the cytokine secretion profile of Parietaria officinalis-specific T cells. European Journal of Immunology. 28: 37-46. PMID 9485184 DOI: 10.1002/(Sici)1521-4141(199801)28:01<37::Aid-Immu37>3.0.Co;2-C  0.412
1998 Scheffold A, Radbruch A. 1 Phenotyping and Separation of Leukocyte Populations Based on Affinity Labelling Methods in Microbiology. 25: 22-57. DOI: 10.1016/S0580-9517(08)70676-7  0.333
1997 Thiel A, Schmitz J, Miltenyi S, Radbruch A. CD45RA-expressing memory/effector Th cells committed to production of interferon-γ lack expression of CD31 Immunology Letters. 57: 189-192. PMID 9232450 DOI: 10.1016/S0165-2478(97)00056-4  0.44
1997 Manz RA, Thiel A, Radbruch A. Lifetime of plasma cells in the bone marrow Nature. 388: 133-134. PMID 9217150 DOI: 10.1038/40540  0.428
1997 Austrup F, Vestweber D, Borges E, Löhning M, Bräuer R, Herz U, Renz H, Hallmann R, Scheffold A, Radbruch A, Hamann A. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues Nature. 385: 81-83. PMID 8985251 DOI: 10.1038/385081A0  0.42
1997 Assenmacher M, Löhning M, Scheffold A, Richter A, Miltenyi S, Schmitz J, Radbruch A. Commitment of cytokine expression in individual TH1-like lymphocytes Immunology Letters. 56: 265. DOI: 10.1016/S0165-2478(97)86059-2  0.332
1997 Leyendeckers H, Odendahi M, Radbruch A, Miltenyi S, Assenmacher M, Schmitz J. Enrichment and analysis of antigen-specific memory B cells from blood Immunology Letters. 56: 253. DOI: 10.1016/S0165-2478(97)86007-5  0.377
1997 Richter A, Assenmacher M, Thiel A, Segura JC, Annunziato F, Maggi E, Romagnani S, Radbruch A. Cytokine cytometry: Pattern and kinetics of cytokine expression in human Th cells Immunology Letters. 56: 211. DOI: 10.1016/S0165-2478(97)85845-2  0.37
1997 Thiel A, Schmitz J, Miltenyi S, Radbruch A. Isolation and characterisation of antigen experienced CD4+ CD45RA+ CD31− human T cells from normal human peripheral blood Immunology Letters. 56: 197. DOI: 10.1016/S0165-2478(97)85789-6  0.365
1997 Manz RA, Thiel A, Miltenyi S, Radbruch A. Bone marrow plasma cells are long-lived Immunology Letters. 56: 43. DOI: 10.1016/S0165-2478(97)85163-2  0.304
1997 Petry K, Christine R, Siebenkotten G, Radbruch A. Immunoglobulin class switch recombination activity is restricted to a short period after mitogen stimulation of primary B Cells Immunology Letters. 56: 17. DOI: 10.1016/S0165-2478(97)85067-5  0.342
1996 Lorenz M, Radbruch A. Developmental and molecular regulation of immunoglobulin class switch recombination Current Topics in Microbiology and Immunology. 217: 151-169. PMID 8787624 DOI: 10.1007/978-3-642-50140-1_11  0.387
1996 Assenmacher M, Scheffold A, Schmitz J, Checa JAS, Miltenyi S, Radbruch A. Specific expression of surface interferon-gamma on interferon-gamma producing T cells from mouse and man. European Journal of Immunology. 26: 263-267. PMID 8566077 DOI: 10.1002/Eji.1830260141  0.393
1995 Scheffold A, Miltenyi S, Radbruch A. Magnetofluorescent liposomes for increased sensitivity of immunofluorescence Immunotechnology. 1: 127-137. PMID 9373341 DOI: 10.1016/1380-2933(95)00014-3  0.384
1995 Irsch J, Hunzelmann N, Tesch H, Merk H, Maggi E, Ruffilli A, Radbruch A. Isolation and characterization of allergen-binding cells from normal and allergic donors Immunotechnology. 1: 115-125. PMID 9373340 DOI: 10.1016/1380-2933(95)00012-7  0.454
1995 Wagner B, Radbruch A, Richards C, Leibold W. Monoclonal Equine Igm And Igg Immunoglobulins Veterinary Immunology and Immunopathology. 47: 1-12. PMID 8533286 DOI: 10.1016/0165-2427(94)05381-2  0.324
