Erich A. Nigg - Publications

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241 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ganier O, Schnerch D, Nigg EA. Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion. Open Biology. 8. PMID 29899122 DOI: 10.1098/Rsob.180044  0.356
2018 Nigg EA, Schnerch D, Ganier O. Impact of Centrosome Aberrations on Chromosome Segregation and Tissue Architecture in Cancer. Cold Spring Harbor Symposia On Quantitative Biology. PMID 29610243 DOI: 10.1101/Sqb.2017.82.034421  0.393
2018 Ganier O, Schnerch D, Oertle P, Lim RY, Plodinec M, Nigg EA. Structural centrosome aberrations promote non-cell-autonomous invasiveness. The Embo Journal. PMID 29567643 DOI: 10.15252/Embj.201798576  0.396
2018 Viganó C, von Schubert C, Ahrné E, Schmidt A, Lorber T, Bubendorf L, De Vetter JRF, Zaman GJR, Storchova Z, Nigg EA. Quantitative proteomic and phospho-proteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability. Molecular Biology of the Cell. PMID 29496963 DOI: 10.1091/Mbc.E17-10-0577  0.417
2018 Arquint C, Cubizolles F, Morand A, Schmidt A, Nigg EA. The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number. Open Biology. 8. PMID 29445034 DOI: 10.1098/Rsob.170253  0.387
2018 Nigg EA, Holland AJ. Once and only once: mechanisms of centriole duplication and their deregulation in disease. Nature Reviews. Molecular Cell Biology. PMID 29363672 DOI: 10.1038/Nrm.2017.127  0.389
2017 Pitchai GP, Kaulich M, Bizard AH, Mesa P, Yao Q, Sarlos K, Streicher WW, Nigg EA, Montoya G, Hickson ID. A novel TPR-BEN domain interaction mediates PICH-BEND3 association. Nucleic Acids Research. PMID 28977671 DOI: 10.1093/Nar/Gkx792  0.383
2017 Domingues PH, Nanduri LS, Seget K, Venkateswaran SV, Agorku D, Viganó C, von Schubert C, Nigg EA, Swanton C, Sotillo R, Bosio A, Storchová Z, Hardt O. Cellular prion protein PRPC and ecto-5'-nucleotidase are markers of the cellular stress response to aneuploidy. Cancer Research. PMID 28377454 DOI: 10.1158/0008-5472.Can-16-3052  0.33
2017 Fava LL, Schuler F, Sladky V, Haschka MD, Soratroi C, Eiterer L, Demetz E, Weiss G, Geley S, Nigg EA, Villunger A. The PIDDosome activates p53 in response to supernumerary centrosomes. Genes & Development. 31: 34-45. PMID 28130345 DOI: 10.1101/Gad.289728.116  0.403
2016 Arquint C, Nigg EA. The PLK4-STIL-SAS-6 module at the core of centriole duplication. Biochemical Society Transactions. 44: 1253-1263. PMID 27911707 DOI: 10.1042/Bst20160116  0.457
2016 Redli PM, Gasic I, Meraldi P, Nigg EA, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. The Journal of Cell Biology. 215: 77-93. PMID 27697923 DOI: 10.1083/Jcb.201603019  0.432
2016 Abad MA, Zou J, Medina-Pritchard B, Nigg EA, Rappsilber J, Santamaria A, Jeyaprakash AA. Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain. Scientific Reports. 6: 34042. PMID 27667719 DOI: 10.1038/Srep34042  0.395
2016 Bauer M, Cubizolles F, Schmidt A, Nigg EA. Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging. The Embo Journal. PMID 27539480 DOI: 10.15252/Embj.201694462  0.42
2016 Baron AP, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schröder J, Fernández-Montalván A, von Nussbaum F, Mumberg D, Nigg EA. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 5. PMID 26885717 DOI: 10.7554/Elife.12187  0.502
2016 Schnerch D, Nigg EA. Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres Oncogene. 35: 2711-2722. PMID 26364601 DOI: 10.1038/Onc.2015.332  0.371
2016 Baron AP, Schubert Cv, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schröder J, Fernández-Montalván A, Nussbaum Fv, Mumberg D, Nigg EA. Author response: Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524 Elife. DOI: 10.7554/Elife.12187.022  0.35
2016 Baron AP, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schroder J, Fernández-Montalván A, von Nussbaum F, Mumberg D, Nigg EA. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524 Elife. 5. DOI: 10.7554/eLife.12187  0.403
2016 Baron AP, Schubert Cv, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schröder J, Fernández-Montalván A, Lange M, Nussbaum Fv, Mumberg D, Nigg E. Abstract 2725: Probing mitotic functions of BUB1 kinase using the small molecule inhibitors BAY-320 and BAY-524 Cancer Research. 76: 2725-2725. DOI: 10.1158/1538-7445.Am2016-2725  0.496
2015 Nielsen CF, Huttner D, Bizard AH, Hirano S, Li TN, Palmai-Pallag T, Bjerregaard VA, Liu Y, Nigg EA, Wang LH, Hickson ID. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nature Communications. 6: 8962. PMID 26643143 DOI: 10.1038/Ncomms9962  0.396
2015 Ittig SJ, Schmutz C, Kasper CA, Amstutz M, Schmidt A, Sauteur L, Vigano MA, Low SH, Affolter M, Cornelis GR, Nigg EA, Arrieumerlou C. A bacterial type III secretion-based protein delivery tool for broad applications in cell biology. The Journal of Cell Biology. 211: 913-31. PMID 26598622 DOI: 10.1083/Jcb.201502074  0.363
2015 Bauer M, Ahrné E, Baron AP, Glatter T, Fava LL, Santamaria A, Nigg EA, Schmidt A. Assessment of current mass spectrometric workflows for the quantification of low abundant proteins and phosphorylation sites. Data in Brief. 5: 297-304. PMID 26550600 DOI: 10.1016/J.Dib.2015.08.015  0.375
2015 Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg EA, Elowe S. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nature Communications. 6: 8364. PMID 26399325 DOI: 10.1038/Ncomms9364  0.456
2015 Arquint C, Gabryjonczyk AM, Imseng S, Böhm R, Sauer E, Hiller S, Nigg EA, Maier T. STIL binding to Polo-box 3 of PLK4 regulates centriole duplication. Elife. 4. PMID 26188084 DOI: 10.7554/Elife.07888  0.418
2015 von Schubert C, Cubizolles F, Bracher JM, Sliedrecht T, Kops GJPL, Nigg EA. Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells. Cell Reports. 12: 66-78. PMID 26119734 DOI: 10.1016/J.Celrep.2015.06.007  0.534
2015 Floriot S, Vesque C, Rodriguez S, Bourgain-Guglielmetti F, Karaiskou A, Gautier M, Duchesne A, Barbey S, Fritz S, Vasilescu A, Bertaud M, Moudjou M, Halliez S, Cormier-Daire V, E L Hokayem J, ... Nigg EA, et al. C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle. Nature Communications. 6: 6894. PMID 25902731 DOI: 10.1038/Ncomms7894  0.31
