| Year |
Citation |
Score |
| 2023 |
Fiorin G, Forrest LR, Faraldo-Gómez JD. Membrane free-energy landscapes derived from atomistic dynamics explain nonuniversal cholesterol-induced stiffening. Pnas Nexus. 2: pgad269. PMID 37637198 DOI: 10.1093/pnasnexus/pgad269 |
0.312 |
|
| 2023 |
Fiorin G, Forrest LR, Faraldo-Gómez JD. Membrane free-energy landscapes derived from atomistic dynamics explain nonuniversal cholesterol-induced stiffening. Biorxiv : the Preprint Server For Biology. PMID 36778237 DOI: 10.1101/2023.02.02.525347 |
0.311 |
|
| 2022 |
Leone V, Bradshaw RT, Koshy C, Lee PS, Fenollar-Ferrer C, Heinz V, Ziegler C, Forrest LR. Insights into autoregulation of a membrane protein complex by its cytoplasmic domains. Biophysical Journal. PMID 36528790 DOI: 10.1016/j.bpj.2022.12.021 |
0.452 |
|
| 2022 |
Staritzbichler R, Yaklich E, Sarti E, Ristic N, Hildebrand PW, Forrest LR. AlignMe: an update of the web server for alignment of membrane protein sequences. Nucleic Acids Research. PMID 35609986 DOI: 10.1093/nar/gkac391 |
0.308 |
|
| 2021 |
Zhang YW, Uchendu S, Leone V, Bradshaw RT, Sangwa N, Forrest LR, Rudnick G. Chloride-dependent conformational changes in the GlyT1 glycine transporter. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33658361 DOI: 10.1073/pnas.2017431118 |
0.358 |
|
| 2020 |
Huffer KE, Aleksandrova AA, Jara-Oseguera A, Forrest LR, Swartz KJ. Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms. Elife. 9. PMID 32804077 DOI: 10.7554/Elife.58660 |
0.397 |
|
| 2020 |
Bradshaw RT, Marinelli F, Faraldo-Gómez JD, Forrest LR. Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles. Biophysical Journal. PMID 32105651 DOI: 10.1016/J.Bpj.2020.02.005 |
0.425 |
|
| 2020 |
Huffer KE, Aleksandrova AA, Jara-Oseguera A, Forrest LR, Swartz KJ. Author response: Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms Elife. DOI: 10.7554/Elife.58660.Sa2 |
0.324 |
|
| 2020 |
Marinelli F, Bradshaw R, Faraldo-Gómez JD, Forrest LR. Structural Interpretation of Hydrogen-deuterium Exchange with Maximum-entropy Simulation Reweighting Biophysical Journal. 118: 301a-302a. DOI: 10.1016/J.Bpj.2019.11.1707 |
0.329 |
|
| 2019 |
Zhou W, Fiorin G, Anselmi C, Karimi-Varzaneh HA, Poblete H, Forrest LR, Faraldo-Gómez JD. Large-scale state-dependent membrane remodeling by a transporter protein. Elife. 8. PMID 31855177 DOI: 10.7554/Elife.50576 |
0.519 |
|
| 2019 |
Aleksandrova AA, Sarti E, Forrest LR. MemSTATS: A Benchmark Set of Membrane Protein Symmetries and Pseudo-Symmetries. Journal of Molecular Biology. PMID 31628944 DOI: 10.1016/J.Jmb.2019.09.020 |
0.425 |
|
| 2019 |
Hellsberg E, Ecker GF, Stary-Weinzinger A, Forrest LR. A structural model of the human serotonin transporter in an outward-occluded state. Plos One. 14: e0217377. PMID 31251747 DOI: 10.1371/Journal.Pone.0217377 |
0.492 |
|
| 2019 |
Leone V, Waclawska I, Kossmann K, Koshy C, Sharma M, Prisner TF, Ziegler C, Endeward B, Forrest LR. Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP. The Journal of General Physiology. PMID 30728216 DOI: 10.1085/jgp.201812111 |
0.497 |
|
| 2019 |
Zhou W, Fiorin G, Anselmi C, Karimi-Varzaneh HA, Poblete H, Forrest LR, Faraldo-Gómez JD. Author response: Large-scale state-dependent membrane remodeling by a transporter protein Elife. DOI: 10.7554/Elife.50576.Sa2 |
0.438 |
|
| 2018 |
Sarti E, Aleksandrova AA, Ganta SK, Yavatkar AS, Forrest LR. EncoMPASS: an online database for analyzing structure and symmetry in membrane proteins. Nucleic Acids Research. PMID 30357403 DOI: 10.1093/Nar/Gky952 |
