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Year Citation  Score
2019 Chen J, Zhang X, Schaller S, Jardetzky TS, Longnecker R. Ephrin Receptor A4 is a New Kaposi's Sarcoma-Associated Herpesvirus Virus Entry Receptor. Mbio. 10. PMID 30782663 DOI: 10.1128/mBio.02892-18  0.76
2018 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Pillars Article: Three-Dimensional Structure of a Human Class II Histocompatibility Molecule Complexed with Superantigen. . 1994. 368: 711-718. Journal of Immunology (Baltimore, Md. : 1950). 201: 1819-1826. PMID 30224361  0.36
2018 Chen J, Sathiyamoorthy K, Zhang X, Schaller S, Perez White BE, Jardetzky TS, Longnecker R. Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus. Nature Microbiology. PMID 29292384 DOI: 10.1038/s41564-017-0081-7  0.76
2017 Wong JJW, Young TA, Zhang J, Liu S, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS. Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. Nature Communications. 8: 781. PMID 28974687 DOI: 10.1038/s41467-017-00863-3  0.4
2017 Möhl BS, Chen J, Park SJ, Jardetzky TS, Longnecker R. Epstein-Barr virus fusion with epithelial cells triggered by gB is restricted by a gL glycosylation site. Journal of Virology. PMID 28956769 DOI: 10.1128/JVI.01255-17  0.76
2017 Sathiyamoorthy K, Jiang J, Möhl BS, Chen J, Zhou ZH, Longnecker R, Jardetzky TS. Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 28939750 DOI: 10.1073/pnas.1704661114  0.76
2017 Sathiyamoorthy K, Chen J, Longnecker R, Jardetzky TS. The COMPLEXity in herpesvirus entry. Current Opinion in Virology. 24: 97-104. PMID 28538165 DOI: 10.1016/j.coviro.2017.04.006  0.76
2017 Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Nature Microbiology. 2: 16272. PMID 28134915 DOI: 10.1038/nmicrobiol.2016.272  0.4
2016 Chen J, Jardetzky TS, Longnecker R. The Cytoplasmic Tail Domain of Epstein-Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment. Mbio. 7. PMID 27935841 DOI: 10.1128/mBio.01871-16  0.76
2016 Sathiyamoorthy K, Hu YX, Möhl BS, Chen J, Longnecker R, Jardetzky TS. Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins. Nature Communications. 7: 13557. PMID 27929061 DOI: 10.1038/ncomms13557  0.76
2016 Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA. Flexibility of the head-stalk linker domain of paramyxovirus HN glycoprotein is essential for triggering virus fusion. Journal of Virology. PMID 27489276 DOI: 10.1128/JVI.01187-16  0.4
2016 Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA. Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane Proximal Stalk Region Influences Stability, Receptor Binding and Neuraminidase Activity. Journal of Virology. PMID 27334593 DOI: 10.1128/JVI.00896-16  0.4
2016 Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE, Jardetzky TS. A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV. Plos One. 11: e0155917. PMID 27224013 DOI: 10.1371/journal.pone.0155917  0.4
2016 Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS. Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nature Communications. 7: 11610. PMID 27194387 DOI: 10.1038/ncomms11610  0.88
2016 Möhl BS, Chen J, Sathiyamoorthy K, Jardetzky TS, Longnecker R. Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus. Molecules and Cells. PMID 27094060 DOI: 10.14348/molcells.2016.0066  0.76
2015 Wong JJ, Paterson RG, Lamb RA, Jardetzky TS. Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712026 DOI: 10.1073/pnas.1523303113  0.88
