Ernst ter Haar, Ph.D. - Publications

Affiliations: 
Vertex Pharmaceuticals, Boston, MA, United States 
Area:
crystallography

8/60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1999 Balachandran R, ter Haar E, Yalowich JC, Welsh MJ, Grant SG, Day BW. Induction of human breast cancer cell apoptosis from G2/M preceded by stimulation into the cell cycle by Z-1,1-dichloro-2,3-diphenylcyclopropane. Biochemical Pharmacology. 57: 97-110. PMID 9920290 DOI: 10.1016/S0006-2952(98)00289-5  0.621
1998 Balachandran R, ter Haar E, Welsh MJ, Grant SG, Day BW. The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel. Anti-Cancer Drugs. 9: 67-76. PMID 9491794 DOI: 10.1097/00001813-199801000-00008  0.651
1997 ter Haar E, Hamel E, Balachandran R, Day BW. Cellular targets of the anti-breast cancer agent Z-1,1-dichloro-2,3-diphenylcyclopropane: type II estrogen binding sites and tubulin. Anticancer Research. 17: 1861-9. PMID 9216636  0.679
1997 Jonnalagadda SS, ter Haar E, Hamel E, Lin CM, Magarian RA, Day BW. Synthesis and biological evaluation of 1,1-dichloro-2,3-diarylcyclopropanes as antitubulin and anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 5: 715-22. PMID 9158870 DOI: 10.1016/S0968-0896(97)00014-X  0.593
1996 ter Haar E, Rosenkranz HS, Hamel E, Day BW. Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents. Bioorganic & Medicinal Chemistry. 4: 1659-71. PMID 8931935 DOI: 10.1016/0968-0896(96)00158-7  0.473
1996 ter Haar E, Day BW. Cytostatic and cytotoxic action of Z-1, 1-dichloro-2,3-diphenylcyclopropane in three human breast cancer cell lines. Anticancer Research. 16: 1107-15. PMID 8702221  0.64
1996 ter Haar E, Day BW, Rosenkranz HS. Direct tubulin polymerization perturbation contributes significantly to the induction of micronuclei in vivo. Mutation Research. 350: 331-7. PMID 8600362 DOI: 10.1016/0027-5107(95)00175-1  0.457
1996 ter Haar E, Kowalski RJ, Hamel E, Lin CM, Longley RE, Gunasekera SP, Rosenkranz HS, Day BW. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol. Biochemistry. 35: 243-50. PMID 8555181 DOI: 10.1021/Bi9515127  0.582
Low-probability matches (unlikely to be authored by this person)
2008 Farmer LJ, Bemis G, Britt SD, Cochran J, Connors M, Harrington EM, Hoock T, Markland W, Nanthakumar S, Taslimi P, Ter Haar E, Wang J, Zhaveri D, Salituro FG. Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK). Bioorganic & Medicinal Chemistry Letters. 18: 6231-5. PMID 18938080 DOI: 10.1016/j.bmcl.2008.09.106  0.243
1998 ter Haar E. Taxanes and other microtubule stabilising agents Expert Opinion On Therapeutic Patents. 8: 571-586. DOI: 10.1517/13543776.8.5.571  0.218
2009 Aronov AM, Tang Q, Martinez-Botella G, Bemis GW, Cao J, Chen G, Ewing NP, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Markland W, ... ... ter Haar E, et al. Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. Journal of Medicinal Chemistry. 52: 6362-8. PMID 19827834 DOI: 10.1021/Jm900630Q  0.178
2016 Bonafoux D, Nanthakumar S, Bandarage UK, Memmott C, Lowe DB, Aronov AM, Bhisetti Rao G, Bonanno K, Coll J, Leeman J, Lepre CA, Lu F, Perola E, Rijnbrand R, Taylor WP, ... ... Ter Haar E, et al. Fragment-based discovery of dual JC virus and BK virus helicase inhibitors. Journal of Medicinal Chemistry. PMID 27385654 DOI: 10.1021/acs.jmedchem.6b00486  0.177
2016 Capoferri L, Leth R, Ter Haar E, Mohanty AK, Grootenhuis PD, Vottero E, Commandeur JN, Vermeulen NP, Jørgensen FS, Olsen L, Geerke DP. Insights into regioselective metabolism of mefenamic acid by Cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations. Proteins. PMID 26757175 DOI: 10.1002/Prot.24985  0.171
