Beate Koksch, Ph.D. - Publications

Affiliations: 
Institut fur Chemie Freie Universität Berlin, Berlin, Germany 

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hohmann T, Dubatouka P, Pfeifer K, Koksch B. Establishing Fluorine-Containing Amino Acids as an Orthogonal Tool in Coiled Coil Assembly. Biomacromolecules. 24: 3357-3369. PMID 37379337 DOI: 10.1021/acs.biomac.3c00427  0.352
2023 Hohmann T, Chowdhary S, Ataka K, Er J, Dreyhsig GH, Heberle J, Koksch B. Introducing Aliphatic Fluoropeptides: Perspectives on Folding Properties, Membrane Partition and Proteolytic Stability. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36722398 DOI: 10.1002/chem.202203860  0.356
2022 Chowdhary S, Schmidt RF, Sahoo AK, Tom Dieck T, Hohmann T, Schade B, Brademann-Jock K, Thünemann AF, Netz RR, Gradzielski M, Koksch B. Rational design of amphiphilic fluorinated peptides: evaluation of self-assembly properties and hydrogel formation. Nanoscale. PMID 35796261 DOI: 10.1039/d2nr01648f  0.326
2022 Leppkes J, Dimos N, Loll B, Hohmann T, Dyrks M, Wieseke A, Keller BG, Koksch B. Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chemical Biology. 3: 773-782. PMID 35755190 DOI: 10.1039/d2cb00018k  0.336
2020 Chowdhary S, Moschner J, Mikolajczak DJ, Becker M, Thünemann AF, Kästner C, Klemczak D, Stegemann AK, Böttcher C, Metrangolo P, Netz RR, Koksch B. The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation. Chembiochem : a European Journal of Chemical Biology. 21: 3544-3554. PMID 33405360 DOI: 10.1002/Cbic.202000373  0.368
2020 Mikolajczak DJ, Berger AA, Koksch B. Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes. Angewandte Chemie (International Ed. in English). PMID 31905254 DOI: 10.1002/Anie.201908625  0.358
2020 Leppkes J, Hohmann T, Koksch B. Improved enantioselective gram scale synthesis route to N-Fmoc-protected monofluoroethylglycine Journal of Fluorine Chemistry. 232: 109453. DOI: 10.1016/J.Jfluchem.2020.109453  0.437
2020 Koksch B, Seeberger PH. Peptide Engineering Meeting 8 Peptide Science. 112. DOI: 10.1002/Pep2.24146  0.346
2019 Zivkovic I, Moschner J, Koksch B, Gruic-Sovulj I. Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic α-aminobutyrate and its fluorinated analogues. The Febs Journal. PMID 31486189 DOI: 10.1111/Febs.15053  0.336
2019 Moschner J, Stulberg V, Fernandes R, Huhmann S, Leppkes J, Koksch B. Approaches to Obtaining Fluorinated α-Amino Acids. Chemical Reviews. PMID 31436087 DOI: 10.1021/Acs.Chemrev.9B00024  0.356
2019 López-García P, Goktas M, Bergues-Pupo AE, Koksch B, Varón Silva D, Blank KG. Structural determinants of coiled coil mechanics. Physical Chemistry Chemical Physics : Pccp. 21: 9145-9149. PMID 31016294 DOI: 10.1039/C9Cp00665F  0.33
2019 Hellmund KS, Koksch B. Self-Assembling Peptides as Extracellular Matrix Mimics to Influence Stem Cell's Fate. Frontiers in Chemistry. 7: 172. PMID 31001512 DOI: 10.3389/Fchem.2019.00172  0.339
2019 Hoffmann W, Langenhan J, Huhmann S, Moschner J, Chang R, Accorsi M, Seo J, Jörg R, Meijer G, Koksch B, Bowers MT, von Helden G, Pagel K. An Intrinsic Hydrophobicity Scale for Amino Acids and Its Application to Fluorinated Compounds. Angewandte Chemie (International Ed. in English). PMID 30958917 DOI: 10.1002/Anie.201813954  0.357
2019 Mikolajczak DJ, Koksch B. Peptide–Gold Nanoparticle Conjugates as Artificial Carbonic Anhydrase Mimics Catalysts. 9: 903. DOI: 10.3390/Catal9110903  0.333
2019 Thota CK, Berger AA, Harms B, Seidel M, Böttcher C, von Berlepsch H, Xie C, Süssmuth R, Roth C, Koksch B. Short self‐assembling cationic antimicrobial peptide mimetics based on a 3,5‐diaminobenzoic acid scaffold Peptide Science. 112. DOI: 10.1002/Pep2.24130  0.419
2018 de Freitas MS, Rezaei Araghi R, Brandenburg E, Leiterer J, Emmerling F, Folmert K, Gerling-Driessen UIM, Bardiaux B, Böttcher C, Pagel K, Diehl A, Berlepsch HV, Oschkinat H, Koksch B. The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide. Journal of Structural Biology. PMID 29857134 DOI: 10.1016/J.Jsb.2018.05.009  0.385
