Hiroyuki Osada - Publications

Chemical Biology Research Group RIKEN 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kwong MMY, Lee JW, Samian MR, Watanabe N, Osada H, Ong EBB. Comparison of microplate- and bottle-based methods to age yeast for chronological life span assays. Journal of Microbiological Methods. 105743. PMID 31629019 DOI: 10.1016/j.mimet.2019.105743  0.96
2019 Yamamoto K, Futamura Y, Uson-Lopez RA, Aono H, Shimizu T, Osada H. YO-001A, a new antifungal agent produced by Streptomyces sp. YO15-A001. The Journal of Antibiotics. PMID 31601980 DOI: 10.1038/s41429-019-0239-z  0.36
2019 Yoshida K, Kondoh Y, Iwahashi F, Nakano T, Honda K, Nagano E, Osada H. Abscisic Acid Derivatives with Different Alkyl Chain Lengths Activate Distinct Abscisic Acid Receptor Subfamilies. Acs Chemical Biology. PMID 31497942 DOI: 10.1021/acschembio.9b00453  0.36
2019 Nogawa T, Kawatani M, Okano A, Futamura Y, Aono H, Shimizu T, Kato N, Kikuchi H, Osada H. Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007. The Journal of Antibiotics. PMID 31481762 DOI: 10.1038/s41429-019-0229-1  0.36
2019 Lopez JAV, Nogawa T, Futamura Y, Shimizu T, Osada H. Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647. The Journal of Antibiotics. PMID 31395970 DOI: 10.1038/s41429-019-0217-5  0.36
2019 Takase S, Kurokawa R, Kondoh Y, Honda K, Suzuki T, Kawahara T, Ikeda H, Dohmae N, Osada H, Shin-Ya K, Kushiro T, Yoshida M, Matsumoto K. Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure. Acs Chemical Biology. PMID 31365229 DOI: 10.1021/acschembio.9b00410  0.36
2019 Shu K, Iwamoto N, Honda K, Kondoh Y, Hirano H, Osada H, Ohno H, Fujii N, Oishi S. Development of Mirror-Image Screening Systems for XIAP BIR3 Domain Inhibitors. Bioconjugate Chemistry. PMID 30888797 DOI: 10.1021/acs.bioconjchem.9b00154  0.36
2019 Subedi A, Muroi M, Futamura Y, Kawamura T, Aono H, Nishi M, Ryo A, Watanabe N, Osada H. A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition. Febs Letters. PMID 30874300 DOI: 10.1002/1873-3468.13361  0.96
2019 Murashima A, Shinjo K, Katsushima K, Onuki T, Kondoh Y, Osada H, Kagaya N, Shinya K, Kimura H, Yoshida M, Murakami S, Kondo Y. Identification of a Chemical Modulator of EZH2-mediated Silencing by Cell-based High-throughput Screening Assay. Journal of Biochemistry. PMID 30690451 DOI: 10.1093/jb/mvz007  0.36
2019 Suvarna K, Honda K, Muroi M, Kondoh Y, Osada H, Watanabe N. A small-molecule ligand of valosin-containing protein/p97 inhibits cancer cell-accelerated fibroblast migration. The Journal of Biological Chemistry. PMID 30610116 DOI: 10.1074/jbc.RA118.004741  0.96
2018 Son S, Hong YS, Futamura Y, Jang M, Lee JK, Heo KT, Ko SK, Lee JS, Takahashi S, Osada H, Jang JH, Ahn JS. Catenulisporolides, Glycosylated Triene Macrolides from the Chemically Underexploited Actinomycete Catenulispora Species. Organic Letters. PMID 30379079 DOI: 10.1021/acs.orglett.8b03160  0.36
2018 Otaka J, Shimizu T, Futamura Y, Hashizume D, Osada H. Correction to "Structures and Synthesis of Hitoyopodins: Bioactive Aromatic Sesquiterpenoids Produced by the Mushroom Coprinopsis cinerea". Organic Letters. PMID 30370774 DOI: 10.1021/acs.orglett.8b03400  0.36
