Guangyu Zhu, Ph.D. - Publications

Biology & Chemistry City University of Hong Kong, Kowloon, Hong Kong 
chemical biology, DNA repair

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Deng Z, Wang N, Liu Y, Xu Z, Wang Z, Lau TC, Zhu G. A photocaged, water-oxidizing, and nucleolus-targeted Pt(IV) complex with a distinct anticancer mechanism. Journal of the American Chemical Society. PMID 32216337 DOI: 10.1021/jacs.0c00221  0.44
2019 Cai L, Wang Y, Gao H, Ma X, Zhu G, Zhang R, Shen X, Luo X. Some Effects of Different Constitutive Laws on FSI Simulation for the Mitral Valve. Scientific Reports. 9: 12753. PMID 31484963 DOI: 10.1038/s41598-019-49161-6  0.52
2019 Wang Z, Deng Z, Zhu G. Emerging platinum(iv) prodrugs to combat cisplatin resistance: from isolated cancer cells to tumor microenvironment. Dalton Transactions (Cambridge, England : 2003). PMID 30633263 DOI: 10.1039/c8dt03923b  0.44
2018 Xu Z, Chan HM, Li C, Wang Z, Tse MK, Tong Z, Zhu G. Synthesis, Structure, and Cytotoxicity of Oxaliplatin-Based Platinum(IV) Anticancer Prodrugs Bearing One Axial Fluoride. Inorganic Chemistry. PMID 29943979 DOI: 10.1021/acs.inorgchem.8b00706  0.44
2018 Wang N, Wang Z, Xu Z, Chen X, Zhu G. A cisplatin-loaded immuno-chemotherapeutic nanohybrid bearing immune checkpoint inhibitors for enhanced cervical cancer therapy. Angewandte Chemie (International Ed. in English). PMID 29405579 DOI: 10.1002/anie.201800422  0.44
2017 Yan L, Chen X, Wang Z, Zhang X, Zhu X, Zhou M, Chen W, Huang L, Roy VAL, Yu PKN, Zhu G, Zhang W. Size Controllable and Surface Tunable Zeolitic Imidazolate Framework-8 (ZIF-8)-Poly(acrylic acid sodium salt) (PAAS) Nanocomposites for pH Responsive Drug Release and Enhanced In Vivo Cancer Treatment. Acs Applied Materials & Interfaces. PMID 28876048 DOI: 10.1021/acsami.7b10064  0.44
2017 Yan L, Wang Z, Chen X, Gou XJ, Zhang Z, Zhu X, Lan M, Chen W, Zhu G, Zhang W. Firmly anchored photosensitizer Chlorin e6 to layered double hydroxide nanoflakes for highly efficient photodynamic therapy in vivo. Chemical Communications (Cambridge, England). PMID 28164197 DOI: 10.1039/c6cc09510k  0.44
2017 Li W, Xu Z, Xu B, Chan CY, Lin X, Wang Y, Chen G, Wang Z, Yuan Q, Zhu G, Sun H, Wu W, Shi P. Investigation of the Subcellular Neurotoxicity of Amyloid-β Using a Device Integrating Microfluidic Perfusion and Chemotactic Guidance. Advanced Healthcare Materials. PMID 28121396 DOI: 10.1002/adhm.201600895  0.44
2016 Yu WK, Wang Z, Fong CC, Liu D, Yip TC, Au SK, Zhu G, Yang M. Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin-DNA damage. British Journal of Pharmacology. PMID 27933604 DOI: 10.1111/bph.13690  0.44
2016 Wang Z, Xu Z, Zhu G. A Platinum(IV) Anticancer Prodrug Targeting Nucleotide Excision Repair To Overcome Cisplatin Resistance. Angewandte Chemie (International Ed. in English). PMID 27736029 DOI: 10.1002/anie.201608936  0.44
2016 Ma L, Ma R, Wang Z, Yiu SM, Zhu G. Heterodinuclear Pt(iv)-Ru(ii) anticancer prodrugs to combat both drug resistance and tumor metastasis. Chemical Communications (Cambridge, England). PMID 27506281 DOI: 10.1039/c6cc04354b  0.44
2016 Ai F, Sun T, Xu Z, Wang Z, Kong W, To MW, Wang F, Zhu G. An upconversion nanoplatform for simultaneous photodynamic therapy and Pt chemotherapy to combat cisplatin resistance. Dalton Transactions (Cambridge, England : 2003). PMID 27430044 DOI: 10.1039/c6dt01404f  0.44
2016 Zhang X, Ai F, Sun T, Wang F, Zhu G. Multimodal Upconversion Nanoplatform with a Mitochondria-Targeted Property for Improved Photodynamic Therapy of Cancer Cells. Inorganic Chemistry. PMID 27049165 DOI: 10.1021/acs.inorgchem.6b00020  0.64