2018 Huhmann S, Koksch B. Fine-Tuning the Proteolytic Stability of Peptides with Fluorinated Amino Acids European Journal of Organic Chemistry. 2018: 3667-3679. DOI: 10.1002/Ejoc.201800803  0.427
2018 Mikolajczak DJ, Scholz J, Koksch B. Tuning the Catalytic Activity and Substrate Specificity of Peptide-Nanoparticle Conjugates Chemcatchem. 10: 5665-5668. DOI: 10.1002/Cctc.201801521  0.349
2017 Huhmann S, Stegemann AK, Folmert K, Klemczak D, Moschner J, Kube M, Koksch B. Position-dependent impact of hexafluoroleucine and trifluoroisoleucine on protease digestion. Beilstein Journal of Organic Chemistry. 13: 2869-2882. PMID 29564015 DOI: 10.3762/Bjoc.13.279  0.458
2017 Hoffmann W, Folmert K, Moschner J, Huang X, von Berlepsch H, Koksch B, Bowers MT, von Helden G, Pagel K. NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation. Journal of the American Chemical Society. PMID 29235867 DOI: 10.1021/Jacs.7B09510  0.336
2017 Mikolajczak DJ, Heier JL, Schade B, Koksch B. Catalytic activity of peptide-nanoparticle conjugates regulated by a conformational change. Biomacromolecules. PMID 28925256 DOI: 10.1021/Acs.Biomac.7B00887  0.414
2017 Völler JS, Thi To TM, Biava H, Koksch B, Budisa N. Global substitution of hemeproteins with noncanonical amino acids in Escherichia coli with intact cofactor maturation machinery. Enzyme and Microbial Technology. 106: 55-59. PMID 28859810 DOI: 10.1016/J.Enzmictec.2017.06.014  0.382
2017 Berger AA, Völler JS, Budisa N, Koksch B. Deciphering the Fluorine Code-The Many Hats Fluorine Wears in a Protein Environment. Accounts of Chemical Research. PMID 28803466 DOI: 10.1021/Acs.Accounts.7B00226  0.466
2017 Völler JS, Dulic M, Gerling-Driessen UI, Biava H, Baumann T, Budisa N, Gruic-Sovulj I, Koksch B. Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation. Acs Central Science. 3: 73-80. PMID 28149956 DOI: 10.1021/Acscentsci.6B00339  0.416
2017 Budisa N, Völler JS, Koksch B, Acevedo-Rocha CG, Kubyshkin V, Agostini F. Xenobiology meets enzymology: Exploring the potential of unnatural building blocks in biocatalysis. Angewandte Chemie (International Ed. in English). PMID 28085996 DOI: 10.1002/Anie.201610129  0.318
2017 Robalo JR, Huhmann S, Koksch B, Vila Verde A. The Multiple Origins of the Hydrophobicity of Fluorinated Apolar Amino Acids Chem. 3: 881-897. DOI: 10.1016/J.Chempr.2017.09.012  0.365
2016 Folmert K, Broncel M, V Berlepsch H, Ullrich CH, Siegert MA, Koksch B. Inhibition of peptide aggregation by means of enzymatic phosphorylation. Beilstein Journal of Organic Chemistry. 12: 2462-2470. PMID 28144314 DOI: 10.3762/Bjoc.12.240  0.41
2016 Heier JL, Mikolajczak DJ, Böttcher C, Koksch B. Substrate specificity of an actively assembling amyloid catalyst. Biopolymers. PMID 27858968 DOI: 10.1002/Bip.23003  0.337
2016 Hoernke M, Tassler S, Koksch B, Brezesinski G. Membrane Binding of Peptide Models for early Stages of Amyloid Formation: Lipid Packing Counts more than Charge. Chemistry and Physics of Lipids. PMID 27134131 DOI: 10.1016/J.Chemphyslip.2016.02.010  0.381
2015 Ye S, Loll B, Berger AA, Mülow U, Alings C, Wahl MC, Koksch B. Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chemical Science. 6: 5246-5254. PMID 29449928 DOI: 10.1039/C4Sc03227F  0.335
2015 Schöne D, Schade B, Böttcher C, Koksch B. Impact of multivalent charge presentation on peptide-nanoparticle aggregation. Beilstein Journal of Organic Chemistry. 11: 792-803. PMID 26124881 DOI: 10.3762/Bjoc.11.89  0.39
2015 Gerling-Driessen UI, Mujkic-Ninnemann N, Ponader D, Schöne D, Hartmann L, Koksch B. Exploiting oligo(amido amine) backbones for the multivalent presentation of coiled coil peptides. Biomacromolecules. PMID 26114337 DOI: 10.1021/Acs.Biomac.5B00634  0.408
