Xu Ran - Related publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Drug Discovery
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 D'Annessa I, Hurwitz N, Pirota V, Beretta GL, Tinelli S, Woodford M, Freccero M, Mollapour M, Zaffaroni N, Wolfson H, Colombo G. Design of Disruptors of the Hsp90-Cdc37 Interface. Molecules (Basel, Switzerland). 25. PMID 31952296 DOI: 10.3390/molecules25020360   
2020 Kang C, Keller TH. Probing Biological Mechanisms with Chemical Tools. Pharmacological Research. 104656. PMID 31962154 DOI: 10.1016/j.phrs.2020.104656   
2020 Fratev F, Gutierrez DA, Aguilera RJ, Tyagi A, Damodaran C, Sirimulla S. Discovery of New AKT1 Inhibitors by Combination of Structure Based Virtual Screening Approaches and Biological Evaluations. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 31933423 DOI: 10.1080/07391102.2020.1715835   
2020 Kadonosono T, Yimchuen W, Ota Y, See K, Furuta T, Shiozawa T, Kitazawa M, Goto Y, Patil A, Kuchimaru T, Kizaka-Kondoh S. Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use. Scientific Reports. 10: 891. PMID 31964960 DOI: 10.1038/s41598-020-57713-4   
2020 Luo YS, Ferguson KC, Rusyn I, Chiu WA. In Vitro Bioavailability of the Hydrocarbon Fractions of Dimethyl Sulfoxide (DMSO) Extracts of Petroleum Substances. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32040194 DOI: 10.1093/toxsci/kfaa007   
2020 Hwang HY, Kim TY, Szász MA, Dome B, Malm J, Marko-Varga G, Kwon HJ. Profiling the Protein Targets of Unmodified Bio-Active Molecules with Drug Affinity Responsive Target Stability and Liquid Chromatography/Tandem Mass Spectrometry. Proteomics. e1900325. PMID 31926115 DOI: 10.1002/pmic.201900325   
2020 Akinjiyan FA, Fazal A, Hild M, Beckwith REJ, Ross NT, Paulk J, Carbonneau S. A Novel Luminescence-Based High-Throughput Approach for Cellular Resolution of Protein Ubiquitination Using Tandem Ubiquitin Binding Entities (TUBEs). Slas Discovery : Advancing Life Sciences R & D. 2472555219901261. PMID 31997692 DOI: 10.1177/2472555219901261   
2020 Dong G, He S, Qin X, Liu T, Jiang Y, Li X, Chen L, Han G, Sheng C, Li M. Discovery of Non-peptide, Environmental Sensitive Fluorescent Probes for Imaging p53-MDM2 Interaction in Living Cell Line and Tissue Slice. Analytical Chemistry. PMID 31918545 DOI: 10.1021/acs.analchem.9b04551   
2020 Kesari P, Pratap S, Dhankhar P, Dalal V, Mishra M, Singh PK, Chauhan H, Kumar P. Structural characterization and in-silico analysis of Momordica charantia 7S globulin for stability and ACE inhibition. Scientific Reports. 10: 1160. PMID 31980708 DOI: 10.1038/s41598-020-58138-9   
2020 Tong KC, Lok CN, Wan PK, Hu D, Fung YME, Chang XY, Huang S, Jiang H, Che CM. An anticancer gold(III)-activated porphyrin scaffold that covalently modifies protein cysteine thiols. Proceedings of the National Academy of Sciences of the United States of America. PMID 31896586 DOI: 10.1073/pnas.1915202117   
2020 Chen L, Lv D, Wang S, Wang D, Chen X, Liu Y, Hong Z, Zhu Z, Cao Y, Chai Y. An SPR-based membrane protein-targeted active ingredients recognition strategy: construction and implementation in ligand screening from herbal medicines. Analytical Chemistry. PMID 32045214 DOI: 10.1021/acs.analchem.9b05479   