2015 Čajánek L, Glatter T, Nigg EA. The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis. Journal of Cell Science. 128: 1674-82. PMID 25795303 DOI: 10.1242/Jcs.166496  0.432
2015 Boehm R, Arquint C, Gabryjonczyk A, Imseng S, Sauer E, Nigg E, Maier T, Hiller S. STIL binding to the Polo-box 3 of PLK4 regulates centriole duplication - Backbone assignment of human Polo-box 3 bound to STIL Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr26547  0.314
2014 Bauer M, Ahrné E, Baron AP, Glatter T, Fava LL, Santamaria A, Nigg EA, Schmidt A. Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites. Journal of Proteome Research. 13: 5973-88. PMID 25330945 DOI: 10.1021/Pr500860C  0.32
2014 Arquint C, Gabryjonczyk AM, Nigg EA. Centrosomes as signalling centres. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25047618 DOI: 10.1098/Rstb.2013.0464  0.37
2014 Čajánek L, Nigg EA. Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole. Proceedings of the National Academy of Sciences of the United States of America. 111: E2841-50. PMID 24982133 DOI: 10.1073/Pnas.1401777111  0.506
2014 Nigg EA, Čajánek L, Arquint C. The centrosome duplication cycle in health and disease. Febs Letters. 588: 2366-72. PMID 24951839 DOI: 10.1016/J.Febslet.2014.06.030  0.438
2014 Abad MA, Medina B, Santamaria A, Zou J, Plasberg-Hill C, Madhumalar A, Jayachandran U, Redli PM, Rappsilber J, Nigg EA, Jeyaprakash AA. Structural basis for microtubule recognition by the human kinetochore Ska complex. Nature Communications. 5: 2964. PMID 24413531 DOI: 10.1038/Ncomms3964  0.373
2013 Bhogaraju S, Cajanek L, Fort C, Blisnick T, Weber K, Taschner M, Mizuno N, Lamla S, Bastin P, Nigg EA, Lorentzen E. Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (New York, N.Y.). 341: 1009-12. PMID 23990561 DOI: 10.1126/Science.1240985  0.368
2013 Nunes Bastos R, Gandhi SR, Baron RD, Gruneberg U, Nigg EA, Barr FA. Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. The Journal of Cell Biology. 202: 605-21. PMID 23940115 DOI: 10.1083/Jcb.201301094  0.452
2013 Kasahara K, Goto H, Izawa I, Kiyono T, Watanabe N, Elowe S, Nigg EA, Inagaki M. PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition. Nature Communications. 4: 1882. PMID 23695676 DOI: 10.1038/Ncomms2879  0.496
2013 Sonnen KF, Gabryjonczyk AM, Anselm E, Stierhof YD, Nigg EA. Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. Journal of Cell Science. 126: 3223-33. PMID 23641073 DOI: 10.1242/Jcs.129502  0.464
2013 von Schubert C, Nigg EA. Polo-like kinases. Current Biology : Cb. 23: R225-7. PMID 23518048 DOI: 10.1016/J.Cub.2013.01.066  0.556
2012 Holland AJ, Fachinetti D, Zhu Q, Bauer M, Verma IM, Nigg EA, Cleveland DW. The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes & Development. 26: 2684-9. PMID 23249732 DOI: 10.1101/Gad.207027.112  0.466
2012 Sonnen KF, Schermelleh L, Leonhardt H, Nigg EA. 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biology Open. 1: 965-76. PMID 23213374 DOI: 10.1242/Bio.20122337  0.42
2012 Kleylein-Sohn J, Pöllinger B, Ohmer M, Hofmann F, Nigg EA, Hemmings BA, Wartmann M. Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET. Journal of Cell Science. 125: 5391-402. PMID 22946058 DOI: 10.1242/Jcs.107474  0.384
2012 Kaulich M, Cubizolles F, Nigg EA. On the regulation, function, and localization of the DNA-dependent ATPase PICH. Chromosoma. 121: 395-408. PMID 22527115 DOI: 10.1007/S00412-012-0370-0  0.47
2012 Jeyaprakash AA, Santamaria A, Jayachandran U, Chan YW, Benda C, Nigg EA, Conti E. Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface Molecular Cell. 46: 274-286. PMID 22483620 DOI: 10.1016/J.Molcel.2012.03.005  0.403
2012 Rojas AM, Santamaria A, Malik R, Jensen TS, Körner R, Morilla I, de Juan D, Krallinger M, Hansen DA, Hoffmann R, Lees J, Reid A, Yeats C, Wehner A, Elowe S, ... ... Nigg EA, et al. Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology. Plos One. 7: e31813. PMID 22427808 DOI: 10.1371/Journal.Pone.0031813  0.384
2012 Chan YW, Jeyaprakash AA, Nigg EA, Santamaria A. Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. The Journal of Cell Biology. 196: 563-71. PMID 22371557 DOI: 10.1083/Jcb.201109001  0.366
2012 Arquint C, Sonnen KF, Stierhof YD, Nigg EA. Cell-cycle-regulated expression of STIL controls centriole number in human cells. Journal of Cell Science. 125: 1342-52. PMID 22349698 DOI: 10.1242/Jcs.099887  0.485
2012 Fairley JA, Mitchell LE, Berg T, Kenneth NS, von Schubert C, Silljé HH, Medema RH, Nigg EA, White RJ. Direct regulation of tRNA and 5S rRNA gene transcription by Polo-like kinase 1. Molecular Cell. 45: 541-52. PMID 22281053 DOI: 10.1016/J.Molcel.2011.11.030  0.454
2012 Fairley JA, Mitchell LE, Berg T, Kenneth NS, von Schubert C, Silljé HHW, Medema RH, Nigg EA, White RJ. Direct Regulation of tRNA and 5S rRNA Gene Transcription by Polo-like Kinase 1 Molecular Cell. 47: 148-149. DOI: 10.1016/J.Molcel.2012.06.022  0.38
2011 Nigg EA, Stearns T. The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nature Cell Biology. 13: 1154-60. PMID 21968988 DOI: 10.1038/Ncb2345  0.431
2011 Fava LL, Kaulich M, Nigg EA, Santamaria A. Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. The Embo Journal. 30: 3322-36. PMID 21772247 DOI: 10.1038/Emboj.2011.239  0.408
2011 Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JRA, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, et al. Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling Science Signaling. 4. PMID 21712545 DOI: 10.1126/Scisignal.2001796  0.49
2011 Dou Z, von Schubert C, Körner R, Santamaria A, Elowe S, Nigg EA. Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1. Plos One. 6: e18793. PMID 21533207 DOI: 10.1371/Journal.Pone.0018793  0.506
2011 Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. The Embo Journal. 30: 1520-35. PMID 21399614 DOI: 10.1038/Emboj.2011.63  0.423
2011 Santamaria A, Wang B, Elowe S, Malik R, Zhang F, Bauer M, Schmidt A, Silljé HH, Körner R, Nigg EA. The Plk1-dependent phosphoproteome of the early mitotic spindle. Molecular & Cellular Proteomics : McP. 10: M110.004457. PMID 20860994 DOI: 10.1074/Mcp.M110.004457  0.541
2010 von Schubert C, Xue G, Schmuckli-Maurer J, Woods KL, Nigg EA, Dobbelaere DA. The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. Plos Biology. 8. PMID 20927361 DOI: 10.1371/Journal.Pbio.1000499  0.414