2015 Zacco E, Hütter J, Heier JL, Mortier J, Seeberger PH, Lepenies B, Koksch B. Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting. Acs Chemical Biology. PMID 26057877 DOI: 10.1021/Acschembio.5B00435  0.409
2015 Zacco E, Anish C, Martin CE, V Berlepsch H, Brandenburg E, Seeberger PH, Koksch B. A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens. Biomacromolecules. 16: 2188-97. PMID 26017366 DOI: 10.1021/Acs.Biomac.5B00572  0.394
2015 Schubert F, Rossi M, Baldauf C, Pagel K, Warnke S, von Helden G, Filsinger F, Kupser P, Meijer G, Salwiczek M, Koksch B, Scheffler M, Blum V. Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H(+)vs. Ac-Lys-Ala19 + H(+) and the current reach of DFT. Physical Chemistry Chemical Physics : Pccp. 17: 7373-85. PMID 25700010 DOI: 10.1039/C4Cp05541A  0.377
2015 Mortier J, Nyakatura EK, Reimann O, Huhmann S, Daldrop JO, Baldauf C, Wolber G, Miettinen MS, Koksch B. Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics. Journal of Chemical Information and Modeling. 55: 495-500. PMID 25648076 DOI: 10.1021/Ci500689C  0.371
2015 Schubert F, Pagel K, Rossi M, Warnke S, Salwiczek M, Koksch B, von Helden G, Blum V, Baldauf C, Scheffler M. Native like helices in a specially designed β peptide in the gas phase. Physical Chemistry Chemical Physics : Pccp. 17: 5376-85. PMID 25611682 DOI: 10.1039/C4Cp05216A  0.416
2015 Gerling UI, Miettinen MS, Koksch B. Concluding the amyloid formation pathway of a coiled-coil-based peptide from the size of the critical nucleus. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 16: 108-14. PMID 25257178 DOI: 10.1002/Cphc.201402400  0.354
2015 Huhmann S, Nyakatura EK, Erdbrink H, Gerling UIM, Czekelius C, Koksch B. Effects of single substitutions with hexafluoroleucine and trifluorovaline on the hydrophobic core formation of a heterodimeric coiled coil Journal of Fluorine Chemistry. 175: 32-35. DOI: 10.1016/J.Jfluchem.2015.03.003  0.487
2015 Vukelic S, Ushakov DB, Gilmore K, Koksch B, Seeberger PH. Flow synthesis of fluorinated α-amino acids European Journal of Organic Chemistry. 2015: 3036-3039. DOI: 10.1002/Ejoc.201500300  0.36
2014 Nyakatura EK, Mortier J, Radtke VS, Wieczorek S, Rezaei Araghi R, Baldauf C, Wolber G, Koksch B. β- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils. Acs Medicinal Chemistry Letters. 5: 1300-3. PMID 25516788 DOI: 10.1021/Ml500361C  0.478
2014 Asante V, Mortier J, Wolber G, Koksch B. Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin. Amino Acids. 46: 2733-44. PMID 25193166 DOI: 10.1007/S00726-014-1819-7  0.456
2014 Mortier J, Nyakatura EK, Miettinen M, Baldauf C, Wolber G, Koksch B. Balancing selectivity vs stability using molecular dynamics and umbrella sampling. Journal of Cheminformatics. 6: O22. PMID 24765121 DOI: 10.1186/1758-2946-6-S1-O22  0.415
2014 Nyakatura EK, Rezaei Araghi R, Mortier J, Wieczorek S, Baldauf C, Wolber G, Koksch B. An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides. Acs Chemical Biology. 9: 613-6. PMID 24341921 DOI: 10.1021/Cb4007979  0.453
2014 Maity J, Gerling UI, Vukeli? S, Schäfer A, Koksch B. Proline-glutamate chimera's side chain conformation directs the type of β-hairpin structure. Amino Acids. 46: 177-86. PMID 24221353 DOI: 10.1007/S00726-013-1610-1  0.384
2014 Gerling UIM, Salwiczek M, Cadicamo CD, Erdbrink H, Czekelius C, Grage SL, Wadhwani P, Ulrich AS, Behrends M, Haufe G, Koksch B. Fluorinated amino acids in amyloid formation: A symphony of size, hydrophobicity and α-helix propensity Chemical Science. 5: 819-830. DOI: 10.1039/C3Sc52932K  0.467
2014 Baldauf C, Schubert F, Pagel K, Warnke S, Rossi M, Salwiczek M, Koksch B, von Helden G, Blum V. Is there a Beta-Peptide Equivalent of the Alpha-Helix? Biophysical Journal. 106: 654a. DOI: 10.1016/J.Bpj.2013.11.3621  0.418
2014 Do N, Weindl G, Fleige E, Salwiczek M, Koksch B, Haag R, Schäfer-Korting M. Core-multishell nanotransporters enhance skin penetration of the cell-penetrating peptide low molecular weight protamine Polymers For Advanced Technologies. 25: 1337-1341. DOI: 10.1002/Pat.3362  0.342
