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Raymond J. Andersen, Ph.D. - Publications

Affiliations: 
Chemistry and Earth, Ocean and Atmospheric Sciences University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Natural Product Isolation, Elucidation, and Synthesis
Website:
http://www.chem.ubc.ca/our-people/profiles/raymond-j-andersen-0

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 de Oliveira JAM, Williams DE, Andersen RJ, Sarragiotto MH, Baldoqui DC. Mycenolide A, new butenolide from a marine sediment-derived bacterium Streptomyces sp. 4054. Natural Product Research. 1-4. PMID 30964338 DOI: 10.1080/14786419.2019.1597351  0.48
2019 Steinberger J, Robert F, Hallé M, Williams DE, Cencic R, Sawhney N, Pelletier D, Williams P, Igarashi Y, Porco JA, Rodriguez AD, Kopp B, Bachmann B, Andersen RJ, Pelletier J. Tracing MYC Expression for Small Molecule Discovery. Cell Chemical Biology. PMID 30880156 DOI: 10.1016/j.chembiol.2019.02.007  0.48
2019 Gao Z, Ovchinnikova OG, Huang BS, Liu F, Williams DE, Andersen R, Lowary TL, Whitfield C, Withers SG. A High-Throughput "FP-Tag" Assay for the Identification of Glycosyltransferase Inhibitors. Journal of the American Chemical Society. PMID 30698425 DOI: 10.1021/jacs.8b10940  0.48
2019 Mohamad-Ramshan R, Ratnaweera PB, Williams DE, de Silva ED, Andersen RJ. Stable isotope feeding studies reveal a steroid 5(6→7)abeo ring contraction biogenesis for the antibiotic solanioic acid produced by cultures of the fungus Rhizoctonia solani. The Journal of Antibiotics. PMID 30635614 DOI: 10.1038/s41429-018-0137-9  0.48
2018 de Souza RTMP, Freire VF, Gubiani JR, Ferreira RO, Trivella DBB, Moraes FC, Paradas WC, Salgado LT, Pereira RC, Amado Filho GM, Ferreira AG, Williams DE, Andersen RJ, Molinski TF, Berlinck RGS. Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth. Journal of Natural Products. PMID 30281303 DOI: 10.1021/acs.jnatprod.8b00533  0.64
2018 Kuroda Y, Nicacio KJ, da Silva-Jr IA, Leger PR, Chang S, Gubiani JR, Deflon VM, Nagashima N, Rode A, Blackford K, Ferreira AG, Sette LD, Williams DE, Andersen RJ, Jancar S, et al. Isolation, synthesis and bioactivity studies of phomactin terpenoids. Nature Chemistry. PMID 30061613 DOI: 10.1038/s41557-018-0084-x  0.48
2018 Richard K, Williams DE, de Silva ED, Brockman MA, Brumme ZL, Andersen RJ, Tietjen I. Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products. Viruses. 10. PMID 29954099 DOI: 10.3390/v10070348  0.48
2018 Mioka T, Fujimura-Kamada K, Mizugaki N, Kishimoto T, Sano T, Nunome H, Williams DE, Andersen RJ, Tanaka K. Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane. Molecular Biology of the Cell. PMID 29540528 DOI: 10.1091/mbc.E17-04-0217  0.48
2018 Tietjen I, Williams DE, Read S, Kuang XT, Mwimanzi P, Wilhelm E, Markle T, Kinloch NN, Naphen CN, Tenney K, Mesplède T, Wainberg MA, Crews P, Bell B, Andersen RJ, et al. Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A. Antiviral Research. PMID 29476895 DOI: 10.1016/j.antiviral.2018.02.017  0.48
2018 Williams DE, Gunasekara NW, Ratnaweera PB, Zheng Z, Ellis S, Dada S, Patrick BO, Wijesundera RLC, Nanayakkara CM, Jefferies WA, de Silva ED, Andersen RJ. Serpulanines A to C, N-Oxidized Tyrosine Derivatives Isolated from the Sri Lankan Fungus Serpula sp.: Structure Elucidation, Synthesis, and Histone Deacetylase Inhibition. Journal of Natural Products. PMID 29303267 DOI: 10.1021/acs.jnatprod.7b00680  0.48
2017 Tietjen I, Ngwenya BN, Fotso G, Williams DE, Simonambango S, Ngadjui BT, Andersen RJ, Brockman MA, Brumme ZL, Andrae-Marobela K. The Croton megalobotrys Müll Arg. traditional medicine in HIV/AIDS management: Documentation of patient use, in vitro activation of latent HIV-1 provirus, and isolation of active phorbol esters. Journal of Ethnopharmacology. PMID 28970153 DOI: 10.1016/j.jep.2017.09.038  0.48
2017 Wong KM, Williams DE, Centko R, de Silva ED, Andersen RJ. Chemical Transformations of the Fungal Meroterpenoid Dhilirolide A Reveal Skeletal Degradation and Rearrangement Reactions with Biosynthetic Implications. Organic Letters. PMID 28805391 DOI: 10.1021/acs.orglett.7b02037  0.48
2017 Kruglyak N, Williams DE, Chen H, Law S, Kaleta J, Villanueva I, Davies JE, Andersen RJ, Brömme D. Leupeptazin, a highly modified tripeptide isolated from cultures of a Streptomyces sp. inhibits cathepsin K. Bioorganic & Medicinal Chemistry Letters. PMID 28228366 DOI: 10.1016/j.bmcl.2017.02.007  0.48
2017 Nicacio KJ, Ióca LP, Fróes AM, Leomil L, Appolinario LR, Thompson CC, Thompson FL, Ferreira AG, Williams DE, Andersen RJ, Eustaquio AS, Berlinck RG. Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges. Journal of Natural Products. PMID 28191971 DOI: 10.1021/acs.jnatprod.6b00838  0.48
2017 A Ramirez MC, Williams DE, Gubiani JR, Parra LL, Santos MF, Ferreira DD, Mesquita JT, Tempone AG, Ferreira AG, Padula V, Hajdu E, Andersen RJ, Berlinck RG. Rearranged Terpenoids from the Marine Sponge Darwinella cf. oxeata and Its Predator, the Nudibranch Felimida grahami. Journal of Natural Products. PMID 28191951 DOI: 10.1021/acs.jnatprod.6b01160  0.48