2016 Zhu X, Yuen MF, Yan L, Zhang Z, Ai F, Yang Y, Yu PK, Zhu G, Zhang W, Chen X. Diamond-Nanoneedle-Array-Facilitated Intracellular Delivery and the Potential Influence on Cell Physiology. Advanced Healthcare Materials. PMID 26992125 DOI: 10.1002/adhm.201500990  0.64
2016 Pang W, Lou N, Jin C, Hu C, Arvine C, Zhu G, Shen X. Combination of preoperative platelet/lymphocyte and neutrophil/lymphocyte rates and tumor-related factors to predict lymph node metastasis in patients with gastric cancer. European Journal of Gastroenterology & Hepatology. PMID 26854795 DOI: 10.1097/MEG.0000000000000563  0.52
2016 Sun W, Yan M, Ai S, Zhu G, Wang Z, Liu L, Xu Y, Ren J. Ice Temperature characteristics of the Austre Lovénbreen glacier in NY-Ålesund, arctic region Wuhan Daxue Xuebao (Xinxi Kexue Ban)/Geomatics and Information Science of Wuhan University. 41: 79-85. DOI: 10.13203/j.whugis20150302  0.44
2016 Zhen S, Zhou J, Deng X, Zhu G, Cao H, Wang Z, Yan Y. Metabolite profiling of the response to high-nitrogen fertilizer during grain development of bread wheat (Triticum aestivum L.) Journal of Cereal Science. 69: 85-94. DOI: 10.1016/j.jcs.2016.02.014  0.44
2016 Wu S, Shen X, Zhu G, Zhou H, Ji Z, Chen K, Yuan A. Synthesis of ternary Ag/ZnO/ZnFe2O4 porous and hollow nanostructures with enhanced photocatalytic activity Applied Catalysis B: Environmental. 184: 328-336. DOI: 10.1016/j.apcatb.2015.11.035  0.52
2016 Lei J, Jiang T, Wu K, du H, Zhu G, Wang Z. Robust K-means algorithm with automatically splitting and merging clusters and its applications for surveillance data Multimedia Tools and Applications. 1-17. DOI: 10.1007/s11042-016-3322-5  0.44
2015 Wu S, Shen X, Zhou H, Zhu G, Wang R, Ji Z, Chen K, Chen C. Morphological synthesis of Prussian blue analogue Zn3[Fe(CN)6]2⋅xH2O micro-/nanocrystals and their excellent adsorption performance toward methylene blue. Journal of Colloid and Interface Science. 464: 191-197. PMID 26619129 DOI: 10.1016/j.jcis.2015.11.036  0.52
2015 He X, Zhu G, Yang J, Chang H, Meng Q, Zhao H, Zhou X, Yue S, Wang Z, Shi J, Gu L, Yan D, Weng Y. Photogenerated Intrinsic Free Carriers in Small-molecule Organic Semiconductors Visualized by Ultrafast Spectroscopy. Scientific Reports. 5: 17076. PMID 26611323 DOI: 10.1038/srep17076  0.44
2015 Xu Z, Wang Z, Yiu SM, Zhu G. Mono- and di-bromo platinum(iv) prodrugs via oxidative bromination: synthesis, characterization, and cytotoxicity. Dalton Transactions (Cambridge, England : 2003). PMID 26514681 DOI: 10.1039/c5dt03101j  0.64
2015 Yang FX, Zhu GF, Wang Z, Liu HL, Huang D. A putative miR172-targeted CeAPETALA2-like gene is involved in floral patterning regulation of the orchid Cymbidium ensifolium. Genetics and Molecular Research : Gmr. 14: 12049-61. PMID 26505352 DOI: 10.4238/2015.October.5.18  0.44
2015 Liu D, Shen X, Zhu G, Xing M. REC8 is a novel tumor suppressor gene epigenetically robustly targeted by the PI3K pathway in thyroid cancer. Oncotarget. PMID 26472282 DOI: 10.18632/oncotarget.5391  0.52
2015 Wang S, Li L, Chen J, Li X, Yin J, Liu K, Li C, Wang Z, Li C, Zhu G. Effects of free fat grafting on the prevention of Frey's syndrome and facial depression after parotidectomy: A prospective randomized trial. The Laryngoscope. PMID 26451695 DOI: 10.1002/lary.25714  0.44
2015 Zhang J, Liang YC, Lin X, Zhu X, Yan L, Li S, Yang X, Zhu G, Rogach AL, Yu PK, Shi P, Tu LC, Chang CC, Zhang X, Chen X, et al. Self-Monitoring and Self-Delivery of Photosensitizer-Doped Nanoparticles for Highly Effective Combination Cancer Therapy in Vitro and in Vivo. Acs Nano. PMID 26390118 DOI: 10.1021/acsnano.5b02513  0.64