2015 Möhl BS, Schröter C, Klupp BG, Fuchs W, Mettenleiter TC, Jardetzky TS, Longnecker R. Comparative mutagenesis of Pseudorabies and Epstein-Barr virus gH identifies a structural determinant within domain III of gH required for surface expression and entry function. Journal of Virology. PMID 26656711 DOI: 10.1128/JVI.03032-15  0.76
2015 Bose S, Jardetzky TS, Lamb RA. Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry. Virology. 479: 518-31. PMID 25771804 DOI: 10.1016/j.virol.2015.02.037  0.88
2015 Poor TA, Song AS, Welch BD, Kors CA, Jardetzky TS, Lamb RA. On the stability of parainfluenza virus 5 F proteins. Journal of Virology. 89: 3438-41. PMID 25589638 DOI: 10.1128/JVI.03221-14  0.88
2015 Rowe CL, Chen J, Jardetzky TS, Longnecker R. Membrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers. Mbio. 6. PMID 25564465 DOI: 10.1128/mBio.02285-14  0.76
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. Journal of Immunology (Baltimore, Md. : 1950). 194: 5-11. PMID 25527791  0.36
2015 Rowe CL, Chen J, Jardetzky TS, Longnecker R. Membrane anchoring of epstein-barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers Mbio. 6. DOI: 10.1128/mBio.02285-14  0.88
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 Journal of Immunology. 194: 5-11.  0.88
2014 Möhl BS, Sathiyamoorthy K, Jardetzky TS, Longnecker R. The conserved disulfide bond within domain II of Epstein-Barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells. Journal of Virology. 88: 13570-9. PMID 25231307 DOI: 10.1128/JVI.02272-14  0.76
2014 Sathiyamoorthy K, Jiang J, Hu YX, Rowe CL, Möhl BS, Chen J, Jiang W, Mellins ED, Longnecker R, Zhou ZH, Jardetzky TS. Assembly and architecture of the EBV B cell entry triggering complex. Plos Pathogens. 10: e1004309. PMID 25144748 DOI: 10.1371/journal.ppat.1004309  0.88
2014 Welch BD, Paduch M, Leser GP, Bergman Z, Kors CA, Paterson RG, Jardetzky TS, Kossiakoff AA, Lamb RA. Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies. Journal of Virology. 88: 11713-25. PMID 25122782 DOI: 10.1128/JVI.01707-14  0.88
2014 Chen J, Zhang X, Jardetzky TS, Longnecker R. The Epstein-Barr virus (EBV) glycoprotein B cytoplasmic C-terminal tail domain regulates the energy requirement for EBV-induced membrane fusion Journal of Virology. 88: 11686-11695. PMID 25100836 DOI: 10.1128/JVI.01349-14  0.88
2014 Poor TA, Jones LM, Sood A, Leser GP, Plasencia MD, Rempel DL, Jardetzky TS, Woods RJ, Gross ML, Lamb RA. Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting. Proceedings of the National Academy of Sciences of the United States of America. 111: E2596-605. PMID 24927585 DOI: 10.1073/pnas.1408983111  0.88
2014 Eggel A, Baravalle G, Hobi G, Kim B, Buschor P, Forrer P, Shin JS, Vogel M, Stadler BM, Dahinden CA, Jardetzky TS. Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells Journal of Allergy and Clinical Immunology. 133: 1709-1719.e8. PMID 24642143 DOI: 10.1016/j.jaci.2014.02.005  0.88
2014 Jardetzky TS, Lamb RA. Activation of paramyxovirus membrane fusion and virus entry. Current Opinion in Virology. 5: 24-33. PMID 24530984 DOI: 10.1016/j.coviro.2014.01.005  0.88
2014 Bose S, Song AS, Jardetzky TS, Lamb RA. Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells. Journal of Virology. 88: 3925-41. PMID 24453369 DOI: 10.1128/JVI.03741-13  0.88
2014 Möhl BS, Sathiyamoorthy K, Jardetzky TS, Longnecker R. The conserved disulfide bond within domain II of epstein-barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells Journal of Virology. 88: 13570-13579. DOI: 10.1128/JVI.02272-14  0.88
2013 Bose S, Heath CM, Shah PA, Alayyoubi M, Jardetzky TS, Lamb RA. Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. Journal of Virology. 87: 13520-31. PMID 24089572 DOI: 10.1128/JVI.02123-13  0.88