0.483 |
|
| 2018 |
Zhang YW, Tavoulari S, Sinning S, Aleksandrova AA, Forrest LR, Rudnick G. Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181291 DOI: 10.1073/Pnas.1716870115 |
0.472 |
|
| 2018 |
Fenollar-Ferrer C, Forrest LR. Structural models of the NaPi-II sodium-phosphate cotransporters. Pflugers Archiv : European Journal of Physiology. PMID 30175376 DOI: 10.1007/S00424-018-2197-X |
0.471 |
|
| 2018 |
Yaffe D, Forrest LR, Schuldiner S. The ins and outs of vesicular monoamine transporters. The Journal of General Physiology. PMID 29666153 DOI: 10.1085/Jgp.201711980 |
0.474 |
|
| 2018 |
Giovanola M, Vollero A, Cinquetti R, Bossi E, Forrest LR, Di Cairano ES, Castagna M. Threonine 67 is a key component in the coupling of the NSS amino acid transporter KAAT1. Biochimica Et Biophysica Acta. Biomembranes. 1860: 1179-1186. PMID 29409909 DOI: 10.1016/J.Bbamem.2018.01.020 |
0.404 |
|
| 2018 |
Leone V, Waclawska I, Endeward B, Prisner T, Ziegler C, Forrest LR. Coupling Spectroscopic Data for a Secondary Transporter with Simulations to Assess the Role of a Key Acidic Residue Biophysical Journal. 114: 332a-333a. DOI: 10.1016/J.Bpj.2017.11.1863 |
0.364 |
|
| 2018 |
Hellsberg E, Forrest LR, Stary-Weinzinger A, Ecker GF. Selectivity Profiling of the Human Monoamine Transporters: Investigation of the Serotonin Transporter Mechanism Biophysical Journal. 114: 332a. DOI: 10.1016/J.Bpj.2017.11.1860 |
0.332 |
|
| 2018 |
Bradshaw RT, Nagarajan A, Adhikary S, Deredge DJ, Wintrode PL, Singh SK, Forrest LR. Neurotransmitter Transporter Conformational Dynamics using HDX-MS and Molecular Dynamics Simulation Biophysical Journal. 114: 207a. DOI: 10.1016/J.Bpj.2017.11.1161 |
0.616 |
|
| 2018 |
Sarti E, Aleksandrova A, Forrest LR. Analyzing the Structure and Symmetry of Membrane Proteins through the Systematic Online Database EncoMPASS Biophysical Journal. 114: 190a. DOI: 10.1016/J.Bpj.2017.11.1061 |
0.465 |
|
| 2017 |
Ficici E, Faraldo-Gómez JD, Jennings ML, Forrest LR. Asymmetry of inverted-topology repeats in the AE1 anion exchanger suggests an elevator-like mechanism. The Journal of General Physiology. 149: 1149-1164. PMID 29167180 DOI: 10.1085/Jgp.201711836 |
0.48 |
|
| 2017 |
Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK. Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223522 DOI: 10.1073/Pnas.1613293114 |
0.721 |
|
| 2017 |
Dayan O, Nagarajan A, Shah R, Ben-Yona A, Forrest LR, Kanner BI. An extra amino acid residue in transmembrane domain 10 of the GABA transporter GAT-1 is required for efficient ion-coupled transport. The Journal of Biological Chemistry. PMID 28213519 DOI: 10.1074/Jbc.M117.775189 |
0.63 |
|
| 2017 |
Becerril AJ, Fenollar-Ferrer C, Forrest LR, Mindell JA. It Runs in the Family: Determining the Transport Mechanism of Sodium/Dicarboxylate Symporter hNaDC3 Biophysical Journal. 112: 129a-130a. DOI: 10.1016/J.Bpj.2016.11.720 |
0.487 |
|
| 2017 |
Zhou W, Anselmi C, Poblete H, Karimi A, Forrest L, Faraldo-Gomez J. Membrane Remodeling by Glt Ph in the Inward- and Outward-Facing Conformations Explains Lack of Protomer Cooperativity Biophysical Journal. 112: 129a. DOI: 10.1016/J.Bpj.2016.11.718 |
0.518 |
|
| 2017 |
Zhang Y, Forrest LR, Rudnick G. Substrate-Induced Conformational Change in LeuT Biophysical Journal. 112: 129a. DOI: 10.1016/J.Bpj.2016.11.717 |
0.456 |
|
| 2017 |
Leone V, Waclawska I, Endeward B, Prisner T, Ziegler C, Forrest LR. Describing the Thermodynamics of the Secondary Transporter BetP by Coupling Spectroscopic Measurements to Molecular Dynamics Simulations Biophysical Journal. 112: 335a. DOI: 10.1016/J.Bpj.2016.11.1816 |
