Lei Liang - Publications

Affiliations: 
Peking University Health Science Center, China 

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang C, Xi D, Wang H, Niu Y, Liang L, Xu F, Peng Y, Xu P. Hybrids of MEK inhibitor and NO donor as multitarget antitumor drugs. European Journal of Medicinal Chemistry. 196: 112271. PMID 32305784 DOI: 10.1016/J.Ejmech.2020.112271  0.303
2019 Li H, Xi D, Niu Y, Wang C, Xu F, Liang L, Xu P. Design, synthesis and biological evaluation of cobalt(II)-Schiff base complexes as ATP-noncompetitive MEK1 inhibitors. Journal of Inorganic Biochemistry. 195: 174-181. PMID 30954694 DOI: 10.1016/J.Jinorgbio.2019.03.022  0.311
2017 Yan G, Hao L, Niu Y, Huang W, Wang W, Xu F, Liang L, Wang C, Jin H, Xu P. 2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies. European Journal of Medicinal Chemistry. 137: 462-475. PMID 28624701 DOI: 10.1016/J.Ejmech.2017.06.020  0.34
2016 Zhou T, Cai Y, Liang L, Yang L, Xu F, Niu Y, Wang C, Zhang JL, Xu P. Discovery of a potent and highly specific β2 proteasome inhibitor from a library of copper complexes. Bioorganic & Medicinal Chemistry Letters. PMID 27816516 DOI: 10.1016/J.Bmcl.2016.10.043  0.545
2016 Yang L, Zhu Y, Shui M, Zhou T, Cai Y, Wang W, Xu F, Niu Y, Wang C, Zhang JL, Xu P, Yuan L, Liang L. Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27440529 DOI: 10.1002/Chem.201601499  0.545
2016 Yang L, Wang W, Sun Q, Xu F, Niu Y, Wang C, Liang L, Xu P. Development of novel proteasome inhibitors based on phthalazinone scaffold. Bioorganic & Medicinal Chemistry Letters. PMID 27158142 DOI: 10.1016/J.Bmcl.2016.04.067  0.314
2015 Sun Q, Xu B, Niu Y, Xu F, Liang L, Wang C, Yu J, Yan G, Wang W, Jin H, Xu P. Synthesis, bioactivity, docking and molecular dynamics studies of furan-based peptides as 20S proteasome inhibitors. Chemmedchem. 10: 498-510. PMID 25641789 DOI: 10.1002/Cmdc.201402484  0.32
2014 Liu P, Niu Y, Wang C, Sun Q, Zhai Y, Yu J, Sun J, Xu F, Yan G, Huang W, Liang L, Xu P. 4-Oxo-1,4-dihydro-quinoline-3-carboxamides as BACE-1 inhibitors: synthesis, biological evaluation and docking studies. European Journal of Medicinal Chemistry. 79: 413-21. PMID 24763262 DOI: 10.1016/J.Ejmech.2014.04.025  0.313
2013 Liang L, Wang W, Wu J, Xu F, Niu Y, Xu B, Xu P. Rational design, green synthesis, and initial evaluation of a series of full-color tunable fluorescent dyes enabled by the copper-catalyzed N-arylation of 6-phenyl pyridazinones and their application in cell imaging. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 13774-82. PMID 24038329 DOI: 10.1002/Chem.201302495  0.335
2013 Liang L, Wang W, Xu F, Niu Y, Sun Q, Xu P. Relay catalysis by a multifunctional Cu catalyst in a tandem dehydro-/dehalogenation sequence along with N-arylation. Organic Letters. 15: 2770-3. PMID 23672594 DOI: 10.1021/Ol401105X  0.322
2013 Cai YB, Liang L, Zhang J, Sun HL, Zhang JL. μ-Hydroxyl trinuclear copper(II) clusters: reactivity and unusual formation in the three-component synthesis of 1,2,3-triazoles in aqueous media. Dalton Transactions (Cambridge, England : 2003). 42: 5390-400. PMID 23420208 DOI: 10.1039/C3Dt32906B  0.552
2013 Wang C, Xu F, Niu Y, Wu Y, Sun J, Peng Y, Liang L, Xu P. Synthesis and Biological Evaluations of 3-Benzothiazol-2-yl Coumarin Derivatives as MEK1 Inhibitors Letters in Drug Design & Discovery. 10: 727-732. DOI: 10.2174/15701808113109990012  0.322
2013 Liang L, Yang G, Xu F, Niu Y, Sun Q, Xu P. Copper-Catalyzed Aerobic Dehydrogenation of C-C to C=C Bonds in the Synthesis of Pyridazinones European Journal of Organic Chemistry. 2013: 6130-6136. DOI: 10.1002/Ejoc.201300640  0.331
2013 Liang L, Yang G, Wang W, Xu F, Niu Y, Sun Q, Xu P. A Copper-Catalyzed Aerobic Cascade Dehydrogenative- Dehalogenative Reaction Advanced Synthesis & Catalysis. 355: 1284-1290. DOI: 10.1002/Adsc.201300026  0.335
2012 Liang L, Lv H, Yu Y, Wang P, Zhang JL. Iron(III) tetrakis(pentafluorophenyl)porpholactone catalyzes nitrogen atom transfer to C=C and C-H bonds with organic azides. Dalton Transactions (Cambridge, England : 2003). 41: 1457-60. PMID 22187065 DOI: 10.1039/C2Dt11995A  0.531
2011 Garner DK, Liang L, Barrios DA, Zhang JL, Lu Y. Covalent Anchor Positions Play an Important Role in Tuning Catalytic Properties of a Rationally Designed MnSalen-containing Metalloenzyme. Acs Catalysis. 1: 1083-1089. PMID 22013554 DOI: 10.1021/Cs200258E  0.573
2010 Liang L, Rao G, Sun H, Zhang J. Aerobic Oxidation of Primary Alcohols Catalyzed by Copper Salts and Catalytically Active μ-Hydroxyl-Bridged Trinuclear Copper Intermediate Advanced Synthesis & Catalysis. 352: 2371-2377. DOI: 10.1002/Adsc.201000456  0.556
2009 Zhang JL, Garner DK, Liang L, Barrios DA, Lu Y. Noncovalent modulation of pH-dependent reactivity of a Mn-salen cofactor in myoglobin with hydrogen peroxide. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 7481-9. PMID 19557774 DOI: 10.1002/Chem.200802449  0.546
2008 Zhang JL, Garner DK, Liang L, Chen Q, Lu Y. Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole. Chemical Communications (Cambridge, England). 1665-7. PMID 18368158 DOI: 10.1039/B718915J  0.529
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