2013 Welch BD, Yuan P, Bose S, Kors CA, Lamb RA, Jardetzky TS. Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain. Plos Pathogens. 9: e1003534. PMID 23950713 DOI: 10.1371/journal.ppat.1003534  0.88
2013 Park M, Wetzler M, Jardetzky TS, Barron AE. A Readily Applicable Strategy to Convert Peptides to Peptoid-based Therapeutics Plos One. 8. PMID 23555603 DOI: 10.1371/journal.pone.0058874  0.88
2013 Chen J, Jardetzky TS, Longneckera R. The large groove found in the gH/gL structure is an important functional domain for epstein-barr virus fusion Journal of Virology. 87: 3620-3627. PMID 23325693 DOI: 10.1128/JVI.03245-12  0.88
2013 Rowe CL, Connolly SA, Chen J, Jardetzky TS, Longnecker R. A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion Virology. 436: 118-126. PMID 23200314 DOI: 10.1016/j.virol.2012.10.039  0.88
2012 Kim B, Eggel A, Tarchevskaya SS, Vogel M, Prinz H, Jardetzky TS. Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor Nature. 491: 613-617. PMID 23103871 DOI: 10.1038/nature11546  0.88
2012 Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA. Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 16672-7. PMID 23012473 DOI: 10.1073/pnas.1213802109  0.88
2012 Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions Analytical Biochemistry. 431: 84-89. PMID 22995065 DOI: 10.1016/j.ab.2012.09.010  0.88
2012 Zokarkar A, Connolly SA, Jardetzky TS, Lamb RA. Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external region. Journal of Virology. 86: 12397-401. PMID 22951841 DOI: 10.1128/JVI.02006-12  0.88
2012 Bose S, Zokarkar A, Welch BD, Leser GP, Jardetzky TS, Lamb RA. Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering. Proceedings of the National Academy of Sciences of the United States of America. 109: E2625-34. PMID 22949640 DOI: 10.1073/pnas.1213813109  0.88
2012 Wurzburg BA, Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation Journal of Biological Chemistry. 287: 36251-36257. PMID 22948141 DOI: 10.1074/jbc.M112.407502  0.88
2012 Yuan P, Paterson RG, Leser GP, Lamb RA, Jardetzky TS. Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence. Plos Pathogens. 8: e1002855. PMID 22912577 DOI: 10.1371/journal.ppat.1002855  0.88
2012 Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE, Jardetzky TS. Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nature Structural & Molecular Biology. 19: 461-3. PMID 22388735 DOI: 10.1038/nsmb.2250  0.88
2012 Zhu J, Lin SJ, Zou C, Makanji Y, Jardetzky TS, Woodruff TK. Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling Journal of Biological Chemistry. 287: 8060-8070. PMID 22267736 DOI: 10.1074/jbc.M111.293381  0.88
2012 Chen J, Rowe CL, Jardetzky TS, Longnecker R. The KGD motif of Epstein-Barr virus gH/gL is bifunctional, orchestrating infection of B cells and epithelial cells. Mbio. 3. PMID 22215569 DOI: 10.1128/mBio.00290-11  0.88
2011 Park M, Jardetzky TS, Barron AE. NMEGylation: a novel modification to enhance the bioavailability of therapeutic peptides. Biopolymers. 96: 688-693. PMID 22180913  0.88
2011 Bose S, Welch BD, Kors CA, Yuan P, Jardetzky TS, Lamb RA. Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. Journal of Virology. 85: 12855-66. PMID 21994464 DOI: 10.1128/JVI.06350-11  0.88
2011 Yuan P, Swanson KA, Leser GP, Paterson RG, Lamb RA, Jardetzky TS. Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk. Proceedings of the National Academy of Sciences of the United States of America. 108: 14920-5. PMID 21873198 DOI: 10.1073/pnas.1111691108  0.88
