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L.-C. Campeau - Publications

Affiliations: 
2007- Process Chemistry Merck & Co., Inc. 
Area:
Drug Discovery & Development
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Davison EK, Petrone DA, Meanwell M, Nodwell MB, Silverman SM, Campeau LC, Britton R. Practical and concise synthesis of nucleoside analogs. Nature Protocols. PMID 35788720 DOI: 10.1038/s41596-022-00705-7  0.337
2022 Gabbey AL, Michel NWM, Hughes JME, Campeau LC, Rousseaux SAL. Synthesis of α-Aryl Secondary Amides via Nickel-Catalyzed Reductive Coupling of Redox-Active Esters. Organic Letters. PMID 35471845 DOI: 10.1021/acs.orglett.2c00918  0.608
2021 Meanwell M, Fehr G, Ren W, Adluri B, Rose V, Lehmann J, Silverman SM, Rowshanpour R, Adamson C, Bergeron-Brlek M, Foy H, Challa VR, Campeau LC, Dudding T, Britton R. Diversity-oriented synthesis of glycomimetics. Communications Chemistry. 4: 96. PMID 36697548 DOI: 10.1038/s42004-021-00520-3  0.317
2021 Piou T, Campeau LC. Bringing amines back into aziridination. Nature Chemistry. 13: 1027-1028. PMID 34697398 DOI: 10.1038/s41557-021-00819-7  0.417
2021 Klapars A, Chung JYL, Limanto J, Calabria R, Campeau LC, Campos KR, Chen W, Dalby SM, Davis TA, DiRocco DA, Hyde AM, Kassim AM, Larsen MU, Liu G, Maligres PE, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chemical Science. 12: 9031-9036. PMID 34276931 DOI: 10.1039/d1sc01978c  0.368
2020 Meanwell M, Silverman SM, Lehmann J, Adluri B, Wang Y, Cohen R, Campeau LC, Britton R. A short de novo synthesis of nucleoside analogs. Science (New York, N.Y.). 369: 725-730. PMID 32764073 DOI: 10.1126/Science.Abb3231  0.413
2019 Campeau LC, Hazari N. Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future. Organometallics. 38: 3-35. PMID 31741548 DOI: 10.1021/acs.organomet.8b00720  0.461
2017 Ji Y, Li H, Hyde AM, Chen Q, Belyk KM, Lexa KW, Yin J, Sherer EC, Williamson RT, Brunskill A, Ren S, Campeau LC, Davies IW, Ruck RT. A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions. Chemical Science. 8: 2841-2851. PMID 28553522 DOI: 10.1039/C6Sc05472B  0.409
2017 DiRocco DA, Ji Y, Sherer EC, Klapars A, Reibarkh M, Dropinski J, Mathew R, Maligres P, Hyde AM, Limanto J, Brunskill A, Ruck RT, Campeau LC, Davies IW. A multifunctional catalyst that stereoselectively assembles prodrugs. Science (New York, N.Y.). 356: 426-430. PMID 28450641 DOI: 10.1126/Science.Aam7936  0.319
2016 Yayla HG, Peng F, Mangion IK, McLaughlin M, Campeau LC, Davies IW, DiRocco DA, Knowles RR. Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir. Chemical Science. 7: 2066-2073. PMID 29899932 DOI: 10.1039/C5Sc03350K  0.309
2016 Kutchukian PS, Dropinski JF, Dykstra KD, Li B, DiRocco DA, Streckfuss EC, Campeau LC, Cernak T, Vachal P, Davies IW, Krska SW, Dreher SD. Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods. Chemical Science. 7: 2604-2613. PMID 28660032 DOI: 10.1039/C5Sc04751J  0.304
2016 Joshi-Pangu A, Lévesque F, Roth HG, Oliver SF, Campeau LC, Nicewicz D, DiRocco DA. Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis. The Journal of Organic Chemistry. PMID 27454776 DOI: 10.1021/Acs.Joc.6B01240  0.332
2016 Williams MJ, Kong J, Chung CK, Brunskill A, Campeau LC, McLaughlin M. The Discovery of Quinoxaline-Based Metathesis Catalysts from Synthesis of Grazoprevir (MK-5172). Organic Letters. PMID 27123552 DOI: 10.1021/Acs.Orglett.6B00070  0.337
