Year |
Citation |
Score |
2019 |
McBrayer D, Schoonover M, Long KJ, Escobedo R, Kerwin SM. N-Methylmesoporphyrin IX Exhibits G-quadruplex Specific Photocleavage Activity. Chembiochem : a European Journal of Chemical Biology. PMID 30850998 DOI: 10.1002/Cbic.201900002 |
0.812 |
|
2019 |
Reinus B, Kerwin SM. Preparation and Utility of -Alkynyl Azoles in Synthesis. Molecules (Basel, Switzerland). 24. PMID 30682796 DOI: 10.3390/Molecules24030422 |
0.327 |
|
2019 |
Reinus BJ, Kerwin SM. N-Alkynyl Pyrrole Based Total Synthesis of Shensongine A Synthesis. 51: 4085-4105. DOI: 10.1055/S-0037-1611904 |
0.331 |
|
2017 |
Del Mundo IM, Zewail-Foote M, Kerwin SM, Vasquez KM. Alternative DNA structure formation in the mutagenic human c-MYC promoter. Nucleic Acids Research. PMID 28334873 DOI: 10.1093/Nar/Gkx100 |
0.496 |
|
2017 |
Reinus B, Kerwin S. A Copper-Catalyzed N-Alkynylation Route to 2-Substituted N-Alkynyl Pyrroles and Their Cyclization into Pyrrolo[2,1-c]oxazin-1-ones: A Formal Total Synthesis of Peramine Synthesis. 49: 2544-2554. DOI: 10.1055/S-0036-1588736 |
0.35 |
|
2015 |
McBrayer D, Kerwin SM. Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage. Molecules (Basel, Switzerland). 20: 16446-65. PMID 26378509 DOI: 10.3390/Molecules200916446 |
0.821 |
|
2015 |
Kerwin SM, David WM. G-quadruplex dynamics: Assays for intramolecular G-quadruplex helicases and inhibitors Biological Relevance and Therapeutic Applications of Dna and Rna Quadruplexes. 85-99. DOI: 10.4155/fseb12013.14.66 |
0.734 |
|
2014 |
Kerwin SM, Cha J. A concise synthesis of rooperol and related 1,5-diarylpent-1-en-4-ynes Tetrahedron Letters. 55: 137-141. DOI: 10.1016/J.Tetlet.2013.10.138 |
0.31 |
|
2012 |
Schoonover M, Kerwin SM. G-quadruplex DNA cleavage preference and identification of a perylene diimide G-quadruplex photocleavage agent using a rapid fluorescent assay Bioorganic and Medicinal Chemistry. 20: 6904-6918. PMID 23159040 DOI: 10.1016/J.Bmc.2012.10.017 |
0.341 |
|
2012 |
Schoonover M, Kerwin SM. G-quadruplex DNA cleavage preference and identification of a perylene diimide G-quadruplex photocleavage agent using a rapid fluorescent assay Bioorganic and Medicinal Chemistry. 20: 6904-6918. PMID 23159040 DOI: 10.1016/J.Bmc.2012.10.017 |
0.341 |
|
2011 |
Laroche C, Li J, Kerwin SM. Cytotoxic 1,2-dialkynylimidazole-based aza-enediynes: Aza-Bergman rearrangement rates do not predict cytotoxicity Journal of Medicinal Chemistry. 54: 5059-5069. PMID 21667990 DOI: 10.1021/Jm200289J |
0.391 |
|
2011 |
Schoonover M, Kerwin SM. A fluorescence-based G-quadruplex DNA cleavage assay Acs Symposium Series. 1082: 13-32. DOI: 10.1021/bk-2011-1082.ch002 |
0.339 |
|
2011 |
Schoonover M, Kerwin SM. A fluorescence-based G-quadruplex DNA cleavage assay Acs Symposium Series. 1082: 13-32. DOI: 10.1021/bk-2011-1082.ch002 |
0.339 |
|
2010 |
Laroche C, Li J, Gonzales C, David WM, Kerwin SM. Cyclization kinetics and biological evaluation of an anticancer 1,2-dialkynylimidazole Organic and Biomolecular Chemistry. 8: 1535-1539. PMID 20237664 DOI: 10.1039/B925261D |
