Jeffrey S. Nye - Publications

Molecular Pharmacology and Biological Chemistry Northwestern University, Evanston, IL 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Prins ND, van der Flier WA, Knol DL, Fox NC, Brashear HR, Nye JS, Barkhof F, Scheltens P. The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial. Alzheimer's Research & Therapy. 6: 47. PMID 25478019 DOI: 10.1186/Alzrt275  0.32
2014 Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS. Alzheimer's disease research and development: a call for a new research roadmap. Annals of the New York Academy of Sciences. 1313: 1-16. PMID 24754377 DOI: 10.1111/Nyas.12424  0.32
2014 Hager K, Baseman AS, Nye JS, Brashear HR, Han J, Sano M, Davis B, Richards HM. Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease. Neuropsychiatric Disease and Treatment. 10: 391-401. PMID 24591834 DOI: 10.2147/NDT.S57909  0.32
2014 Di Prospero NA, Gambale JJ, Pandina G, Ford L, Girgis S, Moyer JA, Xi L, Nye JS, Kasteleijn-Nolst Trenité D. Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: a placebo-controlled, exploratory study. Epilepsy Research. 108: 709-16. PMID 24560845 DOI: 10.1016/j.eplepsyres.2014.01.018  0.32
2013 Tobe BT, Brandel MG, Nye JS, Snyder EY. Implications and limitations of cellular reprogramming for psychiatric drug development. Experimental & Molecular Medicine. 45: e59. PMID 24232258 DOI: 10.1038/Emm.2013.124  0.32
2011 Tobe BT, Snyder EY, Nye JS. Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells. Current Opinion in Pharmacology. 11: 521-7. PMID 21723195 DOI: 10.1016/J.Coph.2011.05.007  0.32
2008 Carter DB, Dunn E, Pauley AM, McKinley DD, Fleck TJ, Ellerbrook BR, Stratman NC, Zhou X, Himes CS, Nye JS, Tomasselli A, Yan R. Changes in gamma-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1. Molecular Neurodegeneration. 3: 6. PMID 18474109 DOI: 10.1186/1750-1326-3-6  0.32
2008 Winblad B, Gauthier S, Scinto L, Feldman H, Wilcock GK, Truyen L, Mayorga AJ, Wang D, Brashear HR, Nye JS. Safety and efficacy of galantamine in subjects with mild cognitive impairment. Neurology. 70: 2024-35. PMID 18322263 DOI: 10.1212/01.Wnl.0000303815.69777.26  0.32
2005 Yao C, Raoufinia A, Gold M, Nye JS, Ramael S, Padmanabhan M, Walschap Y, Verhaeghe T, Zhao Q. Steady-state pharmacokinetics of galantamine are not affected by addition of memantine in healthy subjects. Journal of Clinical Pharmacology. 45: 519-28. PMID 15831775 DOI: 10.1177/0091270005274551  0.32
2005 Sebold CD, Melvin EC, Siegel D, Mehltretter L, Enterline DS, Nye JS, Kessler J, Bassuk A, Speer MC, George TM. Recurrence risks for neural tube defects in siblings of patients with lipomyelomeningocele Genetics in Medicine. 7: 64-67. PMID 15654231 DOI: 10.1097/01.Gim.0000151158.09278.2B  0.32
2003 Li J, Fici GJ, Mao CA, Myers RL, Shuang R, Donoho GP, Pauley AM, Himes CS, Qin W, Kola I, Merchant KM, Nye JS. Positive and negative regulation of the gamma-secretase activity by nicastrin in a murine model. The Journal of Biological Chemistry. 278: 33445-9. PMID 12815056 DOI: 10.1074/jbc.M301288200  0.32
2002 Presente A, Shaw S, Nye JS, Andres AJ. Transgene-mediated RNA interference defines a novel role for notch in chemosensory startle behavior. Genesis (New York, N.Y. : 2000). 34: 165-9. PMID 12324975 DOI: 10.1002/Gene.10149  0.32
2002 Foltz D, Santiago MC, Berechid BE, Nye JS. Glycogen synthase kinase-3β modulates notch signaling and stability Current Biology. 12: 1006-1011. PMID 12123574 DOI: 10.1016/S0960-9822(02)00888-6  0.32
2002 Francis R, McGrath G, Zhang J, Ruddy DA, Sym M, Apfeld J, Nicoll M, Maxwell M, Hai B, Ellis MC, Parks AL, Xu W, Li J, Gurney M, Myers RL, ... ... Nye JS, et al. aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Developmental Cell. 3: 85-97. PMID 12110170 DOI: 10.1016/S1534-5807(02)00189-2  0.32
2002 Hitoshi S, Alexson T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes & Development. 16: 846-58. PMID 11937492 DOI: 10.1101/Gad.975202  0.32
2002 Berechid BE, Kitzmann M, Foltz DR, Roach AH, Seiffert D, Thompson LA, Olson RE, Bernstein A, Donoviel DB, Nye JS. Identification and characterization of presenilin-independent Notch signaling. The Journal of Biological Chemistry. 277: 8154-65. PMID 11756438 DOI: 10.1074/jbc.M108238200  0.32
2001 Presente A, Andres A, Nye JS. Requirement of Notch in adulthood for neurological function and longevity Neuroreport. 12: 3321-3325. PMID 11711879 DOI: 10.1097/00001756-200110290-00035  0.32
2001 Foltz DR, Nye JS. Hyperphosphorylation and association with RBP of the intracellular domain of Notch1. Biochemical and Biophysical Research Communications. 286: 484-92. PMID 11511084 DOI: 10.1006/Bbrc.2001.5421  0.52
2000 Gaiano N, Nye JS, Fishell G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron. 26: 395-404. PMID 10839358 DOI: 10.1016/S0896-6273(00)81172-1  0.32
2000 Palacino JJ, Berechid BE, Alexander P, Eckman C, Younkin S, Nye JS, Wolozin B. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. The Journal of Biological Chemistry. 275: 215-22. PMID 10617607 DOI: 10.1074/Jbc.275.1.215  0.32
1999 Berechid BE, Thinakaran G, Wong PC, Sisodia SS, Nye JS. Lack of requirement for presenilin1 in Notch1 signaling. Current Biology : Cb. 9: 1493-6. PMID 10607593 DOI: 10.1016/S0960-9822(00)80121-9  0.32
1999 Franklin JL, Berechid BE, Cutting FB, Presente A, Chambers CB, Foltz DR, Ferreira A, Nye JS. Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1. Current Biology : Cb. 9: 1448-57. PMID 10607588 DOI: 10.1016/S0960-9822(00)80114-1  0.32
1996 Kopan R, Schroeter EH, Weintraub H, Nye JS. Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proceedings of the National Academy of Sciences of the United States of America. 93: 1683-8. PMID 8643690 DOI: 10.1073/Pnas.93.4.1683  0.32
1995 Nye JS, Kopan R. Developmental signaling. Vertebrate ligands for Notch. Current Biology : Cb. 5: 966-9. PMID 8542284 DOI: 10.1016/S0960-9822(95)00189-8  0.32
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