2017 Williams DE, Dalisay DS, Chen J, Polishchuck EA, Patrick BO, Narula G, Ko M, Av-Gay Y, Li H, Magarvey N, Andersen RJ. Aminorifamycins and Sporalactams Produced in Culture by a Micromonospora sp. Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics. Organic Letters. PMID 28164711 DOI: 10.1021/acs.orglett.6b03619  0.48
2016 Dissanayake RK, Ratnaweera PB, Williams DE, Wijayarathne CD, Wijesundera RLC, Andersen RJ, de Silva ED. Antimicrobial activities of endophytic fungi of the Sri Lankan aquatic plant and chaetoglobosin A and C, produced by the endophytic fungus . Mycology. 7: 1-8. PMID 30123610 DOI: 10.1080/21501203.2015.1136708  0.48
2016 Wang M, Tietjen I, Chen M, Williams DE, Daoust J, Brockman MA, Andersen RJ. Sesterterpenoids Isolated from the Sponge Phorbas sp. Activate Latent HIV-1 Provirus Expression. The Journal of Organic Chemistry. PMID 27768313 DOI: 10.1021/acs.joc.6b02312  0.48
2016 Banuelos CA, Tavakoli I, Tien AH, Caley DP, Mawji NR, Li Z, Wang J, Yang YC, Imamura Y, Yan L, Wen JG, Andersen RJ, Sadar MD. Sintokamide A is a Novel Antagonist of Androgen Receptor that Uniquely Binds Activation Function-1 in its Amino-Terminal Domain. The Journal of Biological Chemistry. PMID 27576691 DOI: 10.1074/jbc.M116.734475  0.64
2016 Aguda AH, Lavallee V, Cheng P, Bott TM, Meimetis LG, Law S, Nguyen NT, Williams DE, Kaleta J, Villanueva I, Davies J, Andersen RJ, Brayer GD, Brömme D. Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts. Journal of Natural Products. PMID 27498895 DOI: 10.1021/acs.jnatprod.6b00215  0.64
2016 de Castro MV, Ióca LP, Williams DE, Costa BZ, Mizuno CM, Santos MF, de Jesus K, Ferreira ÉL, Seleghim MH, Sette LD, Pereira Filho ER, Ferreira AG, Gonçalves NS, Santos RA, Patrick BO, ... Andersen RJ, et al. Condensation of Macrocyclic Polyketides Produced by Penicillium sp. DRF2 with Mercaptopyruvate Represents a New Fungal Detoxification Pathway. Journal of Natural Products. PMID 27227682 DOI: 10.1021/acs.jnatprod.6b00295  0.64
2016 Williams DE, Izard F, Arnould S, Dalisay DS, Tantapakul C, Maneerat W, Matainaho T, Julien E, Andersen RJ. Structures of Nahuoic Acids B to E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A. The Journal of Organic Chemistry. PMID 26815947 DOI: 10.1021/acs.joc.5b02569  0.64
2016 Dissanayake RK, Ratnaweera PB, Williams DE, Wijayarathne CD, Wijesundera RLC, Andersen RJ, de Silva ED. Antimicrobial activities of mycoleptodiscin B isolated from endophytic fungus Mycoleptodiscus sp. of Calamus thwaitesii Becc Journal of Applied Pharmaceutical Science. 6: 001-006. DOI: 10.7324/JAPS.2016.600101  0.48
2016 Dissanayake RK, Ratnaweera PB, Williams DE, Wijayarathne CD, Wijesundera RLC, Andersen RJ, de Silva ED. Antimicrobial activities of endophytic fungi of the Sri Lankan aquatic plant Nymphaea nouchali and chaetoglobosin A and C, produced by the endophytic fungus Chaetomium globosum Mycology. 1-8. DOI: 10.1080/21501203.2015.1136708  0.64
2015 Williams DE, Bottriell H, Davies J, Tietjen I, Brockman MA, Andersen RJ. Unciaphenol, an Oxygenated Analogue of the Bergman Cyclization Product of Uncialamycin Exhibits Anti-HIV Activity. Organic Letters. 17: 5304-7. PMID 26465962 DOI: 10.1021/acs.orglett.5b02664  0.64
2015 Ferreira EL, Williams DE, Ióca LP, Morais-Urano RP, Santos MF, Patrick BO, Elias LM, Lira SP, Ferreira AG, Passarini MR, Sette LD, Andersen RJ, Berlinck RG. Structure and Biogenesis of Roussoellatide, a Dichlorinated Polyketide from the Marine-Derived Fungus Roussoella sp. DLM33. Organic Letters. 17: 5152-5. PMID 26444492 DOI: 10.1021/acs.orglett.5b02060  0.48
2015 Williams LK, Zhang X, Caner S, Tysoe C, Nguyen NT, Wicki J, Williams DE, Coleman J, McNeill JH, Yuen V, Andersen RJ, Withers SG, Brayer GD. The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif. Nature Chemical Biology. 11: 691-6. PMID 26214255 DOI: 10.1038/nchembio.1865  0.48
2015 Ratnaweera PB, de Silva ED, Williams DE, Andersen RJ. Antimicrobial activities of endophytic fungi obtained from the arid zone invasive plant Opuntia dillenii and the isolation of equisetin, from endophytic Fusarium sp. Bmc Complementary and Alternative Medicine. 15: 220. PMID 26160390 DOI: 10.1186/s12906-015-0722-4  0.64
2015 Santos MF, Harper PM, Williams DE, Mesquita JT, Pinto ÉG, da Costa-Silva TA, Hajdu E, Ferreira AG, Santos RA, Murphy PJ, Andersen RJ, Tempone AG, Berlinck RG. Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula. Journal of Natural Products. 78: 1101-12. PMID 25924111 DOI: 10.1021/acs.jnatprod.5b00070  0.64
2015 Ratnaweera PB, Williams DE, Patrick BO, de Silva ED, Andersen RJ. Solanioic Acid, an Antibacterial Degraded Steroid Produced in Culture by the Fungus Rhizoctonia solani Isolated from Tubers of the Medicinal Plant Cyperus rotundus. Organic Letters. 17: 2074-7. PMID 25860081 DOI: 10.1021/acs.orglett.5b00596  0.64
2015 Piotrowski JS, Simpkins SW, Li SC, Deshpande R, McIlwain SJ, Ong IM, Myers CL, Boone C, Andersen RJ. Chemical genomic profiling via barcode sequencing to predict compound mode of action. Methods in Molecular Biology (Clifton, N.J.). 1263: 299-318. PMID 25618354 DOI: 10.1007/978-1-4939-2269-7_23  0.64
2015 Veale CG, Zoraghi R, Young RM, Morrison JP, Pretheeban M, Lobb KA, Reiner NE, Andersen RJ, Davies-Coleman MT. Synthetic analogues of the marine bisindole deoxytopsentin: potent selective inhibitors of MRSA pyruvate kinase. Journal of Natural Products. 78: 355-62. PMID 25372480 DOI: 10.1021/np500755v  0.64