0.442 |
|
| 2017 |
Ficici E, Faraldo-Gomez JD, Forrest LR, Jennings ML. Repeat-Swap Homology Modeling of the Anion Exchanger AE1 Reveals an Elevator-Like Antiport Mechanism Biophysical Journal. 112: 275a. DOI: 10.1016/J.Bpj.2016.11.1490 |
0.457 |
|
| 2016 |
Yaffe D, Vergara-Jaque A, Forrest LR, Schuldiner S. Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821772 DOI: 10.1073/Pnas.1605162113 |
0.451 |
|
| 2016 |
Patti M, Fenollar-Ferrer C, Werner A, Forrest LR, Forster IC. Cation Interactions and Membrane Potential Induce Conformational Changes in NaPi-IIb. Biophysical Journal. 111: 973-988. PMID 27602725 DOI: 10.1016/J.Bpj.2016.07.025 |
0.496 |
|
| 2016 |
Stamm M, Forrest LR. Structure alignment of membrane proteins: Accuracy of available tools and a consensus strategy. Proteins. 84: 1333. PMID 27516158 DOI: 10.1002/Prot.25098 |
0.453 |
|
| 2016 |
Davis BA, Nagarajan A, Forrest LR, Singh SK. Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. Scientific Reports. 6: 23789. PMID 27032980 DOI: 10.1038/Srep23789 |
0.645 |
|
| 2016 |
Mulligan C, Fenollar-Ferrer C, Fitzgerald GA, Vergara-Jaque A, Kaufmann D, Li Y, Forrest LR, Mindell JA. The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism. Nature Structural & Molecular Biology. 23: 256-63. PMID 26828963 DOI: 10.1038/Nsmb.3166 |
0.441 |
|
| 2016 |
Abraham SJ, Chavan T, Cheng RC, Fenollar-Ferrer C, Han W, Islam SM, Jiang T, Khantwal CM, Mathews II, Stein RA, Roux B, Forrest LR, Mchaourab HS, Tajkhorshid E, Maduke M. An Outward-Facing Open Conformational State in a CLC Transporter Biophysical Journal. 110: 178a. DOI: 10.1016/J.Bpj.2015.11.994 |
0.579 |
|
| 2016 |
Fenollar-Ferrer C, Anselmi C, Vergara Jaque A, Ali Karimi-Verzaneh H, Poblete-Vilches H, Mulligan C, Forster IC, Mindell JA, Faraldo-Gómez JD, Forrest LR. Computational Studies of Elevator-Like Movements in Secondary Transport Biophysical Journal. 110: 626a-627a. DOI: 10.1016/J.Bpj.2015.11.3359 |
0.56 |
|
| 2016 |
Zhao J, Krystofiak E, Fenollar Ferrer C, Ballesteros Morcillo A, van Itallie C, Cui R, Anderson J, Forrest L, Kachar B. Probing the Intermolecular Interfaces between Claudin Protomers Biophysical Journal. 110: 216a. DOI: 10.1016/J.Bpj.2015.11.1200 |
0.413 |
|
| 2015 |
Tavoulari S, Margheritis E, Nagarajan A, DeWitt DC, Zhang YW, Rosado E, Ravera S, Rhoades E, Forrest LR, Rudnick G. Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog. The Journal of Biological Chemistry. PMID 26582198 DOI: 10.1074/Jbc.M115.692012 |
0.644 |
|
| 2015 |
Vergara-Jaque A, Fenollar-Ferrer C, Mulligan C, Mindell JA, Forrest LR. Family resemblances: A common fold for some dimeric ion-coupled secondary transporters. The Journal of General Physiology. 146: 423-34. PMID 26503722 DOI: 10.1085/Jgp.201511481 |
0.513 |
|
| 2015 |
Silverstein N, Ewers D, Forrest LR, Fahlke C, Kanner BI. Molecular Determinants of Substrate Specificity in Sodium-Coupled Glutamate Transporters. The Journal of Biological Chemistry. PMID 26475859 DOI: 10.1074/Jbc.M115.682666 |
0.366 |
|
| 2015 |
Vergara-Jaque A, Fenollar-Ferrer C, Kaufmann D, Forrest LR. Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms. Frontiers in Pharmacology. 6: 183. PMID 26388773 DOI: 10.3389/Fphar.2015.00183 |
0.541 |
|
| 2015 |
Schweikhard ES, Burckhardt BC, Joos F, Fenollar-Ferrer C, Forrest LR, Kempson SA, Ziegler C. Role of N-glycosylation in renal betaine transport. The Biochemical Journal. 470: 169-79. PMID 26348906 DOI: 10.1042/Bj20131031 |