2018 Nogawa T, Futamura Y, Okano A, Suto M, Nakamura J, Ishihara K, Osada H. Construction of a potato fraction library for the investigation of functional secondary metabolites. Bioscience, Biotechnology, and Biochemistry. 1-11. PMID 30286702 DOI: 10.1080/09168451.2018.1525273  0.36
2018 Otaka J, Shimizu T, Futamura Y, Hashizume D, Osada H. Structures and Synthesis of Hitoyopodins: Bioactive Aromatic Sesquiterpenoids Produced by the Mushroom Coprinopsis cinerea. Organic Letters. PMID 30234313 DOI: 10.1021/acs.orglett.8b02788  0.36
2018 Futamura Y, Muroi M, Aono H, Kawatani M, Hayashida M, Sekine T, Nogawa T, Osada H. Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms. Biochimica Et Biophysica Acta. PMID 29883687 DOI: 10.1016/j.bbapap.2018.06.001  0.36
2018 Robke L, Futamura Y, Konstantinidis G, Wilke J, Aono H, Mahmoud Z, Watanabe N, Wu YW, Osada H, Laraia L, Waldmann H. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chemical Science. 9: 3014-3022. PMID 29732085 DOI: 10.1039/c7sc05040b  0.96
2018 Jia ZJ, Takayama H, Futamura Y, Aono H, Bauer JO, Strohmann C, Antonchick AP, Osada H, Waldmann H. Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity. The Journal of Organic Chemistry. PMID 29460633 DOI: 10.1021/acs.joc.7b03202  0.36
2018 Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, ... ... Osada H, et al. Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide. Scientific Reports. 8: 2769. PMID 29426822 DOI: 10.1038/s41598-018-20987-w  0.36
2018 Takagi H, Nogawa T, Futamura Y, Takahashi S, Osada H. Kinanthraquinone, a new anthraquinone carboxamide isolated from Streptomyces reveromyceticus SN-593-44. The Journal of Antibiotics. PMID 29410517 DOI: 10.1038/s41429-017-0020-0  0.36
2018 Suvarna K, Honda K, Kondoh Y, Osada H, Watanabe N. Identification of a small-molecule ligand of β-arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells. Cancer Medicine. PMID 29380537 DOI: 10.1002/cam4.1339  0.96
2017 Wilke J, Kawamura T, Watanabe N, Osada H, Ziegler S, Waldmann H. Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion. Bioorganic & Medicinal Chemistry. PMID 29170028 DOI: 10.1016/j.bmc.2017.11.009  0.96
2017 Nogawa T, Kato N, Shimizu T, Okano A, Futamura Y, Takahashi S, Osada H. Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058. The Journal of Antibiotics. PMID 28901329 DOI: 10.1038/ja.2017.103  0.36
2017 Otaka J, Hashizume D, Masumoto Y, Muranaka A, Uchiyama M, Koshino H, Futamura Y, Osada H. Hitoyol A and B, Two Norsesquiterpenoids from the Basidiomycete Coprinopsis cinerea. Organic Letters. 19: 4030-4033. PMID 28726419 DOI: 10.1021/acs.orglett.7b01784  0.36
2017 Waldmann H, Robke L, Laraia L, Carnero Corrales MA, Konstantinidis G, Muroi M, Richters A, Winzker M, Engbring T, Tomassi S, Watanabe N, Osada H, Rauh D, Wu Y, Engel J. Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34. Angewandte Chemie (International Ed. in English). PMID 28544137 DOI: 10.1002/anie.201703738  0.96
2017 Maeda K, Nakajima Y, Motoyama T, Kondoh Y, Kawamura T, Kanamaru K, Ohsato S, Nishiuchi T, Yoshida M, Osada H, Kobayashi T, Kimura M. Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein. Pesticide Biochemistry and Physiology. 138: 1-7. PMID 28456298 DOI: 10.1016/j.pestbp.2017.03.006  0.36