2010 Guderian G, Westendorf J, Uldschmid A, Nigg EA. Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation. Journal of Cell Science. 123: 2163-9. PMID 20516151 DOI: 10.1242/Jcs.068502  0.535
2010 Wang LH, Mayer B, Stemmann O, Nigg EA. Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. Journal of Cell Science. 123: 806-13. PMID 20144989 DOI: 10.1242/Jcs.058255  0.34
2010 Dulla K, Daub H, Hornberger R, Nigg EA, Körner R. Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Molecular & Cellular Proteomics : McP. 9: 1167-81. PMID 20097925 DOI: 10.1074/Mcp.M900335-Mcp200  0.51
2010 Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Science Signaling. 3: ra3. PMID 20068231 DOI: 10.1126/Scisignal.2000475  0.536
2010 Elowe S, Dulla K, Uldschmid A, Li X, Dou Z, Nigg EA. Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. Journal of Cell Science. 123: 84-94. PMID 20016069 DOI: 10.1242/Jcs.056507  0.427
2010 Hübner NC, Wang LH, Kaulich M, Descombes P, Poser I, Nigg EA. Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma. 119: 149-65. PMID 19904549 DOI: 10.1007/S00412-009-0244-2  0.451
2009 Nigg EA, Raff JW. Centrioles, centrosomes, and cilia in health and disease. Cell. 139: 663-78. PMID 19914163 DOI: 10.1016/J.Cell.2009.10.036  0.315
2009 Klein UR, Nigg EA. SUMO-dependent regulation of centrin-2. Journal of Cell Science. 122: 3312-21. PMID 19706679 DOI: 10.1242/Jcs.050245  0.422
2009 Malik R, Lenobel R, Santamaria A, Ries A, Nigg EA, Körner R. Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. Journal of Proteome Research. 8: 4553-63. PMID 19691289 DOI: 10.1021/Pr9003773  0.499
2009 Schmidt TI, Kleylein-Sohn J, Westendorf J, Le Clech M, Lavoie SB, Stierhof YD, Nigg EA. Control of centriole length by CPAP and CP110. Current Biology : Cb. 19: 1005-11. PMID 19481458 DOI: 10.1016/J.Cub.2009.05.016  0.424
2009 Chan YW, Fava LL, Uldschmid A, Schmitz MH, Gerlich DW, Nigg EA, Santamaria A. Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. The Journal of Cell Biology. 185: 859-74. PMID 19468067 DOI: 10.1083/Jcb.200812167  0.453
2009 Gaitanos TN, Santamaria A, Jeyaprakash AA, Wang B, Conti E, Nigg EA. Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. The Embo Journal. 28: 1442-52. PMID 19360002 DOI: 10.1038/Emboj.2009.96  0.375
2009 Klein UR, Haindl M, Nigg EA, Muller S. RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Molecular Biology of the Cell. 20: 410-8. PMID 18946085 DOI: 10.1091/Mbc.E08-05-0511  0.473
2008 Wang B, Malik R, Nigg EA, Körner R. Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. Analytical Chemistry. 80: 9526-33. PMID 19007248 DOI: 10.1021/Ac801708P  0.407
2008 Chan EH, Santamaria A, Silljé HH, Nigg EA. Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma. 117: 457-69. PMID 18521620 DOI: 10.1007/S00412-008-0165-5  0.541
2008 Santamaria A, Nagel S, Sillje HHW, Nigg EA. The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle. Current Biology : Cb. 18: 723-729. PMID 18485706 DOI: 10.1016/J.Cub.2008.04.041  0.441
2008 Malik R, Nigg EA, Körner R. Comparative conservation analysis of the human mitotic phosphoproteome. Bioinformatics (Oxford, England). 24: 1426-32. PMID 18426804 DOI: 10.1093/Bioinformatics/Btn197  0.425
2008 Wang LH, Schwarzbraun T, Speicher MR, Nigg EA. Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma. 117: 123-35. PMID 17989990 DOI: 10.1007/S00412-007-0131-7  0.429
2007 Graser S, Stierhof YD, Nigg EA. Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. Journal of Cell Science. 120: 4321-31. PMID 18042621 DOI: 10.1242/Jcs.020248  0.434
2007 Jeyaprakash AA, Klein UR, Lindner D, Ebert J, Nigg EA, Conti E. Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell. 131: 271-85. PMID 17956729 DOI: 10.1016/J.Cell.2007.07.045  0.422
2007 Graser S, Stierhof YD, Lavoie SB, Gassner OS, Lamla S, Le Clech M, Nigg EA. Cep164, a novel centriole appendage protein required for primary cilium formation. The Journal of Cell Biology. 179: 321-30. PMID 17954613 DOI: 10.1083/Jcb.200707181  0.378
2007 Elowe S, Hümmer S, Uldschmid A, Li X, Nigg EA. Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes & Development. 21: 2205-19. PMID 17785528 DOI: 10.1101/Gad.436007  0.508
2007 Kleylein-Sohn J, Westendorf J, Le Clech M, Habedanck R, Stierhof YD, Nigg EA. Plk4-induced centriole biogenesis in human cells. Developmental Cell. 13: 190-202. PMID 17681131 DOI: 10.1016/J.Devcel.2007.07.002  0.417
2007 Santamaria A, Neef R, Eberspächer U, Eis K, Husemann M, Mumberg D, Prechtl S, Schulze V, Siemeister G, Wortmann L, Barr FA, Nigg EA. Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Molecular Biology of the Cell. 18: 4024-36. PMID 17671160 DOI: 10.1091/Mbc.E07-05-0517  0.512
2007 Thein KH, Kleylein-Sohn J, Nigg EA, Gruneberg U. Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. The Journal of Cell Biology. 178: 345-54. PMID 17664331 DOI: 10.1083/Jcb.200701163  0.45
2007 Nigg EA. Centrosome duplication: of rules and licenses. Trends in Cell Biology. 17: 215-21. PMID 17383880 DOI: 10.1016/J.Tcb.2007.03.003  0.491
2007 Neef R, Gruneberg U, Kopajtich R, Li X, Nigg EA, Sillje H, Barr FA. Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nature Cell Biology. 9: 436-44. PMID 17351640 DOI: 10.1038/Ncb1557  0.502
2007 Hergovich A, Lamla S, Nigg EA, Hemmings BA. Centrosome-associated NDR kinase regulates centrosome duplication. Molecular Cell. 25: 625-34. PMID 17317633 DOI: 10.1016/J.Molcel.2007.01.020  0.513
2007 Baumann C, Körner R, Hofmann K, Nigg EA. PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell. 128: 101-14. PMID 17218258 DOI: 10.1016/J.Cell.2006.11.041  0.448
2006 Hanisch A, Silljé HH, Nigg EA. Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. The Embo Journal. 25: 5504-15. PMID 17093495 DOI: 10.1038/Sj.Emboj.7601426  0.44
2006 Nigg EA. Origins and consequences of centrosome aberrations in human cancers. International Journal of Cancer. 119: 2717-23. PMID 17016823 DOI: 10.1002/Ijc.22245  0.313
2006 Nigg EA. Cell biology: a licence for duplication. Nature. 442: 874-5. PMID 16929283 DOI: 10.1038/442874A  0.347