0.387 |
|
| 2015 |
Stamm M, Forrest LR. Structure alignment of membrane proteins: Accuracy of available tools and a consensus strategy. Proteins. 83: 1720-32. PMID 26178143 DOI: 10.1002/Prot.24857 |
0.45 |
|
| 2015 |
Forrest LR. Structural Symmetry in Membrane Proteins∗ Annual Review of Biophysics. 44: 311-337. PMID 26098517 DOI: 10.1146/Annurev-Biophys-051013-023008 |
0.487 |
|
| 2015 |
Fenollar-Ferrer C, Forster IC, Patti M, Knoepfel T, Werner A, Forrest LR. Identification of the first sodium binding site of the phosphate cotransporter NaPi-IIa (SLC34A1). Biophysical Journal. 108: 2465-80. PMID 25992725 DOI: 10.1016/J.Bpj.2015.03.054 |
0.398 |
|
| 2015 |
Fowler PW, Orwick-Rydmark M, Radestock S, Solcan N, Dijkman PM, Lyons JA, Kwok J, Caffrey M, Watts A, Forrest LR, Newstead S. Gating topology of the proton-coupled oligopeptide symporters. Structure (London, England : 1993). 23: 290-301. PMID 25651061 DOI: 10.1016/J.Str.2014.12.012 |
0.494 |
|
| 2015 |
Vergara-Jaque A, Yaffe D, Shuster Y, Listov D, Meena S, Singh SK, Schuldiner S, Forrest LR. Carboxyl Residues Required for Transport by a Vesicular Monoamine Transporter Homolog from Brevibacillus Brevis (BbMAT) Biophysical Journal. 108: 462a. DOI: 10.1016/J.Bpj.2014.11.2522 |
0.458 |
|
| 2015 |
Patti M, Fenollar-Ferrer C, Werner A, Knöpfel T, Forrest L, Forster I. Functional Identification of the Na1 Site of the Phosphate Cotransporter NaPi-IIa Biophysical Journal. 108: 29a. DOI: 10.1016/J.Bpj.2014.11.184 |
0.418 |
|
| 2015 |
Fenollar-Ferrer C, Patti M, Werner A, Knoepfel T, Forster IC, Forrest LR. The Na1 Binding Site in the Human Sodium-Phosphate Cotransporter NaPi-IIa Biophysical Journal. 108: 29a. DOI: 10.1016/J.Bpj.2014.11.183 |
0.449 |
|
| 2014 |
Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S. Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). The Journal of Biological Chemistry. 289: 34229-40. PMID 25336661 DOI: 10.1074/Jbc.M114.607366 |
0.427 |
|
| 2014 |
Fenollar-Ferrer C, Stockner T, Schwarz TC, Pal A, Gotovina J, Hofmaier T, Jayaraman K, Adhikary S, Kudlacek O, Mehdipour AR, Tavoulari S, Rudnick G, Singh SK, Konrat R, Sitte HH, ... Forrest LR, et al. Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter. Biochemistry. 53: 5444-60. PMID 25093911 DOI: 10.1021/Bi500637F |
0.455 |
|
| 2014 |
Perez C, Faust B, Mehdipour AR, Francesconi KA, Forrest LR, Ziegler C. Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling. Nature Communications. 5: 4231. PMID 25023443 DOI: 10.1038/Ncomms5231 |
0.458 |
|
| 2014 |
Stamm M, Staritzbichler R, Khafizov K, Forrest LR. AlignMe--a membrane protein sequence alignment web server. Nucleic Acids Research. 42: W246-51. PMID 24753425 DOI: 10.1093/Nar/Gku291 |
0.354 |
|
| 2014 |
Fenollar-Ferrer C, Patti M, Knöpfel T, Werner A, Forster IC, Forrest LR. Structural fold and binding sites of the human Naâº-phosphate cotransporter NaPi-II. Biophysical Journal. 106: 1268-79. PMID 24655502 DOI: 10.1016/J.Bpj.2014.01.043 |
0.488 |
|
| 2014 |
Cheng RC, Chang P, Fenollar-Ferrer C, Stein RA, Trone K, Forrest LR, Mchaourab HS, Maduke MC. Monitoring Substrate-Driven Structural Changes in a CLC Chloride-Proton Antiporter with Double Electron-Electron Resonance Spectroscopy Biophysical Journal. 106: 145a. DOI: 10.1016/J.Bpj.2013.11.839 |
0.397 |
|
| 2014 |
Perez C, Faust B, Mehdipour AR, Francesconi KA, Forrest LR, Ziegler C. Substrate Bound Outward-Open State of the Symporter BetP: Insights Into Sodium and Substrate Binding and Coupling Biophysical Journal. 106: 363a-364a. DOI: 10.1016/J.Bpj.2013.11.2063 |