2017 Ishiba H, Noguchi T, Shu K, Ohno H, Honda K, Kondoh Y, Osada H, Fujii N, Oishi S. Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction. Bioorganic & Medicinal Chemistry Letters. PMID 28400230 DOI: 10.1016/j.bmcl.2017.03.082  0.36
2017 Chutiwitoonchai N, Mano T, Kakisaka M, Sato H, Kondoh Y, Osada H, Kotani O, Yokoyama M, Sato H, Aida Y. Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development. Virology. 507: 32-39. PMID 28399435 DOI: 10.1016/j.virol.2017.04.001  0.36
2017 Shikata Y, Kiga M, Futamura Y, Aono H, Inoue H, Kawada M, Osada H, Imoto M. Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells. Cancer Science. PMID 28107588 DOI: 10.1111/cas.13172  0.36
2017 Nogawa T, Ogita N, Futamura Y, Negishi S, Watanabe N, Osada H. Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684. The Journal of Antibiotics. PMID 28096547 DOI: 10.1038/ja.2016.167  0.96
2017 Jang JP, Nogawa T, Futamura Y, Shimizu T, Hashizume D, Takahashi S, Jang JH, Ahn JS, Osada H. Octaminomycins A and B, Cyclic Octadepsipeptides Active against Plasmodium falciparum. Journal of Natural Products. PMID 28055207 DOI: 10.1021/acs.jnatprod.6b00758  0.36
2017 Noguchi T, Ishiba H, Honda K, Kondoh Y, Osada H, Ohno H, Fujii N, Oishi S. Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems. Bioconjugate Chemistry. 28: 609-619. PMID 28032751 DOI: 10.1021/acs.bioconjchem.6b00692  0.36
2017 Futamura Y, Yamamoto K, Osada H. Phenotypic screening meets natural products in drug discovery. Bioscience, Biotechnology, and Biochemistry. 81: 28-31. PMID 27885937 DOI: 10.1080/09168451.2016.1248365  0.36
2016 Hasebe F, Matsuda K, Shiraishi T, Futamura Y, Nakano T, Tomita T, Ishigami K, Taka H, Mineki R, Fujimura T, Osada H, Kuzuyama T, Nishiyama M. Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces. Nature Chemical Biology. 12: 967-972. PMID 28288097 DOI: 10.1038/nchembio.2181  0.36
2016 Ong WD, Okubo-Kurihara E, Kurihara Y, Shimada S, Makita Y, Kawashima M, Honda K, Kondoh Y, Watanabe N, Osada H, Cutler SR, Sudesh K, Matsui M. Chemical-Induced Inhibition of Blue Light-Mediated Seedling Development Caused by Disruption of Upstream Signal Transduction Involving Cryptochromes in Arabidopsis thaliana. Plant & Cell Physiology. PMID 28011868 DOI: 10.1093/pcp/pcw181  0.96
2016 Kawatani M, Muroi M, Wada A, Inoue G, Futamura Y, Aono H, Shimizu K, Shimizu T, Igarashi Y, Takahashi-Ando N, Osada H. Proteomic profiling reveals that collismycin A is an iron chelator. Scientific Reports. 6: 38385. PMID 27922079 DOI: 10.1038/srep38385  0.36
2016 Otaka J, Komatsu M, Miyazaki Y, Futamura Y, Osada H. Two new triterpenoids from the roots of Pinus densiflora. Bioscience, Biotechnology, and Biochemistry. 1-4. PMID 27908219 DOI: 10.1080/09168451.2016.1263149  0.36
2016 Kunii M, Ohara-Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, Shimizu T, Simizu S, Lin B, Nunomura K, Aoyagi K, Ohno M, Ohmuraya M, Sato T, Yoshimura SI, ... ... Osada H, et al. Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells. The Journal of Cell Biology. PMID 27697926 DOI: 10.1083/jcb.201604030  0.36