2015 Rodriguez JPG, Williams DE, Sabater ID, Bonugli-Santos RC, Sette LD, Andersen RJ, Berlinck RGS. The marine-derived fungus Tinctoporellus sp. CBMAI 1061 degrades the dye Remazol Brilliant Blue R producing anthraquinones and unique tremulane sesquiterpenes Rsc Advances. 5: 66360-66366. DOI: 10.1039/c5ra13580j  0.64
2015 Weerasinghe AJ, Wickramasinghe A, Carr G, Williams D, Andersen R, Karunaratne V. Gardinerin, a biologically active acetogenin from the sri lankan goniothalamus Gardineri Hook. F. and Thomson International Journal of Pharmacy and Pharmaceutical Sciences. 7: 459-461.  0.64
2014 Centko RM, Steinø A, Rosell FI, Patrick BO, de Voogd N, Mauk AG, Andersen RJ. Indoleamine 2,3-dioxygenase inhibitors isolated from the sponge Xestospongia vansoesti: structure elucidation, analogue synthesis, and biological activity. Organic Letters. 16: 6480-3. PMID 25495618 DOI: 10.1021/ol503337f  0.64
2014 Du YL, Williams DE, Patrick BO, Andersen RJ, Ryan KS. Reconstruction of cladoniamide biosynthesis reveals nonenzymatic routes to bisindole diversity. Acs Chemical Biology. 9: 2748-54. PMID 25333917 DOI: 10.1021/cb500728h  0.64
2014 Banuelos CA, Lal A, Tien AH, Shah N, Yang YC, Mawji NR, Meimetis LG, Park J, Kunzhong J, Andersen RJ, Sadar MD. Characterization of niphatenones that inhibit androgen receptor N-terminal domain. Plos One. 9: e107991. PMID 25268119 DOI: 10.1371/journal.pone.0107991  0.64
2014 Boonnak N, Chantrapromma S, Fun HK, Yuenyongsawad S, Patrick BO, Maneerat W, Williams DE, Andersen RJ. Three types of cytotoxic natural caged-scaffolds: pure enantiomers or partial racemates. Journal of Natural Products. 77: 1562-71. PMID 24940955 DOI: 10.1021/np400996k  0.64
2014 Mercado-Marin EV, Garcia-Reynaga P, Romminger S, Pimenta EF, Romney DK, Lodewyk MW, Williams DE, Andersen RJ, Miller SJ, Tantillo DJ, Berlinck RG, Sarpong R. Total synthesis and isolation of citrinalin and cyclopiamine congeners. Nature. 509: 318-24. PMID 24828190 DOI: 10.1038/nature13273  0.64
2014 Ratnaweera PB, Williams DE, de Silva ED, Wijesundera RL, Dalisay DS, Andersen RJ. Helvolic acid, an antibacterial nortriterpenoid from a fungal endophyte, Xylaria sp. of orchid Anoectochilus setaceus endemic to Sri Lanka. Mycology. 5: 23-28. PMID 24772371 DOI: 10.1080/21501203.2014.892905  0.64
2014 Centko RM, Williams DE, Patrick BO, Akhtar Y, Garcia Chavez MA, Wang YA, Isman MB, de Silva ED, Andersen RJ. Dhilirolides E-N, meroterpenoids produced in culture by the fungus Penicillium purpurogenum collected in Sri Lanka: structure elucidation, stable isotope feeding studies, and insecticidal activity. The Journal of Organic Chemistry. 79: 3327-35. PMID 24684453 DOI: 10.1021/jo4024039  0.64
2014 Shin U, Williams DE, Kozakov D, Hall DR, Beglov D, Vajda S, Andersen RJ, Pelletier J. Stimulators of translation identified during a small molecule screening campaign. Analytical Biochemistry. 447: 6-14. PMID 24513115 DOI: 10.1016/j.ab.2013.10.026  0.64
2014 Fung SY, Sofiyev V, Schneiderman J, Hirschfeld AF, Victor RE, Woods K, Piotrowski JS, Deshpande R, Li SC, de Voogd NJ, Myers CL, Boone C, Andersen RJ, Turvey SE. Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis. Acs Chemical Biology. 9: 247-57. PMID 24117378 DOI: 10.1021/cb400740c  0.64
2014 Pereira FR, Santos MFC, Williams DE, Andersen RJ, Padula V, Ferreira AG, Berlinck RGS. Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus Journal of the Brazilian Chemical Society. 25: 788-794. DOI: 10.5935/0103-5053.20140037  0.64
2014 Ratnayake R, Perera D, Nedra Karunaratne D, Wijesundara DSA, Carr G, Williams DE, Andersen RJ, Karunaratne V. Antioxidant activity and a new butanolide from the primitive endemic genus Hortonia Journal of the National Science Foundation of Sri Lanka. 42: 253-256. DOI: 10.4038/jnsfsr.v42i3.7402  0.64
2014 Banuelos CA, Lal A, Tien AH, Shah N, Yang YC, Mawji NR, Meimetis LG, Park J, Kunzhong J, Andersen RJ, Sadar MD. Characterization of niphatenones that inhibit androgen receptor n-terminal domain Plos One. 9. DOI: 10.1371/journal.pone.010799  0.64
2014 Veale CGL, Lobb KA, Zoraghi R, Morrison JP, Reiner NE, Andersen RJ, Davies-Coleman MT. Synthesis and MRSA PK inhibitory activity of thiazole containing deoxytopsentin analogues Tetrahedron. 70: 7845-7853. DOI: 10.1016/j.tet.2014.09.007  0.64
2013 Dalisay DS, Williams DE, Wang XL, Centko R, Chen J, Andersen RJ. Marine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural products. Plos One. 8: e77078. PMID 24130838 DOI: 10.1371/journal.pone.0077078  0.64
2013 Daoust J, Chen M, Wang M, Williams DE, Garcia Chavez MA, Wang YA, Merchant CE, Fontana A, Kieffer TJ, Andersen RJ. Sesterterpenoids isolated from a northeastern Pacific Phorbas sp. The Journal of Organic Chemistry. 78: 8267-73. PMID 23941043 DOI: 10.1021/jo4014589  0.64
2013 Du YL, Dalisay DS, Andersen RJ, Ryan KS. N-carbamoylation of 2,4-diaminobutyrate reroutes the outcome in padanamide biosynthesis. Chemistry & Biology. 20: 1002-11. PMID 23911586 DOI: 10.1016/j.chembiol.2013.06.013  0.64
2013 Forestieri R, Donohue E, Balgi A, Roberge M, Andersen RJ. Synthesis of clionamine B, an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Organic Letters. 15: 3918-21. PMID 23869546 DOI: 10.1021/ol4016783  0.64