2006 Chalamalasetty RB, Hümmer S, Nigg EA, Silljé HH. Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission. Journal of Cell Science. 119: 3008-19. PMID 16803869 DOI: 10.1242/Jcs.03032  0.499
2006 Mikolajka A, Yan X, Popowicz GM, Smialowski P, Nigg EA, Holak TA. Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. Journal of Molecular Biology. 359: 863-75. PMID 16690081 DOI: 10.1016/J.Jmb.2006.03.070  0.379
2006 Sayer JA, Otto EA, O'Toole JF, Nurnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, ... ... Nigg EA, et al. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nature Genetics. 38: 674-81. PMID 16682973 DOI: 10.1038/Ng1786  0.329
2006 Silljé HH, Nagel S, Körner R, Nigg EA. HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Current Biology : Cb. 16: 731-42. PMID 16631580 DOI: 10.1016/J.Cub.2006.02.070  0.422
2006 Badouel C, Körner R, Frank-Vaillant M, Couturier A, Nigg EA, Tassan JP. M-phase MELK activity is regulated by MPF and MAPK. Cell Cycle (Georgetown, Tex.). 5: 883-9. PMID 16628004 DOI: 10.4161/Cc.5.8.2683  0.42
2006 Klein UR, Nigg EA, Gruneberg U. Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Molecular Biology of the Cell. 17: 2547-58. PMID 16571674 DOI: 10.1091/Mbc.E05-12-1133  0.451
2006 Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R. Phosphoproteome analysis of the human mitotic spindle. Proceedings of the National Academy of Sciences of the United States of America. 103: 5391-6. PMID 16565220 DOI: 10.1073/Pnas.0507066103  0.536
2006 Schmidt A, Rauh NR, Nigg EA, Mayer TU. Cytostatic factor: an activity that puts the cell cycle on hold. Journal of Cell Science. 119: 1213-8. PMID 16554437 DOI: 10.1242/Jcs.02919  0.421
2006 Gruneberg U, Neef R, Li X, Chan EH, Chalamalasetty RB, Nigg EA, Barr FA. KIF14 and citron kinase act together to promote efficient cytokinesis. The Journal of Cell Biology. 172: 363-72. PMID 16431929 DOI: 10.1083/Jcb.200511061  0.458
2006 Tachibana KE, Nigg EA. Geminin regulates multiple steps of the chromosome inheritance cycle. Cell Cycle (Georgetown, Tex.). 5: 151-4. PMID 16397411 DOI: 10.4161/Cc.5.2.2363  0.408
2006 Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA, Inagaki M. Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nature Cell Biology. 8: 180-7. PMID 16378098 DOI: 10.1038/Ncb1350  0.537
2006 Silljé HHW, Nigg EA. Purification of mitotic spindles from cultured human cells Methods. 38: 25-28. PMID 16343935 DOI: 10.1016/J.Ymeth.2005.07.006  0.416
2006 Hanisch A, Wehner A, Nigg EA, Silljé HH. Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Molecular Biology of the Cell. 17: 448-59. PMID 16267267 DOI: 10.1091/Mbc.E05-08-0801  0.453
2005 Yan X, Habedanck R, Nigg EA. A Complex of Two Centrosomal Proteins, CAP350 and FOP, Cooperates with EB1 in Microtubule Anchoring Molecular Biology of the Cell. 17: 634-644. PMID 16314388 DOI: 10.1091/Mbc.E05-08-0810  0.433
2005 Yamaguchi T, Goto H, Yokoyama T, Silljé H, Hanisch A, Uldschmid A, Takai Y, Oguri T, Nigg EA, Inagaki M. Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis Journal of Cell Biology. 171: 431-436. PMID 16260496 DOI: 10.1083/Jcb.200504091  0.504
2005 Casenghi M, Barr FA, Nigg EA. Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. Journal of Cell Science. 118: 5101-5108. PMID 16254247 DOI: 10.1242/Jcs.02622  0.531
2005 Habedanck R, Stierhof Y, Wilkinson CJ, Nigg EA. The Polo kinase Plk4 functions in centriole duplication Nature Cell Biology. 7: 1140-1146. PMID 16244668 DOI: 10.1038/Ncb1320  0.493
2005 Bahe S, Stierhof Y, Wilkinson CJ, Leiss F, Nigg EA. Rootletin forms centriole-associated filaments and functions in centrosome cohesion Journal of Cell Biology. 171: 27-33. PMID 16203858 DOI: 10.1083/Jcb.200504107  0.458
2005 Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, Khanna KK. Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental Cell. 9: 477-88. PMID 16198290 DOI: 10.1016/J.Devcel.2005.09.003  0.542
2005 Tachibana KK, Gonzalez MA, Guarguaglini G, Nigg EA, Laskey RA. Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects Embo Reports. 6: 1052-1057. PMID 16179947 DOI: 10.1038/Sj.Embor.7400527  0.481
2005 Rauh NR, Schmidt A, Bormann J, Nigg EA, Mayer TU. Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature. 437: 1048-52. PMID 16127448 DOI: 10.1038/Nature04093  0.407
2005 Schmidt A, Duncan PI, Rauh NR, Sauer G, Fry AM, Nigg EA, Mayer TU. Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes & Development. 19: 502-13. PMID 15713843 DOI: 10.1101/Gad.320705  0.402
2005 Chan EH, Nousiainen M, Chalamalasetty RB, Schäfer A, Nigg EA, Silljé HH. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene. 24: 2076-86. PMID 15688006 DOI: 10.1038/Sj.Onc.1208445  0.518
2005 Rapley J, Baxter JE, Blot J, Wattam SL, Casenghi M, Meraldi P, Nigg EA, Fry AM. Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Molecular and Cellular Biology. 25: 1309-24. PMID 15684383 DOI: 10.1128/Mcb.25.4.1309-1324.2005  0.55
2005 Guarguaglini G, Duncan PI, Stierhof YD, Holmström T, Duensing S, Nigg EA. The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular Biology of the Cell. 16: 1095-107. PMID 15616186 DOI: 10.1091/Mbc.E04-10-0939  0.533
2005 Sauer G, Körner R, Hanisch A, Ries A, Nigg EA, Silljé HHW. Proteome Analysis of the Human Mitotic Spindle Molecular & Cellular Proteomics. 4: 35-43. PMID 15561729 DOI: 10.1074/Mcp.M400158-Mcp200  0.466
2004 Sasai K, Katayama H, Stenoien DL, Fujii S, Honda R, Kimura M, Okano Y, Tatsuka M, Suzuki F, Nigg EA, Earnshaw WC, Brinkley WR, Sen S. Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motility and the Cytoskeleton. 59: 249-63. PMID 15499654 DOI: 10.1002/Cm.20039  0.482
2004 Fletcher L, Cerniglia GJ, Nigg EA, Yend TJ, Muschel RJ. Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiation Research. 162: 128-35. PMID 15387139 DOI: 10.1667/Rr3211  0.37
2004 Krämer A, Mailand N, Lukas C, Syljuåsen RG, Wilkinson CJ, Nigg EA, Bartek J, Lukas J. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nature Cell Biology. 6: 884-91. PMID 15311285 DOI: 10.1038/Ncb1165  0.496
2004 Mishima M, Pavicic V, Grüneberg U, Nigg EA, Glotzer M. Cell cycle regulation of central spindle assembly. Nature. 430: 908-13. PMID 15282614 DOI: 10.1038/Nature02767  0.5
