Lucy Rachel Forrest - Publications

National Institutes of Health, Bethesda, MD 
Computational biology on membrane transporter proteins

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK. Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223522 DOI: 10.1073/pnas.1613293114  0.36
2017 Dayan O, Nagarajan A, Shah R, Ben-Yona A, Forrest LR, Kanner BI. An extra amino acid residue in transmembrane domain 10 of the GABA transporter GAT-1 is required for efficient ion-coupled transport. The Journal of Biological Chemistry. PMID 28213519 DOI: 10.1074/jbc.M117.775189  0.36
2016 Davis BA, Nagarajan A, Forrest LR, Singh SK. Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. Scientific Reports. 6: 23789. PMID 27032980 DOI: 10.1038/srep23789  1
2015 Tavoulari S, Margheritis E, Nagarajan A, DeWitt DC, Zhang YW, Rosado E, Ravera S, Rhoades E, Forrest LR, Rudnick G. Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog. The Journal of Biological Chemistry. PMID 26582198 DOI: 10.1074/Jbc.M115.692012  1
2015 Silverstein N, Ewers D, Forrest LR, Fahlke C, Kanner BI. Molecular Determinants of Substrate Specificity in Sodium-Coupled Glutamate Transporters. The Journal of Biological Chemistry. PMID 26475859 DOI: 10.1074/Jbc.M115.682666  1
2015 Stamm M, Forrest LR. Structure alignment of membrane proteins: Accuracy of available tools and a consensus strategy. Proteins. 83: 1720-32. PMID 26178143 DOI: 10.1002/prot.24857  1
2015 Forrest LR. Structural Symmetry in Membrane Proteins∗ Annual Review of Biophysics. 44: 311-337. PMID 26098517 DOI: 10.1146/annurev-biophys-051013-023008  1
2015 Fowler PW, Orwick-Rydmark M, Radestock S, Solcan N, Dijkman PM, Lyons JA, Kwok J, Caffrey M, Watts A, Forrest LR, Newstead S. Gating topology of the proton-coupled oligopeptide symporters. Structure (London, England : 1993). 23: 290-301. PMID 25651061 DOI: 10.1016/J.Str.2014.12.012  1
2015 Fenollar-Ferrer C, Forster IC, Patti M, Knoepfel T, Werner A, Forrest LR. Identification of the first sodium binding site of the phosphate cotransporter NaPi-IIa (SLC34A1) Biophysical Journal. 108: 2465-2480. DOI: 10.1016/j.bpj.2015.03.054  1
2014 Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S. Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). The Journal of Biological Chemistry. 289: 34229-40. PMID 25336661 DOI: 10.1074/Jbc.M114.607366  1
2014 Fenollar-Ferrer C, Stockner T, Schwarz TC, Pal A, Gotovina J, Hofmaier T, Jayaraman K, Adhikary S, Kudlacek O, Mehdipour AR, Tavoulari S, Rudnick G, Singh SK, Konrat R, Sitte HH, ... Forrest LR, et al. Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter. Biochemistry. 53: 5444-60. PMID 25093911 DOI: 10.1021/Bi500637F  1
2014 Fenollar-Ferrer C, Patti M, Knöpfel T, Werner A, Forster IC, Forrest LR. Structural fold and binding sites of the human Na⁺-phosphate cotransporter NaPi-II. Biophysical Journal. 106: 1268-79. PMID 24655502 DOI: 10.1016/j.bpj.2014.01.043  1
2013 Yaffe D, Radestock S, Shuster Y, Forrest LR, Schuldiner S. Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the United States of America. 110: E1332-41. PMID 23530208 DOI: 10.1073/Pnas.1220497110  1
2013 Forrest LR. (Pseudo-)symmetrical transport Science. 339: 399-401. PMID 23349276 DOI: 10.1126/science.1228465  1
2011 Radestock S, Forrest LR. The alternating-access mechanism of MFS transporters arises from inverted-topology repeats Journal of Molecular Biology. 407: 698-715. PMID 21315728 DOI: 10.1016/j.jmb.2011.02.008  1
2011 Tavoulari S, Rizwan AN, Forrest LR, Rudnick G. Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue. The Journal of Biological Chemistry. 286: 2834-42. PMID 21115480 DOI: 10.1074/Jbc.M110.186064  1