2013 Praman S, Mulvany MJ, Williams DE, Andersen RJ, Jansakul C. Crude extract and purified components isolated from the stems of Tinospora crispa exhibit positive inotropic effects on the isolated left atrium of rats. Journal of Ethnopharmacology. 149: 123-32. PMID 23778316 DOI: 10.1016/j.jep.2013.06.010  0.64
2013 Myung JK, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ, Sadar MD. An androgen receptor N-terminal domain antagonist for treating prostate cancer. The Journal of Clinical Investigation. 123: 2948-60. PMID 23722902 DOI: 10.1172/JCI66398  0.64
2013 Yang YC, Meimetis LG, Tien AH, Mawji NR, Carr G, Wang J, Andersen RJ, Sadar MD. Spongian diterpenoids inhibit androgen receptor activity. Molecular Cancer Therapeutics. 12: 621-31. PMID 23443807 DOI: 10.1158/1535-7163.MCT-12-0978  0.64
2013 Loosley BC, Andersen RJ, Dake GR. Total synthesis of cladoniamide G. Organic Letters. 15: 1152-4. PMID 23413919 DOI: 10.1021/ol400055v  0.64
2013 Austin P, Freeman SA, Gray CA, Gold MR, Vogl AW, Andersen RJ, Roberge M, Roskelley CD. The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner. Molecular Cancer Research : McR. 11: 530-40. PMID 23399642 DOI: 10.1158/1541-7786.MCR-12-0385  0.64
2013 Zimmerman C, Austin P, Khong A, McLeod S, Bean B, Forestieri R, Andersen RJ, Jan E, Roberge M, Roskelley CD. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. Experimental Cell Research. 319: 908-17. PMID 23333560 DOI: 10.1016/j.yexcr.2013.01.005  0.64
2013 Williams DE, Dalisay DS, Li F, Amphlett J, Maneerat W, Chavez MA, Wang YA, Matainaho T, Yu W, Brown PJ, Arrowsmith CH, Vedadi M, Andersen RJ. Nahuoic acid A produced by a Streptomyces sp. isolated from a marine sediment is a selective SAM-competitive inhibitor of the histone methyltransferase SETD8. Organic Letters. 15: 414-7. PMID 23272941 DOI: 10.1021/ol303416k  0.64
2012 Centko RM, Ramón-García S, Taylor T, Patrick BO, Thompson CJ, Miao VP, Andersen RJ. Ramariolides A-D, antimycobacterial butenolides isolated from the mushroom Ramaria cystidiophora. Journal of Natural Products. 75: 2178-82. PMID 23205944 DOI: 10.1021/np3006277  0.64
2012 Carlile GW, Keyzers RA, Teske KA, Robert R, Williams DE, Linington RG, Gray CA, Centko RM, Yan L, Anjos SM, Sampson HM, Zhang D, Liao J, Hanrahan JW, Andersen RJ, et al. Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. Chemistry & Biology. 19: 1288-99. PMID 23102222 DOI: 10.1016/j.chembiol.2012.08.014  0.64
2012 Williams DE, Steinø A, de Voogd NJ, Mauk AG, Andersen RJ. Halicloic acids A and B isolated from the marine sponge Haliclona sp. collected in the Philippines inhibit indoleamine 2,3-dioxygenase. Journal of Natural Products. 75: 1451-8. PMID 22873824 DOI: 10.1021/np300345j  0.64
2012 Khong A, Forestieri R, Williams DE, Patrick BO, Olmstead A, Svinti V, Schaeffer E, Jean F, Roberge M, Andersen RJ, Jan E. A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity. Plos One. 7: e39621. PMID 22761847 DOI: 10.1371/journal.pone.0039621  0.64
2012 Carr G, Williams DE, Ratnayake R, Bandara R, Wijesundara S, Tarling T, Balgi AD, Roberge M, Andersen RJ, Karunaratne V. Hortonones A to C, hydroazulenones from the genus Hortonia. Journal of Natural Products. 75: 1189-91. PMID 22626446 DOI: 10.1021/np200927k  0.64
2012 Lam KK, Zheng X, Forestieri R, Balgi AD, Nodwell M, Vollett S, Anderson HJ, Andersen RJ, Av-Gay Y, Roberge M. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. Plos Pathogens. 8: e1002691. PMID 22589723 DOI: 10.1371/journal.ppat.1002691  0.52
2012 Fonseca BD, Diering GH, Bidinosti MA, Dalal K, Alain T, Balgi AD, Forestieri R, Nodwell M, Rajadurai CV, Gunaratnam C, Tee AR, Duong F, Andersen RJ, Orlowski J, Numata M, et al. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. The Journal of Biological Chemistry. 287: 17530-45. PMID 22474287 DOI: 10.1074/jbc.M112.359638  0.64
2012 Praman S, Mulvany MJ, Williams DE, Andersen RJ, Jansakul C. Hypotensive and cardio-chronotropic constituents of Tinospora crispa and mechanisms of action on the cardiovascular system in anesthetized rats. Journal of Ethnopharmacology. 140: 166-78. PMID 22265931 DOI: 10.1016/j.jep.2012.01.006  0.64
2012 Meimetis LG, Williams DE, Mawji NR, Banuelos CA, Lal AA, Park JJ, Tien AH, Fernandez JG, de Voogd NJ, Sadar MD, Andersen RJ. Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity. Journal of Medicinal Chemistry. 55: 503-14. PMID 22148427 DOI: 10.1021/jm2014056  0.64
2012 Meimetis LG, Nodwell M, Yang L, Wang X, Wu J, Harwig C, Stenton GR, MacKenzie LF, MacRury T, Patrick BO, Ming-Lum A, Ong CJ, Krystal G, Mui ALF, Andersen RJ. Synthesis of SHIP1-activating analogs of the sponge meroterpenoid pelorol European Journal of Organic Chemistry. 5195-5207. DOI: 10.1002/ejoc.201200631  0.64
2011 Zoraghi R, Worrall L, See RH, Strangman W, Popplewell WL, Gong H, Samaai T, Swayze RD, Kaur S, Vuckovic M, Finlay BB, Brunham RC, McMaster WR, Davies-Coleman MT, Strynadka NC, ... Andersen RJ, et al. Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities. The Journal of Biological Chemistry. 286: 44716-25. PMID 22030393 DOI: 10.1074/jbc.M111.289033  0.64