2015 Jacobson O, Weiss I, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu G, Kiesewetter DO, Vasdev N, Liang S, Chen X. 18F-labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26315836 DOI: 10.2967/jnumed.115.160960  0.44
2015 Wang Z, Ma R, Yan L, Chen X, Zhu G. Combined chemotherapy and photodynamic therapy using a nanohybrid based on layered double hydroxides to conquer cisplatin resistance. Chemical Communications (Cambridge, England). 51: 11587-90. PMID 26096645 DOI: 10.1039/c5cc04376j  0.64
2015 Zhu G, Yang F, Shi S, Li D, Wang Z, Liu H, Huang D, Wang C. Transcriptome Characterization of Cymbidium sinense 'Dharma' Using 454 Pyrosequencing and Its Application in the Identification of Genes Associated with Leaf Color Variation. Plos One. 10: e0128592. PMID 26042676 DOI: 10.1371/journal.pone.0128592  0.44
2015 Ai F, Ju Q, Zhang X, Chen X, Wang F, Zhu G. A core-shell-shell nanoplatform upconverting near-infrared light at 808 nm for luminescence imaging and photodynamic therapy of cancer. Scientific Reports. 5: 10785. PMID 26035527 DOI: 10.1038/srep10785  0.64
2015 Li Z, Dai H, Martos SN, Xu B, Gao Y, Li T, Zhu G, Schones DE, Wang Z. Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells. Genome Biology. 16: 115. PMID 26032981 DOI: 10.1186/s13059-015-0685-2  0.44
2015 Zhu G, Zhu X, Dai Z, Wang Z, Zhu C. Analytical model of optical path difference in an end-pumped Yb:YAG thin-disk laser with nonuniform pumping light. Applied Optics. 54: 3024-31. PMID 25967218  0.44
2015 Zhu G, Wang L, Guo H, Lu L, Yang S, Wang T, Guo H, Wang H, Min J, Yang K, Chen X, Liu Y, Wang Z, Su H. DNA Repair Genes XRCC1 and ERCC1 Polymorphisms and the Risk of Sporadic Breast Cancer in Han Women in the Gansu Province of China. Genetic Testing and Molecular Biomarkers. PMID 25961110 DOI: 10.1089/gtmb.2015.0001  0.44
2015 Lin ZW, Wang Z, Zhu GP, Li BW, Xie WL, Xiang DC. Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats. International Journal of Clinical and Experimental Medicine. 8: 2118-27. PMID 25932142  0.44
2015 Ma R, Wang Y, Yan L, Ma L, Wang Z, Chan HC, Chiu SK, Chen X, Zhu G. Efficient co-delivery of a Pt(IV) prodrug and a p53 activator to enhance the anticancer activity of cisplatin. Chemical Communications (Cambridge, England). 51: 7859-62. PMID 25854514 DOI: 10.1039/c4cc09879j  0.64
2015 Ma L, Ma R, Wang Y, Zhu X, Zhang J, Chan HC, Chen X, Zhang W, Chiu SK, Zhu G. Chalcoplatin, a dual-targeting and p53 activator-containing anticancer platinum(IV) prodrug with unique mode of action. Chemical Communications (Cambridge, England). 51: 6301-4. PMID 25644651 DOI: 10.1039/c4cc10409a  0.64
2015 Wang Z, Ai F, Wang Z, Zhao W, Zhu G, Lin Z, Sun J. Organocatalytic asymmetric synthesis of 1,1-diarylethanes by transfer hydrogenation. Journal of the American Chemical Society. 137: 383-9. PMID 25482291 DOI: 10.1021/ja510980d  0.64
2015 Ju Q, Chen X, Ai F, Peng D, Lin X, Kong W, Shi P, Zhu G, Wang F. An upconversion nanoprobe operating in the first biological window Journal of Materials Chemistry B. 3: 3548-3555. DOI: 10.1039/c5tb00025d  0.64
2015 Shen X, Liu Q, Ji Z, Zhu G, Zhou H, Chen K. Controlled synthesis and gas sensing properties of porous Fe2O3/NiO hierarchical nanostructures Crystengcomm. 17: 5522-5529. DOI: 10.1039/c5ce00840a  0.52