2011 Rowe CL, Matsuura H, Jardetzky TS, Longnecker R. Investigation of the function of the putative self-association site of Epstein-Barr virus (EBV) glycoprotein 42 (gp42) Virology. 415: 122-131. PMID 21550622 DOI: 10.1016/j.virol.2011.04.003  0.88
2011 Backovic M, Jardetzky TS. Class III viral membrane fusion proteins Advances in Experimental Medicine and Biology. 950: 91-101. PMID 21506008 DOI: 10.1007/978-94-007-0782-5_3  0.88
2011 Connolly SA, Jackson JO, Jardetzky TS, Longnecker R. Fusing structure and function: A structural view of the herpesvirus entry machinery Nature Reviews Microbiology. 9: 369-381. PMID 21478902 DOI: 10.1038/nrmicro2548  0.88
2011 Lin SJ, Hu YX, Zhu J, Woodruff TK, Jardetzky TS. Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-β binding Proceedings of the National Academy of Sciences of the United States of America. 108: 5232-5236. PMID 21402931 DOI: 10.1073/pnas.1010689108  0.88
2011 Plate AE, Reimer JJ, Jardetzky TS, Longnecker R. Mapping regions of Epstein-Barr virus (EBV) glycoprotein B (gB) important for fusion function with gH/gL. Virology. 413: 26-38. PMID 21376360 DOI: 10.1016/j.virol.2010.12.006  0.88
2011 Park M, Matsuura H, Lamb RA, Barron AE, Jardetzky TS. A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform. Analytical Biochemistry. 409: 195-201. PMID 20971054 DOI: 10.1016/j.ab.2010.10.020  0.88
2010 Matsuura H, Kirschner AN, Longnecker R, Jardetzky TS. Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex Proceedings of the National Academy of Sciences of the United States of America. 107: 22641-22646. PMID 21149717 DOI: 10.1073/pnas.1011806108  0.88
2010 Liu F, Marquardt G, Kirschner AN, Longnecker R, Jardetzky TS. Mapping the N-terminal residues of Epstein-Barr virus gp42 that bind gH/gL by using fluorescence polarization and cell-based fusion assays Journal of Virology. 84: 10375-10385. PMID 20668073 DOI: 10.1128/JVI.00381-10  0.88
2010 Swanson K, Wen X, Leser GP, Paterson RG, Lamb RA, Jardetzky TS. Structure of the Newcastle disease virus F protein in the post-fusion conformation. Virology. 402: 372-9. PMID 20439109 DOI: 10.1016/j.virol.2010.03.050  0.88
2010 Zhu J, Braun EL, Kohno S, Antenos M, Xu EY, Cook RW, Lin SJ, Moore BC, Guillette LJ, Jardetzky TS, Woodruff TK. Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist. Plos One. 5: e9457. PMID 20209104 DOI: 10.1371/journal.pone.0009457  0.88
2010 Shaw PL, Kirschner AN, Jardetzky TS, Longnecker R. Characteristics of Epstein-Barr virus envelope protein gp42 Virus Genes. 40: 307-319. PMID 20162447 DOI: 10.1007/s11262-010-0455-x  0.88
2009 Connolly SA, Leser GP, Jardetzky TS, Lamb RA. Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering. Journal of Virology. 83: 10857-68. PMID 19710150 DOI: 10.1128/JVI.01191-09  0.88
2009 Wurzburg BA, Jardetzky TS. Conformational Flexibility in Immunoglobulin E-Fc3-4 Revealed in Multiple Crystal Forms Journal of Molecular Biology. 393: 176-190. PMID 19682998 DOI: 10.1016/j.jmb.2009.08.012  0.88
2009 Plate AE, Smajlovi? J, Jardetzky TS, Longnecker R. Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion Journal of Virology. 83: 7678-7689. PMID 19457993 DOI: 10.1128/JVI.00457-09  0.88
2009 Sorem J, Jardetzky TS, Longnecker R. Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes Journal of Virology. 83: 6664-6672. PMID 19369343 DOI: 10.1128/JVI.00195-09  0.88
2009 Backovic M, Jardetzky TS. Class III viral membrane fusion proteins. Current Opinion in Structural Biology. 19: 189-96. PMID 19356922 DOI: 10.1016/j.sbi.2009.02.012  0.88