2011 Williams DE, Dalisay DS, Patrick BO, Matainaho T, Andrusiak K, Deshpande R, Myers CL, Piotrowski JS, Boone C, Yoshida M, Andersen RJ. Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment. Organic Letters. 13: 3936-9. PMID 21749075 DOI: 10.1021/ol2014494  0.64
2011 Li D, Carr G, Zhang Y, Williams DE, Amlani A, Bottriell H, Mui AL, Andersen RJ. Turnagainolides A and B, cyclic depsipeptides produced in culture by a Bacillus sp.: isolation, structure elucidation, and synthesis. Journal of Natural Products. 74: 1093-9. PMID 21539394 DOI: 10.1021/np200033y  0.64
2011 de Silva ED, Williams DE, Jayanetti DR, Centko RM, Patrick BO, Wijesundera RL, Andersen RJ. Dhilirolides A-D, meroterpenoids produced in culture by the fruit-infecting fungus Penicillium purpurogenum collected in Sri Lanka. Organic Letters. 13: 1174-7. PMID 21348535 DOI: 10.1021/ol200031t  0.64
2011 Williams DE, Loganzo F, Whitney L, Togias J, Harrison R, Singh MP, McDonald LA, Kathirgamanathar S, Karunaratne V, Andersen RJ. Depsides isolated from the Sri Lankan lichen Parmotrema sp. exhibit selective Plk1 inhibitory activity. Pharmaceutical Biology. 49: 296-301. PMID 21281249 DOI: 10.3109/13880209.2010.517540  0.64
2010 Pereira AR, Strangman WK, Marion F, Feldberg L, Roll D, Mallon R, Hollander I, Andersen RJ. Synthesis of phosphatidylinositol 3-kinase (PI3K) inhibitory analogues of the sponge meroterpenoid liphagal. Journal of Medicinal Chemistry. 53: 8523-33. PMID 21121631 DOI: 10.1021/jm100531u  0.64
2010 Pimenta EF, Vita-Marques AM, Tininis A, Seleghim MH, Sette LD, Veloso K, Ferreira AG, Williams DE, Patrick BO, Dalisay DS, Andersen RJ, Berlinck RG. Use of experimental design for the optimization of the production of new secondary metabolites by two Penicillium species. Journal of Natural Products. 73: 1821-32. PMID 21053938 DOI: 10.1021/np100470h  0.64
2010 Nodwell M, Zimmerman C, Roberge M, Andersen RJ. Synthetic analogues of the microtubule-stabilizing sponge alkaloid ceratamine A are more active than the natural product. Journal of Medicinal Chemistry. 53: 7843-51. PMID 20945907 DOI: 10.1021/jm101012q  0.64
2010 Hill JA, Szabat M, Hoesli CA, Gage BK, Yang YH, Williams DE, Riedel MJ, Luciani DS, Kalynyak TB, Tsai K, Ao Z, Andersen RJ, Warnock GL, Piret JM, Kieffer TJ, et al. A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression. Plos One. 5: e12958. PMID 20886041 DOI: 10.1371/journal.pone.0012958  0.64
2010 Daoust J, Fontana A, Merchant CE, de Voogd NJ, Patrick BO, Kieffer TJ, Andersen RJ. Ansellone A, a sesterterpenoid isolated from the nudibranch Cadlina luteromarginata and the sponge Phorbas sp., activates the cAMP signaling pathway. Organic Letters. 12: 3208-11. PMID 20560657 DOI: 10.1021/ol101151f  0.64
2010 Andersen RJ, Mawji NR, Wang J, Wang G, Haile S, Myung JK, Watt K, Tam T, Yang YC, Bañuelos CA, Williams DE, McEwan IJ, Wang Y, Sadar MD. Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor. Cancer Cell. 17: 535-46. PMID 20541699 DOI: 10.1016/j.ccr.2010.04.027  0.64
2010 Austin P, Heller M, Williams DE, McIntosh LP, Vogl AW, Foster LJ, Andersen RJ, Roberge M, Roskelley CD. Release of membrane-bound vesicles and inhibition of tumor cell adhesion by the peptide Neopetrosiamide A. Plos One. 5: e10836. PMID 20520768 DOI: 10.1371/journal.pone.0010836  0.64
2010 Liu H, Boudreau MA, Zheng J, Whittal RM, Austin P, Roskelley CD, Roberge M, Andersen RJ, Vederas JC. Chemical synthesis and biological activity of the neopetrosiamides and their analogues: revision of disulfide bond connectivity. Journal of the American Chemical Society. 132: 1486-7. PMID 20073461 DOI: 10.1021/ja9102925  0.64
2010 Carr G, Williams DE, Díaz-Marrero AR, Patrick BO, Bottriell H, Balgi AD, Donohue E, Roberge M, Andersen RJ. Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy. Journal of Natural Products. 73: 422-7. PMID 20028134 DOI: 10.1021/np900632r  0.64
2010 Thadhani VM, Choudhary MI, Andersen RJ, Karunaratne V. Novel entry into 5-decarboxydibenzofurans via Smiles rearrangement of the lichen para-depside, erythrin Journal of Chemical Research. 154-157. DOI: 10.3184/030823410X12677394014276  0.64
2010 Williams DE, Amlani A, Dewi AS, Patrick BO, Van Ofwegen L, Mui ALF, Andersen RJ. Australin e isolated from the soft coral cladiella sp. collected in pohnpei activates the inositol 5-phosphatase SHIP1 Australian Journal of Chemistry. 63: 895-900. DOI: 10.1071/CH10053  0.64
2009 Forestieri R, Merchant CE, de Voogd NJ, Matainaho T, Kieffer TJ, Andersen RJ. Alotaketals A and B, sesterterpenoids from the marine sponge Hamigera species that activate the cAMP cell signaling pathway. Organic Letters. 11: 5166-9. PMID 19873990 DOI: 10.1021/ol902066e  0.64
2009 Williams DE, Marques SO, Hajdu E, Peixinho S, Andersen RJ, Berlinck RG. Pyrodysinoic acid derivatives from the marine sponge Dysidea robusta. Journal of Natural Products. 72: 1691-4. PMID 19722506 DOI: 10.1021/np900033v  0.64
2009 Kennah M, Yau TY, Nodwell M, Krystal G, Andersen RJ, Ong CJ, Mui AL. Activation of SHIP via a small molecule agonist kills multiple myeloma cells. Experimental Hematology. 37: 1274-83. PMID 19703514 DOI: 10.1016/j.exphem.2009.08.001  0.64
