Xiao Le Kong, PhD - Publications

Affiliations: 
2004-2008 King's College London, London, UK 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhou T, Kong XL, Hider RC. Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands. Dalton Transactions (Cambridge, England : 2003). PMID 30793715 DOI: 10.1039/C8Dt05014G  0.67
2016 Xie YY, Lu Z, Kong XL, Zhou T, Bansal S, Hider R. Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones - Attempted optimization of the orally active iron chelator, deferiprone. European Journal of Medicinal Chemistry. 115: 132-140. PMID 27014847 DOI: 10.1016/J.Ejmech.2016.03.014  0.722
2016 Li J, Olaleye ED, Kong X, Zhou T, Ma Y, Jurach J, Al Rugaie O, Hider RC, Zhang G, Alsam S, Abbate V. Macromolecular iron-chelators via RAFT-polymerization for the inhibition of methicillin-resistant Staphylococcus aureus growth Polymer (United Kingdom). 87: 64-72. DOI: 10.1016/J.Polymer.2016.01.073  0.751
2015 Zhou YJ, Liu MS, Osamah AR, Kong XL, Alsam S, Battah S, Xie YY, Hider RC, Zhou T. Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains. European Journal of Medicinal Chemistry. 94: 8-21. PMID 25747496 DOI: 10.1016/J.Ejmech.2015.02.050  0.606
2014 Zhang MX, Zhu CF, Zhou YJ, Kong XL, Hider RC, Zhou T. Design, synthesis, and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity. Chemical Biology & Drug Design. 84: 659-68. PMID 24890019 DOI: 10.1111/Cbdd.12358  0.673
2013 Arezes J, Costa M, Vieira I, Dias V, Kong XL, Fernandes R, Vos M, Carlsson A, Rikers Y, Porto G, Rangel M, Hider RC, Pinto JP. Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species. Plos One. 8: e79870. PMID 24278199 DOI: 10.1371/Journal.Pone.0079870  0.625
2013 Li DF, Hu PP, Liu MS, Kong XL, Zhang JC, Hider RC, Zhou T. Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. Journal of Agricultural and Food Chemistry. 61: 6597-603. PMID 23802151 DOI: 10.1021/Jf401585F  0.511
2013 Zhu CF, Qiu DH, Kong XL, Hider RC, Zhou T. Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol. The Journal of Pharmacy and Pharmacology. 65: 512-20. PMID 23488779 DOI: 10.1111/Jphp.12013  0.668
2012 Chen YL, Barlow DJ, Kong XL, Ma YM, Hider RC. Prediction of 3-hydroxypyridin-4-one (HPO) log K1 values for Fe(III). Dalton Transactions (Cambridge, England : 2003). 41: 10784-91. PMID 22854534 DOI: 10.1039/C2Dt31254A  0.707
2012 Chen YL, Barlow DJ, Kong XL, Ma YM, Hider RC. Prediction of 3-hydroxypyridin-4-one (HPO) hydroxyl pKa values. Dalton Transactions (Cambridge, England : 2003). 41: 6549-57. PMID 22395734 DOI: 10.1039/C2Dt12396G  0.689
2012 Xie Y, Liu M, Hu P, Kong X, Qiu D, Xu J, Hider RC, Zhou T. Synthesis, physico-chemical properties, and antimicrobial evaluation of a new series of iron(III) hexadentate chelators Medicinal Chemistry Research. 22: 2351-2359. DOI: 10.1007/S00044-012-0229-1  0.683
2011 Xu B, Kong XL, Zhou T, Qiu DH, Chen YL, Liu MS, Yang RH, Hider RC. Synthesis, iron(III)-binding affinity and in vitro evaluation of 3-hydroxypyridin-4-one hexadentate ligands as potential antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. 21: 6376-80. PMID 21937227 DOI: 10.1016/J.Bmcl.2011.08.097  0.752
2011 Hider RC, Kong XL. Glutathione: a key component of the cytoplasmic labile iron pool. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 24: 1179-87. PMID 21769609 DOI: 10.1007/S10534-011-9476-8  0.627
2011 Staff K, Brown MB, Chilcott RP, Hider RC, Jones SA, Kong XL. Ga(III) complexes-The effect of metal coordination on potential systemic absorption after topical exposure Toxicology Letters. 202: 155-160. PMID 21315140 DOI: 10.1016/J.Toxlet.2011.01.017  0.387
2011 Gaeta A, Molina-Holgado F, Kong XL, Salvage S, Fakih S, Francis PT, Williams RJ, Hider RC. Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease. Bioorganic & Medicinal Chemistry. 19: 1285-97. PMID 21236688 DOI: 10.1016/J.Bmc.2010.12.007  0.605
2010 Piyamongkol S, Ma YM, Kong XL, Liu ZD, Aytemir MD, van der Helm D, Hider RC. Amido-3-hydroxypyridin-4-ones as iron(III) ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 6374-81. PMID 20397153 DOI: 10.1002/Chem.200902455  0.691
2009 Silva AM, Kong X, Parkin MC, Cammack R, Hider RC. Iron(III) citrate speciation in aqueous solution. Dalton Transactions (Cambridge, England : 2003). 8616-25. PMID 19809738 DOI: 10.1039/B910970F  0.63
2009 Silva AM, Kong X, Hider RC. Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 771-8. PMID 19288211 DOI: 10.1007/S10534-009-9224-5  0.475
2008 Zhou T, Kong XL, Liu ZD, Liu DY, Hider RC. Synthesis and iron(III)-chelating properties of novel 3-hydroxypyridin-4-one hexadentate ligand-containing copolymers. Biomacromolecules. 9: 1372-80. PMID 18373358 DOI: 10.1021/Bm701122U  0.758
2006 Zhou T, Neubert H, Liu DY, Liu ZD, Ma YM, Kong XL, Luo W, Mark S, Hider RC. Iron binding dendrimers: a novel approach for the treatment of haemochromatosis. Journal of Medicinal Chemistry. 49: 4171-82. PMID 16821777 DOI: 10.1021/Jm0600949  0.746
2005 Zhou T, Liu ZD, Neubert H, Kong XL, Ma YM, Hider RC. High affinity iron(III) scavenging by a novel hexadentate 3-hydroxypyridin-4-one-based dendrimer: synthesis and characterization. Bioorganic & Medicinal Chemistry Letters. 15: 5007-11. PMID 16153843 DOI: 10.1016/J.Bmcl.2005.08.008  0.731
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