0.446 |
|
| 2014 |
Rudnick G, Tavoulari S, Zhang Y, DeWitt D, Nagarajan A, Rosado E, Ravera S, Kreuder A, Forrest LR, Rhoades E. The Role of Sodium Sites in LeuT Conformational Changes Biophysical Journal. 106: 228a-229a. DOI: 10.1016/J.Bpj.2013.11.1337 |
0.654 |
|
| 2014 |
Fenollar-Ferrer MC, Patti M, Knoepfel T, Werner A, Forster IC, Forrest LR. Structural Model of the Human Sodium-Phosphate Cotransporter NaPi-II Biophysical Journal. 106: 228a. DOI: 10.1016/J.Bpj.2013.11.1335 |
0.451 |
|
| 2013 |
Yaffe D, Radestock S, Shuster Y, Forrest LR, Schuldiner S. Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the United States of America. 110: E1332-41. PMID 23530208 DOI: 10.1073/Pnas.1220497110 |
0.478 |
|
| 2013 |
Stamm M, Staritzbichler R, Khafizov K, Forrest LR. Alignment of helical membrane protein sequences using AlignMe. Plos One. 8: e57731. PMID 23469223 DOI: 10.1371/Journal.Pone.0057731 |
0.459 |
|
| 2013 |
Forrest LR. (Pseudo-)symmetrical transport Science. 339: 399-401. PMID 23349276 DOI: 10.1126/Science.1228465 |
0.493 |
|
| 2013 |
Silverstein N, Crisman TJ, Forrest LR, Kanner BI. Cysteine scanning mutagenesis of transmembrane helix 3 of a brain glutamate transporter reveals two conformationally sensitive positions. The Journal of Biological Chemistry. 288: 964-73. PMID 23188832 DOI: 10.1074/Jbc.M112.403576 |
0.473 |
|
| 2013 |
Fowler PW, Orwick-Rydmark M, Solcan N, Radestock S, Dijkman P, Kwok J, Samsudin F, Watts A, Forrest L, Newstead S. Using DEER, Modelling and Simulations to Investigate the Dynamics of PepTSo, a Major Facilitator Superfamily Transporter of Biomedical Importance Biophysical Journal. 104: 199a. DOI: 10.1016/J.Bpj.2012.11.1124 |
0.472 |
|
| 2012 |
Gradogna A, Fenollar-Ferrer C, Forrest LR, Pusch M. Dissecting a regulatory calcium-binding site of CLC-K kidney chloride channels. The Journal of General Physiology. 140: 681-96. PMID 23148261 DOI: 10.1085/Jgp.201210878 |
0.309 |
|
| 2012 |
Khafizov K, Perez C, Koshy C, Quick M, Fendler K, Ziegler C, Forrest LR. Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP. Proceedings of the National Academy of Sciences of the United States of America. 109: E3035-44. PMID 23047697 DOI: 10.1073/Pnas.1209039109 |
0.455 |
|
| 2012 |
Schushan M, Rimon A, Haliloglu T, Forrest LR, Padan E, Ben-Tal N. A model-structure of a periplasm-facing state of the NhaA antiporter suggests the molecular underpinnings of pH-induced conformational changes. The Journal of Biological Chemistry. 287: 18249-61. PMID 22431724 DOI: 10.1074/Jbc.M111.336446 |
0.416 |
|
| 2011 |
Staritzbichler R, Anselmi C, Forrest LR, Faraldo-Gómez JD. GRIFFIN: A versatile methodology for optimization of protein-lipid interfaces for membrane protein simulations. Journal of Chemical Theory and Computation. 7: 1167-1176. PMID 24707227 DOI: 10.1021/Ct100576M |
0.475 |
|
| 2011 |
Perez C, Khafizov K, Forrest LR, Krämer R, Ziegler C. The role of trimerization in the osmoregulated betaine transporter BetP. Embo Reports. 12: 804-10. PMID 21681199 DOI: 10.1038/Embor.2011.102 |
0.468 |
|
| 2011 |
Faraldo-Gómez JD, Forrest LR. Modeling and simulation of ion-coupled and ATP-driven membrane proteins. Current Opinion in Structural Biology. 21: 173-9. PMID 21333528 DOI: 10.1016/J.Sbi.2011.01.013 |
0.489 |
|
| 2011 |
Radestock S, Forrest LR. The alternating-access mechanism of MFS transporters arises from inverted-topology repeats Journal of Molecular Biology. 407: 698-715. PMID 21315728 DOI: 10.1016/J.Jmb.2011.02.008 |
0.477 |
|
| 2011 |