2004 Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA. Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2 Journal of Cell Biology. 166: 167-172. PMID 15263015 DOI: 10.1083/Jcb.200403084  0.504
2004 Gassmann R, Carvalho A, Henzing AJ, Ruchaud S, Hudson DF, Honda R, Nigg EA, Gerloff DL, Earnshaw WC. Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. The Journal of Cell Biology. 166: 179-91. PMID 15249581 DOI: 10.1083/Jcb.200404001  0.45
2004 Stucke VM, Baumann C, Nigg EA. Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma. 113: 1-15. PMID 15235793 DOI: 10.1007/S00412-004-0288-2  0.544
2004 Barr FA, Silljé HHW, Nigg EA. Polo-like kinases and the orchestration of cell division. Nature Reviews Molecular Cell Biology. 5: 429-440. PMID 15173822 DOI: 10.1038/Nrm1401  0.513
2004 Steensgaard P, Garrè M, Muradore I, Transidico P, Nigg EA, Kitagawa K, Earnshaw WC, Faretta M, Musacchio A. Sgt1 is required for human kinetochore assembly. Embo Reports. 5: 626-31. PMID 15133482 DOI: 10.1038/Sj.Embor.7400154  0.446
2004 Meraldi P, Honda R, Nigg EA. Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Current Opinion in Genetics & Development. 14: 29-36. PMID 15108802 DOI: 10.1016/J.Gde.2003.11.006  0.516
2003 Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M. Proteomic characterization of the human centrosome by protein correlation profiling Nature. 426: 570-574. PMID 14654843 DOI: 10.1038/Nature02166  0.441
2003 Kufer TA, Nigg EA, Silljé HHW. Regulation of Aurora-A kinase on the mitotic spindle Chromosoma. 112: 159-163. PMID 14634755 DOI: 10.1007/S00412-003-0265-1  0.562
2003 Cheng KY, Lowe ED, Sinclair J, Nigg EA, Johnson LN. The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. The Embo Journal. 22: 5757-68. PMID 14592974 DOI: 10.1093/Emboj/Cdg558  0.392
2003 Carrera P, Moshkin YM, Gronke S, Sillje HH, Nigg EA, Jackle H, Karch F. Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes & Development. 17: 2578-90. PMID 14561777 DOI: 10.1101/Gad.276703  0.522
2003 Krause DR, Jonnalagadda JC, Gatei MH, Sillje HHW, Zhou BB, Nigg EA, Khanna K. Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1 Oncogene. 22: 5927-5937. PMID 12955071 DOI: 10.1038/Sj.Onc.1206691  0.435
2003 Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. The Journal of Cell Biology. 162: 863-75. PMID 12939256 DOI: 10.1083/Jcb.200306009  0.536
2003 Honda R, Körner R, Nigg EA. Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Molecular Biology of the Cell. 14: 3325-3341. PMID 12925766 DOI: 10.1091/Mbc.E02-11-0769  0.473
2003 Casenghi M, Meraldi P, Weinhart U, Duncan PI, Körner R, Nigg EA. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Developmental Cell. 5: 113-25. PMID 12852856 DOI: 10.1016/S1534-5807(03)00193-X  0.54
2003 Gruneberg U, Nigg EA. Regulation of cell division : stop the SIN! Trends in Cell Biology. 13: 159-162. PMID 12667751 DOI: 10.1016/S0962-8924(03)00034-5  0.472
2003 Groth A, Lukas J, Nigg EA, Silljé HHW, Wernstedt C, Bartek J, Hansen K. Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. The Embo Journal. 22: 1676-1687. PMID 12660173 DOI: 10.1093/Emboj/Cdg151  0.397
2003 Silljé HHW, Nigg EA. Capturing polo kinase Science. 299: 1190-1191. PMID 12595680 DOI: 10.1126/Science.1082384  0.452
2003 Goto H, Yasui Y, Kawajiri A, Nigg EA, Terada Y, Tatsuka M, Nagata Ki, Inagaki M. Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process Journal of Biological Chemistry. 278: 8526-8530. PMID 12458200 DOI: 10.1074/Jbc.M210892200  0.511
2003 Nigg EA. Chromosoma – Exploring new horizons Chromosoma. 112: 57-57. DOI: 10.1007/S00412-003-0250-8  0.337
2002 Wind M, Kelm O, Nigg EA, Lehmann WD. Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry Proteomics. 2: 1516-1523. PMID 12442251 DOI: 10.1002/1615-9861(200211)2:11<1516::Aid-Prot1516>3.0.Co;2-Y  0.424
2002 Nigg EA. Centrosome aberrations: cause or consequence of cancer progression? Nature Reviews Cancer. 2: 815-825. PMID 12415252 DOI: 10.1038/Nrc924  0.369
2002 Martin-Lluesma S, Stucke VM, Nigg EA. Role of Hec1 in Spindle Checkpoint Signaling and Kinetochore Recruitment of Mad1/Mad2 Science. 297: 2267-2270. PMID 12351790 DOI: 10.1126/Science.1075596  0.458
2002 Gruneberg U, Glotzer M, Gartner A, Nigg EA. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. The Journal of Cell Biology. 158: 901-14. PMID 12213836 DOI: 10.1083/Jcb.200202054  0.46
2002 Kufer TA, Silljé HH, Körner R, Gruss OJ, Meraldi P, Nigg EA. Human TPX2 is required for targeting Aurora-A kinase to the spindle. The Journal of Cell Biology. 158: 617-23. PMID 12177045 DOI: 10.1083/Jcb.200204155  0.553
2002 Meraldi P, Nigg EA. The centrosome cycle. Febs Letters. 521: 9-13. PMID 12067716 DOI: 10.1016/S0014-5793(02)02865-X  0.464
2002 Kelm O, Wind M, Lehmann WD, Nigg EA. Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1 Journal of Biological Chemistry. 277: 25247-25256. PMID 11994303 DOI: 10.1074/Jbc.M202855200  0.494
2002 Sumara I, Vorlaufer E, Stukenberg PT, Kelm O, Redemann N, Nigg EA, Peters JM. The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Molecular Cell. 9: 515-25. PMID 11931760 DOI: 10.1016/S1097-2765(02)00473-2  0.46
2002 Stucke VM, Silljé HHW, Arnaud L, Nigg EA. Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication The Embo Journal. 21: 1723-1732. PMID 11927556 DOI: 10.1093/Emboj/21.7.1723  0.533
2002 Mello JA, Silljé HHW, Roche DMJ, Kirschner DB, Nigg EA, Almouzni G. Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway Embo Reports. 3: 329-334. PMID 11897662 DOI: 10.1093/Embo-Reports/Kvf068  0.32
2002 Goto H, Yasui Y, Nigg EA, Inagaki M. Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes to Cells. 7: 11-17. PMID 11856369 DOI: 10.1046/J.1356-9597.2001.00498.X  0.459
2002 Meraldi P, Honda R, Nigg EA. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. The Embo Journal. 21: 483-92. PMID 11847097 DOI: 10.1093/Emboj/21.4.483  0.462
2001 Duncan PI, Pollet N, Niehrs C, Nigg EA. Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis. Experimental Cell Research. 270: 78-87. PMID 11597129 DOI: 10.1006/Excr.2001.5333  0.429
2001 Silljé HHW, Nigg EA. Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases Current Biology. 11: 1068-1073. PMID 11470414 DOI: 10.1016/S0960-9822(01)00298-6  0.489
