Polymnia Georgiou - Publications

Affiliations: 
2015- University of Maryland School of Medicine, Baltimore, MD, United States 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Onisiforou A, Georgiou P, Zanos P. Role of group II metabotropic glutamate receptors in ketamine's antidepressant actions. Pharmacology, Biochemistry, and Behavior. 223: 173531. PMID 36841543 DOI: 10.1016/j.pbb.2023.173531  0.79
2023 Zanos P, Brown KA, Georgiou P, Yuan P, Zarate CA, Thompson SM, Gould TD. NMDA RECEPTOR ACTIVATION-DEPENDENT ANTIDEPRESSANT-RELEVANT BEHAVIORAL AND SYNAPTIC ACTIONS OF KETAMINE. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36596696 DOI: 10.1523/JNEUROSCI.1316-22.2022  0.81
2022 Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, et al. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nature Neuroscience. PMID 36042309 DOI: 10.1038/s41593-022-01146-x  0.754
2021 Troppoli TA, Zanos P, Georgiou P, Gould TD, Rudolph U, Thompson SM. Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. Biological Psychiatry. PMID 35120711 DOI: 10.1016/j.biopsych.2021.11.024  0.789
2021 Osman A, Zuffa S, Walton G, Fagbodun E, Zanos P, Georgiou P, Kitchen I, Swann J, Bailey A. Post-weaning A1/A2 β-casein milk intake modulates depressive-like behavior, brain μ-opioid receptors, and the metabolome of rats. Iscience. 24: 103048. PMID 34585111 DOI: 10.1016/j.isci.2021.103048  0.746
2021 Highland JN, Zanos P, Riggs LM, Georgiou P, Clark SM, Morris PJ, Moaddel R, Thomas CJ, Zarate CA, Pereira EFR, Gould TD. Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791. PMID 33674359 DOI: 10.1124/pharmrev.120.000149  0.776
2019 Krimmel SR, Zanos P, Georgiou P, Colloca L, Gould TD. Classical conditioning of antidepressant placebo effects in mice. Psychopharmacology. PMID 31422429 DOI: 10.1007/S00213-019-05347-4  0.788
2019 Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris PJ, Stewart BW, Thomas CJ, Thompson SM, Moaddel R, Gould TD. (R)-ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anesthetic doses. British Journal of Pharmacology. PMID 30941749 DOI: 10.1111/Bph.14683  0.751
2019 Highland JN, Zanos P, Georgiou P, Gould TD. Group II metabotropic glutamate receptor blockade promotes stress resilience in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30939596 DOI: 10.1038/S41386-019-0380-1  0.788
2019 Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD. ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867285 DOI: 10.1073/Pnas.1819540116  0.8
2019 Georgiou P, Zanos P, Jenne CE, Gould TD. Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation. Frontiers in Psychiatry. 10: 81. PMID 30863326 DOI: 10.3389/Fpsyt.2019.00081  0.801
2018 Zanos P, Keyworth H, Georgiou P, Kitchen I, Zimmer A, Bailey A. Chronic nicotine administration restores brain region specific up-regulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia. The European Journal of Neuroscience. PMID 30218618 DOI: 10.1111/Ejn.14155  0.768
2018 Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I. 7B2 chaperone knockout in APP model mice results in reduced plaque burden. Scientific Reports. 8: 9813. PMID 29955078 DOI: 10.1038/S41598-018-28031-7  0.565
2018 Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/Pr.117.015198  0.772
2018 Rae M, Zanos P, Georgiou P, Chivers P, Bailey A, Camarini R. Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice. Neuropharmacology. PMID 29908241 DOI: 10.1016/J.Neuropharm.2018.06.013  0.76
2018 Wright VL, Georgiou P, Bailey A, Heal DJ, Bailey CP, Wonnacott S. Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding. Addiction Biology. PMID 29667304 DOI: 10.1111/Adb.12624  0.387
2018 García-Carmona JA, Georgiou P, Zanos P, Bailey A, Laorden ML. Methamphetamine withdrawal induces activation of CRF neurons in the brain stress system in parallel with an increased activity of cardiac sympathetic pathways. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 29383398 DOI: 10.1007/S00210-018-1470-Z  0.76
2018 Georgiou P, Zanos P, Jenne C, Highland J, Gerhard D, Duman R, Gould T. F102. Human Experimenter Sex Modulates Mouse Behavioral Responses to Stress and to the Antidepressant Ketamine Biological Psychiatry. 83: S277. DOI: 10.1016/J.Biopsych.2018.02.715  0.762
2018 Highland J, Zanos P, Georgiou P, Gould T. T89. Group II Metabotropic Glutamate Receptor Blockade Promotes Stress Resilience Biological Psychiatry. 83: S163. DOI: 10.1016/J.Biopsych.2018.02.425  0.759