2020 Cho KF, Ma TP, Rose CM, Kirkpatrick DS, Yu K, Blake RA. Chaperone mediated detection of small molecule target binding in cells. Nature Communications. 11: 465. PMID 31974362 DOI: 10.1038/s41467-019-14033-0   
2020 Pinto G, D'Acierno M, Illiano A, Petruk G, Ferraro G, Merlino A, Monti DM, Godovac-Zimmermann J, Amoresano A. Label-free quantitative proteomics of the MCF-7 cellular response to a ferritin-metallodrug complex. Molecular Omics. PMID 32016201 DOI: 10.1039/c9mo00158a   
2020 Bogner C, Kale J, Pogmore J, Chi X, Shamas-Din A, Fradin C, Leber B, Andrews DW. Allosteric Regulation of BH3 Proteins in Bcl-x Complexes Enables Switch-like Activation of Bax. Molecular Cell. PMID 32001105 DOI: 10.1016/j.molcel.2019.12.025   
2020 Abed DA, Lee S, Hu L. Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction. Bioorganic & Medicinal Chemistry. 115343. PMID 32046917 DOI: 10.1016/j.bmc.2020.115343   
2020 Notis Dardashti R, Kumar S, Sternisha S, Post SR, Miller BG, Metanis N. Selenolysine: a new tool for traceless isopeptide bond formation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31960982 DOI: 10.1002/chem.202000310   
2020 Gupta R, Leon F, Rauth S, Batra SK, Ponnusamy MP. A Systematic Review on the Implications of O-linked Glycan Branching and Truncating Enzymes on Cancer Progression and Metastasis. Cells. 9. PMID 32075174 DOI: 10.3390/cells9020446   
2020 Jena R, Garg DK, Achary MMV, Singh J, Tomar R, Choudhury L, Bansal R, Kundu B. Application of a protein domain as chaperone for enhancing biological activity and stability of other proteins. Journal of Biotechnology. PMID 32014561 DOI: 10.1016/j.jbiotec.2020.01.017   
2020 Zhou L, Li J, Zhang K, Shi L, Qin S, Li H. Electrochemical Cross-Linking and Cleavage Enables Molecular Gaping and Bridging on a Biosensing Surface. Analytical Chemistry. PMID 31927916 DOI: 10.1021/acs.analchem.9b04538   
2020 Kang J, Lee JY, Park JH, Chang DJ. Synthesis of imatinib, a tyrosine kinase inhibitor, labeled with carbon-14. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31975483 DOI: 10.1002/jlcr.3830   
2020 Zhang NN, Kang JS, Liu SS, Gu SM, Song ZP, Li FX, Wang LF, Yao L, Li T, Li LL, Wang Y, Li XJ, Mao XM. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Scientific Reports. 10: 439. PMID 31949205 DOI: 10.1038/s41598-019-57360-4   
2020 Inoue K, Mizuo H, Ishida T, Komori T, Kusano K. Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-35. PMID 32039641 DOI: 10.1080/00498254.2020.1728592   
2020 Gifre-Renom L, Seras-Franzoso J, Rafael D, Andrade F, Cano-Garrido O, Martinez-Trucharte F, Ugarte-Berzal E, Martens E, Boon L, Villaverde A, Opdenakker G, Schwartz S, Arís A, Garcia-Fruitós E. The Biological Potential Hidden in Inclusion Bodies. Pharmaceutics. 12. PMID 32075316 DOI: 10.3390/pharmaceutics12020157   
2020 Sengupta A, Liriano J, Miller BG, Frederich JH. Analysis of interactions stabilized by fusicoccin A reveals an expanded suite of potential 14-3-3 binding partners. Acs Chemical Biology. PMID 31971771 DOI: 10.1021/acschembio.9b00795   
2020 Cunningham JM, Koytiger G, Sorger PK, AlQuraishi M. Biophysical prediction of protein-peptide interactions and signaling networks using machine learning. Nature Methods. PMID 31907444 DOI: 10.1038/s41592-019-0687-1   
