Sarah E. Huff - Publications

Affiliations: 
2012-2017 Case Western Reserve University, Cleveland Heights, OH, United States 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu Z, Tang R, Huff S, Kummetha IR, Wang L, Li N, Rana TM. Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy. Cancer Research Communications. 3: 119-129. PMID 36968224 DOI: 10.1158/2767-9764.CRC-21-0186  0.383
2022 Huff S, Kummetha IR, Zhang L, Wang L, Bray W, Yin J, Kelley V, Wang Y, Rana TM. Rational Design and Optimization of mA-RNA Demethylase FTO Inhibitors as Anticancer Agents. Journal of Medicinal Chemistry. PMID 35939803 DOI: 10.1021/acs.jmedchem.1c02075  0.342
2022 Huff SE, Winter JM, Dealwis CG. Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present. Biomolecules. 12. PMID 35740940 DOI: 10.3390/biom12060815  0.55
2021 Huff S, Kummetha IR, Tiwari SK, Huante MB, Clark AE, Wang S, Bray W, Smith D, Carlin AF, Endsley M, Rana TM. Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. Journal of Medicinal Chemistry. PMID 34570513 DOI: 10.1021/acs.jmedchem.1c00566  0.421
2021 Huff S, Tiwari SK, Gonzalez GM, Wang Y, Rana TM. mA-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. Acs Chemical Biology. PMID 33412003 DOI: 10.1021/acschembio.0c00841  0.39
2020 Li N, Kang Y, Wang L, Huff S, Tang R, Hui H, Agrawal K, Gonzalez GM, Wang Y, Patel SP, Rana TM. ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747553 DOI: 10.1073/Pnas.1918986117  0.319
2019 Sharkey M, Sharova N, Mohammed I, Huff SE, Kummetha IR, Singh G, Rana TM, Stevenson M. HIV-1 Escape from Small-Molecule Antagonism of Vif. Mbio. 10. PMID 30808702 DOI: 10.1128/Mbio.00144-19  0.455
2017 Huff SE, Mohammed FA, Yang M, Agrawal P, Pink J, Harris ME, Dealwis CG, Viswanathan R. Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase. Journal of Medicinal Chemistry. PMID 29253340 DOI: 10.1021/Acs.Jmedchem.7B00530  0.645
2017 Ahmad MF, Alam I, Huff SE, Pink J, Flanagan SA, Shewach D, Misko TA, Oleinick NL, Harte WE, Viswanathan R, Harris ME, Dealwis CG. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716944 DOI: 10.1073/Pnas.1620220114  0.727
2015 Ahmad MF, Huff SE, Pink J, Alam I, Zhang A, Perry K, Harris ME, Misko T, Porwal SK, Oleinick NL, Miyagi M, Viswanathan R, Dealwis CG. Identification of non-nucleoside human ribonucleotide reductase modulators. Journal of Medicinal Chemistry. PMID 26488902 DOI: 10.1021/Acs.Jmedchem.5B00929  0.337
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