2009 Forrest LR, Rudnick G. The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters. Physiology (Bethesda, Md.). 24: 377-86. PMID 19996368 DOI: 10.1152/Physiol.00030.2009  1
2009 Tavoulari S, Forrest LR, Rudnick G. Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9635-43. PMID 19641126 DOI: 10.1523/Jneurosci.0440-09.2009  1
2008 Trötschel C, Follmann M, Nettekoven JA, Mohrbach T, Forrest LR, Burkovski A, Marin K, Krämer R. Methionine uptake in Corynebacterium glutamicum by MetQNI and by MetPS, a novel methionine and alanine importer of the NSS neurotransmitter transporter family Biochemistry. 47: 12698-12709. PMID 18991398 DOI: 10.1021/bi801206t  1
2008 Forrest LR, Zhang YW, Jacobs MT, Gesmonde J, Xie L, Honig BH, Rudnick G. Mechanism for alternating access in neurotransmitter transporters. Proceedings of the National Academy of Sciences of the United States of America. 105: 10338-43. PMID 18647834 DOI: 10.1073/Pnas.0804659105  1
2008 Soto CS, Fasnacht M, Zhu J, Forrest L, Honig B. Loop modeling: Sampling, filtering, and scoring. Proteins. 70: 834-43. PMID 17729286 DOI: 10.1002/Prot.21612  1
2007 Forrest LR, Tavoulari S, Zhang YW, Rudnick G, Honig B. Identification of a chloride ion binding site in Na+/Cl -dependent transporters. Proceedings of the National Academy of Sciences of the United States of America. 104: 12761-6. PMID 17652169 DOI: 10.1073/Pnas.0705600104  1
2007 Punta M, Forrest LR, Bigelow H, Kernytsky A, Liu J, Rost B. Membrane protein prediction methods Methods. 41: 460-474. PMID 17367718 DOI: 10.1016/J.Ymeth.2006.07.026  1
2006 Forrest LR, Tang CL, Honig B. On the accuracy of homology modeling and sequence alignment methods applied to membrane proteins. Biophysical Journal. 91: 508-17. PMID 16648166 DOI: 10.1529/Biophysj.106.082313  0.68
2005 Forrest LR, Honig B. An assessment of the accuracy of methods for predicting hydrogen positions in protein structures Proteins: Structure, Function and Genetics. 61: 296-309. PMID 16114036 DOI: 10.1002/Prot.20601  1
2004 Gimpelev M, Forrest LR, Murray D, Honig B. Helical packing patterns in membrane and soluble proteins. Biophysical Journal. 87: 4075-86. PMID 15465852 DOI: 10.1529/Biophysj.104.049288  1
2003 Crozier PS, Stevens MJ, Forrest LR, Woolf TB. Molecular dynamics simulation of dark-adapted rhodopsin in an explicit membrane bilayer: coupling between local retinal and larger scale conformational change. Journal of Molecular Biology. 333: 493-514. PMID 14556740 DOI: 10.1016/J.Jmb.2003.08.045  1
2003 Forrest LR, Woolf TB. Discrimination of native loop conformations in membrane proteins: decoy library design and evaluation of effective energy scoring functions. Proteins. 52: 492-509. PMID 12910450 DOI: 10.1002/prot.10404  1
2000 Schnick C, Forrest LR, Sansom MS, Groth G. Molecular contacts in the transmembrane c-subunit oligomer of F-ATPases identified by tryptophan substitution mutagenesis. Biochimica Et Biophysica Acta. 1459: 49-60. PMID 10924898 DOI: 10.1016/S0005-2728(00)00112-2  0.56
2000 Forrest LR, Sansom MS. Membrane simulations: Bigger and better? Current Opinion in Structural Biology. 10: 174-181. PMID 10753807 DOI: 10.1016/S0959-440X(00)00066-X  1
2000 Shrivastava IH, Capener CE, Forrest LR, Sansom MS. Structure and dynamics of K channel pore-lining helices: a comparative simulation study. Biophysical Journal. 78: 79-92. PMID 10620275 DOI: 10.1016/S0006-3495(00)76574-X  0.44
1998 Forrest LR, Degrado WF, Dieckmann GR, Sansom MSP. Two models of the influenza A M2 channel domain: Verification by comparison Folding and Design. 3: 443-448. PMID 9889158 DOI: 10.1016/S1359-0278(98)00061-3  1
1998 Forrest LR, Sansom MSP. Simulations of the M2 Channel for Influenza a Virus Biochemical Society Transactions. 26. PMID 9766022 DOI: 10.1042/BST026S303  1
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