2016 Nogawa T, Okano A, Lim CL, Futamura Y, Shimizu T, Takahashi S, Ibrahim D, Osada H. Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355. The Journal of Antibiotics. PMID 27599762 DOI: 10.1038/ja.2016.113  0.36
2016 Uesugi S, Muroi M, Kondoh Y, Shiono Y, Osada H, Kimura KI. Allantopyrone A activates Keap1-Nrf2 pathway and protects PC12 cells from oxidative stress-induced cell death. The Journal of Antibiotics. PMID 27507633 DOI: 10.1038/ja.2016.99  0.36
2016 Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H. Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ. Scientific Reports. 6: 29881. PMID 27431267 DOI: 10.1038/srep29881  0.96
2016 Subedi A, Futamura Y, Nishi M, Ryo A, Watanabe N, Osada H. High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: Involvement of mitochondrial metabolism. Biochemical and Biophysical Research Communications. PMID 27363336 DOI: 10.1016/j.bbrc.2016.06.128  0.96
2016 Jang JP, Takahashi S, Futamura Y, Nogawa T, Jang JH, Ahn JS, Osada H. RK-144171, a new benadrostin derivative produced by Streptomyces sp. RK88-1441. The Journal of Antibiotics. PMID 27270302 DOI: 10.1038/ja.2016.65  0.36
2016 Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanaka M, Honda K, Osada H. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival. Scientific Reports. 6: 26521. PMID 27210421 DOI: 10.1038/srep26521  0.36
2016 Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Ohno H, Osada H, Fujii N. Screening of a virtual mirror-image library of natural products. Chemical Communications (Cambridge, England). PMID 27198617 DOI: 10.1039/c6cc03114e  0.36
2016 Subedi A, Shimizu T, Ryo A, Sanada E, Watanabe N, Osada H. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochemical and Biophysical Research Communications. PMID 27120460 DOI: 10.1016/j.bbrc.2016.04.124  0.96
2016 Ursu A, Illich DJ, Takemoto Y, Porfetye AT, Zhang M, Brockmeyer A, Janning P, Watanabe N, Osada H, Vetter IR, Ziegler S, Schöler HR, Waldmann H. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chemical Biology. PMID 27049670 DOI: 10.1016/j.chembiol.2016.02.015  0.96
2016 Son S, Ko SK, Jang M, Kim JW, Kim GS, Lee JK, Jeon ES, Futamura Y, Ryoo IJ, Lee JS, Oh H, Hong YS, Kim BY, Takahashi S, Osada H, et al. New Cyclic Lipopeptides of the Iturin Class Produced by Saltern-Derived Bacillus sp. KCB14S006. Marine Drugs. 14. PMID 27049393 DOI: 10.3390/md14040072  0.96
2016 Watanabe N, Osada H. Small molecules that target phosphorylation dependent protein-protein interaction. Bioorganic & Medicinal Chemistry. PMID 27017542 DOI: 10.1016/j.bmc.2016.03.023  0.96
2016 Muroi M, Futamura Y, Osada H. Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase. Natural Product Reports. 33: 621-5. PMID 26996806 DOI: 10.1039/c5np00106d  0.36
2016 Sun X, Hirai G, Ueki M, Hirota H, Wang Q, Hongo Y, Nakamura T, Hitora Y, Takahashi H, Sodeoka M, Osada H, Hamamoto M, Yoshida M, Yashiroda Y. Identification of novel secreted fatty acids that regulate nitrogen catabolite repression in fission yeast. Scientific Reports. 6: 20856. PMID 26892493 DOI: 10.1038/srep20856  0.96
2016 Hashimoto M, Bhuyan F, Hiyoshi M, Noyori O, Nasser H, Miyazaki M, Saito T, Kondoh Y, Osada H, Kimura S, Hase K, Ohno H, Suzu S. Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 196: 1832-41. PMID 26773158 DOI: 10.4049/jimmunol.1500845  0.36