2013 Erdbrink H, Nyakatura EK, Huhmann S, Gerling UI, Lentz D, Koksch B, Czekelius C. Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine. Beilstein Journal of Organic Chemistry. 9: 2009-14. PMID 24204411 DOI: 10.3762/Bjoc.9.236  0.318
2013 Baldauf C, Pagel K, Warnke S, von Helden G, Koksch B, Blum V, Scheffler M. How cations change peptide structure. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 11224-34. PMID 23853047 DOI: 10.1002/Chem.201204554  0.414
2013 Rakowska PD, Jiang H, Ray S, Pyne A, Lamarre B, Carr M, Judge PJ, Ravi J, Gerling UI, Koksch B, Martyna GJ, Hoogenboom BW, Watts A, Crain J, Grovenor CR, et al. Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers. Proceedings of the National Academy of Sciences of the United States of America. 110: 8918-23. PMID 23671080 DOI: 10.1073/Pnas.1222824110  0.351
2013 Asante V, Mortier J, Schlüter H, Koksch B. Impact of fluorination on proteolytic stability of peptides in human blood plasma. Bioorganic & Medicinal Chemistry. 21: 3542-6. PMID 23623671 DOI: 10.1016/J.Bmc.2013.03.051  0.419
2013 Cadicamo CD, Mortier J, Wolber G, Hell M, Heinrich IE, Michel D, Semlin L, Berger U, Korting HC, Höltje HD, Koksch B, Borelli C. Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans. Biochemical Pharmacology. 85: 881-7. PMID 23262278 DOI: 10.1016/J.Bcp.2012.12.008  0.316
2013 Nyakatura EK, Reimann O, Vagt T, Salwiczek M, Koksch B. Accommodating fluorinated amino acids in a helical peptide environment Rsc Advances. 3: 6319-6322. DOI: 10.1039/C3Ra41110A  0.457
2012 Erdbrink H, Peuser I, Gerling UI, Lentz D, Koksch B, Czekelius C. Conjugate hydrotrifluoromethylation of α,β-unsaturated acyl-oxazolidinones: synthesis of chiral fluorinated amino acids. Organic & Biomolecular Chemistry. 10: 8583-6. PMID 23042408 DOI: 10.1039/C2Ob26810H  0.357
2012 Brandenburg E, Berlepsch HV, Leiterer J, Emmerling F, Koksch B. Formation of α-helical nanofibers by mixing β-structured and α-helical coiled coil peptides. Biomacromolecules. 13: 3542-51. PMID 22946440 DOI: 10.1021/Bm300882D  0.433
2012 Rezaei Araghi R, Mahrenholz CC, Volkmer R, Koksch B. Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique. Beilstein Journal of Organic Chemistry. 8: 640-9. PMID 22563362 DOI: 10.3762/Bjoc.8.71  0.437
2012 Salwiczek M, Nyakatura EK, Gerling UI, Ye S, Koksch B. Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions. Chemical Society Reviews. 41: 2135-71. PMID 22130572 DOI: 10.1039/C1Cs15241F  0.462
2012 Brandenburg E, von Berlepsch H, Koksch B. Specific in situ discrimination of amyloid fibrils versus α-helical fibres by the fluorophore NIAD-4. Molecular Biosystems. 8: 557-64. PMID 22116468 DOI: 10.1039/C1Mb05370A  0.371
2012 Maity J, Saha P, Gerling U, Lentz D, Koksch B. An Approach for Simultaneous Synthesis of cis- and trans-3-Substituted Proline-Glutamic Acid Chimeras Synthesis. 44. DOI: 10.1055/S-0032-1316986  0.356
2012 Baldauf C, Pagel K, Warnke S, von Helden G, Meijer G, Koksch B, Blum V, Scheffler M. Local Conformational Preferences of Peptides Near Attached Cations: Structure Determination by First-Principles Theory and IR-Spectroscopy Biophysical Journal. 102: 46a. DOI: 10.1016/J.Bpj.2011.11.280  0.368
2012 Hoernke M, Koksch B, Brezesinski G. The Conformation of Amyloidogenic Peptides is Governed by (Transient) Interfaces and Influenced by Metal Ion Complexation Biophysical Journal. 102: 489a. DOI: 10.1016/J.Bpj.2011.11.2679  0.378
2011 Hoernke M, Falenski JA, Schwieger C, Koksch B, Brezesinski G. Triggers for β-sheet formation at the hydrophobic-hydrophilic interface: high concentration, in-plane orientational order, and metal ion complexation. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 14218-31. PMID 22011020 DOI: 10.1021/La203016Z  0.386