0.76 |
|
2010 |
Kumar D, David WM, Kerwin SM. ChemInform Abstract: N-Propargyl-2-alkynylbenzothiazolium Aza-enediynes: Role of the 2-Alkynylbenzothiazolium Functionality in DNA Cleavage. Cheminform. 33: no-no. DOI: 10.1002/chin.200209134 |
0.764 |
|
2009 |
Laroche C, Kerwin SM. Efficient, regioselective access to bicyclic imidazo[1,2-x]- heterocycles via gold- and base-promoted cyclization of 1-alkynylimidazoles Journal of Organic Chemistry. 74: 9229-9232. PMID 19950886 DOI: 10.1021/Jo902073M |
0.324 |
|
2009 |
Marriner GA, Kerwin SM. An improved synthesis of (±)-N#-nitrosonornicotine 5#-acetate Journal of Organic Chemistry. 74: 2891-2892. PMID 19271724 DOI: 10.1021/Jo9000417 |
0.313 |
|
2009 |
Plyler J, Jasheway K, Tuesuwan B, Karr J, Brennan JS, Kerwin SM, David WM. Real-time investigation of SV40 large T-antigen helicase activity using surface plasmon resonance. Cell Biochemistry and Biophysics. 53: 43-52. PMID 19048412 DOI: 10.1007/S12013-008-9038-Z |
0.792 |
|
2009 |
Plyler J, Jasheway K, Tuesuwan B, Karr J, Brennan JS, Kerwin SM, David WM. Real-time investigation of SV40 large T-antigen helicase activity using surface plasmon resonance. Cell Biochemistry and Biophysics. 53: 43-52. PMID 19048412 DOI: 10.1007/S12013-008-9038-Z |
0.792 |
|
2009 |
Laroche C, Kerwin SM. Lithiation and functionalization of 1-alkynylimidazoles at the 2-position Tetrahedron Letters. 50: 5194-5197. DOI: 10.1016/J.Tetlet.2009.06.133 |
0.302 |
|
2009 |
Kerwin SM. DNA Damage Due to Diradical-Generating Cyclizations Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. 389-419. DOI: 10.1002/9780470526279.ch13 |
0.327 |
|
2009 |
Kerwin SM. DNA Damage Due to Diradical-Generating Cyclizations Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. 389-419. DOI: 10.1002/9780470526279.ch13 |
0.327 |
|
2008 |
Laroche C, Li J, Freyer MW, Kerwin SM. Coupling reactions of bromoalkynes with imidazoles mediated by copper salts: Synthesis of novel N-alkynylimidazoles Journal of Organic Chemistry. 73: 6462-6465. PMID 18646827 DOI: 10.1021/Jo801118Q |
0.322 |
|
2008 |
Tuesuwan B, Kern JT, Thomas PW, Rodriguez M, Li J, David WM, Kerwin SM. Simian virus 40 large T-antigen G-quadruplex DNA helicase inhibition by G-quadruplex DNA-interactive agents Biochemistry. 47: 1896-1909. PMID 18205402 DOI: 10.1021/Bi701747D |
0.789 |
|
2008 |
Tuesuwan B, Kern JT, Thomas PW, Rodriguez M, Li J, David WM, Kerwin SM. Simian virus 40 large T-antigen G-quadruplex DNA helicase inhibition by G-quadruplex DNA-interactive agents Biochemistry. 47: 1896-1909. PMID 18205402 DOI: 10.1021/bi701747d |
0.387 |
|
2008 |
McKee ML, Kerwin SM. Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2′-hydroxyphenyl)benzoxazole analogs of UK-1 Bioorganic and Medicinal Chemistry. 16: 1775-1783. PMID 18037301 DOI: 10.1016/J.Bmc.2007.11.019 |
0.558 |
|
2006 |
Sherman CL, Pierce SE, Brodbelt JS, Tuesuwan B, Kerwin SM. Identification of the Adduct Between a 4-Aza-3-ene-1,6-diyne and DNA Using Electrospray Ionization Mass Spectrometry Journal of the American Society For Mass Spectrometry. 17: 1342-1352. PMID 16872840 DOI: 10.1016/J.Jasms.2006.05.015 |