2007 ter Haar E, Prabhakar P, Prabakhar P, Liu X, Lepre C. Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimer. The Journal of Biological Chemistry. 282: 9733-9. PMID 17255097 DOI: 10.1074/jbc.M611165200  0.136
1997 Cupers P, ter Haar E, Boll W, Kirchhausen T. Parallel dimers and anti-parallel tetramers formed by epidermal growth factor receptor pathway substrate clone 15. The Journal of Biological Chemistry. 272: 33430-4. PMID 9407139 DOI: 10.1074/Jbc.272.52.33430  0.13
2004 Sagredo V, Pineda F, Ter Haar E. Magnetic properties of the Mn1-xFexIn 2S4 spinel compounds Journal of Alloys and Compounds. 369: 84-86. DOI: 10.1016/j.jallcom.2003.09.076  0.112
2003 Betancourt L, Sagredo V, Delgado G, Ter Haar E. Magnetic behavior and structural characterization of the semiconducting compound CdGa0.3Cr1.7S4 Revista Mexicana De Fisica. 49: 201-203.  0.107
2010 ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM. Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism. Structure (London, England : 1993). 18: 1083-93. PMID 20826335 DOI: 10.1016/J.Str.2010.05.014  0.106
2001 ter Haar E, Coll JT, Austen DA, Hsiao HM, Swenson L, Jain J. Structure of GSK3beta reveals a primed phosphorylation mechanism. Nature Structural Biology. 8: 593-6. PMID 11427888 DOI: 10.1038/89624  0.09
2010 Arnost M, Pierce A, ter Haar E, Lauffer D, Madden J, Tanner K, Green J. 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta. Bioorganic & Medicinal Chemistry Letters. 20: 1661-4. PMID 20138514 DOI: 10.1016/j.bmcl.2010.01.072  0.089
2002 Meng W, Swenson LL, Fitzgibbon MJ, Hayakawa K, Ter Haar E, Behrens AE, Fulghum JR, Lippke JA. Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export. The Journal of Biological Chemistry. 277: 37401-5. PMID 12171911 DOI: 10.1074/jbc.C200418200  0.077
2004 ter Haar E, Walters WP, Pazhanisamy S, Taslimi P, Pierce AC, Bemis GW, Salituro FG, Harbeson SL. Kinase chemogenomics: targeting the human kinome for target validation and drug discovery. Mini Reviews in Medicinal Chemistry. 4: 235-53. PMID 15032672 DOI: 10.2174/1389557043487367  0.076
1991 Thomas AA, ter Haar E, Wellink J, Voorma HO. Cowpea mosaic virus middle component RNA contains a sequence that allows internal binding of ribosomes and that requires eukaryotic initiation factor 4F for optimal translation. Journal of Virology. 65: 2953-9. PMID 2033661 DOI: 10.1128/jvi.65.6.2953-2959.1991  0.073
2003 ter Haar E. Activating MAP KAP kinase 2. Structure (London, England : 1993). 11: 611-2. PMID 12791249 DOI: 10.1016/S0969-2126(03)00104-7  0.069
2000 ter Haar E, Harrison SC, Kirchhausen T. Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proceedings of the National Academy of Sciences of the United States of America. 97: 1096-100. PMID 10655490 DOI: 10.1073/Pnas.97.3.1096  0.058
1995 ter Haar E, Wagner R, van Woerkens CMCM, Steel SC, Frossati G, Skrbek L, Meisel MW, Bindilatti V, Rodrigues AR, Martin RV, Oliveira NF. Plastic dilution refrigerators Journal of Low Temperature Physics. 99: 151-166. DOI: 10.1007/Bf00753626  0.057
1996 Bindilatti V, Oliveira NF, ter Haar E, Shapira Y. Magnetic interactions in diluted systems from low temperature magnetization steps Czechoslovak Journal of Physics. 46: 3255-3262. DOI: 10.1007/Bf02548138  0.055
1998 ter Haar E, Musacchio A, Harrison SC, Kirchhausen T. Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker. Cell. 95: 563-73. PMID 9827808 DOI: 10.1016/S0092-8674(00)81623-2  0.054