2015 Zhu G, Guo L, Shen X, Ji Z, Chen K, Zhou H. Monodispersed In2O3 mesoporous nanospheres: One-step facile synthesis and the improved gas-sensing performance Sensors and Actuators, B: Chemical. 220: 977-985. DOI: 10.1016/j.snb.2015.06.036  0.52
2015 Zhu G, Xi C, Liu Y, Bao C, Shen X, Ma L, Pang H. Easy fabrication of ultralight CNx foams with application as absorbents and continuous flow oil-water separation Materials Today Communications. 4: 116-123. DOI: 10.1016/j.mtcomm.2015.06.001  0.52
2015 Zhu X, Kwok SY, Yuen MF, Yan L, Chen W, Yang Y, Wang Z, Yu KN, Zhu G, Zhang W, Chen X. Dense diamond nanoneedle arrays for enhanced intracellular delivery of drug molecules to cell lines Journal of Materials Science. 50: 7800-7807. DOI: 10.1007/s10853-015-9351-z  0.64
2014 Ma R, Wang Z, Yan L, Chen X, Zhu G. Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug. Journal of Materials Chemistry. B. 2: 4868-4875. PMID 32261778 DOI: 10.1039/c4tb00645c  0.44
2014 Wang B, Wang Z, Ai F, Tang WK, Zhu G. A monofunctional platinum(II)-based anticancer agent from a salicylanilide derivative: Synthesis, antiproliferative activity, and transcription inhibition. Journal of Inorganic Biochemistry. 142: 118-125. PMID 25450026 DOI: 10.1016/j.jinorgbio.2014.10.003  0.64
2014 Wang Y, Yang Y, Yan L, Kwok SY, Li W, Wang Z, Zhu X, Zhu G, Zhang W, Chen X, Shi P. Poking cells for efficient vector-free intracellular delivery. Nature Communications. 5: 4466. PMID 25072981 DOI: 10.1038/ncomms5466  0.64
2014 Wang B, Qian H, Yiu SM, Sun J, Zhu G. Platinated benzonaphthyridone is a stronger inhibitor of poly(ADP-ribose) polymerase-1 and a more potent anticancer agent than is the parent inhibitor. European Journal of Medicinal Chemistry. 71: 366-73. PMID 24361480 DOI: 10.1016/j.ejmech.2013.10.062  0.64
2014 Wang Z, Qian H, Yiu SM, Sun J, Zhu G. Multi-targeted organometallic ruthenium(II)-arene anticancer complexes bearing inhibitors of poly(ADP-ribose) polymerase-1: A strategy to improve cytotoxicity. Journal of Inorganic Biochemistry. 131: 47-55. PMID 24239912 DOI: 10.1016/j.jinorgbio.2013.10.017  0.64
2014 Yan L, Raphael AP, Zhu X, Wang B, Chen W, Tang T, Deng Y, Sant HJ, Zhu G, Choy KW, Gale BK, Prow TW, Chen X. Nanocomposite-strengthened dissolving microneedles for improved transdermal delivery to human skin. Advanced Healthcare Materials. 3: 555-64. PMID 24173960 DOI: 10.1002/adhm.201300312  0.64
2014 Ma R, Wang Z, Yan L, Chen X, Zhu G. Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug Journal of Materials Chemistry B. 2: 4868-4875. DOI: 10.1039/c4tb00645c  0.64
2014 Chen W, Wang C, Yan L, Huang L, Zhu X, Chen B, Sant HJ, Niu X, Zhu G, Yu KN, Roy VAL, Gale BK, Chen X. Improved polyvinylpyrrolidone microneedle arrays with non-stoichiometric cyclodextrin Journal of Materials Chemistry B. 2: 1699-1705. DOI: 10.1039/c3tb21698e  0.64
2013 Wen H, Zhu H, Chen X, Hung TF, Wang B, Zhu G, Yu SF, Wang F. Upconverting near-infrared light through energy management in core-shell-shell nanoparticles. Angewandte Chemie (International Ed. in English). 52: 13419-23. PMID 24132883 DOI: 10.1002/anie.201306811  0.64
2013 Yan L, Chen W, Zhu X, Huang L, Wang Z, Zhu G, Roy VA, Yu KN, Chen X. Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery. Chemical Communications (Cambridge, England). 49: 10938-40. PMID 24129414 DOI: 10.1039/c3cc45714a  0.64
2013 Zhu G, Song L, Lippard SJ. Visualizing inhibition of nucleosome mobility and transcription by cisplatin-DNA interstrand crosslinks in live mammalian cells. Cancer Research. 73: 4451-60. PMID 23695549 DOI: 10.1158/0008-5472.CAN-13-0198  0.64
