Michael Shultz - Publications

Purdue University, West Lafayette, IN, United States 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Shapiro BA, Vu NT, Shultz MD, Shultz JC, Mietla JA, Gouda MM, Yacoub A, Dent P, Fisher PB, Park MA, Chalfant CE. Melanoma differentiation associated gene 7/IL-24 exerts cytotoxic effects by altering the alternative splicing of Bcl-x pre-mRNA via the SRC/PKCδ signaling axis. The Journal of Biological Chemistry. PMID 27519412 DOI: 10.1074/jbc.M116.737569  0.6
2016 Chen YP, LaMarche MJ, Chan HM, Fekkes P, Garcia-Fortanet J, Acker MG, Antonakos B, Chen CH, Chen Z, Cooke VG, Dobson JR, Deng Z, Fei F, Firestone B, Fodor M, ... ... Shultz MD, et al. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature. PMID 27362227 DOI: 10.1038/nature18621  0.6
2016 Garcia Fortanet J, Chen CH, Chen YP, Chen Z, Deng Z, Firestone B, Fekkes P, Fodor M, Fortin PD, Fridrich C, Grunenfelder D, Ho S, Kang ZB, Karki R, Kato M, ... ... Shultz MD, et al. Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor. Journal of Medicinal Chemistry. PMID 27347692 DOI: 10.1021/acs.jmedchem.6b00680  0.6
2016 Spence S, Deurinck M, Ju H, Traebert M, McLean L, Marlowe J, Emotte C, Tritto E, Tseng M, Shultz M, Friedrichs GS. Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27255383 DOI: 10.1093/toxsci/kfw104  0.6
2016 Vu NT, Park MA, Shultz MD, Bulut GB, Ladd AC, Chalfant CE. Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis. Cancer Research. 76: 2977-2989. PMID 27197231 DOI: 10.1158/0008-5472.CAN-15-2512  0.6
2014 Shultz MD. Improving the plausibility of success with inefficient metrics Acs Medicinal Chemistry Letters. 5: 2-5. DOI: 10.1021/ml4004638  0.6
2013 Fatouros PP, Shultz MD. Metallofullerenes: A new class of MRI agents and more? Nanomedicine. 8: 1853-1864. PMID 24156489 DOI: 10.2217/nnm.13.160  0.6
2013 Shultz MD. The thermodynamic basis for the use of lipophilic efficiency (LipE) in enthalpic optimizations Bioorganic and Medicinal Chemistry Letters. 23: 5992-6000. PMID 24054120 DOI: 10.1016/j.bmcl.2013.08.030  0.6
2013 Shultz MD. Setting expectations in molecular optimizations: Strengths and limitations of commonly used composite parameters Bioorganic and Medicinal Chemistry Letters. 23: 5980-5991. PMID 24018190 DOI: 10.1016/j.bmcl.2013.08.029  0.6
2013 Shultz MD, Majumdar D, Chin DN, Fortin PD, Feng Y, Gould T, Kirby CA, Stams T, Waters NJ, Shao W. Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases Journal of Medicinal Chemistry. 56: 7049-7059. PMID 23879431 DOI: 10.1021/jm400826j  0.6
2013 Shultz MD, Cheung AK, Kirby CA, Firestone B, Fan J, Chen CH, Chen Z, Chin DN, Dipietro L, Fazal A, Feng Y, Fortin PD, Gould T, Lagu B, Lei H, et al. Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor. Journal of Medicinal Chemistry. 56: 6495-511. PMID 23844574 DOI: 10.1021/jm400807n  0.6
2013 Mietla JA, Wijesinghe DS, Hoeferlin LA, Shultz MD, Natarajan R, Fowler AA, Chalfant CE. Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase Journal of Lipid Research. 54: 1834-1847. PMID 23576683 DOI: 10.1194/jlr.M035683  0.6
2013 Vu NT, Park MA, Shultz JC, Goehe RW, Hoeferlin LA, Shultz MD, Smith SA, Lynch KW, Chalfant CE. HnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L Journal of Biological Chemistry. 288: 8575-8584. PMID 23396972 DOI: 10.1074/jbc.M112.443333  0.6
2012 Wilson JD, Broaddus WC, Dorn HC, Fatouros PP, Chalfant CE, Shultz MD. Metallofullerene-nanoplatform-delivered interstitial brachytherapy improved survival in a murine model of glioblastoma multiforme. Bioconjugate Chemistry. 23: 1873-80. PMID 22881865 DOI: 10.1021/bc300206q  0.6
2012 Shultz JC, Vu N, Shultz MD, Mba MUU, Shapiro BA, Chalfant CE. The proto-oncogene PKCι regulates the alternative splicing of Bcl-x Pre-mRNA Molecular Cancer Research. 10: 660-669. PMID 22522453 DOI: 10.1158/1541-7786.MCR-11-0363  0.6