2016 Shevlin M, Friedfeld MR, Sheng H, Pierson NA, Hoyt JM, Campeau LC, Chirik PJ. Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,β-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation. Journal of the American Chemical Society. PMID 26890979 DOI: 10.1021/Jacs.6B00519  0.381
2016 Friedfeld MR, Shevlin M, Margulieux GW, Campeau LC, Chirik PJ. Cobalt-Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences. Journal of the American Chemical Society. PMID 26854359 DOI: 10.1021/Jacs.5B10148  0.362
2016 Kutchukian PS, Dropinski JF, Dykstra KD, Li B, Dirocco DA, Streckfuss EC, Campeau LC, Cernak T, Vachal P, Davies IW, Krska SW, Dreher SD. Chemistry informer libraries: A chemoinformatics enabled approach to evaluate and advance synthetic methods Chemical Science. 7: 2604-2613. DOI: 10.1039/c5sc04751j  0.305
2016 Yayla HG, Peng F, Mangion IK, McLaughlin M, Campeau LC, Davies IW, Dirocco DA, Knowles RR. Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir Chemical Science. 7: 2066-2073. DOI: 10.1039/c5sc03350k  0.324
2015 Halperin SD, Kwon D, Holmes M, Regalado EL, Campeau LC, DiRocco DA, Britton R. Development of a Direct Photocatalytic C-H Fluorination for the Preparative Synthesis of Odanacatib. Organic Letters. 17: 5200-3. PMID 26484983 DOI: 10.1021/Acs.Orglett.5B02532  0.376
2015 Li H, Belyk KM, Yin J, Chen Q, Hyde A, Ji Y, Oliver S, Tudge MT, Campeau LC, Campos KR. Enantioselective Synthesis of Hemiaminals via Pd-Catalyzed C-N Coupling with Chiral Bisphosphine Mono-Oxides. Journal of the American Chemical Society. PMID 26414910 DOI: 10.1021/jacs.5b05934  0.422
2015 Buitrago Santanilla A, Christensen M, Campeau LC, Davies IW, Dreher SD. P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C-N, C-O, and C-C Cross-Coupling Reactions. Organic Letters. PMID 26099020 DOI: 10.1021/acs.orglett.5b01648  0.346
2015 Buitrago Santanilla A, Regalado EL, Pereira T, Shevlin M, Bateman K, Campeau LC, Schneeweis J, Berritt S, Shi ZC, Nantermet P, Liu Y, Helmy R, Welch CJ, Vachal P, Davies IW, et al. Organic chemistry. Nanomole-scale high-throughput chemistry for the synthesis of complex molecules. Science (New York, N.Y.). 347: 49-53. PMID 25554781 DOI: 10.1126/Science.1259203  0.416
2014 McCabe Dunn JM, Kuethe JT, Orr RK, Tudge M, Campeau LC. Development of a palladium-catalyzed α-arylation of cyclopropyl nitriles. Organic Letters. 16: 6314-7. PMID 25474721 DOI: 10.1021/ol5030426  0.438
2010 Sun HY, Gorelsky SI, Stuart DR, Campeau LC, Fagnou K. Mechanistic analysis of azine N-oxide direct arylation: evidence for a critical role of acetate in the Pd(OAc)2 precatalyst. The Journal of Organic Chemistry. 75: 8180-9. PMID 21053903 DOI: 10.1021/Jo101821R  0.695
2010 Sun HY, Gorelsky SI, Stuart DR, Campeau LC, Fagnou K. Mechanistic analysis of azine N-oxide direct arylation: Evidence for a critical role of acetate in the Pd(OAc)2 precatalyst Journal of Organic Chemistry. 75: 8180-8189. DOI: 10.1021/jo101821r  0.603
2009 Campeau LC, Stuart DR, Leclerc JP, Bertrand-Laperle M, Villemure E, Sun HY, Lasserre S, Guimond N, Lecavallier M, Fagnou K. Palladium-catalyzed direct arylation of azine and azole N-oxides: Reaction development, scope and applications in synthesis Journal of the American Chemical Society. 131: 3291-3306. PMID 19215128 DOI: 10.1021/Ja808332K  0.724