2001 Nigg EA. Mitotic kinases as regulators of cell division and its checkpoints Nature Reviews Molecular Cell Biology. 2: 21-32. PMID 11413462 DOI: 10.1038/35048096  0.512
2001 Nigg EA. Cell cycle regulation by protein kinases and phosphatases. Ernst Schering Research Foundation Workshop. 19-46. PMID 11394046 DOI: 10.1007/978-3-662-04645-6_2  0.429
2001 Araújo SJ, Nigg EA, Wood RD. Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome Molecular and Cellular Biology. 21: 2281-2291. PMID 11259578 DOI: 10.1128/Mcb.21.7.2281-2291.2001  0.38
2001 Smits VA, Klompmaker R, Arnaud L, Rijksen G, Nigg EA, Medema RH. Polo-like kinase-1 is a target of the DNA damage checkpoint. Nature Cell Biology. 2: 672-6. PMID 10980711 DOI: 10.1038/35023629  0.398
2000 Mayor T, Stierhof Y, Tanaka K, Fry AM, Nigg EA. The Centrosomal Protein C-Nap1 Is Required for Cell Cycle–Regulated Centrosome Cohesion Journal of Cell Biology. 151: 837-846. PMID 11076968 DOI: 10.1083/Jcb.151.4.837  0.422
2000 Pahlavan G, Polanski Z, Kalab P, Golsteyn R, Nigg EA, Maro B. Characterization of Polo-like Kinase 1 during Meiotic Maturation of the Mouse Oocyte Developmental Biology. 220: 392-400. PMID 10753525 DOI: 10.1006/Dbio.2000.9656  0.504
1999 Fry AM, Mayor T, Nigg EA. Regulating centrosomes by protein phosphorylation Current Topics in Developmental Biology. 49: 291-312. PMID 11005024 DOI: 10.1016/S0070-2153(99)49014-3  0.568
1999 Meraldi P, Lukas J, Fry AM, Bartek J, Nigg EA. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nature Cell Biology. 1: 88-93. PMID 10559879 DOI: 10.1038/10054  0.455
1999 Silljé HHW, Takahashi K, Tanaka K, Houwe GV, Nigg EA. Mammalian homologues of the plant Tousled gene code for cell‐cycle‐regulated kinases with maximal activities linked to ongoing DNA replication The Embo Journal. 18: 5691-5702. PMID 10523312 DOI: 10.1093/Emboj/18.20.5691  0.495
1999 Mayor T, Meraldi P, Stierhof YD, Nigg EA, Fry AM. Protein kinases in control of the centrosome cycle. Febs Letters. 452: 92-5. PMID 10376685 DOI: 10.1016/S0014-5793(99)00534-7  0.469
1999 Fry AM, Arnaud L, Nigg EA. Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif. The Journal of Biological Chemistry. 274: 16304-10. PMID 10347187 DOI: 10.1074/jbc.274.23.16304  0.438
1999 Tanaka K, Nigg EA. Cloning and Characterization of the Murine Nek3 Protein Kinase, a Novel Member of the NIMA Family of Putative Cell Cycle Regulators Journal of Biological Chemistry. 274: 13491-13497. PMID 10224116 DOI: 10.1074/Jbc.274.19.13491  0.481
1998 Arnaud L, Pines J, Nigg EA. GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma. 107: 424-429. PMID 9914374 DOI: 10.1007/S004120050326  0.512
1998 Nigg EA. Polo-like kinases: positive regulators of cell division from start to finish. Current Opinion in Cell Biology. 10: 776-783. PMID 9914175 DOI: 10.1016/S0955-0674(98)80121-X  0.543
1998 Fry AM, Mayor T, Meraldi P, Stierhof Y, Tanaka K, Nigg EA. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. Journal of Cell Biology. 141: 1563-1574. PMID 9647649 DOI: 10.1083/Jcb.141.7.1563  0.5
1998 Blangy A, Chaussepied P, Nigg EA. Rigor-type mutation in the kinesin-related protein HsEg5 changes its subcellular localization and induces microtubule bundling. Cytoskeleton. 40: 174-182. PMID 9634214 DOI: 10.1002/(Sici)1097-0169(1998)40:2<174::Aid-Cm6>3.0.Co;2-F  0.421
1998 Descombes P, Nigg EA. The polo‐like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts The Embo Journal. 17: 1328-1335. PMID 9482730 DOI: 10.1093/Emboj/17.5.1328  0.419
1998 Fry AM, Meraldi P, Nigg EA. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. The Embo Journal. 17: 470-481. PMID 9430639 DOI: 10.1093/Emboj/17.2.470  0.542
1997 Tanaka K, Parvinen M, Nigg EA. The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis Experimental Cell Research. 237: 264-274. PMID 9434622 DOI: 10.1006/Excr.1997.3788  0.466
1997 Mundt KE, Golsteyn RM, Lane HA, Nigg EA. On the regulation and function of human polo-like kinase 1 (PLK1): Effects of overexpression on cell cycle progression Biochemical and Biophysical Research Communications. 239: 377-385. PMID 9344838 DOI: 10.1006/Bbrc.1997.7378  0.555
1997 Fry AM, Nigg EA. Characterization of mammalian NIMA-related kinases Methods in Enzymology. 283: 270-282. PMID 9251026 DOI: 10.1016/S0076-6879(97)83022-4  0.509
1997 Blangy A, Arnaud LJ, Nigg EA. Phosphorylation by p34cdc2 Protein Kinase Regulates Binding of the Kinesin-related Motor HsEg5 to the Dynactin Subunit p150Glued Journal of Biological Chemistry. 272: 19418-19424. PMID 9235942 DOI: 10.1074/Jbc.272.31.19418  0.489
1997 Nigg EA. Nucleocytoplasmic transport: signals, mechanisms and regulation Nature. 386: 779-787. PMID 9126736 DOI: 10.1038/386779A0  0.333
1997 Lane HA, Nigg EA. Cell-cycle control: POLO-like kinases join the outer circle Trends in Cell Biology. 7: 63-68. DOI: 10.1016/S0962-8924(96)10051-9  0.535
1996 Golsteyn RM, Lane HA, Mundt KE, Arnaud L, Nigg EA. The family of polo-like kinases Progress in Cell Cycle Research. 2: 107-114. PMID 9552388 DOI: 10.1007/978-1-4615-5873-6_11  0.508
1996 Lane HA, Nigg EA. Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes Journal of Cell Biology. 135: 1701-1713. PMID 8991084 DOI: 10.1083/Jcb.135.6.1701  0.5
1996 Nigg EA, Blangy A, Lane HA. Dynamic changes in nuclear architecture during mitosis: On the role of protein phosphorylation in spindle assembly and chromosome segregation Experimental Cell Research. 229: 174-180. PMID 8986594 DOI: 10.1006/Excr.1996.0356  0.57
1996 Gold MO, Tassan JP, Nigg EA, Rice AP, Herrmann CH. Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic Acids Research. 24: 3771-7. PMID 8871557 DOI: 10.1093/Nar/24.19.3771  0.495
1996 Nigg EA. Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control? Current Opinion in Cell Biology. 8: 312-317. PMID 8743880 DOI: 10.1016/S0955-0674(96)80003-2  0.468
1996 Leclerc V, Tassan JP, O'Farrell PH, Nigg EA, Léopold P. Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Molecular Biology of the Cell. 7: 505-13. PMID 8730095 DOI: 10.1091/Mbc.7.4.505  0.488
1996 Adamczewski JP, Rossignol M, Tassan JP, Nigg EA, Moncollin V, Egly JM. MAT1, cdk7 and cyclin H form a kinase complex which is UV light‐sensitive upon association with TFIIH. The Embo Journal. 15: 1877-1884. DOI: 10.1002/J.1460-2075.1996.Tb00538.X  0.44