Tsai CJ, Khafizov K, Hakulinen J, Forrest LR, Forrest LR, Krämer R, Kühlbrandt W, Ziegler C. Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum. Journal of Molecular Biology. 407: 368-81. PMID 21281647 DOI: 10.1016/J.Jmb.2011.01.028 |
0.409 |
|
| 2011 |
Tavoulari S, Rizwan AN, Forrest LR, Rudnick G. Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue. The Journal of Biological Chemistry. 286: 2834-42. PMID 21115480 DOI: 10.1074/Jbc.M110.186064 |
0.431 |
|
| 2011 |
Forrest LR, Krämer R, Ziegler C. The structural basis of secondary active transport mechanisms. Biochimica Et Biophysica Acta. 1807: 167-88. PMID 21029721 DOI: 10.1016/J.Bbabio.2010.10.014 |
0.496 |
|
| 2011 |
Tsai C, Khafizov K, Hakulinen J, Forrest LR, Krämer R, Kühlbrandt W, Ziegler C. Corrigendum to “Structural Asymmetry in a Trimeric Na+/Betaine Symporter, BetP, from Corynebacterium glutamicum” [J. Mol. Biol. 407/3 (2011) 368–381] Journal of Molecular Biology. 409: 879. DOI: 10.1016/J.Jmb.2011.04.054 |
0.316 |
|
| 2011 |
Khafizov K, Perez C, Tsai C, Ziegler C, Forrest LR. Computational and Experimental Studies of Substrate Binding, Conformational Change and Importance of the Trimeric State in the Glycine Betaine Transporter BetP Biophysical Journal. 100: 132a. DOI: 10.1016/J.Bpj.2010.12.927 |
0.475 |
|
| 2011 |
Radestock S, Forrest LR. Alternating Access Mechanism in the Lactose Permease Derived from its Internal Symmetry Biophysical Journal. 100: 247a. DOI: 10.1016/J.Bpj.2010.12.1568 |
0.514 |
|
| 2011 |
Fenollar-Ferrer C, Forrest LR. A structural Role for Serotonin Transporter Terminal Domains in Uptake Regulation Biophysical Journal. 100: 205a. DOI: 10.1016/J.Bpj.2010.12.1330 |
0.434 |
|
| 2010 |
Khafizov K, Staritzbichler R, Stamm M, Forrest LR. A study of the evolution of inverted-topology repeats from LeuT-fold transporters using AlignMe. Biochemistry. 49: 10702-13. PMID 21073167 DOI: 10.1021/Bi101256X |
0.497 |
|
| 2010 |
Randa HS, Forrest LR, Voth GA, Sansom MS. Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane. Biophysical Journal. 77: 2400-10. PMID 10545343 DOI: 10.1016/S0006-3495(99)77077-3 |
0.564 |
|
| 2010 |
Crisman TJ, Qu S, Kanner B, Forrest L. Symmetry in the Structure of the Glutamate Transporter GltPh Suggests Conformation of an Alternate State Biophysical Journal. 98: 628a. DOI: 10.1016/J.Bpj.2009.12.3440 |
0.46 |
|
| 2010 |
Staritzbichler R, Forrest LR, Faraldo-Gómez JD. Automated and Optimized Embedding of Proteins into Membranes for Molecular Dynamics Simulations using Griffin Biophysical Journal. 98: 566a. DOI: 10.1016/J.Bpj.2009.12.3070 |
0.473 |
|
| 2010 |
Staritzbichler R, Forrest LR, Faraldo-Gómez J. Automated Protein-Insertion into Membranes for Molecular Dynamics Simulation Set-Up Using Taragrid Biophysical Journal. 98: 391a. DOI: 10.1016/J.Bpj.2009.12.2105 |
0.466 |
|
| 2009 |
Forrest LR, Rudnick G. The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters. Physiology (Bethesda, Md.). 24: 377-86. PMID 19996368 DOI: 10.1152/Physiol.00030.2009 |
0.464 |
|
| 2009 |
Crisman TJ, Qu S, Kanner BI, Forrest LR. Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats. Proceedings of the National Academy of Sciences of the United States of America. 106: 20752-7. PMID 19926849 DOI: 10.1073/Pnas.0908570106 |
0.472 |
|
| 2009 |
Tavoulari S, Forrest LR, Rudnick G. Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9635-43. PMID 19641126 DOI: 10.1523/Jneurosci.0440-09.2009 |
0.374 |
|
| 2009 |