2011 Brandenburg E, von Berlepsch H, Gerling UI, Böttcher C, Koksch B. Inhibition of amyloid aggregation by formation of helical assemblies. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 10651-61. PMID 22003512 DOI: 10.1002/Chem.201100670  0.402
2011 Hoernke M, Koksch B, Brezesinski G. Amyloidogenic peptides at hydrophobic-hydrophilic interfaces: coordination affinities and the chelate effect dictate the competitive binding of Cu2+ and Zn2+. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 12: 2225-9. PMID 21751332 DOI: 10.1002/Cphc.201100215  0.339
2011 Gerling UI, Brandenburg E, von Berlepsch H, Pagel K, Koksch B. Structure analysis of an amyloid-forming model peptide by a systematic glycine and proline scan. Biomacromolecules. 12: 2988-96. PMID 21726080 DOI: 10.1021/Bm200587M  0.455
2011 Rezaei Araghi R, Baldauf C, Gerling UI, Cadicamo CD, Koksch B. A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β- and γ-amino acids. Amino Acids. 41: 733-42. PMID 21638022 DOI: 10.1007/S00726-011-0941-Z  0.456
2011 Araghi RR, Koksch B. A helix-forming αβγ-chimeric peptide with catalytic activity: a hybrid peptide ligase. Chemical Communications (Cambridge, England). 47: 3544-6. PMID 21327202 DOI: 10.1039/C0Cc03760E  0.437
2011 Botev A, Munter LM, Wenzel R, Richter L, Althoff V, Ismer J, Gerling U, Weise C, Koksch B, Hildebrand PW, Bittl R, Multhaup G. The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators. Biochemistry. 50: 828-35. PMID 21186781 DOI: 10.1021/Bi1014002  0.363
2010 Wagner SC, Roskamp M, Pallerla M, Araghi RR, Schlecht S, Koksch B. Nanoparticle-induced folding and fibril formation of coiled-coil-based model peptides. Small (Weinheim An Der Bergstrasse, Germany). 6: 1321-8. PMID 20517875 DOI: 10.1002/Smll.200902067  0.426
2010 Falenski JA, Gerling UI, Koksch B. Multiple glycosylation of de novo designed alpha-helical coiled coil peptides. Bioorganic & Medicinal Chemistry. 18: 3703-6. PMID 20513637 DOI: 10.1016/J.Bmc.2010.03.061  0.404
2010 Ye S, Ann Berger A, Petzold D, Reimann O, Matt B, Koksch B. Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis. Beilstein Journal of Organic Chemistry. 6: 40. PMID 20502658 DOI: 10.3762/Bjoc.6.40  0.396
2010 Broncel M, Falenski JA, Wagner SC, Hackenberger CP, Koksch B. How post-translational modifications influence amyloid formation: a systematic study of phosphorylation and glycosylation in model peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 7881-8. PMID 20491120 DOI: 10.1002/Chem.200902452  0.394
2010 Broncel M, Wagner SC, Paul K, Hackenberger CP, Koksch B. Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides. Organic & Biomolecular Chemistry. 8: 2575-9. PMID 20485793 DOI: 10.1039/C001458C  0.407
2010 Broncel M, Wagner SC, Hackenberger CP, Koksch B. Enzymatically triggered amyloid formation: an approach for studying peptide aggregation. Chemical Communications (Cambridge, England). 46: 3080-2. PMID 20424744 DOI: 10.1039/C001460E  0.398
2010 Salwiczek M, Mikhailiuk PK, Afonin S, Komarov IV, Ulrich AS, Koksch B. Compatibility of the conformationally rigid CF3-Bpg side chain with the hydrophobic coiled-coil interface. Amino Acids. 39: 1589-93. PMID 20386938 DOI: 10.1007/S00726-010-0581-8  0.362
2010 von Berlepsch H, Brandenburg E, Koksch B, Böttcher C. Peptide adsorption to cyanine dye aggregates revealed by cryo-transmission electron microscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 11452-60. PMID 20364866 DOI: 10.1021/La100944D  0.41
2010 Hoernke M, Koksch B, Brezesinski G. Influence of the hydrophobic interface and transition metal ions on the conformation of amyloidogenic model peptides. Biophysical Chemistry. 150: 64-72. PMID 20347516 DOI: 10.1016/J.Bpc.2010.02.014  0.4
2010 Vagt T, Nyakatura E, Salwiczek M, Jäckel C, Koksch B. Towards identifying preferred interaction partners of fluorinated amino acids within the hydrophobic environment of a dimeric coiled coil peptide. Organic & Biomolecular Chemistry. 8: 1382-6. PMID 20204211 DOI: 10.1039/B917205J  0.455
