John William Keller - Related publications

University of Alaska Fairbanks, Fairbanks, AK, United States 
Organic chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Wilkinson HC, Dalby PA. Fine-tuning the activity and stability of an evolved enzyme active-site through non-canonical amino-acids. The Febs Journal. PMID 32897608 DOI: 10.1111/febs.15560   
2020 Iacovino LG, Savino S, Borg AJE, Binda C, Nidetzky B, Mattevi A. Crystallographic snapshots of UDP-glucuronic acid 4-epimeraseligand binding, rotation and reduction. The Journal of Biological Chemistry. PMID 32661196 DOI: 10.1074/jbc.RA120.014692   
2020 Sharma AN, Grandinetti L, Johnson ER, St Maurice M, Bearne SL. Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center. Biochemistry. PMID 32786399 DOI: 10.1021/acs.biochem.0c00478   
2020 Carretas-Valdez MI, Moreno-Cordova EN, Ibarra-Hernandez BG, Cinco-Moroyoqui FJ, Castillo-Yañez FJ, Casas-Flores S, Osuna-Amarillas PS, Islas-Osuna MA, Arvizu-Flores AA. Characterization of the trypsin-III from Monterey sardine (Sardinops caeruleus): Insights on the cold-adaptation from the A236N mutant. International Journal of Biological Macromolecules. PMID 32827617 DOI: 10.1016/j.ijbiomac.2020.08.136   
2020 Ishida T, Parks JM, Smith JC. Insight into the Catalytic Mechanism of GH11 Xylanase: Computational Analysis of Substrate Distortion based on a Neutron Structure. Journal of the American Chemical Society. PMID 32959658 DOI: 10.1021/jacs.0c02148   
2020 Kondo H, Kitagawa M, Matsumoto Y, Saito M, Amano M, Sugiyama S, Tamura T, Kusakabe H, Inagaki K, Imada K. Structural basis of strict substrate recognition of l-lysine α-oxidase from Trichoderma viride. Protein Science : a Publication of the Protein Society. PMID 32894626 DOI: 10.1002/pro.3946   
2020 Li Z, Zhu R, Liu Y, Li J, Gao H, Hu N. γ-Glutamyltranspeptidase from Bacillus amyloliquefaciens: transpeptidation activity enhancement and L-theanine production. Enzyme and Microbial Technology. 140: 109644. PMID 32912696 DOI: 10.1016/j.enzmictec.2020.109644   
2020 An X, Chen C, Wang T, Huang A, Zhang D, Han MJ, Wang J. Genetic Incorporation of Selenotyrosine Significantly Improves Enzymatic Activity of Agrobacterium radiobacter Phosphotriesterase. Chembiochem : a European Journal of Chemical Biology. PMID 32789938 DOI: 10.1002/cbic.202000460   
2020 Risso VA, Romero-Rivera A, Gutierrez-Rus LI, Ortega-Muñoz M, Santoyo-Gonzalez F, Gavira JA, Sanchez-Ruiz JM, Kamerlin SCL. Enhancing a enzyme activity by computationally-focused ultra-low-throughput screening. Chemical Science. 11: 6134-6148. PMID 32832059 DOI: 10.1039/d0sc01935f   
2020 Rachadech W, Kato Y, Abou El-Magd RM, Shishido Y, Kim SH, Sogabe H, Maita N, Yorita K, Fukui K. P219L substitution in human D-amino acid oxidase impacts the ligand binding and catalytic efficiency. Journal of Biochemistry. PMID 32730563 DOI: 10.1093/jb/mvaa083   
2020 Yang J, Ma T, Shang-Guan F, Han Z. Improving the catalytic activity of thermostable xylanase from Thermotoga maritima via mutagenesis of non-catalytic residues at glycone subsites. Enzyme and Microbial Technology. 139: 109579. PMID 32732029 DOI: 10.1016/j.enzmictec.2020.109579   