2012 Fredenhagen A, Kittelmann M, Oberer L, Kuhn A, Kühnöl J, Délémonté T, Aichholz R, Wang P, Atadja P, Shultz MD. Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589) Drug Metabolism and Disposition. 40: 1041-1050. PMID 22344701 DOI: 10.1124/dmd.111.043620  0.6
2012 Kirby CA, Cheung A, Fazal A, Shultz MD, Stams T. Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939 Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68: 115-118. PMID 22297980 DOI: 10.1107/S1744309111051219  0.6
2012 Shultz MD, Kirby CA, Stams T, Chin DN, Blank J, Charlat O, Cheng H, Cheung A, Cong F, Feng Y, Fortin PD, Hood T, Tyagi V, Xu M, Zhang B, et al. [1,2,4]Triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: Antagonists of the wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding Journal of Medicinal Chemistry. 55: 1127-1136. PMID 22260203 DOI: 10.1021/jm2011222  0.6
2011 Tommasi RA, Weiler S, Mcquire LW, Rogel O, Chambers M, Clark K, Doughty J, Fang J, Ganu V, Grob J, Goldberg R, Goldstein R, Lavoie S, Kulathila R, Macchia W, ... ... Shultz M, et al. Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13 Bioorganic and Medicinal Chemistry Letters. 21: 6440-6445. PMID 21937229 DOI: 10.1016/j.bmcl.2011.08.087  0.6
2011 Shultz MD, Wilson JD, Fuller CE, Zhang J, Dorn HC, Fatouros PP. Metallofullerene-based nanoplatform for brain tumor brachytherapy and longitudinal imaging in a murine orthotopic xenograft model. Radiology. 261: 136-43. PMID 21813738 DOI: 10.1148/radiol.11102569  0.6
2011 Shultz M, Fan J, Chen C, Cho YS, Davis N, Bickford S, Buteau K, Cao X, Holmqvist M, Hsu M, Jiang L, Liu G, Lu Q, Patel C, Suresh JR, et al. The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 4909-12. PMID 21742496 DOI: 10.1016/j.bmcl.2011.06.015  0.6
2011 Whitehead L, Dobler MR, Radetich B, Zhu Y, Atadja PW, Claiborne T, Grob JE, McRiner A, Pancost MR, Patnaik A, Shao W, Shultz M, Tichkule R, Tommasi RA, Vash B, et al. Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors Bioorganic and Medicinal Chemistry. 19: 4626-4634. PMID 21723733 DOI: 10.1016/j.bmc.2011.06.030  0.6
2011 Shultz MD, Cao X, Chen CH, Cho YS, Davis NR, Eckman J, Fan J, Fekete A, Firestone B, Flynn J, Green J, Growney JD, Holmqvist M, Hsu M, Jansson D, et al. Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors. Journal of Medicinal Chemistry. 54: 4752-72. PMID 21650221 DOI: 10.1021/jm200388e  0.6
2011 Fillmore HL, Shultz MD, Henderson SC, Cooper P, Broaddus WC, Chen ZJ, Shu CY, Zhang J, Ge J, Dorn HC, Corwin F, Hirsch JI, Wilson J, Fatouros PP. Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors. Nanomedicine (London, England). 6: 449-58. PMID 21542684 DOI: 10.2217/nnm.10.134  0.6
2011 Carroll KJ, Reveles JU, Shultz MD, Khanna SN, Carpenter EE. Preparation of elemental Cu and Ni nanoparticles by the polyol method: An experimental and theoretical approach Journal of Physical Chemistry C. 115: 2656-2664. DOI: 10.1021/jp1104196  0.6
2010 Zhang J, Ge J, Shultz MD, Chung E, Singh G, Shu C, Fatouros PP, Henderson SC, Corwin FD, Geohegan DB, Puretzky AA, Rouleau CM, More K, Rylander C, Rylander MN, et al. In vitro and in vivo studies of single-walled carbon nanohorns with encapsulated metallofullerenes and exohedrally functionalized quantum dots. Nano Letters. 10: 2843-8. PMID 20698597 DOI: 10.1021/nl1008635  0.6
2010 Shultz MD, Duchamp JC, Wilson JD, Shu CY, Ge J, Zhang J, Gibson HW, Fillmore HL, Hirsch JI, Dorn HC, Fatouros PP. Encapsulation of a radiolabeled cluster inside a fullerene cage, (177)Lu(x)Lu((3-x))N@C(80): an interleukin-13-conjugated radiolabeled metallofullerene platform. Journal of the American Chemical Society. 132: 4980-1. PMID 20307100 DOI: 10.1021/ja9093617  0.6
2010 Cho YS, Whitehead L, Li J, Chen CHT, Jiang L, Vögtle M, Francotte E, Richert P, Wagner T, Traebert M, Lu Q, Cao X, Dumotier B, Fejzo J, Rajan S, ... ... Shultz M, et al. Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824) Journal of Medicinal Chemistry. 53: 2952-2963. PMID 20205394 DOI: 10.1021/jm100007m  0.6