2009 Murthy SNP, Lukas TJ, Jardetzky TS, Lorand L. Selectivity in the post-translational, transglutaminase-dependent acylation of lysine residues Biochemistry. 48: 2654-2660. PMID 19222223 DOI: 10.1021/bi802323z  0.88
2009 Kirschner AN, Sorem J, Longnecker R, Jardetzky TS. Structure of Epstein-Barr Virus Glycoprotein 42 Suggests a Mechanism for Triggering Receptor-Activated Virus Entry Structure. 17: 223-233. PMID 19217393 DOI: 10.1016/j.str.2008.12.010  0.88
2009 Backovic M, Longnecker R, Jardetzky TS. Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B Proceedings of the National Academy of Sciences of the United States of America. 106: 2880-2885. PMID 19196955 DOI: 10.1073/pnas.0810530106  0.88
2009 Bissonnette ML, Donald JE, DeGrado WF, Jardetzky TS, Lamb RA. Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. Journal of Molecular Biology. 386: 14-36. PMID 19121325 DOI: 10.1016/j.jmb.2008.12.029  0.88
2009 Reimer JJ, Backovic M, Deshpande CG, Jardetzky T, Longnecker R. Analysis of Epstein-Barr virus glycoprotein B functional domains via linker insertion mutagenesis. Journal of Virology. 83: 734-47. PMID 18987135 DOI: 10.1128/JVI.01817-08  0.88
2009 Longnecker R, Hutt-Fletcher L, Jardetzky T. Epstein-Barr Virus entry Dna Tumor Viruses. 355-378. DOI: 10.1007/978-0-387-68945-6_15  0.88
2008 Jing X, Ma C, Ohigashi Y, Oliveira FA, Jardetzky TS, Pinto LH, Lamb RA. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proceedings of the National Academy of Sciences of the United States of America. 105: 10967-72. PMID 18669647 DOI: 10.1073/pnas.0804958105  0.88
2008 Yuan P, Leser GP, Demeler B, Lamb RA, Jardetzky TS. Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein. Virology. 378: 282-91. PMID 18597807 DOI: 10.1016/j.virol.2008.05.023  0.88
2008 Neuhaus F, Widom J, MacDonald R, Jardetzky T, Radhakrishnan I. Program review: Challenges and opportunities for training the next generation of biophysicists: Perspectives of the directors of the Molecular Biophysics Training Program at Northwestern University Biopolymers. 89: 253-255. PMID 18293401 DOI: 10.1002/bip.20929  0.88
2007 Lamb RA, Jardetzky TS. Structural basis of viral invasion: lessons from paramyxovirus F. Current Opinion in Structural Biology. 17: 427-36. PMID 17870467 DOI: 10.1016/j.sbi.2007.08.016  0.88
2007 Backovic M, Leser GP, Lamb RA, Longnecker R, Jardetzky TS. Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. Virology. 368: 102-13. PMID 17655906 DOI: 10.1016/j.virol.2007.06.031  0.88
2007 Kirschner AN, Lowrey AS, Longnecker R, Jardetzky TS. Binding-site interactions between epstein-barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion Journal of Virology. 81: 9216-9229. PMID 17581996 DOI: 10.1128/JVI.00575-07  0.88
2007 Backovic M, Jardetzky TS, Longnecker R. Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity Journal of Virology. 81: 9596-9600. PMID 17553877 DOI: 10.1128/JVI.00758-07  0.88
2007 Lerch TF, Shimasaki S, Woodruff TK, Jardetzky TS. Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions Journal of Biological Chemistry. 282: 15930-15939. PMID 17409095 DOI: 10.1074/jbc.M700737200  0.88
2007 Lerch TF, Xu M, Jardetzky TS, Mayo KE, Radhakrishnan I, Kazer R, Shea LD, Woodruff TK. The structures that underlie normal reproductive function Molecular and Cellular Endocrinology. 267: 1-5. PMID 17140726 DOI: 10.1016/j.mce.2006.10.018  0.88
2006 Connolly SA, Leser GP, Yin HS, Jardetzky TS, Lamb RA. Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 103: 17903-8. PMID 17093041 DOI: 10.1073/pnas.0608678103  0.88
