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R. Ariel Igal - Publications

Affiliations: 
1998 Nutrition University of North Carolina, Chapel Hill, Chapel Hill, NC 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Igal RA. Death and the desaturase: Implication of Stearoyl-CoA desaturase-1 in the mechanisms of cell stress, apoptosis, and ferroptosis. Biochimie. 225: 156-167. PMID 38823621 DOI: 10.1016/j.biochi.2024.05.023  0.48
2020 Igal RA, Sinner DI. Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1866: 158840. PMID 33049404 DOI: 10.1016/j.bbalip.2020.158840  0.443
2016 Igal RA. Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism. Biochimica Et Biophysica Acta. 1861: 1865-1880. PMID 27639967 DOI: 10.1016/j.bbalip.2016.09.009  0.428
2011 Igal RA. Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis. Cancers. 3: 2462-77. PMID 24212819 DOI: 10.3390/cancers3022462  0.455
2011 Hess D, Igal RA. Genistein downregulates de novo lipid synthesis and impairs cell proliferation in human lung cancer cells. Experimental Biology and Medicine (Maywood, N.J.). 236: 707-13. PMID 21565896 DOI: 10.1258/ebm.2011.010265  0.409
2010 Hess D, Chisholm JW, Igal RA. Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. Plos One. 5: e11394. PMID 20613975 DOI: 10.1371/journal.pone.0011394  0.459
2010 Igal RA. Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer. Carcinogenesis. 31: 1509-15. PMID 20595235 DOI: 10.1093/carcin/bgq131  0.456
2009 Scaglia N, Chisholm JW, Igal RA. Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK. Plos One. 4: e6812. PMID 19710915 DOI: 10.1371/journal.pone.0006812  0.384
2009 Maeda M, Scaglia N, Igal RA. Regulation of fatty acid synthesis and Delta9-desaturation in senescence of human fibroblasts. Life Sciences. 84: 119-24. PMID 19059270 DOI: 10.1016/j.lfs.2008.11.009  0.431
2008 Scaglia N, Igal RA. Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis. International Journal of Oncology. 33: 839-50. PMID 18813799  0.389
2005 Scaglia N, Igal RA. Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells. The Journal of Biological Chemistry. 280: 25339-49. PMID 15851470 DOI: 10.1074/jbc.M501159200  0.552
2005 Scaglia N, Caviglia JM, Igal RA. High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts. Biochimica Et Biophysica Acta. 1687: 141-51. PMID 15708362 DOI: 10.1016/j.bbalip.2004.11.015  0.405
2004 Caviglia JM, De Gómez Dumm IN, Coleman RA, Igal RA. Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells. Journal of Lipid Research. 45: 1500-9. PMID 15175356 DOI: 10.1194/Jlr.M400079-Jlr200  0.581
2003 Bagnato C, Igal RA. Overexpression of diacylglycerol acyltransferase-1 reduces phospholipid synthesis, proliferation, and invasiveness in simian virus 40-transformed human lung fibroblasts. The Journal of Biological Chemistry. 278: 52203-11. PMID 14557275 DOI: 10.1074/jbc.M305760200  0.518
2001 Igal RA, Wang S, Gonzalez-Baró M, Coleman RA. Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol. The Journal of Biological Chemistry. 276: 42205-12. PMID 11546763 DOI: 10.1074/Jbc.M103386200  0.593
2001 Igal RA, Caviglia JM, de Gómez Dumm IN, Coleman RA. Diacylglycerol generated in CHO cell plasma membrane by phospholipase C is used for triacylglycerol synthesis. Journal of Lipid Research. 42: 88-95. PMID 11160369  0.399
1998 Igal RA, de Gómez Dumm IN, Goya RG. Modulation of rat liver lipid metabolism by prolactin. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 59: 395-400. PMID 10102385  0.432
1998 de Gomez Dumm IN, Montenegro S, Tarrés MC, Martinez SM, Igal RA. Early lipid alterations in spontaneously diabetic rats. Acta Physiologica, Pharmacologica Et Therapeutica Latinoamericana : ÓRgano De La AsociacióN Latinoamericana De Ciencias FisiolóGicas Y [De] La AsociacióN Latinoamericana De FarmacologíA. 48: 228-34. PMID 9914813  0.302
1998 Igal RA, Coleman RA. Neutral lipid storage disease: a genetic disorder with abnormalities in the regulation of phospholipid metabolism. Journal of Lipid Research. 39: 31-43. PMID 9469583  0.557
1997 Igal RA, Rhoads JM, Coleman RA. Neutral lipid storage disease with fatty liver and cholestasis. Journal of Pediatric Gastroenterology and Nutrition. 25: 541-7. PMID 9360211 DOI: 10.1097/00005176-199711000-00011  0.503
1997 Igal RA, Wang P, Coleman RA. Triacsin C blocks de novo synthesis of glycerolipids and cholesterol esters but not recycling of fatty acid into phospholipid: evidence for functionally separate pools of acyl-CoA. The Biochemical Journal. 324: 529-34. PMID 9182714 DOI: 10.1042/Bj3240529  0.613
1996 Igal RA, Coleman RA. Acylglycerol recycling from triacylglycerol to phospholipid, not lipase activity, is defective in neutral lipid storage disease fibroblasts. The Journal of Biological Chemistry. 271: 16644-51. PMID 8663220 DOI: 10.1074/Jbc.271.28.16644  0.612
1991 Igal RA, Mandon EC, de Gómez Dumm IN. Abnormal metabolism of polyunsaturated fatty acids in adrenal glands of diabetic rats. Molecular and Cellular Endocrinology. 77: 217-27. PMID 1840041  0.36
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