Khafizov K, Ziegler C, Forrest L. Computational Studies of Substrate Binding and Conformational Change in the Glycine Betaine Symporter BetP Biophysical Journal. 96: 84a. DOI: 10.1016/J.Bpj.2008.12.338 |
0.51 |
|
| 2009 |
Forrest L, Zhang Y, Honig B, Rudnick G. A Role for Topologically-Inverted Structural Repeats in Secondary Active Transport by Membrane Proteins of the LeuT Fold Biophysical Journal. 96: 382a. DOI: 10.1016/J.Bpj.2008.12.2859 |
0.672 |
|
| 2008 |
Trötschel C, Follmann M, Nettekoven JA, Mohrbach T, Forrest LR, Burkovski A, Marin K, Krämer R. Methionine uptake in Corynebacterium glutamicum by MetQNI and by MetPS, a novel methionine and alanine importer of the NSS neurotransmitter transporter family Biochemistry. 47: 12698-12709. PMID 18991398 DOI: 10.1021/Bi801206T |
0.396 |
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| 2008 |
Forrest LR, Zhang YW, Jacobs MT, Gesmonde J, Xie L, Honig BH, Rudnick G. Mechanism for alternating access in neurotransmitter transporters. Proceedings of the National Academy of Sciences of the United States of America. 105: 10338-43. PMID 18647834 DOI: 10.1073/Pnas.0804659105 |
0.644 |
|
| 2008 |
Soto CS, Fasnacht M, Zhu J, Forrest L, Honig B. Loop modeling: Sampling, filtering, and scoring. Proteins. 70: 834-43. PMID 17729286 DOI: 10.1002/Prot.21612 |
0.72 |
|
| 2007 |
Hildebrand PW, Günther S, Goede A, Forrest L, Frömmel C, Preissner R. Hydrogen-bonding and packing features of membrane proteins: functional implications. Biophysical Journal. 94: 1945-53. PMID 17921213 DOI: 10.1529/Biophysj.107.110395 |
0.424 |
|
| 2007 |
Forrest LR, Tavoulari S, Zhang YW, Rudnick G, Honig B. Identification of a chloride ion binding site in Na+/Cl -dependent transporters. Proceedings of the National Academy of Sciences of the United States of America. 104: 12761-6. PMID 17652169 DOI: 10.1073/Pnas.0705600104 |
0.599 |
|
| 2007 |
Punta M, Forrest LR, Bigelow H, Kernytsky A, Liu J, Rost B. Membrane protein prediction methods Methods. 41: 460-474. PMID 17367718 DOI: 10.1016/J.Ymeth.2006.07.026 |
0.45 |
|
| 2006 |
Forrest LR, Tang CL, Honig B. On the accuracy of homology modeling and sequence alignment methods applied to membrane proteins. Biophysical Journal. 91: 508-17. PMID 16648166 DOI: 10.1529/Biophysj.106.082313 |
0.706 |
|
| 2005 |
Forrest LR, Honig B. An assessment of the accuracy of methods for predicting hydrogen positions in protein structures Proteins: Structure, Function and Genetics. 61: 296-309. PMID 16114036 DOI: 10.1002/Prot.20601 |
0.538 |
|
| 2004 |
Gimpelev M, Forrest LR, Murray D, Honig B. Helical packing patterns in membrane and soluble proteins. Biophysical Journal. 87: 4075-86. PMID 15465852 DOI: 10.1529/Biophysj.104.049288 |
0.724 |
|
| 2004 |
Faraldo-Gómez JD, Forrest LR, Baaden M, Bond PJ, Domene C, Patargias G, Cuthbertson J, Sansom MS. Conformational sampling and dynamics of membrane proteins from 10-nanosecond computer simulations. Proteins. 57: 783-91. PMID 15317024 DOI: 10.1002/Prot.20257 |
0.632 |
|
| 2003 |
Crozier PS, Stevens MJ, Forrest LR, Woolf TB. Molecular dynamics simulation of dark-adapted rhodopsin in an explicit membrane bilayer: coupling between local retinal and larger scale conformational change. Journal of Molecular Biology. 333: 493-514. PMID 14556740 DOI: 10.1016/J.Jmb.2003.08.045 |
0.622 |
|
| 2003 |
Forrest LR, Woolf TB. Discrimination of native loop conformations in membrane proteins: decoy library design and evaluation of effective energy scoring functions. Proteins. 52: 492-509. PMID 12910450 DOI: 10.1002/Prot.10404 |
0.661 |
|
| 2001 |