2006 Kirschner AN, Omerovi? J, Popov B, Longnecker R, Jardetzky TS. Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion Journal of Virology. 80: 9444-9454. PMID 16973550 DOI: 10.1128/JVI.00572-06  0.88
2006 Lin SJ, Lerch TF, Cook RW, Jardetzky TS, Woodruff TK. The structural basis of TGF-β, bone morphogenetic protein, and activin ligand binding Reproduction. 132: 179-190. PMID 16885528 DOI: 10.1530/rep.10.1072  0.88
2006 Wurzburg BA, Tarchevskaya SS, Jardetzky TS. Structural Changes in the Lectin Domain of CD23, the Low-Affinity IgE Receptor, upon Calcium Binding Structure. 14: 1049-1058. PMID 16765898 DOI: 10.1016/j.str.2006.03.017  0.88
2006 Yin HS, Wen X, Paterson RG, Lamb RA, Jardetzky TS. Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation. Nature. 439: 38-44. PMID 16397490 DOI: 10.1038/nature04322  0.88
2006 Lamb RA, Paterson RG, Jardetzky TS. Paramyxovirus membrane fusion: lessons from the F and HN atomic structures. Virology. 344: 30-7. PMID 16364733 DOI: 10.1016/j.virol.2005.09.007  0.88
2005 Thompson TB, Lerch TF, Cook RW, Woodruff TK, Jardetzky TS. The structure of the follistatin: Activin complex reveals antagonism of both type I and type II receptor binding Developmental Cell. 9: 535-543. PMID 16198295 DOI: 10.1016/j.devcel.2005.09.008  0.88
2005 Cook RW, Thompson TB, Kurup SP, Jardetzky TS, Woodruff TK. Structural basis for a functional antagonist in the transforming growth factor beta superfamily. The Journal of Biological Chemistry. 280: 40177-86. PMID 16186117 DOI: 10.1074/jbc.M504591200  0.56
2005 Yin HS, Paterson RG, Wen X, Lamb RA, Jardetzky TS. Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 9288-93. PMID 15964978 DOI: 10.1073/pnas.0503989102  0.88
2005 Yuan P, Thompson TB, Wurzburg BA, Paterson RG, Lamb RA, Jardetzky TS. Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose. Structure (London, England : 1993). 13: 803-15. PMID 15893670 DOI: 10.1016/j.str.2005.02.019  0.88
2005 Cook RW, Thompson TB, Kurup SP, Jardetzky TS, Woodruff TK. Structural basis for a functional antagonist in the transforming growth factor β superfamily Journal of Biological Chemistry. 280: 40177-40186. DOI: 10.1074/jbc.M504591200  0.88
2004 Russell CJ, Jardetzky TS, Lamb RA. Conserved glycine residues in the fusion peptide of the paramyxovirus fusion protein regulate activation of the native state. Journal of Virology. 78: 13727-42. PMID 15564482 DOI: 10.1128/JVI.78.24.13727-13742.2004  0.88
2004 Thompson TB, Cook RW, Chapman SC, Jardetzky TS, Woodruff TK. Beta A versus beta B: Is it merely a matter of expression? Molecular and Cellular Endocrinology. 225: 9-17. PMID 15451562 DOI: 10.1016/j.mce.2004.02.007  0.88
2004 Cook RW, Thompson TB, Jardetzky TS, Woodruff TK. Molecular biology of inhibin action Seminars in Reproductive Medicine. 22: 269-276. PMID 15319829 DOI: 10.1055/s-2004-831902  0.88
2004 Waning DL, Russell CJ, Jardetzky TS, Lamb RA. Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail. Proceedings of the National Academy of Sciences of the United States of America. 101: 9217-22. PMID 15197264 DOI: 10.1073/pnas.0403339101  0.88
2004 Silva AL, Omerovi? J, Jardetzky TS, Longnecker R. Mutational analyses of Epstein-Barr virus glycoprotein 42 reveal functional domains not involved in receptor binding but required for membrane fusion Journal of Virology. 78: 5946-5956. PMID 15140992 DOI: 10.1128/JVI.78.11.5946-5956.2004  0.88
2004 Jardetzky TS, Lamb RA. Virology: a class act. Nature. 427: 307-8. PMID 14737155 DOI: 10.1038/427307a  0.88
2003 Russell CJ, Kantor KL, Jardetzky TS, Lamb RA. A dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion. The Journal of Cell Biology. 163: 363-74. PMID 14581458 DOI: 10.1083/jcb.200305130  0.88