2020 Zhang Y, Yang J, Yu X, Hu X, Zhang H. Engineering Leuconostoc mesenteroides dextransucrase by inserting disulfide bridges for enhanced thermotolerance. Enzyme and Microbial Technology. 139: 109603. PMID 32732025 DOI: 10.1016/j.enzmictec.2020.109603   
2020 Watanabe S, Watanabe Y, Nobuchi R, Ono A. Biochemical and structural characterization of L-2-keto-3-deoxyarabinonate dehydratase: A unique catalytic mechanism in the Class I aldolase protein superfamily. Biochemistry. PMID 32697085 DOI: 10.1021/acs.biochem.0c00515   
2020 Peskin AV, Meotti FC, de Souza LF, Anderson RF, Winterbourn CC, Salvador A. Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2. Free Radical Biology & Medicine. PMID 32702382 DOI: 10.1016/j.freeradbiomed.2020.07.007   
2020 Tran KN, Jang SH, Lee C. Effect of active-site aromatic residues Tyr or Phe on activity and stability of glucose 6-phosphate dehydrogenase from psychrophilic Arctic bacterium Sphingomonas sp. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140543. PMID 32966894 DOI: 10.1016/j.bbapap.2020.140543   
2020 Kirk ML, Kc K. Molybdenum and Tungsten Cofactors and the Reactions They Catalyze. Metal Ions in Life Sciences. 20. PMID 32851830 DOI: 10.1515/9783110589757-015   
2020 Jaafar NR, Khoiri NM, Ismail NF, Mahmood NAN, Abdul Murad AM, Abu Bakar FD, Mat Yajit NL, Illias RM. Functional characterisation and product specificity of Endo-β-1,3-glucanase from alkalophilic bacterium, Bacillus lehensis G1. Enzyme and Microbial Technology. 140: 109625. PMID 32912685 DOI: 10.1016/j.enzmictec.2020.109625   
2020 Han QY, Liu F, Wen X, Ni YY. Kinetic, spectroscopic, and molecular docking studies on the inhibition of membrane-bound polyphenol oxidase from Granny Smith apples (Malus domestica Borkh.). Food Chemistry. 338: 127928. PMID 32919374 DOI: 10.1016/j.foodchem.2020.127928   
2020 Prah A, Purg M, Stare J, Vianello R, Mavri J. How Monoamine Oxidase A Decomposes Serotonin: An Empirical Valence Bond Simulation of the Reactive Step. The Journal of Physical Chemistry. B. PMID 32845149 DOI: 10.1021/acs.jpcb.0c06502   
2020 Shende VV, Khatri Y, Newmister SA, Sanders J, Lindovska P, Yu F, Doyon T, Kim J, Houk KN, Movassaghi M, Sherman DH. Structure and Function of NzeB, a Versatile C-C and C-N Bond Forming Diketopiperazine Dimerase. Journal of the American Chemical Society. PMID 32786740 DOI: 10.1021/jacs.0c06312   
2020 Conte JV, Frantom PA. Biochemical characterization of 2-phosphinomethylmalate synthase from Streptomyces hygroscopicus: A member of the DRE-TIM metallolyase superfamily. Archives of Biochemistry and Biophysics. 108489. PMID 32697946 DOI: 10.1016/   
2020 Yi Z, Cai Z, Zeng B, Zeng R, Zhang G. Identification and Characterization of a Novel Thermostable and Salt-Tolerant β-1,3 Xylanase from Strain WPAGA1. Biomolecules. 10. PMID 32906756 DOI: 10.3390/biom10091287   
2020 Shekhar H, Kant G, Tripathi R, Sharma S, Mani A, Singh NK, Srivastava S. Structural insight of two 4-Coumarate CoA ligase () isoforms in suggests targeted genetic manipulations could lead to better lignin extractability from the pulp. 3 Biotech. 10: 383. PMID 32802725 DOI: 10.1007/s13205-020-02375-2   
2020 Li J, Min J, Wang Y, Chen W, Kong Y, Guo T, Mahto JK, Sylvestre M, Hu X. Engineering LB400 through site directed mutagenesis at site 283. Applied and Environmental Microbiology. PMID 32709719 DOI: 10.1128/AEM.01040-20   