2000 Gratens X, Bindilatti V, Ter Haar E, Oliveira NF, Shapira Y, Golacki Z. Magnetization steps from Ce3+-pairs in Pb1-xCexSe Physica B: Condensed Matter. 284: 1519-1520.  0.051
1998 Bindilatti V, Ter Haar E, Oliveira NF, Liu MT, Shapira Y, Gratens X, Charar S, Isber S, Masri P, Averous M, Golacki Z, McNiff EJ. Magnetization steps in Pb1-xEuxS: Exchange and anisotropic interactions Physical Review B - Condensed Matter and Materials Physics. 57: 7854-7862.  0.049
2001 Gratens X, Bindilatti V, Ter Haar E, Oliveira NF, Shapira Y, Montenegro FC. Magnetization steps in Mn0.084Zn0.916F2: Exchange constant and Mn distribution Physical Review B - Condensed Matter and Materials Physics. 64: 2144241-2144248.  0.048
2000 Gratens X, Ter Haar E, Bindilatti V, Oliveira NF, Shapira Y, Liu MT, Golacki Z, Charar S, Errebbahi A. Magnetization steps in Sn1-xEuxTe: Eu-Eu exchange and Eu distribution Journal of Physics Condensed Matter. 12: 3711-3718. DOI: 10.1088/0953-8984/12/15/317  0.047
2004 Mantilla J, Brito GES, Ter Haar E, Sagredo V, Bindilatti V. The structure of Zn1-xMnxIn2Se4 crystals grown by chemical vapour phase transport Journal of Physics Condensed Matter. 16: 3555-3562. DOI: 10.1088/0953-8984/16/21/005  0.045
1999 Bindilatti V, Ter Haar E, Oliveira NF, Shapira Y, Liu MT. Distant-neighbor exchange constants in Mn-based dilute magnetic semiconductors Journal of Applied Physics. 85: 5950-5952.  0.042
1999 Bindilatti V, Oliveira NF, Ter Haar E, Shapira Y. Antiferromagnetic interactions in diluted systems from 20 mK magnetometry Materials Science Forum. 302: 363-370.  0.041
2005 Sagredo V, Delgado GE, Ter Haar E, Attolini G. Crystal growth and characterization of MnIn2-2x Ga2x Se4 Journal of Crystal Growth. 275: e521-e524. DOI: 10.1016/j.jcrysgro.2004.11.025  0.04
2008 Bouman B, Morskieft E, Ter Haar E, Pieters P. SIL classification for intelligent motor control systems in accordance with the ATEX directive 5th Pcic Europe 2008: Petroleum and Chemical Industry Conference Europe. DOI: 10.1109/PCICEUROPE.2008.4563546  0.04
2004 Henriques AB, Hanamoto LK, Ter Haar E, Abramof E, Ueta AY, Rappl PHO. Tuning of the magnetic field induced sharp band-edge optical absorption in europium chalcogenides International Journal of Modern Physics B. 18: 3813-3816. DOI: 10.1142/S0217979204027505  0.04
1997 Ter Haar E, Bindilatti V, Oliveira NF, McCabe GH, Shapira Y, Golacki Z, Charar S, Averous M, McNiff EJ. Eu-Eu exchange interaction and Eu distribution in Pb1-xEuxTe from magnetization steps Physical Review B - Condensed Matter and Materials Physics. 56: 8912-8918.  0.038
2008 Mantilla J, Ter Haar E, Coaquira JAH, Bindilatti V. Experimental evidence of the spin-glass transition in the diluted magnetic semiconductor Zn1-xMnxIn2Se4 Journal of Physics Condensed Matter. 20. DOI: 10.1088/0953-8984/20/45/455211  0.038
2001 Gratens X, Ter Haar E, Bindilatti V, Oliveira NF, Shapira Y, Golacki Z. Magnetization steps in Pb1-xCexS at 20mK Journal of Magnetism and Magnetic Materials. 226: 2036-2037.  0.035
1994 ter Haar E, Frossati G, Clark WG. Brute force nuclear polarization of D2 Physica B: Physics of Condensed Matter. 194: 945-946. DOI: 10.1016/0921-4526(94)90802-8  0.034
1982 Ter Haar E. Recreation in new areas: the IJsselmeerpolders as case study ( Netherlands). Polders of the World. Papers International Symposium, Lelystad, 1982. Volume 2, (International Institute For Land Reclamation and Improvement, Wageningen). 457-468.  0.034
1982 ter Haar E. RECREATION IN NEW AREAS; THE IJSSELMEERPOLDERS AS CASE-STUDY. . 457-468.  0.034