2009 Weimann DP, Winkler HD, Falenski JA, Koksch B, Schalley CA. Highly dynamic motion of crown ethers along oligolysine peptide chains. Nature Chemistry. 1: 573-7. PMID 21378938 DOI: 10.1038/Nchem.352  0.385
2009 Samsonov SA, Salwiczek M, Anders G, Koksch B, Pisabarro MT. Fluorine in protein environments: a QM and MD study. The Journal of Physical Chemistry. B. 113: 16400-8. PMID 19947631 DOI: 10.1021/Jp906402B  0.397
2009 Becaud J, Mu L, Karramkam M, Schubiger PA, Ametamey SM, Graham K, Stellfeld T, Lehmann L, Borkowski S, Berndorff D, Dinkelborg L, Srinivasan A, Smits R, Koksch B. Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution. Bioconjugate Chemistry. 20: 2254-61. PMID 19921791 DOI: 10.1021/Bc900240Z  0.301
2009 Salwiczek M, Samsonov S, Vagt T, Nyakatura E, Fleige E, Numata J, Cölfen H, Pisabarro MT, Koksch B. Position-dependent effects of fluorinated amino acids on the hydrophobic core formation of a heterodimeric coiled coil. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 7628-36. PMID 19579235 DOI: 10.1002/Chem.200802136  0.433
2009 Vagt T, Jäckel C, Samsonov S, Teresa Pisabarro M, Koksch B. Selection of a buried salt bridge by phage display. Bioorganic & Medicinal Chemistry Letters. 19: 3924-7. PMID 19369078 DOI: 10.1016/J.Bmcl.2009.03.062  0.433
2009 Wagner SC, Roskamp M, Cölfen H, Böttcher C, Schlecht S, Koksch B. Switchable electrostatic interactions between gold nanoparticles and coiled coil peptides direct colloid assembly. Organic & Biomolecular Chemistry. 7: 46-51. PMID 19081944 DOI: 10.1039/B813429D  0.365
2009 Weimann DP, Winkler HDF, Falenski JA, Koksch B, Schalley CA. Erratum: Highly dynamic motion of crown ethers along oligolysine peptide chains Nature Chemistry. 1: 668-668. DOI: 10.1038/Nchem.431  0.322
2009 Pagel K, Kupser P, Bierau F, Polfer NC, Steill JD, Oomens J, Meijer G, Koksch B, von Helden G. Gas-phase IR spectra of intact α-helical coiled coil protein complexes International Journal of Mass Spectrometry. 283: 161-168. DOI: 10.1016/J.Ijms.2009.02.026  0.403
2008 Pagel K, Wagner SC, Rezaei Araghi R, von Berlepsch H, Böttcher C, Koksch B. Intramolecular charge interactions as a tool to control the coiled-coil-to-amyloid transformation. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 11442-51. PMID 19016556 DOI: 10.1002/Chem.200801206  0.421
2008 Pagel K, Koksch B. Following polypeptide folding and assembly with conformational switches. Current Opinion in Chemical Biology. 12: 730-9. PMID 18840544 DOI: 10.1016/J.Cbpa.2008.09.005  0.388
2008 Smits R, Cadicamo CD, Burger K, Koksch B. Synthetic strategies to alpha-trifluoromethyl and alpha-difluoromethyl substituted alpha-amino acids. Chemical Society Reviews. 37: 1727-39. PMID 18648692 DOI: 10.1039/B800310F  0.346
2008 Pagel K, Seri T, von Berlepsch H, Griebel J, Kirmse R, Böttcher C, Koksch B. How metal ions affect amyloid formation: Cu2+- and Zn2+-sensitive peptides. Chembiochem : a European Journal of Chemical Biology. 9: 531-6. PMID 18232039 DOI: 10.1002/Cbic.200700656  0.403
2007 Spengler J, Koksch B, Albericio F. Simple machine-assisted protocol for solid-phase synthesis of depsipeptides. Biopolymers. 88: 823-8. PMID 17922494 DOI: 10.1002/Bip.20858  0.311
2007 Jaeckel C, Koksch B. The Potential of Fluorine for Peptide and Protein Modification Cheminform. 38. DOI: 10.1002/chin.200720241  0.316
2007 Hakelberg M, Koksch B. Fluorine in Peptides: Coiled coil model systems as tools to evaluate the influence of fluorinated amino acids on structure and stability of peptides Chimica Oggi. 25: 48-53.  0.323
2006 Smits R, Koksch B. How C(alpha)-Fluoroalkyl amino acids and peptides interact with enzymes: studies concerning the influence on proteolytic stability, enzymatic resolution and peptide coupling. Current Topics in Medicinal Chemistry. 6: 1483-98. PMID 16918464 DOI: 10.2174/156802606777951055  0.463