2003 Ressing ME, Van Leeuwen D, Verreck FAW, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff THM, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJHJ. Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition Proceedings of the National Academy of Sciences of the United States of America. 100: 11583-11588. PMID 14504389 DOI: 10.1073/pnas.2034960100  0.88
2003 Wurzburg BA, Jardetzky TS. The IgA receptor complex: A two-for-one deal Nature Structural Biology. 10: 585-587. PMID 12886289 DOI: 10.1038/nsb0803-585  0.88
2003 McShane MP, Mullen MM, Haan KM, Jardetzky TS, Longnecker R. Mutational analysis of the HLA class II interaction with Epstein-Barr virus glycoprotein 42 Journal of Virology. 77: 7655-7662. PMID 12805465 DOI: 10.1128/JVI.77.13.7655-7662.2003  0.88
2003 Thompson TB, Woodruff TK, Jardetzky TS. Structures of an ActRIIB:activin a complex reveal a novel binding mode for TGF-β ligand:receptor interactions Embo Journal. 22: 1555-1566. PMID 12660162 DOI: 10.1093/emboj/cdg156  0.88
2002 Jardetzky T. HIV: Conformational camouflage Nature. 420: 623-624. PMID 12478278 DOI: 10.1038/420623a  0.88
2002 Wurzburg BA, Jardetzky TS. Structural insights into the interactions between human IgE and its high affinity receptor FcεRI Molecular Immunology. 38: 1063-1072. PMID 11955598 DOI: 10.1016/S0161-5890(02)00035-4  0.88
2002 Mullen MM, Haan KM, Longnecker R, Jardetzky TS. Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1 Molecular Cell. 9: 375-385. PMID 11864610 DOI: 10.1016/S1097-2765(02)00465-3  0.88
2001 Garman SC, Sechi S, Kinet JP, Jardetzky TS. The analysis of the human high affinity IgE receptor FcεRIα from multiple crystal forms Journal of Molecular Biology. 311: 1049-1062. PMID 11531339 DOI: 10.1006/jmbi.2001.4929  0.88
2001 Russell CJ, Jardetzky TS, Lamb RA. Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion. The Embo Journal. 20: 4024-34. PMID 11483506 DOI: 10.1093/emboj/20.15.4024  0.88
2000 Dutch RE, Jardetzky TS, Lamb RA. Virus membrane fusion proteins: biological machines that undergo a metamorphosis. Bioscience Reports. 20: 597-612. PMID 11426696 DOI: 10.1023/A:1010467106305  0.88
2000 Wurzburg BA, Garman SC, Jardetzky TS. Structure of the human IgE-Fc Cε3-Cε4 reveals conformational flexibility in the antibody effector domains Immunity. 13: 375-385. PMID 11021535  0.88
2000 Garman SC, Wurzburg BA, Tarchevskaya SS, Klnet JP, Jardetzky TS. Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα Nature. 406: 259-266. PMID 10917520 DOI: 10.1038/35018500  0.88
1999 Garman SC, Kinet JP, Jardetzky TS. The crystal structure of the human high-affinity IgE receptor (FcεRIα) Annual Review of Immunology. 17: 973-976. PMID 10358779 DOI: 10.1146/annurev.immunol.17.1.973  0.88
1999 Baker KA, Dutch RE, Lamb RA, Jardetzky TS. Structural basis for paramyxovirus-mediated membrane fusion. Molecular Cell. 3: 309-19. PMID 10198633 DOI: 10.1016/S1097-2765(00)80458-X  0.88
1999 Sundberg E, Jardetzky TS. Structural basis for HLA-DQ binding by the streptococcal superantigen SSA Nature Structural Biology. 6: 123-129. PMID 10048922 DOI: 10.1038/5809  0.88
1998 Garman SC, Kinet JP, Jardetzky TS. Crystal structure of the human high-affinity IgE receptor Cell. 95: 951-961. PMID 9875849 DOI: 10.1016/S0092-8674(00)81719-5  0.88
1998 Ceman S, Wu S, Jardetzky TS, Sant AJ. Alteration of a single hydrogen bond between class II molecules and peptide results in rapid degradation of class ii molecules after invariant chain removal Journal of Experimental Medicine. 188: 2139-2149. PMID 9841927 DOI: 10.1084/jem.188.11.2139  0.88