0.803 |
|
2006 |
Sherman CL, Pierce SE, Brodbelt JS, Tuesuwan B, Kerwin SM. Identification of the Adduct Between a 4-Aza-3-ene-1,6-diyne and DNA Using Electrospray Ionization Mass Spectrometry Journal of the American Society For Mass Spectrometry. 17: 1342-1352. PMID 16872840 DOI: 10.1016/j.jasms.2006.05.015 |
0.322 |
|
2006 |
Tuesuwan B, Kerwin SM. 2-Alkynyl-N-propargyl pyridinium salts: Pyridinium-based heterocyclic skipped aza-enediynes that cleave DNA by deoxyribosyl hydrogen-atom abstraction and guanine oxidation Biochemistry. 45: 7265-7276. PMID 16752915 DOI: 10.1021/Bi052519J |
0.824 |
|
2006 |
Feng L, Zhang A, Kerwin SM. Enediynes from aza-enediynes: C,N-dialkynyl imines undergo both aza-Bergman rearrangement and conversion to enediynes and fumaronitriles Organic Letters. 8: 1983-1986. PMID 16671762 DOI: 10.1021/Ol0600638 |
0.489 |
|
2006 |
Mazzitelli CL, Brodbelt JS, Kern JT, Rodriguez M, Kerwin SM. Evaluation of binding of perylene diimide and benzannulated perylene diimide ligands to DNA by electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 593-604. PMID 16503153 DOI: 10.1016/J.Jasms.2005.12.011 |
0.796 |
|
2006 |
Nadipuram AK, Kerwin SM. Intra- and intermolecular trapping of cyclopentapyrazine carbenes derived from 1,2-dialkynylimidazoles Tetrahedron Letters. 47: 353-356. DOI: 10.1016/J.Tetlet.2005.11.010 |
0.761 |
|
2006 |
Nadipuram AK, Kerwin SM. Thermal cyclization of 1,2-dialkynylimidazoles to imidazo[1,2-a]pyridines Tetrahedron. 62: 3798-3808. DOI: 10.1016/J.Tet.2005.11.084 |
0.767 |
|
2005 |
Pothukuchy A, Mazzitelli CL, Rodriguez ML, Tuesuwan B, Salazar M, Brodbelt JS, Kerwin SM. Duplex and quadruplex DNA binding and photocleavage by trioxatriangulenium ion. Biochemistry. 44: 2163-72. PMID 15697242 DOI: 10.1021/Bi0485981 |
0.821 |
|
2005 |
Pothukuchy A, Mazzitelli CL, Rodriguez ML, Tuesuwan B, Salazar M, Brodbelt JS, Kerwin SM. Duplex and quadruplex DNA binding and photocleavage by trioxatriangulenium ion. Biochemistry. 44: 2163-72. PMID 15697242 DOI: 10.1021/Bi0485981 |
0.821 |
|
2004 |
Oehlers L, Mazzitelli CL, Brodbelt JS, Rodriguez M, Kerwin S. Evaluation of complexes of DNA duplexes and novel benzoxazoles or benzimidazoles by electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 15: 1593-603. PMID 15519226 DOI: 10.1016/J.Jasms.2004.07.015 |
0.426 |
|
2004 |
Feng L, Kumar D, Birney DM, Kerwin SM. α,5-didehydro-3-picoline diradicals from skipped azaenediynes: Computational and trapping studies of an aza-Myers-Saito cyclization Organic Letters. 6: 2059-2062. PMID 15176818 DOI: 10.1021/Ol049266R |
0.48 |
|
2004 |
Kerwin SM, Nadipuram A. 5H-cyclopentapyrazines from 1,2-dialkynylimidazoles Synlett. 1404-1408. DOI: 10.1055/S-2004-825628 |
0.762 |
|
2003 |
Feng L, Kumar D, Kerwin SM. An extremely facile aza-Bergman rearrangement of sterically unencumbered acyclic 3-aza-3-ene-1,5-diynes. The Journal of Organic Chemistry. 68: 2234-42. PMID 12636386 DOI: 10.1021/Jo0267192 |