2013 Chen X, Zhu G, Yang Y, Wang B, Yan L, Zhang KY, Lo KK, Zhang W. A diamond nanoneedle array for potential high-throughput intracellular delivery. Advanced Healthcare Materials. 2: 1103-7. PMID 23447527 DOI: 10.1002/adhm.201200362  0.64
2013 Chen Z, Wang B, Wang Z, Zhu G, Sun J. Complex bioactive alkaloid-type polycycles through efficient catalytic asymmetric multicomponent aza-Diels-Alder reaction of indoles with oxetane as directing group. Angewandte Chemie (International Ed. in English). 52: 2027-31. PMID 23303578 DOI: 10.1002/anie.201206481  0.64
2012 Zhu G, Myint M, Ang WH, Song L, Lippard SJ. Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cells. Cancer Research. 72: 790-800. PMID 22180496 DOI: 10.1158/0008-5472.CAN-11-3151  0.64
2012 Daghestani HN, Zhu G, Johnston PA, Shinde SN, Brodsky JL, Day BW. Characterization of inhibitors of glucocorticoid receptor nuclear translocation: a model of cytoplasmic dynein-mediated cargo transport. Assay and Drug Development Technologies. 10: 46-60. PMID 21919741 DOI: 10.1089/adt.2010.0367  0.64
2011 Graf N, Ang WH, Zhu G, Myint M, Lippard SJ. Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity. Chembiochem : a European Journal of Chemical Biology. 12: 1115-23. PMID 21452186 DOI: 10.1002/cbic.201000724  0.64
2010 Zhu G, Chang P, Lippard SJ. Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1. Biochemistry. 49: 6177-83. PMID 20550106 DOI: 10.1021/bi100775t  0.64
2010 Wang D, Zhu G, Huang X, Lippard SJ. X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proceedings of the National Academy of Sciences of the United States of America. 107: 9584-9. PMID 20448203 DOI: 10.1073/pnas.1002565107  0.64
2009 Vogt A, McPherson PA, Shen X, Balachandran R, Zhu G, Raccor BS, Nelson SG, Tsang M, Day BW. High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chemical Biology & Drug Design. 74: 358-68. PMID 19691472 DOI: 10.1111/j.1747-0285.2009.00866.x  0.64
2009 Zhu G, Lippard SJ. Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links. Biochemistry. 48: 4916-25. PMID 19364127 DOI: 10.1021/bi900389b  0.64
2008 Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation. Bioorganic & Medicinal Chemistry. 16: 3291-301. PMID 18164205 DOI: 10.1016/j.bmc.2007.12.014  0.64
2007 Wang Z, McPherson PA, Raccor BS, Balachandran R, Zhu G, Day BW, Vogt A, Wipf P. Structure-activity and high-content imaging analyses of novel tubulysins. Chemical Biology & Drug Design. 70: 75-86. PMID 17683369 DOI: 10.1111/j.1747-0285.2007.00541.x  0.64
2006 Zhu G, Yang F, Balachandran R, Höök P, Vallee RB, Curran DP, Day BW. Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors. Journal of Medicinal Chemistry. 49: 2063-76. PMID 16539395 DOI: 10.1021/jm051030l  0.64
2005 Madiraju C, Edler MC, Hamel E, Raccor BS, Balachandran R, Zhu G, Giuliano KA, Vogt A, Shin Y, Fournier JH, Fukui Y, Brückner AM, Curran DP, Day BW. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry. 44: 15053-63. PMID 16274252 DOI: 10.1021/bi050685l  0.64
2005 Shin Y, Fournier JH, Balachandran R, Madiraju C, Raccor BS, Zhu G, Edler MC, Hamel E, Day BW, Curran DP. Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin. Organic Letters. 7: 2873-6. PMID 15987158 DOI: 10.1002/chin.200546209  0.64
2005 Janjic JM, Mu Y, Kendall C, Stephenson CR, Balachandran R, Raccor BS, Lu Y, Zhu G, Xie W, Wipf P, Day BW. New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides. Bioorganic & Medicinal Chemistry. 13: 157-64. PMID 15582460 DOI: 10.1016/j.bmc.2004.09.048  0.64
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