1997 Jardetzky T. Not just another Fab: The crystal structure of a TcR-MHC-peptide complex Structure. 5: 159-163. PMID 9032079  0.88
1996 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides. Proceedings of the National Academy of Sciences of the United States of America. 93: 734-8. PMID 8570625 DOI: 10.1073/pnas.93.2.734  0.88
1995 Brown JH, Jardetzky TS, Stern LJ, Gorga JC, Strominger JL, Wiley DC. Human class II MHC molecule HLA-DR1: X-ray structure determined from three crystal forms. Acta Crystallographica. Section D, Biological Crystallography. 51: 946-61. PMID 15299764 DOI: 10.1107/S0907444995002289  0.88
1995 Schafer PH, Pierce SK, Jardetzky TS. The structure of MHC class II: A role for dimer of dimers Seminars in Immunology. 7: 389-398. PMID 8775464  0.88
1994 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature. 368: 711-8. PMID 8152483 DOI: 10.1038/368711a0  0.88
1994 Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368: 215-21. PMID 8145819 DOI: 10.1038/368215a0  0.88
1994 Thibodeau J, Cloutier I, Lavoie PM, Labrecque N, Mourad W, Jardetzky T, Sékaly RP. Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding Science. 266: 1874-1878. PMID 7997881  0.88
1993 Guo HC, Madden DR, Silver ML, Jardetzky TS, Gorga JC, Strominger JL, Wiley DC. Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705. Proceedings of the National Academy of Sciences of the United States of America. 90: 8053-7. PMID 8367462  0.88
1993 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364: 33-9. PMID 8316295 DOI: 10.1038/364033a0  0.88
1992 Guo HC, Jardetzky TS, Garrett TP, Lane WS, Strominger JL, Wiley DC. Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature. 360: 364-6. PMID 1448153 DOI: 10.1038/360364a0  0.88
1991 Jardetzky TS, Lane WS, Robinson RA, Madden DR, Wiley DC. Identification of self peptides bound to purified HLA-B27. Nature. 353: 326-9. PMID 1922338 DOI: 10.1038/353326a0  0.88
1991 Gorga JC, Brown JH, Jardetzky T, Wiley DC, Strominger JL. Crystallization of HLA-DR antigens. Research in Immunology. 142: 401-7. PMID 1754711 DOI: 10.1016/0923-2494(91)90038-K  0.88
1991 Kilgus J, Jardetzky T, Gorga JC, Trzeciak A, Gillessen D, Sinigaglia F. Analysis of the permissive association of a malaria T cell epitope with DR molecules. Journal of Immunology (Baltimore, Md. : 1950). 146: 307-15. PMID 1701796  0.88
1990 Jardetzky TS, Gorga JC, Busch R, Rothbard J, Strominger JL, Wiley DC. Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding. The Embo Journal. 9: 1797-803. PMID 2189723  0.88
1988 Brown JH, Jardetzky T, Saper MA, Samraoui B, Bjorkman PJ, Wiley DC. A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature. 332: 845-50. PMID 3258651 DOI: 10.1038/332845a0  0.88
1988 Jardetzky TS, Seville M. Calculation of rate and equilibrium constants for a ping-pong mechanism from steady-state data Biochemistry. 27: 6758-6763.  0.88
1987 Priestle JP, Grütter MG, White JL, Vincent MG, Kania M, Wilson E, Jardetzky TS, Kirschner K, Jansonius JN. Three-dimensional structure of the bifunctional enzyme N-(5'-phosphoribosyl)anthranilate isomerase-indole-3-glycerol-phosphate synthase from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 84: 5690-4. PMID 3303031  0.88
1987 Kirschner K, Szadkowski H, Jardetzky TS, Hager V. Phosphoribosylanthranilate isomerase-indoleglycerol-phosphate synthase from Escherichia coli. Methods in Enzymology. 142: 386-97. PMID 3298981 DOI: 10.1016/S0076-6879(87)42050-8  0.88
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