2009 Matsui Y, Hadaschik BA, Fazli L, Andersen RJ, Gleave ME, So AI. Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer. Molecular Cancer Therapeutics. 8: 2402-11. PMID 19625496 DOI: 10.1158/1535-7163.MCT-09-0148  0.64
2009 Williams DE, Yu K, Behrisch HW, Van Soest R, Andersen RJ. Rolloamides A and B, cytotoxic cyclic heptapeptides isolated from the Caribbean marine sponge Eurypon laughlini. Journal of Natural Products. 72: 1253-7. PMID 19583251 DOI: 10.1021/np900121m  0.64
2009 Carr G, Tay W, Bottriell H, Andersen SK, Mauk AG, Andersen RJ. Plectosphaeroic acids A, B, and C, indoleamine 2,3-dioxygenase inhibitors produced in culture by a marine isolate of the fungus Plectosphaerella cucumerina. Organic Letters. 11: 2996-9. PMID 19537768 DOI: 10.1021/ol900972j  0.64
2009 Williams DE, Hollander I, Feldberg L, Frommer E, Mallon R, Tahir A, van Soest R, Andersen RJ. Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens. Journal of Natural Products. 72: 1106-9. PMID 19485329 DOI: 10.1021/np900042r  0.64
2009 Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JL, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, et al. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds. Nature Biotechnology. 27: 369-77. PMID 19349972 DOI: 10.1038/nbt.1534  0.64
2009 Pereira A, Pfeifer TA, Grigliatti TA, Andersen RJ. Functional cell-based screening and saturation transfer double-difference NMR have identified haplosamate A as a cannabinoid receptor agonist. Acs Chemical Biology. 4: 139-44. PMID 19175306 DOI: 10.1021/cb800264k  0.64
2009 Nodwell M, Pereira A, Riffell JL, Zimmerman C, Patrick BO, Roberge M, Andersen RJ. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. The Journal of Organic Chemistry. 74: 995-1006. PMID 19128042 DOI: 10.1021/jo802322s  0.64
2008 Díaz-Marrero AR, Matainaho T, van Soest R, Roberge M, Andersen RJ. Scalarane-based metabolites isolated from the antimitotic extract of the marine sponge Hyrtios erectus. Natural Product Research. 22: 1304-9. PMID 19023786 DOI: 10.1080/14786410701824023  0.64
2008 Wong JW, McPhail LT, Brastianos HC, Andersen RJ, Ramer MS, O'Connor TP. A novel diketopiperazine stimulates sprouting of spinally projecting axons. Experimental Neurology. 214: 331-40. PMID 18926822 DOI: 10.1016/j.expneurol.2008.08.020  0.64
2008 Sadar MD, Williams DE, Mawji NR, Patrick BO, Wikanta T, Chasanah E, Irianto HE, Soest RV, Andersen RJ. Sintokamides A to E, chlorinated peptides from the sponge Dysidea sp. that inhibit transactivation of the N-terminus of the androgen receptor in prostate cancer cells. Organic Letters. 10: 4947-50. PMID 18834139 DOI: 10.1021/ol802021w  0.64
2008 Volgraf M, Lumb JP, Brastianos HC, Carr G, Chung MK, Münzel M, Mauk AG, Andersen RJ, Trauner D. Biomimetic synthesis of the IDO inhibitors exiguamine A and B. Nature Chemical Biology. 4: 535-7. PMID 18677305 DOI: 10.1038/nchembio.107  0.64
2008 Williams DE, Davies J, Patrick BO, Bottriell H, Tarling T, Roberge M, Andersen RJ. Cladoniamides A-G, tryptophan-derived alkaloids produced in culture by Streptomyces uncialis. Organic Letters. 10: 3501-4. PMID 18646774 DOI: 10.1021/ol801274c  0.64
2008 Keyzers RA, Daoust J, Davies-Coleman MT, Van Soest R, Balgi A, Donohue E, Roberge M, Andersen RJ. Autophagy-modulating aminosteroids isolated from the sponge Cliona celata. Organic Letters. 10: 2959-62. PMID 18553912 DOI: 10.1021/ol800937u  0.64
2008 Carr G, Chung MK, Mauk AG, Andersen RJ. Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A. Journal of Medicinal Chemistry. 51: 2634-7. PMID 18393489 DOI: 10.1021/jm800143h  0.64
2008 Hadaschik BA, Adomat H, Fazli L, Fradet Y, Andersen RJ, Gleave ME, So AI. Intravesical chemotherapy of high-grade bladder cancer with HTI-286, a synthetic analogue of the marine sponge product hemiasterlin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1510-8. PMID 18316576 DOI: 10.1158/1078-0432.CCR-07-4475  0.64
2008 Nodwell M, Riffell JL, Roberge M, Andersen RJ. Synthesis of antimitotic analogs of the microtubule stabilizing sponge alkaloid ceratamine A. Organic Letters. 10: 1051-4. PMID 18278926 DOI: 10.1021/ol7030284  0.64
2008 Hadaschik BA, Ettinger S, Sowery RD, Zoubeidi A, Andersen RJ, Roberge M, Gleave ME. Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. International Journal of Cancer. Journal International Du Cancer. 122: 2368-76. PMID 18240145 DOI: 10.1002/ijc.23406  0.64
2008 Tarling CA, Woods K, Zhang R, Brastianos HC, Brayer GD, Andersen RJ, Withers SG. The search for novel human pancreatic alpha-amylase inhibitors: high-throughput screening of terrestrial and marine natural product extracts. Chembiochem : a European Journal of Chemical Biology. 9: 433-8. PMID 18214874 DOI: 10.1002/cbic.200700470  0.64
2008 Wong JW, Brastianos HC, Andersen RJ, O'Connor TP. A high-throughput screen to identify novel compounds to promote neurite outgrowth. Journal of Neuroscience Methods. 169: 34-42. PMID 18178254 DOI: 10.1016/j.jneumeth.2007.11.013  0.64
2008 Sturgeon CM, Cinel B, Díaz-Marrero AR, McHardy LM, Ngo M, Andersen RJ, Roberge M. Abrogation of ionizing radiation-induced G2 checkpoint and inhibition of nuclear export by Cryptocarya pyrones. Cancer Chemotherapy and Pharmacology. 61: 407-13. PMID 17440726 DOI: 10.1007/s00280-007-0483-y  0.64