2017 Keyworth H, Georgiou P, Zanos P, Rueda AV, Chen Y, Kitchen I, Camarini R, Cropley M, Bailey A. Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice. British Journal of Pharmacology. PMID 29266170 DOI: 10.1111/Bph.14068  0.771
2017 Georgiou P, Zanos P, Bhat S, Tracy JK, Merchenthaler IJ, McCarthy MM, Gould TD. Dopamine and Stress System Modulation of Sex Differences in Decision Making. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28741626 DOI: 10.1038/Npp.2017.161  0.758
2017 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KSS, Fang Y, Huang XP, Mayo CL, Albuquerque EX, et al. Zanos et al. reply. Nature. 546: E4-E5. PMID 28640272 DOI: 10.1038/Nature22085  0.733
2017 Gould TD, Georgiou P, Brenner LA, Brundin L, Can A, Courtet P, Donaldson ZR, Dwivedi Y, Guillaume S, Gottesman II, Kanekar S, Lowry CA, Renshaw PF, Rujescu D, Smith EG, et al. Animal models to improve our understanding and treatment of suicidal behavior. Translational Psychiatry. 7: e1092. PMID 28398339 DOI: 10.1038/Tp.2017.50  0.756
2017 Zanos P, Georgiou P, Weber C, Robinson F, Kouimtsidis C, Niforooshan R, Bailey A. Oxytocin and opioid addiction revisited: Old drug, new applications. British Journal of Pharmacology. PMID 28378414 DOI: 10.1111/Bph.13757  0.77
2017 Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM. A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice. Eneuro. 4. PMID 28275719 DOI: 10.1523/ENEURO.0285-16.2017  0.788
2017 Martynhak BJ, Hogben AL, Zanos P, Georgiou P, Andreatini R, Kitchen I, Archer SN, von Schantz M, Bailey A, van der Veen DR. Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(-/-) mice, but not wildtype mice. Scientific Reports. 7: 40399. PMID 28071711 DOI: 10.1038/Srep40399  0.748
2017 Camarini R, Rae M, Zanos P, Georgiou P, Chivers P, Bailey A. S14-2PARALLEL APPROACHES FOR OXYTOCIN AND ENVIRONMENTAL ENRICHMENT UPON ETHANOL’S REWARDING EFFECTS Alcohol and Alcoholism. 52: i4-i30. DOI: 10.1093/alcalc/agx075.52  0.727
2017 Bailey A, Georgiou P, Zanos P, Sklirou M, Kalk N, Lingford-Hughes A, Wells L. S10-1NEURO-INFLAMMATION AND ALCOHOL ADDICTION: CORRELATION WITH MEMORY AND MOTOR IMPAIRMENT Alcohol and Alcoholism. 52: i4-i30. DOI: 10.1093/alcalc/agx075.35  0.712
2017 Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer G, Alkondon M, Yuan P, Pribut H, Singh N, Dossou K, Fang Y, Huang X, Mayo C, Wainer I, et al. 790. Ketamine Exerts NMDAR Inhibition-Independent Antidepressant Actions via Its Hydroxynorketamine Metabolites Biological Psychiatry. 81: S321. DOI: 10.1016/J.Biopsych.2017.02.857  0.781
2016 Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, et al. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27834214 DOI: 10.1073/Pnas.1608432113  0.558
2016 Georgiou P, Zanos P, Hourani S, Kitchen I, Bailey A. Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. The European Journal of Neuroscience. PMID 27453431 DOI: 10.1111/Ejn.13348  0.756
2016 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. PMID 27144355 DOI: 10.1038/Nature17998  0.794
2016 Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Laorden ML, Bailey A. Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype. Neuropharmacology. PMID 26896754 DOI: 10.1016/J.Neuropharm.2016.02.012  0.793
2016 Zanos P, Georgiou P, Rojo Gonzalez L, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A. Emotional impairment and persistent up-regulation of mGlu5 receptor following morphine abstinence: implications of an mGlu5-MOPr interaction. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26861145 DOI: 10.1093/Ijnp/Pyw011  0.766
2015 Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Kieffer BL, Laorden ML, Bailey A. The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26475574 DOI: 10.1016/J.Euroneuro.2015.09.015  0.792
2015 Zanos P, Georgiou P, Metaxas A, Kitchen I, Winsky-Sommerer R, Bailey A. Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration. Neuroscience Letters. 600: 33-7. PMID 26037668 DOI: 10.1016/J.Neulet.2015.05.054  0.773
2015 Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine. Addiction Biology. PMID 25975203 DOI: 10.1111/Adb.12259  0.767
2014 Georgiou P, Zanos P, Ehteramyan M, Hourani S, Kitchen I, Maldonado R, Bailey A. Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice. Addiction Biology. PMID 25522112 DOI: 10.1111/Adb.12208  0.773
2014 Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 855-65. PMID 24129263 DOI: 10.1038/Npp.2013.285  0.783
2014 Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism. Pharmacology, Biochemistry, and Behavior. 119: 72-9. PMID 23680573 DOI: 10.1016/J.Pbb.2013.05.009  0.795
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