Michael Webb - Publications

Leeds, Apollo, PA, United States 

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ross JF, Wildsmith GC, Johnson M, Hurdiss D, Hollingsworth K, Thompson RF, Mosayebi M, Trinh CH, Paci E, Pearson AR, Webb ME, Turnbull WB. Directed assembly of homo-pentameric cholera toxin B-subunit proteins into higher-order structures using coiled-coil appendages. Journal of the American Chemical Society. PMID 30856321 DOI: 10.2210/Pdb6Hsv/Pdb  0.555
2017 Arnott Z, Nozaki S, Monteiro D, Morgan HE, Pearson A, Niki H, Webb ME. Mechanism of regulation of pantothenate biosynthesis by the PanD-PanZ.AcCoA complex reveals an additional mode of action for the antimetabolite N-pentyl pantothenamide (N5-Pan). Biochemistry. PMID 28832133 DOI: 10.1021/Acs.Biochem.7B00509  0.704
2015 Monteiro DC, Patel V, Bartlett CP, Nozaki S, Grant TD, Gowdy JA, Thompson GS, Kalverda AP, Snell EH, Niki H, Pearson AR, Webb ME. The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A. Chemistry & Biology. 22: 492-503. PMID 25910242 DOI: 10.1016/J.Chembiol.2015.03.017  0.724
2015 Monteiro DCF, Patel V, Bartlett CP, Nozaki S, Grant TD, Gowdy JA, Thompson GS, Kalverda AP, Snell EH, Niki H, Pearson AR, Webb ME. Towards a generalised approach for the time-resolved crystallographic study of enzymes Acta Crystallographica Section a Foundations and Advances. 71: s25-s25. DOI: 10.1107/S205327331509957X  0.547
2014 Webb ME, Yorke BA, Kershaw T, Lovelock S, Lobley CM, Kilkenny ML, Smith AG, Blundell TL, Pearson AR, Abell C. Threonine 57 is required for the post-translational activation of Escherichia coli aspartate α-decarboxylase. Acta Crystallographica. Section D, Biological Crystallography. 70: 1166-72. PMID 24699660 DOI: 10.1107/S1399004713034275  0.689
2013 Pearson A, Polyakova A, Yorke BA, Monteiro DCF, Gowdy JA, Warriner SL, Paci E, Webb ME, Beddard GS, Owen RL. Developing a set of complementary methods for time-resolved structural studies Acta Crystallographica Section a Foundations of Crystallography. 69: s282-s282. DOI: 10.1107/S0108767313097572  0.618
2012 Monteiro DC, Rugen MD, Shepherd D, Nozaki S, Niki H, Webb ME. Formation of a heterooctameric complex between aspartate α-decarboxylase and its cognate activating factor, PanZ, is CoA-dependent. Biochemical and Biophysical Research Communications. 426: 350-5. PMID 22940551 DOI: 10.1016/J.Bbrc.2012.08.084  0.658
2012 Webb ME, Lobley CM, Soliman F, Kilkenny ML, Smith AG, Blundell TL, Abell C. Structure of Escherichia coli aspartate α-decarboxylase Asn72Ala: probing the role of Asn72 in pyruvoyl cofactor formation. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 414-7. PMID 22505409 DOI: 10.1107/S1744309112009487  0.538
2005 Cheng H, Hwang I, Chong Y, Tavassoli A, Webb ME, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & Medicinal Chemistry. 13: 3593-9. PMID 15848772 DOI: 10.1016/J.Bmc.2004.11.049  0.366
2005 Webb ME, Smith AG, Abell C. Biosynthesis of Pantothenate Cheminform. 36. DOI: 10.1002/chin.200514279  0.45
2004 Webb ME, Smith AG, Abell C. Biosynthesis of pantothenate. Natural Product Reports. 21: 695-721. PMID 15565250 DOI: 10.1039/B316419P  0.428
2003 Webb ME, Stephens E, Smith AG, Abell C. Rapid screening by MALDI-TOF mass spectrometry to probe binding specificity at enzyme active sites. Chemical Communications (Cambridge, England). 2416-7. PMID 14587709 DOI: 10.1039/B308182F  0.456
2003 Lobley CM, Schmitzberger F, Kilkenny ML, Whitney H, Ottenhof HH, Chakauya E, Webb ME, Birch LM, Tuck KL, Abell C, Smith AG, Blundell TL. Structural insights into the evolution of the pantothenate-biosynthesis pathway. Biochemical Society Transactions. 31: 563-71. PMID 12773157 DOI: 10.1042/Bst0310563  0.67
2002 Saldanha SA, Birch LM, Webb ME, Nabbs BK, von Delft F, Smith AG, Abell C. Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction. Chemical Communications (Cambridge, England). 1760-1. PMID 12240302 DOI: 10.1039/B106090M  0.406
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