Varghese John - Publications

Affiliations: 
Neurology David Geffen School of Medicine at UCLA, Los Angeles, CA, United States 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Duong AT, Simmons BJ, Alam MP, Campagna J, Garg NK, John V. Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor. Tetrahedron Letters. 60: 322-326. PMID 30631216 DOI: 10.1016/j.tetlet.2018.12.045  0.36
2018 Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V. A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model. Scientific Reports. 8: 17574. PMID 30514854 DOI: 10.1038/s41598-018-35687-8  0.36
2018 Campagna J, Vadivel K, Jagodzinska B, Jun M, Bilousova T, Spilman P, John V. Evaluation of an Allosteric BACE inhibitor peptide to identify mimetics that can interact with the Loop F Region of the enzyme and prevent APP cleavage. Journal of Molecular Biology. PMID 29649434 DOI: 10.1016/j.jmb.2018.04.002  0.36
2018 Bilousova T, Elias C, Miyoshi E, Alam MP, Zhu C, Campagna J, Vadivel K, Jagodzinska B, Gylys K, John V. Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2. Biochemical and Biophysical Research Communications. PMID 29604274 DOI: 10.1016/j.bbrc.2018.03.209  0.36
2018 Shkhyan R, Van Handel B, Bogdanov J, Lee S, Yu Y, Scheinberg M, Banks NW, Limfat S, Chernostrik A, Franciozi CE, Alam MP, John V, Wu L, Ferguson GB, Nsair A, et al. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair. Annals of the Rheumatic Diseases. PMID 29436471 DOI: 10.1136/annrheumdis-2017-212037  0.36
2017 Alam MP, Bilousova T, Spilman P, Vadivel K, Bai D, Evseenko D, John V. A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity. Acs Chemical Neuroscience. PMID 29161500 DOI: 10.1021/acschemneuro.7b00350  0.36
2017 Subbiah N, Campagna J, Spilman P, Alam MP, Sharma S, Hokugo A, Nishimura I, John V. Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. Journal of Drug Delivery. 2017: 4759839. PMID 28480080 DOI: 10.1155/2017/4759839  0.36
2017 Poksay KS, Sheffler DJ, Spilman P, Campagna J, Jagodzinska B, Descamps O, Gorostiza O, Matalis A, Mullenix M, Bredesen DE, Cosford ND, John V. Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production. Frontiers in Pharmacology. 8: 46. PMID 28261092 DOI: 10.3389/fphar.2017.00046  0.36
2016 Heinzelman P, Bilousova T, Campagna J, John V. Nanoscale Extracellular Vesicle Analysis in Alzheimer's Disease Diagnosis and Therapy. International Journal of Alzheimer's Disease. 2016: 8053139. PMID 27213078 DOI: 10.1155/2016/8053139  0.36
2016 Alam MP, Jagodzinska B, Campagna J, Spilman P, John V. C-O bond Formation in a Microfluidic Reactor: High Yield SNAr Substitution of Heteroaryl Chlorides. Tetrahedron Letters. 57: 2059-2062. PMID 27152054 DOI: 10.1016/j.tetlet.2016.03.095  0.36
2016 Spilman PR, Corset V, Gorostiza O, Poksay KS, Galvan V, Zhang J, Rao R, Peters-Libeu C, Vincelette J, McGeehan A, Dvorak-Ewell M, Beyer J, Campagna J, Bankiewicz K, Mehlen P, ... John V, et al. Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27060954 DOI: 10.3233/JAD-151046  0.36
2015 Peters-Libeu C, Campagna J, Mitsumori M, Poksay KS, Spilman P, Sabogal A, Bredesen DE, John V. sAβPPα is a Potent Endogenous Inhibitor of BACE1. Journal of Alzheimer's Disease : Jad. 47: 545-55. PMID 26401691 DOI: 10.3233/JAD-150282  0.36
2014 Zhang Q, Descamps O, Hart MJ, Poksay KS, Spilman P, Kane DJ, Gorostiza O, John V, Bredesen DE. Paradoxical effect of TrkA inhibition in Alzheimer's disease models. Journal of Alzheimer's Disease : Jad. 40: 605-17. PMID 24531152 DOI: 10.3233/JAD-130017  0.36
2014 Spilman P, Descamps O, Gorostiza O, Peters-Libeu C, Poksay KS, Matalis A, Campagna J, Patent A, Rao R, John V, Bredesen DE. The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model. Brain Research. 1551: 25-44. PMID 24389031 DOI: 10.1016/j.brainres.2013.12.029  0.36
2013 Descamps O, Spilman P, Zhang Q, Libeu CP, Poksay K, Gorostiza O, Campagna J, Jagodzinska B, Bredesen DE, John V. AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 343-55. PMID 23948888 DOI: 10.3233/JAD-130578  0.36
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