0.514 |
|
2003 |
Feng L, Kumar D, Kerwin SM. An extremely facile aza-Bergman rearrangement of sterically unencumbered acyclic 3-aza-3-ene-1,5-diynes Journal of Organic Chemistry. 68: 2234-2242. DOI: 10.1021/jo0267192 |
0.408 |
|
2003 |
Feng L, Kerwin SM. Isolation of a cyclopropane-containing product from the rearrangement of a 3-aza-3-ene-1,5-diyne under acid catalysis Tetrahedron Letters. 44: 3463-3466. DOI: 10.1016/S0040-4039(03)00675-0 |
0.471 |
|
2002 |
Nadipuram AK, David WM, Kumar D, Kerwin SM. Synthesis and Thermolysis of Heterocyclic 3-Aza-3-ene-1,5-diynes Organic Letters. 4: 4543-4546. PMID 12465933 DOI: 10.1021/Ol027100P |
0.745 |
|
2002 |
Kern JT, Kerwin SM. The aggregation and G-quadruplex DNA selectivity of charged 3,4,9,10-perylenetetracarboxylic acid diimides Bioorganic and Medicinal Chemistry Letters. 12: 3395-3398. PMID 12419369 DOI: 10.1016/S0960-894X(02)00763-1 |
0.8 |
|
2002 |
Kumar D, Jacob MR, Reynolds MB, Kerwin SM. Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1 Bioorganic and Medicinal Chemistry. 10: 3997-4004. PMID 12413851 DOI: 10.1016/S0968-0896(02)00327-9 |
0.34 |
|
2002 |
Kern JT, Thomas PW, Kerwin SM. The relationship between ligand aggregation and G-quadruplex DNA selectivity in a series of 3,4,9,10-perylenetetracarboxylic acid diimides Biochemistry. 41: 11379-11389. PMID 12234180 DOI: 10.1021/Bi0263107 |
0.802 |
|
2002 |
Kern JT, Thomas PW, Kerwin SM. The relationship between ligand aggregation and G-quadruplex DNA selectivity in a series of 3,4,9,10-perylenetetracarboxylic acid diimides Biochemistry. 41: 11379-11389. PMID 12234180 DOI: 10.1021/bi0263107 |
0.338 |
|
2002 |
David WM, Brodbelt J, Kerwin SM, Wang Thomas P. Investigation of quadruplex oligonucleotide - Drug interactions by electrospray ionization mass spectrometry Analytical Chemistry. 74: 2029-2033. PMID 12033303 DOI: 10.1021/Ac011283W |
0.77 |
|
2002 |
David WM, Brodbelt J, Kerwin SM, Wang Thomas P. Investigation of quadruplex oligonucleotide - Drug interactions by electrospray ionization mass spectrometry Analytical Chemistry. 74: 2029-2033. PMID 12033303 DOI: 10.1021/ac011283w |
0.314 |
|
2002 |
Tuntiwechapikul W, David WM, Kumar D, Salazar M, Kerwin SM. DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity Biochemistry. 41: 5283-5290. PMID 11955078 DOI: 10.1021/Bi025535E |
0.8 |
|
2002 |
Tuntiwechapikul W, David WM, Kumar D, Salazar M, Kerwin SM. DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity Biochemistry. 41: 5283-5290. PMID 11955078 DOI: 10.1021/bi025535e |
0.309 |
|
2002 |
Kerwin SM, Chen G, Kern JT, Thomas PW. Perylene diimide G-quadruplex DNA binding selectivity is mediated by ligand aggregation Bioorganic and Medicinal Chemistry Letters. 12: 447-450. PMID 11814817 DOI: 10.1016/S0960-894X(01)00775-2 |
0.777 |
|
2002 |
Kerwin SM, Chen G, Kern JT, Thomas PW. Perylene diimide G-quadruplex DNA binding selectivity is mediated by ligand aggregation Bioorganic and Medicinal Chemistry Letters. 12: 447-450. PMID 11814817 DOI: 10.1016/S0960-894X(01)00775-2 |
0.347 |
|