1995 Lorenz M, Jung S, Radbruch A. Switch transcripts in immunoglobulin class switching Science. 267: 1825-1828. PMID 7892607 DOI: 10.1126/Science.7892607  0.504
1995 Manz R, Assenmacher M, Pfluger E, Miltenyi S, Radbruch A. Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix Proceedings of the National Academy of Sciences of the United States of America. 92: 1921-1925. PMID 7892200 DOI: 10.1073/Pnas.92.6.1921  0.406
1995 Assenmacher M, Manz R, Miltenyi S, Scheffold A, Radbruch A. Fluorescence-activated cytometry cell sorting based on immunological recognition. Clinical Biochemistry. 28: 39-40. PMID 7720225 DOI: 10.1016/0009-9120(94)00063-2  0.317
1995 Radbruch A, Recktenwald D. Detection And Isolation Of Rare Cells Current Opinion in Immunology. 7: 270-273. PMID 7546388 DOI: 10.1016/0952-7915(95)80014-X  0.393
1994 Jung S, Siebenkotten G, Radbruch A. Frequency of immunoglobulin E class switching is autonomously determined and independent of prior switching to other classes. The Journal of Experimental Medicine. 179: 2023-6. PMID 8195724 DOI: 10.1084/Jem.179.6.2023  0.508
1994 Schmitz J, Thiel A, Kühn R, Rajewsky K, Müller W, Assenmacher M, Radbruch A. Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells. The Journal of Experimental Medicine. 179: 1349-53. PMID 8145047 DOI: 10.1084/Jem.179.4.1349  0.563
1994 Irsch J, Irlenbusch S, Radl J, Burrows PD, Cooper MD, Radbruch AH. Switch recombination in normal IgA1+ B lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 91: 1323-1327. PMID 8108410  0.31
1994 Klein S, Radbruch A. Inhibition of Class Switch Recombination in Plasma Cells Cellular Immunology. 157: 106-117. PMID 8039241 DOI: 10.1006/Cimm.1994.1209  0.361
1994 Schmitz B, Radbruch A, Kümmel T, Wickenhauser C, Korb H, Hansmann ML, Thiele J, Fischer R. Magnetic activated cell sorting (MACS)--a new immunomagnetic method for megakaryocytic cell isolation: comparison of different separation techniques. European Journal of Haematology. 52: 267-75. PMID 8020626 DOI: 10.1111/j.1600-0609.1994.tb00095.x  0.304
1994 Assenmacher M, Schmitz J, Radbruch A. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin-10 in interferon-γ and in interleukin-4-expressing cells European Journal of Immunology. 24: 1097-1101. PMID 7910138 DOI: 10.1002/Eji.1830240513  0.343
1994 Büsch J, Huber P, Pflüger E, Miltenyi S, Holtz J, Radbruch A. Enrichment of fetal cells from maternal blood by high gradient magnetic cell sorting (double MACS) for PCR-based genetic analysis. Prenatal Diagnosis. 14: 1129-1140. PMID 7534927 DOI: 10.1002/Pd.1970141206  0.374
1994 Radbruch A, Mechtold B, Thiel A, Miltenyi S, Pflüger E. Chapter 23 High-Gradient Magnetic Cell Sorting Methods in Cell Biology. 42: 387-403. PMID 7533249 DOI: 10.1016/S0091-679X(08)61086-9  0.335
1993 Jung S, Rajewsky K, Radbruch A. Shutdown of class switch recombination by deletion of a switch region control element. Science (New York, N.Y.). 259: 984-7. PMID 8438159 DOI: 10.1126/Science.8438159  0.589
1993 Schmitz J, Assenmacher M, Radbruch A. Regulation of T helper cell cytokine expression: functional dichotomy of antigen-presenting cells. European Journal of Immunology. 23: 191-199. PMID 8419171 DOI: 10.1002/Eji.1830230130  0.409
1993 Irsch J, Hendriks R, Tesch H, Schuurman R, Radbruch A. Evidence for a human IgG1 class switch program. European Journal of Immunology. 23: 481-486. PMID 8382164 DOI: 10.1002/Eji.1830230227  0.362