1995 Zucca E, Nigg EA. Cell cycle regulation and the function of cancer genes Annals of Oncology. 6: 975-978. PMID 8750147 DOI: 10.1093/Oxfordjournals.Annonc.A059092  0.329
1995 Gallant P, Fry AM, Nigg EA. Protein kinases in the control of mitosis: focus on nucleocytoplasmic trafficking. Journal of Cell Science. Supplement. 19: 21-8. PMID 8655643 DOI: 10.1242/Jcs.1995.Supplement_19.3  0.572
1995 Blangy A, Lane HA, D'Hérin P, Harper M, Kress M, Nigg EA. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo Cell. 83: 1159-1169. PMID 8548803 DOI: 10.1016/0092-8674(95)90142-6  0.516
1995 Fry AM, Nigg EA. Cell Cycle: The NIMA kinase joins forces with Cdc2 Current Biology. 5: 1122-1125. PMID 8548283 DOI: 10.1016/S0960-9822(95)00227-2  0.499
1995 Golsteyn RM, Mundt KE, Fry AM, Nigg EA. Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. Journal of Cell Biology. 129: 1617-1628. PMID 7790358 DOI: 10.1083/Jcb.129.6.1617  0.581
1995 Fry AM, Schultz SJ, Bartek J, Nigg EA. Substrate Specificity and Cell Cycle Regulation of the Nek2 Protein Kinase, a Potential Human Homolog of the Mitotic Regulator NIMA of Aspergillus nidulans Journal of Biological Chemistry. 270: 12899-12905. PMID 7759549 DOI: 10.1074/Jbc.270.21.12899  0.519
1995 Nigg EA. Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays. 17: 471-480. PMID 7575488 DOI: 10.1002/Bies.950170603  0.532
1995 Tassan J, Jaquenoud M, Leopold P, Schultz SJ, Nigg EA. Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C Proceedings of the National Academy of Sciences of the United States of America. 92: 8871-8875. PMID 7568034 DOI: 10.1073/Pnas.92.19.8871  0.477
1995 Ossipow V, Tassan JP, Nigg EA, Schibler U. A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell. 83: 137-46. PMID 7553866 DOI: 10.1016/0092-8674(95)90242-2  0.333
1995 Peter M, Nigg EA. Control of Nuclear Lamina Assembly/Disassembly by Phosphorylation Advances in Molecular and Cell Biology. 13: 165-179. DOI: 10.1016/S1569-2558(08)60011-9  0.667
1995 Tassan JP, Jaquenoud M, Fry AM, Frutiger S, Hughes GJ, Nigg EA. In Vitro Assembly Of A Functional Human Cdk7-Cyclin H Complex Requires Mat1, A Novel 36 Kda Ring Finger Protein The Embo Journal. 14: 5608-5617. DOI: 10.1002/J.1460-2075.1995.Tb00248.X  0.448
1995 Devault A, Martinez AM, Fesquet D, Labbé JC, Morin N, Tassan JP, Nigg EA, Cavadore JC, Dorée M. MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. The Embo Journal. 14: 5027-5036. DOI: 10.1002/J.1460-2075.1995.Tb00185.X  0.453
1994 Mäkelä TP, Tassan JP, Nigg EA, Frutiger S, Hughes GJ, Weinberg RA. A cyclin associated with the CDK-activating kinase MO15. Nature. 371: 254-7. PMID 8078587 DOI: 10.1038/371254A0  0.509
1994 Roy R, Adamczewski JP, Seroz T, Vermeulen W, Tassan J, Schaeffer L, Nigg EA, Hoeijmakers JHJ, Egly J. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor Cell. 79: 1093-1101. PMID 8001135 DOI: 10.1016/0092-8674(94)90039-6  0.493
1994 Tassan JP, Schultz SJ, Bartek J, Nigg EA. Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase) Journal of Cell Biology. 127: 467-478. PMID 7929589 DOI: 10.1083/Jcb.127.2.467  0.541
1994 Gallant P, Nigg EA. Identification of a novel vertebrate cyclin : cyclin B3 shares properties with both A- and B-type cyclins The Embo Journal. 13: 595-605. DOI: 10.1002/J.1460-2075.1994.Tb06297.X  0.435
1993 Nigg EA. Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases Trends in Cell Biology. 3: 296-301. PMID 14731846 DOI: 10.1016/0962-8924(93)90011-O  0.486
1993 Nigg EA. Targets of cyclin-dependent protein kinases. Current Opinion in Cell Biology. 5: 187-193. PMID 8507490 DOI: 10.1016/0955-0674(93)90101-U  0.531
1993 Hennekes H, Peter M, Weber K, Nigg EA. Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2. Journal of Cell Biology. 120: 1293-1304. PMID 8449977 DOI: 10.1083/Jcb.120.6.1293  0.695
1993 Schmidt-Zachmann MS, Dargemont C, Kühn LC, Nigg EA. Nuclear export of proteins : the role of nuclear retention Cell. 74: 493-504. PMID 8348616 DOI: 10.1016/0092-8674(93)80051-F  0.404
1992 Krek W, Maridor G, Nigg EA. Casein kinase II is a predominantly nuclear enzyme. Journal of Cell Biology. 116: 43-55. PMID 1730748 DOI: 10.1083/Jcb.116.1.43  0.393
1992 Heitlinger E, Peter M, Lustig A, Villiger W, Nigg EA, Aebi U. The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins. Journal of Structural Biology. 108: 74-89. PMID 1562436 DOI: 10.1016/1047-8477(92)90009-Y  0.339
1992 Nigg EA. Assembly-disassembly of the nuclear lamina. Current Opinion in Cell Biology. 4: 105-109. PMID 1558747 DOI: 10.1016/0955-0674(92)90066-L  0.358
1992 Peter M, Sanghera JS, Pelech SL, Nigg EA. Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34(cdc2) European Journal of Biochemistry. 205: 287-294. PMID 1555589 DOI: 10.1111/J.1432-1033.1992.Tb16779.X  0.662
1992 Gallant P, Nigg EA. Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. The Journal of Cell Biology. 117: 213-24. PMID 1532584 DOI: 10.1083/Jcb.117.1.213  0.484
1992 Nigg EA, Gallant P, Krek W. Regulation of p34cdc2 protein kinase activity by phosphorylation and cyclin binding. Ciba Foundation Symposium. 170: 72-84; discussion 84. PMID 1483352 DOI: 10.1002/9780470514320.CH6  0.466
1992 Nigg EA. Assembly and cell cycle dynamics of the nuclear lamina Seminars in Cell Biology. 3: 245-253. PMID 1421170 DOI: 10.1016/1043-4682(92)90026-R  0.456
1992 Nigg EA, Kitten GT, Vorburger K. Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. Biochemical Society Transactions. 20: 500-504. PMID 1397650 DOI: 10.1042/Bst0200500  0.383
1992 Sanghera JS, Peter M, Nigg EA, Pelech SL. Immunological characterization of avian MAP kinases: Evidence for nuclear localization Molecular Biology of the Cell. 3: 775-787. PMID 1325221 DOI: 10.1091/Mbc.3.7.775  0.465
1992 Nigg EA. Signal Transduction to the Cell Nucleus Advances in Molecular and Cell Biology. 4: 103-131. DOI: 10.1016/S1569-2558(08)60175-7  0.377
1991 Heitlinger E, Peter M, Häner M, Lustig A, Aebi U, Nigg EA. Expression of chicken lamin B2 in Escherichia coli: characterization of its structure, assembly, and molecular interactions. The Journal of Cell Biology. 113: 485-95. PMID 2016332 DOI: 10.1083/Jcb.113.3.485  0.453