2006 Burger K, Hennig L, Tsouker P, Spengler J, Albericio F, Koksch B. Synthesis of alpha-trifluoromethyl alpha-amino acids with aromatic, heteroaromatic and ferrocenyl subunits in the side chain. Amino Acids. 31: 55-62. PMID 16715413 DOI: 10.1007/S00726-006-0322-1  0.321
2006 Vagt T, Zschörnig O, Huster D, Koksch B. Membrane binding and structure of de novo designed alpha-helical cationic coiled-coil-forming peptides. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 7: 1361-71. PMID 16680794 DOI: 10.1002/Cphc.200600010  0.421
2006 Pagel K, Wagner SC, Samedov K, von Berlepsch H, Böttcher C, Koksch B. Random coils, beta-sheet ribbons, and alpha-helical fibers: one peptide adopting three different secondary structures at will. Journal of the American Chemical Society. 128: 2196-7. PMID 16478157 DOI: 10.1021/Ja057450H  0.411
2005 Pagel K, Vagt T, Koksch B. Directing the secondary structure of polypeptides at will: from helices to amyloids and back again? Organic & Biomolecular Chemistry. 3: 3843-50. PMID 16239998 DOI: 10.1039/B510098D  0.406
2005 Piñeiro A, Villa A, Vagt T, Koksch B, Mark AE. A molecular dynamics study of the formation, stability, and oligomerization state of two designed coiled coils: possibilities and limitations. Biophysical Journal. 89: 3701-13. PMID 16150975 DOI: 10.1529/Biophysj.104.055590  0.369
2005 Dreier B, Fuller RP, Segal DJ, Lund CV, Blancafort P, Huber A, Koksch B, Barbas CF. Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors. The Journal of Biological Chemistry. 280: 35588-97. PMID 16107335 DOI: 10.1074/jbc.M506654200  0.695
2005 Pagel K, Vagt T, Kohajda T, Koksch B. From alpha-helix to beta-sheet--a reversible metal ion induced peptide secondary structure switch. Organic & Biomolecular Chemistry. 3: 2500-2. PMID 15999178 DOI: 10.1039/B505979H  0.385
2005 Pagel K, Seeger K, Seiwert B, Villa A, Mark AE, Berger S, Koksch B. Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide. Organic & Biomolecular Chemistry. 3: 1189-94. PMID 15785806 DOI: 10.1039/B418167K  0.411
2005 Jäckel C, Koksch B. Cover Picture: Fluorine in Peptide Design and Protein Engineering (Eur. J. Org. Chem. 21/2005) European Journal of Organic Chemistry. 2005: 4471-4471. DOI: 10.1002/Ejoc.200590042  0.487
2005 Jäckel C, Koksch B. Fluorine in peptide design and protein engineering European Journal of Organic Chemistry. 4483-4503. DOI: 10.1002/Ejoc.200500205  0.443
2004 Jäckel C, Seufert W, Thust S, Koksch B. Evaluation of the molecular interactions of fluorinated amino acids with native polypeptides. Chembiochem : a European Journal of Chemical Biology. 5: 717-20. PMID 15122644 DOI: 10.1002/Cbic.200300840  0.34
2004 Koksch B, Dahl C, Radics G, Vocks A, Arnold K, Arnhold J, Sieler J, Burger K. Fluoro-modified chemotactic peptides: fMLF analogues. Journal of Peptide Science : An Official Publication of the European Peptide Society. 10: 67-81. PMID 14994985 DOI: 10.1002/Psc.515  0.41
2004 Osipov SN, Lange T, Tsouker P, Spengler J, Hennig L, Koksch B, Berger S, El-Kousy SM, Burger K. Hexafluoroacetone as a protecting and activating reagent: Synthesis of new types of fluoro-substituted α-amino, α-hydroxy and α-mercapto acids Synthesis. 1821-1829. DOI: 10.1055/S-2004-829131  0.38
2004 Thust S, Koksch B. Discovery of carboxypeptidase Y as a catalyst for the incorporation of sterically demanding α-fluoroalkyl amino acids into peptides Tetrahedron Letters. 45: 1163-1165. DOI: 10.1016/J.Tetlet.2003.12.007  0.377
2004 Koksch B, Quaedflieg PJLM, Michel T, Burger K, Broxterman QB, Schoemaker HE. Enzymatic resolution of Cα-fluoroalkyl substituted amino acids Tetrahedron Asymmetry. 15: 1401-1407. DOI: 10.1016/J.Tetasy.2004.02.027  0.325
2003 Thust S, Koksch B. Protease-catalyzed peptide synthesis for the site-specific incorporation of alpha-fluoroalkyl amino acids into peptides. The Journal of Organic Chemistry. 68: 2290-6. PMID 12636393 DOI: 10.1021/Jo020613P  0.411