2016 Shinohara Y, Kawatani M, Futamura Y, Osada H, Koyama Y. An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae. The Journal of Antibiotics. 69: 4-8. PMID 26126743 DOI: 10.1038/ja.2015.73  0.36
2015 Son S, Ko SK, Kim JW, Lee JK, Jang M, Ryoo IJ, Hwang GJ, Kwon MC, Shin KS, Futamura Y, Hong YS, Oh H, Kim BY, Ueki M, Takahashi S, ... Osada H, et al. Structures and biological activities of azaphilones produced by Penicillium sp. KCB11A109 from a ginseng field. Phytochemistry. PMID 26712614 DOI: 10.1016/j.phytochem.2015.12.008  0.96
2015 Hagiwara K, Ishii H, Murakami T, Takeshima SN, Chutiwitoonchai N, Kodama EN, Kawaji K, Kondoh Y, Honda K, Osada H, Tsunetsugu-Yokota Y, Suzuki M, Aida Y. Synthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 Inhibitor. Plos One. 10: e0145573. PMID 26701275 DOI: 10.1371/journal.pone.0145573  0.36
2015 Soeda Y, Yoshikawa M, Almeida OF, Sumioka A, Maeda S, Osada H, Kondoh Y, Saito A, Miyasaka T, Kimura T, Suzuki M, Koyama H, Yoshiike Y, Sugimoto H, Ihara Y, et al. Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups. Nature Communications. 6: 10216. PMID 26671725 DOI: 10.1038/ncomms10216  0.96
2015 Lim CL, Nogawa T, Okano A, Futamura Y, Kawatani M, Takahashi S, Ibrahim D, Osada H. Unantimycin A, a new neoantimycin analog isolated from a microbial metabolite fraction library. The Journal of Antibiotics. PMID 26648115 DOI: 10.1038/ja.2015.124  0.96
2015 Mizuno M, Miyazawa K, Tabuchi M, Tanaka M, Yoshizako M, Minamoto C, Torii Y, Tamaoka Y, Kawatani M, Osada H, Maeda H, Goto S. Reveromycin A Administration Prevents Alveolar Bone Loss in Osteoprotegerin Knockout Mice with Periodontal Disease. Scientific Reports. 5: 16510. PMID 26561427 DOI: 10.1038/srep16510  0.96
2015 Yun CS, Motoyama T, Osada H. Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme. Nature Communications. 6: 8758. PMID 26503170 DOI: 10.1038/ncomms9758  0.96
2015 Ito T, Kondoh Y, Yoshida K, Umezawa T, Shimizu T, Shinozaki K, Osada H. Novel Abscisic Acid Antagonists Identified with Chemical Array Screening. Chembiochem : a European Journal of Chemical Biology. PMID 26493545 DOI: 10.1002/cbic.201500429  0.96
2015 Kim JW, Ko SK, Son S, Shin KS, Ryoo IJ, Hong YS, Oh H, Hwang BY, Hirota H, Takahashi S, Kim BY, Osada H, Jang JH, Ahn JS. Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005. Bioorganic & Medicinal Chemistry Letters. PMID 26403931 DOI: 10.1016/j.bmcl.2015.09.026  0.96
2015 Miyazawa T, Takahashi S, Kawata A, Panthee S, Hayashi T, Shimizu T, Nogawa T, Osada H. Identification of middle chain fatty acyl-CoA ligase responsible for the biosynthesis of 2-alkylmalonyl-CoAs for polyketide extender unit. The Journal of Biological Chemistry. PMID 26378232 DOI: 10.1074/jbc.M115.677195  0.96
2015 Kakeya H, Kaida D, Sekiya H, Nagai K, Yoshida M, Osada H. RQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis. The Journal of Antibiotics. PMID 26350783 DOI: 10.1038/ja.2015.94  0.96
2015 Kakisaka M, Sasaki Y, Yamada K, Kondoh Y, Hikono H, Osada H, Tomii K, Saito T, Aida Y. A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein. Plos Pathogens. 11: e1005062. PMID 26222066 DOI: 10.1371/journal.ppat.1005062  0.36