2002 Sagredo V, Ter Haar E, Attolini G. Magnetic properties of MnGa(2))Se4)-MnIn(2)Se(4) single crystal semiconductors Physica B: Condensed Matter. 320: 407-409. DOI: 10.1016/S0921-4526(02)00760-3  0.033
1983 Cuypers HT, Ter Haar EM, Jansen PL. Microsomal conjugation and oxidation of bilirubin. Biochimica Et Biophysica Acta. 758: 135-43. PMID 6871245 DOI: 10.1016/0304-4165(83)90294-5  0.033
2005 Pierce AC, ter Haar E, Binch HM, Kay DP, Patel SR, Li P. CH...O and CH...N hydrogen bonds in ligand design: a novel quinazolin-4-ylthiazol-2-ylamine protein kinase inhibitor. Journal of Medicinal Chemistry. 48: 1278-81. PMID 15715498 DOI: 10.1021/jm0492249  0.031
2004 Silva P, De Chalbaud L, Ter Haar E, Sagredo V. Magnetic properties of the reentrant CdGa2-2xCr 2xSe4 Journal of Magnetism and Magnetic Materials. 272: e1551-e1552. DOI: 10.1016/j.jmmm.2003.12.802  0.029
1998 Bindilatti V, Ter Haar E, Oliveira NF, Shapira Y, Liu MT. Distant-neighbor exchange constants in dilute magnetic semiconductors Physical Review Letters. 80: 5425-5428.  0.028
2004 Ochoa JCM, Bindilatti V, Ter Haar E, Coaquira JAH, De Souza Brito GE, Gratens X, Sagredo V. Spin glass behavior in MnIn2Se4 and Zn 1-xMnxIn2Se4 magnetic semiconductors Journal of Magnetism and Magnetic Materials. 272: 1308-1309. DOI: 10.1016/j.jmmm.2003.12.1080  0.027
2000 Honig A, Wei X, Lewis A, Ter Haar E, Seraji-Bozorgzad K. High equilibrium spin polarizations in solid 129Xe Physica B: Condensed Matter. 284: 2049-2050.  0.027
2001 Cajacuri RA, Gratens X, Ter Haar E, Bindilatti V, Oliveira NF, Shapira Y, Golacki Z. Distant-neighbors exchange constants in Cd1-xMnxSe from magnetization steps Journal of Magnetism and Magnetic Materials. 226: 1981-1982.  0.027
2006 Ter Haar E. The Crystal Structures of Glycogen Synthase Kinase 3 Glycogen Synthase Kinase 3 (Gsk-3) and Its Inhibitors: Drug Discovery and Development. 61-82. DOI: 10.1002/9780470052174.ch4  0.027
1996 ter Haar E, van Woerkens CMCM. Thermal links in high fields and low temperatures Czechoslovak Journal of Physics. 46: 2731-2732. DOI: 10.1007/BF02570352  0.026
2011 Chakravarthy B, Ter Haar E, Bhat SS, McCoy CE, Denmark TK, Lotfipour S. Simulation in medical school education: review for emergency medicine. The Western Journal of Emergency Medicine. 12: 461-6. PMID 22224138 DOI: 10.5811/westjem.2010.10.1909  0.021
1996 Oliveira NF, Bindilatti V, ter Haar E, Martin RV, McNiff EJ. A plastic dilution refrigerator in a 35 T magnet Czechoslovak Journal of Physics. 46: 2787-2788. DOI: 10.1007/BF02570380  0.02
1994 Bindilatti V, ter Haar E, Rodrigues AR, Oliveira NF, Frossati G. Effect of longitudinal vibration on the final temperature of a plastic dilution refrigerator. The possibility of its use as a vibrating sample magnetometer. Physica B: Physics of Condensed Matter. 194: 37-38. DOI: 10.1016/0921-4526(94)90348-4  0.019
2004 Ter Haar E, Martin RV. Phase boundary detection for dilution refrigerators Review of Scientific Instruments. 75: 3071-3073. DOI: 10.1063/1.1784568  0.017
1984 Cuypers HT, ter Haar EM, Jansen PL. UDP-glucuronyltransferase-catalyzed deconjugation of bilirubin monoglucuronide. Hepatology (Baltimore, Md.). 4: 918-22. PMID 6434392  0.015
1996 Coccia E, Fafone V, Frossati G, Ter Haar E, Meisel MW. Eigenfrequencies and quality factors of vibration of aluminium alloy spherical resonators Physics Letters, Section a: General, Atomic and Solid State Physics. 219: 263-270.  0.01
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