2001 |
Reyzer ML, Brodbelt JS, Kerwin SM, Kumar D. Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry. Nucleic Acids Research. 29: E103-103. PMID 11691940 DOI: 10.1093/Nar/29.21.E103 |
0.342 |
|
2001 |
Kumar D, David WM, Kerwin SM. N-propargyl-2-alkynylbenzothiazolium aza-enediynes: Role of the 2-alkynylbenzothiazolium functionality in DNA cleavage Bioorganic and Medicinal Chemistry Letters. 11: 2971-2974. PMID 11677138 DOI: 10.1016/S0960-894X(01)00606-0 |
0.801 |
|
2001 |
Kumar D, David WM, Kerwin SM. N-propargyl-2-alkynylbenzothiazolium aza-enediynes: Role of the 2-alkynylbenzothiazolium functionality in DNA cleavage Bioorganic and Medicinal Chemistry Letters. 11: 2971-2974. PMID 11677138 DOI: 10.1016/S0960-894X(01)00606-0 |
0.326 |
|
2001 |
McPhee MM, Kerwin SM. Synthesis, DNA cleavage, and cytotoxicity of a series of bis(propargylic) sulfone crown ethers Bioorganic and Medicinal Chemistry. 9: 2809-2818. PMID 11597461 DOI: 10.1016/S0968-0896(01)00150-X |
0.352 |
|
2001 |
McPhee MM, Kerwin SM. Synthesis, DNA cleavage, and cytotoxicity of a series of bis(propargylic) sulfone crown ethers Bioorganic and Medicinal Chemistry. 9: 2809-2818. PMID 11597461 DOI: 10.1016/S0968-0896(01)00150-X |
0.392 |
|
2001 |
Kerwin SM, Sun D, Kern JT, Rangan A, Thomas PW. G-quadruplex DNA binding by a series of carbocyanine dyes Bioorganic and Medicinal Chemistry Letters. 11: 2411-2414. PMID 11549435 DOI: 10.1016/S0960-894X(01)00490-5 |
0.802 |
|
2001 |
Kerwin SM, Sun D, Kern JT, Rangan A, Thomas PW. G-quadruplex DNA binding by a series of carbocyanine dyes Bioorganic and Medicinal Chemistry Letters. 11: 2411-2414. PMID 11549435 DOI: 10.1016/S0960-894X(01)00490-5 |
0.416 |
|
2001 |
Fletcher TM, Cathers BE, Ravikumar KS, Mamiya BM, Kerwin SM. Inhibition of human telomerase by 7-deaza-2′-deoxyguanosine nucleoside triphosphate analogs: Potent inhibition by 6-thio-7-deaza-2′-deoxyguanosine 5′-triphosphate Bioorganic Chemistry. 29: 36-55. PMID 11300694 DOI: 10.1006/Bioo.2000.1194 |
0.358 |
|
2001 |
Kumar D, Kanz B, Mamiya BM, Kern JT, Kerwin SM. Synthesis of a phosphoramidate pro-drug of 6-thio-7-deaza-2′-deoxyguanosine (TDG): A regioselective phosphorylation Tetrahedron Letters. 42: 565-567. DOI: 10.1016/S0040-4039(00)02045-1 |
0.731 |
|
2000 |
David WM, Kumar D, Kerwin SM. Synthesis of a heterocyclic aza-enediyne and its DNA-cleavage properties Bioorganic and Medicinal Chemistry Letters. 10: 2509-2512. PMID 11086717 DOI: 10.1016/S0960-894X(00)00516-3 |
0.793 |
|
2000 |
David WM, Kumar D, Kerwin SM. Synthesis of a heterocyclic aza-enediyne and its DNA-cleavage properties Bioorganic and Medicinal Chemistry Letters. 10: 2509-2512. PMID 11086717 |
0.363 |
|
2000 |
Yu H, Kwok Y, Hurley LH, Kerwin SM. Efficient, Mg(2+)-dependent photochemical DNA cleavage by the antitumor quinobenzoxazine (S)-A-62176. Biochemistry. 39: 10236-46. PMID 10956013 DOI: 10.1021/Bi001103X |
0.395 |
|
2000 |
Yu H, Kwok Y, Hurley LH, Kerwin SM. Efficient, Mg(2+)-dependent photochemical DNA cleavage by the antitumor quinobenzoxazine (S)-A-62176. Biochemistry. 39: 10236-46. PMID 10956013 DOI: 10.1021/Bi001103X |