2008 Ratnayake R, Ratnayake Bandara BM, Wijesundara DSA, Carr G, Andersen RJ, Karunaratne V. Four new butanolide derivatives from Hortonia, a genus endemic to Sri Lanka Journal of Chemical Research. 134-136. DOI: 10.3184/030823408X298490  0.64
2008 Puvanendran S, Wickramasinghe A, Karunaratne DN, Carr G, Wijesundara DSA, Andersen R, Karunaratne V. Antioxidant constituents from Xylopia championii Pharmaceutical Biology. 46: 352-355. DOI: 10.1080/13880200801887989  0.64
2008 Ratnayake R, Jayasinghe S, Ratnayake Bandara BM, Andersen RJ, Karunaratne V. Complete 2D NMR assignment and antifungal activity of ishwarane isolated from Hortonia, a genus endemic to Sri Lanka Journal of the National Science Foundation of Sri Lanka. 36: 109-112.  0.64
2008 Bombuwela K, Kathirgamanathar S, Thadhani V, Jayalal RGU, Adikaram NKB, Wijesundara DSA, Andersen R, Wolseley P, Karunaratne V. Chemistry of Heterodermia microphylla, a lichen new to Sri Lanka Journal of the National Science Foundation of Sri Lanka. 36: 251-252.  0.64
2007 Desjardine K, Pereira A, Wright H, Matainaho T, Kelly M, Andersen RJ. Tauramamide, a lipopeptide antibiotic produced in culture by Brevibacillus laterosporus isolated from a marine habitat: structure elucidation and synthesis. Journal of Natural Products. 70: 1850-3. PMID 18044840 DOI: 10.1021/np070209r  0.64
2007 Williams DE, Keyzers RA, Warabi K, Desjardine K, Riffell JL, Roberge M, Andersen RJ. Spirastrellolides C to G: macrolides obtained from the marine sponge Spirastrella coccinea. The Journal of Organic Chemistry. 72: 9842-5. PMID 17988148 DOI: 10.1021/jo7018174  0.64
2007 Carr G, Raszek M, Van Soest R, Matainaho T, Shopik M, Holmes CF, Andersen RJ. Protein phosphatase inhibitors isolated from Spongia irregularis collected in Papua New Guinea. Journal of Natural Products. 70: 1812-5. PMID 17979246 DOI: 10.1021/np0702887  0.64
2007 Ong CJ, Ming-Lum A, Nodwell M, Ghanipour A, Yang L, Williams DE, Kim J, Demirjian L, Qasimi P, Ruschmann J, Cao LP, Ma K, Chung SW, Duronio V, Andersen RJ, et al. Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells. Blood. 110: 1942-9. PMID 17502453 DOI: 10.1182/blood-2007-03-079699  0.64
2007 Williams DE, Sturgeon CM, Roberge M, Andersen RJ. Nigricanosides A and B, antimitotic glycolipids isolated from the green alga Avrainvillea nigricans collected in Dominica. Journal of the American Chemical Society. 129: 5822-3. PMID 17439220 DOI: 10.1021/ja0715187  0.64
2007 Warabi K, Patrick BO, Austin P, Roskelley CD, Roberge M, Andersen RJ. Strongylophorine-26, an inhibitor of cancer cell Invasion: SAR revealed by synthesis of analogues. Journal of Natural Products. 70: 736-40. PMID 17407351 DOI: 10.1021/np060481l  0.64
2007 Brastianos HC, Sturgeon CM, Roberge M, Andersen RJ. Inhibition of the G2 DNA damage checkpoint by oliveroline isolated from Duguetia odorata. Journal of Natural Products. 70: 287-8. PMID 17315964 DOI: 10.1021/np060285e  0.64
2007 Warabi K, Williams DE, Patrick BO, Roberge M, Andersen RJ. Spirastrellolide B reveals the absolute configuration of the spirastrellolide macrolide core. Journal of the American Chemical Society. 129: 508-9. PMID 17227011 DOI: 10.1021/ja068271i  0.64
2007 Diaz-Marrero AR, Gray CA, McHardy L, Warabi K, Roberge M, Andersen RJ. Antiangiogenic Alkaloids from Marine Organisms Modern Alkaloids: Structure, Isolation, Synthesis and Biology. 233-269. DOI: 10.1002/9783527621071.ch9  0.64
2007 De Lira SP, Seleghim MHR, Williams DE, Marion F, Hamill P, Jean F, Andersen RJ, Hajdu E, Berlinck RGS. A SARS-coronovirus 3CL protease inhibitor isolated from the marine sponge Axinella cf. corrugata: Structure elucidation and synthesis Journal of the Brazilian Chemical Society. 18: 440-443.  0.64
2006 Rundle NT, Nelson J, Flory MR, Joseph J, Th'ng J, Aebersold R, Dasso M, Andersen RJ, Roberge M. An ent-kaurene that inhibits mitotic chromosome movement and binds the kinetochore protein ran-binding protein 2. Acs Chemical Biology. 1: 443-50. PMID 17168522 DOI: 10.1021/cb600196w  0.64
2006 Brastianos HC, Vottero E, Patrick BO, Van Soest R, Matainaho T, Mauk AG, Andersen RJ. Exiguamine A, an indoleamine-2,3-dioxygenase (IDO) inhibitor isolated from the marine sponge Neopetrosia exigua. Journal of the American Chemical Society. 128: 16046-7. PMID 17165752 DOI: 10.1021/ja067211+  0.64
2006 Andersen RJ, Desjardine K, Woods K. Skin chemistry of nudibranchs from the west coast of North America. Progress in Molecular and Subcellular Biology. 43: 277-301. PMID 17153348  0.64
2006 Pereira A, Vottero E, Roberge M, Mauk AG, Andersen RJ. Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata. Journal of Natural Products. 69: 1496-9. PMID 17067170 DOI: 10.1021/np060111x  0.64
2006 Parsons AB, Lopez A, Givoni IE, Williams DE, Gray CA, Porter J, Chua G, Sopko R, Brost RL, Ho CH, Wang J, Ketela T, Brenner C, Brill JA, Fernandez GE, ... ... Andersen RJ, et al. Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast. Cell. 126: 611-25. PMID 16901791 DOI: 10.1016/j.cell.2006.06.040  0.64
2006 Diaz-Marrero AR, Austin P, Van Soest R, Matainaho T, Roskelley CD, Roberge M, Andersen RJ. Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp. Organic Letters. 8: 3749-52. PMID 16898808 DOI: 10.1021/ol061333p  0.64