2003 Segal DJ, Beerli RR, Blancafort P, Dreier B, Effertz K, Huber A, Koksch B, Lund CV, Magnenat L, Valente D, Barbas CF. Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins. Biochemistry. 42: 2137-48. PMID 12590603 DOI: 10.1021/Bi026806O  0.7
2003 Radics G, Koksch B, El-Kousy SM, Spengler J, Burger K. L-α-Methylhomoisoserine: A New Versatile Building Block for Peptide and Depsipeptide Modification Synlett. 1826-1829. DOI: 10.1055/S-2003-41477  0.362
2002 Michel T, Koksch B, Osipov SN, Golubev AS, Sieler J, Burger K. Peptide synthesis with α-(difluoromethyl)-substituted α-amino acids Collection of Czechoslovak Chemical Communications. 67: 1533-1559. DOI: 10.1002/CHIN.200312177  0.379
2000 Koksch B, Mütze K, Osipov SN, Golubev AS, Burger K. Synthesis of highly fluorinated dipeptide building blocks Tetrahedron Letters. 41: 3825-3828. DOI: 10.1016/S0040-4039(00)00540-2  0.339
1999 Burger K, Kluge M, Fehn S, Koksch B, Hennig L, Müller G. A New Approach to Glycopeptides. Angewandte Chemie (International Ed. in English). 38: 1414-1416. PMID 29711583 DOI: 10.1002/(Sici)1521-3773(19990517)38:10<1414::Aid-Anie1414>3.0.Co;2-L  0.309
1999 Bordusa F, Dahl C, Jakubke HD, Burger K, Koksch B. Synthesis of α-fluoroalkyl substituted peptides via enzymatic fragment condensation Tetrahedron Asymmetry. 10: 307-313. DOI: 10.1016/S0957-4166(98)00508-4  0.428
1998 Burger K, Mütze K, Hollweck W, Koksch B. Incorporation of α-trifluoromethyl substituted α-amino acids into C- and N-terminal position of peptides and peptide mimetics using multicomponent reactions Tetrahedron. 54: 5915-5928. DOI: 10.1016/S0040-4020(98)00291-9  0.431
1998 Koksch B, Sewald N. Modifizierung von Peptiden Nachrichten Aus Chemie, Technik Und Laboratorium. 46: 27-30. DOI: 10.1002/Nadc.19980460113  0.346
1997 Koksch B, Sewald N, Hofmann HJ, Burger K, Jakubke HD. Proteolytically stable peptides by incorporation of alpha-Tfm amino acids. Journal of Peptide Science : An Official Publication of the European Peptide Society. 3: 157-67. PMID 9230481 DOI: 10.1002/(SICI)1099-1387(199705)3:3<157::AID-PSC94>3.0.CO;2-W  0.315
1997 Koksch B, Sewald N, Hofmann H, Burger K, Jakubke H. Proteolytically stable peptides by incorporation of α-Tfm amino acids Journal of Peptide Science. 3: 157-167. DOI: 10.1002/(Sici)1099-1387(199705)3:3<157::Aid-Psc94>3.0.Co;2-W  0.453
1997 Koksch B, Jakubke HD, Hofmann HJ, Gussmann M, Burger K. Influence of α-fluoralkyl substituted amino acids on secondary structure and properties of peptides Amino Acids. 13: 73.  0.329
1996 Koksch B, Sewald N, Burger K, Jakubke HD. Peptide modification by incorporation ofα-trifluoromethyl substituted amino acids. Amino Acids. 11: 425-34. PMID 24178726 DOI: 10.1007/Bf00807946  0.43
1996 Koksch B, Sewald N, Burger K, Jakubke HD. Peptide modification by incorporation of α-trifluoromethyl substituted amino acids Amino Acids. 11: 425-434.  0.334
1996 Koksch B, Sewald N, Jakubke HD, Burger K. Synthesis and Incorporation of α-Trifluoromethyl-Substituted Amino Acids into Peptides Acs Symposium Series. 639: 42-58.  0.327
1995 Sewald N, Hollweck W, Mütze K, Schierlinger C, Seymour LC, Gaa K, Burger K, Koksch B, Jakubke HD. Peptide modification by introduction ofα-trifluoromethyl substituted amino acids. Amino Acids. 8: 187-94. PMID 24186327 DOI: 10.1007/Bf00806491  0.436
1994 Burger K, Schierlinger C, Mütze K, Hollweck W, Koksch B. 2-Trifluormethyl-substituierte Aminosäuren, 20. N- und C-terminaler Einbau von α-Trifluormethyl-substituierten α-Aminosäuren in Azapeptide Liebigs Annalen Der Chemie. 1994: 407-413. DOI: 10.1002/Jlac.199419940414  0.327
1993 Burger K, M�tze K, Hollweck W, Koksch B, Kuhl P, Jakubke H, Riede J, Schier A. Untersuchungen zur proteasekatalysierten und chemischen Peptidbindungskn�pfung mit ?-trifluormethylsubstituierten ?-Aminos�uren Journal F�R Praktische Chemie/Chemiker-Zeitung. 335: 321-331. DOI: 10.1002/Prac.19933350404  0.379
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