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Mioara Larion, Ph.D. - Publications

Affiliations: 
Chemistry & Biochemistry Florida State University, Tallahassee, FL, United States 
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ruiz-Rodado V, Seki T, Dowdy T, Lita A, Zhang M, Han S, Yang C, Cherukuri MK, Gilbert MR, Larion M. Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma. Cancers. 12. PMID 32575619 DOI: 10.3390/Cancers12061633  0.367
2020 Yu D, Liu Y, Zhou Y, Ruiz-Rodado V, Larion M, Xu G, Yang C. Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 32312817 DOI: 10.1073/Pnas.1913633117  0.316
2020 Han S, Liu Y, Cai SJ, Qian M, Ding J, Larion M, Gilbert MR, Yang C. IDH mutation in glioma: molecular mechanisms and potential therapeutic targets. British Journal of Cancer. PMID 32291392 DOI: 10.1038/S41416-020-0814-X  0.325
2020 Ren L, Ruiz-Rodado V, Dowdy T, Huang S, Issaq SH, Beck J, Wang H, Tran Hoang C, Lita A, Larion M, LeBlanc AK. Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma. Cancer & Metabolism. 8: 4. PMID 32158544 DOI: 10.1186/S40170-020-0209-8  0.312
2019 Victor RR, Malta TM, Seki T, Lita A, Dowdy T, Celiku O, Cavazos-Saldana A, Li A, Liu Y, Han S, Zhang W, Song H, Davis D, Lee S, Trepel JB, ... ... Larion M, et al. Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas. Neuro-Oncology. PMID 31665443 DOI: 10.1093/Neuonc/Noz207  0.316
2019 Yeung C, Gibson AE, Issaq SH, Oshima N, Baumgart JT, Edessa LD, Rai G, Urban DJ, Johnson MS, Benavides GA, Squadrito GL, Yohe ME, Lei H, Eldridge S, Hamre J, ... ... Larion M, et al. Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma. Cancer Research. PMID 31431459 DOI: 10.1158/0008-5472.Can-19-0217  0.322
2019 Larion M, Hansen A, Bruschweiler-Li L, Tugarinov V, Brüschweiler R, Miller B. Specific 13CH3 Labeling and NMR Reveal the Role of Structural Dynamics to Enzymatic Function Biophysical Journal. 116: 470a. DOI: 10.1016/J.Bpj.2018.11.2540  0.443
2018 Larion M, Dowdy T, Ruiz-Rodado V, Meyer MW, Song H, Zhang W, Davis D, Gilbert MR, Lita A. Detection of Metabolic Changes Induced via Drug Treatments in Live Cancer Cells and Tissue Using Raman Imaging Microscopy. Biosensors. 9. PMID 30597885 DOI: 10.3390/Bios9010005  0.314
2017 Rodado VR, Lita A, Dowdy T, Gilbert MR, Larion M. Abstract 2508: Profiling the metabolic effects of AGI-5198 treatment on IDH1-mutated gliomas Cancer Research. 77: 2508-2508. DOI: 10.1158/1538-7445.Am2017-2508  0.336
2015 Larion M, Miller B, Brüschweiler R. Conformational heterogeneity and intrinsic disorder in enzyme regulation: Glucokinase as a case study. Intrinsically Disordered Proteins. 3: e1011008. PMID 28232887 DOI: 10.1080/21690707.2015.1011008  0.507
2015 Whittington AC, Larion M, Bowler JM, Ramsey KM, Brüschweiler R, Miller BG. Dual allosteric activation mechanisms in monomeric human glucokinase. Proceedings of the National Academy of Sciences of the United States of America. 112: 11553-8. PMID 26283387 DOI: 10.1073/Pnas.1506664112  0.587
2015 Larion M, Hansen AL, Zhang F, Bruschweiler-Li L, Tugarinov V, Miller BG, Brüschweiler R. Kinetic Cooperativity in Human Pancreatic Glucokinase Originates from Millisecond Dynamics of the Small Domain. Angewandte Chemie (International Ed. in English). 54: 8129-32. PMID 26013420 DOI: 10.1002/Anie.201501204  0.565
2014 Martinez JA, Larion M, Conejo MS, Porter CM, Miller BG. Role of connecting loop I in catalysis and allosteric regulation of human glucokinase. Protein Science : a Publication of the Protein Society. 23: 915-22. PMID 24723372 DOI: 10.1002/Pro.2473  0.56
2012 Larion M, Salinas RK, Bruschweiler-Li L, Miller BG, Brüschweiler R. Order-Disorder Transitions Govern Kinetic Cooperativity and Allostery of Monomeric Human Glucokinase Plos Biology. 10. PMID 23271955 DOI: 10.1371/Journal.Pbio.1001452  0.584
2012 Larion M, Miller BG. Homotropic allosteric regulation in monomeric mammalian glucokinase Archives of Biochemistry and Biophysics. 519: 103-111. PMID 22107947 DOI: 10.1016/J.Abb.2011.11.007  0.588
2010 Larion M, Miller BG. Global fit analysis of glucose binding curves reveals a minimal model for kinetic cooperativity in human glucokinase Biochemistry. 49: 8902-8911. PMID 20828143 DOI: 10.1021/Bi1008672  0.583
2010 Larion M, Salinas RK, Bruschweiler-Li L, Brüschweiler R, Miller BG. Direct evidence of conformational heterogeneity in human pancreatic glucokinase from high-resolution nuclear magnetic resonance Biochemistry. 49: 7969-7971. PMID 20735087 DOI: 10.1021/Bi101098F  0.56
2009 Larion M, Miller BG. 23-Residue C-terminal α-helix governs kinetic cooperativity in monomeric human glucokinase Biochemistry. 48: 6157-6165. PMID 19473033 DOI: 10.1021/Bi9007534  0.537
2007 Larion M, Moore LB, Thompson SM, Miller BG. Divergent evolution of function in the ROK sugar kinase superfamily: role of enzyme loops in substrate specificity. Biochemistry. 46: 13564-72. PMID 17979299 DOI: 10.1021/Bi700924D  0.599
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