2020 O'Day DH, Taylor RJ, Myre MA. Calmodulin and Calmodulin Binding Proteins in : A Primer. International Journal of Molecular Sciences. 21. PMID 32054133 DOI: 10.3390/ijms21041210   
2020 Sandoval DR, Gomez Toledo A, Painter CD, Tota EM, Sheikh MO, West AMV, Frank MM, Wells L, Xu D, Bicknell R, Corbett KD, Esko JD. Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin binding protein. The Journal of Biological Chemistry. PMID 31964714 DOI: 10.1074/jbc.RA119.011639   
2020 Khurshid Y, Syed B, Simjee SU, Beg O, Ahmed A. Antiproliferative and apoptotic effects of proteins from black seeds (Nigella sativa) on human breast MCF-7 cancer cell line. Bmc Complementary Medicine and Therapies. 20: 5. PMID 32020890 DOI: 10.1186/s12906-019-2804-1   
2020 Chang J, Chen X, Wang R, Shi R, Wang X, Lu W, Ma S, Xia Q. High-Throughput Screening Identifies Two Novel Small Molecule Enhancers of Recombinant Protein Expression. Molecules (Basel, Switzerland). 25. PMID 31952231 DOI: 10.3390/molecules25020353   
2020 Liu M, Li N, Zhang Y, Zheng Z, Zhuo Y, Sun B, Bai LP, Zhang M, Guo MQ, Wu JL. Characterization of covalent protein modification by triclosan in vivo and in vitro via three-dimensional liquid chromatography-mass spectrometry: New insight into its adverse effects. Environment International. 136: 105423. PMID 32035293 DOI: 10.1016/j.envint.2019.105423   
2020 Martin ER, Barbieri A, Ford RC, Robinson RC. crystals reveal critical features of the interaction between CFTR and the PDZ2 domain of Na/H exchange cofactor NHERF1. The Journal of Biological Chemistry. PMID 32014995 DOI: 10.1074/jbc.RA119.012015   
2020 Hu T, Wu L, Sun X, Su P, Yang Y. Comparative study on quantitation of human myoglobin by both isotope dilution mass spectrometry and surface plasmon resonance based on calibration-free analysis. Analytical and Bioanalytical Chemistry. PMID 32076791 DOI: 10.1007/s00216-020-02504-z   
2020 Papachristodoulou M, Doutch J, Leung HSB, Church A, Charleston T, Clifton LA, Butler PD, Roberts CJ, Bracewell DG. In situ neutron scattering of antibody adsorption during protein A chromatography. Journal of Chromatography. A. 460842. PMID 31928770 DOI: 10.1016/j.chroma.2019.460842   
2020 Liang K, Chen H. Protein-based nanoplatforms for tumor imaging and therapy. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1616. PMID 31999083 DOI: 10.1002/wnan.1616   
2020 Liu X, Zurlo G, Zhang Q. The Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer. Advances in Experimental Medicine and Biology. 1217: 173-186. PMID 31898228 DOI: 10.1007/978-981-15-1025-0_11   
2020 Schuster J, Koulov A, Mahler HC, Detampel P, Huwyler J, Singh S, Mathaes R. In Vivo Stability of Therapeutic Proteins. Pharmaceutical Research. 37: 23. PMID 31900680 DOI: 10.1007/s11095-019-2689-1   
2020 Li C, Cao XW, Zhao J, Wang FJ. Effective Therapeutic Drug Delivery by GALA3, an Endosomal Escape Peptide with Reduced Hydrophobicity. The Journal of Membrane Biology. PMID 32002589 DOI: 10.1007/s00232-020-00109-2   
2020 Zhou H, Wang Y, You Q, Jiang Z. Recent progress in the development of small molecule Nrf2 activators: a patent review (2017-present). Expert Opinion On Therapeutic Patents. PMID 31922884 DOI: 10.1080/13543776.2020.1715365   