Cordes FS, Kukol A, Forrest LR, Arkin IT, Sansom MS, Fischer WB. The structure of the HIV-1 Vpu ion channel: modelling and simulation studies. Biochimica Et Biophysica Acta. 1512: 291-8. PMID 11406106 DOI: 10.1016/S0005-2736(01)00332-7 |
0.558 |
|
| 2000 |
Fischer WB, Pitkeathly M, Wallace BA, Forrest LR, Smith GR, Sansom MS. Transmembrane peptide NB of influenza B: a simulation, structure, and conductance study. Biochemistry. 39: 12708-16. PMID 11027151 DOI: 10.1021/Bi001000E |
0.514 |
|
| 2000 |
Schnick C, Forrest LR, Sansom MS, Groth G. Molecular contacts in the transmembrane c-subunit oligomer of F-ATPases identified by tryptophan substitution mutagenesis. Biochimica Et Biophysica Acta. 1459: 49-60. PMID 10924898 DOI: 10.1016/S0005-2728(00)00112-2 |
0.579 |
|
| 2000 |
Capener CE, Shrivastava IH, Ranatunga KM, Forrest LR, Smith GR, Sansom MS. Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel. Biophysical Journal. 78: 2929-42. PMID 10827973 DOI: 10.1016/S0006-3495(00)76833-0 |
0.552 |
|
| 2000 |
Fischer WB, Forrest LR, Smith GR, Sansom MS. Transmembrane domains of viral ion channel proteins: a molecular dynamics simulation study. Biopolymers. 53: 529-38. PMID 10766949 DOI: 10.1002/(Sici)1097-0282(200006)53:7<529::Aid-Bip1>3.0.Co;2-6 |
0.577 |
|
| 2000 |
Forrest LR, Sansom MS. Membrane simulations: Bigger and better? Current Opinion in Structural Biology. 10: 174-181. PMID 10753807 DOI: 10.1016/S0959-440X(00)00066-X |
0.601 |
|
| 2000 |
Law RJ, Forrest LR, Ranatunga KM, La Rocca P, Tieleman DP, Sansom MS. Structure and dynamics of the pore-lining helix of the nicotinic receptor: MD simulations in water, lipid bilayers, and transbilayer bundles. Proteins. 39: 47-55. PMID 10737926 DOI: 10.1002/(Sici)1097-0134(20000401)39:1<47::Aid-Prot5>3.0.Co;2-A |
0.564 |
|
| 2000 |
Shrivastava IH, Capener CE, Forrest LR, Sansom MS. Structure and dynamics of K channel pore-lining helices: a comparative simulation study. Biophysical Journal. 78: 79-92. PMID 10620275 DOI: 10.1016/S0006-3495(00)76574-X |
0.573 |
|
| 2000 |
Forrest LR, Kukol A, Arkin IT, Tieleman DP, Sansom MS. Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer. Biophysical Journal. 78: 55-69. PMID 10620273 DOI: 10.1016/S0006-3495(00)76572-6 |
0.549 |
|
| 1999 |
Forrest LR, Tieleman DP, Sansom MS. Defining the transmembrane helix of M2 protein from influenza A by molecular dynamics simulations in a lipid bilayer. Biophysical Journal. 76: 1886-96. PMID 10096886 DOI: 10.1016/S0006-3495(99)77347-9 |
0.595 |
|
| 1998 |
Sansom MS, Forrest LR, Bull R. Viral ion channels: molecular modeling and simulation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 992-1000. PMID 10048299 DOI: 10.1002/(Sici)1521-1878(199812)20:12<992::Aid-Bies5>3.0.Co;2-7 |
0.573 |
|
| 1998 |
Forrest LR, Degrado WF, Dieckmann GR, Sansom MSP. Two models of the influenza A M2 channel domain: Verification by comparison Folding and Design. 3: 443-448. PMID 9889158 DOI: 10.1016/S1359-0278(98)00061-3 |
0.47 |
|
| 1998 |
Tieleman DP, Forrest LR, Sansom MS, Berendsen HJ. Lipid properties and the orientation of aromatic residues in OmpF, influenza M2, and alamethicin systems: molecular dynamics simulations. Biochemistry. 37: 17554-61. PMID 9860871 DOI: 10.1021/Bi981802Y |
0.588 |
|
| 1998 |
Sansom MS, Tieleman DP, Forrest LR, Berendsen HJ. Molecular dynamics simulations of membranes with embedded proteins and peptides: porin, alamethicin and influenza virus M2. Biochemical Society Transactions. 26: 438-43. PMID 9765893 DOI: 10.1042/Bst0260438 |
0.538 |
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