2009 Schipper DJ, Campeau LC, Fagnou K. Catalyst and base controlled site-selective sp2 and sp3 direct arylation of azine N-oxides Tetrahedron. 65: 3155-3164. DOI: 10.1016/J.Tet.2008.12.004  0.755
2009 Schipper DJ, Campeau L, Fagnou K. ChemInform Abstract: Catalyst and Base Controlled Site-Selective sp2and sp3Direct Arylation of Azine N-Oxides. Cheminform. 40. DOI: 10.1002/CHIN.200932097  0.645
2008 Caron L, Campeau LC, Fagnou K. Palladium-catalyzed direct arylation of nitro-substituted aromatics with aryl halides. Organic Letters. 10: 4533-6. PMID 18811176 DOI: 10.1021/Ol801839W  0.741
2008 Campeau LC, Bertrand-Laperle M, Leclerc JP, Villemure E, Gorelsky S, Fagnou K. C2, C5, and C4 azole N-oxide direct arylation including room-temperature reactions Journal of the American Chemical Society. 130: 3276-3277. PMID 18302383 DOI: 10.1021/Ja7107068  0.606
2008 Campeau LC, Schipper DJ, Fagnou K. Site-selective sp2 and benzylic sp3 palladium-catalyzed direct arylation. Journal of the American Chemical Society. 130: 3266-7. PMID 18293986 DOI: 10.1021/Ja710451S  0.739
2008 Caron L, Campeau LC, Fagnou K. Palladium-catalyzed direct arylation of nitro-substituted aromatics with aryl halides Organic Letters. 10: 4533-4536. DOI: 10.1021/ol801839w  0.726
2007 Campeau LC, Fagnou K. Applications of and alternatives to π-electron-deficient azine organometallics in metal catalyzed cross-coupling reactions Chemical Society Reviews. 36: 1058-1068. PMID 17576474 DOI: 10.1039/B616082D  0.642
2006 Campeau LC, Fagnou K. Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules Chemical Communications. 1253-1264. PMID 16538241 DOI: 10.1039/B515481M  0.728
2006 Campeau LC, Parisien M, Jean A, Fagnou K. Catalytic direct arylation with aryl chlorides, bromides, and iodides: intramolecular studies leading to new intermolecular reactions. Journal of the American Chemical Society. 128: 581-90. PMID 16402846 DOI: 10.1021/Ja055819X  0.757
2006 Campeau LC, Parisien M, Jean A, Fagnou K. Catalytic direct arylation with aryl chlorides, bromides, and iodides: Intramolecular studies leading to new intermolecular reactions Journal of the American Chemical Society. 128: 581-590. DOI: 10.1021/ja055819x  0.738
2005 Campeau LC, Rousseaux S, Fagnou K. A solution to the 2-pyridyl organometallic cross-coupling problem: regioselective catalytic direct arylation of pyridine N-oxides. Journal of the American Chemical Society. 127: 18020-1. PMID 16366550 DOI: 10.1021/Ja056800X  0.752
2005 Campeau LC, Thansandote P, Fagnou K. High-yielding intramolecular direct arylation reactions with aryl chlorides. Organic Letters. 7: 1857-60. PMID 15844924 DOI: 10.1021/Ol050501V  0.752
2005 Campeau LC, Thansandote P, Fagnou K. High-yielding intramolecular direct arylation reactions with aryl chlorides Organic Letters. 7: 1857-1860. DOI: 10.1021/ol050501v  0.725
2004 Campeau LC, Parisien M, Leblanc M, Fagnou K. Biaryl synthesis via direct arylation: establishment of an efficient catalyst for intramolecular processes. Journal of the American Chemical Society. 126: 9186-7. PMID 15281800 DOI: 10.1021/Ja049017Y  0.659
2004 Campeau LC, Parisien M, Leblanc M, Fagnou K. Biaryl synthesis via direct arylation: Establishment of an efficient catalyst for intramolecular processes Journal of the American Chemical Society. 126: 9186-9187. DOI: 10.1021/ja049017y  0.65
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