2020 Eshghi A, Pistawka AJ, Liu J, Chen M, Sinclair NJT, Hardie DB, Elliott M, Chen L, Newman R, Mohammed Y, Borchers CH. Concentration determination of >200 proteins in dried blood spots for biomarker discovery and validation. Molecular & Cellular Proteomics : McP. PMID 31896676 DOI: 10.1074/mcp.TIR119.001820   
2020 Kopylov AT, Stepanov AA, Malsagova KA, Soni D, Kushlinsky NE, Enikeev DV, Potoldykova NV, Lisitsa AV, Kaysheva AL. Revelation of Proteomic Indicators for Colorectal Cancer in Initial Stages of Development. Molecules (Basel, Switzerland). 25. PMID 32023884 DOI: 10.3390/molecules25030619   
2020 Reddy JM, Raut NGR, Seifert JL, Hynds DL. Regulation of Small GTPase Prenylation in the Nervous System. Molecular Neurobiology. PMID 31989383 DOI: 10.1007/s12035-020-01870-0   
2020 Golubeva VA, Nepomuceno TC, Gregoriis G, Mesquita RD, Li X, Dash S, Garcez PP, Suarez-Kurtz G, Izumi V, Koomen J, Carvalho MA, Monteiro ANA. Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins. Cells. 9. PMID 31936331 DOI: 10.3390/cells9010153   
2020 Ameer K, Chirom A, Paul A. Production and purification of anti-tubercular and anticancer protein from Staphylococcus hominis under mild stress condition of Mentha piperita L. Journal of Pharmaceutical and Biomedical Analysis. 182: 113136. PMID 32035335 DOI: 10.1016/j.jpba.2020.113136   
2020 Baek M, Martín-Gago P, Laursen JS, Madsen JLH, Chakladar S, Olsen CA. Photo Cross-linking Probes Containing ε-N-Thioacyllysine and ε-N-Acyl-(δ-aza)lysine Residues. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31922630 DOI: 10.1002/chem.201905338   
2020 Chen SW, Tan D, Yang YS, Zhang W. Investigation of the effect of salt additives in Protein L affinity chromatography for the purification of tandem single-chain variable fragment bispecific antibodies. Mabs. 12: 1718440. PMID 31983280 DOI: 10.1080/19420862.2020.1718440   
2020 Islam F, Gopalan V, Lam AK. Mass Spectrometry for Biomarkers Discovery in Esophageal Squamous Cell Carcinoma. Methods in Molecular Biology (Clifton, N.J.). 2129: 259-268. PMID 32056183 DOI: 10.1007/978-1-0716-0377-2_19   
2020 Cabrera A, Wiebelhaus N, Quan B, Ma R, Meng H, Fitzgerald MC. Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach. Journal of the American Society For Mass Spectrometry. 31: 217-226. PMID 32031398 DOI: 10.1021/jasms.9b00041   
2020 Perrin J, Werner T, Kurzawa N, Rutkowska A, Childs DD, Kalxdorf M, Poeckel D, Stonehouse E, Strohmer K, Heller B, Thomson DW, Krause J, Becher I, Eberl HC, Vappiani J, et al. Identifying drug targets in tissues and whole blood with thermal-shift profiling. Nature Biotechnology. PMID 31959954 DOI: 10.1038/s41587-019-0388-4   
2020 Wan F, Zhu Y, Hu H, Dai A, Cai X, Chen L, Gong H, Xia T, Yang D, Wang M, Zeng J. DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening. Genomics, Proteomics & Bioinformatics. PMID 32035227 DOI: 10.1016/j.gpb.2019.04.003   
2020 Wang Y, Zhang A, Wang Y, Wang X, Xu N, Jiang L. Effects of irradiation on the structure and properties of glycosylated soybean proteins. Food & Function. PMID 32025672 DOI: 10.1039/c9fo01879d