2020 Parikh SJ, Evans CM, Obi JO, Zhang Q, Maekawa K, Glass KC, Shah MB. Structure of cytochrome P450 2C9*2 in complex with an anti-hypertensive drug losartan: Insights into the effect of genetic polymorphism. Molecular Pharmacology. PMID 32938720 DOI: 10.1124/molpharm.120.000042   
2020 Wang B, Zhou Z, Jin X, Li J, Shi Z, Kang Z. [Expression optimization and molecular modification of heparin C5 epimerase]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 36: 1450-1458. PMID 32748603 DOI: 10.13345/j.cjb.190516   
2020 Alahuhta M, Himmel ME, Bomble YJ, Lunin VV. Crystallography of Metabolic Enzymes. Methods in Molecular Biology (Clifton, N.J.). 2096: 125-139. PMID 32720151 DOI: 10.1007/978-1-0716-0195-2_10   
2020 Senga A, Numoto N, Yamashita M, Iida A, Ito N, Kawai F, Oda M. Multiple structural states of Ca2+ regulated PET hydrolase, Cut190, and its correlation with activity and stability. Journal of Biochemistry. PMID 32882044 DOI: 10.1093/jb/mvaa102   
2020 Liao L, Zhou Y, Peng T, Guo Y, Zhao Y, Zeng Z. Crystal structure of a SAM-dependent O-methyltransferase-like enzyme from Aspergillus flavus. Proteins. PMID 32875607 DOI: 10.1002/prot.26004   
2020 Patil PR, Vithani N, Singh V, Kumar A, Prakash B. A revised mechanism for (p)ppGpp synthesis by Rel proteins: The critical role of the 2'-OH of GTP. The Journal of Biological Chemistry. PMID 32719004 DOI: 10.1074/jbc.RA120.013636   
2020 Dodda SR, Sarkar N, Jain P, Aikat K, Mukhopadhyay SS. Improved catalytic activity and stability of cellobiohydrolase (Cel6A) from the Aspergillus fumigatus by rational design. Protein Engineering, Design & Selection : Peds. 33. PMID 32930798 DOI: 10.1093/protein/gzaa020   
2020 Imamura K, Matsuura T, Nakagawa A, Kitamura S, Kusunoki M, Takaha T, Unno H. Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Science : a Publication of the Protein Society. PMID 32808707 DOI: 10.1002/pro.3932   
2020 Patel S, Smith T, Morton MD, Stiers K, Seravalli J, Mayclin S, Edwards T, Tanner JJ, Becker DF. Cautionary tale of using tris(alkyl)phosphine reducing agents with NAD-dependent enzymes. Biochemistry. PMID 32841567 DOI: 10.1021/acs.biochem.0c00490   
2020 Wantuch PL, Jella S, Duke JA, Mousa JJ, Henrissat B, Glushka J, Avci FY. Characterization of the β-glucuronidase Pn3Pase as the founding member of glycoside hydrolase family GH169. Glycobiology. PMID 32810871 DOI: 10.1093/glycob/cwaa070   
2020 Bathellier C, Yu LJ, Farquhar GD, Coote ML, Lorimer GH, Tcherkez G. Ribulose 1,5-bisphosphate carboxylase/oxygenase activates O by electron transfer. Proceedings of the National Academy of Sciences of the United States of America. PMID 32934141 DOI: 10.1073/pnas.2008824117   
2020 Muñoz-Bacasehua C, Rosas-Rodríguez JA, Arvizu-Flores AA, Stephens-Camacho A, Soñanez-Organis JG, Figueroa-Soto CG, Valenzuela-Soto EM. Heterogeneity of active sites in recombinant betaine aldehyde dehydrogenase is modulated by potassium. Journal of Molecular Recognition : Jmr. 33: e2869. PMID 32881113 DOI: 10.1002/jmr.2869   
2020 Lee SG, Harline K, Abar O, Akadri SO, Bastian AG, Chen HS, Duan M, Focht CM, Groziak AR, Kao J, Kottapalli JS, Leong MC, Lin JJ, Liu R, Luo JE, et al. The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase. The Journal of Biological Chemistry. PMID 32796031 DOI: 10.1074/jbc.RA120.014747   