1993 Kato K, Radbruch A. Isolation and characterization of CD34+ hematopoietic stem cells from human peripheral blood by high-gradient magnetic cell sorting† Cytometry. 14: 384-392. PMID 7685679 DOI: 10.1002/Cyto.990140407  0.37
1993 Radbruch A, Assenmacher M, Kato K, Thiel A, Manz R, Scheffold A, Büsch J, Holtz J, Pflüger E, Miltenyi S. New Immunofluorescence In Flow Cytometry And Sorting: Isolation Of Rare Cells, Detection Of Rare Epitopes And Analysis Of Secretion Biology of the Cell. 79: 293-293. DOI: 10.1016/0248-4900(93)90234-6  0.307
1992 Siebenkotten G, Esser C, Radbruch A, Wabl M. The murine IgG1/IgE class switch program. European Journal of Immunology. 22: 1827-1834. PMID 1623926 DOI: 10.1002/Eji.1830220723  0.352
1992 Schmitz J, Radbruch A. Distinct antigen presenting cell-derived signals induce TH cell proliferation and expression of effector cytokines. International Immunology. 4: 43-51. PMID 1531765 DOI: 10.1093/Intimm/4.1.43  0.471
1992 illges H, radbruch A. DNA binding sites 5' of the IgG1 switch region comprising IL4 inducibility and B cell specificity. Molecular Immunology. 29: 1265-1272. PMID 1528195 DOI: 10.1016/0161-5890(92)90063-4  0.346
1992 Burger C, Radbruch A. Demethylation of the constant region genes of immunoglobulins reflects the differentiation state of the B cell Molecular Immunology. 29: 1105-1112. PMID 1379679 DOI: 10.1016/0161-5890(92)90043-W  0.377
1990 Burger C, Radbruch A. Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch TcR recombination European Journal of Immunology. 20: 2285-2291. PMID 2122953 DOI: 10.1002/Eji.1830201018  0.378
1990 Miltenyi S, Müller W, Weichel W, Radbruch A. High gradient magnetic cell separation with MACS Cytometry. 11: 231-238. PMID 1690625 DOI: 10.1002/Cyto.990110203  0.364
1989 Schmitz J, Radbruch A. An interleukin 4-induced DNase I hypersensitive site indicates opening of the γ1 switch region prior to switch recombination International Immunology. 1: 570-575. PMID 2518728 DOI: 10.1093/Intimm/1.6.570  0.319
1989 Abts H, Emmerich M, Miltenyi S, Radbruch A, Tesch H. CD20 positive human B lymphocytes separated with the magnetic cell sorter (MACS) can be induced to proliferation and antibody secretion in vitro Journal of Immunological Methods. 125: 19-28. PMID 2481694 DOI: 10.1016/0022-1759(89)90073-2  0.415
1988 Hombach J, Leclercq L, Radbruch A, Rajewsky K, Reth M. A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells. The Embo Journal. 7: 3451-3456. DOI: 10.1002/J.1460-2075.1988.Tb03219.X  0.533
1987 Yoshida N, Radbruch A, Rajewsky K. Ig gene rearrangement and expression in the progeny of B-cell progenitors in the course of clonal expansion in bone marrow cultures. The Embo Journal. 6: 2735-2741. DOI: 10.1002/J.1460-2075.1987.Tb02567.X  0.557
1986 Klein S, Gerster T, Picard D, Radbruch A, Schaffner W. Evidence for transient requirement of the IgH enhancer. Nucleic Acids Research. 13: 8901-12. PMID 3936022 DOI: 10.1093/Nar/13.24.8901  0.318
1986 Radbruch A, Müller W, Rajewsky K. Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts. Proceedings of the National Academy of Sciences of the United States of America. 83: 3954-7. PMID 3086872 DOI: 10.1073/Pnas.83.11.3954  0.558
1986 Radbruch A, Burger C, Klein S, Muller W. Control of immunoglobulin class switch recombination. Immunological Reviews. 89: 69-84. PMID 3081434 DOI: 10.1111/J.1600-065X.1986.Tb01473.X  0.349