0.395 |
|
2000 |
Kerwin SM. G-quadruplex DNA as a target for drug design Current Pharmaceutical Design. 6: 441-471. PMID 10788591 DOI: 10.2174/1381612003400849 |
0.494 |
|
2000 |
Hurley LH, Wheelhouse RT, Sun D, Kerwin SM, Salazar M, Fedoroff OY, Han FX, Han H, Izbicka E, Von Hoff DD. G-quadruplexes as targets for drug design. Pharmacology & Therapeutics. 85: 141-58. PMID 10739869 DOI: 10.1016/S0163-7258(99)00068-6 |
0.356 |
|
2000 |
Hurley LH, Wheelhouse RT, Sun D, Kerwin SM, Salazar M, Fedoroff OY, Han FX, Han H, Izbicka E, Von Hoff DD. G-quadruplexes as targets for drug design. Pharmacology & Therapeutics. 85: 141-58. PMID 10739869 DOI: 10.1016/S0163-7258(99)00068-6 |
0.356 |
|
2000 |
McPhee MM, Kern JT, Hoster BC, Kerwin SM. Propargylic sulfone-armed lariat crown ethers: Alkali metal ion- regulated DNA cleavage agents Bioorganic Chemistry. 28: 98-118. DOI: 10.1006/Bioo.1999.1167 |
0.763 |
|
1999 |
Reynolds MB, Deluca MR, Kerwin SM. The novel bis(Benzoxazole) cytotoxic natural product UK-1 is a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II Bioorganic Chemistry. 27: 326-337. DOI: 10.1006/Bioo.1999.1138 |
0.412 |
|
1998 |
Zeng Q, Kwok Y, Kerwin SM, Mangold G, Hurley LH. Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model. Journal of Medicinal Chemistry. 41: 4273-8. PMID 9784102 DOI: 10.1021/Jm980265C |
0.32 |
|
1998 |
Fedoroff OY, Salazar M, Han H, Chemeris VV, Kerwin SM, Hurley LH. NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA. Biochemistry. 37: 12367-74. PMID 9730808 DOI: 10.1021/Bi981330N |
0.404 |
|
1998 |
Fedoroff OY, Salazar M, Han H, Chemeris VV, Kerwin SM, Hurley LH. NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA. Biochemistry. 37: 12367-74. PMID 9730808 DOI: 10.1021/Bi981330N |
0.404 |
|
1997 |
David WM, Kerwin SM. Synthesis and thermal rearrangement of C,N-dialkynyl imines: A potential aza-Bergman route to 2,5-didehydropyridine Journal of the American Chemical Society. 119: 1464-1465. DOI: 10.1021/Ja962328R |
0.727 |
|
1997 |
DeLuca MR, Kerwin SM. The total synthesis of UK-1 Tetrahedron Letters. 38: 199-202. DOI: 10.1016/S0040-4039(96)02288-5 |
0.324 |
|
1997 |
DeLuca MR, Kerwin SM. The para-toluenesulfonic acid-promoted synthesis of 2-substituted benzoxazoles and benzimidazoles from diacylated precursors Tetrahedron. 53: 457-464. DOI: 10.1016/S0040-4020(96)01009-5 |
0.316 |
|
1996 |
Salazar M, Thompson BD, Kerwin SM, Hurley LH. Thermally induced DNA.RNA hybrid to G-quadruplex transitions: possible implications for telomere synthesis by telomerase. Biochemistry. 35: 16110-5. PMID 8973182 DOI: 10.1021/Bi961442J |
0.315 |
|
1996 |
Salazar M, Thompson BD, Kerwin SM, Hurley LH. Thermally induced DNA.RNA hybrid to G-quadruplex transitions: possible implications for telomere synthesis by telomerase. Biochemistry. 35: 16110-5. PMID 8973182 DOI: 10.1021/Bi961442J |
0.315 |
|
1996 |
McPhee MM, Kerwin SM. Synthesis and metal ion binding studies of enediyne-containing crown ethers Journal of Organic Chemistry. 61: 9385-9393. DOI: 10.1021/Jo961583R |