2020 Hecht N, Monteil CL, Perrière G, Vishkautzan M, Gur E. Exploring protein space: From hydrolase to ligase by substitution. Molecular Biology and Evolution. PMID 32870983 DOI: 10.1093/molbev/msaa215   
2020 Xue J, Wang P, Kuang J, Zhu Y. Computational design of new enzymes for hydrolysis and synthesis of third-generation cephalosporin antibiotics. Enzyme and Microbial Technology. 140: 109649. PMID 32912699 DOI: 10.1016/j.enzmictec.2020.109649   
2020 Hoque MA, Zhang Y, Li Z, Cui L, Feng Y. Remodeling enzyme active sites by stepwise loop insertion. Methods in Enzymology. 643: 111-127. PMID 32896277 DOI: 10.1016/bs.mie.2020.07.008   
2020 Stokes ES, Gilchrist ML, Calhoun DH. Prediction of improved therapeutics for fabry disease patients generated by mutagenesis of the α-galactosidase A active site, dimer interface, and glycosylation region. Protein Expression and Purification. 175: 105710. PMID 32738442 DOI: 10.1016/j.pep.2020.105710   
2020 Tormet-González GD, Wilson C, de Oliveira GS, Dos Santos JC, de Oliveira LG, Dias MVB. An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity. Acta Crystallographica. Section D, Structural Biology. 76: 868-875. PMID 32876062 DOI: 10.1107/S2059798320010402   
2020 Bisello G, Longo C, Rossignoli G, Phillips RS, Bertoldi M. Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance. Amino Acids. PMID 32844248 DOI: 10.1007/s00726-020-02885-6   
2020 Prejanò M, Romeo I, Russo N, Marino T. On the Catalytic Activity of the Engineered Coiled-Coil Heptamer Mimicking the Hydrolase Enzymes: Insights from a Computational Study. International Journal of Molecular Sciences. 21. PMID 32604744 DOI: 10.3390/ijms21124551   
2020 Tang J, Ju Y, Zhou J, Guo J, Gu Q, Xu J, Zhou H. Structural and biochemical characterization of SbnC as a representative type B siderophore synthetase. Acs Chemical Biology. PMID 32880431 DOI: 10.1021/acschembio.0c00523   
2020 Wyatt JW, Korasick DA, Qureshi IA, Campbell AC, Gates KS, Tanner JJ. Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1. Archives of Biochemistry and Biophysics. 108477. PMID 32717224 DOI: 10.1016/   
2020 Kim V, Lim YR, Lee I, Lee JH, Han S, Pham TV, Kim H, Lee R, Kang LW, Kim D. Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Archives of Biochemistry and Biophysics. 108544. PMID 32822639 DOI: 10.1016/   
2020 Okuda M, Ozawa T, Kawahara A, Takimura Y. The hydrophobicity of an amino acid residue in a flexible loop of KP-43 protease alters activity toward a macromolecule substrate. Applied Microbiology and Biotechnology. PMID 32840642 DOI: 10.1007/s00253-020-10826-2   
2020 Wang L, Yang L, Feng YL, Zhang H. Evolutionary insights into the active-site structures of the metallo-β-lactamase superfamily from a classification study with support vector machine. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 32945939 DOI: 10.1007/s00775-020-01822-y   
2020 Wang L, Yang L, Feng YL, Zhang H. Evolutionary insights into the active-site structures of the metallo-β-lactamase superfamily from a classification study with support vector machine. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 32945939 DOI: 10.1007/s00775-020-01822-y