Year |
Citation |
Score |
2023 |
Zhu Z, Tang R, Huff S, Kummetha IR, Wang L, Li N, Rana TM. Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy. Cancer Research Communications. 3: 119-129. PMID 36968224 DOI: 10.1158/2767-9764.CRC-21-0186 |
0.383 |
|
2022 |
Huff S, Kummetha IR, Zhang L, Wang L, Bray W, Yin J, Kelley V, Wang Y, Rana TM. Rational Design and Optimization of mA-RNA Demethylase FTO Inhibitors as Anticancer Agents. Journal of Medicinal Chemistry. PMID 35939803 DOI: 10.1021/acs.jmedchem.1c02075 |
0.342 |
|
2022 |
Huff SE, Winter JM, Dealwis CG. Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present. Biomolecules. 12. PMID 35740940 DOI: 10.3390/biom12060815 |
0.55 |
|
2021 |
Huff S, Kummetha IR, Tiwari SK, Huante MB, Clark AE, Wang S, Bray W, Smith D, Carlin AF, Endsley M, Rana TM. Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. Journal of Medicinal Chemistry. PMID 34570513 DOI: 10.1021/acs.jmedchem.1c00566 |
0.421 |
|
2021 |
Huff S, Tiwari SK, Gonzalez GM, Wang Y, Rana TM. mA-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. Acs Chemical Biology. PMID 33412003 DOI: 10.1021/acschembio.0c00841 |
0.39 |
|
2020 |
Li N, Kang Y, Wang L, Huff S, Tang R, Hui H, Agrawal K, Gonzalez GM, Wang Y, Patel SP, Rana TM. ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747553 DOI: 10.1073/Pnas.1918986117 |
0.319 |
|
2019 |
Sharkey M, Sharova N, Mohammed I, Huff SE, Kummetha IR, Singh G, Rana TM, Stevenson M. HIV-1 Escape from Small-Molecule Antagonism of Vif. Mbio. 10. PMID 30808702 DOI: 10.1128/Mbio.00144-19 |
0.455 |
|
2017 |
Huff SE, Mohammed FA, Yang M, Agrawal P, Pink J, Harris ME, Dealwis CG, Viswanathan R. Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase. Journal of Medicinal Chemistry. PMID 29253340 DOI: 10.1021/Acs.Jmedchem.7B00530 |
0.645 |
|
2017 |
Ahmad MF, Alam I, Huff SE, Pink J, Flanagan SA, Shewach D, Misko TA, Oleinick NL, Harte WE, Viswanathan R, Harris ME, Dealwis CG. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716944 DOI: 10.1073/Pnas.1620220114 |
0.727 |
|
2015 |
Ahmad MF, Huff SE, Pink J, Alam I, Zhang A, Perry K, Harris ME, Misko T, Porwal SK, Oleinick NL, Miyagi M, Viswanathan R, Dealwis CG. Identification of non-nucleoside human ribonucleotide reductase modulators. Journal of Medicinal Chemistry. PMID 26488902 DOI: 10.1021/Acs.Jmedchem.5B00929 |
0.337 |
|
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