1986 Steplewski Z, Spira G, Blaszczyk M, Lubeck MD, Radbruch A, Illges H, Herlyn D, Rajewsky K, Scharff M. Isolation and characterization of anti-monosialoganglioside monoclonal antibody 19-9 class-switch variants. Proceedings of the National Academy of Sciences of the United States of America. 82: 8653-7. PMID 2934735 DOI: 10.1073/Pnas.82.24.8653  0.512
1985 Weichel W, Liesegang B, Gehrke K, Göttlinger C, Holtkamp B, Radbruch A, Stackhouse TK, Rajewsky K. Inexpensive upgrading of a FACS I and isolation of rare somatic variants by double-fluorescence sorting. Cytometry. 6: 116-23. PMID 3979216 DOI: 10.1002/Cyto.990060206  0.478
1985 Radbruch A, Zaiss S, Kappen C, Brüggemann M, Beyreuther K, Rajewsky K. Drastic change in idiotypic but not antigen-binding specificity of an antibody by a single amino-acid substitution. Nature. 315: 506-8. PMID 2582273 DOI: 10.1038/315506A0  0.496
1984 RADBRUCH A, SABLITZKY F, RAJEWSKY K. Isotype switching in myeloma and hybridoma cells compared with LPS blasts Biochemical Society Transactions. 12: 737-737. DOI: 10.1042/Bst0120737  0.488
1984 Klein S, Sablitzky F, Radbruch A. Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant. The Embo Journal. 3: 2473-2476. DOI: 10.1002/J.1460-2075.1984.Tb02158.X  0.363
1983 Radbruch A, Brüggemann M, Liesegang B, Rajewsky K. Isolation of immunoglobulin class-switch and variable-region variants from mouse myeloma and hybridoma cell lines. Advances in Experimental Medicine and Biology. 158: 93-105. PMID 6818850 DOI: 10.1007/978-1-4899-5292-9_11  0.426
1983 Krawinkel U, Zoebelein G, Brüggemann M, Radbruch A, Rajewsky K. Recombination between antibody heavy chain variable-region genes: evidence for gene conversion. Proceedings of the National Academy of Sciences of the United States of America. 80: 4997-5001. PMID 6308665 DOI: 10.1073/Pnas.80.16.4997  0.466
1983 Radbruch A, Sablitzky F. Deletion of Cmu genes in mouse B lymphocytes upon stimulation with LPS. The Embo Journal. 2: 1929-1935. DOI: 10.1002/J.1460-2075.1983.Tb01681.X  0.368
1982 Sablitzky F, Radbruch A, Rajewsky K. Spontaneous immunoglobulin class switching in myeloma and hybridoma cell lines differs from physiological class switching. Immunological Reviews. 67: 59-72. PMID 6751996 DOI: 10.1111/J.1600-065X.1982.Tb01055.X  0.479
1982 Dildrop R, Brüggemann M, Radbruch A, Rajewsky K, Beyreuther K. Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes. The Embo Journal. 1: 635-640. DOI: 10.1002/J.1460-2075.1982.Tb01220.X  0.471
1982 Brüggemann M, Radbruch A, Rajewsky K. Immunoglobulin V region variants in hybridoma cells. I. Isolation of a variant with altered idiotypic and antigen binding specificity. The Embo Journal. 1: 629-634. DOI: 10.1002/J.1460-2075.1982.Tb01219.X  0.544
1980 Radbruch A, Liesegang B, Rajewsky K. Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class. Proceedings of the National Academy of Sciences of the United States of America. 77: 2909-13. PMID 6771763 DOI: 10.1073/Pnas.77.5.2909  0.543
1978 Liesegang B, Radbruch A, Rajewsky K. Isolation of myeloma variants with predefined variant surface immunoglobulin by cell sorting. Proceedings of the National Academy of Sciences of the United States of America. 75: 3901-5. PMID 308657 DOI: 10.1073/Pnas.75.8.3901  0.542
1977 HÄMMERLING GJ, RETH M, RADBRUCH A, HEWITT J, RAJEWSKY K. Fusion of Myeloma Cells with Mouse Lymphocytes Biochemical Society Transactions. 5: 33-33. DOI: 10.1042/Bst0050033A  0.571
Show low-probability matches.