2006 Vottero E, Balgi A, Woods K, Tugendreich S, Melese T, Andersen RJ, Mauk AG, Roberge M. Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast. Biotechnology Journal. 1: 282-8. PMID 16897708 DOI: 10.1002/biot.200600001  0.64
2006 Barsby T, Warabi K, Sørensen D, Zimmerman WT, Kelly MT, Andersen RJ. The Bogorol family of antibiotics: template-based structure elucidation and a new approach to positioning enantiomeric pairs of amino acids. The Journal of Organic Chemistry. 71: 6031-7. PMID 16872185 DOI: 10.1021/jo060667p  0.64
2006 Murphy S, Larrivée B, Pollet I, Craig KS, Williams DE, Huang XH, Abbott M, Wong F, Curtis C, Conrads TP, Veenstra T, Puri M, Hsiang Y, Roberge M, Andersen RJ, et al. Identification of sokotrasterol sulfate as a novel proangiogenic steroid. Circulation Research. 99: 257-65. PMID 16794189 DOI: 10.1161/01.RES.0000233316.17882.33  0.64
2006 Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/np050192h  0.64
2006 Marion F, Williams DE, Patrick BO, Hollander I, Mallon R, Kim SC, Roll DM, Feldberg L, Van Soest R, Andersen RJ. Liphagal, a Selective inhibitor of PI3 kinase alpha isolated from the sponge akacoralliphaga: structure elucidation and biomimetic synthesis. Organic Letters. 8: 321-4. PMID 16408905 DOI: 10.1021/ol052744t  0.64
2005 Sturgeon CM, Craig K, Brown C, Rundle NT, Andersen RJ, Roberge M. Modulation of the G2 cell cycle checkpoint by sesquiterpene lactones psilostachyins A and C isolated from the common ragweed Ambrosia artemisiifolia. Planta Medica. 71: 938-43. PMID 16254826 DOI: 10.1055/s-2005-873109  0.64
2005 Williams DE, Austin P, Diaz-Marrero AR, Soest RV, Matainaho T, Roskelley CD, Roberge M, Andersen RJ. Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Organic Letters. 7: 4173-6. PMID 16146380 DOI: 10.1021/ol051524c  0.64
2005 Kathirgamanathar S, Williams DE, Andersen RJ, Bombuwela K, De Silva D, Karunaratne V. Beta-orcinol depsidones from the lichen Usnea sp. from Sri Lanka. Natural Product Research. 19: 695-701. PMID 16076641 DOI: 10.1080/14786410512331330639  0.48
2005 McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M. Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8. PMID 15897241 DOI: 10.1158/1535-7163.MCT-04-0310  0.64
2005 Karjala G, Chan Q, Manzo E, Andersen RJ, Roberge M. Ceratamines, structurally simple microtubule-stabilizing antimitotic agents with unusual cellular effects. Cancer Research. 65: 3040-3. PMID 15833830 DOI: 10.1158/0008-5472.CAN-04-4369  0.64
2005 Williams DE, Patrick BO, Behrisch HW, Van Soest R, Roberge M, Andersen RJ. Dominicin, a cyclic octapeptide, and laughine, a bromopyrrole alkaloid, isolated from the Caribbean marine sponge Eurypon laughlini. Journal of Natural Products. 68: 327-30. PMID 15787430 DOI: 10.1021/np049711r  0.6
2005 Yang L, Williams DE, Mui A, Ong C, Krystal G, van Soest R, Andersen RJ. Synthesis of pelorol and analogues: activators of the inositol 5-phosphatase SHIP. Organic Letters. 7: 1073-6. PMID 15760142 DOI: 10.1021/ol047316m  0.64
2004 Macmillan JB, Linington RG, Andersen RJ, Molinski TF. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angewandte Chemie (International Ed. in English). 43: 5946-51. PMID 15547902 DOI: 10.1002/anie.200461158  0.64
2003 Linington RG, Williams DE, Tahir A, van Soest R, Andersen RJ. Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: structure elucidation, synthesis, and biogenetic implications. Organic Letters. 5: 2735-8. PMID 12868902 DOI: 10.1021/ol034950b  0.64
2002 Linington RG, Robertson M, Gauthier A, Finlay BB, van Soest R, Andersen RJ. Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. Organic Letters. 4: 4089-92. PMID 12423093 DOI: 10.1021/ol0268337  0.64
2002 Williams DE, Craig KS, Patrick B, McHardy LM, van Soest R, Roberge M, Andersen RJ. Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. The Journal of Organic Chemistry. 67: 245-58. PMID 11777468 DOI: 10.1021/jo016101c  0.64
2001 Rundle NT, Xu L, Andersen RJ, Roberge M. G2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin. The Journal of Biological Chemistry. 276: 48231-6. PMID 11572854 DOI: 10.1074/jbc.M103990200  0.64
2001 Curman D, Cinel B, Williams DE, Rundle N, Block WD, Goodarzi AA, Hutchins JR, Clarke PR, Zhou BB, Lees-Miller SP, Andersen RJ, Roberge M. Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. The Journal of Biological Chemistry. 276: 17914-9. PMID 11279124 DOI: 10.1074/jbc.M100728200  0.64
2000 Roberge M, Cinel B, Anderson HJ, Lim L, Jiang X, Xu L, Bigg CM, Kelly MT, Andersen RJ. Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts. Cancer Research. 60: 5052-8. PMID 11016628  0.64
2000 Cinel B, Roberge M, Behrisch H, van Ofwegen L, Castro CB, Andersen RJ. Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization. Organic Letters. 2: 257-60. PMID 10814296  0.64
1998 Roberge M, Berlinck RG, Xu L, Anderson HJ, Lim LY, Curman D, Stringer CM, Friend SH, Davies P, Vincent I, Haggarty SJ, Kelly MT, Britton R, Piers E, Andersen RJ. High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide. Cancer Research. 58: 5701-6. PMID 9865726  0.64
1977 Wratten SJ, Wolfe MS, Andersen RJ, Faulkner DJ. Antibiotic metabolites from a marine pseudomonad. Antimicrobial Agents and Chemotherapy. 11: 411-4. PMID 324390  0.48
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