2010 Carroll KJ, Shultz MD, Fatouros PP, Carpenter EE. High magnetization aqueous ferrofluid: A simple one-pot synthesis Journal of Applied Physics. 107. DOI: 10.1063/1.3357342  0.6
2010 Calvin S, Shultz MD, Glowzenski L, Carpenter EE. Annealing temperature and initial iron valence ratio effects on the structural characteristics of nanoscale nickel zinc ferrite Journal of Applied Physics. 107. DOI: 10.1063/1.3269706  0.6
2009 Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, ... ... Shultz M, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature. 461: 614-20. PMID 19759537 DOI: 10.1038/nature08356  0.6
2009 Shultz MD, Marin JR, Naik SH, Wilkins J, Laza JM, Vilas JL, Rodriguez M, Perez N, Carpenter EE. Poly(styrene-co-vinylbenzylchloride-co-divinylbenzene) coated iron oxide: Synthesis and effects on size and morphology Journal of Applied Physics. 105. DOI: 10.1063/1.3077222  0.6
2009 Shultz MD, Braxton W, Taylor C, Carpenter EE. One parameter control of the size of iron oxide nanoparticles synthesized in reverse micelles Journal of Applied Physics. 105. DOI: 10.1063/1.3075983  0.6
2009 Shultz MD, Calvin S, Fernando Gonzalez-Jimenez, Mujica V, Alleluia BC, Carpenter EE. Gold-coated cementite nanoparticles: An oxidation-resistant alternative to α-Iron Chemistry of Materials. 21: 5594-5600. DOI: 10.1021/cm901708v  0.6
2007 Shultz MD, Ulises Reveles J, Khanna SN, Carpenter EE. Reactive nature of dopamine as a surface functionalization agent in iron oxide nanoparticles Journal of the American Chemical Society. 129: 2482-2487. PMID 17290990 DOI: 10.1021/ja0651963  0.6
2007 Shultz MD, Allsbrook MJ, Carpenter EE. Control of the cation occupancies of MnZn ferrite synthesized via reverse micelles Journal of Applied Physics. 101. DOI: 10.1063/1.2713694  0.6
2007 Chinnasamy CN, Yang A, Yoon SD, Hsu K, Shultz MD, Carpenter EE, Mukerjee S, Vittoria C, Harris VG. Size dependent magnetic properties and cation inversion in chemically synthesized Mn Fe2 O4 nanoparticles Journal of Applied Physics. 101. DOI: 10.1063/1.2710218  0.6
2007 Shultz MD, Calvin S, Fatouros PP, Morrison SA, Carpenter EE. Enhanced ferrite nanoparticles as MRI contrast agents Journal of Magnetism and Magnetic Materials. 311: 464-468. DOI: 10.1016/j.jmmm.2006.10.1188  0.6
2006 Shultz MD, Carpenter EE, Morrison SA, Calvin S. Cation occupancy determination in manganese zinc ferrites using Fourier transform infrared spectroscopy Journal of Applied Physics. 99. DOI: 10.1063/1.2151831  0.6
2004 Shultz MD, Ham YW, Lee SG, Davis DA, Brown C, Chmielewski J. Small-molecule dimerization inhibitors of wild-type and mutant HIV protease: a focused library approach. Journal of the American Chemical Society. 126: 9886-7. PMID 15303839 DOI: 10.1021/ja048139n  0.6
2003 Zhao L, O'Reilly MK, Shultz MD, Chmielewski J. Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization Bioorganic and Medicinal Chemistry Letters. 13: 1175-1177. PMID 12643937 DOI: 10.1016/S0960-894X(03)00040-4  0.6
1999 Shultz MD, Chmielewski J. Probing the role of interfacial residues in a dimerization inhibitor of HIV-1 protease Bioorganic and Medicinal Chemistry Letters. 9: 2431-2436. PMID 10476882 DOI: 10.1016/S0960-894X(99)00400-X  0.6
1997 Zutshi R, Franciskovich J, Shultz M, Schweitzer B, Bishop P, Wilson M, Chmielewski J. Targeting the dimerization interface of HIV-1 protease: Inhibition with cross-linked interfacial peptides Journal of the American Chemical Society. 119: 4841-4845. DOI: 10.1021/ja962496j  0.6
1997 Shultz MD, Chmielewski J. Hydrophobicity versus activity in crosslinked interfacial peptide inhibitors of HIV-1 protease Tetrahedron Asymmetry. 8: 3881-3886. DOI: 10.1016/S0957-4166(97)00572-7  0.6
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