0.345 |
|
1996 |
Yu H, Hurley LH, Kerwin SM. Evidence for the formation of 2:2 drug-Mg2+ dimers in solution and for the formation of dimeric drug complexes on DNA from the DNA-accelerated photochemical reaction of antineoplastic quinobenzoxazines Journal of the American Chemical Society. 118: 7040-7048. DOI: 10.1021/Ja9602859 |
0.446 |
|
1995 |
Fan JY, Sun D, Yu H, Kerwin SM, Hurley LH. Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. Journal of Medicinal Chemistry. 38: 408-24. PMID 7853333 DOI: 10.1021/Jm00003A003 |
0.319 |
|
1995 |
Fan JY, Sun D, Yu H, Kerwin SM, Hurley LH. Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. Journal of Medicinal Chemistry. 38: 408-24. PMID 7853333 DOI: 10.1021/Jm00003A003 |
0.319 |
|
1995 |
Watts CR, Kerwin SM, Kenyon GL, Kuntz ID, Kallick DA. Rationally designed N,N′-bis[(N-p-guanidinobenzyl-N-methyl)aminocarbonyl]-1,3-diaminobenzene, "BIGBEN", binds to the minor groove of d(CGCGAATTCGCG)2 as determined by two-dimensional nuclear magnetic resonance spectroscopy Journal of the American Chemical Society. 117: 9941-9950. DOI: 10.1021/Ja00145A002 |
0.475 |
|
1995 |
Watts CR, Kerwin SM, Kenyon GL, Kuntz ID, Kallick DA. Rationally designed N,N′-bis[(N-p-guanidinobenzyl-N-methyl)aminocarbonyl]-1,3-diaminobenzene, "BIGBEN", binds to the minor groove of d(CGCGAATTCGCG)2 as determined by two-dimensional nuclear magnetic resonance spectroscopy Journal of the American Chemical Society. 117: 9941-9950. DOI: 10.1021/Ja00145A002 |
0.475 |
|
1994 |
Kerwin SM. Synthesis of a DNA-cleaving bis(propargylic) sulfone crown ether Tetrahedron Letters. 35: 1023-1026. DOI: 10.1016/S0040-4039(00)79955-2 |
0.384 |
|
1994 |
Kerwin SM. Synthesis of a DNA-cleaving bis(propargylic) sulfone crown ether Tetrahedron Letters. 35: 1023-1026. DOI: 10.1016/S0040-4039(00)79955-2 |
0.475 |
|
1993 |
Mujeeb A, Kerwin SM, Kenyon GL, James TL. Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra. Biochemistry. 32: 13419-31. PMID 8257678 DOI: 10.1021/Bi00212A007 |
0.588 |
|
1992 |
Mujeeb A, Kerwin SM, Egan W, Kenyon GL, James TL. A potential gene target in HIV-1: rationale, selection of a conserved sequence, and determination of NMR distance and torsion angle constraints. Biochemistry. 31: 9325-38. PMID 1327112 DOI: 10.1021/Bi00154A002 |
0.542 |
|
1992 |
Kerwin SM, Heathcock CH. Remote oxidation of perhydrophenanthrenes by template-directed hydrogen atom abstraction Journal of Organic Chemistry. 57: 4005-4013. DOI: 10.1021/Jo00040A050 |
0.41 |
|
1992 |
Kerwin SM, Heathcock CH. Remote oxidation of perhydrophenanthrenes by template-directed hydrogen atom abstraction Journal of Organic Chemistry. 57: 4005-4013. DOI: 10.1021/Jo00040A050 |
0.41 |
|
1987 |
Kerwin SM, Paul AG, Heathcock CH. Quassinoid synthesis. 2. Preparation of a tetracyclic intermediate having the bruceantin tetrahydrofuran ring Journal of Organic Chemistry. 52: 1686-1695. DOI: 10.1021/Jo00385A008 |
0.504 |
|
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