2015 Tang R, Gao L, Kawatani M, Chen J, Cao X, Osada H, Xiang L, Qi J. Neuritogenic Activity of Tetradecyl 2,3-Dihydroxybenzoate Is Mediated through the Insulin-Like Growth Factor 1 Receptor/Phosphatidylinositol 3 Kinase/Mitogen-Activated Protein Kinase Signaling Pathway. Molecular Pharmacology. 88: 326-34. PMID 26013540 DOI: 10.1124/mol.115.097758  0.96
2015 Kawatani M, Fukushima Y, Kondoh Y, Honda K, Sekine T, Yamaguchi Y, Taniguchi N, Osada H. Identification of matrix metalloproteinase inhibitors by chemical arrays. Bioscience, Biotechnology, and Biochemistry. 79: 1597-602. PMID 25988721 DOI: 10.1080/09168451.2015.1045829  0.96
2015 Minegishi H, Futamura Y, Fukashiro S, Muroi M, Kawatani M, Osada H, Nakamura H. Methyl 3-((6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)amino)benzoate (GN39482) as a tubulin polymerization inhibitor identified by morphobase and chemproteobase profiling methods Journal of Medicinal Chemistry. 58: 4230-4241. PMID 25938266 DOI: 10.1021/acs.jmedchem.5b00035  0.96
2015 Kato N, Nogawa T, Hirota H, Jang JH, Takahashi S, Ahn JS, Osada H. A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis. Biochemical and Biophysical Research Communications. 460: 210-5. PMID 25770422 DOI: 10.1016/j.bbrc.2015.03.011  0.96
2015 Kondoh Y, Honda K, Osada H. Construction and application of a photo-cross-linked chemical array. Methods in Molecular Biology (Clifton, N.J.). 1263: 29-41. PMID 25618334 DOI: 10.1007/978-1-4939-2269-7_3  0.36
2015 Yamamuro D, Uchida R, Ohtawa M, Arima S, Futamura Y, Katane M, Homma H, Nagamitsu T, Osada H, Tomoda H. Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives. Bioorganic & Medicinal Chemistry Letters. 25: 313-6. PMID 25488842 DOI: 10.1016/j.bmcl.2014.11.042  0.36
2015 Hayase H, Watanabe N, Lim CL, Nogawa T, Komatsuya K, Kita K, Osada H. Inhibition of malaria parasite growth by quinomycin A and its derivatives through DNA-intercalating activity. Bioscience, Biotechnology, and Biochemistry. 79: 633-5. PMID 25471083 DOI: 10.1080/09168451.2014.987205  0.96
2015 Jang JP, Nogawa T, Uramoto M, Okano A, Futamura Y, Shimizu T, Takahashi S, Jang JH, Ahn JS, Osada H. RK-270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270. The Journal of Antibiotics. 68: 293-5. PMID 25315758 DOI: 10.1038/ja.2014.141  0.36
2014 Choi SB, Choong YS, Saito A, Wahab HA, Najimudin N, Watanabe N, Osada H, Ong EB. In Silico Investigation of a HIV-1 Vpr Inhibitor Binding Site: Potential for Virtual Screening and anti-HIV Drug Design. Molecular Informatics. 33: 742-8. PMID 27485420 DOI: 10.1002/minf.201400080  0.96
2014 Kawamura T, Kondoh Y, Muroi M, Kawatani M, Osada H. A small molecule that induces reactive oxygen species via cellular glutathione depletion. The Biochemical Journal. 463: 53-63. PMID 25011393 DOI: 10.1042/BJ20140669  0.36
2014 Aizawa T, Kim SY, Takahashi S, Koshita M, Tani M, Futamura Y, Osada H, Funa N. Alkyldihydropyrones, new polyketides synthesized by a type III polyketide synthase from Streptomyces reveromyceticus. The Journal of Antibiotics. 67: 819-23. PMID 24984800 DOI: 10.1038/ja.2014.80  0.36
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