1991 Kitten GT, Nigg EA. The CaaX motif is required for isoprenylation, carboxyl methylation, and nuclear membrane association of lamin B2. Journal of Cell Biology. 113: 13-23. PMID 2007618 DOI: 10.1083/Jcb.113.1.13  0.35
1991 Enoch T, Peter M, Nurse P, Nigg EA. p34cdc2 acts as a lamin kinase in fission yeast. The Journal of Cell Biology. 112: 797-807. PMID 1999458 DOI: 10.1083/Jcb.112.5.797  0.553
1991 Pearson D, Nigg EA, Nagamine Y, Jans DA, Hemmings BA. Mechanisms of cAMP-mediated gene induction: Examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase Experimental Cell Research. 192: 315-318. PMID 1898592 DOI: 10.1016/0014-4827(91)90193-X  0.425
1991 Nigg EA, Krek W, Peter M. Vertebrate cdc2 kinase : its regulation by phosphorylation and its mitotic targets Cold Spring Harbor Symposia On Quantitative Biology. 56: 539-547. PMID 1819505 DOI: 10.1101/Sqb.1991.056.01.061  0.467
1991 Nigg EA, Baeuerle PA, Lührmann R. Nuclear import-export : in search of signals and mechanisms Cell. 66: 15-22. PMID 1712670 DOI: 10.1016/0092-8674(91)90135-L  0.311
1991 Bailer SM, Eppenberger HM, Griffiths G, Nigg EA. Characterization of A 54-kD protein of the inner nuclear membrane: evidence for cell cycle-dependent interaction with the nuclear lamina. Journal of Cell Biology. 114: 389-400. PMID 1650369 DOI: 10.1083/Jcb.114.3.389  0.454
1991 Krek W, Nigg EA. Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites. The Embo Journal. 10: 305-316. DOI: 10.1002/J.1460-2075.1991.Tb07951.X  0.495
1991 Peter M, Heitlinger E, Häner M, Aebi U, Nigg E. Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase. The Embo Journal. 10: 1535-1544. DOI: 10.1002/J.1460-2075.1991.Tb07673.X  0.656
1991 Krek W, Nigg EA. Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. The Embo Journal. 10: 3331-3341. DOI: 10.1002/J.1460-2075.1991.Tb04897.X  0.485
1990 Peter M, Nakagawa J, Dorée M, Labbé JC, Nigg EA. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell. 61: 591-602. PMID 2188731 DOI: 10.1016/0092-8674(90)90471-P  0.502
1990 Peter M, Nakagawa J, Dorée M, Labbé JC, Nigg EA. Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Cell. 60: 791-801. PMID 2178776 DOI: 10.1016/0092-8674(90)90093-T  0.685
1990 Nigg EA. Mechanisms of signal transduction to the cell nucleus. Advances in Cancer Research. 55: 271-310. PMID 2166999 DOI: 10.1016/S0065-230X(08)60471-6  0.421
1990 Maridor G, Krek W, Nigg EA. Structure and developmental expression of chicken nucleolin and NO38: coordinate expression of two abundant non-ribosomal nucleolar proteins. Biochimica Et Biophysica Acta. 1049: 126-133. PMID 2114180 DOI: 10.1016/0167-4781(90)90032-W  0.346
1990 NIGG E, PETER M, NAKAGAWA J, KITTEN G, DOREE M, LABBE J. Mitotic phosphorylation and disassembly of the nuclear lamina by cdc2 kinase Cell Biology International Reports. 14: 9. DOI: 10.1016/0309-1651(90)90144-N  0.482
1989 Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 56: 379-90. PMID 2914325 DOI: 10.1016/0092-8674(89)90241-9  0.39
1989 Peter M, Kitten GT, Lehner CF, Vorburger K, Bailer SM, Maridor G, Nigg EA. Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. Journal of Molecular Biology. 208: 393-404. PMID 2795656 DOI: 10.1016/0022-2836(89)90504-4  0.554
1989 Vorburger K, Kitten GT, Nigg EA. Modification of nuclear lamin proteins by a mevalonic acid derivative occurs in reticulocyte lysates and requires the cysteine residue of the C-terminal CXXM motif The Embo Journal. 8: 4007-4013. DOI: 10.1002/J.1460-2075.1989.Tb08583.X  0.352
1989 Krek W, Nigg EA. Structure and developmental expression of the chicken CDC2 kinase. The Embo Journal. 8: 3071-3078. DOI: 10.1002/J.1460-2075.1989.Tb08458.X  0.432
1988 Stick R, Angres B, Lehner CF, Nigg EA. The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum. The Journal of Cell Biology. 107: 397-406. PMID 3417755 DOI: 10.1083/Jcb.107.2.397  0.346
1988 Nigg EA. Nuclear Function and Organization: The Potential of Immunochemical Approaches International Review of Cytology-a Survey of Cell Biology. 110: 27-92. PMID 3053500 DOI: 10.1016/S0074-7696(08)61847-1  0.352
1987 Lehner CF, Stick R, Eppenberger HM, Nigg EA. Differential expression of nuclear lamin proteins during chicken development. The Journal of Cell Biology. 105: 577-87. PMID 3301871 DOI: 10.1083/Jcb.105.1.577  0.339
1986 Lehner CF, Fürstenberger G, Eppenberger HM, Nigg EA. Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors. Proceedings of the National Academy of Sciences of the United States of America. 83: 2096-9. PMID 3515346 DOI: 10.1073/Pnas.83.7.2096  0.376
1986 Nigg EA, Sefton BM, Singer SJ, Vogt PK. Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies. Virology. 151: 50-65. PMID 3083582 DOI: 10.1016/0042-6822(86)90103-0  0.375
1985 Nigg EA, Schäfer G, Hilz H, Eppenberger HM. Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes. Cell. 41: 1039-51. PMID 2988780 DOI: 10.1016/S0092-8674(85)80084-2  0.39
1985 Nigg EA, Hilz H, Eppenberger HM, Dutly F. Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus. The Embo Journal. 4: 2801-2806. DOI: 10.1002/J.1460-2075.1985.Tb04006.X  0.413
1984 Papkoff J, Nigg EA, Hunter T. The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein. Cell. 33: 161-72. PMID 6380747 DOI: 10.1016/0092-8674(83)90345-8  0.344
1983 Nigg EA, Cooper JA, Hunter T. Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane. The Journal of Cell Biology. 96: 1601-9. PMID 6304112 DOI: 10.1083/Jcb.96.6.1601  0.376
1982 Sefton BM, Hunter T, Nigg EA, Singer SJ, Walter G. Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity. Cold Spring Harbor Symposia On Quantitative Biology. 46: 939-51. PMID 6809406 DOI: 10.1101/Sqb.1982.046.01.088  0.416
1982 Nigg EA, Sefton BM, Hunter T, Walter G, Singer SJ. Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proceedings of the National Academy of Sciences of the United States of America. 79: 5322-6. PMID 6291037 DOI: 10.1073/Pnas.79.17.5322  0.336
1982 Nigg EA, Walter G, Singer SJ. On the nature of crossreactions observed with antibodies directed to defined epitopes Proceedings of the National Academy of Sciences of the United States of America. 79: 5939-5943. PMID 6193510 DOI: 10.1073/Pnas.79.19.5939  0.312
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